Invitation to Tender: non-financial support for the Longitude Prize on Dementia

1. Whatarewecommissioning?

Wearecommissioningorganisationsoraconsortiumofindividualcontractorsto delivernon-financialsupportNFSservicesfortheLongitudePrizeonDementia FinalistAwardteams.

Thesuccessfulbidder(s)shoulddemonstratepassionforinnovation,experiencein accelerator/incubatoractivitiesandofferacreativeapproachtodeliversocialimpact throughharnessingthepowerofentrepreneurship Theywillbeabletoconductneeds assessmentofinnovatorteams,providebespokesupportandhaveaccesstoabroad rangeofexperts.Experiencewithaninternationalcohortisalsoimportant.

ThisinvitationtotenderITTisforworkovera15-monthperiodfromSeptember2024 toNovember2025.

2. BackgroundtotheLongitudePrizeonDementia

TheLongitudePrizeonDementiaisa£4.42millionchallengeprizetodrivethe creationofpersonalised,technology-basedtoolsthatareco-createdwithpeople livingwithearlystagesofdementia,helpingthemliveindependentandmorefulfilled livesforlonger £342millionwillbeawardedtothemostpromisingsolutions:

● 24DiscoveryAwardteams£80,000each).

● 5finalists£300,000each)– focusofthistender.

● and£1millionawardedtotheoverallwinningsolutioninFebruary2026.

ThePrizeisfundedbyInnovateUKIUKandtheAlzheimer’sSocietyAS,and deliveredbyChallengeWorks.ThePrizelaunchedon26September2022.Itis governedbyaProgrammeBoard(includingIUKandASDirectors),aninternational expertjudgingpanel10members)andtheLivedExperienceAdvisoryPanelLEAP

Figure1.KeydatesfortheLongitudePrizeonDementia

Thecohort

Whathasalreadyhappened:

InJune2023,ChallengeWorksannounced24teamstoprogresstotheDiscovery Awards receiving£80,000eachandenteringa12-monthdevelopmentsupport stage.YoucanviewtheDiscoveryAwardteamsonourwebsiteandinAppendix2. Appendix3detailstheNFSprogrammedeliveredduringtheDiscoveryPhasebetween June2023andMay2024.

Theinternationaldiscoveryawardcohortarefromthefollowingcountries:UKandIsle ofMan15,USA3,Canada2,Australia1,Colombia1,Portugal1andUAE1

AttheendoftheDiscoveryPhase,the24DiscoveryAwardteamsareinvitedtosubmit tobecomeoneofthefivefinalists Teamswillbeexpectedtohavedevelopedtheir solutiontoaprototypelevel,withatechnologywhosecorefeaturesareusable independentlybythetargetpopulation.Solutionswillneedtohavebeentestedwitha spectrumofrealusersatdifferentstagesofprogression(atearly-midstagesof dementia),todemonstrateinitialevidenceofadaptability

Whatwillhappennext–focusofthistender:

InAugust2024,followingthejudgingprocess,fivefinalistswillbeselectedtoenter thenextstageoftheprizeprogramme Thefivefinalistteamswillbeannouncedin September2024.

ChallengeWorksiscurrentlydevelopingtheNFSthatwillbeprovidedintheFinalist Phase,runningfromSeptember2024toNovember2025.

InNovember2025,thefivefinalistswillbeinvitedtosubmitafinalapplicationtobe selectedtobetheoverallwinnerandbeawarded£1million Theprizejudgingcriteria canbefoundinFigure2

Figure2 LongitudePrizeonDementiajudgingcriteria TablepublishedintheInnovator Handbook(page10inSeptember2022.

3. Scopeofwork

Wearecommissioningasupplier (eitheranorganisationoraconsortium)todeliver NFSservicestofivefinalistinnovatorteamsbetweenSeptember2024andNovember 2025.

AttheendoftheFinalistPhase,thefivefinalistswillbeexpectedtohaveaworking modelwhosefullfeaturescanbeintuitivelyactivatedandusedbythetarget population Thetechnologyshouldhavebeentestedonawidepopulationsample, includingstresstestingwithextremeuserbehaviour,andshouldhaveademonstrated abilitytoadapttoachangeincircumstances Theywillalsobeexpectedtohavea businessplanwithaclearlydemonstratedroutetomarket.

Withthisinmind,theNFSservicesshouldprovidecapacitybuildingsupporttohelp consolidateplansfordevelopingtechnicalsolutions(furtherdetailsintheCoreNFS andsolutiondevelopmentsection).

