Bellwether 30 | Winter/Spring 1991

Center for Veterinary Critical Care Established

When the Veterinary Hospital of the University of Pennsylvania (VHUP) opened in 1981. the Emergency Service (ES) case load was less than 1.000 annually. Today about 40 percent of VHUP's patients require specialized care that involves theEmergency Service, Intensive Care Unit (ICU) and the Ane�thesia Sc:rvice,reflectingthehospitaPs role as a regionalcritical care referral cemer for companion animals. The annual case load bas grown to more than 8,000 in ES and over 1,200 in ICU.

To even better serve the patients' needs, the School, in November J990, created the Center for Veterinary Critical Care (CVCC), a multi-disciplinary unit within the Department of Clinical Studies at Philadelphia. The Center encompasses six facuJty positions, two each from anesthesia, ICU and ES, as weU as residents, nurses, technicians, students, and staff from each of the three services.

Veterinary emergency and intensive care have made great strides in the last few years. paraUelling developments in human medicine. By establishing the CVCC, the first whollyintegrated veterinary critical care unitin the world, Penn's Veterinary School is able to enhance and advance veterinary critical care. The Center fosters closer interaction between clinicians of the different services andfacilitates a smoother transfer of cases from one service to another. Further, through the continual involvement of the various clinicians in patient care at all three levels, more efficient coordination of treatment is achieved. The training program for students and residents is enhanced as the three services function as one unit.

The Emergency Service at VHUP is staffed 24 hours a day by specially trained nurses, residents, faculty and students, seven

days a week. This independent unit is equipped to provide acute care including CPR, oxygen support and ventilation, EKG, both direct and indirect blood pressure monjtoring, laboratorywork, radiologyand minor surgery. Emergency surgery is performed by surgery and anesthesia staff on call.

The Intensive Care Unit provides care to the sickest patients admitted though Emergency Services or other hospital services. It is staffed by specially trained nurses around the clock, seven days a week. The unit is equipped, and the nurses trained, to provide CPR, ventilation, peritoneal dialysis, parenteral or enteral nutrition, direct blood pressure monitoring, stat laboratory work, includjng arterial blood gases, and all routine support. It is, at this point, one of the most sophisticated Intensive Care Units at a veterinary hospital anywhere. ln addition to the nursing staff, two full-time medicine faculty work in the ICU exclusively, as well as a resident and

students. The anesthesia faculty provide additional supervision for surgery cases. Residents in critical careveterinarymedicine train in the Emergency Service, the Intensive Care Unit and rotate through anesthesia, medicine, cardiology and surgery. The residency program is three years in length. ln addition to even better patient care, the CVCC provides enhanced teaching for students and residents. Daily rounds are presented in each service and weekly combined ICU-ES care rounds are held to discuss cases seen in both services. These rounds involve staff from ICU, ES, cardiology. anesthesia, medicine, and surgery. There are also regularly scheduled critical care seminars where the critical care faculty and residents discuss ongoing research and topics of common interest, and assess new approaches to clinicalproblems. The CVCC is co-dirt"cted by Dr. Joan Hendricks, associate professor of medicine, and Dr. Alan Klide, associate professor and chief, section of anesthesia.

Scholarship Program in Veterinary Public Service Established

Robert F. Fairchild, New York. NY, has established the Lois F. Fairchild Scholarship Program in Veterinary Public Service at the School of VetennaryMedicine of the Uruversjty of Pennsylvania.

The scholarship program, in honor of Mr. Fairchild'smotherwhocaredgreatJyforanimalsand theirwelfare,isthefirstsuchprograminaveterinary school. lt is designed to encourage veterinarians to enterthefleldofpublicpracticeorserviceasa career goaL

Mr. Fairchild's motive to establish the endowment stemmed from the blending of his family'slifelonginterests,coupledwithasuggestion made by the family veterinarian, who commented that "the veterinaryprofession needs to attract youngpeople10publicservice, wheretheir skillsare criticallyneeded."Duringtheirliv�.hisfatherwas deeplycommittedtoeducation, whilehismotherwas devotedtoanimals.Mr. Fairchild,asanalumnusof The Collegeof ArtsandScjences.has closetieswith the University.

Theendowmentwhichcomesfromtheestateof \1r.Edgar\V B. Fairchild,providesfortuitionaid for oneJUntor and one senior student who have a '\trong commitmenr to public serv1ce. Scholarship recip1entsarcrequiredtopractice inthepublicsector foratleastoneyearfollowmggraduation.Areasof employment include such diverse areas as: epidemiology/publichealth; direct animal care for humanc/SPCA organizations (an intermhip here is not considered appropriate public practice); Peace Corps; Nauve American Projects of the AVMA; fcdcral/'itate,local govemmcm services: aquaria, zoosandwildlifeorganizations:servicetoSeeingEye organi1ations; and, World Health Organization.

..Weareemhus1asticabouttheLoisF.Fairchild Scholarship PrograminVeterinary PublicHealth." -.aidDeanEd"inJ.Andrews. "Wearecommittedto broadeningthewaysinwhichvetennarymedicineis integrated into a global society and this program challenges us to expand our collective recognition and understanding of 'public' veterinary medicine, and in turn, to teach and persuade others about its value."

Alumni Day

Alumni Day will be- held at Ne" Bolton Center on SalUrda)', May 18, 1991. Sa'c the c.late, end in your registrauon early, join the fun!

Theday willincludeac:uvit1e roreveryone -alumni,spous�.and children-:.o,b)all m�nns, bring the kids. tn addition to the Vetcrinary Medical Alumni Soc�ety' Annual Meeting, there will be a barbecue lunch. hayride�lcarriage rides, '' side ..addk exhibition. and outdoor game�. including volle)'ball, �oftball, and spe�1al game for the �ids.AwalkingloutofNBCam.ta lourolthe llagl�· Muc;eum (theoriginal DuPom mill • �uue, and gardens in Wilmington) nrc other activitie.;.

The annual Alumni Danner l>anewall follow in the evening at the Hotel DuPont in Wilmington.Weareinv\lingallouralumnito JOin U!> for an evening ofelegant dining and dllncing. (lhc hotel provides babysitting service,sovouneedn•tworryaboutthekids.)

From the Dean

Eacllyear Individual, aswellas societalper�ptioos of theworld aroundus change;ithasbeen arguedtbll "perception isreality."

One majorchll.llge in ocietyisour perception of our relationship with anlmsls.Justaswehave be,·omemoreawsreof ourenvironment. more acceptingofotber culturesM.Dd norms, and morewillingto chlllleage dogmaandthestatusquo,sotoobattew�efocusedon ourresponsibilities towardanimals.

Thefollowingisaquotation froma recent reportofaworkingpartyfortheCouncilforScience andSocletJinGreatBritain.Thequotationisfound ins bQoklet, Companion Animals in Society, publisl1cd by tile Oxford UniversityPress(1988).

"It is one ofthe moral assomptlons of our society (and of manyothers) thata duty e:dststo protet:ttheinterestsofsnimals,lhereb.tsettinglimits on wbal m•y bedonetotbem inorder to satisfy humanneed<tanddesires.Itinotnecessal)toinvest animalswithrightsillordertoassertandenforcethat duty.Thedar,an"se.sfromthelntellectWllllndmoral perceptionswhichareaproductofbumsnnarure."

A/Jetter understandingofhowwe useanimals heightens our sensiti"Vityandsharpen,,our moral perception.

If the onlygroupaddressingthisissueis c:omp�ofthoseweconsideranimalrights extnmits,dearlyourviewwilJbelnflumced,ifnot abjecl1)'biased,inonedirection.OnenHdonlylook at the untruths and distortions wblcbhave been printed byPETASJtd othergroupsregardingDr. AdrianMorrisonandhiscolleagut>sinotherSchools bereIllPenn. Despill!theactivists'allegations,Dr. Morrion hasbeenchosenastherecipientforthe ScientificFreedomandResponsibilityJlwsrdofthe AmericanAssociation fortheAdvancementof Sden(·e. Thisprestigious honor recognizuDr. Morri�on'scourage:mddetermin11tJon,inthefaceof persoulrisk, to defendtbe useof animalsin r�srch.

TheBeJIM·etherprovideus witha formlltto uplort with,-ou. our constituent:,, friendssnd clients.themanyaspectsandi ·ue$in'tlolvinganimal useinsociety.

Overthenext yearwe willprovide aseriesof articles to begin thisprocess ofprobing, education sud cbllllenge. Wewelcome your response tothis concept and thespecificissuesraised. TheSchool's nt•w/yinstitutedBioethic:sCommiueewi11t�alue,·our inputa�wedealwithvurinstitutionalperceptionand positionon Lh6Ccomplexandimportant is'>ues. TbanllJOU.

EdwinJ••4ndrew�. V.M.D., Ph.D.

Proposed State Funding Cuts

Go\>crnor Casey's proposed reduction in tbe University's state appropriataon has forced Penn to plan adjustments in its FY '92 budget. University President Hackney said. The adjustments, he announced, meanpostponementofnewconstruction andrenovation.somereductionin facultyandstaff. and a tuition increase a bit larger thnn planned.

Thegovernorproposeda49percenr cut-$18.6 mllJion-inPenn'sFY'92appropriatiOn,whichwas to have been $37.6 million. • 'The risk to the University is real and it requires importam programmatic and financsal choices. But above all. the academic mission and quality of the University must be preserved," Had.ne)' emphasued.

GovernorCaseyproposedthatPenn's107-yearold Vetcnnary School - the only one in the Commonwealth - lose nearly $7 million of its appropriation. "For one year, the Umversily will underwrite the vet school" by absorbing nearly $6 million of the shonfall, Hackney pledged. ''But if the appropnation is not restored, we will have to decide whether we can afford to conunue the school's operauon."

"WewillaggressivelysedrestoratiOnofthefull appropnauon to the University, which was to have matched the FY '91 level," Hackney satd. ..However, we must address lh.is difficuJ1y with the assumption that the cuts maynot be restored and that, given the climate in Harrisburg. the entire appropriation may be at risk over the next few years."

Hackney outlinedPenn'splan toaccommodate the proposed appropriations cut. At least 300 poitions will be cut, beginning immediately and continuing through 1992. The reduction m Penn's workforce, to be carried out by each o;chool and administrative area, will be achieved through a combination orattrition, reassignment, retirement, and layorrs. aU duectly related to cuts m programs and scrv1ces.

The University also needs to plan for a $6 million deficit in FY J92, brought about by the

proposed appropriations cut; it will be Penn''> ftrSt unbalanced budget in 15 years.

