NYSCF Innovator Program Impact Report

Fall 2017

NYSCF INNOVATOR

PROGRAM

IMPACT REPORT The New York Stem Cell Foundation

The New York Stem Cell Foundation is accelerating cures for the major diseases of our time through stem cell research.

NYSCF I N V E S T I G ATO R PROGRAMS The NYSCF Investigator Programs support and encourage promising early career scientists whose cutting-edge research holds the potential to accelerate treatments and cures. These scientists are the engineers of tomorrow’s breakthroughs. The Programs provide support for: •

NYSCF – Robertson Stem Cell Investigator Awards

•

NYSCF – Robertson Neuroscience Investigator Awards

•

NYSCF – Ralph Lauren Stem Cell Investigator Award

•

NYSCF – Robertson Stem Cell Prize

•

NYSCF Research Institute Investigators

N YS CF IN VE ST IGATOR PROG R AM S I NSTITUT I ONS O F CURREN T STEM C E L L I NV E STI G ATO RS Academic Medical Center, The Netherlands Broad Institute of MIT and Harvard California Institute of Technology Cincinnati Children's Hospital Medical Center Harvard Medical School Icahn School of Medicine at Mount Sinai Lund University, Sweden Massachusetts General Hospital Massachusetts Institute of Technology Stanford University University of Pennsylvania University of Southern California Weizmann Institute of Science, Israel

IN STITU T IONS O F CURREN T NEUROS CI E NCE I N VESTI G ATO RS Boston Children's Hospital Brain & Spine Institute (ICM), France Cornell University Harvard Medical School Massachusetts Institute of Technology Princeton University Stanford University The Rockefeller University University of California, Berkeley University of California, San Francisco University of Geneva, Switzerland

Creating a global community of scientists leading their generation in cutting-edge research

I N STI TUT I O N S O F N YS C F – RO B E RTS O N S TE M C E L L P RI ZE RE C I P I E N TS Broad Institute of MIT and Harvard Case Western Reserve University Dana-Farber Cancer Institute Harvard University Kyoto University, Japan Stanford University University College London, United Kingdom

I N S TI TU TI O N S O F AL U M N I I N VE S TI GATO RS Broad Institute of MIT and Harvard Case Western Reserve University School of Medicine Columbia University Harvard Medical School Harvard University Johns Hopkins University School of Medicine Massachusetts Institute of Technology Max Planck Institute for Molecular Genetics, Germany New York University School of Medicine The NYSCF Research Institute Stanford University The Rockefeller University University of Arizona University of California, San Diego University of Utah Washington University School of Medicine Weill Cornell Medical College

S

S

N YS CF IN VE ST IGATOR PROG R AM S S I N C E T H E P RO GR A M S ’ I N C E PT I O N

61

SCIENTISTS SUPPORTED

at

38

DIFFERENT INSTITUTIONS THROUGHOUT THE WORLD

NYSCF – ROBERTSON STEM CELL INVESTIGATORS NYSCF – ROBERTSON NEUROSCIENCE INVESTIGATORS NYSCF – ROBERTSON STEM CELL PRIZE RECIPIENTS ALUMNI

NYSCF RESEARCH INSTITUTE INVESTIGATORS

Over

850

YOUNG SCIENTISTS ARE BEING TRAINED IN THE LABS

OUR INVESTIGATORS HAVE WON

over

400

of these

61

INVESTIGATORS

AWARDS AND HONORS IN THEIR CAREERS

including:

Presidential Early Career Awards for Scientists and Engineers, NIH Director’s New Innovator Award, Breakthrough Prize, Alfred P. Sloan Foundation Research Fellowship, Pew Scholars Awards, Time Magazine’s “People Who Mattered”

THEY HAVE GIVEN

over

2000

TALKS ON THEIR EXCITING AND INNOVATIVE including at: WORK WORLDWIDE

TED, The Kavli Foundation, National Institutes of Health, Society for Neuroscience

I M PAC T

2100

OUR INVESTIGATORS HAVE PUBLISHED OVER Â PUBLICATIONS THROUGHOUT THEIR CAREERS INCLUDING:

90

PAPERS

102

58

PAPERS

77

PAPERS

PAPERS

158

69

PAPERS

PAPERS

RE S EA RCH AR EAS BY T H E N U M B E R S AREAS OF STUDY 3%

Aging Autoimmune Diseases

3%

3%

10% 3% 8%

8%

Blindness Cancer Cardiovascular Diseases Diabetes

13%

Lung Diseases

13%

STEM CELL RESEARCH AREAS

Gene Editing/Human Genome Neurodegenerative Diseases Stem Cell Biology

3%

Tissue Engineering Alzheimer’s

General

Schizophrenia Rare Diseases

14%

Multiple Sclerosis (MS)