ThisITTcoversworkrunningfromSeptember2024toNovember2025.

Objectives:

● Toprovideabespoke/tailored/personalised/1-on-1supportpackagetofive internationalinnovatorteamstoprogressintheFinalistPhaseoftheprize programme.

● Todeliversupportinamannerthatisequitabletoallfivefinalistinnovator teams.

● Tosupportthedevelopmentandrefinementofsolutionsinlinewiththe challengestatementandjudgingcriteria(butthesuppliershouldnotbe developingthetechnologythemselves).

● Toleverageyourexistingexpertnetworksinordertosupportthedevelopment ofsolutions

● Tosupporthigh-qualityfinalsubmissionsmeetingthejudgingcriteriaatthelast judgingstageoftheprizeinNovember2025todecideontheoverallwinner.

● Toworkincollaborationwithexistingpartnersandstakeholders,including ChallengeWorks,Alzheimer’sSocietyandtheLondonSchoolofEconomics,to deliverthesupportprogramme

NFSdetailedscope:

BelowisanindicativeplanfortheNFS.Pleasenotethatthisoutlineissubjectto changeandadaptation.Basedonyourownexperienceandexpertise,pleaseadapt theplanaccordinglyinyourwrittenpitch.Furtheradjustmentsmayalsobemadeto tailorthesupportofferedoncethefivefinalistshavebeenselectedinAugust2024 andtheirspecificneedsareunderstood.

Forexample,someinnovatorteamsmaybemoreproblem-ledintheirfocusandwill haveexperienceinthefieldofdementiabutmaylacktechnicalexpertise,whileother teamsmaybetechnology-drivenandwillrequiresupportwithdementia-related expertise Thesupportpackageshouldprovidetailoredsupportaccordingto innovators’needs

CoreNFSandsolutiondevelopment

Thesupplier’skeyroleistodeliverthecoreNFSandsolutiondevelopmentduringthe FinalistPhaseoftheLongitudePrizeonDementia.

Outputsmayinclude:

● Accesstoend-users.Thisisakey,andcommon,barrierthefinalistswill continuetofacewhenco-creatinganddevelopingtheirsolutionswithpeople livingwithdementia.Innovatorsaretobeconnectedwithspecifiedendusers (peoplelivingwithdementiaandcarers)tofurthertestanditeratetheir prototype.

● Providingaccesstomentorsandexpertsfortechnicalanddesignsupport. ExpertiseshouldbeavailableacrossallareasrelevanttotheChallenge, includingdementiacare,co-creation,healthcareandassistivetechnology Supportmaybeprovidedinavarietyofformats,bothone-to-oneand one-to-many.

● Businessdevelopmentandcommercialisationsupport.Innovatorsshouldbe supportedtounderstandboththedementiacaresectorandviableroutesto marketbyspecialistsinbusinessmodellingandcommercialisation The commercialisationsupportshouldhelpinnovatorstobuildacompelling businesscase.Supportmaybeprovidedinavarietyofformats.

● Investmentreadinesssupportandengagementforlong-termsustainability. Finaliststoworkwithimpactinvestmentspecialiststoanalyseinvestmentplans andfeedbackonpitches.Supportopportunitiesfornetworkingwithpotential investorsthroughdedicatedactivitiese.g.roundtableevents. Toensurethelong-termfinancialfeasibilityofthesolutions,ChallengeWorks willrecruitinvestorstoanInvestorAdvisoryPanelandcreatecontact opportunitiesforthefinalistssothattheycanbuilddirectrelationshipswith investorstobetterunderstandwhatInvestorsarelookingforandwhatto considerwhendevelopingtheirbusinessmodel.

● Regulatoryandprocurementsupport.Theregulatoryandpublicsector procurementspaceisparticularlycomplexinthisfield,especiallyconsidering solutionsmayoperateoutsidetheUK Suppliertoensurefinalistscanaccess expertstocoverregulationandprocurementsupportinorderforthemto developviablesustainablebusinessmodelsandensuretheinnovatorsare takingthecorrectregulationandprocurementroute.

● Technologyanddatasupport.Specialistandpersonalisedtechnicalsupportto finaliststofurtherdeveloptheirtechnology.PleaseseeinAppendix3the supportprovidedandthemescoveredintheDiscoveryPhase.

Tonote:

● TheLondonSchoolofEconomics,supportedbyChallengeWorksand Alzheimer’sSocietywillconductanindependentacademicstudytoexamine theeffectsofthefinalisttechnologiesonthelivesofpeoplelivingwith dementiafromSeptember2024intheFinalistPhase.Thisstudywillalso provideourfivefinalistswithfeedbacktomodifyandimprovetheirdesigns. ThedatawillfeedintothewinnersubmissioninNovember2025.

