North Carolina Pharmacist Volume 106 Number 2 by North Carolina Association of Pharmacists

Call For Articles

North Carolina Pharmacist (NCP) is now accepting articles for publication consideration. As a peer-reviewed publication, NCP aims to inform, educate, and inspire pharmacists— from students and residents to seasoned practitioners— as well as pharmacy technicians in all areas of practice. We welcome a wide variety of submissions, including original research, quality improvement initiatives, medication safety, case reports or case series, reviews, clinical pearls, unique business models, technology innovations, and opinion pieces. Articles authored by students, residents, and new practitioners are encouraged, and mentors and preceptors are asked to guide their mentees and students in submitting appropriate written work for publication. The Author Instructions have been updated to clarify formatting requirements, improve guidance on referencing, and streamline the submission process. Key changes include a submission disclosure statement and notices regarding the appropriate use of AI. Authors are encouraged to review the complete instructions before submitting to ensure compliance with the new policies. Don’t miss this opportunity to share your knowledge and contribute to the advancement of pharmacy in North Carolina. For details on formatting and article types, click Guidelines for Authors, and for questions, please contact Tina Thornhill, PharmD, FASCP, FNCAP, Editor, at tina.h.thornhill@gmail.com.

Official Journal of the North Carolina Association of Pharmacists

PO Box 58

36 Court Square, SW

Graham, NC 27253

Phone: (984) 439-1646 www.ncpharmacists.org

EDITOR-IN-CHIEF

Tina Thornhill

LAYOUT/DESIGN

Rhonda Horner-Davis

EDITORIAL BOARD MEMBERS

Anna Armstrong

Jamie Brown

Lisa Dinkins

Jean Douglas

Brock Harris

Amy Holmes

John Kessler

Angela Livingood

Bill Taylor

BOARD OF DIRECTORS

EXECUTIVE DIRECTOR

Penny Shelton

PRESIDENT

Tom D’Andrea

PRESIDENT-ELECT

Leigh Foushee

PAST PRESIDENT

Bob Granko

TREASURER

Ryan Mills

SECRETARY

Macary Marciniak

Cassey Zendarski, Chair, SPF

Micaela Hayes, Chair, NPF

Lisa Dinkins, Chair, Community

Trent Beach, Chair, Health-System

Aparna Krishnamurthy, Chair, Chronic Care

Glenn Herrington, Chair, Ambulatory

Angela Livingood, At-Large

Elizabeth Locklear, At-Large

Leslie Barefoot, At-Large

North Carolina Pharmacist (ISSN 0528-1725) is the official journal of the North Carolina Association of Pharmacists. An electronic version is published quarterly. The journal is provided to NCAP members through allocation of annual dues. Opinions expressed in North Carolina Pharmacist are not necessarily official positions or policies of the Association. Publication of an advertisement does not represent an endorsement. Nothing in this publication may be reproduced in any manner, either whole or in part, without specific written permission of the publisher.

North Carolina Pharmacist

CORRECTIONS AND ADVERTISING

The energy, camaraderie, and palpable excitement generated at this year’s annual convention was truly magnificent. Although exhausted and weary from what had been a busy six months of advocacy work, as well as from the preparation for an anniversary convention, as your Executive Director, I felt, and still feel, as though I am on Cloud 9. As we gathered in the city of Asheville to celebrate 25 years of pharmacy unification, the event was made even more special because profession-altering legislation was being passed at the same time. The nostalgia surrounding 25 years of our history combined with the hope and thrill of a brighter future for our profession brought tears and jubilant cheers and applause to our Gala and Awards Ceremony. For many in the room, we had been advocating and waiting for years, even decades, for some of the changes to be made possible by the passing of House Bill 67. Others, particularly community pharmacy owners, had been fighting and praying for years for the reformation passed in the PBM Senate Bill 479. The NCAP staff and lobbyists have worked tirelessly to shoulder the battles, alongside our members, to get these two massive bills across the finish line. What makes these feats even more impressive

Penny S. Shelton, PharmD, FASCP, FNCAP

is that pharmacy saw more legislative victories this year, than in any other year in our history; and it was done in a year in which the General Assembly heard and passed a very small percentage of bills.

If you were not with us in Asheville, well I’m sorry that you missed out. During the gala, I remarked that those in the early years of their career could mark this moment in time as historical. The ability to tell future generations, I was there—I was in the room—when it happened, will be meaningful to you! There are not a lot of great profession-based historical moments that generate hallmark points-in-time for one’s career, but this 2025 Convention will become one.

I started thinking back over my career, I remember: a) the launching of the Asheville Project; b) the passing of the original collaborative practice and the beginning of Clinical Pharmacist Practitioners in our state; c) the creation of NCAP from the unification of all the previous separate organizations in our state; d) the passing of the original immunization bill; and e) the passing of our public health bill that gave pharmacists the ability to provide birth control, HIV PEP, and tobacco cessation care. All these historical moments remain important parts of our practice evolution; but with the passing of H67, we now enter a new and elevated era for our profession. In addition, the passing of S479 brings reform to help with the sustainability of pharmacies. Pharmacies have for far too long been

used and abused by PBMs to fuel their greed. For the first time, in a long time, there are some rays of hope shining among our pharmacy managers and owners.

The passing of H67 will also help with pharmacy sustainability. The bill amends the insurance statutes to clearly identify pharmacists as healthcare providers and requires health plans to pay pharmacists for the provision of healthcare services within their legal scope of practice. In addition, the changes to the existing collaborative practice statutes will bring much greater flexibility to expand collaborative practice into all practice settings and permit services that were not previously allowed. H67 also authorizes pharmacists for the treatment of influenza.

The enactment of the provisions within these two important bills requires many steps. NCAP is now working with stakeholders on processes, rules, protocols, resources, and we are working to outline programming that will assist pharmacists with implementation. The first step that we all need to take together is to help make pharmacists aware of the changes and new opportunities. On August 24, 2025, NCAP will provide a webinar that will review the implications and opportunities afforded by the passing of H67. I hope you will join us to catch some of the resolute hope that permeated the halls of our Annual Convention. Please enjoy perusing the content of this post-convention issue of our journal!

Dr. Ty Chapman is the 2025 Executive Fellow at the North Carolina Association of Pharmacists (NCAP) and a recent graduate of the UNC Eshelman School of Pharmacy. Originally from Westerville, Ohio, Ty moved to North Carolina with a mission to build community and advocate for a more just, patient-centered healthcare system. Throughout pharmacy school, Ty was deeply involved in service and advocacy. As a member of the Student National Pharmaceutical Association, he led an oral history workshop at the Conetoe Family Life Center Summer Camp in Edgecombe County, where he taught children how to conduct interviews, ask powerful questions, and explore the stories of healthcare pioneers from Eastern North Carolina. The goal: to inspire a new generation of leaders grounded in community and storytelling. A pivotal point in Ty’s advocacy work came when he collaborated with NCAP as a student working directly with Dr. Penny Shelton and NCAP’s Webmaster, Grant Ell, to develop an accessible PBM reform resource. This tool aimed to help pharmacists, patients, and politicians across North Carolina better understand the role of pharmacy benefit managers and support

meaningful policy change through education and grassroots engagement.

Ty’s passion for amplifying underrepresented voices also extends into his writing. He contributed a personal piece titled “Identity” to ASHP’s Hidden Narratives series, where he reflected on genealogical research that uncovered a surprising connection; his great-great-grandfather was a historic figure in Ohio’s pharmacy history. Ty also brings advocacy and art together through poetry, including a creative response to the APhA and AACP’s stance on the AMA’s article about “scope creep,” using humor and metaphor to reframe the narrative around pharmacists’ evolving roles.

Ty holds a Bachelor of Science in Pharmaceutical Sciences from The Ohio State University, with a minor in African and African American Studies. His professional path has been shaped by experiences at places like Health Park Pharmacy in Raleigh, where he found his voice as a student pharmacist advocate and learned firsthand the value of independent pharmacy in patient care and community health.