The Commonwealth's appropriations process beg�nswaththeGovernor'sproposabandcontinues overthenextseveral monthr.. Legislativecomminees take tec;timony, consider their own preferences, negotiate compromises, and eventually agree on amounts acceptable to both the Scmate and House. Given the Commonwealth's grim financial piCture and Governor Casey's stark proposal, the process may not be completed until late faJJ, after the first <>emesterofthe1992-93academicyearisweUunder way Ouralumni.friends,andchentswillhearfrom theSchoolshonly.Wewillaskthattheycontacttheir statelegJslatorstotopomtouthow devastatingthe proposed cut:>aretotheVeterinarySchool.Sincethe state appropriation for FY 91 is $15 million, the proposed$7 millioncutforFY92fromanoperating budget ofS45 millioniscatastrophic.Weneedyour help.WehopeyouwiUassistusby\\'ritingyourstate reprcsentathes in Harrisburg and tell them how important theSchoolis.notonlyroyou. butalsoto the Commonwealth. (reprimedi11 portfrom Compass, Vol l, .Vo. 13)

StrategytoManagetheProposed FV1992AppropriateOut Tollllcur$18,602tnThousandsolOallar1l

The Applicants - Past, Present and Future

Fall1960.H:istnw-<:utheaddroopsoverthe bi<X:hemlextthatrest�onhischinos He'sstudying enzymekinetics,buthis anention wanders tothe televistonscreen, whereJohn F. Kennedyand RichardM.Nixonaredebatinginblackandwhite. Thjsveterinarystudentisone of aclassof 56 men andtwowomen,theelite30percentchosenfromthe applicants.

fall1975.Thefreshman, one of54menand44 women,facedroughlyrwelve-to-onecompeuuonfor his�pot,andthisisthethirdtimeheapplied.While waitingforadmission,heearnedamaster'sin biochemistry, whicl1benowcoaststhrough.Hehas timetowatchWatergatecriminalswavefromprison. MargaretThatcher takesover theBritish Con�ervathePartyandrhecolorredcoversthe ...creen1nJows.

filii1990.Thetypicalstudentis ashe,notahe; MurphyBrownisarolemodelandthetvdebateis about colorizingLassie. She is studying biochem. trying todecipher gluc:oneogenesis,butsince she majoredinjournalism,shewondersifshecouldhave writtenthetextbookbetter.Sheisoneof 111 studems,represcntmg20percentofth�!3pplicants.

Malcolm"Mac''Keiter.directorofadm1ssions atPenn'sVeterinary School,says, "Weseek candidateswithabroadrangeofinterests-yetstilla deepinterest inanimals." increasinglyKeiter finds thatsomefemaleapplicantsmayexhibitwider imerestsandexperiencesthanmales."Forthemost rartthemenare tntheirearlylOsandarecoming strai!htfrom undergraduateorgraduateprograms, whilemanyofthewomenbadanothercareerbefore applying to veterinaryschool."

Thisyear'sclassts 72 percentfemale,compared to67percentlastyear."Womenhavebeengiventhe wrunginformation." Kdrer says. "'Theyhavebeen toldthe}can'tgerinto\:e£school,ortheycan'tdo theworkiftheydogetm,sotheydon'teventry. An additionalprobJem isthepersistingbeliefof counselors thatit isasdifficulttodayto get into veterinaryschoolasitwao;;10 to 15yearsago,andthe lackofcommunication between veterinatyschools andcounselorshasnothelpedmatters."

Thenwhatmake!>themapply,fmaJl}?"Theygo intoanotherfield-say.finance-buttheyhearthe opportunitiesforwomenare openingup,or they can't shakethewishto try vererinary school.They 'itillhaveanaggingdesire to work with animals."

Take AnnMacCormack-Byrd,28,alir�L-year student, forinstance. ApotiticaJ science majorat SntithCoUege,shethoughthumanmedicinelooked promisjng.Butafterworkingsummerst.nhospitals. sheswitchedtointernationalbanking. whichalso didn't fit.

"I kepttryingtofigureoutwhy1wasn'thappy, why I \\asn'tdoingwhatIreallywantedtodo.e\'en though 1 didn'tknowwhat Lhatwa�." �ys MacCormack-Byrd. "l kept comingbadeto medicine,thinkingmaybetherewasanoth�r"a�·to putittogether.1gotalot of ad\iceaboutcareers. Therewasasplitbetweenthepeoplewhosupporteda changeandthepeople whosaidyou shouldn't changeoutofwbatyou havedone,you shoulduse yourfirstmaster'sand notswitch to�omething entirelydifferent.••

Longapetowner andlheneighborhood caretakerforanimals,MacCormad:-Byrdwantedto lestthehypothesisthatvet�rinarymedicine:mightbe hercalling.Sheworkedeveningsandweekendsinan animalhospital. "If I wasgoingtotrya second career.Iwantedtobe:sure,''she!iays.Eventuallyshe Jert bankingandspentayeartaking addirional coursesandworkingatananimal hospitaland the ortheutAquanuminBOston.

ThecompetitionforaspotatPenn'sVeterinary School istough,fiercerinsome categories that orhe�.Of550applicants in 1990, Ill,orroughly oneout offive,matriculated. Atleast 62to64

membersofeachclas-sare Pennsylvania residents. Since Commonwealth residentscomposeonlya fourthof theapplicants,theircompetition is relativelylessstringent.OverhalfofallPennsylvania applicantsareoffered admission. Asthe Pennsylvanianumberhasdecreased,thenumberof those outside thestate hasincreased, anda more diverse classhasevolved.

Thescopeofthecompetitionhas changed dramaticallysincetheclassthaterueredin1960.the ear!testyearforwhichrecordsarereadilyavailable. On the admissionsgraph, thelineindicating matriculantscreepsupfrom 55in 1960to I10in 1978, then essentially llatlines. From 1960 through 1966, thelineshowing applications rises gradually. AstheSixtiesend,tltelinebecomessteep:Froman averageof200to350hopefuls,thenumbershootsup to850in 1972andoff-the-chanat 1,150 in'75. Applicationsplummetedtoaround500bytheendof thedecade.Matriculantsremainessentiallyconstant, at 109.

Mac Keiterattributes therapid mid-70sriseto theBabvBoomandtothecrunchofmenapplyingto vcterin�,medical.dentalandoptometryprograms toavoidVietNam.Often,hesays,studentshadto applyse>.eral timesbeforegetting accepted, some collectingmultipledegreeswhile waningfor space.

Since 1979lheapplicantpoolhasdeclined becauseof adecreasingeligiblepopulation and competitionfromotherfields.notabl)bu�mess,Ia\\., computersciencesandengineering.''Fewersludents areapplyingnow,"saysKeiter,''buttheystilltend tohavemoreeducationthanbeforethe boom, and theyaremoreidealistic."

IntheClassof1994,more studems(nine)graduated from CorneU University than anywhere else, followed by Pennsylvama State Univer!iity (six), and three each from AlbrishtandUrsinusCollegesand theUniversitiesofMi�higanandPennsyh·ania. lo all,thesestudentsrepresent 75collegesand univcn;ities.

Not surprisingly, biologyaccountsforhalfthe students•undergraduatemajors,andanimalscience 13percent.Exceptforthehandfulwho majoredin chemistryandzoology,studentswereequallylikely tohavefocusedonhistoryasanimalbehavior-in facttheycamefrom25majors.ChnstmeK.Smith. who majored in Russianlanguageand literature, admits there's"notie"betweenSlavic speechand Siberian huskies,bur she wouldn't tradeher liberal artsbackground. Fourteenfreshmen haveearned graduatedegrees:MA's,MS's.PhD'sandoneMBA. Asinglefactorlinks''eterinarystudents acrossthe decades.AsSmith63ys,"IalwayslovedammaJsweaUdid. Veterinarymedicine isagood career choice.••

Keiteraddsthatmodernveterinarymedicineisa diversifiedprofe..o;sionwithmanyoptions.Agraduate canpursuecompanionanimalorfoodanimal medicine,workwithaquaticanimals,hoes�. zoo a.n.imah, wildlife.laboratoryanimalsor havea careerinbiomedtcalresearchorregulatorymedicine.

•• And thisdiversitywillmake theprofession evenmoreattractivetotheyoungpeoplenowinhigh .school"anduniversities.Manyofthemha,·eagreat interest inhow wecan improvelifeontheplanet, howwecansave"anishingspeciesandhowwecan helppeopleandanjmalsandensureabeuerlife. Veterinarymedicinewillplay an important pan in thisandIamoptimisticchatourapplicationratewill remain steadyorevenincrease, even thoughthe number ofhighschoolor university graduateswill decreaseinthe-comingyears.WewillalsoseeaLarger numberofapplicantswho\\antlotakeup\Cterinary medicineasasecondcareer.notjustwomenbutalso men.Andasearningsofveterinarianscatchupwith otherfields,theprofessionwillbecomeincreasingly moreattractivetothosewh(}havealway�twaniedto workwith animals.''

--'SusanPerlofjj

StartLng Salaries

The Schoolconduc.ted a survey ofrecentgraduates (V'88,V'89,V'90). Amongthe question� was one about �tatting salaries Here are the figures:

19gs t989 1990

Small Animal Equine Pnc:titioners Pnc:Citioner�o $24,500$22,000 $27,000$24,000 $30,000$24,000

Food AnimaJ Practltioners $20,000 $25,000 S28.000

Tbe AVMA natloo�lde aHra.gefiguresror 1990 an: Small animaJ practitioners$26,800

EquinePractitionersS26.000

Food Animal PractitionersS27.000

It should be kept in mind thatin most practices raises will be granted afterSIX and 12 months Of employment. ln many cases these rais� are subsramfal.

Student Life

Thelifeofaveterinarystudentisstressful,new courseseveryeightweeks,exams,laboratories, city environment,andthehustleofcopingwitbdailylife.

Toeasetheburdenabit,anumberofpeopleare availabletostudentshereat Penn'sVeterinary School.TheOfficeofStudentAffairs,staffedby three,counsels,actsasaliaisonbetweenfacultyand administratorsandstudents,listenstosuggestionsby studentsandimplementsnewstudent-supportive programs.Itassistswiththemanagementofthe student-runbookstore, meetingsbetweenstudents andtheadministration,andtheStudentOovem.meDJ DinnerDance.ThisofficeaJsoorganizestheannual careerseminarandCommencemenr.andkeepsajob bookwheregraduatingclassmemberscanlocatejob openings.Afmancialcounselor/attorneyisretained toadvisegraduating seniorsduringemployment contractnegotiations.

Afull-timecurriculumcoordinatorisavailable toassistwithschedulingofcourses,arrangmgof electivecoursesatotherinstitutions,andscheduling clinicrotations.Toreducestudentstress,exam schedulesarenowstaggered.Initssecondyear,this hasproventobe avery successfulapproachasthe numberofre-examshasdeclineddrastically. Thedebtloadisaworrisomeproblemtomany students.Afinanciala1dadministratorisavailableto helpstudentscopewith theavalanche offorms, to assistindevelopingafinancialaidpackagestrategy andtomonitorthedebtloadandworkouta repaymentschedule. Loansandscholarshipsare administeredbythis office.The School isactively solicitingendowmentforscholarshipfunds,sofar14 dean'sscholarsarefundedfor partialtuition. Communicationsbetweenstudents.facultyand administrationare important.A facultystudent mentorprogram isinplaceandthedeanbas regularly scheduled..drop-in" hours for students. Studentslearnabout theseservicesfirst during orientation.Ontherecommendationofthestrategic planningcommitteeonstudentlife,odent.ationthis yearwaschangedfromatwo-dayimpersonal marathon oflectures onschoolpoliciestoasmall seminarformatwhichallowedthenewstudentsto meetfaculty,staffandupperclassstudentonamore informalbasis.Alumnitoobecameinvolvedinthls three-dayeffort.Andtoletthestudents"meet,.the ctty,sightseeingtripsviatrolley, subwayandbus werearranged.

st Annual Canine Symposiu•n

TheTwenty-firstAnnualSymposiumYouT Veterinarian and Your Dog washeldJanuary26,1991at theVeterinaryHospit11loftheUniversityofPennsylvania. Theprogram featured four speakersdiscussingavarietyoftopics,suchascommoneyeproblems in dogs, the Canine GeneticDiseaseInformation System, gastricdilation volvulus, sndthecanine blood bank st VHUP. Following aresummaries of thepresentations.

Gastric Dilation Volvulus Syndrome

GasTric dilation volvulussyndrome, orbloat, i� a life-threatening condition which can occur in all breeds of dogs. Dr. David Holt, lecturer in surgery, discussed the disease, its symptoms, andthecurrent treatment regimen.

