Best Ozone Therapy Machine An ozone generator, or Ozone Therapy Machine, is a machine that converts oxygen from various causes such as ambient air, dry air, or reduced oxygen into ozone. Ozone generators produce ozone (O3) by combining energy to oxygen molecules (O2), which causes the oxygen atoms to part ways and briefly recombine with other oxygen particles. The ozone is then used for water disinfection and air cleaning. Ozone generators can come in small hand-held areas, all the means up to large-scale modern models that can provide some hundred grams of ozone each hour. Industrial ozone generators work very similarly to ambient air units except they require very clean and very dry air or oxygen and have a corona cell specially designed to generate very high ozone applications.