In addition to his work in pharmacy, Ty finds joy in reading science and historical fiction, kayaking, lifting weights, biking, and writing poetry. He also serves as a coordinator for the Marian Cheek Jackson Center’s Northside Residential Fellowship and Linking Generations program, where he promotes intergenerational connection and community wellness through oral

history and social justice work. Ty applied to this fellowship to continue serving the pharmacists and patients of North Carolina, to advocate for their needs, learn from their lived experiences, and uplift their stories, using both policy and creativity to build a healthier, more equitable future.

NCAP is proud to welcome Dr. Ty Chapman as our 2025 Executive Fellow!

2530 Professional Road Suite 200 North Chesterfield, Virginia 23235

Toll Free: (866) 365-7472

www.medicationsafety.org

Dr. Ty Chapman

Expert coverage for experts like you.

Taking care of others is what you do. But even the best caregivers need looking after, too. That’s where the insurance experts at Pharmacists Mutual come in.

As a pharmacist, you hold an esteemed position in your community. People rely on you for your expert advice, unique knowledge, and experienced opinions. But by the very nature of your profession, you can become a natural target.

That’s why, with more than 110 years of experience, more pharmacists depend on Pharmacists Mutual for the added insurance protection and coverage they need to carry out their critical work.

Respiratory Readiness: The Latest on the Respiratory Syncytial Virus (RSV) Immunization

By Kasey Holder, PharmD/MSPH Candidate

Introduction

As respiratory pathogens continually adapt, it is essential for healthcare professionals to stay up to date on the latest prevention, diagnostic, and treatment recommendations. Vaccines remain one of the most powerful tools in the prevention of respiratory illnesses, significantly reducing the burden of disease, hospitalizations, and mortality across vulnerable populations. Among the most impactful preventable respiratory infections is the respiratory syncytial virus (RSV). The Advisory Committee on Immunization Practices (ACIP) plays a central role in evaluating medical literature and providing expert recommendations to the Centers for Disease Control and Prevention (CDC) regarding best practices for vaccinations. Below is an overview of the impact of this infection, followed by a summary of the latest updates and recommendations for RSV.

Overview

RSV has become a major public health threat in the United States (US), with its biggest impacts on young children, older adults, and immunocompromised individuals.

The CDC estimates that RSV is the culprit for at least 100,000 hospitalizations annually for adults ≥ 60 years of age. Additionally, 80,000 children are hospitalized each year, and ≥ 2 million children visit a healthcare provider outpatient due to RSV annually. (1)

RSV is spread through surface contamination, respiratory droplets, and close contact with infected individuals. It’s season persists in the US from September to April, with a peak in the winter months. (2) Symptoms range from mild to severe, with infants and older adults being at the highest risk of more severe symptoms. Classic symptoms of RSV include rhinorrhea, cough, sneezing, wheezing, shortness of breath, and fevers. Based on these symptoms, it is crucial that RSV is considered in the differential diagnosis for patients presenting with cold or flu-like symptoms. RSV also has the potential to exacerbate heart failure (HF) and chronic obstructive pulmonary disease (COPD) in older adults, as well as asthma in children. (2)

At present, there is no specific antiviral therapy approved for the

treatment of RSV. Administration of ribavirin may be considered in cases of documented infections in severely immunocompromised patients. Management remains primarily supportive, focusing on symptom control. This may include oxygen, IV fluids, antipyretics, and mechanical ventilation to assist with breathing. (1,2) Antibacterials have no role in the treatment of RSV.

Prevention Updates

Unlike other infections, there is currently no immune marker or antibody threshold that predicts protection against severe RSV disease, and naturally acquired immunity after infection is likely to be limited and transient. (3) Current strategies for immunization focus on preventing severe disease in patient populations at the greatest risk: older adults and newborns. (4)

Vaccines for older adults. Given RSV’s high transmissibility, immunization is critical in preventing RSV hospitalizations and death. The CDC estimates that up to 800 deaths from RSV are prevented for every one million RSV vaccinations

given to older adults. (1,2)

Prior recommendations for administering the RSV vaccine to older adults included using shared decision-making between the patient and provider for adults aged 60 years and older. (4) On August 6, 2024, the ACIP revised recommendations to include a single dose of RSV vaccine for adults ages 60–74 only if at increased risk of severe RSV disease, and for everyone 75 years or older. (5) In its most recent update as of June 25, 2025, the CDC, following ACIP guidance from April 2025, now recommends a one-time dose of the RSV vaccine for adults aged 50–59 who have risk factors for severe RSV disease. (6) These risk factors included chronic cardiovascular, liver, hematologic, or respiratory diseases, end-stage renal disease or dependence on hemodialysis or other renal replacement therapy, diabetes mellitus with associated complications, neurologic or neuromuscular conditions causing impaired airway clearance, severe obesity, and specified moderate/ severe immune-compromising conditions. The ACIP stated the changes were intended to maximize vaccination in persons most likely to benefit. Additional consideration was given to the post-licensure safety surveillance data on the incidence of Guillain-Barré syndrome (GBS) after protein subunit RSV vaccination prior to October 2023 (2.30 [95% CI: 0.39-13.72] and 4.48 [95% CI: 0.88-22.90] for Arexvy® and Abrys-

vo®, respectively). (7) Vaccine-attributable cases (range) were estimated to be 3(0-10) and 16(329) per million doses administered to those 60 years of age and older. (5) Based on these numbers, the ACIP determined there is inconclusive evidence that there may be an association between GBS and the RSV vaccination. Such safety surveillance after Moderna mResvia® vaccination was not available at the time the recommendations were published. (5) In addition, it was thought that implementation barriers associated with the previous shared clinical decision-making recommendation would be reduced by permitting qualified vaccinators to determine patient eligibility for RSV vaccination based on patient attestation of a risk factor and/or clinical assessment even in the absence of medical documentation of a named risk condition.

While all three FDA-approved RSV vaccines are ACIP-recommended, only Abrysvo® (Pfizer) is currently approved for administration to pregnant women. (5,7) (see Table 1)

nocompromised adults. Ongoing research demonstrates waning efficacy with each RSV season in adult patients, yet protection for at least two RSV seasons has been shown. (8,9) Further research is needed to evaluate the timing/ benefit of additional RSV vaccines in patients. (10) Of note, the mRESVIA® vaccination, which uses mRNA technology, demonstrated 50% efficacy after 18 months for preventing respiratory illness. The Avrexy® and Abrysvo® vaccinations had approximately 78% efficacy after two RSV seasons. (7,8) Despite this, individuals who received a second dose one year after the initial dose exhibited minimal therapeutic benefit when compared to individuals who received only one dose. (7,8,9)

Although administered any time of the year, the CDC recommends older adults receive the RSV vaccination in late summer through early fall. (10) RSV vaccines can be co-administered with other adult vaccines during the same visit. (9) Studies have shown that patients are more likely to experience an adverse reaction when

Additional data are needed on the duration of protection from RSV vaccination, the immune response after revaccination, and immunogenicity data in immu-

the vaccines are co-administered; however, these reactions are low in severity and may occur with the administration of only one vaccine. These adverse reactions may in-

Table 1. Comparison of FDA-approved RSV vaccines

clude headaches and injection-site reactions. (11)

Prevention in newborns. Most infants acquire RSV-specific antibodies transplacentally. This provides some protection that wanes over the first months of life. (12) Administration of RSV vaccine (RSVpreF, Abrysvo®) to pregnant women during the third trimester of pregnancy (32 weeks 0 days to 36 weeks 6 days gestation during RSV season) is intended to protect infants against RSV by transferring antibodies from the mother to the baby trans-placentally. These antibodies protect the neonate against RSV for approximately 6 months after birth. Two phase three trials established key efficacy and safety data of maternal vaccination. (13,14) Efficacy against RSV-associated severe medically-attended lower respiratory tract infection (MA-LRTI) was 82.4% (95% CI: 57.5–93.9) and 70.0% (95% CI: 50.6–82.5) at 90 and 180 days, respectively. (13)

