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Welcome

Index

We had a tremendously positive response to the peptide article in the last Aging Matters™ magazine. As I stated in that magazine; “you’re going to hear a lot more about peptides.” In fact, I ventured to be so bold as to suggest that they will shortly become the focus of the antiaging fraternity.

Welcome -Phil says thanks for finding the time

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GHRP performance -the growth hormone peptides

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The world’s first designer antiaging therapy -What stimulates the growth of hair?

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So to keep my promise, you don’t have to wait long to learn more about peptides - because this issue looks at the performance of the GHRPs, the ‘growth hormone releasing peptides.’ It’s a nice follow on to Dr. Walker’s interview about sermorelin that featured in the issue 2, 2012 Aging Matters™ magazine. As growth hormone itself has become difficult to obtain in recent years, the GHRPs look set to become its natural alternative. We’ve even included an article about the growth factors for hair too, so you can know what has been proven to make hair grow faster, thicker and stronger. Finally, we realised that Professor Ana Aslan started her experiments with Gerovital-H3®, (the world’s first designer antiaging supplement), in 1953. Thus 2013 is its 60th anniversary, so we asked Dr. Mircea Dumitru, (Ana Aslan’s own physician) to remind us about the research and what it still stands for today.

The hair growth factors -Find out what’s new

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Dr Dean answers your questions

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Featured products -Best sellers and new items

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Testimonials & Explanations -Nice people, nice comments

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Complete product A-Z list and prices -Find everything in-stock here

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Condition cross-reference list -find the right product for you Contact details -Get in touch with IAS today

Phil Micans, MS, PharmB Editor, Aging Matters™ Magazine

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Tomorrow’s treatments today ™ IAS is dedicated to helping you access the world’s latest commercially available supplements- to give you and your family real choices in health and wellness. IAS promises you:

• Product quality: We only stock the best quality products. With the

right materials and formulation you are more likely to get the results you desire.

• Original brands: We have the original brands - i.e. the same ones used in the clinical trials. These brands are used by top health professionals.

• Choice: The largest range of medicines, hormones and supplements. If you are looking for things that use words like bioidentical, efficacy and synergy then you’ve come to the right place.

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IAS supporting, sponsoring, exhibiting and lecturing at key venues. You can meet us in person and see what we believe in.

Declaration: The IAS Aging Matters™ magazine focuses on the latest international nutritional, hormonal and drug therapies to help combat the signs of aging. These signs include the physical, mental and internal changes consisting of the diseases and disorders such as cancer, arthritis and senile dementias etc. However, the main focus is upon the prevention of such aging diseases and disorders for the ‘healthy-aging’ individual. Copyright 2013: All copyrights are acknowledged. Whilst every effort has been made to ensure accuracy, no responsibility can be accepted for illustrations, photographs, artwork or advertising materials while in transmission or with the publisher or their agents. Disclaimer: All educational information is offered under IAS terms and conditions. This information does not replace the advice of your physician and restrictions may apply in some countries. The opinions expressed by the writers may not be those of IAS or the magazine. All prices shown are in US Dollars and are for reference purposes only and they do not include taxes (where applicable), nor do they include shipping & handling fees. Prices, conditions and terms are subject to change without notice.

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A lot of people reading this are I am sure, aware of the ‘power’ of growth hormone (GH); a hormone that is secreted by the pituitary gland (see figure 1). GH is popular by those interested in antiaging medicine, especially since Dr. Daniel Rudman’s landmark published article in 1990 in which it was stated; “growth hormone reversed aspects of aging in some individuals by as much as 20-years.” (1) What Rudman discovered was that by injecting his patients, (aged between 61 and 81) with recumbent human GH, (which remember in the late 1980s had only just recently become commercially available via newly developed production methods), that there were many reversed ‘consequences’ of aging. Benefits included more elastic and thicker skin, greater hair growth rate and quality, enhanced feelings of wellbeing and of course, perhaps the most famous attributes- decreased body fat levels and more lean muscle mass. 4

Figure 1: The pituitary gland in relation to the brain.

But as Dr. Richard Walker discussed with me in his interview regarding sermorelin last year (2); today we know that there are some ‘issues’ surrounding GH- when it is used in its recombinant form via subcutaneous injections; these include: • GH needs to be injected to be effective- not everyone wants to inject daily. • GH is somewhat temperature sensitive and needs to be stored in the fridge.

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• GH creates a negative feedback upon the pituitary gland, which means that if levels are not administered or monitored properly, then it could shut down/ reduce one’s own endogenous production of GH. • GH administered as a bolus injection does not mimic the natural pulsate release of GH, but rather produces a large bell curve in blood after administration. • GH injections remain relatively expensive. • GH has become a controlled substance in many countries. This means that its possession without a prescription can be considered to be a felony, and laws regarding import and export require import certificates to be supplied before it can be exported. On top of all this, MasterCard and Visa are now refusing to accept credit card payments for controlled substances, (and some other non-controlled medicines too!) Thus, in this last section, I have explained to you why GH has disappeared from most pharmacy sites. But not all hope is lost, since there are genuine GH precursors known as Growth Hormone Releasing Peptides (GHRPs) that are real-world alternatives.

IGF-1 Just before we move onto the GHRPs, mention should be made of IGF-1 (insulin like growth factor), which has been documented by Dr. Richard Lippman in his articles on the IAS website (3). IGF-1 is considered to be the ‘active’ agent that instructs cells to start ‘burning’ fat reserves. Indeed, the laboratory measure for determining the blood level of GH actually ‘looks’ for the levels of IGF-1. When IGF-1 levels are high then so have been GH and vice versa. In Dr. Ronald Klatz’s book; ‘Grow young with HGH’ (4) -published in 1998, I was quoted in it as saying of IGF-1; “that it will be the GH of choice in a few years’ time.” My thinking was that as IGF-1 became commercially available its price would begin to drop dramatically, (as had been the case with GH). Well, we’re now 15-years on from that statement and today there are a few commercially available IGF-1 products on the market, but unfortunately whilst their price has declined significantly, they remain expensive, so alas IGF-1 still remains the domain of the dedicated elite. Figure 2: Dr. Ronald Klatz’s book, Grow Young with HGH, released in 1998. So what else has recently become commercially available that looks promising to improve GH secretion?

GHRPs to the rescue! Ghrelin, a name derived from ‘growth hormone release inducing’ is a substance that stimulates growth hormone stimulatory receptors or GHSR, (5, 9). Ghrelin is produced primarily in the stomach and upper intestines (6) – but note that whilst GHSR’s are concentrated in the pituitary and hypothalamus, they are also widely distributed in central and peripheral tissues, thus helping to explain the diverse action of GH on the body (6, 10). But the problem with ghrelin is that it makes you hungry! In fact, it has been dubbed ‘the hunger hormone’ (7) - and there are many blogs on the internet that report this ‘side effect.’ This effect has also been published as occurring in both humans and animals (8). Ghrelin levels are high before eating increasing appetite and low after eating (see figure three). Ghrelin stimulates the appetite with the purpose of increasing the intake of food and promoting the storage of fat. So when ghrelin levels are high, we feel hungry. After we eat, ghrelin levels fall and we feel satisfied. Thus ghrelin may not be the supplement of choice for those wishing to lose weight, although it may be the one for those who want the desire to eat more! However an analogue of ghrelin, known as GHRP2 can realise the GH benefits of ghrelin without triggering any significant hunger pains (11).

Figure 3: The relationship between ghrelin and leptin before and after eating. Leptin and ghrelin have a ‘teetertotter’ relationship. When leptin levels rise, ghrelin levels fall. Likewise, when ghrelin levels rise, leptin levels fall.

GHRP2 clinically studied One placebo controlled study with GHRP2 (12) on 94 healthy individuals (male and female) aged between 40 and 70 years of age took various measures including waist and hips and ratios, total body composition (fat, water, bone and muscle mass), and forced lung capacity at its commencement. The subjects received either 10 ml of GHRP2 or a placebo each morning for 90 consecutive days. At the end of the study it was shown that those using GHRP2 improved their IGF-1 levels, from an average (pre-study) of 103.54 ng/ml to an average of 120.47 ng/ml (post study), thus clearly indicating that GH levels had been improved; however those using placebo had no significant changes in their IGF-1 (hence GH) levels. These improved GH levels did, (as expected) in the GHRP2

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patient group alter various physical parameters. For example, total body fat decreased on average by 9.14% with visceral fat levels decreasing on average by 14.27% (with no significant changes in the placebo group).

fibers were denser even 12 weeks after surgery in those who used GH. It was stated that progressive insufficiency of GH during aging may contribute to periodontal disease and tooth loss.

At the same time, muscle mass (as lean body mass) increased on average by 5.37% in the GHRP2 group; plus, forced lung capacity was increased on average by 16.61% (and again there no significant changes in the placebo group).

Therefore, GHRP2 supplementation could benefit the maladaptive effects of sarcopenia on an individual’s body composition and extend good dental health.

All these positive changes to these aging biomarkers corroborate findings from the studies that utilized GH injections.

GHRP2 synergy

Side effects Few side effects were noted in the study (12), with just some soft stools and some upset stomachs recorded. There was also an increase in the total blood platelet count, but the values remained within the normal clinical range. Animal studies regarding the mutagenicity of GHRP2, as well as its LD50 and various genotoxicity tests have been undertaken (13, 14, 15, 16, 17). None of these studies have shown any reason for concern, despite doses having been administered as high as 2000 mg per Kg bodyweight for 2-days and at 50 mg per Kg bodyweight for 90 consecutive days. Compare this with a typical recommended dose for humans at 4 mg (total bodyweight) per day! It is worth noting that one quite unusual study administered GHRP2 to children for 8 consecutive month; its outcome lacked any significant side-effects or toxicities (18). Another children reference also showed safety after 12 months of GHRP2 administration BID, (J Pediatr Endocrinol Metab. 2003 Sep; 16(7):981-5).