● ChallengeWorkshaspartneredwithAmazonWebServicestoprovide11 AmazonWebServiceAWSconsultantsupportandcloudcreditsforthe finalistsdevelopingtheirsolutionswithAWScloud.

● ChallengeWorkshascontractedwithSevenCommunicationstoprovide communicationsandmarketingsupportforthefinaliststobuildabrandand communicationsstrategytoraisetheprofileoffinalistsandgivethemthebest chanceofscaleandsustainability

● Theremaybeotherpartnerssupportingteams

● DuringtheFinalistPhase,theinnovatorteamswillalsoreceivefinancial support£300,000each),administeredbyChallengeWorks.

SpecificNFSactivitiesforsuppliertoconsider

● Needsanalysis:

○ Reviewinnovatordocumentationandconductaneedanalysisinterview withthefivefinaliststounderstandtheirneedsinthenextdevelopment phaseandbuildontheChallengeWorks’analysisofteams

○ DesignpackageofsupportwithChallengeWorksbasedonthese insights.

● Attendanceanddeliveryofsessionsatin-personeventswithfinalistseg finalistwelcomeworkshop.

● Formatofsupportandresources:

○ Mentoring-innovatorsshouldbeprovidedwithadedicatedmentorwho isamainpointofcontactthattheycandiscussquestionswith.

○ Tailored11sessions-toprovideaccesstoanexpertnetworkand leveragenetworkandassociatestocreateresponsivesessionsthat meettheneedsoftheinnovator.

○ Groupmasterclassesandworkshops-masterclassesandworkshops withexperts.

○ Creatingandfacilitatingnetworkingandcollaborationopportunitiesfor innovators,forexamplethroughdirectintroductionsorfacilitated networkingeventswithpotentialpartners,industryexperts,and mentors.

○ Useofphysicalspaceandvenueforevents.

○ Thespecificresourcesofferedwillbebasedontheneedsassessment ofthefinalists

4. WorkingwithChallengeWorks

Thesuccessfulprovider(s)will:

● leadthedevelopmentoftheNFSstrategyanddelivery,withoversightfrom ChallengeWorks

● deliversupport/resourcesusingavarietyofdifferentformats,includingbutnot limitedto:virtualworkshops,11sessionsandexpertwebinars

● leveragetheirexistingnetworks

● allowforadegreeofflexibilitytoprovideresponsivesupporttopotentialneeds identifiedasthesupplierengagesfurtherwiththefinalists.Furtherneedsmight ariseastheteamsprogresswithusertestingandthroughthesupport

● adheretoallofChallengeWorks’reportingrequirements

● attendregularmeetingswiththeChallengeWorksteamtoensuretheyhave necessaryvisibilityoverNFSactivities

Tosupportthechosensupplier,ChallengeWorkswill:

● workcloselywiththesuppliertoreviewandsign-offontheNFSworkpackage, ensuringthismeetstheneedsofourclientandinnovators

● ensurerelevanton-boardingofthesuccessfulsupplierwilltakeplaceassoon aspossiblepost-contractinginordertofacilitateefficientcommencementof work

● haveregularmeetingstomonitortheprogressoftheNFS

● sign-offallNFSdeliverables

● provideadedicated‘informationhub’webpagefortheinnovatorsincluding documentsharingandaccesstoexperts

5. Requiredexpertise

Thesuccessfulprovidershouldhave:

● relevantdomainexpertise

○ Atrackrecordofdeliveringpackagesofsupporttoearlystagetech ventures.

● communicationandmanagementskills

○ Experiencemanaginginternationalprogrammeswithmultiplework streams.

● desirableknowledgeandexperience,whichincludes:

○ ademonstrablegraspofwhatishappeningaroundtechnological innovationinassistivetechanddementia

○ associatedsocietalandmarketopportunitiesandchallenges

6. Indicativebudget

● Thebudgetfortheengagementisupto£336,000GBP(inc.VAT Please note,thisisthistotalbudgetfortheentireNFSpackageintheFinalistPhase for15monthsandcouldbeallocatedacrosstheselectedorganisation/s. Partnershipsarewelcome.

● Theproposedbudgetshouldbeitemisedanddetailthecostsfordesign, developmentandimplementationoftheservicesandshoulddemonstratevalue formoney

● Paymentswillbereleasedinstagesalongsideagreedmilestones,providing thesehavebeenmet.

