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The most dangerous complication resulting from disturbed calcium phosphate metabolism is calciphylaxis. We also use third-party cookies that help us analyze and understand how you use this website. Daher sollten Probenentnahmen fur Knochenbiomarker bei nuchternen Patienten
durchgefuhrt werden. In this article the parameters considered standard are analyzed for their applicability to determination of bony metabolism. A loss of balance between bone formation and bone resorption can result either in osteoporosis or osteosclerosis. Bei Storungen dieses Prozesses kommt es durch verstarkten Knochenaufbau zur Osteopetrose, durch verstarkten Abbau zur Osteoporose. Emerging insights into the pathophysiology of osteoporosis. Abstract Renal osteodystrophy reflects a network of highly complex cellular components, and regulatory molecules, such as locally acting mediators including those revealing osteogenic, osteoclastic, calcifying and anti-calcification properties, which also interfere with cytokines. Gleichzeitig konnte dieses
Kanalprotein ein potenzielles Drug-Target sein. Gerat dieser Umbau aus dem Gleichgewicht, kann einerseits Osteoporose oder andererseits Osteosklerose resultieren. Download citation Published: 30 October 2008 Issue Date: November 2008 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Ionenkanale bilden selektive Poren in zellularen Membranen, deren Offnungszustand durch verschiedene Faktoren reguliert wird kann. At present calcium phosphate metabolism due to chronic renal failure much more concerns problems of heterotopic calcification resulting in an increased cardiovascular morbidity and mortality, and accelerated arteriosclerosis (e.g. by transdifferentiation of vascular smooth muscles cells) than instability of bone structures. The osteoblasts are responsible for the synthesis and the osteoclasts for resorption of the bone. Man findet sie in verschiedenen zellularen Kompartimenten, deren Funktion vom pH-Wert abhangig ist. Kreuzreaktionen mit Abbauprodukten konnen dabei falsche Messwerte hervorrufen. It is mandatory to procure user consent prior to running these cookies on your website. Schlusselworter: Osteosklerose, Remodeling, Osteoklast, Chloridkanal, Protonenpumpe Summary Molecular Mechanisms of Regulation of Bone Density by Osteoclasts The skeleton is subject to a lifelong remodeling process by a complex interaction of osteoblasts and osteoclasts. Freyschmidt View author publications You can also search for this author in. These cookies do not store any personal information. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren. This category only includes cookies that ensures basic functionalities and security features of the website. They may help to assess bone turnover in the diagnostic work-up and aid decision-making as well as selection of pharmaceutical therapy options. F, Hoffman DL et al (1980) Treatment of primary osteoporosis with fluoride and calcium. Abstract In order to accommodate individual load, the skeletal system is in a continual state of change. But opting out of some of these cookies may affect your browsing experience. Recent publications on therapy response have shown that biochemical markers of bone turnover are valuable tools for the evaluation of therapy success in individual osteoporosis patients and the assessment of bone mineral density gain during therapy. Dieser Prozess wird auch als enchondrale Ossifikation bezeichnet. Viele davon sind noch in klinischer Erprobung oder derzeit wissenschaftlichen Fragestellungen vorbehalten.
A loss of balance between bone formation and bone resorption can result either in osteoporosis or osteosclerosis. Dementsprechend kann es leicht zugefuhrt werden, um eine Verbesserung herbei zu fuhren. Kreuzreaktionen mit Abbauprodukten konnen dabei falsche Messwerte hervorrufen.
Freyschmidt View author publications You can also search for this author in F, O’Fallon WM (1990) Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Download citation Published: 04 May 2016
Issue Date: June 2016 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Download citation Published: 12 July 2007 Issue Date: July 2007 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. A finely adjusted interplay between molecular mechanisms leads, via cytokines, hormones and growth factors, to an homeostasis in bone metabolism. Emerging insights into the pathophysiology of osteoporosis. Peichl MSc View author publications You can also search for this author in. Gleichzeitig konnte dieses Kanalprotein ein potenzielles Drug-Target sein. We also use third-party cookies that help us analyze and understand how you use this website. PICP hat demgegenuber weniger Bedeutung erlangt, ist fur spezielle Fragestellungen (auch aus dem nichtosteologischen Bereich) allerdings weiterhin interessant. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren. Schett Authors E. Neumann View author publications You can also search for this author in. Viele davon sind noch in klinischer Erprobung oder derzeit wissenschaftlichen Fragestellungen vorbehalten. Schwetz Authors B. ObermayerPietsch View author publications You can also search for this author in. Schett View author publications You can also search for this author in. Disturbances of this process lead via increased bone resorption to osteoporosis, and via increased synthesis to osteopetrosis. Dr. M. Ketteler, Klinikum Coburg, fur wertvolle Diskussionen zur Thematik. Es wird vermutet, dass ToulouseLautrec an dieser Erkrankung litt. Man findet sie in verschiedenen zellularen Kompartimenten, deren Funktion vom pH-Wert abhangig ist. Dose-response relationships in early postmenopausal women. F, Hoffman DL et al (1980) Treatment of primary osteoporosis with fluoride and calcium.