Uses GHRP2 is clearly a useful adjunct to boost GH levels. Therefore, perhaps its most direct application is to assist in the agerelated disorder of sarcopenia. Sarcopenia is the loss of lean body mass. Surprisingly, muscle loss can begin early in life, even by 25-years of age. Clinical studies that measure the excretion of creatinine, (a measure of muscle content) note decreases of 50% between the ages of 25 and 70. This fact highlights that the degradation of muscle exceeds its synthesis past young adulthood. Clearly, maintaining muscle mass is essential to supporting whole-body protein metabolism, wound healing, physical strength, organ function, skin integrity and immunity. In the elderly, the loss of lean body mass manifests itself as frailty, reduced ability to walk, climb stairs, rise from a chair etc. This loss of independence can not only lead to disability but depression too. As a side note, some fairly recent studies suggest that patients with growth hormone deficiency have a higher risk of developing dental diseases (19). Another dental study utilised GH around implants (20), it recorded that bone repair and collagen 6

Sermorelin is another very fascinating GH peptide and was described by Dr. Richard Walker in issue 2 of the 2012 Aging Matters™ magazine. Sermorelin acts as a secretagogue to encourage the release of GH from the pituitary gland into the blood and it has been shown to be efficacious when taken sublingually, and it is stable at room temperature. Dr. Walker told me that when GHRP2 is taken in combination with sermorelin that the total effects of GH release can be enhanced by up to five-fold! Studies have confirmed this combination synergy, (21, 22, 23, 24, 25, 26). This is obviously a massive improvement and suggests that the combination of these two peptides, (sermorelin taken sublingually PM and GHRP2 taken orally AM) could provide a genuine alternative to injectable GH.

GHRP2-Pro™ IAS’s has now introduced GHRP2 into its peptide range under the name of GHRP2-Pro™. It is an oral liquid, stable at room temperature that can be taken at 4 ml (3/4 of a teaspoon) first thing in the morning; (each serving contains 4 mg of GHRP2). In addition to GHRP2, the GHRP2-Pro™ contains the following supportive agents: • Leucine, (as HMB) is an insulin secretagogue with the capacity to stimulate muscle protein synthesis. • Vitamin D: An essential agent for muscle growth and development. • Mucuna pruriens: A legume extract that mimics L-dopa to increase dopamine levels to enhance GH production.

Conclusion Proper GHRP therapies are perhaps not yet ‘cheap’ options, but at least they are now affordable by many more people. We’ve experienced years of all kinds of touted GH ‘alternatives’ many of which were at best weak performers, or at worst virtual complete wastes of time and money. But now at last, the marketplace has genuine GH alternatives that do not have to be injected to be effective. Thus, there’s mounting evidence that a combination of lifestyle, exercise and anabolic ‘medical food’ supplements such as GHRP2-Pro™ can prevent and reverse sarcopenia in older persons, therefore guarding against this cause of morbidity and mortality.

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Gerovital-H3®; The World’s First Antiaging Supplement is Now 60-Years Old! - By Mircea Dumitru, M.D., Ph.D. Today, Ana Aslan is remembered for her essential contribution to gerontological research as well as for having created a geriatric treatment to influence the aging process, specifically Gerovital-H3®. Ana Aslan was the first person to rule out the fatalistic approach to aging, providing a new method in gerontology by opening the way to the prevention and treatment of old age. I worked with Professor Ana Aslan for 25 years, from 1963, first as a researcher, then as chief physician and afterwards as the Director of the National Institute of Gerontology and Geriatrics in Bucharest, Romania, between 1978 and 1990. In the last 3 years of her life, Aslan chose me as her personal physician and three months before her death she asked me to do some personal things, including to write a book about her life and her work. So I took notes at her bedside as a moral testament. Ana Aslan’s life can be seen in her work. She battled courageously, all for the service of good, to make man’s dream to live with dignity for as long as possible. For 35 years she led the first Institute of Gerontology in the world, she was an Ambassador of Gerontology and a brilliant woman. 8

I asked her many questions on the terrace of her apartment, she talked of the 84 countries she had visited, the people, their cultures, the famous personalities she’d met, and then often, about the history of her only son- Gerovital-H3® - the product that could improve the quality of life. I remember her saying; “to grow old in a beautiful and dignified way is at the same time a science and an art.” When I asked Aslan; “what is aging and old age and how do we fight it?” she answered; “old age is full of suffering and pain and I regard this as a parasite of life which develops slowly and whether you know it or not, it takes hold of us. From the age of 50 onward, I declared war on aging and old age. We have enough possibilities to slow down the aging process and to delay old age onset. We are obliged to guard against it and to explain to healthy or sick patients, what it means to grow old, and what they have to do in order to extend their life in conditions of quality. My treatment and my method is a solution, Gerovital-H3 is not only a treatment, it is hope.”

The biological basis of Gerovital-H3® treatment Ana Aslan stopped using ‘plain’ hydrochloric procaine since

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her research results materialised a different product with a new formula that was named Gerovital-H3®. In the new formula, the addition of benzoic acid to the procaine induced a greater access of the procaine into the hydrophobic cellular compartments and modified the pharmacological action of it. It should be noted that between Gerovital-H3® and hydrochloric procaine there is a difference of pharmacological action. For example, procaine by itself has a stability of 6-months, whereas the Aslan product has a much increased stability of two and half years. Once introduced into the human body, the procaine molecule is hydrolysed into two metabolical fractions; specifically paraaminobenzic acid (PABA) and diethylaminoethanol (DEAE); however the absorption of the two metabolites is better when they result from the in-vivo hydrolysis of GerovitalH3® than when they are administered separately. The procaine from GerovitalH3® has a greater capacity of wadding the medium (pH), due to benzoic acid, reducing the degradation speed of the product. Interestingly, in the case of Gerovital-H3®, the chromatographic techniques showed that there are intact procaine molecules in the blood and heart of experimental animals 6 hours after the product is administered. t is considered that procaine is metabolised differently depending on the pH of the solution. At a pH of 7, the procaine is permeated ‘en mass’ into the blood, but at a pH of 3.3 the procaine is gradually set free from the blood. An acid solution will decrease the sudden release of the substance, a quality that Gerovital-H3® possesses. (1, 2, 3) Therefore, GerovitalH3® acts upon the human body both under the form of an intact molecule and through the hydrolysis products PABA and DEAE, which participate in the regulation of the intermediary metabolism. Gerovital-H3® favors the acetylcholine synthesis and it is a source of folic acid. Research suggests that procaine, by means of PABA, stimulates the intestinal flora and the production of folic acid, vitamin K and tyramine. Pharmacological studies (4) summarise its basic mechanisms as: • Gerovital-H3® competitively and reversibly inhibits monoamine oxidase (MAO). • Gerovital-H3® acts as an anti-depressive through the modification of the MAO level in the brain. • Gerovital-H3® is considered to play a role in maintaining the physiological status of the nervous cell membrane, restoring the equilibrium between the processes of excitation and inhibition at the level of the cortical and subcortical systems. • Gerovital-H3® exerts an important regulatory action upon the nervous vegetative centers. • Further experiments reveal procaine’s anabolic action. • Studies on Infusoria (Colpidium colpoda and Vorticella) show the proliferation of cells (6).

anabolic affects especially improving the quality of the hair (7, 9). Gerovital-H3’s® action upon the lipid mechanism is reflected through several mechanisms: • Gerovital-H3® diminishes the level of plasmatic lipoproteins and lipids. • Gerovital-H3® exerts an effect on the erythrocyte membrane. • Gerovital-H3® has an anti-oxidant mechanism that reduces the oxidative stress exerted on the membrane structure.. It has been shown that Gerovital-H3® action on the lipid metabolism results in positive modifications in improving the serum total of cholesterol, changes to the lipoprotein fractions ratio and also changes to the unsaturated fatty acids content (11).

The international confirmations Mention must be made of the fact that the research concerning Gerovital-H3® therapy has been simulated in more than 500 medical and scientific publications. The experiments that utilized the original Aslan product and method confirm the efficiency and efficacy of Gerovital-H3®. Special interest was generated by the mechanism of GerovitalH3®’s action by several American scientists who presented papers of double-blind placebo controlled trials. Among them was Professor William Zung from Duke University, North Carolina who in his study applied the treatment for 28 days on his patients who were suffering from depression (12). One group of patients aged 60 were submitted before, during and after the treatment to a battery of psychological tests. Professor Zung proved the Gerovital-H3 ® efficiency in the treatment of depression. Furthermore, the American authors, M. Kurland and M. Hayman from Palm Springs, California, presented the double-blind results performed with Gerovital-H3® on 63 patients suffering from depression aged 45 to 80 (33 using Gerovital-H3® and 30 using placebo). Under observation there were several types of depression; manic-depression, reactive depression, organic cerebral depression, chronic reactive depression and alcoholic depression. The results proved that Gerovital-H3® efficiency in all the tests applied, the differences between the two groups showed a great statistical significance. Recognition has come from the world-wide known gerontologist, Alex Comfort of England, who in an article published in the magazine ‘Mechanism of Ageing and Development’, made positive remarks upon Gerovital-H3® and Aslan’s method and on the occasion of the international meeting ‘Medizinischewoche’ in Baden Baden, Germany, whilst concluding the Gerontology and Geriatrics section, Professor Paul Luth said; “The Aslan treatment method represent a most efficient therapeutic procedure in geriatrics.” (15)

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Aslan’s method of prophylactic and curative treatment with Gerovital-H3® Ana Aslan declared of Gerovital-H3®; “After one injection in the femoral artery given to a patient with embolism at the level of the inferior extremity, I noticed the almost instantaneous disappearance of pain. Then, for the first time, I had the idea of applying the same method in certain diseases with acute pain, which produce immobilization and thus long-lasting work incapacity.” Like other great discoveries, the clinical observation facts did not fail Aslan, as they represented the beginning of a period of original and fundamental studies which contributed to the prophylaxis and treatment of aging and chronic disease. Thus, in that period, another clinical observation was pointed out by the patients who stated that after the injections, (given into the artery of the extremities) pain was relieved in all the body. Injectable Gerovital-H3® was first experimented with at the Institute of Gerontology and Geriatrics in Bucharest in 1953 and then in 1957 Aslan started comparative investigations to establish the effectiveness of the oral treatment. It was found that in order to achieve the same results like in the parental treatment, the oral dose had to be doubled

Indications for Gerovital-H3® Gerovital-H3® is indicated for people older than 40 years in order to retard the aging process and as a preventative and curative treatment for chronic degenerative diseases. GerovitalH3® has been shown to be efficacious in all the following: • Moderate and light depressive states. • In troubles concerning attention, concentration and cognitive processes. • Chronic fatigue syndrome. • Sleep disorders. • Tegument dystrophies, trophic ulcers, atonic wounds. • Osteoarthritis, degenerating rheumatism, osteoporosis and during fracture consolidation periods. • Sexual management and improving sex drive. • Gerovital-H3® is an active anti-aterogenous factor and recommended in cerebral and peripheral arthrosclerosis. • Parkinson’s disease and Parkinsonian syndromes. • Gerovital-H3® ameliorates the hair quality, its repigmentation and reduces alopecia (hair loss) and head skin seborrhoea (dandruff). • Due to the inhibition on the generation of the superoxide radical, Gerovital-H3® is also a powerful antioxidant.