It is not known why some dogs develop gastric dilation (distension of the stomach), butit is thought that these dogs are greedy eaters who swallow inordinate amounts ofair while eating, and that this air remains in the stomach. Theremay be a genetic predisposition to gastric dllation volvulus. Dr. GregoryAcland hereatPenn basbeen monitoringa colony of Irish setters for eye diseases and basfound agreater incidence of GDV in a line descending from one particular female. However, the inheritance pattern indicates that ir is not due to one gene, but rather to a number of genes and, perhaps, environmental factors.

In the past it had been thought that great amounts of food, followed by a large water intake, were the cause of dilation of the stomach. Another theory was that exercise after eating a large meal couJd cause the condition. However, in a study of 600 dogs, divided into groups, with different diets, large and small water intake and exercise aftereating, no significant differences in the occurrence of gastric dilation and volvulus in the various groups were found.

Dilatjon can occur alone or with volvulus. Volvulus can occur without dilation, but it is thought that dilation will only result in volvulus if the stomach is in an abnormal position prior to distention. Breeds affected are often largeand deep chested, although a retrospective epidemiological srudy of hospital cases here at Penn by Dr. Larry Glickman showed that there was not much bias toward the large breeds.

Thefirst symptoms of GDV owners may notice in their dog are anxiousnessand breathlessness. The animal may be restless, salivating and have a distended abdomen. The animal's condition can deteriorate rapidly as it goes into shock. Dr. Holt explained that poor perfusion is caused by compression of the portal vein and the caudal vena cava by the distended stomach. The reduction in blood flow causesa decreasein cardiac outputof 64 percent, a decrease in blood pressure by 48 percent and poor tissue perfusion. Poor perfusion and oxygen delivery to the heart muscle result in arrhythmias which may develop up to six to 24hours after onset ofGDV. Another contributing factor to arrhythmias are circulatory cardioactive substances which further compromise the labile state of the heart. The reduction in blood flow also affects the liver, spleen and kidneys and can cause disseminated intravascularcoagulation (D.LC.), a life-threatening complication. The stomach itself is severely compromised in GDV as its bloodflow is decreased

up to 80 percent, resulting in death of tissue. In severe cases the stomach can rupture, causing peritonitis.

A dog with gastric dilation needs to be seen by a veterinarian very quickly. Dr. Holt explained that the treatment regimen has changed over the last few years. In the past, animals with GDV were taken straighttosurgeryfordecompressionofthe stomach and correction of the volvulus. The successrate was about 50 percent.

Now the first step is to prevent or reverse the circulatory collapse by administering fluids intravenouslyto stabilize the animal. Antibioticsare sometimes given because of the possibility of infection. Radiographs are taken to determineif the stomach has rotated. The stomach is decompressed onlyafter the circulatory systembasbeen stabilized.

Decompression is accomplished by passing a tube into the stomach or, ifthat is not possible. by using a large gauge needle to let the air escape. Throughout these procedures the dog is carefully monitored for vital signs and bloodvalues as well as cardiac arrhythmias.

If volvulus has occurred, surgery is necessary to reposition thestomach. Here the surgeon oftenfinds unpleasaru surprises such as dead stomach tissue, necessitating partial removal of the organ. Sometimes splenic vessels are thrombosed and the spleen needsto be removed. To preventa recurrence of volvulus, the stomach is upex.ied'-' to tbe abdominal wall. A tube is placed in the stomach, exiting through the abdominal wall. Stitches are placed at the juncture of the tube, stomach and abdominal wall. As the animal heals the sromach wall and the abdominal wallform adhesions, holding thestomachfirmly inplace.Thisprocedure willnot prevent subsequent dilation, but it will prevent volvulus. The tuberemains in place for ten days and is then removed. The wound heals quickly. If dogs suffer from frequent gastric dilation, such surgery should be considered to prevent volvulus.

In a dog lying on its back:

roeat on their own. When the patients rerum home, they receive their regular diet, though frequentsmall meals are recommended.

Dr. Holt feels that a dog's best chance of survivinggastric dilation volvulus is early recognition of the problem and aggressive use of rehydration prior to surgery.

He recommends that greedy eaters be fedsmall portions and that measures are taken to slow down the gulping of food. He advised owners to bealertto the firstsignsof the diseaseand to gettheseanimals to the veterinarian quickly because delays in seeking veterinary care mean more severe complications of GOV.

Control of Genetic Disease in Purebred Dogs: Role of the Canine Genetic Disease Information System

Dr. Donald F. Patlerson, Charlotte Newton SheppardProfessor of Medicine and Chief, Section of Medical Genetics, together with Ms. Patricia Green of his staff, discussed the Canine Genetic Disease Information System (CGDlS), a unique computerized reference program containing comprehensive information on canine genetic diseases. The CGD1S is designed to assist veterinarians and breedersin the quest to accurately diagnoseandreducethe incidence of genetic disease in dogs. The project is supponed by the American Kennel Club.

Advances in veterinary meclicine during the last 30 years have greatly decreased the morbidity and mortality rates in dogs from diseases caused by infectious agents, malnutrition and parasites. There is now an increased awarenessof disorders caused by congenital malformations, growth related deformities, metabolic defects, disorders of the immune system and cancer. all of which have importantgenetic components. While therepresently is no cure for most genetic disease, most can be prevented, or at least reduced in incidence, through selective breeding practices. It is for the recognition of inherited diseases and the development of such breeding strategies that the CGDlS is important.

the picture a normal stomach presents tbe picture a volvulus presents.

After surgery the patient is moved to the Intensive CareUnit for abouttwo to three days. The first 24 hours can be critical as arrhythmias and D.l.C. may develop. The patient is connected to bean and blood pressure monitors and receives intravenous fluids. Transfusionof blood mayalso be required. Rehydration and stabilization prior to surgery have reduced the mortalityrateto about 15 percent. Some dogs may develop pneumonia as a result of having aspirated stomach fluids. They are treated with antibiotics, nebulization and coupage. These dogs often require a longerstayin lCU. Solid food isgraduallyreintroduced once the dogsare able

Dr. Patterson explained that mammalian species have about 50,000 genes and the function of most geneo is the production of a specific protein. lf a disruptionio the gene occurs, disease mayresult. ln many diseases environmental factors play an importantrole in the severity ofthe disease. Alone end of the scale are diseases that cause mortality mainly due to defective genes whileat the otherend are diseases caused mainly by environmentalfactors such as viruses. However, even here genes enter the picture as some animals, due to their geneticmakeup,aremore resistantto viralinfections than others. For example, it bas been shown that Doberman pinschersand Rotlweilers are more severely affected by parvovirus infections than other breeds; this susceptibility has a genetic basis.

By 1988 researchers had recognized 281 generic diseases inthe dog, since then ten to 12 new canine genetic dheases are described annually. The number now stands at over 300. This does not mean thatnew genetic diseases are constantly developing. Rather, discovery of additional genetic diseases is due to increased sophistication of veterinary medicine and improved diagnostic tests.

Genetic diseases may involve any of the body

systems. AI tllis timethelargest group ofdiseases 1dentified IS that ofbonesandjomts, followed by diseases orthe neuro-muscularsystem. Thl) is understandableassuchdisordersareeasiertorecogntzelhan a genetic defect of metabolism, for example.

Tite de\'elopment of an effective program to reduce the frequency ofgenetic diseases requires three ingredients:

I.Knowledgeoftheclinica1signs,laboratory tests,andpathologycharacteriStiCSOfthe<lisease,

2.Knowledgeofthe mode of inheritance.

3. A program to prevent affected animals and carriers ofthe mutant genes from breeding.

lci�herethattheCODISbecomesinvaluable.II is acentral repository for all known canine Eenetic diseasesanditwilJbecontinua1Jyupdated. Thedata basecontains not only theinformation on breeds affected, but such informauon as symptoms or clinical signs, age ofonset, primaryand �econdary body systems affected, available diagnostic tests, l'atholog)' findings, individualsor institution� with specialexpertise{orlhedisease.geneticsandmodeor inheritance, recommended methods ofcontrol, and published literature (several 1,000 references). The CGDISdoesnotcontainspecificdogs,ped1greesor breeden.• names.Itdoes,however.coverallknown breeds ofdogs, ranging from rare breeds not even seen in this country to the AKCrecognized breeds.

Thesystemi.e; microcomputerbasedand,.,.;urun on the recent IBM compatible systems available 10 maoyoft1�andhomes.Theinformationinthedata baseisassembledfrompublishedliteratureandfrom veterinaryinstitutions.Atthispoint informationon over200d1seases has beenentered into thesystem. Eachdiseaseisrevtcwed by the members ofthe School'sSectiOnofMedicalGeneticsdunngweekly meetings.thepertinentfacts.descriptiveparagraphs and reference tists ar�assembled This material il> editedrepeatedlybetoreitisenteredimothecomputerinatime--consumingprocess Dr. Pattersonhopes toadd Information from imJiviuuuJb1ceddub geneticscomminees tothe databa!<eat a laterdate. Whilesuch mformation would not always have scientificverification, it could serve as "an early warning system'' ro veterinanans and breeders.

Thesystem can !Search thedata base for information ma variety ofways. One can ask It for diseases .Jffecung aspecific breed and then obtain information oneach individual disease. Or one can entera disease and then ask which breed\nre affected ThesystemalsopermitsasearcJtbydisease characteristics. It can also be u�ed toobtam a completehst ofallgenetic disea�esaffectmg a particularbreed.Dr.Pauersonpointedoutthatthis systemwtllbeveryusefultovetennariansandthatit willenablea\ietennariantohandaclientaprint-out mlaylanguagepro\idmg information about the specificdiseases found in any breed It will also enabletheveterinariantobetteradviseclientsonbow toreducetheincidenceofaspecificdisorderthrough �elect.J\ie breeding.

TheCGDISwillpavethewayforacomprehensivecenification program for breeding stock asalJ theinfonnation about canine geneticdiseas� will finall)beeasytoaccess.And,asthesystemwiiJbe continuallyupdated,itwiUprovideveterinarian�and breeders with the most up-to-dateinformation

TheCGDIS will be field testedlaterthis year andwinbeavailableforpurchasesometimein 1992.

Common Eye Problems Important to Dog Owners and Breeders

Dr. Stephen Gross, a boardcertified ophthalmologisl,beganhispresentationbystressing the importance of the Canine Eye Registry Foundation (CERF) which oversees lh.e canine eye cenificationprogram.Dogsshouldbee�amined for eyederects at age 1 112 years and then annually thereafter. The eyeexam isperformed by a board certified ophthalmologist, usually duringeye clinics sponsoredbydogclubs.Unfortunatelymanyofthe inheritedeyediseases mdogs are apparent at different ages,some forms orcataracts may be evident veryearl)' while others cannot bedetected untiJtheanimalisfourorfheyearsold. Thesameis trueforprogressiveretinalatrophy,thus,Dr.Gross stressed, conscientious breeders havetheseexams performed until dogs reach the age of eight to ten years, depending on the breed.

Dr. Gross explained tbal the anatomy ofthe dog'se}eissimilartothatofthehumaneye,though thelensISthreetimesaslargeandtbedoghasathird eyelid. The dog also hasa ret1ectivesurface inthe backoftheeye,thetapetum,whichiscommoninall specieswithhigh}}developednight\rision.Tbeouter surfaceoftheeyeisthecornea;thenextlayeri�the fluid-filledameriorchamber.thencomesthelens,a clear crystal-like structure which focusesthe image thedogsee�.mu�hh!..e10acamera:followedb}tbe viueou�.agel-likesubstance,andrheretina,alayer ofnervous tissue at the back of the eye. Theoptic nerve transmits the Image from the retina to rbe brain.Dogs.unlikepeople.canpullbacktheeyeifit tspainful, the third eyelid then slides into place, protectingit.