● Thefinalmilestonesshallbeclearlydocumentedinanycontractenteredintoas aresultofthisscope,andinaccordancewithitstermsandconditions.

7. Indicativeprocurementtimetable

DATE ACTIVITY

Monday 13May2024

Wednesday29 May2024

Friday7June 2024

Wednesday26 June2024

TenderissuedonNestawebsite

Biddersconfirmviaemailtheyplantorespondtothetenderand submitanyadditionalquestionstoclarifythebrief

Bidderstosubmitwrittenresponsestothetender

Shortlistedbiddersinvitedtointerviewonthebasisoftheirwritten responses

8 10July2024 Interviewsconducted,whichwillbereviewedandevaluated againsttheselectioncriteriaSection10

18July2024 Programmeboardapproval

19July2024 Informsuccessfulbidder

22July-2August 2024

w/c12August 20234

Contractingperiodwithsuccessfulbidder

InitialplanningwithChallengeWorksteamandneedsanalysiswith innovatorteamscommences

8. Howtorespond

TheITTisinthreephases:

1.Organisationsorindividualsheadingupaconsortiumarerequestedtoconfirmthat theywillrespondtothecallforproposalbyemailingLongitudePrizeonDementia (longitudeprizedementia@challengeworksorg)inaccordancewithalltheinstructions andtermsandconditionssetoutwithintheencloseddocumentationbyWednesday 29May2024at1159pmBSTLondon,UK.

2.Writtenresponses,outliningyourapproachshouldbesenttotheabovecontactby Friday7June2024at1159pmBSTLondon,UK.Pleasekeepproposalsundereight A4pages Budget,biographiesofteammembersandlinkstootherinformationwillnot becountedwithintheeightpagemaximum.

WerequestapplicationstobeinEnglish.

a. Credentialsandcasestudies(relevantexperienceofprovidingsimilarservices andtargetingsimilaraudiences,providinguptothreespecificexamples)

b Initialresponsetothebrief,outliningyourcreativeapproachtodelivery

c. Costingbreakdownasoutlinedinthebudgetsection.

3.Basedonwrittensubmissions,aselectionofbidderswillbeinvitedtointerview.

9.Selectioncriteria

Proposalswillbeevaluatedagainsttheselectioncriterialistedbelow.

SelectionandAwardcriteria

1. Capabilityoforganisationandqualificationsofproposed individuals(staffandsubcontractpersonnel)

Pleaseexplainwhetheralltheresourcesarein-houseoroutsourced Ifoutsourced, pleaseoutlinehowyouproposetodelivertheservicesandwhowillbeleadingthis.

Pleaseprovidethenamesandcontactinformationforthreeofyourclientswhocouldbe contactedforreferencesofyourorganisation’s/group’scapabilities,processand relationship

2. Credibility,creativityandproposalapproach

Planofproposedactivities.

Pleasedescribehowyouwouldapproachthisprojectandhowyouwouldworkwith ChallengeWorkstoensuresuccessindeliveringnon-financialsupportfortechnology anddata.

Creativeexamplesofthetacticsyouwouldproposetoensurethatsuccessisachieved.

Whatdoyouseeasthepossiblechallengestodeliveringtheworkandhowcanyou mitigatethem?Howdoyouproposetomeasureandevaluatemeaningfulreachandthe successoftheactivities?

3. Valueformoney

Pleaseprovideanitemisedbreakdownofyourproposedfeesandpricingstructure, includingabreakdownofhowthebudgetwouldbesplitacrossfeesandimplementation Wheredoyouexpecttoseeresourcesalignedwithactivity?

Pleasealsoindicatewhichteammemberwillleadonspecificaspectsoftheworkand breakdowntherateperindividual/level.

4. Contractmanagementarrangements(processforensuring on-timedeliverywithexceptionalhighquality,while demonstratingcostefficienciesandflexibilityofproposalsto adapttochangingneeds):

Pleaseoutlineyourapproachtoprojectmanagement,planningandexecutionofthisrole andyourreportingplans/arrangementsdescribinghowyouwillworkwithNestaasa contractor.

Appendix1TermsandConditions

Thisappendixprovidesthetermsandconditionswhichwillgovernyoursubmissionof aproposaltoNesta.Youarerequiredtoreadthisappendixcarefullytogetherwiththe ITTbrief(includingallitsannexes)beforesubmittingaproposal Bysubmittinga proposal,youacceptthesetermsandconditionsandyouagreetoabidebythem If youdonotagreetothesetermsandconditionspleasedonotsubmitaproposal.