Outcome of Gerovital-H3 ® treatment 10

Aslan’s treatment produces a general transformation of the organism manifested as follows: • Desires to be active, have better memory, enhanced concentration and improved optimism. • Greater affective tone and psychic and vegetative balance. • Increased self-caring abilities and exercise capacity. • More ability to cope with the environment and increased resistance to infections. • Better balanced endocrine functions with estrogens reappearance and androgen reactivation. • Improved visual, audio and smell acuity. • Diminished extrapyramidal rigidity, improved gait and increased mobility. • Better skin, nails and mucous. • Hair growth stimulation with a tendency to repigmentate the hair and a more trophic aspect. • Better blood vessel reactivity. • Alleviation of the clinical symptoms of chronic diseases such as rheumatism, atherosclerosis, bronchial asthma, psoriasis, vitiligo and varicose ulcers. • Improves the quality of life retarding the rhythm of aging and preventing the chronic diseases. • Improved sex drive.

Administering method for Gerovital-H3® The long term treatment with Gerovital-H3 ® has been extensively established by Aslan. In the beginning, Gerovital-H3 ® was administered only as injections. The tolerance has always been tested before starting the treatment; one subcutaneous injection of 1 ml on the first day, followed by an intramuscular injection of 2 ml the next day.


If no local or general reactions occur, proper treatment can be started. In the experience of more than 300,000 patients that completed this treatment in Romania, intolerance only occurred in 1 in 7000 cases.

Preventative treatment Treatment of chronic diseases and aging consists of 4 courses of 12 injections and 4 courses of 24 pills, i.e., one course of 12 injections over 4 weeks (i.e., 3 injections per week), a 4-week break then one course of 24 pills over 12 days (one pill twice daily between meals), a 2-week break and then the cycle is resumed. Starting from the age of 40 years, the prophylactic treatment with pills only is recommended in a series of 25 tablets during the first 12 days, with an interval of 2 months; 1st day, 1 tablet/ day, 2-hours after breakfast, increasing to the 12th day when 2 tablets per day are taken, (again 2-hours after meals, for example one at 10 AM and another at 4 PM). There should a series of 5 treatment courses in the year, which should be increased to 6 per year for persons over the age of 65.

Curative treatment Chronic diseases require a 6 course of 12 injections, and 5 courses of 24 pills, yearly, i.e., one course of 12 injections over 4 weeks, a 2-week break, one course of 24 pills over 12 days (one pill twice daily between the meals); 2 week break. The cycle is then resumed. Depending upon the outcomes the physician and patients can either shorten or extend the breaks. The first and second course of injections can be administered daily in order to study the individual reactivity. Gerovital-H3® treatment can be individualised according to the disease/ diseases accompanying the aging and the patient’s biological age.

Contraindications Gerovital-H3® should be avoided by anyone suffering or utilising the following; • Allergy or sensitivity to Gerovital-H3® (or Novocaine). • Gerovital-H3® cannot be used together with eserine or prostigmine. • Gerovital-H3® cannot be used at the same time as sulphamides. • Gerovital-H3® should not be used with an antibacterial treatment.

Side effects Gerovital-H3® side effects are uncommon. With injections minor side effects consist of a heating sensation and metallic taste; these effects disappear during the treatment. Other side effects are related to the skin; macular eruption, rash and itch-

ing which determine the interruption of the treatment and the remake of the tolerance test (1 ml injected id.) after the eruption has disappeared. In spite of its monoamine oxidase (MAO) inhibitor character, Gerovital-H3® does not interfere, as the conventional MAO inhibitors do, with the tyramine from food (commonly called the cheese affect), which means there is no known incompatibility with Gerovital-H3® and food.

References 1. Cohen S., Ditman K.S. Effects of Gerovital-H3® on Elderly Depressive Patients. Int. Symposium of Gerontology, Bucharest, 1972. 2. Teitel A., Gane P., Stroescu V., Steflea D., About the Mechanisms of Procaine. Studies of Fisiology, Bucharest, 1962, 4, 351-360. 3. Gordon P., Fudema A., Abrams A., Effects of Romanian and American Procaine Preparations on Certain Physiological Aspects of Aging. Gerontologist II, 1962, p.9, Gerontologist, 1965, 20, 2, p114-150. 4. Ana Aslan; Gerovital-H3 ® Therapy in the Prophylaxis of Ageing. Rom. J. Geront. Geriatrics. Bucharest, 1980, 1,1 p5-15. 5. Yau M.T. Gerovital-H3 ®, Monoamine oxidase and Brain Monoamines. Symposium on Theoretic Aspects of Aging, 1974, Miami, Florida. 6. Parhon C.I., Ana Aslan, L’action de la Vitamine H1 et H2 sur la proliferation de la cellule animale. Bull. Acad. Rom. Bucharest, 1957, 9, 1, 137. 7. Berger P; Innocuite du traitment chronique a la procaine chez le rat en croissance. C.R. So. Biol. 1960, 154,959. 8. Verzar F. Note on the influence of procaine, PABA and DEAE on the aging of rats. Basel, 1959, Gerontology 3, 6, 350-355. 9. Ana Aslan et col. Long term treatment with Gerovital-H3® in Albino rats. J. Gerontology, 1965, 20, 1. 10. Ana Aslan, G. Enachescu. Researches on the Antithrombophilic activity of Gerovital-H3® treatment. Rom. J. Geront. Geriatrics, 180, 1, 2, 195-246. 11. Russu C et col. Antioxidant and lipid lowering effect of original procaine based product Gerovital-H3®. Book of abstracts. The 16th Congress of the International Association of Gerontology, p217. 12. Zung W.W.K., Wang H.S. Clinical trials of Gerovital-H3® in the treatment of depression in the elderly. 10th Int. Congress of Gerontology, 1975, Jerusalem. 13. McFarlane MD Gerovital-H3® therapy; Mechanism of inhibition of monoamine oxidase. J. of American Geriatrics Society., 1974, XXII/8, p365-371. 14. Robinson D.S. et al; Aging, monoamine and monoamine oxidase levels, 1972, Lancet, 1, 0290. 15. Luth P. Aslan therapie mit Gerovital-H3 ®. Zeitschrift fur Algemenmedizin, 1984, 60, 27, p1162-1164.

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The Hair Growth Factors By Leslie J. Farer

The goal of an antiaging regimen is to increase life-span by promoting a youthful physiology on the inside, but for most, a vibrant outward appearance is equally important. Avoiding excess weight, keeping in shape, and discouraging wrinkles by maintaining skin quality are all essential for a years-younger exterior, and, as we will discuss in this article, so is reducing or eliminating hair loss. Hair ─ its style, color, condition, and amount ─ is a central component to one’s overall appearance and even one’s self-esteem. Thinning hair and a balding head do not have to be inevitable consequences of aging! Shedding up to a few dozen hairs a day is normal, but excessive loss, known as alopecia, is a cause for concern. There are many types of hair loss, the most common of which is androgenetic alopecia, which exhibits as male-pattern baldness in men (a receding hairline at the temples and balding at the top of the head) and female-pattern hair loss in women (a general diffuse thinning of the hair). As the name implies, androgenetic alopecia is androgen-dependent and heriditary, resulting in the atrophy or miniaturization of predisposed hair follicles and progressive decline in hair density. (1, 2) So let’s examine the micro-anatomy of the hair follicle and its key component, the dermal papilla.

Dermal papilla controls hair growth by producing cytokines in response to androgens The dermis, the second layer of the skin just under the outer layer, the epidermis, contains tens of thousands of tiny and complex structures, the hair follicles, which enclose the hair

root. At the base of each follicle is a bulb-like projection, the dermal papilla, surrounded by the hair matrix, a group of cells which divide to form the major structures of the hair fiber and root. The dermal papilla regulates the growth of hair, which in humans occurs in unsynchronized cycles, with each hair entering a phase of the cycle at a different time. Anagen is the stage of active hair growth; catagen is a short resting phase until telogen, when the hair falls out. Under normal circumstances, the cycle then repeats. During the anagen growth phase, stem cells migrate to the hair matrix and divide and differentiate in a process controlled by numerous cytokines produced by the dermal papillae. (3) (Cytokines are regulatory proteins involved in intercellular communication.) The synthesis and release of these cytokines is influenced by androgens which bind to receptors of the dermal papillae. (1, 3) Most released cytokines stimulate cell proliferation and hair growth; however, in response to particular androgens, and in certain areas, such as the sides and top of the head, some cytokines induce follicle atrophy, leading to hair thinning and eventual loss. (3) Of all androgens, the one that most negatively influences dermal papilla cells to produce follicle-shrinking cytokines is 5-α-dihydrotestosterone (DHT), which is synthesized from testosterone by the enzyme 5-α-reductase. (1, 3) The FDA-approved drug finasteride, (brand names Propecia® or Proscar®) inhibits a form of this enzyme, type 2 5-α-reductase, and prevents the conversion of testosterone to DHT. Daily oral administration of finasteride has been shown to be effective in the prevention and treatment of hair loss in men. (1, 3-5)