In addition to maternal immunization, the administration of a monoclonal antibody against RSV given to infants right after birth or before the start of the RSV season provides passive immunity against RSV. Previously, palivizumab, a neutralizing monoclonal RSV antibody, required five monthly doses throughout the RSV season. However, expense limits its use to very high-risk infants and young children, mainly in high-income settings. (3) More recently, nirsevimab (Beyfortus®, AstraZeneca/Sanofi) is a recombinant monoclonal antibody administered intramuscularly as a single injection intended primarily to protect infants throughout their

first RSV season. Data from clinical trials indicate that nirsevimab has approximately 75% efficacy (95% CI: 49.6-87.1) in preventing lower respiratory tract infections related to RSV. (15) Serious adverse events were reported in 6.8% of infants who received nirsevimab versus 7.3% of infants who received the placebo. (15) Another study that evaluated the pharmacokinetic data for nirsevimab in infants with extreme prematurity, chronic lung disease, or heart defects displayed that nirsevimab continued to be efficacious in these special populations. (16) Specifically, a third study concluded that weight-based dosing of nirsevimab is appropriate in those populations as well. (17)

Currently, weight-based dosing of nirsevimab is recommended for neonates less than 8 months born to mothers who are unvaccinated with a maternal RSV vaccine during pregnancy. If a mother gives birth between October and March and does not receive the RSV vaccine between 32 weeks 0 days and 36 weeks 6 days, gives birth within 14 days of vaccination administration, or has an unknown vaccination status, infants qualify to receive nirsevimab (Beyfortus®). (18) Recommendations are to administer a dose shortly before the RSV season, or within one week after birth if born during October to March in most of the U.S. (19) Children eight months through 19 months of age at increased risk for severe RSV should receive nirsevimab shortly before the child’s second RSV season. This group includes children who have chronic lung disease of prematurity, severe immunosuppression, severe cystic fibrosis, and/or American Indian and Alaska Native children. (19) If a child was

born prematurely and has chronic lung disease, the dose would be recommended if diuretic therapy, supplemental oxygen, or chronic corticosteroid therapy was indicated within 6 months of the second RSV season. The American Academy of Pediatrics details severe cystic fibrosis as a child who is in the less than the tenth percentile or who fits the criteria for serious lung disease. (19) If nirsevimab is not available, palivizumab (Synagis®) may be indicated; however, it is not preferred over nirsevimab due to increased cost, decreased convenience, and lower potency. (18,19)

As of June 2025, clesrovimab (Enflonsia®) gained FDA approval as another monoclonal antibody against RSV for infants. It is expected to be available for order in July 2025 and stands out due to its fixed 105 mg dose, regardless of weight, unlike nirsevimab and palivizumab. Clinical trial data showed that clesrovimab reduced RSV-related hospitalizations by approximately 84% and was comparable to palivizumab in terms of efficacy and safety. (20)

The use of a combined strategy involving maternal vaccination and administration of monoclonal antibodies to the newborn may be considered in special circumstances. Nirsevimab may be considered for infants born to vaccinated mothers in rare circumstances. Infants born to mothers thought unable or unlikely to achieve an adequate immune response to RSV vaccination or reduced transplacental transfer of antibodies (e.g., individuals with immunocompromising conditions) may be considered for such a strategy. In

addition, infants undergoing procedures that may enhance antibody clearance (such as cardiopulmonary bypass or extracorporeal membrane oxygenation (ECMO), as well as those at increased risk for severe RSV infection) may also be considered for combination therapy. (21)

Conclusions

Healthcare professionals should work in tandem to provide optimal RSV vaccine recommendations, particularly for vulnerable and high-risk populations. The RSV vaccine has demonstrated proven benefits in decreasing mortality and hospitalizations. Currently, the RSV vaccine is recommended as a one-time dose in individuals who are high-risk and > 50 years, everyone > 75 years, and in pregnancy. Nirsevimab is a monoclonal antibody against RSV, which has shown efficacy in preventing hospitalizations and mortality related to RSV in infants. Remaining up to date with evolving guidance from the ACIP and CDC is essential for optimizing patient care and health outcomes.

Author: Kasey Holder is a 2026 PharmD/MSPH Candidate at Campbell University College of Pharmacy & Health Sciences. (kmpfaff0217@ email.campbell.edu)

Key Points:

• RSV vaccines prevent RSV hospitalization and death.

• RSV vaccines are currently given as a one-time dose in eligible adults.

• Adults < 50 years, unless

pregnant or high risk, are not indicated to receive the RSV vaccine at this time.

• Nirsevimab is a monoclonal antibody effective in preventing infant RSV-related hospitalizations.

vention. July 3, 2024. Accessed May 28, 2025. https://www.cdc.gov/vaccines/vpd/rsv/hcp/older-adults.html.

8. Katella K. Should you get an RSV vaccine? Yale Medicine. January 9, 2025. Accessed May 10, 2025. https://www. yalemedicine.org/news/should-youget-an-rsv-vaccine.

References

1. Surveillance of RSV. Centers for Disease Control and Prevention. Accessed May 10, 2025. https://www. cdc.gov/rsv/php/surveillance/index. html#:~:text=RSV%20burden%20 estimates,younger%20than%205%20 years%20old.

2. Clinical overview of RSV. Centers for Disease Control and Prevention. Accessed May 10, 2025. https://www. cdc.gov/rsv/hcp/clinical-overview/ index.html.

3. World Health Organization (WHO). WHO position paper on immunization to protect infants against respiratory syncytial virus disease, May 2025. Available at https://iris.who.int/ bitstream/handle/10665/381539/ WER10022-eng-fre.pdf?sequence=1 (accessed 6/3/25)

4. Melgar M, Britton A, Roper LE, et al. Use of respiratory syncytial virus vaccines in older adults: recommendations of the Advisory Committee on Immunization Practices—United States, 2023. MMWR Morb Mortal Wkly Rep 2023;72:793–801

5. Britton A, Roper LE, Kotton CN, et al. Use of Respiratory Syncytial Virus Vaccines in Adults Aged ≥60 Years: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2024. MMWR Morb Mortal Wkly Rep 2024;73:696-702. DOI: http://dx.doi. org/10.15585/mmwr.mm7332e1.

6. US CDC Accepts Ousted Vaccine Panel’s Recommendations for RSV, Meningococcal Shots. Reuters. Accessed July 9, 2025. https://reuters. com/business/healthcare-pharmaceuticals/us-cdc-accepts-rsv-recommendations-made-by-former-vaccinepanel-2025-07-02/.

7. Healthcare Providers: RSV vaccination for adults 60 years of age and over. Centers for Disease Control and Pre-

9. Soucheray S. Trial Shows Waning Efficacy of RSV Vaccine Across 3 Seasons in Older Adults. CIDRAP. April 22, 2025. Accessed May 20, 2025. https://www.cidrap.umn.edu/respiratory-syncytial-virus-rsv/trial-showswaning-efficacy-rsv-vaccine-across-3seasons-older.

10. Berg S. RSV Vaccines: Questions Patients May Have and How to Answer. American Medical Association. January 3, 2025. Accessed May 27, 2025. https://www.ama-assn.org/delivering-care/public-health/rsv-vaccinesquestions-patients-may-have-andhow-answer#:~:text=Will%20you%20 need%20to%20get,at%20least%20 two%20RSV%20seasons.

11. What to know about getting flu, COVID-19, and RSV vaccines at the same time. Centers for Disease Control and Prevention. November 2, 2023. Accessed May 27, 2025. https://www.cdc.gov/ncird/whatsnew/getting-vaccines-at-same-time. html#:~:text=Some%20people%20 may%20prefer%20to,would%20 be%20difficult%20for%20you.

12. Chu HY et al. Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh. J Infect Dis. 2014;210:582-9.

13. Simões EAF et al., MATISSE (Maternal Immunization Study for Safety and Efficacy) clinical trial group. Efficacy, safety and immunogenicity of the MATISSE maternal respiratory syncytial virus prefusion F protein vaccine trial. Obstet Gynecol. 2025;145(2):157-67. doi:10.1097/ AOG.0000000000005816.