1. Submittingaproposal

11 Bysubmittingaproposalyouconfirmthat:

1.1.1 YouhavenoactualorpotentialconflictofinterestwithNesta(including Nesta’sTrustees,officersoremployees).IfatanytimeduringtheITT processyoudiscoveranactualorpotentialconflictofinterest,please informNestapromptly;

1.1.2 YouhavelegalcapacitytosubmitaproposalinresponsetothisITTand areactinglawfully,ethicallyandingoodfaithinyourdealingswith Nesta;

1.1.3 Youhavesufficienttime,skill,experienceandresourcestocarryoutthe servicestothehighestprofessionalstandardsexpectedofacompetent supplierofservicesidenticalorsimilarandareabletoobtainall necessaryrights,licences,consents,waivers,approvals,permissions, permits,certificatesandinsurancesnecessarytoprovidetheservicesto Nesta;

1.1.4 Yourtenderwillremainopenforacceptanceforaperiodof90days.A tendervalidforashorterperiodmayberejected;

1.1.5 Allinformationcontainedinyourproposalistrue,accurateandnot misleading;and

116 NestamayshareyourproposalwithanythirdpartyasNestainits absolutediscretiondeemsnecessaryforthepurposeofevaluation

2.Compliance

21 Nestareservestherighttorejectordisqualifyyourtenderwhere:

2.1.1 YoufailtocomplywiththerequirementsofthisITT(includingbutnot limitedtothesetermsandconditions),yourtenderisincomplete,oryou areguiltyofaseriousmisrepresentationinsupplyinginformationin responsetothisITT;

2.1.2 YourtenderisreceivedafterthedeadlinesetoutinthisITT.Nestawill notconsideranyrequestsforanextensionofthetimeordatefixedfor thesubmissionofresponses;

2.1.3 Thereisachangeinyouridentity,control,financialstandingoranyother factorimpactingontheselectionand/orevaluationofyourtender;

2.1.4 Youareorbecomeinsolventorhaveapetitionissuedagainstyou;

2.1.5 Youdonothavetheeconomicandfinancialstandingand/orthe technicalandprofessionalabilitytocarryouttheservices;

2.1.6 Youaresuspectedeitherdirectlyorindirectlyofbehavinginacollusive, canvassing,oranti-competitivemanneroryouofferoracceptan inducementorrewardinordertogainacommercial,contractual, regulatoryorpersonaladvantage;and/or

2.1.7 You(orifyouareacommercialentity,adirectororpersonwhohasthe powerofcontrolorpowertomakerepresentationsordecisionsonyour behalf)havecommittedanyoffencerelatingtoconspiracy,corruption, bribery,fraud,moneylaunderingoranyothercriminaloffencerelatedto yourcourseofbusinessorprofession

2.2 Nestareservestherightinitsabsolutediscretionto:

2.2.1 Refuseanytendersubmitted;

2.2.2 Disqualifyanypotentialtendererwhohasbeenconvictedofanyofthe offenceslistedatRegulation231ofthePublicContractsRegulations 2006;

223 Extendthetimeordateforfixedsubmission Insuchcircumstances Nestawillendeavourtonotifyalltenderersofanychange;

2.2.4 AmendanyaspectofthisITT(includingbutnotlimitedtotheevaluation criteriaandthetimeline)orceasetheprocessatanytime;

2.2.5 Negotiatetheawardofadditionalserviceswhicharearepetitionofthe servicesadvertisedinthisInvitationtoTendertothesuccessfulbidder;

226 Limitthenumberofproposalsinvitedtoparticipateinanyfollow-up activity(forexample,interviews)ortodispensewithanyfollow-up altogether.MeetingswilltakeplacevirtuallyorinLondonatouroffices (subjecttoCovidrestrictionsandHMGovernmentguidance);and/or

2.2.7 Requirethatyouclarifyyourtenderinwritingand/orprovideadditional informationand/oradequatereferencestoNesta’ssatisfaction Afailure torespondadequatelymayresultinyounotbeingselected

3.TendererResponsibilities

31 Youshallberesponsibleforallofyourowncosts,expensesandlosses whichmaybeincurredinrelationtothepreparationofyourtender, attendanceatinterviews,sitevisitsorsimilar.