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down-regulating apoptosis. (19 Besides cytokines, growth factors also among bioactive Providing for the health of the molecules involved in hair cycle new hair regulation Other ingredients, while not directly influencing hair growth Three polypeptide growth factors are crucial to the regulation of the hair cycle: these are insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), and basic fibroblast growth factor (bFGF). Both bFGF and IGF-1 potentiate the growth of hair follicles. (3, 6-10) In addition, IGF-1 prevents cell death (apoptosis) in many cell types, which may be important in promoting the anagen growth phase and delaying the catagen (apoptosisdriven) phase. (6) In a few fascinating studies, hair growth in humans with alopecia was promoted by inducing IGF-1 production. (7, 11) Interestingly, another way DHT impacts hair loss besides stimulating the production of alopeciainducing cytokines is by inhibiting IGF-1 production at the dermal papillae. In an animal study, mice administered DHT exhibited reduced expression of IGF-1, which resulted in a lower number of proliferating cells in hair follicles and decreased hair growth. (12) A third growth factor, VEGF, is essential for establishing a highly developed blood vessel network around the hair follicle dermal papillae during the anagen growth phase. Research has demonstrated that improved follicle vascularization, or formation of blood vessels, induces hair growth by increasing the size of follicles and hair shafts. (13-15) In fact, stimulation of VEGF expression to promote follicle vascularization is a likely mechanism of action of the hair-growth drug minoxidil. (15)

Additional novel ingredients: a potassium channel activator and an energy-enhancing amino acid Another truly innovative approach to youthful, radiant sAdditional agents such as niacin and L-carnitine stimulate potassium ion channels within the dermal papillae of hair follicles to induce hair growth. Potassium channels are poreforming proteins that control the flow of potassium ions across the cell membrane and are essential to the follicle’s function. Niacin (nicotinic acid) bears a structural resemblance to minoxidil, and another mechanism by which minoxidil positively impacts follicles besides stimulating VEGF production, as we have just seen, is through activation of their potassium channels. (2, 15-18) The amino acid L-carnitine transports long-chain fatty acids across the mitochondrial membrane where they undergo oxidation to produce energy. Researchers have shown that L-carnitine promotes hair growth in humans by increasing energy production in proliferating anagen hair matrix cells and 14

can insure the condition and quality of the follicle-containing scalp, promoting the health of the new hair are: • Hyaluronic acid (HA): A carbohydrate polysaccharide that occurs naturally throughout the body, predominantly in skin, but also in joints, tendons, connective tissue, and eyes, among other locations. HA has the remarkable ability to bind large quantities of water, forming a thick, gelatinous substance that lubricates movable parts of the body, while also keeping skin and follicle-containing dermal layer of the scalp hydrated. A nourished, moisturized scalp encourages the production of healthy, lustrous hair.


• Dexpanthenol: The alcohol analog of the B vitamin pantothenic acid, is important in stimulating skin regeneration. When used topically, dexpanthenol has been shown to penetrate the skin, reduce water loss, moisturize, and maintain skin softness and elasticity. (20) Like HA, dexpanthenol is a common ingredient in cosmetics and moisturizers, and also promotes the health and condition of the hair.

Conclusion The processes involved in hair growth ─ and hair loss ─ are anatomically and physiologically complex, involving a long chain of factors and control mechanisms. Thankfully, on-going research has revealed opportunities to intervene in the biological chain of events that lead to alopecia as well as positively activate factors that promote a healthy head of hair. Hair-Pro™ contains IGF-1, VEGF, niacin, L-carnitine, HA, dexpantherol and finasteride; thus it acts on all fronts: it is formulated to combat hair loss by blocking the lethal effects of DHT on follicles, while at the same time encouraging new growth through the action of three biological growth factors, a potassium ion channel activator, and a cellular energy booster ─ all this while also fostering the health of the new hair that does grow. Whilst there are hundreds of single-ingredient hair-growth products and drugs on the market that target one mechanism of hair loss, IAS’s multi-acting Hair-Pro™ is the only one to combine all of this factors, making it a truly breakthrough product!

References 1. Trüeb RM. Pharmacologic interventions in aging hair. Clin Interv Aging. 2006;1(2):121-9. 2. Otomo S. Hair growth effect of minoxidil. Nihon Yakurigaku Zasshi. 2002 Mar;119(3):167-74. 3. Jankovic SM, Jankovic SV. The control of hair growth. Dermatol Online J. 1998 Oct;4(1):2. 4. Rossi A, Cantisani C, Scarnò M, Trucchia A, Fortuna MC, Calvieri S. 5. Dermatol Ther. Finasteride, 1 mg daily administration on male androgenetic alopecia in different age groups: 10-year follow-up. 2011 Jul;24(4):455-61. 6. Hajheydari Z, Akbari J, Saeedi M, Shokoohi L. Comparing the therapeutic effects of finasteride gel and tablet in treatment of the androgenetic alopecia. Indian J Dermatol Venereol Leprol. 2009 Jan-Feb;75(1):47-51. 7. Su HY, Hickford JG, Bickerstaffe R, Palmer BR. Insulinlike growth factor 1 and hair growth. Dermatol Online J. 1999 Nov;5(2):1. 8. Harada N, Okajima K, Arai M, Kurihara H, Nakagata N. Administration of capsaicin and isoflavone promotes hair growth by increasing insulin-like growth factor-I production in mice and in humans with alopecia. Growth Horm IGF Res. 2007 Oct;17(5):408-15. Epub 2007 Jun 13.

9. Weger N, Schlake T. Igf-I signalling controls the hair growth cycle and the differentiation of hair shafts. J Invest Dermatol. 2005 Nov;125(5):873-82. 10. Ozeki M, Tabata Y. Promoted growth of murine hair follicles through controlled release of basic fibroblast growth factor. Tissue Eng. 2002 Jul;8(3):359-66. 11. du Cros DL. Fibroblast growth factor and epidermal growth factor in hair development. J Invest Dermatol. 1993 Jul;101(1 Suppl):106S-113S. 12. Harada N, Okajima K, Narimatsu N, Kurihara H, Nakagata N. Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans. Growth Horm IGF Res. 2008 Aug;18(4):335-44. Epub 2008 Mar 5. 13. Zhao J, Harada N, Okajima K. Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae. Growth Horm IGF Res. 2011 Oct;21(5):260-7. Epub 2011 Aug 11. 14. Yano K, Brown LF, Detmar M. Control of hair growth and follicle size by VEGF-mediated angiogenesis. J Clin Invest. 2001 Feb;107(4):409-17. 15. Kozlowska U, Blume-Peytavi U, Kodelja V, et al. Expression of vascular endothelial growth factor (VEGF) in various compartments of the human hair follicle. Arch Dermatol Res. 1998 Dec;290(12):661-8. 16. Lachgar S, Charveron M, Gall Y, Bonafe JL. Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br J Dermatol. 1998 Mar;138(3):407-11. 17. Shorter K, Farjo NP, Picksley SM, Randall VA. Human hair follicles contain two forms of ATP-sensitive potassium channels, only one of which is sensitive to minoxidil. FASEB J. 2008 Jun;22(6):1725-36. Epub 2008 Feb 7. 18. Davies GC, Thornton MJ, Jenner TJ, et al. Novel and established potassium channel openers stimulate hair growth in vitro: implications for their modes of action in hair follicles. J Invest Dermatol. 2005 Apr;124(4):686-94. 19. Hamaoka H, Minakuchi K, Miyoshi H, Arase S, Chen CH, Nakaya Y. 20. Effect of K+ channel openers on K+ channel in cultured human dermal papilla cells. J Med Invest. 1997 Aug;44(12):73-7. 21. Foitzik K, Hoting E, Förster T, Pertile P, Paus R. L-carnitine-L-tartrate promotes human hair growth in vitro. Exp Dermatol. 2007 Nov;16(11):936-45. 22. Ebner F, Heller A, Rippke F, Tausch I. Topical use of dexpanthenol in skin disorders. Am J Clin Dermatol. 2002;3(6):427-33.

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Dr Ward Dean answers your questions We are delighted that Ward Dean, M.D., one of the world’s foremost antiaging physicians, has agreed to answer our readers’ questions. Full details about Dr. Dean can be seen at his website: www.warddeanmd.com

Dear Dr Dean… Q. I am very interested in using the Can-C™ eye-drops to help fight my cataract- but how soon might I see positive results and what may I do in addition to speed things along? - R.M.F., Scotland A: In my experience, 3-6 months is the minimum time to see improvement with Can-C™, although I have known people who have persisted, and did not see improvement until over one year had elapsed. Of course, the time required depends on the person’s diligence with the drops, and the degree of progression of the cataract at the time the treatment, (2-drops twice a day) was begun. The formulators of Can-C™ eyedrops also designed Can-C Plus capsules, as an oral adjunct to the eye-drops. Note: Dr. Babizhayev, the principal Can-C™ researcher, doesn’t recommend lutein (found in many ‘eye’ formulas), as lutein competes with same receptors as N-acetyl carnosine, and could down-regulate efficacy of the drops. An alternative to Can-C™ capsules, would be to take L-carnosine itself, one of the principal (and I believe, most active) ingredients in Can-C™ Plus capsules. Additionally, you might consider the AGE-breaking aminoguanidine. Several Japanese research teams have demonstrated the ability of aminoguanidine to inhibit or completely prevent the development of cataracts in two diabetes-prone rat strains. The first team used the Shumiya cataract rat (SCR). SCR is a hereditary cataract model in which lens opacity appears spontaneously in the nuclear and perinuclear portions at 11-12 weeks of age. The researchers found that oral administration of aminoguanidine (AG)

strongly inhibited the development of lens opacification in SCR rats. In another very recent study, the researchers used another strain, Spontaneously Diabetic Torii (SDT) rats. SDT rats have marked hyperglycemia and severe ocular complications. They evaluated the effect of the anti-AGE agent, aminoguanidine, on the development of diabetic retinopathy (DR) and cataract. Five SDT rats were treated with aminoguanidine (0.5 g/L in drinking water). During the duration of the study, ALL of the control rats developed cataracts, whereas NONE of the aminoguanidine-treated rats developed cataracts. These results were dramatically illustrated in the accompanying photographs (Figure 1). The researchers concluded that aminoguanidine had a strong inhibitory effect on diabetic ocular complications in SDT rats. Although I have unfortunately not found any human studies to corroborate these findings in rats, aminoguanidine has been shown to be safe and effective in humans for a number of conditions, and I would expect it to have the same cataractinhibiting effect in humans as it has in rats. 1. Mitsushi Inomata, Masami Hayashi, Seigo Shumiya, Seiichi Kawashima and Yoshimasa Ito. Aminoguanidine-Treatment Results in the Inhibition of Lens Opacification and CalpainMediated Proteolysis in Shumiya Cataract Rats (SCR). The Journal of Biochemistry, 2000 Volume 128, Issue 5, Pp. 771-776. 2. Fumihiko Toyoda, Akihiro Kakehashi, Ayumi Ota, Nozomi Kinoshita, Chiho Kambara, Hiroko Yamagami, Hiroyuki Tamemoto, Hiroto Ueba, Prevention of Proliferative Diabetic Retinopathy and Cataract in SDT Rats with Aminoguanidine, an Anti-Advanced Glycation End Product

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Agent. The Open Diabetes Journal, 2011, 4, 108-113

was awarded in 1998 for its discovery. Unfortunately as we age, we lose our ability to produce NO. This puts us at risk for a host of conditions, including hypertension, atherosclerosis, myocardial infarction (i.e., heart attacks), stroke, Alzheimer’s disease, and erectile dysfunction. One way to increase NO is to consume the nitric oxideproducing amino acid, arginine. The effect of oral arginine intake to improve erectile response was first investigated in animal models. Older rats supplemented with arginine resulted in increased nitric oxide synthase activity and increased nitric oxide levels, which caused improved erectile response. The authors of the study suggested that dietary supplementation with arginine might lead to improved sexual performance in humans, as well. The first evidence that oral supplementation with arginine might lead to improvement in human sexual function came from a short-term study in 1994. The study showed a positive correlation between arginine supplementation and sexual performance and satisfaction.