The parts oftheeyeare delicateand microsurgery is perlormed with special instruments and a biomicroscope. Stitchesare numerousand tiny.Dr.Grossstressedtheimponanceofseekingan experienced specialist forany kind ofcanineeye surgery.

Th( li�t eyeproblemdiscussedwas the dermo1d,adevelopmentaldeft.-<:t Atinypiec.:eofsk.in grows on the cornea. Although it does not impair vision, it often causes irri£ation because it contains hair follicles. It iseas'ilyrepaired by surgery. Dr. Gross feels that dogs which have dermoids should not be bred.

Faulty eyelids can cause quite a few problems fordogs. Quite a number of breeds, particularly brachycephalic ones, have rather large, protruding eyes, making the organ prone to injury. In extreme casestheeyecanpopoutofitssocketwhentheupper eyelid shde!> behind tbe eye. This injury can be surgically repaired, however, vi�>ion is often lost in theeyebecausetheopticalnervehasbeendamaged Surgerytocorrecttoolargeaneyeopeninginvolves stitchingtogethertheeyelidsatthecomersortbeeye. Eyelashes usuallygrow on the skin side ofthe eyelid.Buttheycangrowrightattheedge.rubbing againsttheeyeandcausingirritation.Theycanalso grow on the inside of theeyelid, causing great discomfort and, in some cases, ulceration of the cornea.Sometimesadogcanhavenormaleyelashes andthenasecondrow1nsidethelid.AUthesedefects mustbesurgicallycorrectedtopreventdamagetothe eyeand to make the dogcomfortable. The surgeon removes the follicles by microsurgery to prevent regrowtl1 of the hair.

Entropionisanotherdisorderwherehaircauses discomfort,thoughitistheruraroundtheeyewhich irritates.Theeyelidsrollinandtherurrubsagainst theeye. Th1s is quite common 10 breeds that are heavily wrinkled, particular!)·on the forehead. In extremecases,thedisorderisevidentasearlyas12to 14daysofage. In young pupstheeyelids can be tacked up togive the dog time togrow. Dr. Gross explainedthatthecorrectivemicrosurgery.involving a complete restructuringoftheeyelids, is normally doneat four to siX months ofage, but in extreme casesitcanbeperformedearlier. Lfnottreated,the constant irritationcauses ulcerationofthe cornea and great discomfon.

CoroesJ ulcer

Cataracts are not painful, but they cause impairmentorlossofvision.Acataractisdefinedas anyopacityonthelens.Theyarecommoninmany bree.dsandaremostlyinherited.thoughthemodeof Inheritanceisnotclearlyunderstoodinmanybreeds. Cataracts also can becaused bytrauma, and, in youngpuppies,bymilkreplacer.Dr.Grossexplained thatthelensdevelopsinlayersastheanimalgrows, thus the location ofa cataract provides 1mponan1 cluestoitsnature.Cataractswhichdevelopedinthe fetushaveadifferentlocationthanthosedeveloping at a later age. Cataractsrangem size. density and rateofgrowthandmustbeobseC\iedoveraperiodof months.Cataract:,canbesurgicallyremoved,though thisdependsonthepatient. JrtheanimalISoldand not veryactive, it isoften best to not perform surgery. partkuJarly if the cataracts had a gradual onset and the animal hasadjUllt� to Hs hrruted vision. The pupil can be dilated with medication to enlarge the dog's limited vision. Dr. Gross stressed thatdog�cangetalongwell"'1thseeingJUStfromone eyeor\\ithlimitedvision.UsualI}cataractsurgeryis performed oncethesecondeye becomes affected.

Cataractsurgerytnthedogismorecomplicated thanin humansbecauseofthelargersizeofthelens and the fullanesthesta required. Also, dogs' eyes react to �urgerywith greaterscarringthan human eyes.Thereare<lifferenttechniquesemployedbythe surgeon. Theentire lens can be removed ora techniquecalledphacoemulsificationcanbeused A tiny inc1sion ismadethrough the cornea and an ultrasoundprobe1sinsertedandusedtoshatterthe cataract.Thepiecesareremovedandtheincisionis closed.However,thistechniquedoesn'tworkrorall types ofcat.aracts.

Dr.GrossexplainedthatadogcanseeWithouta lens,thoughitisno1abletoseesmallthings,bUlit can observe a room and largeobjects. Healso mentioned that ophthalmologists have begun Lo implant lenses, but thistreatment is quitecostly. A softcontactlenstsusedinthetreatmentofrecurrent curnealab1asions,a condition in older dogs where spontaneousabrasionsofthecorneadevelop.These areveryslowtoheatandquitepainful.Thecontact lens racilitates healingand makes the eye more comfonable.

Cornealabrasionscanalsobecausedbylackof Lears.ThisisoftenmanifestedbyaneyeWithared film and copious amountsofmucous. lt is thought lh.at tbelack oftears is dueto an inappropriate immuneattackontheLearglands.Eacheyehastwo suchglands,oneisquiteramiliartodogownersasit can pop up from its placebehind thethird eyelid gh;ngtheappearanceof"cherryeye." lnthepast. surgeons removed thegland. but now it ISstitched back into place to preservethe teargland. Lack of tearsisLteatedwithaspeciallyformulatedointment anddrops.

During thequestion and answer penod Dr. Grossexplainedthatcholesterolorlipiddepositsin theeyearenotcataractsandthattheyaredue10past injury,drynessorscarring.Hesaidthattheydonot severelyimpairvision..Hementionedthatoneshould cbeck thedog's eyes frequentlyand ifsudden squintingordischargeoccurs,aveterinarianshould beconsulted.Thestatementthatanysurg1calre-pair wouJd render a dogineligible for AKC shows wa:, alsoaddressed.Dr.Grossstressedthattheserepairs arenecessary for thecomfon and health ofthe animalandlhalitisuptotheowner'sethicswbelber or not the dogwill be shown.

Transfusion Medicine and the Blood Bank at VHUP

Transfusionmedicineisarelativelynewfieldin veterinary medicine and blood transfusions are becoming an increasingly important treatment modality.Theyarethenumberone:tissuetransplant procedurem humans and animals. Donna Oakley, VJIUP head nurse and blood bank coordinator, provided an overview of transfusion medicine and che canine blood donor program at the Veterinary Hospual of the University of Pennsylvania.

She mentioned that the first reponed canine bloodtransrusionwasperformedinthelate 1800sby surgicallyattachingthearteryofonedogtothevein ofanother. Today blood is transfused through IV catheters and, in most cases, whole blood is not admmistered, just the required specific components of blood.

Blood iscomposed of a liquid portion, the plasma,andacellularportionconsistingofdjfferenr celltypes: redbloodcellscarryingoxygen: whitecells servingasadefensemechan1smproducingantibodies and locating, engulfing, and destroying foreign material; platelets with strong adhesive properties facilitating clotting. Plasma consists ofwater, salt andproteins(albumin,clottingfactors,etc.).Aunit ofblood can be separated imo its different components, allowing treatment of specificdiseases with specific blood products.

For example, a red cell transfusion may be needeu if an animal has become anemicdue to Babesracanrs{a protozoa) infectton or from heavy flea mfestation. Red cells are also needed for the criSIS management of hemolytiC anemia before the dog can receive drugs to correct its over-reactive immunesystem.Clottingfactorsareadministeredif an animal has a bleeding episodeduelo von Willcbrand's disease. By using these specific components, exposure to volumeoverload and the inc1dence of transfusionreactsonscan be greatly reduced.

Blood for any tTansfusion lS crossmatched to determine whether donor and recipient are compaL.ible histhoughtthatdo�haveasmanyas 13 different blood groups, however. a� Ms. Oakley poin1ed out, itispossiblethat manymoregroupsY.'ill bediscoveredasthestudyofcaninebloodcontinues. Threegroupscausethemostseverereactionsdueto incompatibility. Two types of transfusion reactions

Roger Caras Honored

Collectingbloodfrom I& donor canoccur:immunemediatedreactionwherethebody destroy!>redceJlsbecauseofantibodiel.presentinthe recipient;andnon-immunemediatedreactionwhich occurswherlthebloodproductsbeingtransfusedare defective, due to an improperly collected, stored or admuustered product. Bothreactionsnresevereand canoccurforuptolhreeweeksafterthetransfusion, requiring close monitoring of transfusion patients. AtVHUPallbloodandbloodproductsarestoredin state-of-the-anrefrigeratorsandfreezersdesignedto keeptherequiredtemperaturesatalltimes.Allblood transfused here is passed throug.h special filters to remove clots or other debris.

Ms. Oakley briefly mentioned some blood transfusionalternativesreducingadversetransfusion reactions:concentrated hemoglobintransfusionora hormonetreatmentthatstimulatesproductionofred bloodcells; preoperativeautologousdonation where, priortoelectivesurgery, theanimaldonatesitsown blood which is available later if needed� acute normovolemic hemodilution for long procedures wherebloodlossisanticipated Thislastnlternative involvesremovingmultiple unitsofbloodwhichare replaced by intravenous Ou_ids tO dilute the blood prior 10 surgery. Post-operatively. the patient is transfusedwithitsownblood.eJsminatingthechance of transfusion reaction [0 a foreign donor.

VHUP performs between threeand siJC transfusionsdaily.Bloodisalwaysneededandrhree years ago a program was initiated where students,

faculryand staff brought in their dogs to donate blood.Soonitwasrealizedthat theseanimalscould notmeetthedemand,andDonnaOakleyreachedout todogclubsandbreedersinthetri-statearea. Today abnosL 500 dogs areenrolled in VHUP's canine blooddonorprogram.Theseammalsarebroughtto VHUPregularlytogivebloodtohelpsickpatients. Caninedonorsmustbeatleastoneyearofage and �houJd not be older than 10 years. They must weigh at least 50 pounds and cannot be on medicationotherthanheart\\or-mpreventive. When they come to VHUP, a complete blood count and heartworm test are performed to ensure adequate health c;tatus.Thecollectionprocesstakesabout five minutes. Theanimalis placedonit'lsideonatable. Theownerisusuallypresent,helpingtokeepthedog inposition. Bloodiscollectedfrom thejugularvein and removed by means of a pump to speed up the process.AccordingtoMs.OaJ.Iey,dogsdon'tmind the collt\;tion process, though )Orne get a bit smpatient for having to remam still for the five minutes.

After 1he pint bas been collected, the dogis taken fromthetable,offeredalight mealandwater. ItaJsoreceivesablooddonorIDcardandtheowner isiostru�.:ted 10limitexercisefor24 hours.Sixweeks later the dog t.'all again donate blood.

Theprogramat Peon's VeterinarySchoolisthe largest m the country. Ms. Oakley hopes that soon owner) and their dogs wiU not need to travel to VHUPastheSchoolwinbeobtainingamobileunit toserveasabloodcoUecungstationonwheels. ltwill beequipped wtth an exam table, cooling unit. mkrohcrnatocrit centrifuge. hemoglobsnometer, gramscale,andotherbloodcollecungandprocessing equtpmenl. The mobile blood unit will enable VHUP's transfusion medicinespecialiststo visit large breedmg kennels and kennel club-organized blood drives in outlying areas where blood can be collected from canine donors, making thedonation of blood much moreconvenieiii for dogsand their owners.

