http://www.joline.de/sites/default/files/Folder_BonOs_Inject_0610_E_final

s

aap Implantate AG Lorenzweg 5 • 12099 Berlin Germany Fon +49 30 75019-0 Fax +49 30 75019-111 customer.service@aap.de www.aap.de

responsible manufacturer:

s

aap Biomaterials GmbH Lagerstraße 11-15 • 64807 Dieburg Germany Fon +49 6071 929-0 Fax +49 6071 929-100 biomaterials@aap.de www.aap.de

• Bone Cement for Spinal Applications

01-0310

®

1 x 24

(not for the USA)

ART.-NO.

WM 2007-02 / 0610

PACKAGING SIZE

BonOs Inject

BonOs Inject®

®

BonOs Inject

Bone Cement for Spinal Applications

Use of PMMA Cements for Spinal Surgery

Initially high viscosity for rapid application due to improved cohesion

PMMA has been used in orthopaedics for almost 50 years. During this time the fields of application have gradually

The chemical composition of the polymers ensures a high initial cohesion and therefore reduces the risk of cement leakage. After a

extended. Since the late '80s PMMA cement has also been used for spinal surgery – to stabilize the vertebra as

short waiting time the cement attains an ideal viscosity for application.

well as to relieve pain. BonOs® Inject was especially developed for these spinal applications.

BonOs® Inject fulfills all requirements of a bone cement for spinal surgery m m m m

Long application time Initially high viscosity for rapid application due to improved cohesion High radiopacity Good mechanical properties

Example of a cemented vertebra Chemical Composition

Powder (24 g)

Liquid (10 ml)

Poly (MMA)

Long application time The two components quickly mix up to a homogenous paste with the right viscosity for percutaneous injection. After a short

10.95 g

Poly (MA, MMA)

1.75 g

Zirconium dioxide

10.80 g

Benzoyl peroxide

0.50 g

MMA

9.93 ml

Dimethyl-p-toluidine

0.07 ml

Hydroquinone

60 ppm

waiting time BonOs® Inject can be injected for a long period of time in order to avoid time pressure during application.

Max. Time [min] at 19 °C

Temperature-Time Chart (e.g. 19 °C)*

19 ºC

0.5

Waiting

4.5

Application

14.0

Hardening

7.5

Application up to 14 mins.

Waiting up to 4.5 mins.

High radiopacity

Mixing

Hardening up to 7.5 mins.

The addition of a high amount of zirconium dioxide (ZrO²) allows an optimal X-ray visualization of BonOs® Inject for a safe use.

Zirconium dioxide has a positive influence on the mechanical stability and biocompatibility.

X-ray Images Cadaver Tests © PD Dr. K. Wilhelm, Bonn

Min.

5

10

15

20

* For further information see the Instructions for Use

25

Good mechanical properties The chemical composition of BonOs® Inject guarantees optimized mechanical properties which exceed the requirements of the ISO 5833 standard.

ISO 5833

Test conditions Application needle: ø 3 mm, length 120 mm Syringe capacity: 1 ml

Compression strength [MPa] E-modulus [MPa] Bending strength [MPa]

BonOs® Inject

≥70

122 ± 1,5

≥1800

4240 ± 177

≥50

70 ± 5,4