Constructed on an urban brownfield site that consisted of a surface parking lot set between two garages, the Interdisciplinary Science and Engineering Complex (ISEC) forms the initial phase of a long-term vision to link the University’s Huntington Avenue Campus with Columbus Avenue, span the MBTA and Amtrak rail lines, and connect the Fenway and Roxbury neighborhoods. The motivation for the new ISEC stems from the University’s desire to establish itself as a premier research institution with the most cutting-edge science facility in Boston.