Theacquisitionofthevehtcleand1tsequipment ismadepo\siblethroughthegenerousdonationsof the Bernice Barbour Foundation, Dr. Daniel Bleicher, Officer Dan BucJJ.e), Chester Valley Kennel Club, Delaware Valley German Shepherd Dog Club. Devon Dog Show Association, Mr. and Mrs. Peter Nero, Penn Ridge Kennel Club, Peon Treaty Kennel Club, Southern New Jersey German Shepherd Dog Club, and Mrs. Ferdinand White.

TheMarylandVetennaryMedicalSocietyhelda "roast" for Dr. Roger A. C.aral. in Baltimore in October. At theend of 1he evening Dr. Caras was laudedforhismanycontributionstowildlife,animal welfare, andtheveterinaryprofe.c;sionatlarge.Dean AndrewspresentedtheSchool'sCentennial Medal£0 Dr.Caras. Followingislhelaudation,composedby Dr. Donald A. Abt, that was read during the presentation:

..Di�tinguishedspoke1.manforandchampionof aJI aruma! life, large and small. domesuc or wild. traveling the worldoverto share your love and dc�<otionforanimalswithyourfellowhumanbeings through authorship of b1ghly respected and wsdely readboo.,_s andmagazinearticles; notableradioand televi&ion presenter; tireless personal contributor of talent, time and energy to a legion ofworlhy organizationsdedicatedtolhewellbeingofanimals; andwisecounselortoLboseinneed. Worldtraveler fromtheplainsofAfricatotheislandsofGreece,to the Far East. to Prince William Sound and even ro the South Pole, to idenllfy but a few of the sites whereyourconcern for animalsand society has drawn you.

From each location, you brought back a ne\\i andvitalappreciationforand understandingofthe fragile balancewithin which our non-human neighborslive.Youreloquentvoicethen focusedour allention, withclarityand.respect,ontheneedsand

phght of those deservjngour concern. You have brought constructive awareness ofour responsibililies to all segments ofour <>ociety.

In particular, you baveserved the School of Veterinary Medicine at the University of Pennsylvaniawithgreatdistinctionbothasamember of its Board of Overseers and as a deeply involved participatorymemberiftheadJUnctivefacuJt).Asan Overseer. you have provided your fello\\ Board mcmbe� with the interactions of animals and mankind thereby facilitating enlightened decisions cruc1al to the advancement of the School. As a teacher, you have paved theway foressential broadeningofour students' horizons. Your course dealing with the diverse interaCLIOnc; of veterinary medicineandsocierybecameabenchmarklOwltich others aspired as it led our students into uncharted waters. The ever-increasing requests for enrollment were a [estamem to the value of your contribution and sagmfied the foretltoug.ht you exhibited by seeking the opportuniry to present such acourse. What was once unonhodox has now become common place through your concerns and gifl of sharing. To share oneself through the education of our youth is truly a noble gift

ln recognition ofyourextensivecontributionsto ourSchooland theveterinaryprofessionatlarge.we arc honored to present you this, the Centennial Medal of the School of Veterinary Medicine."

Laboratory Animal Medicine Residency Program

fn June of 1990 three veterinarians graduated from Penn after completing a postdoctoral training 1esideocyinlaboratoryanimalmedicine.Theywere thefirsttocompletethelaboratoryanimalmedicine residency program, established in 1987 at Penn's School ofVeterinaryMedicine. his the only such program academically based in a veterinary school, andofferspostdoctoraltraininginlaboratoryanimal medicine through the Veterinary School aud the Office of Univer�ity Laboratory Animal Resources. The program is under the diret.."'tion of Dr. Harry Romtiarek.professoroflaboratoryanimalmedicine and Director, Office of University Laboratory AnimalResources. ''Weofferathree-yearresidency inlaboratoryanimalmedicine.''saidDr Rozmiarek. ..Wewanttograduatecompetentlaboratoryanimal \tterinariansandresearchscientists.Theiracademic homeistheveterinaryschoolbuttheclinicaltraining takes place there and at the three other Schools on campuslhat hottse animals. The residentsgain additional dinkal experience byseeing cases at the Philadelphia Zoo, other research institutiom in Philadelphia, and at private industi) animal laboratories. They work with a wide variety or species, ranging from insects and ftsh to large: mammals.''

IIisestimatedthatmortthan20millionanimals are housed in research laboratories in the USA. By tar the most arc roden.ts.However, laboratory animalsincludeamultitudeofspecies,rangingfrom &nolluskstoprimates,eachrequjringspecificcareto rcmamhealthyandcontent. Whileanimalshavebeen anirnponantpanofmedicalresearchforcenturies, regulations coveringtheircare we.renot enacted in truscountry until 1966. Specialized laboratory animal medicine rraining for veterinarians bec.;arne formalized nine years earlier, in 1957, with the c�ttablisbment of the American College of l.aboratory Animal Medicine. Prior to the �pec1alized veterinary medical courses, the topic of laboratoryanimalswascoveredinlaboratoryanimal J�cience, not n�essarily taught by veterinannns.

Or. Rozrniarek explained that a laboratory animal medicine veterinarian deals not onh wirh individuals but with populauons ofcolonies. "Our practice is a preventive one, we try to keep disease out ofthe colonies. For example, we are trying to eliminate all rodent viruses from campus." The residentsand laboratory animal medicine veterinarians see their patients in thecolonies, very muchlikeclinicians. • 'Therearetliseasesthatareof uniquecon�eminlaboratoryanimals,suchasrodent viruses.Andbecausemanyanimalsarekepttogether 10 one area, the transmission of disease within a colonyisal\\aysorforemostconcern."Theammal facilitiesinclud�isolationwardstopreventspreadof infectious diseases. At hand are also diagnostic facilities, such as laboratories for tests as well as pathology laboratories, for the quick identification ordisease.

Theresidentstrainiotheclinicalsettingandtake courses in biostatistics, geneti�. immunology, radiation biophysics, and research method\. ln addition,theyattendweeklyseminarsonlaboratory animal pathology, biology and diseases, uses of laboratoryanimals,andlabo1atoryanimal medicine. Clinicalandpathologyroundsareheldeveryweek.A reo;ident may specialize in an> aspect of laboratory arHmalmedicml!;nutritionisan example, itisoffered hereat Penn. Each resident must be the primary Investigator for an independent research project involving an1mals: a scientific paper must be preparedandacceptedforpublicationbyarefereed jOUrnal.

BesidesaUaspectsofmedicalcareforlaboratory animals, the residents' trai1ting covers proper socialization of these animals. enrichment of their environment through lighting, play equipment, and

interaction with humans. These are especially important to keep cats, dogs, and primates content and occupied.

The administrative aspects of the spec1alty are also covered. Residents arc familiarized with institutionaJ,state,andfederalregulationsgovl!rning laboratoryanimals.Theylearntodesignaresearch project from the initial proposal to the grant application process to shepherding it through the U111versicy regulations to carrying out and monitoringthework, inshort,Lheyareexposedtoall aspects oflaboratory animal medicine, be they medical or administrative. Once the residency is completed, a board exam can be taken to become board certified in laboratory animal medicine.

Inadditiontoacorecourseinlaboratoryanimal medicinetakenbyallveterinarystudents,laboratory ammal medicme courses arealso offered as an elective toJunior and senior veterinary <otudents. "Last year wehad 35 students taking the course,·· saidOr.Roznuarek "Thereisagreatdealofinterest inthesubjectandagreatneedforqualifiedpeople.''

Whilethesubjectofanimaluseinresearchisa controversial one, the post graduate uaining in the specialty, and the courses offered to veterinary students, ensure that specially trained veterinarians takeanactiveroleinthecareoftheseanimals.Asthe graduatesoftheresidencyprogram arefamiliarwith the medical requm:ments and regulatory and administrative concerns, animal researchprojects can be better designed and monitored, keeping the wellbeing andcomfort of rhe animals foremost.

Thepostdoctoralresidencyinlaboratoryanimal medicineisopentoapplicantsholdingaVM0/0VM degTeeorequivalent Forfurtherinformationabout the program. please conract:

Or. Harry Rozmiarek Professor of Laboratory Animal Medicine Director, Office of University Laboratory Animal Resources

Univer�ity of Pennsylvania

tOO Blockley Hall

Philadelphia, PA 19104·6021

Dr. Stubbs dies

Dr. Evan Lee Stubbs, a pioneer researcher in avianpathology.diedJan. 3, 1991 aftercelebrating his 101st birthday at his home in Kennett Square, PA. Or. Stubbo; graduated from the University of PcnnsylvamaSchoolofVeterinaryMedicinein 191t wbeo veterinary medicine in the United States was stiU an emerr.lng profession; the primary patients werehorse!>,cowsandotherLivestock,andveterinary rc.l)earchen; were :o>carce.

Dr. Stubb.\ opened a country practice at his father'sfarmnearOxford, PAandmadefarmcalls for more than two years by horse and carriage. ln 1913 he accepted a position as veterinarian at lhe State Farm, located in Marple Township, PA. This fann, operated by the Pennsylvania Bureau of A.nimal Industry, produced anti-hog cholera serum "hich was supplied free or charge to vetcrinariam. Or. Stubbs was also on call to visit sites of hog-cholera outbreaks and was available for other diagnostic assistance.

TbeState Farm was clor.ed in 1919 and Or. Stubbs was transferred to the State Laboratory, locatedatPenn'sVeterinarySchoolinPhiladelphia. Herehewasresponsibleforconductingavarietyof diagnostic tests. primarily for diseases 10 hvestock. AtthattimeOr.StubbsbecameintereStedinpoultry diseases. a·field thenneglected by theveterinary profession. Hewasoneofthefirstresearcher!.inthe Uruted States to study avian diseases. He identified rhefirstcaseoffowlplagueintheUnitedState:.and conducted research on avian influenza. Dr. Stubbs also studied avian leukOSIS and strain 13 sarcoma virus experimentally. By 1927 he bad published 15 scientificpapersonpoultrydiseasesandhadtnidated aspecialpostgraduatecourseonpoultrydiseasesfor veterinarians.

In 1927 the State Laboratory was moved to

Photograph

Harrisburg. Or. Stubbs resigned liis position as directorandacceptedateachingappointmentatthe SchoolofVeterinaryMedicine.Heplayedaleading role in the establishment ofa laboratory of clinical palhologyartheSchoolandwasinstrumenLa.linthe formation of the School of Animal Pathology, a collaborativeeffortofPenn'sveterinaryandmedical schools.

ln 1928 he became assistant professor of veterinarypathologyattheSchoolanddevelopeda clinical pathology course and courses m poultry pathologyforveterinarystudents. Heplayedavital role m the establishmem of a veterinary pathology graduate program at the University. In 1930 Dr. Stubbswaspromotedtoprofessorofpathologyand headoftbenewlycreateddepartmentofpathologyin the Veterinary School.

Duringhi:.longcareerOr.Stubbspublished 161 scientificarticlesandattendedfourWorldVeterinary CongressesandeightWorld PoultryCongress�.He presentedpaper'>atanumberofthesemeetingsand became au internationally known and respected poultry pathologist.

Dr.Stubbswasoneofthefoundingmembersof theAmericanCollegeofVeterinaryPathologists.He served as its president in 1960.

Dr.Stubbsretiredthatsameyear. lnSeptember 1988 theSchooldedJcatedtheStubbsLaboratoryin his honor at the School's New Bolton Center campus. This building is used for research with infectious organisms, primarily of poultry.

