UltraPulse Alpha

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DO YOU HAVE WHAT IT TAKES TO BE ABOVE A ?

MARKET PENDULUM SWINGS,

BUT ULTRAPULSE IS ALWAYS HERE

Expanding solutions based on ULTRApulse CO2 technology

1990’s Full-field ablative laser Aggressive treatments Amazing results

2005

First ablative fractional laser – UltraPulse® CPG Results like never before, with half the downtime

2012

Deep fractional with SCAARFX ™ Opening the ability to treat scars and thick lesions

2017

Surge in full-field ablative procedures

2023

ULTRApulse Alpha sets a new bar in aesthetic treatments

Revolving door of other technologies

2002

Non-invasive RF skin tightening

2004

Non-ablative fractional lasers

2008-2015

IPL golden era

2011-2015

Cryolipolysis hype

2015

HIFU (High-Intenstiy Focused Ultrasound)

2016-2018

Picosecond lasers

2019-2021 RFMN wave

LUMENIS’ HERITAGE - BACKING YOU UP!

ULTRApulse Alpha succeeds decades-long heritage, lead by the experts who introduced CO2 lasers to aesthetics. Thousands of devices were sold all over the world thus far, treating millions of patients to date, changing lives on a day-to-day basis. We welcome you to join the success today, and offer better, more accurate and long-lasting care for your patients

1964

CO2 laser invention

1990 Introduction of ULTRApulse® technology (UltraPulse 5000C)

1988

1998 ULTRApulse® Encore™

2005

1973

World’s first CO2 surgical laser

Rox Anderson sets the golden rule for CO2 photothermolysis

2004 Manstein et al. coin the concept f Fractional Photothermolysis

Lumenis launches ActiveFX™, the first fractional ablative modality using CO2 with CPG

2007

Lumenis launches DeepFX™, the first micro fractional CO2

2012

Lumenis launches SCAAR FX™, the deepest micro fractional CO2 in a single pulse

2023

Lumenis launches the ULTRApulse Alpha - the next generation of fractional ablative CO2 lasers

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WHY SHOULD THIS EXCITE YOU?

WOW Results In Just One Treatment

The non-surgical procedure that pays the most per session

Enhanced performance: power, speed, scan modes

CO2 made simple with presets and automations

CO2 2023: Superior Technology Made Simple For All

WIZ technology for remote and rapid service, and preventive maintenance

Lumenis’ heritage – long-time innovator and first to market with fractional CO 2 ablative laser

New GUI and system features for faster, safer and easier treatments

Long term investment in the future of CO 2 lasers and trade-in plans

QR codes for recommended best practices per treatment type

Expand your business!

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THE ALPHA OF SKIN CARE

The best laser technology in aesthetics has been perfected, and made easier to use safely, more powerful, faster and offers possibilities like never before.

ULTRApulse Alpha conveys the well anticipated combination of technological advancement and ease of use, allowing you to achieve WOW results in just one treatment.

With an unmatched peak power of 240Watts (!), and shortest pulse duration, the ULTRApulse Alpha produces more ablation, with less heat and residual damage - and that means achieving remarkable results while maintaining patient comfort and shorter downtime.

The Alpha Air Brush quick treatment mode, available ONLY with the ULTRApulse Alpha, and enhanced by the CoolScan™ and BrushFX™ scanning options, is a game changer for anyone wanting to perform ablative treatments.

Developed alongside laser-savvy professionals, the Alpha provides treatment-based recommendations and presets, giving you full control and confidence every pulse of the way.

Lumenis’ engineers have further enhanced the ease of use of this advanced technology with built-in smoke evacuator control and additional features allowing you to focus your attention on your patient, because that’s what really matters!

WOW RESULTS IN JUST ONE TREATMENT

Aesthetic and functional life-changing results

WRINKLES AND FACIAL RESURFACING

Before After

Before After

PERIORBITAL RESURFACING & DYSCHROMIA

Before After

Before After

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Courtesy of Ofir Artzi, MD Courtesy of David Kaufman, MD Courtesy of Clayton Moliver, MD Courtesy of Kevin Duplechain, MD

REVISE SCARS YOU THOUGHT WOULD REMAIN FOREVER

Before After Before After

BLEPHAROPLASTY & RHINOPHYMA

Before After Before After

Courtesy of Peter Peng, MD Courtesy of Jill S.Waibel, MD Courtesy of Girish Munavalli, MD
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Courtesy of Alina Fratila, MD

75 x $2,775 = $208,125 In One Month

A MONTH IN THE LIFE OF AN AVID ALPHA USER | 8
Total number of patients 2 1 5 3 1 1 2 2 4 2 3 1 6 5 4 7 6 6 0 10 20 30 40 50 60 70 80 7 2 5 Number of daily patients - first 31 days Patients Per Day Total #Patients
*According to realself.com Monthly Treatments Average Treatment Cost* Monthly Pay ~ROI in Months 10 $2,775 $27,750 10 15 $41,625 6.5 20 $55,500 5 25 $69,375 4
ROI EXAMPLE WITH ULTRAPULSE ALPHA

Immediately upon testing the new ULTRApulse Alpha, I loved it. It’s designed for the provider and patient’s benefit. The new features work together to create advanced usability that facilitates treatment...