Figure 1, the Effect of aminoguanidine on diabetic cataract and retinopathy. The top row shows the slit-lamp findings in the lens. The untreated control rat has mature diabetic cataracts, whereas the aminoguanidine-treated SDT rat has minimal lens opacity. The bottom row shows the fluorescein angiomicroscopy findings. The untreated control rat has extensive fluorescein leakage and narrowing of the capillaries around the optic disc. The aminoguanidine-treated SDT rat has no abnormalities.

Q. I am a 48 year old male and over the last couple of years have noticed that my erections are becoming weaker, to the point where, although not diagnosed, I am sure that I have erectile dysfunction. I don’t really want to become reliant on taking a Viagra® pill every time my wife and I have sex, what can you recommend Dr. Dean and what may address the cause of this problem rather than just the symptoms? - S.S.K., Canada A: First, I suggest that you ask your physician to check your testosterone levels. If they are in the low or low-normal range, you might ask him to prescribe testosterone. I prefer injectable testosterone (cypionate or enanthate) usually 200 mg injected intramuscularly every 2-3 weeks. Alternatively, the topical creams or gels may also help, although I believe topical testosterone is not as effective as the injectable route. That may solve your problem.

These intriguing findings were supported by a more recent, larger study conducted at the Department of Urology and Nephrology at Tel Aviv University in Israel. Fifty men with confirmed erectile dysfunction were administered either a placebo or 5 g/day arginine for six weeks. Thirty-one percent of the subjects receiving arginine reported improvement and satisfaction in their sexual performance. In the placebo group, only 12% of the men noted improvement in sexual function. Importantly, at the 5 gram daily dose, no significant side effects occurred in any of the patients throughout the entire duration of the study. The percentage of patients reporting improved performance (31%) may not sound like an impressive number, but keep in mind that up to 50% of Viagra® users report no benefit from taking this prescription medication. As a source of arginine, IAS offers Nitric-Pro™ powder, which contains a hefty 3500 mg of L-arginine plus magnesium (to help relax the smooth muscle layer of the endothelium), per serving. Unfortunately, the intestinal enzyme, arginase reduces the effectiveness of the conversion of oral arginine to NO by metabolizing arginine, reducing the amount that is available for conversion to NO. Citrulline may offer a solution. Citrulline is a semi-essential amino acid that is not found in the diet- it is synthesized in the body via a mechanism called the urea cycle. In this metabolic pathway, arginine is catalyzed by the enzyme arginase to urea and ornithine. Ornithine, in turn, is

Another approach, in this regard, is IAS’s new Andro-Pro™. It is designed to naturally raise testosterone levels, although I have not had any clinical experience with it yet. However, there are several nutritional alternatives to Viagra® and the other phosphodiesterase (PDE-5)-inhibiting drugs like Cialis® and Levitra®, all of which are designed to increase the production of endothelium-derived nitric oxide (NO), one of the most important signaling molecules in our bodies. Nitric oxide was designated ‘Molecule of the Year’ by the journal, Science, in 1992, and a Nobel Prize in Physiology or Medicine 18

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converted to citrulline, which is converted to argininosuccinate, which is converted back to arginine, completing the cycle. It has recently been shown that oral citrulline supplementation increases the plasma arginine concentration and augments NOdependent signaling in a dose-dependent manner. This provides the rationale for using oral citrulline supplementation as a donor for the arginine/NO pathway in those with ED. An article in Urology described a pilot trial aimed to determine whether oral citrulline supplementation could improve erection hardness in patients with mild ED. In the Urology study, 24 men (mean age of 56.5 ± 9.8 years) with mild ED (erection hardness score [EHS] of 3) received a placebo for 1 month. They were then given citrulline, 1.5 g/day split into two doses, for another month. At the end of the study, the erection hardness score, number of intercourses per month, treatment satisfaction, and adverse events were recorded.

In the first group (n = 20), all patients regained spontaneous and sufficient erections after six months of oral GBE treatment. Arterial flow rates were actually improved after three months and continued to improve at six months. Rigidities at the penile tip and base were significantly improved after six months and remained constant during the nine month duration of the study. In the second group (n = 30) (this was the group that did not respond to high-dose papaverine injections—i.e., a very severe state of ED), improved arterial penile flow rates and rigidities were noted at six and nine months. Nineteen patients, responded to intracavernous PGE1 following GBE treatment. Of these 19 patients, 9 required a minimal dose of 5 mcg PGE1, while the other 11 required a maximal dose of 20 mcg. The remaining 11 patients remained impotent. Thus, it appears that Ginkgo biloba extract at a dose of 240 mg per day may also greatly assist those with ED.

The improvement in the EHS from 3 (mild ED) to 4 (normal erectile function) occurred in 2 (8.3%) of the 24 men when taking placebo during the first half of the study. But when the subjects were switched to citrulline, 12 (50%) of the 24 men reported achieving an EHS of 4. An EHS of 3 is considered “hard enough for penetration but not completely hard,” while an EHS 4 is “completely hard and fully rigid.” citrulline increased hardness by 50%. At the same time, the mean number of intercourses per month increased from 1.37 at baseline to 1.53 at the end of the placebo phase (about 12% greater frequency) and 2.3 at the end of the treatment phase (about a 68% increase) for citrulline. Citrulline increased successful intercourse connects by 56% more than placebo, and all patients reporting an EHS improvement from 3 to 4 reported being very satisfied.

In summary, I recommend evaluation of testosterone levels, and replacement, if appropriate, or using Andro-Pro™, arginine (3-5 grams per day) or the arginine-containing NitricPro™, citrulline (1.5 grams per day), Neo40® (1 tab twice daily), and Ginkgo biloba (240 mg per day). I don’t recommend starting everything at one time—rather, begin with one nutrient at a time, and add other nutrients in sequence so you can tell what is (and is not) working.

Perhaps the most effective way to increase nitric oxide has recently become available. It is a patent-pending combination of natural products, developed at the University of Texas Health Science Center, called Neo40®. Neo40® is primarily a combination of nitrate-rich beet root, and nitrate reductase activity-enhancing Hawthorn Berry extract, plus a relatively small amount of citrulline. Preliminary clinical studies at the Houston Institute for Clinical Research indicate that Neo40® has demonstrated clinically relevant increases in NO and serum nitrate concentration, improvement in triglyceride levels, and normalization of blood pressure in hypertensive patients. Anecdotal reports from my patients who have used Neo40® also include rapid relief from angina attacks, and Viagra-like enhancement of sexual performance. Another approach to improving erectile dysfunction is the timehonored multi-purpose herb, Ginkgo biloba extract (GBE). In a 1991 study, fifty patients with proven arterial erectile impotence were treated with 240 mg of GBE daily for nine months. The patients were divided into two groups. The first group had achieved sufficient erections with intracavernous papaverine injections before beginning treatment with GBE. The second group had not achieved sufficient erections with high-dose papaverine injections.

1. 1. Moody JA, Vernet D, Laidlaw S, Rajfer J, GonzalezCadavid NF. Effects of long-term oral administration of L-arginine on the rat erectile response. J Urol 1997;158: 942-¬7. 2. 2. Zorgniotti AW, Lizza EF. Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction. Intl J Impot Res 1994;6:33-¬5. 3. 3. Chen J, Wollman Y, Chernichovsky T, Iaina A, Sofer M, Matzkin H. Effect of oral administration of high-dose nitric oxide donor L-arginine in men with organic erectile dysfunction: results of a double blind, randomized, placebocontrolled study. BJU Int 1999;83: 269¬-73. 4. 4. Cormio L, De Siati M, Lorusso F, Selvaggio O, Mirabella L, Sanguedolce F, Carrieri G. Oral citrulline supplementation improves erection hardness in men with mild erectile dysfunction. Urology 2011 Jan;77(1):119-22. 5. 5. Janet Zand, Frank Lanza, Harsha K. Garg, and Nathan S. Bryan. All-natural nitrite and nitrate containing dietary supplement promotes nitric oxide production and reduces triglycerides in humans. Nutrition Research, 31 (2011) 262269. 6. 6. M. Sohn M and R. Sikora. Ginkgo biloba extract in the therapy of erectile dysfunction. J Sex Educ Ther (1991) 17: 53-61. Q. My blood pressure seems to be rising, it used to be often 120/80, now it appears to be often around 140/90 - furthermore my resting heart rate can sometimes be around 90 beats per minute. I avoid caffeine and whilst I am overweight I am not obese and do mild exercise

