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The future is now

REDEFINING CONCEPTS IN IMPLANTODOLOGY

REDEFINING CONCEPTS IN IMPLANTODOLOGY

From the synergy between the exclusive macrogeometry and the most advanced surface nanoactivation emerges the Unitite®, an implant line that has revolutionized the world implantology market due to its originality, innovation and high performance.

From the synergy between the exclusive macrogeometry and the most advanced surface nanoactivation emerges the Unitite®, an implant line that has revolutionized the world implantology market due to its originality, innovation and high performance.

Exclusive HAnano surface:

Exclusive HAnano surface:

Developed in main universities in Sweden, this nanosurface significantly accelerates osseointegration.

Developed in main universities in Sweden, this nanosurface significantly accelerates osseointegration.

Healing Chambers:

Healing Chambers:

Only the external threads touches the bone tissue, while the internal threads are kept apart, promoting a very high quality hybrid healing.

Only the external threads touches the bone tissue, while the internal threads are kept apart, promoting a very high quality hybrid healing.

Accelerated Healing process:

Accelerated Healing process:

Increased hydrophilicity generated by a very thin layer of hydroxyapatite which enhances the activity of proteins involved in the osseointegration process.

Increased hydrophilicity generated by a very thin layer of hydroxyapatite which enhances the activity of proteins involved in the osseointegration process.

Distinctive Hybrid Macrogeometry:

Distinctive Hybrid Macrogeometry:

Accuracy of the drilling system and the design of the external threads give high stability, and minimize the compression of the healing bone tissue

Accuracy of the drilling system and the design of the external threads give high stability, and minimize the compression of the healing bone tissue

Scientific Evidence:

Scientific Evidence:

More than 10 years of research and development with the renowned scientists in at leading universities worldwide.

More than 10 years of research and development with the renowned scientists in at leading universities worldwide.

*See bibliographic reference

*See bibliographic reference

ONE CONCEPT, SEVERAL POSSIBILITIES

ONE CONCEPT, SEVERAL POSSIBILITIES

TWO IMPLANT LINES TO MEET THE MOST DIVERSE NEEDS

TWO IMPLANT LINES TO MEET THE MOST DIVERSE NEEDS

SLIM

Provides rehabilitation in narrow areas and limited interdental spaces, as well as upper lateral incisors and lower incisors areas.

Provides rehabilitation in narrow areas and limited interdental spaces, as well as upper lateral incisors and lower incisors areas.

INDICATIONS FOR CLINICAL USE:

INDICATIONS FOR CLINICAL USE:

2.9 – Lateral incisors (upper and lower) and Lower Centrals.

2.9 – Lateral incisors (upper and lower) and Lower Centrals.

COMPACT

COMPACT

Indicated for reduced bone availability in the upper and lower jaw.

Indicated for reduced bone availability in the upper and lower jaw.

INDICATIONS FOR CLINICAL USE:

4.0 – Upper and lower molars.

5.0 – Upper and lower molars.

6.0 – Upper and lower molars.

INDICATIONS FOR CLINICAL USE: – Upper and lower molars. 5.0 – Upper and lower molars. – Upper and lower molars.

UNITITE® SURGICAL KIT

UNITITE® SURGICAL KIT

UNITITE® SURGICAL KIT

UNITITE® SURGICAL KIT

A SINGLE KIT FOR THE ENTIRE UNITITE® LINE

A SINGLE KIT FOR THE ENTIRE UNITITE® LINE

A SINGLE KIT FOR THE ENTIRE UNITITE® LINE

A SINGLE KIT FOR THE ENTIRE UNITITE® LINE

To make your daily routine even more convenient and efficient, we have developed the Unitite single surgical kit for installing the full line:

Unique drills with DLC (Diamond Like Carbon):

› Less bone heating.

› Increased durability.

› High cutting power.

› Sharper angle.

Full closure: Keys don’t move regardless of position or movement.

Transmucous Meters:

Available for the complete line, assists in measuring and choosing prosthetic components.

Transmucous Meters: Available for the complete line, assists in measuring and choosing prosthetic components.