Parkinson's Disease

36%

14%

Amyotrophic Lateral Sclerosis (ALS)

23%

NEUROSCIENCE RESEARCH AREAS

AREAS OF STUDY Neurobiology

9%

Neurotechnologies Development Learning & Memory Decision Making

41%

NYSCF F E L L OW S H I P PROGRAM Through the NYSCF – Druckenmiller Fellowship Awards, NYSCF supports the most talented young scientists at critical junctures in their careers. The program creates opportunities for young scientists to be trained and supported in the pursuit of innovative and groundbreaking stem cell research.

Through their research, this global community of scientists is pushing forward new treatments and cures for patients around the world.

NYSCF – DRUCKENMILLER FELLOWS

N YS CF – DRUCKENMILLER FE L L OWS

Creating a global community of scientists leading their generation in stem cell

INSTIT U T ION S OF ALU M N I F EL L OWS Albert Einstein College of Medicine Columbia University Harvard University Icahn School of Medicine at Mount Sinai Johns Hopkins University Memorial Sloan Kettering Cancer Center New York Neural Stem Cell Institute New York University School of Medicine The Hebrew University of Jerusalem, Israel The NYSCF Research Institute The Rockefeller University The Salk Institute University of Rochester Medical Center Weill Cornell Medical College Weill Cornell Medical College, Qatar Yale University

INSTIT U T ION S OF CU R R EN T F EL LOWS Albert Einstein College of Medicine Icahn School of Medicine at Mount Sinai Memorial Sloan Kettering Cancer Center New York University School of Medicine The Rockefeller University Weill Cornell Medical College Yale University

research

Creating a global community of scientists leading their generation in stem cell research

C U RRE N T I N STI T U TI O N S OF ALUMNI A*STAR, IMCB, Singapore Albert Einstein College of Medicine Angelini, Italy Bar-Ilan University, Israel Columbia University Dana Farber Cancer Institute Harvard University Icahn School of Medicine at Mount Sinai Institute of Biomedicine of Valencia, Spain Johns Hopkins University King Mongkut's University of Technology Thonburi, Thailand Ludwig Botzmann Institute, Austria Ludwig-Maximilians-University Munich, Germany Memorial Sloan Kettering Cancer Center National Institute of Biological Sciences, China New York Neural Stem Cell Institute Northwestern University Oregon Health & Science University Sidra Medical and Research Center, Qatar Soonchunhyang University, South Korea Tel Aviv University, Israel The Feinstein Institute for Biomedical Research The NYSCF Research Institute The Rockefeller University The San Raffaele Telethon Institute for Gene Therapy, Italy TiGenix, Spain University Medical Center Hamburg-Eppendorf, Germany University of Calgary, Canada University of Padova, Italy University of Palermo, Italy University of Pennsylvania University of Southern California University of Texas Health Science Center VUmc Cancer Center Amsterdam, The Netherlands Weill Cornell Medical College

NYSCF – DRUCKENMILLER FELLOWSHIP AWARDS

59

FELLOWS SUPPORTED SINCE THE PROGRAM’S INCEPTION

at

16

INSTITUTIONS

in

3

COUNTRIES

60

50

NEWLY AWARDED FELLOWS

NUMBER OF FELLOWS

40

30

20

10

2006

2007

2008

2009

2010

2011

2012

2013

2014

2015

2016

2017

YEAR

47

ALUMNI FELLOWS at CURRENTLY BASED

35

INSTITUTIONS

in

13

COUNTRIES

INCLUDING:

United States, China, Italy, Canada, Spain, Israel, Germany, Austria, Qatar, South Korea, Thailand, Singapore, The Netherlands

27

ALUMNI FELLOWS HOLD INDEPENDENT POSITIONS

58%

OF ALUMNI HOLD INDEPENDENT PROFESSORSHIPS

38%

OF ALUMNI ARE BASED AT INTERNATIONAL INSTITUTIONS

I M PAC T

OUR FELLOWS HAVE PUBLISHED OVER

900

PAPERS

IN TOP SCIENTIFIC JOURNALS INCLUDING:

