What You Need to Know About THCV Isolate THCV Isolate, which is structurally and linguistically similar to THC, produces a variety of effects that differ significantly from those of its better recognised relative. This interesting cannabinoid, which is typically found in trace amounts in cannabis, has begun to garner a lot of attention, motivating breeders to develop cultivars with higher levels of THCV Isolate.
What Exactly Is THCV? While THC is a CB1 receptor agonist, THCV is an in inverse agonist, meaning it binds to the same receptor but has the opposite pharmacological action. In contrast to THC, it is non-psychoactive and suppresses the munchies, with some study indicating that it can even cancel out the effects of THC. In one study, cannabis users were given an oral dose of THCV shortly before being injected with THC, and none of them got very high[i]. However, because THCV is present in such low concentrations in most cultivars, ingesting enough of it to counteract the effects of THC in the real world is difficult. THCV also binds to CB2 receptors, raising the possibility that it could help reduce inflammation, manage pain, and potentially protect against dementia.
The Advantages of THCV Isolate Because it lowers hunger, THCV Isolate is being researched as a possible therapy for obesity. It has been demonstrated in studies to help reduce food intake and promote weight reduction, and human experiments have revealed that it modifies the brain's response to food[ii].