IRJET- Automated Detection of Diabetic Retinopathy using Compressed Sensing

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AUTOMATED DETECTION OF DIABETIC RETINOPATHY USING COMPRESSED SENSING Sreelakshmi B1, Mr.S.Mohan2, Dr.V.Jayaraj3 1PG

Scholar,Dept. of Electronics &Communication Engineering,Nehru Institute of Engineering & Technology 2Assistant Professor,ECE Department Nehru Institute of Engineering and Technology, 3Professor & Head,ECE Department Nehru Institute of Engineering and Technology ---------------------------------------------------------------------***--------------------------------------------------------------------is to assert, vessel pixels are to be recognized from neighbourhood to vicinity and merged collectively Retinal diseases are the major reason to damage the visual parts of the eye .The main aim of the proposed work is to find ultimately. 2d, due to the fact that of this main issue out the disease such as increase in blood pressure, diabetic moving, the training information, for that reason, can retinopathy, glaucoma, retinal tear and retinal detachment be augmented from a hundred to a hundred thousand, and cardio-vascular diseases. These diseases can be found by which ensures the effectiveness of deep network the extracted blood vessels. Hypertension in the body leads to coaching. 0.33, the correct system offine tuning the the damage in the retinal blood vessels. Tear in the visual pretrained semantic segmentation model has made the parts may leads to the loss of visual perception in the human regional segmentation assignment so much simpler. beings. Diabetic retinopathy diseases can be identified at the This pre-expert semantic segmentation mannequin is early stages by using image processing techniques. Thus the the completely convolutional variant of AlexNet, which early stage of rectification may leads to smaller damage than good performs the pixel-to-pixel and end-to-finish the risky ones. Thus the proposed work leads to the identification of retinal diseases with the certain level of segmentation. In the following sections, this paper will accuracy and sensitivity. additional present and talk about the implementation of the proposed process.The retinal vasculature has Key Words: Diabetic Retinopathy,Segmentation, been mentioned

Abstract - Eye diseases are rapidly increasing day by day.

Compressed Sensing,Classification

2.LITERATURE SURVEY: 1.INTRODUCTION

In an attempt to provide a tremendously correct and robust automatic retinal blood vessel segmentation method, this paper, for this reason, proposes an innovative supervised method to extract retinal vessels utilising deep studying tactics. More principally, the proposed method has applied the absolutely convolutional community, which is most of the time used to perform semantic segmentation undertaking, with transfer studying. Deep studying is an development of man-made neural networks, such as extra layers that let higher stages of characteristic abstraction and elevated predictions from information(2). Exceptionally, the convolutional neural network has proven to be a powerful software for quite a lot of of pc imaginative and prescient tasks comparable to photo classification and segmentation.

Recently, scientific picture evaluation organizations across the world are rapidly coming into thisfield and

More commonly, training a convolutional neural community requires big numbers of labeled training data, which is someway very tricky to realize in the medical domain where the proficient annotation is steeply-priced and the ailments are infrequent. For a project such like the retinal blood vessel segmentation, the whole number of the retinal color graphics from all the four databases is 133, which is a long way far from the learning requirement of the fully convolutional community. Nevertheless, with transfer learning, the convolutional neural community models pre-trained from nor[1] mal picture dataset, such as ImageNet , can be used for the new clinical venture at hand. There are three progressive features which have eventually made this proposed work triumphant. First, the proposed procedure has shifted, or in one more phrase, simplified the normal retinal vessel segmentation quandary from full-dimension photograph segmentation to regional vessel detail awareness. This Š 2019, IRJET

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making use of convolutional neural networks and other deep studying methodologies to a vast style of functions, and distinctive results are rising continuously (3).The totally convolutional community, proposed by using the pc imaginative and prescient staff of the tuition of California, Berkeley (4), is derived from the convolutional neural network, which, in concept, is on the whole constructed from a number of convolutional layers (5) and then followed by means of a number of entirely linked layers as in a general multilayer neural network. The principal function that makes a entirely convolutional network special from the convolutional neural community is the transformation of all wholly connected layers into convolution layers .It was way of which, a absolutely convolutional community is equipped to operate on an input of any measurement, and produces an output of corresponding spatial dimensions. In this case, some classification networks, such as the AlexNet (6), can be used for the end-to-finish, pixels-to-pixels for semantic segmentation, as a substitute of outputting the classification prediction scores. Within the work of Shelhamer et al. (7), the fully convolutional variant of AlexNet excels the entire other brand new works with out further machinery, which is consequently applied in the proposed work along with the transfer finding out methodology.Switch studying is the perfect answer when there have inadequate paper is as follows.