14. Kampmann B et al. Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants. N Engl J Med. 2023;388:1451-64.

15. Hammitt LL et al. Nirsevimab for prevention of RSV in healthy latepreterm and term infants. N Engl J Med. 2022;386:837-46.

16. ESimões EAF et al. Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants,

and pharmacokinetic extrapolation to infants with congenital heart disease and chronic lung disease: a pooled analysis of randomised controlled trials. Lancet Child Adolesc Health. 2023;7(3):180-9. doi:10.1016/S23524642(22)00321-2.

17. Clegg L et al. Population pharmacokinetics of nirsevimab in preterm and term infants. J Clin Pharmacol. 2024;64:555-67.

18. Nirsevimab Administration. American Academy of Pediatrics. July 11, 2024. Accessed May 10, 2025. https://www. aap.org/en/patient-care/respiratory-syncytial-virus-rsv-prevention/ nirsevimab-administration/?srsltid=AfmBOorIyB5KODrSXVcX7xljQT1n3XfOWBkD8XsARBP38Tx6DAkx7W_C.

19. American Academy of Pediatrics (AAP). AAP Recommendations for the Prevention of RSV Disease in Infants and Children. Redbook Online. February 21, 2024. Available at https://publications.aap.org/redbook/resources/ pdfDownload/25379 (accessed 6/3/25)

20. U.S. FDA approves Merck’s ENFLONSIATM (Clesrovimab-CFOR) for prevention of respiratory syncytial virus (RSV) lower respiratory tract disease in infants born during or entering their first RSV season. Merck. June 11, 2025. Accessed June 12, 2025. https://www.merck.com/ news/u-s-fda-approves-mercks-enflonsia-clesrovimab-cfor-for-prevention-of-respiratory-syncytial-virus-rsv-lower-respiratory-tract-disease-in-infants-born-during-or-entering-their-fir/.

21. CDC. RSV Immunization Guidance for Infants and Young Children. Available at https://www.cdc.gov/ rsv/hcp/vaccine-clinical-guidance/infants-young-children.html (accessed 6/4/25)

Prioritizing Public Health:

Joining Forces Across Practice Settings for a Healthier North Carolina

The 2025 NCAP Annual Convention, held June 23–25 at the Crowne Plaza Asheville in Asheville, NC, brought pharmacy professionals together from across the state for two and a half days of continuing education, networking, and celebration. This year’s convention was especially meaningful as NCAP marked 25 years as a unified association.

Day One set the tone with a diverse selection of sessions addressing every practice area—opioid use disorder treatment, long-term care, health-system and hospital pharmacy, ambulatory care, and community pharmacy. Attendees connected with exhibitors and sponsors during lunch while also earning tickets for exciting prize drawings. Many took advantage of the photo booth to commemorate the 25th anniversary with colleagues and friends.

Day Two offered another robust schedule, including presentations on collaborative practice, population health, telehealth and technology, non-traditional practice settings, the essential contribu-

tions of pharmacy technicians, and emergency preparedness. The day concluded with the always-anticipated Gala and Awards Dinner, where attendees not only celebrated leaders in the profession but also the passage of long-awaited, profession-changing legislation— making the evening especially memorable.

Day Three wrapped up the convention with a half-day of hands-on instruction and workshops, including gluteal Z-track administration of LAIs, Medicaid provider enrollment and billing, and the latest immunization updates.

As the largest statewide event for pharmacy professionals, the Annual Convention continues to highlight the strength, innovation, and passion of North Carolina’s pharmacy community. NCAP extends deep appreciation to our speakers, attendees, exhibitors, sponsors, and everyone who contributed to this year’s success. Special thanks go to the Convention Planning Committee—Dave Phillips, Dustin Wilson, Dave Sugrue, Kaileigh Yen, Monica Dillingham, Carrie Baker,

Mina Wolfe, and Mackie King—and the 25th Anniversary Planning Committee—Ouita Gatton, William McSkimming, Grace Barr, and Betsy Abbot—for their dedication and vision.

Planning is already underway for the 2026 NCAP Annual Convention, with details and location to be announced soon. We look forward to welcoming you next year for another outstanding gathering of pharmacy professionals!

By The Numbers Milestone:

Honoring Excellence: 2025 NCAP Awards

The North Carolina Association of Pharmacists (NCAP) is proud to recognize the outstanding achievements and service of its members through the presentation of annual awards. These honors celebrate leadership, innovation, and dedication across all areas of pharmacy practice, as well as the invaluable contributions of students and technicians who strengthen our profession.

At the 2025 NCAP Annual Convention in Asheville, award recipients were recognized before colleagues, mentors, and friends. Each award carries a rich history — from the prestigious Bowl of Hygeia, honoring civic leadership, to the Don Blanton Memorial Award, recognizing advancement of pharmacy in North Carolina, to Academy-specific awards that spotlight excellence in practice settings such as ambulatory care, chronic care, and community care.

While some awards highlight lifetime achievement and service, others encourage new professionals and students to continue shaping the future of pharmacy. This year’s honorees represent a remarkable spectrum of leadership and dedication: seasoned pharmacists who have committed decades to patient care, rising stars who are already making significant impacts early in their careers, and technicians and students who are integral to the future of the profession.

NCAP also paused to reflect on the importance of collective recognition. In lieu of naming a single Health-Systems Pharmacist of the Year, the association honored all health-system pharmacists for their tireless commitment, paying tribute to Helene’s legacy and the enduring impact of those who serve in hospital and health-system practice.

Taken together, the 2025 award recipients exemplify the values that drive NCAP forward: service, innovation, leadership, and community. Their stories remind us that pharmacy is more than a profession — it is a calling to improve the lives of patients and to advance health for all North Carolinians.

Congratulations to each of this year’s awardees. Your contributions inspire us all.

2025 FNCAP Recipients

2025 FNCAP Recipient: Melissa “Lisa” Dinkins

NCAP proudly recognizes Melissa “Lisa” Dinkins, PharmD, BCPS, CPP, of Wingate, NC, as the 2025 FNCAP Award Recipient.

Dr. Dinkins serves as Director of Community Health Outreach and Professor of Pharmacy at Wingate University School of Pharmacy. She is widely respected for her leadership in community health and her dedication to educating future pharmacists.

Congratulations to Dr. Dinkins on this well-deserved honor!

2025 FNCAP Recipient: Tasha Woodall

NCAP is honored to recognize Tasha Woodall, PharmD, BCACP, CPP, of Horseshoe, NC, as a 2025 FNCAP Award Recipient.

Dr. Woodall serves as Co-Director of the MAHEC Center for Healthy Aging and Associate Professor of Clinical Education with the UNC Eshelman School of Pharmacy. She is celebrated for her commitment to advancing care for older adults and for her leadership in clinical education.

Congratulations to Dr. Woodall on this outstanding achievement!

2025 FNCAP Recipient: Jeff Reichard

NCAP is pleased to recognize Jeff Reichard, PharmD, of Cary, NC, as a 2025 FNCAP Award Recipient.

Dr. Reichard serves as Executive Director of Pharmacy, Acute Care & Supply Chain Pharmacy Services with UNC Health. He is recognized for his leadership in health system pharmacy, ensuring safe, efficient, and innovative care delivery across the state.

Congratulations to Dr. Reichard on this well-deserved honor!

Thank You to Our Sponsors and Exhibitors

Each year, NCAP’s Annual Convention comes to life not only through the energy and dedication of our members, but also through the incredible support of our sponsors and exhibitors. Their commitment makes it possible for us to provide high-quality continuing education, networking opportunities, and meaningful celebrations that strengthen our profession.

Our sponsors help us enhance programming, create engaging experiences, and recognize excellence in pharmacy. Our exhibitors bring innovation and resources directly to attendees, sparking conversations that extend far beyond the convention hall. Together, they play a vital role in ensuring our event is a success.

