Marchesini Group_Process

PROCESS

Designed to provide the right mix

Index ABOUT MARCHESINI GROUP..................................................4 KEYPOINT................................................................................5 Turboemulsifiers, Mixers and Melters..................................6 Turnkey solutions.................................................................11 Cleaning systems.................................................................13 Tableting................................................................................16

Packaging solutions inspired by the extraordinary

OUR PRODUCTION PLANTS

Keypoint

We at Marchesini Group are proud leaders in manufacturing and integrating complete lines since 1974.

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Biplanetary mixer for maximum homogenization efficiency

Ergonomic design

System for integrated and optimized heating and cooling, to maximize energy savings

Efficiency and Accuracy

Water consumption optimization during washing

User Friendly solutions

To complete the range of production machines for the pharmaceutical industry, the Group production plants Dott. Bonapace and Dumek allow Marchesini Group to supply processing machines for different types of products such as solids, capsules, tablets and creamy products.

Continuous improvement of existing solutions and research of new products and processes is the base of our philosophy for the design of solutions able to satisfy customers’ needs.

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TURBOEMULSIFIERS, MIXERS AND MELTERS

Vacuum overpressure PHARMA-MEK | OPENABLE & TILTABLE Featured Model PHARMA-MEK 1000 with bi-planetary mixing unit

Vacuum turboemulsifiers suitable for processing liquid and creamy products.

Turboemulsifiers homogenizer

VESSEL • Openable lid • Tilting vessel up to 3000 • Parts in direct contact with product in AISI 316 stainless steel TEMPERATURE MANAGEMENT • Vessel with inner double jacket with water/thermic fluids for heating and cooling • Smart temperature control system (patented) for temperature curve design • Possibility to insert thermoregulation unit within machine guards (optional) VACUUM • Vacuum circuit with visual passage and liquid ring pump EQUIPMENT OF THE VESSEL • Funnel on the lid for auxiliary substances loading • Sight-port equipped with glass-wiper and light-port with momentary light on the lid • Tri-clamp connections and diaphragm valves on lid MIXER • Bi-planetary or slow coaxial mixing system (counter-rotating) • Mixing blade with optimized profile for the vertical movement of product, including PTFE scrapers • Variable speed of the Mixer through inverter TURBINE • Homogenizing turbine - rotor/stator type at the bottom of the vessel or external • Variable speed of the turbine through inverter VESSEL UNLOADING • Piston valve for the product unloading, placed at the bottom of the vessel

SUPPORTING STRUCTURE • AISI 304 stainless steel supporting structure with anti-vibration/self-levelling and adjustable support feet OPERATOR PANEL • Touch screen 12’’ operator panel with Siemens PLC • Digital visualization of the process parameters • Function for the continuous recording of process parameters: trends and datalogger (D-SCRIBA) • CFR Part 11, Active Directory and validation package (optional) ATEX CONFIGURATION • ATEX certification for internal Zone 1 with nitrogen inertization and external Zone 2 (optional).

RANGE 25-3000 litres

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TURBOEMULSIFIERS, MIXERS AND MELTERS

Vacuum overpressure PHARMA-MEK | OPENABLE

Vacuum overpressure PHARMA-FIX | FIXED LID & VESSEL

Featured Model PHARMA-MEK 1000 with DUAL TECHNOLOGY: Internal + External recirculation

Featured Model PHARMA-FIX 1000

Vacuum turboemulsifiers suitable for processing liquid and creamy products.

Vacuum turboemulsifiers suitable for processing liquid and creamy products.

VESSEL • Fixed vessel with openable lid • Parts in direct contact with product in AISI 316 stainless steel DUAL TECHNOLOGY • Either internal or external recirculation or a combination of both.

