Knipper Health - Providing Solutions Brochure 2023

PROVIDING SOLUTIONS for your Specific Brand Challenges

SEAMLESS PATIENT INITIATION

IMPROVED PATIENT ACCESS

PRODUCT AVAILABILITY TO THE POINT OF CARE

Creating the shortest path between patient and therapy.

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Whether you are in the process of commercializing a brand or have a well established brand Knipper Health can provide a full range of solutions for every phase of the product life cycle.

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Pre-Approval

Product Pre-Launch/ Launch

Growth Stage

Loss of Exclusivity/ End of Life

Solution for Every Phase Of Product Life Cycle

KnippeRx Custom Pharmacy Solutions

Knipper Third Party Logistics

Knipper Marketing & Sample Management

Clinical Trial Support Rx Network Planning

Distribution Planning & Clinical Site Stocking

Clinical Trial Support Contact Center Marketing Material

COMMERCIAL Specialty Lite Hub Lite Direct to Patient - Cash

3PL Distribution/ Stocking Kitting

End-to-End Sample Management

NON-COMMERCIAL Free Trial QS/Bridge COMMERCIAL Specialty Lite Hub Lite

Trade Warehousing, Distribution Inventory Management

Order to Cash End-to-End Solutions

Warehouse & Logistics Contact Center Solutions Marketing Material White Space Support End-to-End Sample Management Warehouse & Logistics

NON-COMMERCIAL PAP, PRP QS/Bridge, Clinical Study

Reverse Logistics Repackaging Relabeling

Contact Center Solutions

COMMERCIAL Specialty Lite White Label Pharmacy Direct to Patient - Cash

Trade Warehousing, Distribution Inventory Management

End-to-End Sample Management

NON-COMMERCIAL Free Trial Voucher

© 2023 Knipper Health. All Rights Reserved.

Order to Cash End-to-End Solutions Reverse Logistics Repackaging Relabeling

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Marketing Material White Space Support

Warehouse & Logistics Contact Center Solutions Marketing Material White Space Support

The Most Expansive Reach in the Industry

35+

Years in Business

25,000+

Sales Reps Supported

132+

Life Science & Device Companies

600,000+

HCPs Reached per Year

Surgical Institutions Supported

Seat Contact Center

For over 35 years, Knipper Health

850,000

Sq. ft. Space

4,000+

650+

4,500,000+ Shipments Annually

Units Shipped per Year

Order Accuracy

3,500,000+

has earned the distinction of being a well-recognized leader in healthcare solutions serving the pharmaceutical, biotechnology, and medical device industries.

Through three distinct service offerings: Knipper3PL Third Party Logistics, KnippeRx Custom Pharmacy Solutions, and Knipper Marketing and Sample Management (MSM), we provide solutions for your brand, throughout the entire product life cycle.

2 Billion+

99.9984%

Dispenses Annually

1 Million+

Cold-Chain Units Shipped

1 Billion

Business Rule Checks

5 Million

Phone Calls per Year

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© 2023 Knipper Health. All Rights Reserved.

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Patient Access Ensuring patient access to your product from launch – and throughout the product’s life cycle.

KnippeRx Custom Pharmacy Solutions help your brand overcome patient access obstacles throughout the product life cycle from launch to end-of life.

We provide commercial solutions that offer patients non-traditional direct access to their therapies by delivering a more convenient and personalized patient experience while strengthening your market position.

© 2023 Knipper Health. All Rights Reserved.

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COMMERCIAL SOLUTIONS Specialty Lite Services Through state-of-the-art technology, KnippeRx has automated specialty pharmacy solutions, enabling lower WAC brands to benefit from traditional specialty pharmacy services. > Highly Personalized Patient Service

> Highly Scalable Infrastructure

> Integrated BV, PA, and Appeals Support

> Robust Data and Analytics

> Experts in Removing Barriers to Access

> Experienced, Knowledgeable and Trusted Partner

> Exceptional Clinical Expertise

> Affordable Programs Customized to the Needs of Your Brand

> Flexible Program Models

Increase Greater Access to Therapy

Healthcare Provider

Concierge Service Home Delivery Rx Management Tools

Direct to Patient Cash Programs Many mature products enjoy considerable brand loyalty but struggle to maintain market share in highly competitive categories with shrinking formulary coverage.

Manufacturers

Offer a one-stop solution to ensure patients receive the therapies they choose to take at a price they can afford.

> Serving the needs of small, medium, and large pharma-solutions built to scale with manufacturer’s needs

Providers

Lowers the administrative burden on office staff by providing a hassle-free and exceptional experience, to ensure the patients receive the brands prescribed.