3.2 YoushallatalltimestreatthecontentsofNestadocumentationas confidential,aswellasanyinformationregardingNesta(oranythird party)impartedtoyoubyanyothermeans,andonlydisclosesuch informationasmaybenecessaryforthepreparationofacompliant response.AtNesta’srequestyoushallreturnordestroyalldocuments, othermaterials,workingpapersrelatingtothisITTandallcopiesthereof includingallelectroniccopies Whencompletedyoushallconfirmsuch toNestainwriting

3.3 YoushallnotbeforethedateandtimespecifiedwithintheITT documentationdisclosetoanypersontheamountofyourproposal exceptwherethedisclosureinconfidenceisnecessarytoobtain insurancepremiumsorguaranteesrequiredaspartofanyproposalto Nesta.

3.4 AnycontractenteredintoasaresultofthisITTwillbeonNesta’s standardtermsandconditions(copyavailableonrequest)

4.IntellectualProperty

4.1 AllintellectualpropertyrightsinthisITTandallmaterialsprovidedby Nestaoranythirdpartyactingonitsbehalfshallremainthepropertyof Nesta

4.2 Anyintellectualpropertyarisingoutoftheprovisionoftheservicesshall belongabsolutelyandexclusivelytoNesta.

5.Warnings/disclaimers

51 NothingcontainedinthisITToranyothercommunicationmadein respectofitbetweenNestaoritsrepresentativesandanypartywill constituteanagreement,contractorrepresentationbetweenNestaand anyotherparty.Fortheavoidanceofdoubt,receiptbyyouofthisITT

doesnotimplytheexistenceofacontractorcommitmentbyorwith Nesta(oranythirdparty)foranypurpose

5.2 TheinformationcontainedinthisITTdoesnotpurporttocontainallthe informationwhichyoumayrequire.WhileNestahastakenallreasonable stepstoensure,asatthedateofthisITTthatthefactscontainedinit aretrueandaccurateinallmaterialrespects,Nestadoesnotmakeany representationorwarrantyastotheaccuracyorcompletenessor otherwiseofthisITT.

5.3 Nestaacceptsnoliabilitytoyouwhatsoeverandhoweverarisingand whetherresultingfromtheuseofthisITT,oranyomissionsfromor deficienciesinit

6.Waiver

FailureorneglectbyNestatoenforceatanytimeanyoftheprovisionsoftheseterms andconditionsshallnotbeconstruednorshallitbedeemedtobe,awaiverofour respectiverightshereunder,norinanywayaffectthevalidityofthewholeoranypart ofthisagreement,norprejudiceourrespectiverightstotakesubsequentaction.

7.Jurisdiction

ThisITTshallbegovernedbyandinterpretedinaccordancewiththelawsofEngland andWalesandsubjecttotheexclusivejurisdictionoftheEnglishcourts.

Appendix2DiscoveryAwardcohortJune2023May2024

● A.D.A, SheffieldHallamUniversityUK.A.D.A.isawearablepersonalisedaid thattracksdailymovements,providingdigitalfeedbacktohelppreventfalls

● AIInteractionAdvisor,AmicusBrainInnovationsUSA Aninteractivevoice andtext-assistivedevicethatcanhelpwith‘brokenspeech’andonline communication,promotingdigitalinclusionforpeoplelivingwithdementia.

● AI-baseddigitalhealthsystem,KITE-TorontoRehabilitationInstitute Canada).ApreventativeAI-baseddigitalhealthsystemthatcandetectand respondtoriskybehaviour,limitingthechanceofinjuriesforthoselivingwith dementia

● AIDEAIforDementiaEmpowermentandEngagement),MiiCareUK.This virtualvoicecompanionoffersdigitalinterventionssuchasamedicinesensor (confirmingwhenandwhichmedicinehasbeentaken)tosupportgeneral health

● AI-enabledpersonaliseddigitalreminiscenceplatform,MemoryLaneGames IsleofMan).ThisAIgame-likesoftwarepromotespositivesocialexperiences thatcanhelpdelaydeclineinbrainfunction.

● AUTONOMOUS,AssociaçãoFraunhoferPortugalResearchPortugal).An AI-systemthatcanbeintegratedintoexistingtechnologiessuchassmart watchestooffercommunicationassistanceforpeoplelivingwithdementiaand prolongindependentlivingathome

● Biodynamiclighting/sensing,SkyjoyLtd.UK.Biodynamiclightingsimulates thesun’sdailycycle,easingsundowningsymptoms(restlessness,agitation, irritabilityorconfusionthatcanworsenasdaylightfades)andimproving generalwellbeing

● CLEARAI,UlsterUniversityUK Adigitalplatformthatmonitorsdailyroutines, collectingdatatoidentifytriggersofagitationandthenrespondwith interventionstomitigatethese.

