Networks of Expertise on Cancer Prevention:
Creation to Implementation
JANE-2 is an ambitious Joint Action under the EU4Health Programme, stemming from Europe’s Beating Cancer Plan (EBCP), that aims at building seven new Networks of Expertise in the area of oncology, promoting cross-border collaboration through health networking.
€40.5 million in co-financing from the European Union
29 European Countries 7 Networks of Expertise across Europe 92 Affiliated Entities & 3 Associated Partners 4 Years
Work Package 8 is dedicated to establishing a pan-European Network of Expertise focused on personalised primary and secondary cancer prevention. By integrating genetic, lifestyle, and environmental factors, we aim to deliver evidence-based, tailored prevention strategies that empower citizens and support healthier communities.
Leader
Delia Nicoară
The Oncology Institute "Prof. Dr. Ion Chiricuţă" Cluj-Napoca (IOCN - RO)
Mission:
To improve health outcomes through interdisciplinary collaboration, aligning cutting-edge science, clinical practice and person-centred strategies for cancer prevention.
Brings together 30+ expert institutions across Europe.
Co-Leader
Stefania Boccia
Fondazione Policlinico Universitario Agostino GemelliUniversità Cattolica del Sacro Cuore (FPG, UCSC - IT)
Build interdisciplinary collaborations and tools for personalised prevention
Develop education, training, and health literacy programs
Align policies by using AI-driven analyses of omics and social determinants of health data
Raise public awareness, engage policymakers, and foster equitable access to personalised prevention
WP 8 - Scientific Core Tasks (T8.1–T8.5)
From Research to Real-World Impact
WP8 encompasses five core scientific tasks addressing risk prediction, policy integration, lifestyle factors, and targeted education to personalise and improve cancer prevention strategies across Europe.
T8.1 – Education, Training & Healt
iteracy
Identifies gaps in cancer prevention education and develops training programmes and twinning partnerships to improve healthcare professionals competence and public awareness.
Béatrice Fervers Unicancer - France
T8.2 – Health Policy ⚕️
Maps and supports the development of personalised cancer prevention policies by using AI-driven analyses of omics and social determinants of health data. Co-develops standards and indicators with policymakers, to guide equitable, evidenced-based personalised cancer prevention strategies across Europe.
T8.4 – Omics & Clinical Utility Mapping
Maps existing personalised primary and secondary prevention approaches focusing on clinical utility by conducting systematic literature reviews on omics science.
T8.3 – Lifestyle Aspects
Explores modifiable lifestyle factors using the exposome paradigm and develops integrated personal risk scores combining omics, lifestyle and environmental data.
T8.5 – Genetic & Epigenetic Risk
Identifies risk assessment and management approaches by conducting systematic reviews on moderate penetrance genes and (epi)genetic predictors of lung/pancreatic cancer, and through surveys on implementation of preventive strategies for BRCA/Lynch carriers.
Stefania Boccia
Daniela Turchetti
Denis Sarigiannis
NHRF - Greece
WP 8 Transversal Tasks (T8.6–T8.10)
Building a Sustainable and Collaborative Ecosystem
Transversal tasks underpin WP8 by ensuring quality, visibility, long-term impact, and strategic alignment with European and international initiatives.
T8.6 – Dissemination & Health Campaigns
Coordinates public awareness campaigns, digital outreach, and workshops. Engages healthcare stakeholders and mobilises community actors to promote prevention messages.
T8.7 – Evaluation
Monitors implementation, impact, and quality through defined KPIs, stakeholder feedback, and structured evaluation tools.
T8.8 – Governance
Establishes transparent, accountable, and efficient mechanisms for overseeing and coordinating the network. Aims to enhance collaboration, coordination and alignment among partners involved in personalised cancer prevention.
T8.9 – Sustainability
Facilitates long-term integration of personalised prevention into healthcare systems through policy embedding, resource mobilisation, and partnerships.
T8.10 – International Collaboration (JANE-2 EUnetCCC)
Strengthens synergies with EUnetCCC and other EU-level cancer projects, fostering crossborder knowledge exchange and prevention alignment.
Carmen Ungurean
NIPH - Romania
Torben Frøstrup Hansen
RSYD - Denmark
Per Magnus Mæhle
OUS -Norway
The Network of Expertise
Outputs, Outcomes and Impact
How the JANE 2 is advancing personalised cancer prevention across Europe
An EU-wide, interdisciplinary network that enables continuous collaboration beyond the duration of the project supporting policy, practice, and research.
Recommendations for Personalised Prevention
A set of evidence-based, expertdeveloped guidelines for preventing cancer before it starts — using individual risk profiles that include genetic, environmental, and lifestyle factors.
Empowers professionals to tailor prevention advice to individuals
Encourages citizens to act early based on personal risk Supports countries in building modern, data-driven prevention programs
Systematic
L ocal: Improved clinician capacity, education access, public awareness National: Policy recommendations, standardised approaches, equity focus European: Contributes to EU Cancer Plan , links national and european strategies for a unified approach. Global: International collaboration on screening standards and prevention alignment
Recommendations for Personalised Screening
Guidance for smarter, more targeted screening — integrating genetic risk, health inequities and access barriers.
Improves early detection for cancers like breast, cervical, and ovarian Increases screening efficiency and reduces unnecessary procedures Promotes equity by focusing on high-risk or underserved population
Twinning Programme on Personalised Prevention and Screening
Pilot collaborations between cancer centres to share expertise, build capacity, and co-implement screening strategies.
Strengthens institutional capacity in personalised prevention
Reduces gaps between countries in prevention delivery Accelerates uptake of innovative approaches across Europe
Contact & Communication
Channels:
Follow on LinkedIN: Network of Expertise on Personalised Cancer Prevention
Follow on Bluesky: JANE-2 Network of Expertise on Personalised Cancer Prevention
Building EU Networks of Expertise on Cancer Together
jane-2.eu
Views and opinions expressed are, however, those of the author(s) only and do not necessarily reflect those of the European Union or HaDEA. Neither the European Union nor the granting authority can be held responsible for them. EU4H-2023-JA-3-IBA – Joint Action JANE-2 – GA 101183265