TEMPERATURE MANAGEMENT • Vessel with double jacket filled with water/thermic fluids for heating and cooling • Smart temperature control system (patented) for temperature curve design • Possibility to connect thermoregulation unit (optional)” VACUUM • Vacuum circuit with visual passage and liquid ring pump EQUIPMENT OF THE VESSEL • Funnel on the lid for auxiliary substances loading • Sight-port equipped with glass-wiper and light-port with momentary light on the lid • Tri-clamp connections and diaphragm valves on lid MIXER • Bi-planetary or slow coaxial mixing system (counter-rotating) • Mixing blade with optimized profile for the vertical movement of product, including PTFE scrapers • Variable speed of the Mixer through inverter TURBINE • Homogenizing turbine - rotor/stator type at the bottom of the vessel or external • Variable speed of the turbine through inverter

VESSEL • Fixed vessel with fixed lid • Parts in direct contact with product in AISI 316 stainless steel DUAL TECHNOLOGY • Either internal or external recirculation or a combination of both TEMPERATURE MANAGEMENT • Vessel with double jacket filled with water/thermic fluids for heating and cooling • Smart temperature control system (patented) for temperature curve design • Possibility to connect thermoregulation unit (optional) VACUUM • Vacuum circuit with visual passage and liquid ring pump EQUIPMENT OF THE VESSEL • Funnel on the lid for auxiliary substances loading • Sight-port equipped with glass-wiper and light-port with momentary light on the lid • Tri-clamp connections and diaphragm valves on lid MIXER • Bi-planetary or slow coaxial mixing system (counter-rotating) • Mixing blade with optimized profile for the vertical movement of product, including PTFE scrapers • Variable speed of the Mixer through inverter TURBINE • Homogenizing turbine - rotor/stator type at the bottom of the vessel or external • Variable speed of the turbine through inverter

RANGE 300-5000 litres

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TURBOEMULSIFIERS, MIXERS AND MELTERS

VESSEL UNLOADING • Piston valve for the product unloading, placed at the bottom of the vessel SUPPORTING STRUCTURE • AISI 304 stainless steel supporting structure with anti-vibration/self-levelling and adjustable support feet OPERATOR PANEL • Touch screen 12’’ operator panel with Siemens PLC • Digital visualization of the process parameters • Function for the continuous recording of process parameters: trends and datalogger (D-SCRIBA) • CFR Part 11, Active Directory and validation package (optional) ATEX CONFIGURATION • ATEX certification for internal Zone 1 with nitrogen inertization and external Zone 2 (optional).

VESSEL UNLOADING • Piston valve for the product unloading, placed at the bottom of the vessel SUPPORTING STRUCTURE • AISI 304 stainless steel supporting structure with anti-vibration/self-levelling and adjustable support feet OPERATOR PANEL • Touch screen 12’’ operator panel with Siemens PLC • Digital visualization of the process parameters • Function for the continuous recording of process parameters: trends and datalogger (D-SCRIBA) • CFR Part 11, Active Directory and validation package (optional) ATEX CONFIGURATION • ATEX certification for internal Zone 1 with nitrogen inertization and external Zone 2 (optional).

RANGE 25-10000 litres

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TURBOEMULSIFIERS, MIXERS AND MELTERS

Atmospheric pressure MIXER & MELTER Featured Model MELTER 50

Melters and mixers originally designed as machines for the oil phase preparation, when equipped with an adequate mixing system or turbine are turned into real units for products that do not require vacuum and pressure processing.

VESSEL • Vessel with parts in direct contact with product in AISI 316L stainless steel • Vessel with double jacket filled with water/thermic fluids (or single wall) • Lid in two parts with one openable side TEMPERATURE MANAGEMENT • Thermoregulation of the product MIXER • Vessel can be equipped with slow mixer anchor-shaped, fast mixer helix+cowless and/or turbine on the bottom VESSEL UNLOADING • Inclined bottom with a side-discharging valve • Conical bottom with central discharging valve (optional) STRUCTURE AND OPERATOR PANEL • Supporting frame on wheels or on feet.