● CrossSense,AnimorphCo-operativeUK.Awearableaugmentedreality cognitiveaidthatcombinessensoryinputs(suchassoundandsight)tohelp slowmemorydeclineandimproverecall

● CUE D,NorthumbriaUniversityUKwithUniversityofTorontoCanada) A machinelearningandartificialintelligencedevicethatflagswhensomeonehas losttrackofataskthroughbehaviouralandphysiologicalindicators,then providestherelevantcuestogetthembackontrack.

● DAWN,CircadianLightingLtd,UK AreplacementlightbulbthatusesAI learningpatternstodetectdeteriorationsinbehaviour Thebulbalsoprovides optionalreminderstohelpwithdailyactivities,lesseningcaregivers’workload andhelpingpeoplelivingwithdementiamaintainindependence.

● DementiaConnect,CardiffMetropolitanUniversityUK.Amobileapp-based solutionthatcreatespersonaliseddigitalinterventionstohelpalleviate

sundowningsymptoms(restlessness,agitation,irritabilityorconfusionthatcan worsenasdaylightfades)

● eargym,eargymUK Ahearingmonitorforpeoplelivingwithdementiatohelp themretaintheirphysicalhealthandindependenceforlonger.

● Earlydetectionchangesinthesymptomsofdementiaforeffective interventionsforsundowning,SocialCareInstituteforExcellenceUK.Home basedtechnologythatmonitorsaperson’sdailyroutine,tospotearlysignsof sundowningandprovideinsightstosupportinterventions

● Gerty,SupersenseTechnologiesLtdUK.A4G-enableddigitalhubplacedin thehomeofapersonlivingwithdementia,enablingthemtoconnectwith caregiversandfamily,andmaintaintheirindependenceforlonger.

● iMAGIC,KhalifaUniversityUnitedArabEmirates).iMAGICsmartglassesoffer variousassistivefeaturesthatincludefacialrecognition,remindersandalerts, zoominginandouttofacilitatenavigation,phonecallstolovedonesandvital signmonitoringtoassistpeoplelivingwithdementiaintheireverydaylife.

● LiveFree,UniversityofEdinburghUK.Asensorsystemthatmonitorseveryday routines,providinginterventionsandsuggestionstohelpguidepeopleliving withdementiaintheirdailyactivity

● LUC101,LUCIDIncCanada) LUC101isasystemthatofferspersonalised musicsessionsdesignedtoeaseanxietyandagitationforpeoplelivingwith dementia.

● MarrAssist,OliveAILimitedUK.ApersonalisedAI-poweredavatar(icon representingaparticularperson,basedonalovedone)thatprovidesreminders andpromptstohelppromoteindependence

● MemoryAId,TheMARCSInstitute,WesternSydneyUniversityAustralia) A tailored,multi-componenthomeassistantthathelpswithdailyactivities throughremindersandpromptsforpeoplelivingwithdementia.

● PORTAD,LaGuapaMediaColombia).Animmersive,virtual-realityexperience thatsimulatestherapeuticandfamiliarenvironmentswithbreathingtechniques, easinganxietyandagitationexperiencedbypeoplelivingwithdementia

● SimonCareManagement,SimonCareManagementCorporationUSA.A personal,AI-basedmobileappthatusesgeo-trackingtolearnthespecific needsofapersonlivingwithdementiaandofferrelevant‘nudges’tosupport dailyactivities,includingremindingindividualsofaPINwhentheappdetects theyareatthebank

● TheDorothyCommunity,CareCityCIC,UK Adigital“yellowbrickroad”app thatoffersdirectionsviacolourfularrowsandpathwaysonthescreen,helping peoplelivingwithdementianavigatetheirareaindependently.

● Theora360,ClairvoyantNetworks,IncUSA.Theora360isaremote monitoringsystemthatusessensorstoprovideinsightintobehaviouraround fallstohelpwhencaregiversarenotpresent,ensuringsafetyand independence.

Appendix3Non-financialsupportdeliveredintheDiscoveryPhase

BelowsummarisestheNFSprogrammethathasbeendeliveredbetweenJune2023 andMay2024fortheDiscoveryPhase Themajorityofactivitieswereconducted virtuallytoensuretheinternationalcohort24teams)couldaccesstheinformation andsupportequally.

Accesstousers

Duringthediscoveryphaseinnovatorswereconnectedwithaninternationalcohort ofdementiaorganisationsAlzheimer'sSociety,CentreforAgingandBrainHealth InnovationCABHI,andDementiaAustralia),toreceivedirectaccesstopeopleliving withDementiaandtheircarers.Onlinefocusgroupswererunin-personand virtually.