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regularly. I am a 55 year old man. - F.M., Missouri A: Although there are several nutrients that may lower blood pressure, the combination of high blood pressure with increased heart rate is best treated with a beta blocking antihypertensive medication. Propranolol (Inderal®) is good, although cardio-selective beta blockers like Atenolol®, Labetalol®, Carvedolol® or Metoprolol® are also excellent. These medications act to slow the heart rate, (I prefer a resting rate of 65-75 BPM), while simultaneously normalizing blood pressure. Start with low doses, and gradually increase the dose until the target heart rate is obtained. Naturally, please discuss these recommendations with your physician. I recommend first normalizing your pressure (and heart rate) with one of these medications. You may also add a combination of potassium and magnesium for longer term use, which may enable you to wean yourself from the medication. I often prescribe magnesium-potassium aspartate as a source for these two minerals. The dose can be gradually titrated up to bowel tolerance (magnesium in high enough doses will cause GI distress and diarrhea)—but before that point is reached, blood pressure will usually return to normal. In addition to monitoring your blood pressure, another useful parameter to follow is your Arterial Stiffness Index (ASI). ASI is one of the best biomarkers of biological aging, as documented in my book, Biological Aging Measurement— Clinical Applications. At the time the book was published (1988), only the most sophisticated cardiovascular testing labs had the expensive equipment required to conduct this test. In recent years, the folks at IAS discovered a compact, computerized unit that was affordable for Doctors’ offices (BioClip™, $799.99), and have now added a personal unit suitable for home use (Bio-Cuff™-$124.99). Q. As I have gotten older I find that my sleep quality has appeared to have worsened. Now as a 70-year old woman I find that it’s not just the quality of the sleep but the time also. I am now at the point where I seem to be sleeping on average about 4 hours a night. What procedures can I follow to improve this and are there any sleeping drugs you recommend? - G.M., Australia A: In Aging Matters™, Issue #1, 2013, I answered a similar question, and suggested the anti-seizure drug, gabapentin (Neurontin®), as a powerful sleep aid. Gabapentin is an analog of the ‘notorious’ GHB. GHB is actually the safest, most nontoxic, non-habit forming sleep inducing agent there is. It is a natural substance, existing in every cell in our bodies in small amounts. When taken in adequate doses, it induces sound, restful sleep—enhancing all four phases of sleep—and is metabolized into harmless carbon dioxide and water. My experience with gabapentin as a sleep inducing agent is excellent. Although gabapentin doesn’t work for everyone, most of my patients gratifyingly report that it causes sound, restful sleep, without frequent early-morning awakenings. When taken in an appropriate dose, at the proper time, there 20

is little to no ‘hangover’ effect. If you experience a hangover, take it an hour or so earlier, or reduce the dosage. Dosages of gabapentin must be individualized. Some very sensitive people find as little as 300 mg to be adequate. Usually, however, 600800 mgs are effective and some highly resistant patients require 900-1200 mg. It is a very safe, non-habit forming medication. IAS now stocks gabapentin. Q. I am a 40-year old woman, in otherwise good health and fit. But I have recurring skin problems, specifically acne and boils which not only appear on my face, but other parts of my body such as my back. Obviously this is not a pleasant experience for me, I have tried using fiber and vitamin C to help detox myself with some limited success, but I would welcome your advice. - N.M., England A: Of course, I’m at a disadvantage in not being able to ‘eyeball’ your lesions. Skin lesions as you describe could be due to Rosacea, acne, or even by infectious microbes like staphylococcal bacteria. With that caveat, here are some general suggestions. Vitamin D is essential for healthy skin, and a healthy immune system. Most of my patients are deficient in this essential vitamin. I like to see levels in the range of 60-70 ng/ml. To reach these levels usually requires supplementation of 5,00010,000 IU per day. IAS has a very potent form of Vitamin D, D3-Pro, in a dose of 50,000 IU, these capsules should be taken once per week. [Ed- IAS now also stocks D3-5000 which are 5000 IU capsules). Tetracycline or doxycycline may help. The usual dose of doxycycline is 100 mg twice per day. You may have to continue to take smaller ‘suppressive’ doses on a chronic basis, if you find that this will control your outbreaks. Another suggestion is to purchase a bottle of ‘hand sanitizer’—basically an ethyl alcohol gel, and apply it topically to the skin several times daily. This will kill bacteria on the skin, and should help to ‘dry up’ your lesions. If you have acne, you may apply Retin-A® topically, as well—although if you are truly having ‘boils’ (i.e., abscesses), Retin-A® will probably not be effective. Finally, have you had your hormone levels tested? Excess testosterone (as can occur if you are taking DHEA—women very efficiently convert DHEA to testosterone) is known to cause acne in women. If you are taking DHEA, I’d suggest reducing your dose.

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1st Line™ (thiocyanate) 1st Line is an exciting new and all natural weapon in the fight against various types of infections including viruses. 1st Line contains a patented formula that when made up with water becomes a drink that contains thiocyanate ions.

Adrafinil (Olmifon®)

Thiocyanate ions (also known as oxythiocynate) are the same molecules made in body’s airways and passages, for example they can be found in tears, saliva and milk and they literally form the body’s first line of defence against all types of bacteria, yeasts, fungi, flukes, germs and even viruses, helping to destroy them on contact. Consuming 1st Line helps to flood the bloodstream with thiocyanates, but unlike antibiotics 1st Line does not attack self-molecules, in other words beneficial floras are not disturbed. Clinical trials have exposed that 1st Line can help quickly to combat various infections relating to helicobacter, pneumonia, soft tissue infections, upper respiratory tract infections and bronchial infections. Other doctors have reported to us that their patients with various viral infections are asymptomatic, even months later after using a few doses of 1st Line. “...thiocyanate ions are not toxic to human cells... and have little if any effect on probiotic species, making them a near perfect antibiotic system.” Professor Paul Clayton

ACF228™ Dr. Lippman was nominated for the Nobel Prize in Medicine for his work to measure free radical production within the body and as everyone knows free radicals are unstable molecules that cause a lot of damage associated with aging and degeneration. The result of Dr. Lippman’s work is the unique patented and exclusive to IAS- ACF228 (this stands for ‘antiaging complete formula’ version 228). The capsules are designed to neutralise damaging free radical production and help to reduce other age related

Adrafinil works like modafinil- it resensitizes alpha-1 receptors in the brain to be more sensitive to noradrenaline. This heightens awareness and concentration to prevent narcolepsy (sleeping in the daytime). The results can be quite remarkable, leading to heightened states of awareness and attention, whilst at the same time not affecting sleep patterns nor causing ‘highs and lows’ that were associated with the earlier form of stimulants. Adrafinil is not recommended for continuous use past 3-months unless liver enzymes are being monitored.

Aminoguanidine (pimagedine) Aminoguanidine is internationally recognised as the most potent AGE inhibitor currently available. The abbreviation AGE means ‘advanced glycated end products.’ AGEs are cross linked proteins that do not work efficiently/ correctly and are seen in a number of disorders including diabetes, heart enlargement, skin discoloration and hardening (particularly in smokers), cataracts and even arterial stiffness. (If you want to see glycosylation in action, then cut an apple in half and watch it turn yellow and tough). Our aminoguanidine tablets also contain vitamin B6 so there is no need for extra supplementation.

Andro-Pro™ Andro-Pro contains the latest cutting-edge nutritional ingredients to naturally boost free testosterone levels. The most unique ingredient added to Andro-Pro is the recently discovered fructoborate. Fluctoborate is a boron derivative that according to Romanian

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studies is helping to alleviate bone loss and arthritis; but perhaps the most interesting clinical study was done on 13 men. They were given the equivalent of one capsule of AndroPro daily for 60-days, at the end of the 2 months, on average these men experienced serum level increases of vitamin D by 19.6%, DHEA-S up 56% and free testosterone rose by 29.5%. In addition, Andro-Pro also contains the supporting agents of zinc, B6, magnesium and high quality tribulus terrestris. All factors in improving free testosterone production. Adding DIM-Pro™ to your regime can help to reduce estrogen levels and therefore improve free testosterone levels even further.

Arimidex® (anastrozole)

The eggplant cancer cure by Bill Cham Ph.D. covers all aspects of BEC5 Curaderm treatment. Curaderm to regress non-melanoma skin cancers within weeks! For example, one open study with 72 patients had 100% healed skin cancer lesions within just 13-weeks of applying BEC5 Curaderm cream twice daily. “BEC5 Curaderm is a topical preparation which is safe and effective, an ideal therapy for outpatient treatment... It is a cost effective treatment for both primary and secondary skin cancer care.” Dermatologists at the Royal London Hospital

Arimidex contains anastrozole and it is perhaps the most famous of the 3rd generation of aromatase inhibitors. These types of drugs prevent the enzyme aromatase from converting testosterone into estrogens (and vice versa in women) and are approved for breast cancers. Men who have a need to alter the T/E balance (which becomes deranged in the favor of estradiol with age) sometimes utilise Arimidex tablets at approximately 1 mg per week, or 100 mcg per day.

UPDATE: Generics are now available in 100 mcg and 1 mg capsules.

ATP Boost™ ATP-Boost provides 20mg of ATP, the body’s ultimate energy molecule in each capsule. In addition, ATP Boost contains a unique combination of the nutrients acetylL-carnitine and R-lipoic acid that increase mitochondria energy production without the increase in damaging oxidation that usually follows. The result: enhanced energy reserves and reduced aging at the cellular level.

Here are examples of patients before, during and after treatment with BEC5 Curaderm. A typical treatment period from start to finish is 8 weeks. Furthermore, BEC5 Curaderm is known not to harm healthy cells, therefore only destroying cancer cells on and under the skin’s surface.

BEC5 Curaderm® cream BEC5 Curaderm cream was discovered by Dr. Bill Cham on the Oceania island of Vanuatu. Dr. Cham noticed that when the local farmers rubbed the plant called the ‘devil’s apple’ (found in that region and which is related to eggplant) onto the backs on animals that were experiencing skin cancers- that they had considerable success in its removal. It is known that BEC5 Curaderm has now been used by more than 80,000 patients, all with remarkable success. Clinical trials in the UK and Australia have confirmed the ability of BEC 22

“What’s near perfection? BEC5 Curadermit’s a treatment that works nearly every time. It’s incredibly simple to use, has no adverse side effects and is inexpensive compared with other treatments.” Jonathan Wright, M.D. BEC5 Curaderm is known to be effective for all the following conditions:

• • • •

Basal cell carcinomas (BCC) Squamous cell carcinomas (SCC) Keratoses Keratoacanthomas

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• Age spots • Sun spots UPDATE: To achieve the best possible results in the quickest possible time, use HemaGel® and tamanu oil following the BEC5 treatment.