On behalf of the NCAP Board, staff, and members, we extend our heartfelt thanks to every sponsor and exhibitor who partnered with us this year. Your support not only enriches our convention, but also helps advance pharmacy practice across North Carolina. We are grateful for your continued investment in our profession and look forward to building on this collaboration in the years ahead.

Platinum Sponsors

Amgen

McKesson Amplify Merck

Novo Nordisk

Pharmacist Mutual Insurance Company

Rpharmy

Silver

Connecting Top Employers with Premier Professionals.

EMPLOYERS:

Find Your Next Great Hires

• PLACE your job in front of our highly qualified members

• SEARCH our resume database of qualified candidates

• MANAGE jobs and applicant activity right on our site

• LIMIT applicants only to those who are qualified

• FILL your jobs more quickly with great talent

PROFESSIONALS:

• POST a resume or anonymous career profile that leads employers to you

• SEARCH and apply to hundreds of new jobs on the spot by using robust filters

• SET UP efficient job alerts to deliver the latest jobs right to your inbox

• ACCESS career resources, job searching tips and tools NCAP CAREER CENTER

Poster Session: Abstracts

Poster 1

Title: Enhancing Harm Reduction: Lessons Learned from Partnering Syringe Service Programs with Community Pharmacies in North Carolina

Author: Cheryl Viracola, PharmD

Objective: From 2000–2023, over 41,500 North Carolinians lost their lives to drug overdose, with an average of 12 deaths daily in 2023. The CDC considers Syringe service programs (SSPs) evidence-based strategies for overdose prevention linked to a 50% reduction in HIV/ HCV incidence. They provide sterile injection equipment, syringe disposal, disease testing, education, and treatment referrals. North Carolina legalized SSPs in 2016 (G.S. 90-113.27), and today, 50 SSPs serve 62 counties. However, barriers such as limited geographic reach and operating hours persist. The North Carolina Association of Pharmacists (NCAP) received grant funding from the Governor’s Institute to explore pharmacies as SSP extension sites, aiming to improve access and reduce stigma.

Methods: NCAP recruited four SSPs and seven pharmacies across four counties to assess interest in collaboration. If both parties agreed, a virtual meeting was held to discuss implementation. A launch date was then set for supply handoff and distribution of educational materials. Each pharmacy tracked unique patients served, SSP kits distribut-

ed, and referrals made for additional harm reduction resources. Results: As of Q2 2025, the threeyear pilot has demonstrated the effectiveness of pharmacies as SSP extension sites, serving 433 unique patients, distributing 1,154 kits, and facilitating 176 SSP referrals— marking year-over-year increases of 260%, 319%, and 274%, respectively. Data collection is ongoing.

Conclusion: Community pharmacies have proven essential in expanding harm reduction services as SSP extension sites. All participating SSPs and pharmacies sustained and expanded their programs beyond the grant cycle. Further scaling efforts in high-risk counties could enhance access and impact.

Poster 2

Title: Community Pharmacy-Based Psychotropic Long-Acting Injectable (LAI) Service Reimbursement

Authors: Mina Wolfe, PharmD1; Jerry McKee, PharmD, MS, BCCP2; Vera Reinstein, PharmD, BCPS3

Institution: 1University of North Carolina at Chapel Hill, Chapel Hill, NC; 2North Carolina Association of Pharmacists, Durham, NC; 3Alliance Health, Morrisville, NC

Objective: Since October 1, 2021, North Carolina pharmacists have been authorized to administer long-acting injectables (LAIs) to adults with a prescription. However, few pharmacies currently provide this service. To address

this gap, the North Carolina Association of Pharmacists received a grant from Alliance Health to expand community pharmacy services that support individuals with serious mental illness and/ or substance use disorder. The first community pharmacy service studied is focused on improving access to LAI psychotropics, including antipsychotics and medications for opioid use disorder. The project aims to develop and present to payors a scalable, equitable, and sustainable payment model for pharmacy-based LAI administration. Additional objectives include increasing treatment capacity, reducing medication waste, and identifying patients who may benefit from LAIs due to challenges with oral medication adherence.

Methods: Nine community pharmacies across North Carolina were selected based on claims data and team interviews. After completing a live training webinar, participating pharmacies used an online platform to document time spent on LAI service components and ensure quality assurance. Tracked activities included obtaining informed consent, preparing materials and injections, assessing clinical appropriateness, administering the product, and communicating with providers (including follow-up for missed appointments). A micro-costing analysis is being conducted to inform payment model development based on time, service components, and personnel involved.

Results: Between June 1 and September 30, 2024, 614 LAI administration events were documented, exceeding the target of 500. Collected data and micro-costing analysis will inform the design of a viable payment model.

Conclusions: Community pharmacy-based LAI administration is an underutilized service with strong potential to improve outcomes for patients with serious mental illness and/or substance use disorder. This project demonstrates feasibility, highlights the need for sustainable reimbursement, and promotes pharmacist-psychiatrist collaboration—especially within telepsychiatry models—to enhance access and adherence to evidence-based treatment.

Poster 3

Title: Evaluating the availability of no-cost naloxone in Eastern and Southeastern Area Health Education Center (AHEC) Regions of North Carolina

Authors: Grace Marley PharmD, Caroline Shubel MPh, Bayla Ostrach PhD, MA, CIP, Delesha Carpenter PhD, MSPh

Introduction: High costs continue to limit naloxone accessibility for many patients, so pharmacists should know of local no-cost naloxone distributors. This survey aimed to identify and evaluate no-cost naloxone distribution in Eastern and Southeastern AHEC regions of North Carolina.

Methods: An online Qualtrics survey was distributed from June 2023 to January 2024 to all identified no-cost naloxone distributors

in North Carolina. A community advisory panel helped identify the contact list. The survey gauged program type, demographics served, and locations of naloxone distribution. Descriptive statistics and mapping functions were utilized to evaluate no-cost naloxone distribution.

Results: Fifty-one no-cost naloxone distributors were identified in Eastern and Southeastern AHEC counties (41, 10, respectively). Identified programs included: Health Departments (n=19), treatment programs/centers (n=10), syringe service programs (N=9), EMS/ Community Paramedicine/ Post Overdose Response Teams (PORT) (N=7), justice-involved programs (N=6), among others. Programs reported distributing no-cost naloxone often to non-Hispanic white (3.65, 0.69), Black (3.37, 0.81), and Hispanic or Latino (2.76, 0.93) populations, and less often to American Indian or Alaska Native (1.96, 0.84), and Asian populations (1.76, 0.86). Most programs reported distribution to people who use drugs (N=48) and individuals with a history of substance use disorder (N=48); fewer programs reported distributing to individuals leaving treatment/detox (N=34), and pregnant people who use drugs (n=38).

Conclusion: This research indicates no-cost naloxone distributors in Eastern NC are distributing less frequently to Native American or Alaska Native patients, pregnant people who use drugs, and individuals leaving treatment/detox; all populations at greater risk of overdose death compared to the overall population. Pharmacists should be aware of local no-cost naloxone distribution available to

patients and to whom programs distribute naloxone.

Poster 4

Title: Evaluation of the Impact of a Clinical Pharmacist on Primary Care Outcomes in a Behavioral Health Clinic

Authors: Brandon Montz, PharmD, Eric Metterhausen, PharmD, BCACP, BCPS, CPP, CPH Tara Huston, PharmD, Madeline Wright, PharmD, BCPS

Institution: Cherokee Indian Hospital Authority, Cherokee, NC

Objective: This quality improvement project aimed to evaluate the impact of a clinical pharmacist on primary care outcomes in a behavioral health clinic. Primary outcomes included change in the number of patients meeting evidence-based targets for A1c, blood pressure, and hepatitis C treatment. Secondary outcomes included the total number of pharmacist interventions, the number of patients achieving SVR12, and changes in average systolic and diastolic blood pressure.

Methods: This prospective time-series quality improvement project is expected to occur from January 2025 to June 2025. Clinical pharmacist encounters were initiated by direct discussion with providers or by a pharmacist consult service. The pharmacist conducted medication reviews, provided patient education, and offered therapeutic recommendations to improve quality and access to care. Baseline and follow-up data—including A1c, blood pressure, and medication therapy—were collected at visits occurring every 1–2

weeks or as clinically indicated. Follow-up continued until therapeutic stability, with outcomes assessed for up to six months.