On the occasion of his IOOth birthday celebrationin 1990 Dr.Stubbsentertainedhisguests with vivid accounts ofthe early days or the School thussupplementingmaterialhehadpubbshed10the School's first official history book in the 1930s.

At the time of his death Dr. Stubbs held the position ofemeritus profe�sor of pathology at the Universit} of Pennsylvania School of Veterinary Medicine. Dr. Stubbs is survived by Ruth Stubbs Denlinger. Bethesda, MD, his daughter, and by his sister Elma Stubbs Mason, Oxford, PA, and seven nieces and nephews.

Dentistry Program Expanded

Thesmallanimaldentistryprogramexpanded1n 1990-1991. Asecondveterinarydentalre<iidem.Dr. PaulOrsini,wasappointed. Dr.Orsiniwillcontinue to work with somelarge:animal dentistry-ora! �urgerycase�atNewBoltonCemerperiodically.Dr. Phillippe Henoet, a visiting research fellO\\, is working on a projec1 to evaluate metrontdazolespiramycin as an antibacterial combination for oral diseases in dogs. Ms. Bonnie Flax. RDH wa<> appointed as staff hygienist at VHUP and research technician in veterinary dentistry, replacing M!). MarshaVenner.Otherneworcontinuingveterinary dental research projects include multi-hospital studiesoftheepidemiologyororalandperiodontal diseases in dogs and cats, and causation of 'neck lesions' in cats.

OR. EVAN L. STUBBS (Class of 1911).

from the 1930s.

DonnaOal.ley,VHUPbeadnurse/wardbandblood bankcoordmator,receivedthe 1990AnnualHumanitarianAwardIromthePennsylvaniaFederauonof DogClubsforherworkwiththeout-palienlVHUP Blood Donor Program.

Sally Powell.supervisorofnursinginVHUPemergencyservice. and Nancy Sbaffran. head nurse VHUP lCU. havebeen invited to represent Penn's VeterinarySchool at the 1992 International VetermaryEmergenc}andCriticalCareSocietymeeting. Chosenas "super techs," theywLIJ beamong only eight people in the nationinvitedto participate.

Or. Erkrulleners, assistant professorofsurgery, received agrant from the Grayson/Jockey Club Foundat1011tostudyidiopathiclaryngealhemiplegia {roaring). Dr. TuUeners hopes to develop a noninvasive surgical technique to treat the problem.

Dr. Jerrrey A. Wortman, V'69, associateprofessor ofradiolog}.waselet.'tedpresidenroftheAmerican College of Veterinary Radiolog}.

Dr. RichardSquires,lecrurerinmedicine,successfully defended hts Ph.D. thesis, entitled ''Characterization ofendogenousretroviraJelements in canine DNA."

Or. Chari� D. Newton, professor oforthopedic c;urgery,hasbeenelectedtothegovemmgboardofLhe Univcr$ity'c; L1ndbackSociety.

The PenllS}lvania VeterinaryMedical Association awarded Dr. Emes1 J. Witte. V'42. the Dbtinguished VesennaryPublicServiceAwardforhh'iCJ'Viceaschief, VeterinaryPubhcHealthSectionanddirector,Division ofAcuteInfectiousDiseases,PennsylvaniaDepartment of Health from 1952 to 1988.

Dr. Mary Dcllafera, V'79, has been appomted resea1ch assistant professorin laboratory animal medicine. Dr. H. Mark Saunders. V'81, has been appointed assistant professor or radiology. Dr. Joy Weiru.lein. \ ..83, has beenappointedassistantprofessoroforthopedic surgery

Dr. 'lisbi Dbupa. resident inemergencymedicine and critical care, rtteived thecerttficate in smaU animalcardiology(RCVS).

Dr. Oa"id Diefenderfer, V'81, lecturerinorthopedic surgery, received the ·•warm Fuzzy Award," presented annually by the Philadelphia area veterinary associations for exceUent serviceto referringvetermanans and their diems.

Dr. Corinne R. Sweene). assistant professor of mcdic1ne,andOr.JoanC. Hendricks, V'79, assil>tantprofessorofmedicine,wereelectedtotheboard ofthe Comparattve Respuatory Soctety

Dr. Stephen J. Peoples, V'84, hasbeenappointed adjunctassistant professorofanatomyattheSchool of Veterinruy Medicine, Purdue Umversity and has been recently promoted to director ofClinical and Scientific Affairs at DePuyOrthopedics. a division ofBoehringerMannheim Corporation. Dr. Peoples iscollaborating with Dr. David Van Sickle, chairman,DepartmentofAnatom)atthePurdueSchool ofVeterinaryMedicine,onvariousresearchprojects evaluating the biocompatibilit}' and ti��;uc: response of biomaterials for use in orthopedic implants.

Dr. Oavid 1. Galligan, V'81, assistant professorof animal healtheconomics, won the 1990 LOTUS awardasoneofthefivebestuserwrittenapplications ofspreadsheettechnologyintheUnitedStatesforhis 1-2-3. DairyProductionMedicineSoftware-Nutri-

tion Module. More than 500 companies, industr}' analysts,consultants,andotherexpertswerepolled fortheirnominationsofthemostsophisticatedand important applications of 1-2-3, and Dr. Galligan's applicationwasvoted bytheeditorsofLOTUSas one of the winners.

Or. WilliamA. Moyer, professorofsportsmedicine, and Rob S�afoo , farrierat New Bolton Center, madepresentationsat theFifth Annual Bluegrass LaminHi!l Symposium, heldin Louis\ille, KY. in January. Rob Sigafoos delivered thefifthannual Charles Heumphreus Memorial Lectureat the UniversityofCaliforniaat Davas in January

De:an Edwin J. Andrews, V'67,wasapanelmember ofthePanelofDeansatthe56thAnnualConference oftheNewEnglandVeterinaryMedicalAssociation. Thepanel discussion topic was "Past, Presentand Future of Vetennary Medicmc: New Dire�tions for the Profession:'

Dr.Gerhard A.Schad,professorofparasitology.is co-editorwithK.S.Warren,RockefeUerFoundation, of Hookworm Disease: Current Statusand New DireNtorts. Dr.Schadhasbeeninvitedtoserveonthe U.S. AdvisoryCommittee to Tbe Kapnek-Simon Mazorod1c Institute for Biomedical Education and ResearchinZimbabwe.ANATOgrantfor"Cloning genesforfunctionalantigensofhookwormAncylostoma" was renewed; rhe project ts acotlaborative oneb)Dr.SchadandDr.Da'idPritch:trd,Univer'iil>or Notungbam, England

John Rawdon,agraduatestudentinparasitology,won fmaprizein theStudentResearch CompetitionsponsoredbytheHelmjnthologicalSocaetyofWashington. Rober1M11n, alsoagraduatestudentinparal>itology, wonlirslprizeinthecompetitionsponsoredbytheNew Jersey Society for Parasitology.

Dr. David Nunamaker. V'68, JacquesJennyProfessor ofOrthopedicSurgery.presentedapaper.co-authored by Or.Dean\\'. Richardsan, assi�tant professorof surgery, and Dr. SimonTurner. Color.tdoState Universityon "-pJateLuung: ATechruquethat ImprovestheFatigueLifeofCompressionPlateFixation." This presentation wasmade at lhe Second Conference of the (memational Society for Fracture Repairandw�heldattheMayoClinicinRochester. MN,andat HennepinMedicalCenter,Minneapolis,MN

ons

Dr. Ilene 0. Amold, \-''89, residentinavianmedicme and pathology. presentedacasereport ..An Outbreak of Psittacine Herpesvirus tn Rosellas" at Lhe Annual Conference of the Association of Av1an VeterinanansinPhoenix,AZ,inSeptember.Atthe 6lndNonheastemConferenceon Avtan Diseasesat the UniversityofGuelph, Guelph, Ontano, Dr. Arnoldpresentedtheresultsofthefirstpartofher studyon "Mycoplasma gal/isepticum: TransmissibilityandPathogenicit}oftheLiveF-strainvaccine inCluekensandTurkeys."Atthesamemeeting, Dr. Jef(re)' Hunchar, V'79, lecturer in avian medicine andpatholog}.presentedtheresultsof"Achallenge study using a field isolate of Avian Pox."

Dr. Robert Eckroade,associateprofessorofpoulrry pathology, wasa keynotespeakerat the Eighth Australian PoultryandFeedConvention.inOctober in Gold Coast. Australia.

Or. Robert M. Kenney, professor ofanimal reproduction, was amongthe first inductees into The Equine Research Hall of Fameat the Universityof Kentucky. Eight researchers from theUnitedStates and four from foreign countri� ""ere recogmzod dunngthe Decemberceremonies at Ke\:neland near Lexington, KY.

Dr. PeterDodson,associateprofessorofanatomy,is the ed1tor, togetherwirh David .B W�tshampel and HaJszkaOsmolska,of TheDtnosourto, anewbook on dinosaurspublishedby tbe Univcrshyof California Press.

Dr. Robert . Hoge, \"55, was named the OutstandingPractitionerfortheFarW�tRegionby the American Animal Hospital AssoctattOn at the organi7ation's meetingin October. The Regional Practitioner Award is presented to an AAHA veterinananforcontributionsthathavebeenmadeto veterinary medicinewhile in privalc practice.

Dr. Ralph E. Werner. V'68, recentlybecameoneof only 30 diplomates ofthe American Board of Veterinary Practitioners tobe recenificd. It is the only spcdalt)' board to require recertification every ten years.

Dr. Linda M. Wood, V'87, and Dr. William J. Bacha.Jr. aretheauthorsofthe Color Atlas of Veterinary Histology. The book, a first ofits kind, waspublishedby Leaand Febiger. Or. Wood isa lecturer in comparative microscopic anatomyat the School,and Dr.Bachaisadjunctprofe�orinanimal biology.

Or. Colin E. HarveJ, professorofsurgery, was irutalled as president ofthe American Veterinary Dental College in November Dr. Harvey recently presented contmuingeducation programs in smaJJ animaldentistryinJapan,Norv.ay.ItalyandFrance, as well asseveral locations in the USA. He also presented reports ofrecent research proJectsatthe British Veterinary DentalAssociation meetingand the Annual Meetingofthe American Veterinary Dental College.

Dr. Wayne Riser, emeritus profesor of pathobiology, washonored bythe World SmaU Animal Association, for his leading role in establishing the organization and forhis efforu in trainmg veterinarians in Europe and Africa in the 1940s and 1950s.

Dr. Donald F. Patterson, Charlotte Newton Sheppard ProfessorofMedicine; Chief, Section of Medical Genetics, received the OklahomaState

Dr. Peter Dodson (right) on location in Montana during his annual summer dig for dinosaurs.

UniversityVeterinaryMedicineAlumniAssociation DistinguishedAlumniAward.

TheSchoolwaswellrepresentedattheAmerican CoUegeofVeterinaryRadiology1990AnnualScientific Meeting.PaperswerepresentedbyDr.Gail K. Smith, V'74,assistantprofessorofonhopedicsurgery, Dr. Jeffrey A.Wortman,Dr. H. MarkSaunders,andDr. CurtisC. ScbeUing, V'85,lecturerinradiology.

The 1990 UniversityResearch FoundationAward recipientsintheSchoolorVeterinaryMedicineare;Dr. MichaelGoldschmidt,professorofpathology;andDr. Kevin hanley,assistantprofessorofdermatology;Dr. DieterM.Schifferli,assistantprofessorofmicrobiology;andDr. PaulaS. Henthorn, assistantprofessorof medicalgenetics.

