SARMsPharm Therapy Shows Large Muscle Gains

SARMsPharm Therapy Shows Large Muscle Gains How you can big, strong muscles is long and requires hard work in a gym. But researchers may have discovered a shortcut where the muscles grow by themselves. Scientists have actually succeeded, through gene therapy, to increase the lean body mass and the effectiveness of macaque monkeys.

The experiment was simple enough, the researchers just injected the gene follistatin (FS344) straight into the monkeys right thigh muscles.

It's been shown that follistatin can block myostatin, a molecule that down-regulates musclegrowth, but strengthens tendons. Eight weeks after the injection the circumference of the monkeys right thigh muscles, had on average increased 15 percent compared with the left thigh. A study done on two of the monkeys revealed that musclestrength in the proper leg was increased by respectively 12 and 36 per cent compared to the untreated leg!

The Follistatin is injected through a viral vector, that's a Adeno Associated Virus used as a transport for the drug that Ligandrol for sale is injected.

It is a common method called Gene Therapy, and has been found in humans with other drugs.

The analysis on the monkeys showed no negative side effects.

This therapy has been developed for use in patients with severe muscle dystrophy and other muscle wasting disorders.

Clinical trials on humans are due to start in 2011 and Nationwide Childrens Hospital in Ohio has gained funding for the study. You can find numerous studies and clinical trials either underway or planned for treatment of muscle wasting disorders, among a few of the more interesting substances are Follistatin being an antagonist to Myostatin, Ostarine which is really a SARM(Selective Androgen Receptor Modulator) and happens to be in Human clinical trials by GTx Inc. and also another SARM beneath the codename BMS-564,929 which is being produced by Bristol-Myers Squibb.

The prospect of these substances to be abused by athletes has prompted the World Anti-Doping Agency to truly have a ban on SARMs since 2008.

Sofar only the substance known as "SARMs S4" (Andarine) has made it to the market, and has been used by a restricted amount of pro and amateur bodybuilders, it's anabolic effects are said to be moderate and it has been reported to own some temporary side effects, among which decreased night vision could be the more prominent.

The future of drugs developed for muscle wasting diseases are sure to be of interest for athletes and others wanting to gain the additional advantage.

Another 5-10 years will dsicover various substances turn out and some might be good replacements for Anabolic steroids.

These drugs will soon be available through the black market for pro and amateur athletes alike, with unprecedented anabolic effects and near to no negative side effects.