• Control panel Siemens fixed to the frame • Batch management, CFR Part 11, Active Directory and validation package (optional)

RANGE 10-5000 litres

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Turnkey solutions

TURNKEY SOLUTIONS

Turnkey solutions We control every aspect of the design and production of our products, helping our customers to choose the solution best suited to their needs.

We can provide you a complete laboratory for the production of cosmetic products, optimizing space, consumption and production costs.

WE MEET YOUR NEEDS We realize platforms with access ladders and pallets loading/unloading bays, completely made of stainless steel AISI 304, that can support vacuum turboemulsifiers, mixers and melters through a single control panel that can control all the units.

We can supply steam generators, chiller units and piping for connecting the utilities to the machineries and provide a complete turnkey solution to our customers.

Cleaning systems 12

CLEANING SYSTEMS

Cleaning systems SEMI-AUTOMATIC CIP

Cleaning systems FULLY AUTOMATIC CIP

Featured Model SEMI-AUTOMATIC CIP SYSTEM

Featured Model FULLY AUTOMATIC CIP

Standalone or integrated system to manage the machine washing in a semiautomatic mode by setting an easy CIP program.

• High pressure recirculation pump • Automatic valves for water recirculation or discharge • Flexible pipe to connect mixer discharge with pump inlet • 300 lt. stainless steel tank with detergents manual addition (optional) • Conductivity sensor (optional)

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CLEANING SYSTEMS

Standalone fully automatic CIP fixed system to manage the washing in a fully automatic mode.

• Main skid to be located in technical room • Up to n°3 dosing pumps for detergents • Up to n°2 water storage vessels with self-cleaning • Steam or hot water exchanger for water heating • Sanitization, sterilization and drying modules (optional) • Possibility to execute riboflavin test on Dumek equipment (optional)

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TABLETING

Tablet pressing CPR-6 SE Featured Model CPR-6 SE

Bench top tablet press machine for small batches, designed for pharmacies, hospitals, universities and also R&Ds, in a word everywhere a small batch is needed.

• Solution for formulation development phase • Medium and high containment (isolator) solution • Standard punches type B or D • Dedicated software for supporting analysis of the data

Video

Tableting

OUTPUT Up to 2.500 tabs / h

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TABLETING

Tablet pressing CPR-18 SE

Tablet pressing CPR-22

Featured Model CPR-18 SE

Featured Model CPR-22

A bench top rotary tablet press machine for R&D applications, clinical testing and small production batches (laboratory batches).

Ideal for pharmaceutical and nutraceutical industries.

• Three different turrets available • Medium and high containment (isolator) solutions • Flexible and compact solution • Dedicated software for supporting analysis of the data

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TABLETING

• Three different turrets available • Solution for medium production batches • Dedicated software for supporting analysis of the data • Medium and high containment (isolator) solution • 3 different discharge chute available (production, sampling, discarded, ) • Solution for nutraceutical products

Video

Video

OUTPUT Up to 18.000 tabs / h

OUTPUT Up to 36.000 tabs / h

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TABLETING

Tablet press HIGH CONTAINMENT SOLUTION Featured Model HIGH CONTAINMENT SOLUTION

Rotary tablet press machine for R&D applications, clinical testing and small production batches. Digital parameter regulation enhances its efficiency and accuracy.

• Three different turrets available • Medium and high containment (isolator) solutions • Max Compression force 60 kN • Standard punches type euro B or D / TSM • Dedicated software for supporting analysis of the data • DUST TIGHT and IP 55 version also available

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The technical specifications given in this catalogue are subject to change without prior notice or liability.

Size range may vary in accordance with the different applications.

The Marchesini Group constantly updates its products to meet market needs.

Edition April 2026

Marchesini Group S.p.A. Via Nazionale 100 • 40065 Pianoro BO ITALY T +39 051 047 9111 sales@marchesini.com marchesini.com

MARCHESINI GROUP INSPIRED BY THE EXTRAORDINARY