Inferior devices are not a bargain. They’re the opposite because they put you and your patients at an unacceptable disadvantage. So do your homework, make the right choice, and learn your new technology. Once you have the physics down and you’re giving your patients extraordinary outcomes, you’ll be glad you did.

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NEW TO CO2? HERE IS HOW IT WORKS

Wavelengths below 2,000nm do NOT provide ablation, but only heat

Er:YAG (2,940nm) is too ablative. The skin becomes a barrier and there is not enough penetration (therefore, less collagen production stimulation). Lack of dermal heating leads to bleeding without the ability to coagulate.

CO2 (10,600nm) provides an ideal combination of ablation AND heat to the dermis

DeepFX/SCAARFX mode: Energy 100mJ Penetration depth 3.3mm Energy 150mJ Penetration depth 4mm Non-ablative (e.g. 1565 nm) Er:YAG (2940nm) (Deep) CO2 (10,600 nm)
ULTRApulse Alpha
| 10 Laser Absorption and Tissue Penetration 105 104 103 102 101 100 10-1 10-2 10-3 10-4 .1 Absorption Coeffcient (1/cm) 1 10 Er:YAG 2940nm Infrared 1064-1600nm CO2 10,600nm Wavelength (Micrometers)

Fractional vs. Non-Fractional Resurfacing:

• Full-field resurfacing affects the entire area of treated skin

• Fractional resurfacing treats a portion of the scanned area, leaving untouched areas of skin

• Untouched areas of skin allow faster recovery, reduced patient discomfort, less downtime and faster healing

• ULTRApulse Alpha offers a variety of scan densities, allowing provider maximal control

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Deep Fractional
Superficial
Density |
Density | Shape 1 1% 3 5% 5 10% 9 25%
CPG (1-9)
Shape DeepFX (1-25)
*Ilustration. Additional densities are available for maximal control.

WHAT IS REQUIRED OF A CO2 LASER?

The thermal relaxation time (TRT) of tissue is about 0.8 ms.. We must deliver the CO2 laser necessary 5 J/cm2 in at most, a 0.8 ms pulse, preferably less, if we expect to minimize excess injury to the underlying tissue.

ULTRApulse Alpha’s high-peak power drives shorter pulses to penetrate deeper, with minimal collateral damage. This reduces patient discomfort and downtime

| 12 CW | Long pulse UP | Short pulse
R. Rox Anderson, MD

NOT ALL CO2 LASERS ARE CREATED EQUAL

Only with pulse stacking

Caution

Lower power lasers allow heat dissipation and extended collateral thermal damage that takes longer to heal

The Power Advantage of ULTRApulse

Deepest penetration, with less energy needed to reach the same ablation depth

Less residual heat

Less risks and side effects

Better wound healing

Ablation rate faster than thermal relaxation time

Others even require pulse stacking or use of additional technologies

Power

1 week post with ULTRApulse Alpha technology

1 week post with other low power CO2 laser

4000 3500 3000 2500 2000 1500 1000 500 0 160 140 120 100 80 60 40 20 Ablation depth in µm Energy per pulse in mJ 0 600 ULTRApulse Competitor1 Competitor2 Competitor3
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Low Power Laser ULTRApulse

WHAT’S NEW IN ULTRAPULSE ALPHA – THE SHORTLIST

Enhanced power and speed like never before, enabling safer and faster treatments

Alpha Air Brush - Take your resurfacing skills to the next level

• The unique CPG scanner supports a wide range of modalities, provides powerful pulses over a large spot size, with a short time-off between pulses

• With a collimated beam for full accuracy from almost any distance from the skin, the CPG allows you to use a “painting” method to cover a large area faster than ever before

• Alpha Air Brush shortens treatment duration without compromising efficiency, enabling you to perform a full facial resurfacing in less than 15 minutes, while providing your patient with the results they desire

New proprietary scanning modalities

CoolScan™ - non-sequential scan pattern, reducing pain, patient discomfort and downtime, with either CPG or DeepFX

BrushFX™ - offering inhomogeneous scan pattern, further reducing potential treatment demarcations

Presets and automations tailored by professionals straight into the GUI - assisting you in getting better results, while maintaining a safe treatment

QR codes referring to best practice clinical recommendations, helping you every pulse of the way

Usability features making your life easier - smoke evacuator and purge air pump control from the device, easy aiming beam adjustment, counterbalanced articulated arm, and more!

QR Codes Per Indication For Clinical Best Practices

Try me!

CLINICALLY VALIDATED TECHNOLOGY IN DOZENS OF PEER REVIEWED PUBLICATIONS

ULTRApulse Alpha technology is supported by many peer reviewed articles, portraying its efficiency in treating a variety of indications

Himza, et al., 2021 | "This systematic review suggests ablative laser use for skin resurfacing is a safe and effective modality to treat a range of pathologies... these results suggest that ablative lasers are a superior, safe, and effective modality to treat damaged skin".

