July12 19

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JULY 12, 2019

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CBD The ABCs of

PART III

CBD: WHAT YOU NEED TO KNOW – PART 3 of 3: HUMAN DOSING AND CBD FOR PETS

Written by Augusta pharmacists Chris and Lee Davidson • NOTE: None of the information provided here is intended to be a claim that these products do or do not work for the uses listed. It is intended only to create awareness of what the available products are being suggested for and the research that is currently being done. This is a quickly changing area of medicine so it is recommended that you do your own additional research before choosing any of the products. Once someone has made an informed decision to take CBD after closely researching which brand they would prefer and which dosage form to take, the next big question should be about dosing. How much is recommended? That is the million dollar question! Since the FDA does not currently regulate CBD dosing (except in the case of the recently approved prescription product Epidiolex for two very specific types of childhood seizures) the dose for most conditions is open to discussion and interpretation. Each manufacturer will give you a different recommended basic starting point depending on their product. For example, one manufacturer will recommend a beginning dose of 2-3 mg per day, whereas another manufacturer might recommend beginning at 20-25mg per day. One recommends titrating the dose up to the maintenance dose, and another recommends a larger “loading dose,” and then dropping to a lower maintenance

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dose. (This likely has to do with how many of the cannabinoid varieties are present and if the product does or does not contain THC.) Even factoring in for the differences between the products themselves, the dosing for each individual person may be vastly different. Although each CBD manufacturer has slightly different dosing recommendations, the general range suggestions are similar. If you have never tried CBD before, most of the companies recommend beginning with a low dose – approximately 5 mg – and increasing the dose as needed in a stepwise fashion regardless of the indication. It is recommended to try the lower dose for 3-7 days and then slowly increase by 1-2 mg at a time until the desired effect is attained. (The following suggestions are for the zero-THC products.) For allaround basic health and wellness, a dose of 3-7 mg per day should do the job. The dose for basic anxiety and minor sleep issues ranges from 7-17 mg per day. For minor to moderate chronic pain, inflammation, and moderate sleep issues, you may need to try a total of 20-40 mg/day. More severe sleep disorders, including some narcolepsy, may require doses 40mg or higher. Severe chronic pain, such as that from rheumatoid arthritis or the like, may require doses of 25-50 mg or more. Getting into more severe issues such as Parkinson’s Disease or as an adjunct to certain seizure or psychiatric conditions may require doses of 50mg or more. An interesting note about how almost all CBD products are labeled: The bottles tend to state the total amount of CBD in the container. For example, Green Roads has the oils in 100mg, 250mg, 350mg, 550mg, 1000mg, 1500mg, and 3500mg bottles. The 100mg size is in a 15ml bottle, so it is a concentration of 7mg/ml. This bottle would be good for someone just getting started with CBD, or who only needs just a small amount per dose. At the other end of the dosing spectrum would be the 3500mg size in a 60ml bottle, a concentration of approximately 58mg/ml. Obviously THIS MONTH MARKS THE the higher dosage bottle is going to 13th ANNIVERSARY OF THE cost significantly more, but it would FIRST ISSUE OF THE be good for someone who is estabMEDICAL EXAMINER, lished on their dose who can easily PUBLISHED JULY 1, 2006. adjust for the number of milligrams they need. In both cases, the “recomTHANK YOU TO ALL OUR mended dose” is ½-1ml under the LOYAL READERS & ADVERTISERS! tongue once or twice a day. Sun Med Please see CBD page 2

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July12 19 by Daniel Pearson - Issuu