BCI program Dr Garry Gordon is a world expert in detox and chelation (the removal of heavy metals). His oral BCI program is a world leader. Made up of 3 products, it not only provides the right natural materials to help lock-up, remove from tissues, transport through the body and excrete toxins, but also a plethora of protective vitamins, minerals and oils that have been designed to make it as easy as possible to have the most comprehensive all-in-one package. Each sachet in the Beyond Chelation Improved® contains 3 vitamin/ mineral pills, 3 chelation/ detox capsules, 1 omega 3 fish oil capsule, 1 omega 6 & 9 evening primrose capsule and 1 brain capsule containing gingko biloba and phosphatidylserine. This is a superb daily nutritional supplement just by itself, but to avail yourself of the full program you should add two more agents; these are: Bio-En’R-Gy C® a unique high-strength and stabilised vitamin C powder that can be added to water or juice. It also contains ribose for your heart health along with MSM, betaine and bioperine to lower inflammation and problematic lipids. Fundamentally, it is this product that transports the toxins from the tissues sites that Beyond Chelation Improved® has released, ready for them to be excreted. Then it is over to Dr Gordon’s Beyond Fiber®. It contains the best forms of fiber, specifically extracted from brown rice husks and Jerusalem artichoke, in addition with EDTA. This product enables the body to defecate the toxins collected into the gut from the body. Simply add a scoop of the powder into your morning cereals or blend it into your power drink.

Can-C™ eye-drops Can-C eye-drops are the original formula for use in cataract and contains a purified and racemized form of n-acetylcarnosine, a natural di-peptide with potent antiglycating and anti-oxidant properties that prevent lipid peroxidation.

The most commonly expressed initial reports are that glare is significantly improved, (for example night driving is much safer) and color perception is enhanced. What’s more evidence is mounting that Can-C is efficacious for all of the following disorders: cataracts, glaucoma, presbyopia, corneal disorders, eye strain, ocular inflammation, blurred vision, dry eye syndrome, vitreous opacities and lesions, diabeteS mellitus complications, contact lens wearers, (regarding the last point in the list above, Can-C inhibits the accumulation of lactic acid which has greatly benefited those who wear contact lenses, because it enables them to be worn for longer without pain).

Left: A woman’s eye shows the cataract before treatment. Right: 5-months later after use of Can-C eye-drops (two drops twice daily), there is no longer a visible cataract and eyesight has improved. Dr. Kyriazis book, ‘the cataract cure’, details the usefulness and evidence of Can-C eye-drops. Now available from IAS as a FREE e-book: http://www.antiaging-systems.com/can-c-ebook “I am so grateful for the development of Can-C eye-drops, not only have they significantly improved my own eyesight, but many of my patients report most favorably about them too. Now we have a real alternative to eye surgery so Can-C can be considered to be a genuine breakthrough.” Richard Lippman, Ph.D.

Can-C Plus™

Patients in trials placed 2-drops of Can-C into their eyes twice daily. After 6-months of use, 88.9% of patients showed improvement in the clarity of their lens and 90% saw an improvement in their visual acuity. There have been numerous reports of cataract shrinkage and even disappearance with documented evidence that Can-C eyedrops remain effective (and safe) more than 24-months later.

Can-C Plus capsules are specially designed to be used alongside the Can-C™ eye-drops to aid and even boost their effectiveness. As there are a few supplements that can block the action of Can-C eye-drops, Can-C Plus capsules have been carefully designed to avoid them. Three Can-C Plus capsules a day can be taken with food, with or without Can-C eye-drops, although for maximum benefit it is recommended that they are used together.

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Centrophenoxine (Cent-Pro™) Like all good antiaging supplements, centrophenoxine has many useful features with few side effects. From a memory and cognition viewpoint, centrophenoxine has demonstrated significant improvements, most notably its ability to speed up the process of memory recall. One of centrophenoxine’s most noted benefit’s is its ability to effectively and quickly remove a cell toxin that accumulates with age (and Alzheimer’s disease) called lipofuscin. Lipofuscin can make up parts of the socalled Alzheimer brain plaques, but it can even be found in the brains of ‘normal’ aging people as well as other organs such as the heart, the lungs and even the skin- where it forms part of the so-called age or liver-spots, the brown flecks found in ‘aged’ person’s skin. Indeed several weeks of centrophenoxine supplementation has seen removal and lightening of such spots. “Centrophenoxine has shown many facets to improve conditions related to my membrane hypothesis of aging, for example its ability to improve brain-performance, survival time in animal experiments, and to remove the cell aging-pigment called lipofuscin. It has been my antiaging supplement for more than 30-years.” Professor Imre Zs.-Nagy

CoQ10 CoQ10 is a universal energy agent that has significant protective qualities for the heart and the cardiovascular system. An important point- anyone taking a statin drug to lower cholesterol must also be taking CoQ10 since statins lower CoQ10 levels.

UPDATE: Our CoQ10SR™ is a slow release version

combined with cyclodextrin, a new technology that enables greater bioavailability by improving the passage through the stomach into the blood. It has been clinically shown that CoQ10SR™ has up to twice the bioavailability of ‘regular’ CoQ10. Thus depending on how you look at it, CoQ10SR is either double the effectiveness of CoQ10’s of the same dose, or half the price of CoQ10’s of twice the dose!

Crème-Pro™ Cellulite The specialist range of Crème-Pro’s work to attack and defend against all aspects of aging skin problems; here the cellulite contains a high 10% of phosphatidylcholine, proven to help reduce the appearance of cellulite. 24

Simply apply it regularly onto clean, dry skin on the inner thighs and buttocks or wherever cellulite appears. (Avoid the eyes).

Crème-Pro™ Moisturizer Crème-Pro™ Moisturizer does what exactly says on the label. A unique combination of hyaluronic acid, procaine, NADH and vitamin B12 helps to keep skin looking plump, moist and radiant. Simply apply it onto clean dry skin once or twice daily. (Avoid the eyes).

Crème-Pro™ Protector Crème-Pro Protector is a day cream designed to help protect the skin against environmental agents, including sunlight and oxygen as well as pollution. The agents can attack skin and make it age prematurely through their oxidative effects. The most unique agent in the Protector cream is idebenone, it is the single most potent antioxidant yet studied, and rarely found except in the most expensive antiaging skin creams. Apply it onto clean dry skin and use it as a regular day cream. (Avoid the eyes).

Crème-Pro™ Smoother Crème-Pro Smoother is designed to be the alternative to injectable nerve freezing agents such as Botox®. Smoother can be applied to any fine lines such as crows’ feet around the eyes and around the lips etc. It contains synthetic snake venom that temporarily paralyses nerves in the skin, thereby relaxing and unfolding the skin in that region, immediately reducing the wrinkles and producing younger looking skin. (Avoid the eyes).

CurcuminSR™ Curcumin is the active extract of the spice turmeric; it has received a lot of attention for its ability to act as a potent anti-inflammatory. Such actions have been noted of benefit to conditions for cancer, heart disease, arthritis and even pain relief; plus a recent study showed curcumin is able to reduce the brain plagues found in Alzheimer patients. The CurcuminSR™ we supply delivers curcumin in a special micronized, 8 hour sustainedrelease matrix to increase absorption and bioavailability. By

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being released slowly blood levels stay consistently elevated and CurcuminSR™ is better absorbed/ more bioavailable than regular curcumin supplements.

Deprenyl (selegiline) Parkinson’s disease is characterised by the loss of the brain neurotransmitter dopamine and deprenyl helps to prevent this loss by acting on the specific enzyme MAO-b. Professor Knoll also believes that deprenyl very significantly increases PEA (phenylethylamine) and that this may have an even more significant function that the MAO-b inhibition, (for more details on this please read Professor Knoll’s excellent book on the subject- ‘the brain and its self’). Professor Jozeph Knoll of Debrechen University in Hungary- the inventor of deprenyl In addition to improving dopamine levels, deprenyl has also been shown to help rebalance serotonin, noradrenaline and acetylcholine levels and whilst the uses remain ‘off-label’ deprenyl has been used for Alzheimer’s and even cancer treatments. Our focus here is upon deprenyl’s enhancement of dopamine, which is a key brain chemical responsible for drive, focus and well being and even libido (especially for men). The experiments of Professor Jozeph Knoll dramatically extended the lifespan of rats who were given deprenyl. Even the first rat to die that was treated with deprenyl died after the last rat not treated with deprenyl died.

Esnatri™ cream (bio-identical estrogens) Esnatri cream is the world’s only bioidentical estrogen cream to replicate the work of Dr. Jonathan Wright. Dr. Wright has highlighted that the ‘average’ woman produces estrogens in the ratios of estriol 90%, estradiol 7% and estrone 3% and these are the exact same ratios found inside Esnatri. Each 1ml of Esnatri cream provides 2mg in total of the triple estrogens and it enables a precise, natural and indeed bioidentical hormone replacement therapy for women concerned about the menopause. IAS provides dose and timing advice from Dr. Wright for both estrogens and progesterones with every purchase. The additional use of bioidentical progesterone should be used along with an estrogen replacement program. For further information on estrogens we recommend one of Dr. Thierry Hertoghe’s Hormone handbooks.

Gamibetal® (GABOB) Each Gamibetal tablet contains 500mg of the GABA related molecule- GABOB; it is technically the closest legal molecule to GHB. The approved use of Gamibetal in Europe is to help with epilepsy but like GHB – GABOB has been shown to improve growth hormone release significantly when taken before bedtime. GABOB does not have the ‘sleep inducing’ effects of GHB, but it can cause some sedation if taken in high doses.

GHRP2 GHRP2 is growth hormone releasing peptide number 2 and featured in this magazine’s lead article. It is a potent releaser of HGH for fat loss and is particularly synergistic with sermorelin. It is best taken in the morning, by swallowing 4ml of the liquid.

UPDATE: GHRP2 is synergistic with sermorelin.

This graph highlights the loss of dopamine with age, on average 13% per decade past the age of 40 for the average person, but far greater for those suffering from Parkinson’s disease

Glutathione (also see ACF228™ Breathe-Easy)

The idea behind the antiaging use of deprenyl is to use very small doses regularly in order to help maintain healthy dopamine levels and thus improve cognitive function and help to maintain function at a better level for much longer. Note: The liquid version titrates selegiline HCL as 1 drop = 1mg.