Discoveryevents

Onboarding& CommunicationsWorkshop

Co-creationWorkshop

Socialconnectednessand technologyfeatures

Thisworkshopconsistedofanoverviewofwho weareandthetimelineoftheprize,aswellasan in-depthguideintohowtocreatemessaging, brandingandsocialmediacampaignsforyour work.

Thisworkshop,runalongsidetheRoyalCollegeof Art,providedanintroductiontoco-designanda discussionabouthowco-designcouldbeapplied withinthedementiasetting

CentreforAging+BrainHealthInnovation CABHI’sSeniorAdvisoryPanelhostedawebinar fortheLongitudePrizeonDementiacohorttofind outmoreaboutsocialconnectednessandhowto considerfunctions/featuresintheirsolutionsthat directlyorindirectlyreduceisolation/increase connection

Thewebinarincludedadiscussiononthe importanceofsocialconnection,theimpactof socialisolation,andanintroductiontothesocial connectednesschecklistasatooltoinform innovators

Eventscontinuedbelow:

Innovatewithdata responsibly

GenAIinHealthandSocial Care,hostedbyMicrosoft

Go-tomarketstrategiespanel event

Paneldiscussiononproduct developmentandco-designin health-tech

Masterclass:Go-tomarket strategies

Workshop:HowToGetFree Scale-UpSupportfromSAP andEY,viatheTRANSFORM SupportHub

DataandAIisdrivingthenextwaveofdigital transformationhelpingorganisationsreimagine theircustomerexperiencesanddrivingoperational efficiencies.Dataprivacyandsecurityisbecoming atoughchallengefordata-drivenorganisations today Inthissession,AWScoveredhowdatais helpingorganisationsinnovateandreimaginetheir business.Thesessionexploredthekeydata securityandgovernancerelatedchallengeslarge organisationsfaceastheyundergodata-driven transformationjourneys Theyalsosharedbest practice,guidancetogetpeople,processand technologyrighttocombatthesethreatsand adoptmoreresponsiblepractices.

Microsoftshowcasedtheirvariousprograms designedtosupportandempowertechstart-ups. Theydiscussedhowtheycanhelppartnersbuild solutions,go-to-marketandco-sellwithMicrosoft, plusconsiderhoworganisationsareusingGenAIin healthandsocialcare.

Differentperspectivesongo-to-marketstrategies inthehealth-techindustry.

Keylearningsfromhealthtechentrepreneurson productdevelopmentandco-design.

● Mastergo-to-marketessentialsforhealth techsuccess.

● Learnhowtonavigateregulationsfor seamlessmarketintegration

● Findouthowtoleveragetechandanalytics foreffectivemarketpenetration.

● Startmeasuringsuccess,anditerating strategiesbasedonfeedbackfor acceleratedgrowth

LivedemoandQ&Awithpartnersatthe TRANSFORMSupportHub anonlineportal whereDiscoveryTeamscanconnect(forfree)with skills-basedvolunteersfrommajorcorporations likeSAPandEY,newcorporatesales opportunities,andevencoursesandtemplates relatedtointernaloperations

Dataandtechnologysupport

SocialTechTrustworkedwithChallengeWorkstosupportallteamswiththeir uniquedataandtechchallenges.Throughacombinationof11mentoring,expert masterclassesandworkshops,SocialTechTrustworkedtounderstandinnovator techanddataneedsandassistedtheminrefiningyoursolutionstohelpyou maximisebeingpartoftheLongitudePrizeonDementiacohortintheDiscovery Phase.

Fourtechspecialistassociateswereavailableforeachteamtobook11specialist support(focusedoneachteam’sparticulardataandtechneeds) Thissupportwas providedinadditiontogeneraltechanddatasupportfromotherexperts.

Dementiaexpertpool

Teamscouldselectandbook1-to-1sessionswithexternalexpertsonarangeof topicsrelevanttotheirdevelopment.Expertiseincludedfrontlinedementiacare, co-design,healthcaredesign,businessdevelopmentandcommercialisation,AI specialists,entrepreneursinassistivetechnology,datascienceandmarketing

Externalevents(in-personandonline)

● HealthyAgeingConference,InnovateUK,London,UK

● LongitudePrizeonDementiashowcase,Alzheimer’sSocietyFundraising event,London,UK

● Alzheimer’sDiseaseInternationalADI36thGlobalConference,Krakow, Poland