Section2will introduce the retinal image databases and the associated works. Part three will exhibit the proposed implementation of knowledge augmentation, the training of the utterly convolutional community, and publish-processing.

Figure 1.Basic block of image processing The block diagram of the proposed work is as follows.

Figure.2 Proposed block diagram A) IMAGE ACQUISITION: Retinal fundus images are the interior surface of the eye. It specifies opposite portion of lens include retina, optic disc, macula, fovea and posterior pole. These images should examine

3.PROPOSED WORK

and verified by ophthalmoscopy.

Image processing consists of various stages of processing. The main stage of image processing consists of image acquisition, pre-processing, segmentation, feature extraction and classification.

Figure.3 Input image Š 2019, IRJET

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B) PRE-PROCESSING: Pre processing stage consists of color conversion and filtering process.The input retinal images can be in the form of RGB images.These RGB images are converted into gray scale images.RGB images are converted into gray scale images due to the elimination of hue and saturation of the input images.

Figure.4 Green channel extraction This histogram equalization is used to equalize the intensity level of the converted gray-scale image.

Figure.3 Gray-scale conversion C) MEDIAN FILTER The median filter works by moving through the image pixel by pixel, replacing each value with the median value of neighbouring pixels. The pattern of neighbours is called the "window", which slides, pixel by pixel over the entire image. The median is calculated by first sorting all the pixel values from the window into numerical order, and then replacing the pixel being considered with the middle (median) pixel value. It is a nonlinear digital filter used to remove some noise in the image.

Figure.5 Histogram equalization E) MORPHOLOGICAL OPERATIONS There are several morphological operations present in image processing techniques.The main morphological operations used in the proposed work is opening,closing,top hat and binarization.

OPENING: Opening of the binary image is used to carried out the extraction of minute blood vessels within the fundus images.

Figure.4 Filtered image D) CHANNEL EXTRACTION This stage is used to separate the green channel of the fundus image.

Figure.6 Opening

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F) Compressed Sensing

I) BINARIZATION:

Compressive Sensing (CS) has attracted considerable attention in areas of applied mathematics, computer science, and electrical engineering by suggesting that it may be possible to surpass the traditional limits of sampling theory. CS is the theory of reconstructing large dimensional signals from a small number of measurements by taking advantage of the signal sparsity. CS builds upon the fundamental fact that can represent many signals using only a few non-zero coefficients in a suitable basis or dictionary. CS has been widely used and implemented in many applications including computed tomography, wireless communication, image processing .

Gray scale images are converted into binary-scale as their pixels value ranges from 0’s and 1’s.These pixel value is used to separate the meaningful parts from the unnecessary parts in the fundus image.

Figure.9 Binary image

G) OSTU SEGMENTATION

J) CLASSIFICATION:

OD Is the largest bright circle in the Image.

OD Detection allows eliminating the background and its destructive effects on the proposed method. Morphological operations are applied to get better quality image After the image enhancement the reconstructed image consist only the brighter pallets or regions with higher intensities. i.e. OD and exudates lesions. The morphological reconstruction operation enhances the compactness of brightly illuminated regions that include bright lesions, OD and contrast variations around the blood vessels.

From the extracted blood vessels we can able to classify the artery veins of the fundus retinal images.These extracted blod vessels is used to classify the person having the cardiac disease or normal.This classification is carried out using SVM classifier.

H) EXTRACTION OF TEXTURE FEATURES GLCM can be an m x n x p array of valid gray-level co occurrence matrices. Each gray-level cooccurrence matrix is normalized so that its sum is one. Properties can be a commaseparated list of strings, a cell array containing strings, the string 'all', or a space separated string. They can be abbreviated, and case does not matter. A Gray Level Co-Occurrence Matrix (GLCM) has information regarding the position of pixels possessing similar gray level values.

