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Introducing Controlled Drugs into the EoE Adult Critical Care Transfer Service Laura Coslett- Lead Pharmacist Critical Care Cambridge University Hospitals NHS Foundation Trust (CUH)

Introduction • The East of England Adult Critical Care Transfer Service (ACCTS), hosted by CUH, serves 18 hospitals across the region, 24/7. • Operational Base in at an off-site location. • ACCTS facilitates timely transfer of critically ill adults who require urgent escalation for specialist services, as well as repatriation and load-levelling transfers • Set up in Dec 2021. Phase 1 implemented non-controlled drug medications only- including storage at base location, stock management, drug transfer bags, and safe prescribing documentation • National recommended formulary for ACCTS also includes controlled drugs (CDs) Aim of Phase 2 Implement secure controlled drug management and storage at the off-site base location and develop approved SOPs to facilitate use during transfers. All must comply with legal requirements and Trust policies, to ensure robust clinical governance.

Rationale for CDs in ACCTS For controlled drugs that belong to the referring hospital- unopened vials, or syringes filled with prepared CD medications but NOT connected to the patient must NOT be accepted by ACCTS – This would technically constitute illegal supply of controlled drugs. Additional CD infusions may be required during patient transit if longer journey time, or clinical scenario requires additional agents. Outcomes anticipated from Phase 2 → Protect ACCTS clinical staff from legal perspective → Robust audit trails for CD use within ACCTS → Optimise patient care and safety in the high-risk transfer setting

Methodology Stakeholder Engagement ‘Supporters’ • ACCTS Leads- Consultant, Nurse and Pharmacist service leads • ACCTS clinicians providing service day-to-day (end-users) (??) • Consultant pharmacist for critical care Need Agreement and buy-in from • Estates/minor works team • Security Services • Pharmacy Transformation Project Manager • Dispensary Services • Courier services  Chief pharmacist- CD Accountable Officer  Associate Chief Pharmacist (manages risk registers)  Medicines Safety Committee

Reflections & Learning Barriers encountered Input and agreement of numerous stakeholder • Complex to collaborate and communicate • Different professions, with different needs and priorities • Different schedules of stakeholders • Clinicians running services based across region, not just CUH Onerous Process • Unavoidable- strict legal and governance requirements • Inflexible legality vs practicality of use in critical scenarios • Negotiation to agree processes and accept risks (risk registers) • Success dependent on no ambiguity • Install infrastructure and agree processes prior to implementation • Off-site base location Niche of ACCTS • Extensive explanation and rationale to non-critical care stakeholders • Complicates collaboration • ‘backwards and forwards’ of questions and drafts • Unique circumstances- distinct from critical care units and acute ambulances • Relatively new service- new working relationships

Perceived low urgency for change • Service in place since 2021 without CDs • Need and Benefits of this service development are hard to ‘sell’ • Adds to workload of end-users

Results Remains a ‘Work in Progress’ • Physical infrastructure in place • Policy remains under development. Not yet approved by CDAO/Medicines Safety/ senior pharmacists • Outstanding ‘sticking points’: • CD registers and documentation for: • Base cupboard stock • CD transfer bag stock • signing whole bags in and out at start and end of transfer • Allowance for storage in locked but unmanned ambulances Ordering and Delivery • Stock ordered via controlled drug order book to CUH inpatient pharmacy. Delivered by courier using locked-box process

CD Stock cupboard • Stock received into CD stock cupboard and signed into CD stock register

• Learning sought from transfer services in other regions, and local Paediatric Retrieval Service

Transfer of cupboard stock to CD drug transfer bag

Policy development

• Stock signed out of CD stock cupboard register • Move CD from stock cupboard to drug transfer bag

• Detailed, specific description of each aspect: • ordering, delivery, base storage, record keeping, stock checking, movement of stock, administration, destruction, audit • Draft written and circulated for comment- multiple ‘rounds’

Physical Infrastructure • • • •

Delegated to those best able to coordinate and action Installation of cupboards, keysafes, swipecard access at base CD registers for base CD cupboard and for CD transfer bags Secure storage in ambulances

CD drug transfer bag • Stock signed into CD drug transfer bag CD register • Bag sealed with a tag to show complete and checked • CD drug transfer bag stored in CD cupboard when not in use during transfer •When CD drug transfer bag required for use, whole bag signed out of bag register

CD administration • CD drug transfer bag seal broken and CD administered to patient • Any remainder destroyed in CD destruction kit and disposed of in waste for incinceration on arrival at receiving hospital and documented in patient record

CD keys stored in a key safe (PIN code access) within a CD cabinet with swipe access changing key safe PIN quarterly Key cupboard is separate to the CD cabinet in which the CDs are stored

Documentation • Record dose administered against patient name in CD drug transfer bag CD register • Document in the next row any part dose that was destroyed and not used

Restock CD drug transfer bag and re-seal

References and Acknowledgements NHS England and NHS Improvement Transfer Service Toolkits for Adult Critical Care to Support the National Transfer Services June 2021 The Faculty of Intensive Care Medicine & Intensive Care Society. Guidance On: The Transfer of the Critically Ill Adult, 2019 Cambridge University Hospitals NHS Foundation Trust Controlled drugs policy. Version 29; Approved August 2023 EoE ACCTS Leads Anne Booth, Hannah Donald. CUH Consultant Pharmacist Critical Care David Sapsford. Transformation Project Manager, Pharmacy Gail Garood.


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