TheMorrisAnimalFoundationhasfundedthesecond phaseofathree-yearcase/controlstudy.examining colicnsk factors Theprincipalinvestigatorofphase 1 ofthestudywasDr.CharlesR.Curti'i,whoruedthis faUofleukemia.Dr.Curtiswasinlargeparlresponsiblefortheuniqueapproachofcomputeranalysisinuse

New Bolton Center Day at the Races

Dr AllenWeintraub.whap-despitetheweather guestsenjoyedachampagnecarriagedri'etoNew BoltonCenterDayattheRat."t.<>atSaratoga.

TheVeterinarySchoolisfortunatetohavethe generoussupportofmanyfriendswhomadepossible the1990NewBoltonCenterDa)'attheRaces.Fort.h:JS �pec1aloccasion,alltheAugust IOthracesatthe SaratogaRacecourseexceptthefeaturewerenamedto honoroutstandinghorsesincludingBANKER'S LADY.HEIGHTOFFASHION,HOISTTHE FLAG,MISSHUNTLNGTON,ROCKEMBACK, SMARTANGLE.WEEKENDSURPRISEand ZACCIO.

Oneoftheguestsofhonorat rheeventwasthe artist,Mr.PeterWilliams,whohadkindlydonateda paintingfor�onthemvttation.ThoughrainfeUon theIOih,11didn'tseemtodampenmterestinLhislovely oilpaintingwhichalsowasauctionedduringthe luncheontobenefittheCenter.

\trs. J. Ma.'<wellMoranchruredtheAdvisory Committeewhichsuccessfullyraasedmorethan$84,000 tosupponlasersurgeryresearchonrespiratory problemsandtoequipthenewtreadmillareainthe sportsmedicinefacilityatNewBolton.

NIH Grants

TheNationalInstitutesofHealthhaveawarded Dr.DavidM. Nunamaker, V'68,JacquesJenny ProfessorofOnhopedicSurgery,athree-yearresearch granttostudy"FatigueofBone:Relationshipsof Exerct�."Thisgrantforapproximately$777,434will beundenakenO\'erathree-yeartimewithDr NunamakerastheprincipalinvestigatorandDr. MichaelProvost.V'88,asaco-mvesrlgatorinthe project.Theprojectisdirectedatamorecomplete understandingoffatiguefailureasitoccursinboneand attherelationshipsthatdifferentexerciseregimeshave onLhemechantcalandgeometricparametersofbone andthebiologicalreactionofbonetothoseexercise programs.Theresearchersproposetousethehorseasa spontaneousmodeloffatiguefailure(buckedshins)to testthehypothesisthathighsrrainexercisecauses decreasedStiffnessofbone.Thisstudywillalso reconstruct fractureinjuryinboneusingimageanalysis techniquestoaUowforthree-dimensional reconstructionontwo-dimensionalhistologicsections.

Dr.SueM.McDonnell,Directorofthe ReproductiveBehaviorProgram,hasreceivedafiveyear"ResearchCareerDevelopmentAward,''fromthe NationalInstituteofNeurologicDisordersandStroke, Divis1onofFundamentalNeurosciences.Theprojectis entitled''PharmacologicalManipulationofErection andEjaculation. •' Mechanismsofmammalianerection andejaculationwill bestudied principallyinlhe stallion,butalsoinbullsandboars.

TheNationaJ InstituteofAllergyandinfectious Diseasehasawardedafive-yeargrantto Dr.JayP. Farrell,professorofparisitologyandHead.laboratory ofparisitology,tostudytheactivationandregulation ofT-helpersubsetsduringimmuneresponseto cutaneousleishmaniasis.Thisformofleishmaniasisis causedbyaprotozoaparasite,Leishmaniamajor.The diseaseisprevalent in theMiddleEast,Centraland SouthAmerica,andAsia.Affectedpeoplesufferopen cutaneousulceratinglesions.\\hJchmaytakemany months,orevenyears,toresolve.

forthecolicriskfactorstudy. Dr. GarySmith,assistant professorofpopulationbiologyandepidemiology,and Dr. Mathew Reeves,lecturerinepidemiology,have beennamedco-principleinvestigators.Theprincipal investigatorasDr.M.D.SalmanofColoradoState UniversitY.

TheRobertH.WinnFoundationhasawardedagrant toDr.Gall K. Smith forthestudyofhipdysplasiain cats.Dr.SmithalsoareceivedagrantfromTheSeeing Eye, Inc. throughtheMorrisAnimalFoundationto continuehiscaninehipdysplasiastudy.

Dr. Dorudd A. Abt, V'61,RobertA.MarshakTerm ProfessorofAquaticAnimalMedicine,hasbeen appointedadjunctprofessorintheDepanment of EnvironmentalStudiesatTuflsUniversitySchoolof VeterinaryMedicine.Dr.Abtalsowasappointedtothe BoardofDirectorsoftheNortheasternRegional AquacultureCenterastheMarineBiologicalLaboratory'srepresentative.

Dr. W. Jean Dodds-Derman, adjunctprofessorof medicme, receivedtheGainesFidoAwardinFebruary, shewasnamedWomanofthe Yearforherworkas cliret.:toroftheComparativeHematologyLaboratoryin NewYork.

Honors for Dr. Adrian Morrison

TheAmericanAssociationfortheAdvancement ofSciencepresentedtheScientificFreedomand RespollSibilityAwardtoDr.AdrianMorrison, prof�orofanatom�·andHead,laboratoriesof anatomy.ThetributecitesDr. Morrisonfor"his dedicatedpromotionoftheresponsibleuseofanimals inresearchandhiscourageousstandinthefaceofg.reat personalriskagainstattemptstocurtailanimalresearch essentialtopublichealth."

InNovember 1990

Dr.Morrisonreceivedthe DistinguishedServiceAwardoftheSooetyfor NeurosciencesandtheRickSimpsonAward,givenin memoryofthefounderoftheIncurably111 forAnimal Research.Dr.Morrisonisthefirstrecipientofthe MahoneyInstitute'snewlycreatedDirector'sAward, giveninrecognitionofhisdedicationtoneuroscience andhiscourageoussupportofthehumaneandethical useofanimalsinbiomedicalresearch.

Visitorsat Woods Hole - Universit) President Sheldon Hackney and Dean Edwin J. Andrewstour the\'eterinarySchool'sfacilit)'at Woods Holewith Dr. DonatdA. Abtwholc;showingthem amollu'lk, an animlll studied by the Penn contingent at tbe Marine BioloaicaJ Laboratory.

Deafness in Dogs

Inpuppies,theearcanalsarc:�ealeduntil 12to 14daysofage.soallnew-bornsarcdeaf.Aftertwo weeks of age, deaf animals usually are difficult to arouse from sleep. The animal may be over a year before the owner recognizes the problem. Care of deafpels requires a h1ghJy dedicated owner and specialtramingmethods.Adeafanimal mayreOe.xly bile wben startled and may have other behavior problems, but many deaf animals grow normally.

Inheriteddeafnessoftenisassociatedwuhwhite color (piebald gene) and with the merle gene. It is generally uncommon in the caninepopulation. In breedsWithahigh incidence,conclusiveevidenceof deafnes...maybeobtainedbyhavingtheanimal tested at spe<:ial referral centers. Affected animal-; should not be used for breeding.

Thisisoneofthemanyconditionsthatshould beconsideredbybreedclubswhentheyareworking on a program to recognize and eliminate mherited problems.

''Mad-Cow Disease''

Bovme spongiform encephalopatb} (BSE)is a fataldegenerative disease affecting the �ntral nervous systemofcanle. It was first diagnosed in Great Britainin 1986andisnot known10c.xislin the UnitedStates.Therehasbeenno�demificevadence todatethatindicatesBSEisa human healthhazard.

Cattlewiththediseasemayappearquitenormal for years. Then affected animals show changes in temperament such as nervousness and aggression, incoordination, decreased milk production and, eventually,death.Thecauseisnot knownandthere is no treatmem. The diagnosis1S confirmed postmortembymicroscopicexaminationorbraintissue; thereisnotesttodeteu thediseaseinaliveanimal.

TheIITlponation oflivecattleandzooruminants fromtheUnitedKingdomhasbeenprohibatedsince July 1989 bythe United States Department of Agriculture.Also, therehasbeennoimportationof British meat or bone meal Thesale of "high-risk tissues··-chiefly braansand:sweetbreads-forhuman consumption bas been banned in Britain.

�afeguards the right to own und breed "man's best friend."

A Canine Good Citizeo program has been developedbytheAmericanKennelClub. Itspurpose is to demonstrate that the dog, as a companion to man.canbearespectedmemberofthecommunity. andcanbetrainedandconditJonedalwaystobeba"e inthehome, inpublicplace�andin thepresenceof otherdogsinamanner that will renectcreditonr.he dog. The program 'leeks to identify and recognize officially those dogs that possess the attributes that enable them to sene effectively as personal companions and as members in good standing with thecommunity.Thetestsarede�ignedtoshO\\ thata dogwelcomesbeinggroomedandcanbeapproached byastrangerinanaturaleverydaysituation. Thedog must walk on a loose lead.. walk through a crowd withoutstrainingattheleash, "si£"and"down"on commandand''stay"inpositionascommandedb) the handler. The dog should shm\ no more than a casual inter�t in other do� and should not bark. showaggressivenessortrytorunawayifthereisa distraction�ucbassuddennoise,ajoggerorperson onabicycle. Ifleft alone, thedogshouJdnotbark, whineorregJsteran}thmgotherthanmildagitation. The dog must not growl, bite or auempt to attack any person or other dog.

In 1807. Dr. Benjamin Rush proposed veteriua•yt:l.lucation in a lecture at lhe Med•cal School of the University of Pennsylvania, The title was "On theDutyandAdvantagesofStudyingthe Di�eas� of DomesticAnimals, and the Remedies Proper to Remove them."

Thereasonsgivenwere:(l)the·'absurd,painful and destructive" treatment to which they were subjected when diseased, by uninformed or misinformed well-meaning individuals; (2) the gratitudeweowethemfortheservicesandmaterials they furnish; (3) to guard agamst the spread of diseasefromthemtomanthrough thefoodproducts and other materials they supply; (4) to prevent the extensive losses ofantmals and their products by "epidemics of destructive diseac;es''; (5) to ''add greatly to the certainty and usefulness of the professiou ofmedicine as faras it relates to the humanspecies...themaner10 which1berc:moteand proximatecauses of disease produce their morbid effects" being ''thesameasinthe human body,and mostofthemedicine''producing • 'inthemandinus m:arly a similar operation"; and finally, (6) ..the precepts in the Old and New Te.'itaments, which recommend kindness to them and protection from outrage and oppression."

The first class entered the University of Pennsylvania's School of Veterinary Medicine in October 1884.Therewere l2facultymembersand29 students, ten of whom graduated in 1887.

The 105th class graduated in 1990. The total number ofgraduates is 4599, of whom 942 are �omen. At thepreseut lime, thereare 100standing faculty members.

"One Medicine'' is often used in describing courses taught. There is great similarity between veterinaryandhumanmedicine. Eachcontributesto theother.Avastamount ofknowledgethathasbeen developed has resulted in specialization and fewer generalpractitioners.Wehaveimprovedtreatments andmethods. butalookbackintove£erinaryhistory "hows that thereasons for studying veterinary medicine remain the same now as overa hundred years ago.

BSEbelongstoagroupofbraindi�orderswhich includescrapie,adiseaseofsheepin\\ruchaffected arumal� tend to scrape themsdves agamst fences. rocks and walls. There have been probibilions against sheep and goat importation from Great Britain totheUnitedStatesformanyyears. lnthis country, research continues on '\c.rapie and there i!. increased surveillance to detc<:r BSE should it be introdu�d.

