20+20 Vision

Page 98

Larry Wald and the Three Traumas If you know Martinos researchers, you know they are often modest and even self-effacing about their accomplishments. It’s a part of their charm. In a recent conversation, MRI Core director Larry Wald framed his early days in the Center as a series of traumas. Whatever challenges he might have faced, he undoubtedly handled them with an endless reserve of skill and aplomb. Still, it’s fun to imagine those days as he describes them—as one fire after another begging to be put out, or maybe an eternal game of whack-a-mole—so we will indulge him in his humble retelling. Wald joined the Martinos Center in early 1998, after a stint as an instructor at McLean Hospital in Boston. When he arrived, he was named director of human imaging and tasked with maintaining the Advanced NMR-equipped MRI systems in Building 149, in the same spots where Bays 2 and 3 are today. But his tenure in this position would prove short lived; before long, Wald’s role in the Center would change in a somewhat dramatic fashion as the first of his three traumas befell him. Robert Weisskoff was the head of the MRI Core and chief magnetic resonance physicist at the Martinos Center and the former senior physicist at Advanced NMR Systems who had played an integral role in bringing to the Center the enabling technology for functional MRI. In short, he was an important and stabilizing presence in the Center. But within months of Wald’s arrival, he left his position to embark on a new adventure, going to business school and eventually establishing himself in the world of venture capital and private equity. Today, Wald admits that Weisskoff’s departure “caused a bit of turbulence.” Not because of any interpersonal conflicts or lingering resentment; only because he suddenly found himself in a significantly expanded role—he was now the MRI Core Director. This, alone, would have been a shock to the system. As it happened, though, the change also came at a critical juncture in the Center’s history. Maybe a month after Weisskoff left the Center, its Advanced NMR scanner began a descent into obsolescence. GE stopped providing regular service for the specialized resonant gradient coils used for fMRI, which were originally made and serviced by Advanced NMR. Finding spare parts grew more and more difficult, and the spare parts the researchers did find were often contaminated. The Center’s scanners were “slowly sinking under the waves, getting more and more unstable,” Wald says. This was the second of his three traumas. The Center continued for a time with a state-of-the-art GE scanner. It wasn’t

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Detecting Consciousness in Unresponsive Patients with COVID-19

3min
pages 212-213

Will Social Distancing Have a Lasting Impact on ‘Personal Space’?

4min
pages 208-209

AI Measures COVID-19 Lung Disease Severity on Chest X-Rays

3min
pages 204-207

The Martinos Center Responds

3min
pages 194-197

2020 (Introduction)

1min
pages 192-193

The Center’s Bruce Jenkins: Born to Be Wild

2min
page 191

The Secret Lives of Martinos Folk: Carol Barnstead & the Center’s cast of colorful characters

5min
pages 188-190

The State of the Center Today

1min
page 184

The Spark (Introduction)

1min
pages 182-183

Learning to See: AI Technique Dramatically Improves the Quality of Medical Imaging

3min
pages 180-181

Artificial Intelligence Improves Treatment Monitoring in Patients with Glioma

4min
pages 178-179

Artificial Intelligence (Introduction)

1min
pages 176-177

Structural Connectivity and Alzheimer’s Disease

1min
page 172

Buckle Up: With New Techniques, MRI is Faster than Ever Before

2min
pages 170-171

Studying Anxiety and Depression with Diffusion MRI

4min
pages 166-169

The Roots of Diffusion Imaging

3min
pages 164-165

Diffusion Imaging (Introduction)

1min
pages 162-163

The Secret Lives of Martinos Folk: Zeynab Alshelh fights stereotypes of women in Islam, one karate kick at a time

4min
pages 160-161

The Possible Role of Glow Sticks—Yes, Glow Sticks—in Treating Alzheimer’s

1min
pages 158-159

Imaging Interactions between Genes and the Environment

2min
pages 156-157

Moving Beyond Biopsy for Liver Fibrosis

3min
pages 152-154

Advancing PET Imaging with Quantitative Methods

1min
page 149

Imaging at the Molecular Level

4min
pages 146-148

Molecular Imaging (Introduction)

1min
pages 144-145

3 Things You Didn’t Know About David Cohen and MEG

3min
pages 142-143

MEG Method May Hold the Secret to Baldness

1min
page 140

Diagnosing and Treating Epilepsy, Other Disorders

2min
pages 138-139

Improving Communication Skills in Autism

3min
pages 136-137

The Music of MEG

4min
pages 128-131

MEG (Introduction)

1min
pages 126-127

The (Nearly) Lost Art of Scientific Glassblowing

3min
pages 124-125

The Road to MPI

3min
pages 122-123

Extremity Scanners and ‘Moving’ MRI

3min
pages 120-121

MRI at Bedside

3min
pages 118-119

New, Portable Scanner to Bring MRI to the Patient

3min
pages 116-117

Low-Field & Novel Imaging (Introduction)

1min
pages 114-115

The (Totally True) Legend of Thomas Witzel and the Ultrahigh-Field MRI Quench

3min
pages 112-113

Ultrahigh-field MRI and Multiple Sclerosis

2min
pages 108-109

7T MRI Memories

1min
pages 102-103

7T at the Martinos Center: An Origin Story

3min
pages 100-101

Larry Wald and the Three Traumas

4min
pages 98-99

Ultrahigh-Field Imaging (Introduction)

1min
pages 96-97

The Secret Lives of Martinos Folk: The Masked Scientist

3min
pages 94-95

Nutrition and Brain Growth in the Developing World

5min
pages 90-93

Estimating Tumor Boundaries with Fluorescence Lifetime Imaging

2min
pages 88-89

Maintaining Cerebral Blood Flow During Cardiac Surgery

3min
pages 86-87

Seeing the Light with Optical Imaging Technologies

6min
pages 80-85

Optics (Introduction)

1min
pages 78-79

The Secret Lives of Scientists: Anastasia Yendiki

2min
pages 76-77

'Women in Science' Group Tackles Sexism, Other Issues

4min
pages 74-75

Predicting Cognitive Decline in Alzheimer's Disease

2min
pages 70-71

The First 20 (Plus) Years of FreeSurfer

9min
pages 64-69

FreeSurfer (Introduction)

1min
pages 62-63

Meet the Neuronauts

3min
pages 60-61

Understanding the Patient-Clinician Relationship

2min
pages 58-59

What Is ‘Covert Consciousness’ and Why Is It So Important?

2min
pages 56-57

Eye-Contact Avoidance in Autism

3min
pages 54-55

The Neuroscience of Personal Space

5min
pages 52-53

Is Functional MRI the New X-Ray Vision?

3min
pages 50-51

Building 75 Opens Its Doors

1min
pages 46-47

Martinos Staff

1min
pages 44-45

In Memory of Athinoula

4min
pages 38-39

The Martinos Gift (Introduction)

1min
pages 36-37

Behind the Cover: The Story of the Original fMRI Image

3min
pages 34-35

Captivating Tales from the Pioneer Trail

1min
page 33

The ‘Unassuming’ Ken Kwong and a Pivotal fMRI Breakthrough

8min
pages 28-32

The Life and Science of Jack Belliveau

8min
pages 22, 24-27

The Foundations of Functional MRI

2min
pages 20-21

Functional MRI: Origins (Introduction)

1min
pages 18-19

A Brief History of the Charlestown Navy Yard

4min
pages 16-17

The Birth of a Center

7min
pages 10-13

The Early Years (Introduction)

1min
pages 8-9

Functional MRI: Applications (Introduction)

1min
pages 48-61

Message from the Director

2min
pages 6-7
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