> From single brand initiatives to multi-brand solutions for mature product groups > Highly automated solutions designed to fit the objectives of your brand while keeping the focus on the patient experience

Patients

Patient-centric assistance with access to therapy, highly knowledgeable clinical staff, convenient home delivery and assistance with medication adherence.

White Labeled Pharmacy Deliver white labeled pharmacy services under your brand to better serve your patients. When you partner with KnippeRx for your white labeled pharmacy needs, you get access to: > Full-service mail-order pharmacy services

> Central fill capabilities

> Robust APIs that support telehealth integration

> Call center service

> Patient access support capabilities

> Clinical support

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NON-COMMERCIAL SOLUTIONS At KnippeRx, our Non-Commercial Pharmacy Services provide a range of access channels that help patients get their prescribed medication, regardless of their circumstances

Patient Assistance Programs > Challenges with scalability and affordability of PAP programs is driving the need for more efficient, innovative solutions that reduce cost and improve the patient and HCP experience. > KnippeRx has developed the “Rx Cares Technology Ecosystem” a comprehensive end-to-end platform based on the latest technologies and industry insights. > Eliminating complex integrations across multiple providers > Streamlining and automating application processing > Aligning business rules with industry norms > Maximizing scalability to better manage intake spikes > Addressing higher than anticipated annual enrollments > Ensuring compliance with state and federal regulations providing clear visibility to impactors and metrics which effect overall cost to the business

“Rx Cares Technology Ecosystem” is a comprehensive end-to-end platform based on the latest technologies and industry insights. > Online and Mobile Patient & HCP Intake > CRM Based Case Management > Omni-Channel Patient & HCP Support > Integrated Hub Life Services > Clinical Care & Training > Ambient & Cold-Chain Patient Dispensing > API Based 3rd Party Integration Capability > Advanced Reporting and Analytics Dashboards > HCP Stock Replenishment via Knipper 3PL

© 2023 Knipper Health. All Rights Reserved.

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NON-COMMERCIAL SOLUTIONS

Product Replacement Programs A patient may need an urgent replacement drug or medical device, however, manufacturers often find the replacement process costly and time-consuming.

At KnippeRx, we provide small- and large-scale Patient Product Replacement services with a purpose-built CRM solution that integrates with manufacturers’ Medical Information team to: > Receive approved patient requests > Quickly deliver the replacement to the patient or provider > Patient-labeled dispensing via the KnippeRx pharmacy > Prescriber stock replenishment via Knipper’s integrated 3PL

Quick Start Program:

When prior authorizations or pre-approvals are required, patients may experience coverage decision delays.

When an insurance coverage delay occurs and the Program eligibility requirements are met, the Quick Start Program can provide a one-time supply of their medication to the patient.

Bridge Program:

The Bridge Program provides continuity of care for patients who experience an unexpected gap or loss of insurance coverage. Patients can be provided with a supply of their medication until they obtain insurance coverage.

Clinical Trial Dispensing:

Licensed to dispense in all 50 states, we can help you; > Manage the distribution and dispensing of clinical trial or study medication > Process requests for double-blind, placebo-controlled trials > Design and manage clinical trial transition programs > Support uninterrupted treatment as patients transition to commercial dispensing With our Knipper Integrated 3PL Services, we also offer inventory management, site stocking, secondary repackaging & relabeling, and product serialization.

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Product Availability Your partner in secure management and distribution, commercialization and special processing needs in life sciences.

COMPREHENSIVE 3PL SERVICES Knipper 3PL offers a complete range of safe, scalable, compliant and cost-effective services and solutions that deliver unsurpassed performance, value and results. Most importantly, our 3PL services are purpose-built to achieve your specific goals and needs.

Expert 3PL Distribution & Logistics • Inventory, storage management

• DSCSA full end-to-end serialization solutions

• Automated pick and pack (Perfect Pick®), Pick to Light

• DEA Controlled • Cold chain

Comprehensive 3PL Services • Product launch commercialization, advanced data and analytics

• Repacking/kitting/relabeling • Reverse logistics

• EDI comprehensive reporting • 3PL Consignment and Flash Title models

• Tamper seals

3PL Customer and Financial Services • Account set-up and management

• Contract management

• Full order-to-cash

• DSCSA Buyer support

It’s Built for You

Our Leadership & Experience

Your Passionate Partner

The flexible, tailored solutions of Knipper 3PL integrate an agile, responsive business model with trusted, proven distribution services and an innovative suite of combined technology capabilities t o drive performance, efficiencies and cost-controls.

Dedicated solely to the Life Sciences industry for more than 35 years, Knipper is an industry leader in trade distribution, free goods distribution, dispensing and sampling.