Reduced number of drills required for osteotomy.

Ease of clinical use through color-coding.

Ease of clinical use through color-coding.

Compact format makes it easier to sterilize in smaller autoclaves.

PRODUCT CODE: KCSU 05

PRODUCT CODE: KCSU 05

ORGANIZING BOX CODE: COSU 03

ORGANIZING BOX CODE: COSU 03

Inclined tray for easy viewing during surgery.

Accurate fits of

parts regardless of the position or movement.

To make your daily routine even more convenient and efficient, we have developed the Unitite single surgical kit for installing the full line: ONLY BEDONE WITH THE UNITITE® SURGICAL KIT.

implant insertion.

INSTALLATION OF THE UNITITE® IMPLANTS SHOULD ONLY BEDONE WITH THE UNITITE® SURGICAL

INSTALLATION OF THE UNITITE® IMPLANTS SHOULD ONLY BEDONE WITH THE UNITITE® SURGICAL KIT.

INSTALLATION OF THE UNITITE® IMPLANTS ONLY BEDONE WITH THE UNITITE

Torque Wrench: Bidigital key included for

UNITITE®

SAFE DRILL KIT

UNITITE® SAFE DRILL KIT

MAKING YOUR SURGERIES SIMPLER AND PRACTICAL

Stoppers available for each diameter of the drills.

All Unitite® drills are designed for use with the limiters in the Safe Drill kit. Less surgery time benefits professionals and patients. PRODUCT CODE: KUSD 02 ORGANIZING BOX CODE: COUSD 02

Greater safety of clinical use for cases with limited bone availability. Removable tray for

Hydroxyapatite the natural nanostructured stable coating osseointegration

Hydroxyapatite the natural bone nanostructured stable coating osseointegration

Hydroxyapatite (HA), which is the the natural bone structure, when nanostructured titanium implants, stable coating functioning as a scar osseointegration when compared to

From 2005 researchers

From 2005 on, Plus HAnano® surfaces researchers from leading universities

Scientists from several countries its effectiveness, the results of which dozens of articles in worldrenowned

of

From 2005 on, researchers from Scientists from its effectiveness, dozens of articles

Scientists from its effectiveness, dozens of articles

The Plus HAnano® coating is nanocrystals, with size and shape bone, sintered on a micro rough thick that promotes a change in surface hydrophilicity and providing a substrate osteoblasts multiplication.

The Plus HAnano® nanocrystals, with bone, sintered thick that promotes hydrophilicity and osteoblasts multiplication.

The Plus HAnano® nanocrystals, bone, sintered thick that promotes hydrophilicity osteoblasts

Scanning Electron
Scanning Electron Microscopy demonstrating
Scanning Electron

Removable tray for easy cleaning.

Stoppers available for each diameter of the drills.

Hydroxyapatite (HA), which is the main mineral present in the natural bone structure, when applied on the surface of nanostructured titanium implants, forms a homogeneous and stable coating functioning as a scar catalyst that speeds up osseointegration when compared to conventional surfaces.

Hydroxyapatite (HA), which is the main mineral present in the natural bone structure, when applied on the surface of nanostructured titanium implants, forms a homogeneous and stable coating functioning as a scar catalyst that speeds up osseointegration when compared to conventional surfaces.

From 2005 on, Plus HAnano® surfaces have been developed by researchers from leading universities in Gothenburg (Sweden). Scientists from several countries have tested and approved its effectiveness, the results of which have been published in dozens of articles in worldrenowned scientific journals.

From 2005 on, Plus HAnano® surfaces have been developed by researchers from leading universities in Gothenburg (Sweden). Scientists from several countries have tested and approved its effectiveness, the results of which have been published in dozens of articles in worldrenowned scientific journals.

The Plus HAnano® coating is formed by hydroxyapatite nanocrystals, with size and shape similar to those of human bone, sintered on a micro rough titanium measuring 20 nm thick that promotes a change in surface energy, increasing the hydrophilicity and providing a substrate that stimulates a greater

The Plus HAnano® present on the surface of the S.I.N. implants has shown an improvement in scar response in molecular tests of signal transduction, where the proteins involved in the scarring process recorded a substantial increase in concentration, presenting the coating positive effect on the interaction with the pre-osteoblastic cells.

