PHARMACOVIGILANCE INTERVIEW QUESTIONS AND ANSWERS FOR FRESHERS IN 2019

PHARMACOVIGILANCE INTERVIEW QUESTIONS AND ANSWERS FOR FRESHERS IN 2019 Let us see the list of pharmacovigilance interview questions and answers for freshers. This blog is very useful for the candidates who want to make their career in clinical research. Let us see this list of pharmacovigilance interview questions and answers for TCS, Cognizant and Accenture.

In this blog consists of detailed information regarding : Pharmacovigilance Interview Questions and Answers for Freshers in TCS Pharmacovigilance Interview Questions and Answers for Freshers in Accenture Pharmacovigilance Interview Questions and Answers for Freshers in Cognizant A) Pharmacovigilance interview questions and answers for freshers in TCS : 1) Define aggregate reporting It is a procedure that fetches all the cumulative safety data of a medicinal product on a daily basis from various sources. Such data is submitted to regulatory authorities. Unless and until the company medicinal product has been present in the world. That particular medicinal product’s aggregate safety product must be submitted to regulatory authorities.

2) Define signal and its types The causal relationship is the basis for the signal which is a reported information. This information is very difficult to understand or not well reported before. For generating a signal 2 or more than 2 reports are needed.

There are three types of signals: 1. Confirmed signals 2. False signals 3. Unconfirmed signal: need further information.

3) Define causality and mention causality assessing methods There are a various set of factors mainly for drug and adverse event which are related is termed as causality. e.g: European ABO system, WHO assessment scale, , Kramer scale etc.

4)Sources of Adverse Event Reports?

The following sources exhibit the adverse effects: Solicited reports from Clinical trials Continuous reporting by healthcare professionals

Patient support programs, marketing surveys, patient registries, disease management, and medical chart reviews are provided by stimulated reports.

Healthcare professionals report continuously 5) What do you mean by life-threatening diseases? and explain it?

Death causing diseases which are chronic and does not have a proper cure or treatment like Hypertension, Diabetes, HIV, Neurological conditions, Cancer etc.

B) Accenture pharmacovigilance interview questions and answers for freshers: 1) Explain about Interventional studies and Noninterventional studies?

Interventional study: In the clinical study, the treatment or intervention is assigned. One more group will not fetch the treatment. All such details will be provided in the study protocol in advance and it checks the medicinal product effect on the health-related outcome.

Non-interventional study: In a normal way, the participants receive a medicinal product. Such studies assist to find various aspects of medicinal product use. Any extra diagnostic methods are not used to measure efficacy.

2) Tell us something about diabetes and mention the drugs used for its treatment?

This is a metabolic disorder and it is of two types: Type 1 diabetes: Here insulin is not produced from the pancreas. There are several reasons for the damage of insulin produced cells.

Type 2 diabetes: Here the patients are not able to use the insulin properly in the body. This is the most common diabetes. Gliclazide, Metformin, Simvastatin, Glimperimide etc.

Gestational diabetes: This happens during pregnancy.

This is disorder occur in pregnancy.

3) Explain about Hypertension?

Normal blood pressure is 120/80. 120 means systolic blood pressure and 80 diastolic blood pressure. High blood pressure is a long-term medical problem. Hypertension means the pressure on the blood is high enough. Excess salt, smoking, excess body weight, and alcohol leads to blood pressure.

4) Full form of ECG, COPD disease, EEG, OGTT test, HIV, ICU, and NIDDM? ECG- Electrocardiogram COPD- Chronic Obstructive Pulmonary Disease EEG- Electroencephalogram OGTT- Oral Glucose Tolerance Test

HIV- Human Immunovirus ICU- Intensive Care Unit NIDDM- Non-Insulin Dependent Diabetes Mellitus.

5) What are the various parenteral routes of administration?

Intravenous (IV) route – Drug injected directly into a vein.

Intramuscular (IM) route- Drug injected into the muscle.

Subcutaneous (SC) route- Drug given via the subcutaneous layer present below the dermis and epidermis layer of the skin.

Intraarterial (IA) route- Drug injected via the artery which specific for a particular organ.

Intraarticular route: Drug injected in joint space by preventing the systemic circulation.

Intrathecal route: Drug injected into the spinal canal or subarachnoid space.

Intradermal route: Medicine injected via the skin dermis layer.

6) Explain the functions of the Liver, lungs, and kidney?

Liver: In a protein, fat, and carbohydrates metabolism, a significant role is played by this body part.

The blood chemicals are detoxified by it. The minerals, glycogen, and vitamins are stored in it. The bile salts are produced in the liver and they help in breaking down the fats in the small intestine.

Lungs: Exchanging the gases at the time of respiration is the main function of the lungs. It offers oxygen to the blood (RBC) and removes carbon dioxide from the blood(RBC).

Kidneys: The water fluids are balanced well and it continuously filters the blood and retains the minerals by excreting the toxic substances from the body.

C) Pharmacovigilance interview questions for freshers in Cognizant What is Pharmacovigilance?

List down the least criteria required for a valid case?

Define Adverse Drug Event (ADE)?

Define an Adverse Drug Reaction (ADR)?

Elaborate the difference between an ADE and ADR? Explain causality?

CRB Tech is one of the best Clinical Research training institutes in Pune which offers jobs in Top Pharmacovigilance Companies.