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Seed Grants - Opioid Reduction in Orthopedic Surgery (OREOS): A Feasibility Randomized Controlled Trial in Total Knee Replacement Patients
Opioid Reduction in Orthopedic Surgery (OREOS): A Feasibility Randomized Controlled Trial in Total Knee Replacement Patients
Primary Investigator: Harsha Shanthanna, MD, PhD, FRCPC
Start Date: 2022
Brief Overview and Progress to Date
The main objective of this pilot trial is to assess the feasibility of a multicomponent pathway on patients having elective total knee arthroplasty, while the clinical objectives are to determine the effects of the pathway on opioid-free pain control, persisting pain and opioid use, functional knee outcomes, quality of life, and return to function. Patients in the intervention group will undergo a multicomponent intervention pathway that will be facilitated by an intervention coordinator linking each patient and their surgical/ perioperative team. We have completed recruitment and surgery of all study patients and we are working on data collection to ensure minimal loss to follow up.
The trial aims to establish feasibility of a larger multi centred trial.