We work closely with your team providing a holistic, consultative approach to address brand challenges and build advocacy, while providing value-added insights and actionable data in a timely, results-driven manner.

© 2023 Knipper Health. All Rights Reserved.

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PRODUCT AVAILABLILTY

Operations Control Systems

Distribution Support Services

• Integrated order management ( OMS)

• Traditional 3PL order-to-cash a nd fulfillment

• Integrated logistics systems ( WMS, TMS, labor, billing, cost accounting)

• State Licensing Support • Alternative Distribution Models a nd Direct to Patient Models I ntegrated with our Specialty P harmacy KnippeRx

• Light-directed picking, P erfect Pick • Trade partner management for r apid dock-to-stock times

• Government Pricing Support • Repackaging/ Kitting/ R elabeling

• Robust and configurable ERP s ystems that support higher- than-industry standard focus on c ollecting and reporting quality assurance statistics

• Reverse Logistics • DSCSA Full End-to-End Serialization Services

• Advanced, fully transparent r eporting platform

Warehousing Facilities

Solid Regulatory Compliance

• 850,000 square feet overall in m ultiple facilities

• FDA Audits covering cGMP, m edical device quality systems, P DMA, and 21 CFR Part 11 systems compliance

• 36,200 square feet of dedicated r efrigerated warehouse space

• Licensed wholesaler/third-party l ogistics provider in all 50 states, D C, Puerto Rico and Guam

• 27,500 square feet of dedicated s pace for DEA controlled s ubstances Schedule III, IIIN, I V, & V

• FDA-registered Repackager/ Relabeler facilities, c GMP-compliant for medical foods, drugs, and devices

• Security: Onsite security guards, Card access control systems, B iometric access for DEA cages, Video Surveillance

• Registered with the DEA as an I mporter and Exporter of S chedules III, IIIN, IV, and V controlled substances

• Warehousing and inventory m anagement support for ambient, c old-chain, and frozen products, including quarantine

• Registered with the DEA as a D istributor of Schedules III, IIIN, IV, and V controlled substances

• Automated temperature and humidity control

• AICPA SOC certified • NABP-accredited Drug Distributor (wholesaler/3PL, formerly VAWD)

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KNIPPER SEAL™

Secure Exchange of Authentic Logistics Knipper Secure Exchange of Authentic Logistics (SEAL) includes an a rray of overlapping systems and processes to ensure the secure h andling of your products from receiving through distribution and a fter delivery to your buyer.

• Tightly Controlled and Validated Handling

• Layers of Physical Security

• Process Focused on Serialization

• Enhanced DEA Cage Security

• Encrypted Data Exchange

• Cyber Security

• GxP Processes

• Controlled and Recorded Environment

• Authentication at Receiving

End to End Secure Exchange of Authentic Logistics in Life Sciences

© 2023 Knipper Health. All Rights Reserved.

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SERIALIZATION OFFERINGS

Multiple Serialization Offerings from basic serialization support to where Knipper 3PL can manage All DSCSA needs.

KNIPPER EASI™

Exchange of Aggregated Serialized Items Service to aggregate your unaggregated products for DSCSA

KNIPPER TRAC™

Transit Refrigeration Assurance Controls

KNIPPER PAL™

Portal for Authentic Logistics Web Browser Access for Your Buyers to DSCSA Transaction Documents

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Patient Initiation

PATIENT INITIATION SOLUTION

A Patient Initiation Solution for Every Phase of Your Brand’s Life Cycle

Pre-Approval

Product Pre-Launch/ Launch

Growth Stage

Loss of Exclusivity/ End of Life

Reach HCPs and patients as soon as possible after approval

Ensure sampling program is achieving your desired ROI (real-time, advanced data visibility and analytics into entire sampling program)

Develop and implement a successful sampling program (Direct To Practitioner, Direct To Representative Hand Carry, Direct To Patient)

Reach white space territories with product messaging, marketing material, and samples for no access practitioners

Ensure entire sampling program is always PDMA compliant (HCP compliance, sales representative compliance)

Augment commercialization efforts with additional marketing programs (print literature programs and product and collateral kitting)

Sample inventory management

Protect brand profitability and market share at product maturity and loss of exclusivity

Field sales support

Flexibility and adaptability to react to market changes

© 2023 Knipper Health. All Rights Reserved.

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SAMPLE MANAGEMENT

The Industry’s Only Fully Integrated End-to-End Sample Management Program Knipper Contact Center Interface

Direct To Practitioner (DTP)

Integration with Knipper Health’s Contact Center that performs practitioner and sales rep outreach.

An E-sampling portal for practitioners to request product samples, support materials, and literature.