The Plus HAnano® present on the surface of the S.I.N. implants has shown an improvement in scar response in molecular tests of signal transduction, where the proteins involved in the scarring process recorded a substantial increase in concentration, presenting the coating positive effect on the interaction with the pre-osteoblastic cells.

Hydroxyapatite (HA), which is the main mineral present the natural bone structure, when applied on the surface nanostructured titanium implants, forms a homogeneous stable coating functioning as a scar catalyst that speeds osseointegration when compared to conventional surfaces.

Hydroxyapatite (HA), which is the main mineral present the natural bone structure, when applied on the surface nanostructured titanium implants, forms a homogeneous stable coating functioning as a scar catalyst that speeds osseointegration when compared to conventional surfaces.

Likewise, there was an increase in the concentration of important osteogenic markers, such as alkaline phosphatase and osteocalcin, in clear signalling of the mineralization process acceleration.

All Unitite® drills are designed for use with the limiters in the Safe Drill kit.

The Plus HAnano® coating is formed by hydroxyapatite nanocrystals, with size and shape similar to those of human bone, sintered on a micro rough titanium measuring 20 nm thick that promotes a change in surface energy, increasing the hydrophilicity and providing a substrate that stimulates a greater

All Unitite® drills are designed for use with the limiters in the Safe Drill kit.

Likewise, there was an increase in the concentration of important osteogenic markers, such as alkaline phosphatase and osteocalcin, in clear signalling of the mineralization process acceleration.

From 2005 on, Plus HAnano® surfaces have been developed researchers from leading universities in Gothenburg (Sweden). Scientists from several countries have tested and approved its effectiveness, the results of which have been published dozens of articles in worldrenowned scientific journals.

From 2005 on, Plus HAnano® surfaces have been developed researchers from leading universities in Gothenburg (Sweden). Scientists from several countries have tested and approved its effectiveness, the results of which have been published dozens of articles in worldrenowned scientific journals.

Among the most relevant aspects, with the greatest clinical significance, is the bone mechanical quality which is formed around this highly hydrophilic Plus surface, which derives from the resulting ionic potential of the Plus HAnano®.

Among the most relevant aspects, with the greatest clinical significance, is the bone mechanical quality which is formed around this highly hydrophilic Plus surface, which derives from the resulting ionic potential of the Plus HAnano®.

The Plus HAnano® coating is formed by hydroxyapatite nanocrystals, with size and shape similar to those of human bone, sintered on a micro rough titanium measuring 20 thick that promotes a change in surface energy, increasing hydrophilicity and providing a substrate that stimulates a greater osteoblasts multiplication.

The Plus HAnano® coating is formed by hydroxyapatite nanocrystals, with size and shape similar to those of bone, sintered on a micro rough titanium measuring thick that promotes a change in surface energy, increasing hydrophilicity and providing a substrate that stimulates a osteoblasts multiplication.

Greater safety of clinical use for cases with limited bone availability.

Greater safety of clinical use for cases with limited bone availability.

Scanning Electron Microscopy demonstrating osteoblastic cell on HAnano surface. Courtesy: Cavalcanti JH, Tanaka M, Bezerra FJ, CBPF RJ.
Scanning Electron Microscopy demonstrating osteoblastic cell on HAnano

RESULTS OF CLINICAL EVIDENCE

EVIDENCE STUDIES

IN VITROS TESTS, IN VIVO TESTS AND CLINICAL STUDIES

RESULTS OF CLINICAL EVIDENCE

IN VITROS TESTS, IN VIVO TESTS AND CLINICAL STUDIES

SUCCESSFULLY TESTED:

50+ clinical consultants and researchers

94% do volume ósseo vestibular encontrado nas avaliações.

SUCCESSFULLY TESTED:

50+ clinical consultants and researchers

94% do volume ósseo vestibular encontrado nas avaliações.

