Course Title/ Code Course Type Course Nature L-T-P-O Structure Objectives
Analytical Chemistry and Spectroscopy (CHH214) T & P Domain Core Hard (3-1-2-0) 1. To calculate concentration terms and their inter-conversion 2. To understand basic principles of UV-Vis spectroscopy and analyze spectra 3. To recognize and compare applications of inorganic polymers 4. To perform synthesis of inorganic compounds 5. To find out concentration of transition elements by titrations. ANALYTICAL CHEMISTRY AND SPECTROSCOPY THEORY (CHH214-T) SECTION A SCOPE AND INTRODUCTION TO ANALYTICAL CHEMISTRY Qualitative and Quantitative analysis, Classification of analytical methods, Classical and Instrumental methods. Sampling, Accuracy and Precision concepts, Selection of a sampling method for analysis, Applications of analytical methods in various fields: Organic, Pharmaceuticals, Electronic and Environmental. Chemical calculations of Expressing concentration of solutions –Normality, Molality, Molarity, Formality, inter-conversion between molality and molarityMole fraction, Weight ratio, Volume ratio, Weight to volume ratio, ppb, ppm, millimoles, milliequivalents. SECTION B SPECTROSCOPY Intoduction: Gerneral principles, introduction to absorption and emission spectroscopy, Electromagnetic radiation, regions of the spectrum, basic features of different spectrometers, statement of the born-oppenheimer approximation. UV-Vis Spectroscopy: Electronic transition (σ-σ*, n-σ*, π-π* and n-π*), relative positions of λmax considering conjugative effect, steric effect, solvent effect, red shift (bathochromic shift), blue shift (hypsochromic shift), hyperchromic effect, hypochromic effect (typical examples). Application of Woodward Rules for calculation of λmax for the following systems: α,β unsaturated aldehydes, ketones, carboxylic acids and esters; Conjugated dienes: alicyclic, homoannular and heteroannular; Extended conjugated systems (aldehydes, ketones and dienes); distinction between cis and trans isomers. Applications of UV-Vis spectroscopy for identification of simple organic molecules. SECTION C SEPARATION TECHNIQUES Solvent extraction: Classification, principle and efficiency of the technique. Mechanism of extraction: extraction by solvation and chelation. Technique of extraction: batch, continuous and counter current extractions. Chromatography: Classification, principle and efficiency of the technique. Mechanism of separation: adsorption, partition & ion exchange. Development of chromatograms: frontal, elution and displacement methods. Qualitative and quantitative aspects of chromatographic methods of analysis: IC, GLC, GPC, TLC and HPLC. Role of computers in instrumental methods of analysis. SECTION D PHYSICOCHEMICAL METHODS OF ANALYSIS Thermal methods of analysis: Theory of thermogravimetry Analysis (TGA), Theory of Differential thermal analysis (DTA), Theory of Differential Scanning Calorimetry (DSC), basic principle of instrumentation. Techniques for quantitative estimation of Ca and Mg from their mixture. Electroanalytical methods: Classification of electroanalytical methods, basic principle of pH metric, 32