Direct To Representative (DTR)

Advanced Data and Analytics

An intuitive business rules-based sales rep portal for ordering of samples and product literature.

An onboard reporting dashboard providing real-time access to your sample-related data in an easy-to-use interface.

Direct To Consumer (DTC)

Sample Accountability (SA)

Integrated patient portal whereby consumers can order OTC medications direct from the manufacturer.

A built-in, rock-solid sample accountability module for ensuring compliance with PDMA guidelines.

Direct To Hospital (DTH) An integrated platform for Hospitals that don’t dispense PDMA regulated samples to enroll and request Free Trial product.

Client Reporting Portal One overarching, real-time view of all program data, inventory, and activity through a single integrated reporting portal.

Sample Accountability and Reconciliation

Direct To Representative (DTR)

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Direct To Practitioner (DTP)

Inventory Management

Advanced Data and Analytics Trends and Dashboards

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SOLUTIONS FOR EVERY PHASE Pre-Approval

Pre-Launch

Launch

Create Demand

Objectives

Phases

Introduce Product to Market

Major Activities

Clinical Studies

Educate and Influence Providers and Patients | Generate and Reinforce

Contact Center

Knipper Health Solutions

Direct Marketing

› Print Services

End-to-End Sample Management and Literature

For Sponsors, CROs, and Recruitment Agencies Phase II, III, IV › Investigator Recruitment

Contact Center

› Candidate Recapture

Warehousing, Distribution, and Fulfillment

HCP Connect › Territory Warming › Inside Sales › Telemarketing › Teledetailing

Assure HCP › HCP Validation Program

› Patient Screening

› Direct Mail & Literature Fulfillment › Product/Supply Distribution › Appointment Reminders

HCP Office Sample Readiness Program

Knipper Direct

© 2023 Knipper Health. All Rights Reserved.

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E IN THE PRODUCT LIFE CYCLE Market Penetration

Maturity

Patent Expiration

Establish Loyalty Capitalize on Market Potential Extend and Reposition

Expand Brand Reach and Increase Targets Market Demand | Cover Vacant Territories and White Space | Maximize Marketing and Promotional Spend Exploit Switch Potential Defend Brand Position HCP Connect/HCP ReConnect

White Space Coverage › Inside Sales › Telesampling

› Direct Mail and Literature Fulfillment

› Fully Integrated Sample Management Program

Sample Accountability › PDMA Compliance

› Teledetailing

› Product and Collateral Kitting

› Direct To Physician (DTP)

› Direct To Rep (DTR)

› Direct to Hospital (DTH)

› Rep Hand Carry Services

Audit Inventory Management System (AIMS) › Sample Reconciliations › Field Audits › Field Close-outs › Field Inventory

› National Rep Storage Facility Program

Knipper Advanced Data Analytics and Business Reporting Architecture (KADABRA) › Unique Data Reporting Environment to Create Visual Analytics › HIPAA Compliant, Direct To Patient Platform, E-commerce, Direct To Consumer (DTC) Purchase of OTC Medications, Products, and Devices 23

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SYNERGY WITH KNIPPER SERVICES TO MAXIMIZE SUCCESS BENEFITS OF CHOOSING KNIPPER HEALTH As your single source provider DRIVING PRODUCT DEMAND

Product Sampling • Maximize HCP experience, awareness and trust

• Maximize patient experience and positive feedback through expanded usage

OVERCOMING BARRIERS TO ACCESS • Initial MC coverage gaps • Unique patient education on product usage instructions • Ensuring patient compliance • HCP confidence patient will get therapy

• Seamless office staff admin to ensure patient gets therapy • Deamless patient experience in obtaining Rx • Initial product retail availablilty • Exceptions: Patient Assistance Programs; Affordability

LOGISTICS SOLUTION • Launch solution experience • End-to-end solution which optimizes efficiencies • Centralized full service 3PL logistics capability

• Ability to service emerging to large manufacturers, specialty products, branded-generics and devices • Cost efficiency/control

• One Company • One Warehouse • One Contract • One Quality Agreement • One Audit • One Primary Point of Contact • One supplier from pre-approval through LOE • Extensive therapeutic areas of expertise • Extensive KPIs • Extensive offerings for emerging to Fortune 500 Companies • Extensive access to offering based SMEs for best practices • Extensive efficiencies resulting in real savings • Extensive rebate programs • Extensive, real-time reporting and analysis for data transparency BONUS • Access to the UPS Worldport • Tailored Programs to meet the manufacturer’s needs • Access to a flex force of workers for acute urgent needs • Ease of Integration • Proactive compliance coverage • Scalability to meet your increasing business needs • Flexibility to adapt to your changing environment

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