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ZNL100144E 7/19 1. Xu L, Wang Y, Wang S, Wang Y & Jonas JB, ‘High Myopia and Glaucoma Susceptibility: The Beijing Eye Study’ Ophthalmology, Volume 114, Issue 2, February 2007. 2. Holden, B. A., Fricke T. R., Wilson D. A., Jong M., Naidoo K. S., Sankaridurg P., Wong T. Y., Naduvilath T. J. and Resnikoff S. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology 2016; 123: 1036-1042. 3. F. Z., G. Z., & Z. Z. (2018). Investigation of the Effect of Orthokeratology Lenses on Quality of Life and Behaviors of Children. Contact Lens Association of Ophthalmologists, Inc., 44(5). Retrieved May 8, 2019. 4. FDA Approval Letter. 5. Paragon Vision Sciences, CRT Data Report 1/18. Rigid Gas Permeable Paragon CRT® Contact Lenses (paflufocon B) and Paragon CRT® 100 Contact Lenses (paflufocon D) for Corneal Refractive Therapy are indicated for use in the reduction of myopic refractive error in nondiseased eyes. The lenses are indicated for overnight wear in a Corneal Refractive Therapy fitting program for the temporary reduction of myopia up to 6.00 diopters in eyes with astigmatism up to 1.75 diopters. The lenses may be disinfected using only a chemical disinfection system. Note: To maintain the Corneal Refractive Therapy effect of myopia reduction, overnight lens wear must be continued on a prescribed schedule. Failure to do so can affect daily activities (e.g.,night driving), visual fluctuations and changes in intended correction.
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