Source: Clinical Oral Implants Research

Oral and lingual bone level changes after immediate implantation of four implant surfaces: a study in dogs.

Source: Clinical Oral Implants Research

Bonfante A., Estevam

Oral and lingual bone level changes after immediate implantation of four implant surfaces: a study in dogs.

Bonfante A., Estevam

universities worldwide, to major international

tested Unitite® prior to launch, installing over 2.000 implants

tested Unitite® prior to launch, installing over 2.000 implants

universities worldwide, to major international

High success rate recorded a 0.68% loss compared to its sale in its first year.

High success rate recorded a 0.68% loss compared to its sale in its first year.

SUCCESSFULLY TESTED: 94% do volume ósseo vestibular encontrado nas avaliações.

SUCCESSFULLY TESTED: 94% do volume ósseo vestibular encontrado nas avaliações.

Source: Clinical Oral Implants Research Oral and lingual bone level changes after immediate implantation of four implant surfaces: a study in dogs. Bonfante A., Estevam

Source: Clinical Oral Implants Research Oral and lingual bone level changes after immediate implantation of four implant surfaces: a study in dogs. Bonfante A., Estevam

In short- and long-term clinical evaluations at leading universities worldwide, Unitite® had the lowest marginal bone loss compared to major international premium implants.

In short- and long-term clinical evaluations at leading universities worldwide, Unitite® had the lowest marginal bone loss compared to major international premium implants.

SCIENTIFIC PUBLICATIONS

SCIENTIFIC PUBLICATIONS

evaluated and proven by numerous scientific institutions worldwide. Check out some of them

The positive and superior results of HAnano ® have been evaluated and proven by numerous scientific studies in several recognized universities and research institutions worldwide. Check out some of them in the QR Codes below.

evaluated and proven by numerous scientific institutions worldwide. Check out some of them

The positive and superior results of HAnano ® have been evaluated and proven by numerous scientific studies in several recognized universities and research institutions worldwide. Check out some of them in the QR Codes below.

INFLUENCE EARLY BONE FORMATION.

formation.

formation.

NANO HYDROXYAPATITE STRUCTURES INFLUENCE EARLY BONE FORMATION.

INFLUENCE EARLY BONE FORMATION.

Nano hydroxyapatite structures influence early bone formation.

NANO HYDROXYAPATITE STRUCTURES INFLUENCE EARLY BONE FORMATION.

Albrektsson T, Wennerberg A. 87A, Issue 2,2008, pp. 299-307.

Meirelles L, Arvidsson A, Andersson M, Kjellin P, Albrektsson T, Wennerberg A.

Nano hydroxyapatite structures influence early bone formation.

Journal of Biomedical Materials Research Part A Volume 87A, Issue 2,2008, pp. 299-307.

Albrektsson T, Wennerberg A. Volume 87A, Issue 2,2008, pp. 299-307.

Meirelles L, Arvidsson A, Andersson M, Kjellin P, Albrektsson T, Wennerberg A. Journal of Biomedical Materials Research Part A Volume 87A, Issue 2,2008, pp. 299-307.

NANOTOPOGRAPHICAL MODIFICATIONS ON THE EARLY

THE EFFECT OF CHEMICAL AND NANOTOPOGRAPHICAL MODIFICATIONS ON THE EARLY STAGES OF OSSEOINTEGRATION.

NANOTOPOGRAPHICAL MODIFICATIONS ON THE EARLY

Wennerberg A.

modifications on the early stages of osseointegration.

The effect of chemical and nanotopographical modifications on the early stages of osseointegration.

THE EFFECT OF CHEMICAL AND NANOTOPOGRAPHICAL MODIFICATIONS ON THE EARLY STAGES OF OSSEOINTEGRATION.

Meirelles L, Currie F, Jacobsson M, Albrektsson T, Wennerberg A.

modifications on the early stages of osseointegration.

The effect of chemical and nanotopographical modifications on the early stages of osseointegration.

Implants Volume 23, Issue 4, 2008, pp. 641-647.