Results: There were 93 patients identified in the first 3 months of this project whom required clinical pharmacist appointments, 39 (42%) had an initial pharmacist encounter. Common disease states addressed included hypertension (64%), diabetes (36%), and hepatitis C (33%). A total of 84 pharmacist interventions were made across 10 disease states, with hypertension (39%) and diabetes (14%) accounting for the most. Patients with controlled blood pressure increased from 8% to 28%. Mean blood pressure decreased from 143.1/86.6 to 126.3/77.5 mmHg (-16.8/-9.1).

Four patients-initiated hepatitis C treatment; three patients achieved SVR12.

Conclusion: Embedding a clinical pharmacist in a behavioral health setting can significantly improve primary care outcomes, especially for high-impact conditions such as hypertension and diabetes. The pharmacist’s role in medication management, patient education, and care coordination demonstrates value in bridging gaps between behavioral health and primary care.

Poster 5

Title: Assessing the Opportunity for Population Health Pharmacist-Led Deprescribing Among Medicare Advantage Value-Based Patients with Polypharmacy Concerns

Authors: Amanda Bonney,

PharmD; Molly Hinely, PharmD, BCPS; Anna Everhart, PharmD, BCACP; Angie Lynch, PharmD

Institution: Atrium Health Wake Forest Baptist, Winston-Salem, NC

Objective: To conduct a quality improvement project that assesses patient, provider, and medication characteristics to identify impactable patients and to reduce the use of multiple anticholinergics (Poly-ACH) and concurrent use of opioids and benzodiazepines (COB) among Medicare advantage (MA) populations.

Methods: A retrospective chart review of MA patients identified as having poly-ACH and COB gaps was completed. Inclusion criteria aligned with the Centers for Medicare and Medicaid services (CMS) poly-ACH and COB measures, which identify patients 65 years and older with multiple fills of unique anticholinergic medications and concomitant benzodiazepine and opioid prescriptions, respectively. Patients were excluded and determined to be non-impactable if both offending medications were managed by psychiatry, residing in long term care, or under hospice care.

Results: A total of thirty-five patients were at risk of failing the poly-ACH measure with 40% of them having opportunities for pharmacy teams to make interventions. A total of sixty-nine patients were at risk of failing the COB measure with 43% of them impactable. Majority of the patients had at least one of the offending agents prescribed by a specialist with less than half of patients with both medications prescribed by primary care. The most common

anticholinergic medications were cyclobenzaprine, hydroxyzine, and paroxetine. The most common COB combinations were hydrocodone and alprazolam, oxycodone and clonazepam, and tramadol and clonazepam.

Conclusions: The results of this study identified opportunities for population health pharmacy teams to proactively impact polypharmacy by working with IT staff to implement a best practice advisory within the EHR to alert the provider when a patient may be on multiple anticholinergic medications or concomitant benzodiazepines and opioids. Additionally, the pharmacy population health team will continue to evaluate a reactive workflow to make interventions related to deprescribing and medication optimization for this at-risk population.

Poster 6

Title: Evaluation of Tobacco/Nicotine Use Disorder Interventions Including Use of Guideline Directed Medications

Authors: Jada Abrams, PharmD Candidate, Pete Koval PharmD, BCPS, CPP

Institution: Cone Health; UNC Eshelman School of Pharmacy

Objective: The primary objective of this study was to examine the utilization of nicotine replacement therapies (NRT), varenicline, bupropion, nortriptyline, and motivational counseling among current and former smokers. Secondary objectives included assessing the accuracy of patients’ smoking status in their EPIC problem lists and if patients were referred to the

clinic’s clinical pharmacy practitioner (CPP) within the past year.

Methods: Medical records of 1,012 eligible patients seen at Cone Health Family Medicine Center between January 1, 2023, and August 2024 were reviewed. Patients were excluded if they were under 18 years old, had never smoked, were passive smokers, or were former smokers who quit prior to January 1, 2023. A former smoker was defined as someone who had quit smoking for six months or more. Data collected included medication use from fill histories, smoking status listed in problem lists, documentation of counseling in appointment notes, and referrals to the clinic’s CPP.

Results: Approximately 390 patients (39%) had either missing or incorrect smoking status documented in their problem lists (e.g., listed as current smoker despite meeting criteria for a former smoker). Among all pharmacologic agents used, the nicotine patch was the most prescribed for both current and former tobacco users. Notably, 650 patients (64%) were not receiving any smoking cessation therapy. Additionally, 22% of patients had an appointment with the CPP within the past year for smoking cessation support.

Conclusion: Smoking status should be reviewed and updated at every patient visit using a structured framework (e.g., the 5 A’s) to guide interventions. Identification and intervention in patients with tobacco use disorder offers an opportunity for pharmacists to play a role in smoking cessation through pharmacotherapy selection, personalized quit plan development,

and ongoing follow-up. Increased referrals to the clinic’s CPP may enhance smoking cessation outcomes.

Poster

Title: Pharmacy student-led health education outreach improves knowledge and behavior change motivation for prevention of type 2 diabetes among an undergraduate college community.

Authors: Dylan Hagen, Farah Sayed, Lisa Cale, Daniela Alejandra Vega, and Amie J. Dirks-Naylor

Institution: Wingate University School of Pharmacy, Wingate, NC

Objective: The purpose of this study was to determine if a pharmacy student-led educational intervention regarding type 2 diabetes prevention could improve knowledge and behavior change motivation in an undergraduate college community.

Methods: Five Doctor of Pharmacy students led an interactive campus-based educational session to raise awareness about type 2 diabetes. Knowledge and intent to adopt healthier lifestyle habits were assessed via pre- and post-surveys, with a ~2-month follow-up survey evaluating retention and behavior change. Participants were recruited through various student campus groups. A 30-minute Google Slides presentation covered topics relating to prevention of type 2 diabetes. Embedded video clips provided a virtual campus tour, highlighting locations such as the recreation center and cafeteria to demonstrate lifestyle

strategies and the Plate Method. Interactive questions encouraged participant engagement throughout. All surveys included 13 knowledge-based questions; post- and follow-up surveys also included 7–8 Likert-scale items on behavior change. A paired t-test compared mean knowledge scores between pre- and post-surveys. ANOVA with Tukey’s post-hoc test analyzed knowledge differences across all three time points among participants who completed all surveys. Data are presented as mean ± SD.

Results: 64 college students completed the pre and post-survey, with 17 completing the follow-up survey. The interactive educational session improved the knowledge of type 2 diabetes, evidenced by the improvement of scores between the pre-and post-surveys (7.0 ± 1.6 vs. 9.7 ±1.4, respectively; p-value <0.001). Knowledge was retained as shown by the results on the follow-up survey (6.4 ± 1.6, 8.7 ± 1.7, vs 9.9 ± 5.1, pre-, post-, follow-up respectively p<0.001). The majority of participants agreed they were motivated to implement behavioral changes, which was maintained at follow-up.

Conclusion: A pharmacy student-led interactive educational session improved knowledge and behavior change motivation among an undergraduate college community for the prevention of type 2 diabetes.

Poster 8

Title: Social Determinants of Health and Clinical Burden in Narcolepsy: A Retrospective Cohort Analysis

Authors: Anan Zhou, MPH1, Katarina Irwin, MS2, Sarah C. Markt, ScD, MPH3, Jon Michael Stroh2, Jiayuan Wang2, Martin Zagari, MD2, Caroleen Drachenberg, PhD, MSPH3, Silky Beaty, PharmD, MSPH3, Jessica K. Alexander, PhD3, Marisa Whalen, PharmD3, Junko Saber, MBA2 , Barbara Hutchinson, MD, PhD4

Institution: 1Genesis Research Group, Hoboken, NJ, USA; 2Innopiphany, LLC, Irvine, CA, USA; 3Jazz Pharmaceuticals, Palo Alto, CA, USA; 4Chesapeake Cardiac Care, Bowie, MD, USA

Objective: To describe demographic and clinical characteristics of individuals with narcolepsy, focusing on social determinants of health (SDoH) and health disparities.