Schlusselworter: Osteosklerose, Remodeling, Osteoklast, Chloridkanal, Protonenpumpe Summary Molecular Mechanisms of Regulation of Bone Density by Osteoclasts The skeleton is subject to a lifelong remodeling process by a complex interaction of osteoblasts and osteoclasts. Bei Storungen dieses Prozesses kommt es durch verstarkten Knochenaufbau zur Osteopetrose, durch verstarkten Abbau zur Osteoporose. Gerat dieser Umbau aus dem Gleichgewicht, kann einerseits Osteoporose oder andererseits Osteosklerose resultieren. Investigation of hereditary forms of this condition revealed that acid secretion plays a central role for osteoclast function.
These cookies will be stored in your browser only with your consent. Download citation Published: 12 July 2007 Issue Date: July 2007 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Bei Storungen dieses Prozesses kommt es durch verstarkten Knochenaufbau zur Osteopetrose, durch verstarkten Abbau zur Osteoporose. Download citation Published: 04 May 2016 Issue Date: June 2016 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Disturbances of this process lead via increased bone resorption to osteoporosis, and via increased synthesis to osteopetrosis. Metaanalysis of the efficacy of hormone replacement therapy in preventing osteoporosis in postmenopausal women. This category only includes cookies that ensures basic functionalities and security features of the website. Gleichzeitig konnte dieses Kanalprotein ein potenzielles Drug-Target sein. Freyschmidt View author publications You can also search for this author in. Dr. M. Ketteler, Klinikum Coburg, fur wertvolle Diskussionen zur Thematik. Abstract Renal osteodystrophy reflects a network of highly complex cellular components, and regulatory molecules, such as locally acting mediators including those revealing osteogenic, osteoclastic, calcifying and anti-calcification properties, which also interfere with cytokines. These cookies do not store any personal information. The most dangerous complication resulting from disturbed calcium phosphate metabolism is calciphylaxis. Download citation Published: 08 October 2014 Issue Date: September 2014 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. PICP hat demgegenuber weniger Bedeutung erlangt, ist fur spezielle Fragestellungen (auch aus dem nichtosteologischen Bereich) allerdings weiterhin interessant. Antiresorptiva vermindern Knochenstoffwechselmarker, insbesondere Resorptionsmarker, osteoanabole Ansatze erhohen Knochenstoffwechselmarker, insbesondere Formationsmarker. F, Hoffman DL et al (1980) Treatment of primary osteoporosis with fluoride and calcium. Abstract Laboratory analyses of biochemical markers for bone and mineral metabolism can play a key role in the assessment of patients with osteoporosis. Es wird vermutet, dass Toulouse-Lautrec an dieser Erkrankung litt. Abstract In order to accommodate individual load, the skeletal system is in a continual state of change. A finely adjusted interplay between molecular mechanisms leads, via cytokines, hormones and growth factors, to an homeostasis in bone metabolism. Investigation of hereditary forms of this condition revealed that acid secretion plays a central role for osteoclast function. Schwetz Authors B. Obermayer-Pietsch View author publications You can also search for this author in. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren. Less severe osteosclerosis is usually caused by osteoblast dysfunction, whereas reduced or absent bone resorption by the osteoclasts can lead to severe, even lethal, variants of this disorder. Man findet sie in verschiedenen zellularen Kompartimenten, deren Funktion vom pH-Wert abhangig ist. Viele davon sind noch in klinischer Erprobung oder derzeit wissenschaftlichen Fragestellungen vorbehalten. Dieser Prozess wird auch als enchondrale Ossifikation bezeichnet. Schlusselworter: Osteosklerose, Remodeling, Osteoklast, Chloridkanal, Protonenpumpe Summary Molecular Mechanisms of Regulation of Bone Density by Osteoclasts The skeleton is subject to a lifelong remodeling process by a complex interaction of osteoblasts and osteoclasts.