Seago, et al., 2020 | "Lasers are a first-line therapy in the management of traumatic scars and contractures, and patients without access to these treatments may not be receiving the best available care after injury".

Miletta, et al., 2019 | "Fractional ablative laser treatment provides significant, sustained improvement of elasticity, thickness, appearance, and symptoms of mature hypertrophic burn scars".

And dozens more in the ULTRApulse Alpha Clinical Compendium

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JOIN THE SUCCESS OF ALPHA EARLY ADOPTERS

After comparing all fractional-ablative devices, it turns out that the short pulse delivered by ULTRApulse Alpha creates a deep-clean wound, while other devices are less powerful and might deliver more complications.

Lumenis does such a great job, and the new ULTRApulse Alpha is an amazing device that has upped the game with many new features.

The original UltraPulse platform was so effective, but the Alpha seriously ups the aesthetic laser game. There’s a lot of innovative science that went into this device. It takes you into a ‘Star Wars’ kind of technology, in which you achieve better patient results with far less pain.

While the platform maximizes safety in so many ways, it is also powerful. It consistently fires in a way that is safe for the skin.

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J. Kevin Duplechain, MD Jill S. Waibel, MD | FL, USA Dermatologist Medical Director and Owner, Miami Dermatology and Laser Institute, Miami, FL J. Kevin Duplechain, MD | LA, USA Cosmetic Surgeon President of The Aesthetic Medicine Center, Lafayette, LA 2022-2023 President of the American Academy for Cosmetic Surgery (AACS)

Ofir Artzi, MD | Tel-Aviv, Israel

Dermatologist

Head of Aesthetic Dermatology, TLV Medical Center

Thomas Beachkofsky, MD | FL, USA

Dermatologist

James A. Haley VA, Florida

Suzanne L. Kilmer, MD | CA, USA

Dermatologist

Founder of the Laser and SkinSurgery Center of Northern California

This CAN be you...

UltraScan™

CPG 1.3mm

Full\Fractionated Superficial Resurfacing

TrueSpot™

Collimated 2mm

Multi-pass debulking, commonly used in Rhinophyma

Microscanner

0.12mm

Deep Fractional

Penetrating up to 4mm in a single pulse

Incisional HP

0.2 & 1.0mm

Focused beam for incision/ excision, blepharoplasty, acne scars and more

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ONE DEVICE | FIVE APPLICATORS | ONE SUCCESS STORY

SPECIFICATIONS

TECHNICAL SPECIFICATIONS

Spot Size

Scan Size

Density per Scan

Full Resurfacing, fractional, incisional and excisional capabilities

Aiming Beam

Beam Delivery

Cooling

Warranty and Coverage

Electrical

0.12 mm DeepFX™ Microscanner; 1.3mm UltraScan™ CPG Scanner; 2.0 mm TrueSpot™ Handpiece; 0.2-1 mm Incisional Handpiece

Hex. 16 mm

Fractional: 1-100%, full ablative: >100%

Yes

≤5mW red diode laser, 635 nm, adjustable intensity

Articulated arm w/240 cm (94.5 in) reach, 360° rotation

Self-contained, closed cycle

1 Year standard

100 – 240 VAC; 16 A max.; 50/60 Hz, Single Phase

Weight 135 kg (297 lbs)

Dimensions (WxDxH) 44 cm x 65 cm x 100-195 cm (17.3 x 25.6 x 40-77 in)

WARNINGS AND RISKS

CO2 lasers are intended solely for use by professionals trained in the use of the Carbon Dioxide laser (10.6 μm) wavelength. Incorrect treatment settings or misuse of the technology can present risk of serious injury to patient and operating personnel. Risks that may be associated with any CO2 laser procedure may include change of pigmentation, infection, erythema, skin induration or scarring.

Read and understand the CO2 systems and accessories operator manuals for a complete list of intended use, contraindications, and risks.

The use of Lumenis® CO2 laser is contraindicated where a patient has taken Accutane (Isotretinoin) within the past 6-12 months, has a history of keloid formation and demonstrate excessive or unusually prolonged erythema.

MANUFACTURED

LUMENIS

Dreieich-Dreieichenhain,

© 2023 All Rights Reserved. The Lumenis Be Group of Companies. Lumenis, its logo, UltraPulse, ActiveFX, DeepFX, BrushFX, TotalFX and SCAARFX are trademarks or registered trademarks of the Lumenis Be Group of Companies. Specifications are subject to change without notice.

Type UP and CW Power to Tissue 60 W Peak Power  240 W
Wavelength 10,600 nm Laser
Industrial
Street 9, P.O.B. # 426
FOR LUMENIS BE LTD. Yokneam
Park Hakidma
Yokneam 2069236, Israel Tel: +972.77.959.9000
(GERMANY) GMBH Heinrich-Hertz-Str 3 D-63303
Germany
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+ 91 124 422 07 95 KOWLOON, HONG KONG T + 852 217 428 00 F + 852 272 251 51 For more information: www.lumenis.com Rx ONLY 0483
ASIA
T
PB-00058610 Rev A

SIMP Y WOW.

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