Methods: A retrospective, observational study was conducted using electronic health records (EHR) and survey data from the All of Us Research Program. Individuals with narcolepsy were identified using SNOMED codes (1/1/2009–1/31/2022); index was defined as the earliest diagnosis date. Non-narcolepsy participants met inclusion criteria and were matched 3:1 to those with narcolepsy by age, sex, earliest EHR record, time in EHR, and SDoH survey completion. Descriptive statistics and multivariable logistic regression analyses summarized clinical comorbidities (from EHR) and survey data (including demographics and SDoH measures).

Results: Among 2766 participants (narcolepsy: n=694; non-narcolepsy: n=2072), mean age was 49 years and 70% were female. Most participants reported at least

some college education (narcolepsy: 80%; non-narcolepsy: 70%); however, a larger proportion of narcolepsy versus non-narcolepsy participants were out of work/ the workforce (39% vs 29%, respectively). Cost-related barriers to healthcare (75% vs 61%) and disability (51% vs 30%) were more frequently reported by narcolepsy versus non-narcolepsy participants. Among participants who completed the additional SDoH survey (narcolepsy: n=259; non-narcolepsy: n=768), food insecurity was more prevalent in narcolepsy participants (28% vs 16%). Narcolepsy participants reported higher levels of loneliness, every day and medical discrimination, and lower levels of social support and cohesion. Hypertension (38% vs 29%) and heart failure (7% vs 3%) prevalence at index was higher among narcolepsy versus non-narcolepsy participants. Participants with narcolepsy had higher odds (odds ratio [95% confidence interval]) of a cardiovascular (1.91 [1.54–2.36]), cardiometabolic (2.12 [1.73–2.59]), and cardiorenal (2.47 [1.72–3.56]) comorbidity versus non-narcolepsy participants.

Conclusion: Narcolepsy is associated with social and clinical challenges, including employment barriers, SDoH-related disparities, and higher comorbidity burden. Comprehensive and timely narcolepsy management strategies are warranted to address whole-person health.

DISCLOSURES

A Zhou is a full-time employee of Genesis Research Group and has received consulting fees from Jazz Pharmaceuticals, plc. K Irwin,

JM Stroh, J Wang, M Zagari, and J Saber are full-time employees of Innopiphany, LLC, which has received consulting fees from Jazz Pharmaceuticals, plc. SC Markt, C Drachenberg, S Beaty, JK Alexander, and M Whalen are full-time employees of Jazz Pharmaceuticals who, in the course of this employment, have received stock options exercisable for, and other stock awards of, ordinary shares of Jazz Pharmaceuticals, plc. B Hutchinson is a consultant to Jazz Pharmaceuticals, plc.

Poster 9

Title: Assessing Human Papillomavirus Knowledge and Vaccination Intentions Following a Virtual Educational Intervention for Parents and Guardians

Authors: Lalee Lo, Cristin Marchese, Julia Prajdic, Timika Robinson, Angela Saber, Destiny Self, PharmD Candidates

Institution: Wingate University School of Pharmacy

Objective: This study evaluates the impact of an educational intervention on HPV knowledge and vaccination intentions among parents and guardians of children aged 8–17.

Methods: Pharmacy students conducted virtual education sessions via Zoom for parents with children aged 8-17. The session covered HPV transmission, associated risks, and benefits of Gardasil-9. Participants completed pre- and post-session surveys assessing knowledge and willingness to vaccinate.

Results: A total of 50 participants attended the sessions, with 48

completing the pre-survey and 39 completing the post-survey. There was a significant increase in knowledge following the educational session (53% versus 90% correct, p<0.001). Willingness to vaccinate daughters increased from 68% very willing to 89% very willing, while willingness to vaccinate sons increased from 70% very willing to 91% very willing. Parents were 1.2 times more likely to choose “very willing” regarding vaccinating their children against HPV after receiving education.

Conclusions: Virtual educational interventions effectively enhance parental knowledge and positively influence HPV vaccination intent. Addressing vaccine hesitancy through structured educational programs may serve as a critical strategy to increase HPV immunization and reduce the burden of HPV-related malignancies.

Poster 10

Title: Naloxone Education for High School Faculty and Staff

Authors: Michelle Chaplin, PharmD, BCACP, CDCES; Christan Kelley, PharmD Candidate; Julianne Moore, PharmD Candidate; Alexis O’Kelley, PharmD Candidate; Josen Shepherd, PharmD Candidate

Objectives: The primary objective of this study was to evaluate changes in knowledge about naloxone and confidence in administering it before and after an educational intervention. Secondary objectives included assessing correlations between knowledge and age, and correlation between years of experience in the school system and knowledge.

Methods: This study evaluated the impact of a 30-minute educational intervention on high school faculty and staff’s knowledge of naloxone and confidence in administering it. A prospective cohort study was conducted in North Carolina high schools, using pre- and post-surveys to assess changes in knowledge and confidence.

Results: Fifty participants completed the study. The mean pre-survey knowledge score was 62.7% (SD = 0.14), increasing to 92.8% (SD = 0.07) post-intervention (p < 0.001). Confidence in naloxone administration significantly improved (p < 0.001). No significant correlations were found between baseline knowledge and age (r = 0.08) or years of experience in the school system (r = -0.16).

Conclusion: This study demonstrates that a brief educational session can significantly increase high school faculty and staff’s knowledge on opioid overdoses and confidence in administering naloxone during opioid overdose emergencies. The findings suggest that brief educational sessions effectively enhance knowledge and preparedness among school faculty and staff, reinforcing the need for naloxone training programs in high schools. Future research should explore long-term knowledge retention and the feasibility of integrating simulated overdose response training.

Poster 11

Title: Assessing University Employee Knowledge, Confidence, and Ability to Respond to an Opioid Overdose Following a Brief Educa-

tional Intervention

Authors: Lilianna S. Tulledge, PharmD Candidate 2026; Kati A. Smith, PharmD Candidate 2026; Camille N. Akins, PharmD Candidate 2026; Margaret Elizabeth Booth, PharmD Candidate 2026; Jacob E. Hunt, PharmD Candidate 2026; Melissa M. Dinkins, PharmD, BCACP

Institution: Wingate University School of Pharmacy, Wingate NC

Objective: To assess the impact of a brief educational intervention using the teach-back method on University employees’ knowledge, confidence, and ability to respond to an opioid overdose.

Methods: Education on opioid overdose response, including naloxone administration and the Good Samaritan Law, was provided by student pharmacists to University student employees, academic staff, administrative staff, support staff, and athletic staff. Changes in knowledge, confidence, and ability to respond to an overdose were evaluated using a pre- and post survey. Naloxone administration technique was evaluated using the teach-back method. A paired T-test was used to compare responses on pre- and post-surveys.

Results: Fifty-three employees participated in the intervention. Performance on all four knowledge-based questions significantly improved (p <0.001) following the intervention. Following the intervention, 100% of participants knew where to obtain naloxone (p < 0.001). Ten percent of participants identified as being confident or very confident in administering

naloxone before the intervention compared to 74% following the intervention (p <0.001). All participants demonstrated naloxone administration with two or fewer errors and 81% demonstrated zero errors following the intervention.

Conclusions: This innovative approach emphasized skill demonstration and legal protection while educating on response to opioid overdose. A brief educational encounter, requiring minimal resources, effectively enhances bystander knowledge and confidence in responding to an opioid overdose on a university campus.