Wennerberg A. Implants Volume 23, Issue 4, 2008, pp. 641-647.

The International Journal of Oral and Maxillofacial Implants Volume 23, Issue 4, 2008, pp. 641-647.

Meirelles L, Currie F, Jacobsson M, Albrektsson T, Wennerberg A.

The International Journal of Oral and Maxillofacial Implants Volume 23, Issue 4, 2008, pp. 641-647.

IMPROVE BONE NANOMECHANICAL PROPERTIES.

NANO HYDROXYAPATITE-COATED IMPLANTS IMPROVE BONE NANOMECHANICAL PROPERTIES.

nanomechanical properties.

IMPROVE BONE NANOMECHANICAL PROPERTIES.

Nano hydroxyapatite-coated implants improve bone nanomechanical properties.

NANO HYDROXYAPATITE-COATED IMPLANTS IMPROVE BONE NANOMECHANICAL PROPERTIES.

N, Currie F, Hayashi M, Janal MN, Andersson M,

nanomechanical properties.

Jimbo R, Coelho PG, Bryington M, Baldassarri M, Tovar N, Currie F, Hayashi M, Janal MN, Andersson M, Ono D, Vandeweghe S, Wennerberg.

Nano hydroxyapatite-coated implants improve bone nanomechanical properties.

Tovar N, Currie F, Hayashi M, Janal MN, Andersson M,

A.J Dent Res. 2012;91(12):1172-7.

Jimbo R, Coelho PG, Bryington M, Baldassarri M, Tovar N, Currie F, Hayashi M, Janal MN, Andersson M, Ono D, Vandeweghe S, Wennerberg.

A.J Dent Res. 2012;91(12):1172-7.

SCIENTIFIC PUBLICATIONS

Shunmugasamy VC, et al. Influence of clinically relevant factors on the immediate biomechanical surrounding for a series of dental implant designs. Journal of Biomechanical Engineering 2011; 133: 031005-1 - 031005-9

Meirelles L, et al: Nano hydroxyapatite structures influence early bone formation. J Biomed Mater Res A. 2008 Nov;87(2):299-307

Pessoa RS, Et al. Avaliação da estabilidade dos tecidos duros e moles em implantes imediatos com carga imediata em área estética: estudo clínico. Dental Press Implantol. 2015 Apr-Jun;9(2):100-9

Bezerra FJB, Pessoa RS, Zambuzzi WF. Carregamento funcional imediato ou precoce de implantes com câmara de cicatrização e nano-superfície: estudo clínico prospectivo longitudinal. Innov Implant J, Biomater Esthet 2014; 9 (2/3): 13-17

Coelho PG, Marin C, Granato R, Bonfante EA,Lima CP, Oliveira S, Ehrenfest DMD, SuzukiM. Alveolar Buccal Bone Maintenance AfterImmediate Implantation with a Surgical FlapApproach: A Study in Dogs. The InternationalJournal of Periodontics & Restorative Dentistry2011;31:e80–e86

Coelho PG, Granjeiro JM, Romanos GE, SuzukiM, Silva NR, Cardaropoli G, et al. Basic researchmethods and current trends of dental implantsurfaces. J Biomed Mater Res B Appl Biomater2009;88(2):579-96.

Jimbo R, Coelho PG, Bryington M, BaldassarriM, Tovar N, Currie F, et al. Nano hydroxyapatitecoatedimplants improve bone nanomechanicalproperties. J Dent Res 2012;91(12):1172-7.

Arvidsson A, Franke-Stenport V, Andersson M,Kjellin P, Sul YT, Wennerberg A. Formation ofcalcium phosphates on titanium implants with fourdifferent bioactive surface preparations. An in vitrostudy. J Mater Sci: Mater Med 2007; 18:1945-1954

Barkarmo S, Wennerberg A, Hoffman M,Kjellin P, Breding K, Handa P, Stenport V. 2013.

Nanohydroxyapatite-coated PEEK implants: Apilot study in rabbit bone. J Biomed Mater Res A 2013; 101A:465–471.

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