22

PAPERS

16

PAPERS

44

16

PAPERS

PAPERS

44

PAPERS

16

PAPERS

RE S EA RCH AR EAS BY T H E N U M B E R S

3%

3% 25%

19%

STEM CELL RESEARCH AREAS

5%

9% 5% 31%

AREAS OF STUDY Autoimmune Diseases

Cancer & Blood Diseases

Cardiovascular Diseases

Diabetes

Liver Diseases

Neurodegenerative Diseases

Stem Cell Biology

Tissue Engineering

N YS C F I N N OVATO R S • Maria Barna • Kristen Brennand • Valentina Greco Mitchell Guttman • Jacob Hanna • Justin Ichida • Malin Parmar • Sergiu Pasca Jennifer E. Phillips-Cremins • Jay Rajagopal • Kristy Red-Horse • Takanori Takebe • Louis Vermeulen Brian Wainger • Feng Zhang • NYSCF – Rober tson Neuroscience Investigators • Hillel Adesnik Stephen Brohawn • Edward Chang • Winrich Frewiald • Lisa Giocomo • Daniel Huber Zahcary Knight • Maria Lehtinen • Dragana Rogulja • Gregory Scherrer • Kay M. Tye Melissa Warden • Ilana Witten • Claire Wyart • Michael Yartsev • NYSCF – Rober tson Investigator Alumni Paola Arlotta • Deepta Bhattacharya • Ed Boyden • Shuibing Chen • Dieter Egli Christopher Gregg • Christopher Harvey • Takaki Komiyama • Gabsang Lee • Michael A. Long Gaby Maimon • Ravi Majeti • Alexander Meissner • Derrick Rossi • Vanessa Ruta • Paul J. Tesar Marius Wernig • NYSCF Research Institute Investigators • Valentina Fossati • Bjarki Johannesson Daniel Paull • Scott Noggle • NYSCF – Ralph Lauren Investigator • Giuseppe Maria de Peppo NYSCF – Helmsley Stem Cell Investigator Alumni • Valentina Fossati • Darja Marolt NYSCF – Dr uckenmiller Fellows • Laura Andres-Martin • Dafne Campigli Di Giammartino Tae Wan Kim • Hongda Li • Benjamin Lin • Raphael Lis • Ying Liu • Maria Maryanovich Sangbum Park • Brett Shook • Julia TCW • NYSCF – Dr uckenmiller Fellowship Alumni Sriram Bandi • Zhongwei Cao • Ting Chen • Elisa Cimetta • Dilek Colak • Francesco Paolo Di Giorgio Raffaella Di Micco • Bi-Sen Ding • Panos Douvaras • Dieter Egli • Samantha England • Elena Ezhkova Christopher Fasano • Nuria Flames • Valentina Fossati • Alexandre Gaspar Maia • Tamar Hermesh Ya-Chieh Hsu • Sarah Xuelian Huang • Justin Ichida • Keiichi Inoue • Daylon James Bjarki Johannesson • Natalie Kim • Evangelos Kiskinis • Fabien Lafaille • Dung-Fang Lee Gabsang Lee • Larry Luchsinger • Darja Marolt • Ian Martin • Maitane Ortiz-Virumbrales Dominik Paquet • Sandra Pinho • Christophe Raynaud • Pantelis Rompolas • Marco Seandel Jae-won Shim • Shivatra Noi Talchai • Wee-Wei Tee • Maya Tevlin • Maria Themeli Sjoukje van der Stegen • George Kai Wang • Yingying Zhang • Giovanni Zito • Oren Ziv NYSCF – Rober tson Stem Cell Pr ize Recipients • Peter J. Coffey • Franziska Michor Kazutoshi Takahashi • Paul J. Tesar • Amy J. Wagers • Marius Wernig • Feng Zhang NYSCF Research Institute • Kennedy Agwamba • Lauren Bauer Vensand • Katie Brenner Geoff Buckley-Herd • Sean DesMarteau • Panos Douvaras • Patrick Fenton • Eliana Forero Yosif Ganat • Jordan Goldberg • Jenna Hall • Ya-Chu Juliana Hsu • Christopher Hunter Tanya Jain • Travis Kroeker • Ilya Kruglikov • Gregory Lallos • Hector Martinez • Barry McCarthy Paul McCoy • Frederick Monsma • Dorota Moroziewicz • Melissa Nirenberg • Reid Otto Brandon Pearl • Katie Reggio • Tomasz Rusielewicz • Ana Sevilla • Martina Sladkova Bruce Sun • Edmund Tam • Cecile Terrenoire • Rebecca Tibbetts • Matthew Zimmer NYSCF – Rober tson Stem Cell Investigators

The New York Stem Cell Foundation

W W W. N Y S C F. O R G