Poster 12

Title: Risk Factors for Progression to Cirrhosis in Patients with Metabolic Dysfunction-Associated Steatohepatitis

Authors: Justin Boardwine, PharmD Candidate1,2; Katelyn Fishel, PharmD Candidate1,3; Deepti Narayanan, PharmD Candidate1,2; Logan Van Ravenswaay, PharmD4; Alexandra E. Mihm, PharmD, BCPS5,6; Sarah A. Nisly, PharmD, MEd, BCPS, FCCP1,4

Institutions: Atrium Health Wake Forest Baptist, Winston-Salem, NC1; University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC2; University of South Carolina College of Pharmacy, Columbia, SC3; Clinical Education Alliance, Reston, VA4; Butler University College of Pharmacy and Health Sciences, Indianapolis, IN5; Indiana University Health Methodist Hospital, Indianapolis, IN6

Objective: Current literature recognizes type 2 diabetes mellitus

and hypertension as cardiometabolic drivers of Metabolic Dysfunction-Associated Steatohepatitis (MASH) progression to advanced fibrosis and cirrhosis in long-term trajectories. However, comorbidities associated with cirrhosis development at diagnosis or during the first 12 months after diagnosis remains insufficiently studied. This study aims to evaluate which comorbidities are significantly correlated with the progression of MASH to cirrhosis at or within 12 months of diagnosis.

Methods: This IRB-approved, retrospective cohort study analyzed adult patients diagnosed with MASH within the Atrium Health Wake Forest Baptist system from January 1, 2018, to December 31, 2023. MASH diagnoses were identified using ICD-9/10 codes and confirmed through noninvasive or invasive testing. Patients with a prior diagnosis of MASH were excluded. The primary outcome was cirrhosis at time of diagnosis or within 12 months of diagnosis. Descriptive statistics were used to analyze baseline demographics. Spearman’s correlation coefficients were calculated using SPSS (v29) to assess associations between comorbidities and MASH progression to cirrhosis. Statistical significance was defined as p < 0.05.

Results: At or within 12 months of diagnosis, 35 out of 72 patients (48.6%) with MASH progressed to cirrhosis. Notably, diabetes mellitus (ρ = 0.419, p < 0.001) and hypertension (ρ = 0.404, p < 0.001) demonstrated moderate positive correlations with progression. Obesity, chronic kidney disease, and hyperlipidemia also trended toward positive correlations,

though none reached statistical significance.

Conclusions: This study found diabetes and hypertension were significantly associated with the early progression of MASH to cirrhosis. These findings suggest that cardiometabolic conditions play a substantial role in predicting fibrotic progression in MASH patients within a 12-month timeframe. Identifying these associations is important for early risk stratification and targeted management of patients with MASH. They also highlight the need for thorough risk assessment at diagnosis to guide prognosis and treatment planning.

Poster 13

Title: COVID-19 vaccinations administered in community-based pharmacies to children and adolescents in North Carolina.

Authors: Yeshaben Patel1,2, Carrie Blanchard3, Jenny Myers3, Anna Louise McNabb3, Yi-Fang (Ashley) Lee1, Amanda Savage1, Macary Marciniak1, Sachiko Ozawa1

Institutions: 1 Division of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill NC 2 Department of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill NC 3 Division of Public Health, Epidemiology Section, North Carolina Department of Health and Human Services, Raleigh NC

Objective: This study analyzed data to examine pharmacies’ role in the child and adolescent COVID-19

vaccination response, spanning from the initial vaccine rollout to the distribution of bivalent boosters.

Methods: We utilized COVID-19 vaccine management system (CVMS) operated by the North Carolina (NC) Department of Health and Human Services. Our sample population consisted of 1,747,790 children and adolescents aged 3-17 years between January 1, 2021, and June 26, 2023. We analyzed the data using descriptive statistics and logistic regression analyses to examine if demographic factors such as age, rurality, race, and ethnicity influenced child and adolescent COVID-19 vaccination uptake at both chain community pharmacies and independent pharmacies.

Results: Overall, COVID-19 vaccination rates were 59.1% among those aged 12-17 years, 37.4% among children aged 5-11 years and 3.5% of children aged 3-4 years. We discovered that pharmacies administered 42% of COVID-19 vaccinations among children and adolescents in North Carolina. Specifically, among vaccinated individuals, 18% of children aged 3-4 years, 37% of children aged 5-11 years, 47% of those aged 12-17 years, and received COVID-19 vaccination at a pharmacy in NC (p <0.001). Individuals were more likely to receive subsequent doses of vaccines at a community pharmacy (p < 0.001). There were no significant differences across children and adolescents

receiving COVID-19 vaccines from pharmacies across rural (42.0%), suburban (42.9%) and urban (42.2%) regions. Black and Hispanic children and adolescents were less likely to receive COVID-19 vaccines at pharmacies compared to other populations (p <0.001).

Conclusion: We found community pharmacies were utilized equally across rural, suburban and urban areas. Additionally, four in ten children and adolescents in NC visited community pharmacies to be vaccinated against COVID-19. This evidence demonstrates that pharmacies were a critical access point for child and adolescent vaccines across the state of NC.

NCAP Membership – Be Part of the Voice for Pharmacy in North Carolina

The North Carolina Association of Pharmacists (NCAP) is THE VOICE for pharmacy in our state. By joining, you not only support the profession but also gain access to exclusive resources, advocacy, and professional development opportunities.

Membership Benefits Include:

• Legislative & Regulatory Representation – NCAP advocates for you while you care for your patients.

• Professional Development & CE – Access live and on-demand continuing education, certificate programs, and discounted event registrations.

• Networking & Community – Connect through practice academies, new practitioner forums, and online networking groups.

• Practice Resources – Toolkits, grant opportunities, and innovative practice support.

• Career & Financial Tools – Job boards, student loan support, insurance discounts, financial services, and more.

• Exclusive Discounts – Savings on events, travel, entertainment, and subscriptions like Our State magazine.

When you join NCAP, you are strengthening the voice of pharmacy while advancing your own professional journey.

Explore full benefits and join today: https://ncap.memberclicks.net/membership-benefits

NCAP Has a New Address

After 10 years, NCAP has a new mailing address and will soon move into our new home. Our new mailing address is PO Box 58, Graham, NC 27253. Our new office is still being completed and we will let you know when we officially move into 36 Court Square SW, Graham, NC 27253. We will continue to operate as normal remotely until our move in date.

August Sunday Evening Webinar

Join us on August 24th for the August Sunday Evening Webinar. NCAP’s Executive Director, Dr. Penny Shelton, will share H67 - Profession Changing Legislation: What Does This Mean for You? What Are the Implications and Opportunities? This webinar will be ACPE accredited for 1 hour of live CE for pharmacists and pharmacy technicians. Learn more and register here!

Register for the 2025 Anti-Infective Conference Today!

Do you specialize in the treatment of infectious diseases, or just want to know more about what’s happening in this area of pharmacy practice? Then join us for the 2025 Anti-Infective Conference at Greensboro Country Club in Greensboro, NC on Friday, October 3rd. The conference is ACPE accredited for 5 hours of live CE. Learn more and register today!

Residency Showcase Registration is Open!

The 2025 Residency Showcase will be Saturday, November 8th at the Novant Forsyth Conference Center in Winston-Salem, NC. This is an awesome opportunity

for residency programs and 4th year students to meet in an effort to make that perfect match! Students and residency programs, visit our webpage to learn more and register to join us!

Ambulatory Care Huddle

Join NCAP’s virtual Ambulatory Care Huddle on the fourth Friday each month. These sessions create space for pharmacists to exchange ideas, discuss clinical pearls, and tackle real-world ambulatory care challenges together. For more information and to RSVP, click here.

Health-System and Hospital Huddle

Connect with peers in pharmacy leadership during NCAP’s Health-System & Hospital Huddle, held the third Friday each month. This forum spotlights operational, clinical, and financial issues unique to hospitals and health systems, with discussion driven by member-submitted topics. For more information and to RSVP, click here

Campbell University CE Event

Campbell University is hosting an event, Unraveling Interconnections: Metabolic Syndrome as the Driver of Cardio-renal-hepatic Disorders.This event is September 20th in Wrightsville Beach, NC. For all the details, visit Campbell’s events page.

Don’t miss an NCAP event! Check out our full calendar at ncpharmacists.org.