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Figure 9 Segmentation

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K) CLASSIFIERS The classification process is carried out using PNN classifiers.training and testing of retinal images is carried out using Neural Network (PNN).The PNN classifiers consists of 10,000 neurons and 3 hidden layers.

Figure.13 Sensitivity plot

Figure.10 classification 4 PERFORMANCE MEASURE: Performance measure is the calculation of accuracy,sensitivity,specificity.Accuracy,sensitivity,spe cificity can be calculated from the true positive and true negative values of the classified and non-classified images.

Figure.14 Specificity plot 5 CONCLUSION Thus the eye disease of the human are recognized using the image processing techniques which executes the accuracy range of 90% and the error rate will be lesser.

Figure.11 Performance measure

6 FUTURE WORK: Many retinal disease will be found using these image processing technique.In the future work,many disease are found at the lesser time.This will be used for the real time analysis.This will be used for analysis and diagnosis of retinal images.

REFERENCES: Abdurrazaq, I., Hati, S., Eswaran, C., 2008.

Morphology approach for features extractionin retinal images for diabetic retionopathy diagnosis. In: Proceedings of th International Conference on Computer and Communication Engineering 2008.ICCCE08: Global Links for Human Development. pp. 1373–

Figure.12 Accuracy plot

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1377.http://dx.doi.org/10.1109/ICCCE.2008.458083 0.

(2), 600– 16.http://dx.doi.org/10.1016/j.cmpb.2011.08.009.F u, H., Xu, Y., Wong, D.W.K., Liu, J., 2016. Retinal vessel segmentation via deep learning network and fullyconnected conditional randomfields. 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI) 698– 701.http://dx.doi.org/10.1109/ISBI.2016.7493362.

Greenspan, H., van Ginneken, B., Summers, R.M., 2016. Guest editorial deep learning in medical imaging: overview and future promise of an exciting new technique. IEEE Trans. Med. Imaging 35 (5), 1153– 1159.http://dx.doi.org/10.1109/TMI.2016.2553401. arXiv:1603.05959.

Al-Diri, B., Hunter, A., Steel, D., Habib, M., Hudaib, T., Berry, S., 2008. Review–a reference data set for retinal vessel profiles. In: 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE. pp. 2262– 2265.http://dx.doi.org/10.1109/IEMBS.2008.46496 47.

Azzopardi, G., Strisciuglio, N., Vento, M., Petkov, N., 2015. Trainable cosfirefilters for vessel delineation with application to retinal images. Med. Image Anal.

19 (1), 4657.http://dx.doi.org/10.1016/j.media.2014.08.00 2.

Jiang, Z., Yepez, J., An, S., Ko, S., 2017. Fast, accurate and robust retinal vessel segmentation system.

Biocybern. Biomed. Eng. 37 (3), 412– 421.http://dx.doi.org/10. 1016/j.bbe.2017.04.001.

Z. Jiang et al. Computerized Medical Imaging and Graphics 68 (2018) 1–15 Ordonez, R., Massin, P., Erginay, A., Charton, B., Klein, J.-C., 2014. Feedback on a publicly distributed database: the messidor database. Image Anal. Stereol. 33 (3),231– 234.http://dx.doi.org/10.5566/ias.1155.

Kohler, T., Budai, A., Kraus, M.F., Odstrcilik, J., Michelson, G., Hornegger, J., 2013.Automatic noreference quality

Deep learning–MIT technology review.https://www.technologyreview.com/s/5136 96/deep-learning/. Fraz, M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A., Owen, C., Barman, S.,2012a. Blood vessel segmentation methodologies in retinal images–a survey. Comput. Methods Programs Biomed. 108 (1), 407– 433.http://dx.doi.org/10.1016/j. cmpb.2012.03.009.

Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G., Barman, S.A., 2012b.

An ensemble classification-based approach applied to retinal blood vessel segmentation. IEEE Trans.

Biomed. Eng. 59 (9), 2538– 2548.http://dx.doi.org/10.1109/TBME.2012.220568 7.

Fraz, M.M., Barman, S.A., Remagnino, P., Hoppe, A., Basit, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G., 2012c. An approach to localize the retinal blood vessels using bit planes and centerline detection.

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