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July 26 2016 Ozark Life Publishing, LLC
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Vol 2 Issue 30
jacklb@tidbitsofnorthcentralarkansas.com
TIDBITS® AVOIDS
POISON by Janet Spencer In the 1940s there were only 60 possible poisons that could be used to kill a person. Then came the chemical explosion, and by the mid-1970s there were some 5,000 poisons which could be combined in different ways to produce perhaps a quarter of a million different deadly doses. Come along with Tidbits as we avoid poisons! BOTULISM • In a small town in Germany in 1735, thirteen people shared a sausage. A few hours later, they all became sick. Six died, and the other seven took months to recover. The strange illness was named after the Latin word for sausage— botulism. • The botulism toxin is seven million times more powerful than cobra venom. One ounce, properly distributed, could wipe out everyone in the U.S. The botulism organism evolved on this planet some two billion years ago. At that time, there was no oxygen on Earth. • Today botulism lives indefinitely as a dormant spore in air and dirt, surviving temperatures between absolute zero and boiling. When it finds the right conditions— plenty of food and an absence of oxygen— it multiplies, releasing toxins. Deaths from botulism are particularly worrying for home canners. If a jar has not been heated high enough or long enough, the botulism organism will thrive. THE FACTS BEHIND POISONS • A poison called saxitoxin found in contaminated seafood is so deadly that 2/10ths of 1 milligram, or 1/100th of a drop, can kill a full grown man through paralysis. HOW can such a small amount of a substance kill such a large organism? One way is through enzyme sabotage. • An enzyme is a catalyst for biochemical reactions. In very tiny amounts, an enzyme has a great effect on a living system. The enzyme maltase takes water and other materials and turns them into glucose. The enzyme cytochrome turns oxygen in the blood into a usable form. There are thousands of enzymes in the human body. A single liver cell has about 50,000 enzymes. Find a substance that turns off a single important enzyme, and you have a major monkey wrench in the machinery of the body. A dose of cyanide weighing as much as a postage stamp will shut down the cytochrome enzyme. There will be plenty of oxygen in the blood stream, but no way to get it into the cells without cytochrome. • Another type of poison is one that affects the nervous system. All important signals in the body are sent through the biological wiring of the nerves. Many substances cause the signals to fail: either the “phone” is always busy; or the bell fails to ring; or the phone is answered but the voice is so distorted it can’t be understood. Important messages such as “Breathe!” fail to get through. Curare, a resin from tropical plants, does just that, by relaxing the body to such an extent that breathing stops, the same way saxitoxin works as well. IT’S A FACT • The oleander is a shrubby tree that is so poisonous that single leaf is fatal to man. At a tragic beach party, a dozen people used oleander sticks to roast hot dogs
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