Therehasbeenagreatdealofpublicityinthelay press,becausethisissomelhingnew.Thereismuch speculation. particularly since the cause is as yet unknown. The risk Of transmiSSIOn tO human!. is remote.

Canine Good Citizens

Thepet overpopulation problem is leading to greater anti-dog sentiment. In San Mateo County, CA, legislation is proposed to ban all dog and cat breeding.Over10,000unwanteddogsandcatswere euthanized in that county last year. The Humane Society of the United Statesestimates that onequanerofdogsinsheltersarepurebred. Responsible dog breeders are organizing to protect purebred dogs,andareparticipatingin brcedrescueprograms.

Asignificantpartoftheproblemaretho�oedog owners who do not take lhe time and effort to properly train their dogs and cum them over to SPCAs when they remain unruly. According to the American AnimaJ HospilaJ Associarion, more cats and dogs are eutbanized each year as a result of behavior problems than any medical reason. including old age. Obedience traming can help correctminor problems, but it isnotthesolutionto others. especially aggression. Responsible breeders should work to prevent abandonment, abuse or neglect of any animal and make an effort to place puppiesinhomeswheretheywiU receivepropercare and training. Pets should be spayed or neutered.

There are too many dogs beingproduced - by a.ccidentandbybreedingindic;criminatelyforprofit. Some kind of control is needed. There are not enough good homes for all Lhe dogs. We need to work for responsible dogowner legislation that

ThereisabehaviorclinicatVHUP(Veterinary Hospital of the Unhersily of Pennsylvania). For more information. you may te-lttphooethe dinieat 215-898-3347.

Book Review

DogShowing-AnOwner'sGuidebyConnie Vanacore (Howell Book House, 866Third Avenue, New Vorl.., NY 10022, $19.95)

The first recorded dog show took place in Newcastle-on-Tyne,Englandin 1859with60entries forpointersandsettersonly.The firstdog'ihowin theUniled States was held by Westminster Kennel Club, in 1877.withtnorethan35breedsrepresented. This book e.�tplains the present-day world of dog showing.

Atnetican Keouel Club shows and classes offeredaredescribed.Therehad"iceon�electingthe nght breed, including obse�mg at dog show�. and where to purchase a show dog. "Beware of the breederwho guaranteesthatthepuppywillfinishit�o championship. The most that can be guaranteed is that the puppy is healthy, appears to be mentally sound,and foritSage, isstructurallycorrect...There are chapters on health and maintenance or a show dog,groomingandtraining. • 'Grooming ic;alifelong process.whetherornotyouintendroever�howyour dog."

Preparing for theshow ring may start with attending handling classes. Then match shows provide an opportunity to practice. Everything you needto knowaboutpointshowsiscovered-howto enter,whattotake,whattowear,ringprocedureand how judging progresses. Junior Showmanship is discussed as well as are ProfessiOnal Handlers.

Theappendixgivessamplecontractsandsample entry formsaswellasaglossarydefiningcommonlyusedtermsanddiseases.A "Special" isatermused todescribeadogorabitchwhichhascompletedits championshipand is in competition for Best of Breed.

Thebookcoversconformattoojudgingonly.It does not mclude Obedience. lL is an exceUent guide for those interested in breed competition.

First Hill's Pet Products Dean's Scholar Named

Robin Pullen, a senior student, was named the frrst HiU's Pet Products Dean's Scholar at the Universaty of Per:mylvania School of Veterinary Medicine.

The scholarship is funded by a $50,000 endowment generated through the Hill's Pet Products College Feeding Program initiated in 1988. Since its inception, this progTarn has raised more than S75,000 from theproceedsof the sale of Hill's Pet Products to students, facultyand staffat Penn's veterinary school. rt is expected that funds will be in band soon for a second Hill's Pet Products Dean's Scholar.

The Dean's Scholar program at the Veterinary School was initiated in 1989 with the goal of establishing a minimum of 100 Dean's Scholars; currently there are 18 such scholarships.

Hill's Pet Products, in addition to enabling Penn to endow a Dean's Scholar, suppons a resident in nutrition, funds veterinary dental research, and provides part-time funding for a resident in vetermary dentistry. The company also awarded four annual!>cholarships to students, and it is a sponsor of the Penn Annual Conference.

Scholarships

A number of J>tudent::. were named Dean'� Scholars: Michael PensenstadJu, V'94, and El}<,a M. Braunstein, V'93, are Dr. M. Josephine Deubler Dean's Scholars; Arthur Jankowski. V'94, is The Anne Lmn White Dean s Scholar; Jean M. &tkowski, Y'91, is The Mrs. Jack Sallhardt Dean's Scholar; Lance H. Bassage, V'93, is The Ethel H. Mitchell Dean's Scholar: Kirk Smith, V'91, is The Bruce J. Heim Dean's Scholar.

The Pennsylvania Veterinary Foundation awarded tJn: Dr. Palace H. Seitz Memonal Scholarship to John J. McCauley, V'92. The Dr. Samuel B. Guss Memorial Scholarshipwas awarded to Jennifer A. And�, V'91. The foundation

Academic Cooperation between School and Japanese Vet School

On the occasion ofthe ccntenmal celebration of Azabu University in Japan the University of Penmylvania School ofVeterinary Medicineand the School of Veterinary Medicine of Azabu University signed a Memorandum on Academic Cooperation between the two institutions.

Both 5Chools agreed to promotecooperation in thearea of research and education and to exchange academic material5, publications and other information. Both schools will promote exchanges between the two faculties and encourage exchanges between students once a year during �ummer vacation.

A number of Penn's \l!ll!rinary faculty have traveled to Azabu Universaty to lecture at the veterinary school. Twogroups ofstudents from Ihe Japanese School have spent a week each at VHUP to observe the clinics. A third group's visit is planned this summer.

Dr. Darryl Biery and Dr. Charles Newton traveled to Japan to attend lbe centennial celebrations and to participate in the signing ceremony.

awarded the Dr. Samuel F. Scheidy Memorial Scholarships to Mary M. Bowser, V'91, and KirkT. Smith, V'91. ThePVMA Auxiliary Scholarship was awarded to Lori Lynn Ludwig, V'92.

Mary M. Bowser received the Westminster Kennel Foundation Scholarship. Ms. Bowser and the other three recipienls of the scholarships were presented with certificates during the eveningjudging of the Westminster K.C. dog show at Madison Square Garden, New York. The Berks County Kennel Club awarded two scholarships, the recapients are Kimberly Ann Werner, V'91, and John Melniczek, V'92. Gregg Campbell, V'91, received a scholarship from The Lloyd's Underwriters, lloyd's Brokers and KentuckyAgentsJoint Equine Research and Education Committee. Lisa Macom. V'91. received the Janet F. Cottier Scholarship from the Princeton Small Animal Rescue League. Tiffany BogMrt, V'9'2, is the recipient of a scholarship from the Burlington County K.C. The Mispillion K. C. awarded the William E. Spence D.V.M. Scholarship to Corinne A. Dunagan, V'92.

The Plainfield K.C. provided scholarships for Camllle OeCiemeoti, V'94, and Joyce Koch, V'91. Four senior !>tudents, JennllerAndres,James Holt, Debra Lane, and William Rives, are the recipients of a Dr. J. E. Salsbury Scholarship. Herbert Bums, V'92, receaved a Harness Tracks of Amenca-Harry M. Stevens-Peter Haughton Scholarship.

001102 Vilorelli, V'9l, was awarded a scholarship by the Eastern Surfing Association's Marsh Scholarshjp Fund. She also received a scholarship from the National Scholastic Surfing Association. Mark Boccella, V'9t. was awarded the New York Farmers. Inc. Scholarship. Janet G. Jones, V'91, and Jo}ce R. Koch, V'91, were the recipients of the Dorr Scholarships.

Scou 0. Johnson, V'91, received ascholarship from lhe Town of Thomaston Dietz Scholarship Fund. The WiUiam Goldman Foundation awarded five scholarships here at the School The recipients are: Gregol') E. Erdman, V'91, Lori L. Ludwig, V'92, John J. McCauley, V'92, Holl)'8. Mebew, V'93, and Christine M. Rslti. V'93. Pamela Lynn Bendock, V'92, received a scholarship from the Union Coumy K.C. Four Greenberg Memorial Scholarships were awarded to seniors, Mat)' M. Bow.;er, Denu C. Lebo. Ro�rt J. Lewl�. Jr., and Michoel L. Mihllried. LesUe Ziemer, V'91, receiveda scholarship from the Gundaker Foundation.

Hip Dysplasia Diagnostic Clinic

The Veterinary Hospital of the University of Pennsylvania offers special appointments Wednesday evenings for rad10graphic screening of dogs for hip dysplasia. Dogs will be radiographed employing the new diagnostic techniqu� developed by Dr. Gail Smith. This technique measures the laxity of the hip joint and permits the diagnosis of hip dysplasia in dogs as young all four months. An OFA view will also be taken. Litters ofpuppies should be between the ages of 16 to 20 weeks.

The cost ts $150 for an adult dog; $125 for the first pupp}- of a lmer and $65 for each additional puppy in the litter. An appointment is required and can be made by calling 215 898-4680.

Penn Annual Conference

Many thanks to our 750 ve1erinary practitioners, 127 veterinarytechnaciansand 80exhibitors for their enthusiastic support of rhe 1991 Penn Annual Conference. TheDean's Receptionwasattended by 1,100 of our alumni, friends and patrons.

We look forward to seeing youon Wednesday, January 22 and Thursday, January 23, 1992 at the Adam's Mark Hotel.

We acknowledge the support of the following exhibitors who helped subsidize the Conference costs. They are shown here accepting a certificate presented by Dr. Charles Newton.

Dr. William Ray. Hill's Pel Products

Mr. Steven Smolev, Dermatologies for Veterinary Medicine

Mr. Kevin Verde,ur, Peterson Imaging, Inc.

Mr. Todd Bason, A..J. Buck & Son, Inc.

Mr. Barry Furman, Daniel's PharmaceuCieals, Inc. Not �hown, The lams Compan}

Bellwether 30

�ispublishedbytltt!SchoolofVeterinary M«liaMat the UmverstyofPennsylwmia.

Edllor. �

Helmo Weeks Mn GafTI/IllfO

Writcn:

Dr.M. Josephine � AdomGordon

Dt!ubler(AnimalCrackers)

PhyllisHolt4mon

JanKangi/4skl

SusanPer/off

Helma Wft'ks

LynneR.Klunder

Antltony Wood

We'dliketohearyourpraise,criticismsorcomments. Plea�addressyourCOITeSpondent:eto:

HebntlWeds, UniversityofPennsylwuria,Schoolof VeterinaryMedicine,3800SpruceStreet.Philadelphio, PA19/04-60/0(2/j)898-1·#75.

Noneofthesearticlesaretolwl't!prodlu:ed"'lllf)'form withoutthepermissionoftheeditorsofBellwether. 1990 Copyright bytheTrust«Softltt! Unillersityof PenffS.JIIwurio.

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CALENDAR

Alumni Day, New BoltonCenter

Alumni Dinner Dance, Hotel DuPont, Wilmington

Senior Student Dinner Dance, Radnor Hunt Club

Commencement, Annen Theatre, Philadelphia

Continuing Education, Small Animal Radiology, Chest.

VHUP

Continuing Education, Small Animal Radiology, Abdominal Radiology, VHUP

Bellwether

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Philadelphia, PA 19104-6008

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