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The major challenges of research and innovation in health The biology-health sector covers a wide range of disciplines: biology, physiology, medicine, epidemiology, pharmacy, biotherapies, health technologies, public health, human and social sciences. Research in these disciplines accounts for PRUH WKDQ D WKLUG RI DOO )UHQFK VFLHQWLÀF SXEOLFDWLRQV $ QRQ H[KDXVWLYH RYHUYLHZ RI WKHVH GLVFLSOLQHV DQG WKH SOD\HUV DW WKH heart of health research and innovation. Their common thread: improving the quality of life and care provided to patients.
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ancer, chronic diseases, immunology, neurodegenerative diseases, rare diseases, gene therapy and cell therapy, nanotechnologies, the fight against antibiotic resistance, “One Health”: these are all major public health issues that the arrival of SARS-CoV-2 in 2019 should not obscure.
search sites) which bring together medical services, multidisciplinary research teams, resources and efficient shared services. Improving the management of chronic diseases In France, 20 million patients suffer from chronic diseases, which cause many
serious complications, disabilities and physical and moral suffering. Supported by the AP-HP, the ComPaRe research patient community relies on a large e-cohort of 100,000 adult patients with one or more chronic diseases to study the general management of chronic diseases and multimorbidity, to answer specific
Unveiled on 4 February by the President of the Republic, the ten-year cancer strategy 2021-2030 has been allocated nearly €1.74 billion in funding for the next five years, of which €634 million is dedicated to research - a 20% increase compared to the 2014-2019 Cancer Plan. In parallel with the “High Risk-High Gain” call for projects for research into cancers with a poor prognosis and paediatric cancers, the first applications of the data platform will be launched in the coming months to use artificial intelligence to develop treatments. These actions complement the 11 Integrated Research Action Programmes (PAIRs) launched in 2009 by the INCA in partnership with the Cancer League and the ARC Foundation for Cancer Research, and the 8 SIRICs (Integrated cancer re-
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© Ministère de l’Enseignement supérieur, de la Recherche et de l’Innovation
In France, cancer is the leading cause of death in men and the second leading cause of death in women. In 2018 the French National Cancer Institute (INCA) recorded 382,000 new cases and 157,400 deaths. And while the standardised mortality rate fell by 2% per year in men and 0.7% in women between 2010 and 2018, 40% of cancers can be avoided if the four main risk factors are tackled: tobacco, alcohol, unbalanced diet and excess weight. Upstream of prevention, screening and treatment (with new specific immunotherapy drugs including immune checkpoint inhibitors and CAR-T cells, cell and gene therapy drugs), research plays a major role in improving patient care.
Septembre 2021