Abstract Renal osteodystrophy reflects a network of highly complex cellular components, and regulatory molecules, such as locally acting mediators including those revealing osteogenic, osteoclastic, calcifying and anti-calcification properties, which also interfere with cytokines. Peichl MSc View author publications You can also search for this author in. Gleichzeitig konnte dieses Kanalprotein ein potenzielles Drug-Target sein. Investigation of hereditary forms of this condition revealed that acid secretion plays a central role for osteoclast function. Dementsprechend kann es leicht zugefuhrt werden, um eine Verbesserung herbei zu fuhren. F, Hoffman DL et al (1980) Treatment of primary osteoporosis with fluoride and calcium. Schwetz View author publications You can also search for this author in. Verminderung des Vitamin-D-Status mit moglichen Konsequenzen bis hin zur Osteomalazie bei jedem individuellen Patienten bekannt sein. A loss of balance between bone formation and bone resorption can result either in osteoporosis or osteosclerosis. Dieser Prozess wird auch als enchondrale Ossifikation bezeichnet. Metaanalysis of the efficacy of hormone replacement therapy in preventing osteoporosis in postmenopausal women. Man findet sie in verschiedenen zellularen Kompartimenten, deren Funktion vom pH-Wert abhangig ist. Es wird vermutet, dass Toulouse-Lautrec an dieser Erkrankung litt. This category only includes cookies that ensures basic functionalities and security features of the website. But opting out of some of these cookies may affect your browsing experience. These cookies will be stored in your browser only with your consent. Kreuzreaktionen mit Abbauprodukten konnen dabei falsche Messwerte hervorrufen. These findings greatly contributed to our understanding of the regulation of bone density by osteoclasts and may result in new therapeutic strategies. Download citation Published: 04 May 2016 Issue Date: June 2016 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Emerging insights into the pathophysiology of osteoporosis. Freyschmidt View author publications You can also search for this author in. We also use third-party cookies that help us analyze and understand how you use this website. Download citation Published: 08 October 2014 Issue Date: September 2014 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Less severe osteosclerosis is usually caused by osteoblast dysfunction, whereas reduced or absent bone resorption by the osteoclasts can lead to severe, even lethal, variants of this disorder. These cookies do not store any personal information. PICP hat demgegenuber weniger Bedeutung erlangt, ist fur spezielle Fragestellungen (auch aus dem nichtosteologischen Bereich) allerdings weiterhin interessant. The osteoblasts are responsible for the synthesis and the osteoclasts for resorption of the bone. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Download citation Published: 30 October 2008 Issue Date: November 2008 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article.
In: Genant HK, Jergas M, van Kujik C Vertebral fractures in osteoporosis. Schett Authors E. Neumann View author publications You can also search for this author in. Freyschmidt View author publications You can also search for this author in. Man findet sie in verschiedenen zellularen Kompartimenten, deren Funktion vom pH-Wert abhangig ist. Ionenkanale bilden selektive Poren in zellularen Membranen, deren Offnungszustand durch verschiedene Faktoren reguliert wird kann. This category only includes cookies that ensures basic functionalities and security features of the website. Defects in three totally different proteins that are involved in the acid secretion mechanism as well as a protease that is essential for collagen degradation cause different subforms of osteosclerosis. Bei Storungen dieses Prozesses kommt es durch verstarkten Knochenaufbau zur Osteopetrose, durch verstarkten Abbau zur Osteoporose. Viele davon sind noch in klinischer Erprobung oder derzeit wissenschaftlichen Fragestellungen vorbehalten. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience. A clinical hygienic study with a review of the literature and some experimental investigations. We also use third-party cookies that help us analyze and understand how you use this website. They may help to assess bone turnover in the diagnostic work-up and aid decision-making as well as selection of pharmaceutical therapy options. Download citation Published: 12 July 2007 Issue Date: July 2007 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. The osteoblasts are responsible for the synthesis and the osteoclasts for resorption of the bone. It is mandatory to procure user consent prior to running these cookies on your website. Gerat dieser Umbau aus dem Gleichgewicht, kann einerseits Osteoporose oder andererseits Osteosklerose resultieren. Dieser Prozess wird auch als enchondrale Ossifikation bezeichnet. Gleichzeitig konnte dieses Kanalprotein ein potenzielles Drug-Target sein. Schett View author publications You can also search for this author in. Disturbances of this process lead via increased bone resorption to osteoporosis, and via increased synthesis to osteopetrosis. These cookies will be stored in your browser only with your consent. The most dangerous complication resulting from disturbed calcium phosphate metabolism is calciphylaxis. PICP hat demgegenuber weniger Bedeutung erlangt, ist fur spezielle Fragestellungen (auch aus dem nichtosteologischen Bereich) allerdings weiterhin interessant. These cookies do not store any personal information. Download citation Published: 08 October 2014 Issue Date: September 2014 DOI: Share this article Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Investigation of hereditary forms of this condition revealed that acid secretion plays a central role for osteoclast function. Daher sollten Probenentnahmen fur Knochenbiomarker bei nuchternen Patienten durchgefuhrt werden.