Glutathione is a potent antioxidant that helps to prevent damage to important cellular components that can be caused by reactive oxygen species such as free radicals and peroxides. Glutathione is principally synthesized inside the body and is relatively poorly obtained via the diet. The Advanced Cellular Glutathione supplement is a spray providing nano sized particles for sub mucosal absorption to create instant bioavailability.

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Hair-Pro™ Hair-Pro is the very latest development to help induce hair growth and it contains the absolute latest cutting-edge growth factor technologies. Hair Pro is a unique proprietary topical liquid blend that includes finasteride, (the DHT blocking drug used orally for years as a hair loss treatment), but it also contains a plethora of aminoacids that act as hair growth factors including bFGF, TRX, VEGF and IGF-1. In addition there is aminosyn to promote protein synthesis (hair strength), hyaluronic acid to aid hair hydration (thickness) and dexpanthenol to cleanse the pores of the blocking fat- sebum which can block nutrition from the hair root. No finer multi factorial topical anti-alopecia product exists on the market today. Use it in combination with the Scalproller to improve uptake into the scalp.

HemaGel® HemaGel has been created in the Czech Republic and specially designed to help improve the treatment times of wounds, scratches and cuts, in some cases reducing the start-to-finish treatment time by as much as 50%. It does this in two ways, (1) by absorbing harmful and damaging free radicals and (2) by also helping to absorb blood and puss extrudes, thus also keeping the wound cleaner. HemaGel can be recommend for use after BEC5 Curaderm applications to speed up the skin’s healing and also as an excellent product to have in the First Aid cabinet- just in case! Simply apply the HemaGel daily directly onto a cleaned (and disinfected) wound, and then apply a non-textile bandage over it.

Hydergine (ergoloid mesylate) Hydergine is an extract of a fungus that grows on rye called ergoloid mesylate and its approved uses have been to aid persons with memory disturbances, Alzheimer’s disease and even for persons who have suffered from shock related to electric, drowning or suffocation. This is because hydergine is an excellent provider of stabilising the levels of oxygen in the brain and has been shown to improve levels when they are too low and even decrease levels when they are too high. The result of this optimised oxygen availability in the brain is an ability to do more mental workload without becoming tired. Accordingly, hydergine can be a good tool to battle through boring paperwork or a long drive home in the dark. A fascinating animal experiment showed a special ability for hydergine to improve mitochondrial condition. The mitochondria are vital organelles found in every cell of our body responsible 26

for the generation of ATP, the universal energy molecule. Unfortunately mitochondrial efficiency declines as we age and this has been linked to disrupted repair mechanisms. However an Italian study highlighted those old animal mitochondria can be improved with hydergine supplementation. Hydergine has also been attributed to stimulate the growth of dendrite nerve fibers, since these connective strands are known to decline in aging this is another antiaging feature of hydergine. Some have even linked the density and numbers of dendrite fibers to the level of I.Q. In summary, hydergine helps to protect against conditions of hypoxia and peroxidation, important factors to guard against a stroke and generalised brain injuries. Hydergine can extend the boundaries of mental workload and energy, fighting against boredom and may even provide some groundwork for raising the levels of intelligence. The liquid form can be titrated in small doses and may be more suitable for those who want low doses or have trouble swallowing tablets. The Bertonin-Freddari et al, 1994 study highlights that hydergine can improve the size, volume and number of mitochondria in old animals- towards the youthful example; as is shown here the difference between young, old (without hydergine) and old (with hydergine) is significant.

Melatonin (MZS™) Melatonin is one of nature’s remarkable substances and made in response to darkness by the pineal gland. Its benefits to help overcome jet lag and shift work have become quite well known and indeed it is useful for this purpose since adequate melatonin availability enables our bodies to be correctly in tune with our circadian rhythms, these rhythms dictate our hormonal cyclicity and this cyclicity ultimately determine our aging and our level of immunity. Unfortunately melatonin secretions decline with aging. Professor Pierpaoli has published widely on melatonin, principally through the New York Academy of Science and at the meetings of the Stromboli conferences on aging and cancer- which IAS is delighted to support. What is important to know about melatonin is that Professor Pierpaoli advocates a 3mg dose to (his words) “put the pineal to sleep.” In addition, it is also vital to use a melatonin that produces a night peak of melatonin that is the same as the peak produced by the pineal itself. This he has achieved using specific excipients in his own formula ‘MZS™’ (which also contains the additional synergistic ingredients of zinc and selenium).

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• Saw Palmetto: This herb helps to block the damaging effects of DHT, a known hair growth restrictor.

This graph highlights that Professor Pierpaoli’s Melatonin Zn Se formula mimics the night peak of melatonin. Note that sublingual melatonin tested peaks too soon and that time released formulas peak too late.

• Resveratrol: The remarkable protective agent found in red grape skins has recently been noted to help induce hair thickness. • Melatonin: This has been documented (and was the subject of a patent) to help prevent hair loss. • Plus, there is now a sixth active ingredient in MinSaw and that’s retinolic acid (also known as tretinoin). This super high strength vitamin A has long been known to improve skin condition by enhancing blood flow to the skin and in the same way, here in MinSaw this ingredient improves the blood supply around the hair root, helping it to be stronger and healthier. Just apply a small amount of MinSaw daily to the scalp and see the results for yourself in a few weeks’ time. Use it in combination with the Scalproller to improve uptake into the scalp. Also recommended is the Nanogen hydration spray to prevent scalp dryness and flaking.

Here are some before and after Fundus photos showing the benefit of Melatonin Zn Se. They highlight dramatic improvements to both wet and dry forms of macular degeneration. In a trial published in the New York Academy of Science, 110 eyes, (100 patients) with both wet and dry forms of ARMD were treated only with 1 tablet of Melatonin Zn Se nightly. After 6-months 90% of the treated patients’ eyes had significant improvements to their condition. This is simply remarkable compared to the current approved therapy for ARMD which involves injecting the eye quarterly, (costs $1000+) with 50% improvement at 24-months! For further detailed information about melatonin and Professor Pierpaoli’s work we recommend his book ‘the key of life.’ it is now available as a FREE e-book.

Naltrexone The results of low dose naltrexone, (widely known as LDN) therapy have been remarkable. Originally, the use of naltrexone was in the management of dependence on opioid and alcohol. But it was Dr. Bernard Bihari in the 1980’s who first used low dose naltrexone for the treatment of HIV and then for a number of other autoimmune diseases such as multiple sclerosis, Crohn’s disease and many immunological related diseases, and especially in the treatment of MS, where patients have reported an improved quality of life. A leading study has established that by maintaining regular nightly LDN, less than 1% of the MS sufferers experience fresh MS attacks. IAS supplies the LDN dose of 4.5 mg.

Oxytocin (Oxy-Pro™)

MinSaw™ MinSaw has been updated numerous times, but now it’s in its best formula ever. MinSaw provides all of these proven hair growth and protectors in its latest formula: • Minoxidil: Perhaps the best known agent to help stimulate hair growth, which it does by increasing nitric oxide promotion in the root of the hair and in so doing delivers more nutrition for the hair to grow faster. MinSaw takes has one of the most potent amounts of minoxidil in it at 8%. • Vitamin C: It’s known to help stimulate hair growth and ‘clean’ the root bulb, thus MinSaw now also contains the active form of L-ascorbic acid.

Oxytocin is a hormone produced in the hypothalamus and secreted into the blood by the pituitary gland. Oxytocin has been described in detail in Dr. Thierry Hertoghe’s latest book- Passion, Sex and Adventure, the oxytocin story. It is coming to light that oxytocin has pain curbing abilities and could be efficacious in fibromyalgia. Other studies are highlighting that oxytocin could be efficacious in the treatment of autism and even schizophrenias. But it is perhaps its ability to enhance bonding between partners that is likely to attract most attention. From the sexual standpoint oxytocin

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has been known to increase ejaculate in the male and in females oxytocin has had significant libido enhancement effects, including the inducement of multiple orgasms. We have worked alongside Dr. Hertoghe to create a practical and efficacious sublingual trouche (that’s a gel like tablet) typical doses are 5 to 20 IU as required. (The square troches can be cut in half from corner to corner easily).

UPDATE: Oxy-Pro™ is a new nasal spray version of oxytocin (delivering 10 IU per spray) in addition to our 20 IU sublingual trouches.

Peptide Bioregulators These are the very latest technology from Professor Khavinson in Russia. They utilise highly specific peptides extracted from Danish bovine sources. These peptides have been shown to be a short-cut to protein synthesis by activating directly with their receptive genes. Therefore their action is to ‘reinvigorate’ their respective gland/ organ, to induce their biological reserve and essentially rejuvenate their processes.

1. 2. 3. 4. 5. 6. 7.

Cerluten® is the peptide for the central nervous system. Glandokort® is the peptide for the adrenal glands. Libidon® is the peptide for the prostate gland. Pielotaks® is the peptide for the kidneys. Testoluten® is the peptide for the testes. Ventfort® is the peptide for the blood vessels. Visoluten® is the peptide for the eye retina.

A recommended course is to take 2 capsules each day for 10-days (total 20-capsules). For general health support this can be repeated again in 6-months’ time, thus only 2 boxes are required for a year! For those in greater need the course can be repeated every 3 months, or 2 months or each month if necessary.

Piracetam (Nootropil®; also see Anacervix®)

Piracetam was the very first nootropic, (commonly called smart drugs) to be developed and despite being one of the very first products that IAS offered when we went online in 1991, it still remains one of our best selling products today! Why? Because it is a very beneficial memory agent that has a great safety record, with very few side effects, plus it is cost effective. Piracetam has been shown to have a better/ lower toxicity profile than salt. Maybe because it has a very small impact upon brain chemical levels, but rather helps to improve electrical communication across the brain’s corpus callosum. 28

The corpus callosum is the bundle of nerves that separates the two hemispheres of the brain. In medical terms piracetam is used to improve short term memory and to treat a wide variety of senile dementias as well as autism and Down’s syndrome and can also assist with travel and altitude sickness. Note: IAS offers the original UCB brand called Nootropil which is available in tablet and liquid form. The liquid form was specifically designed for children (it is sweetened with saccharin), but its advantages include being able to titrate low doses (if required) and also aid any person who has difficulty swallowing tablets.

Progesterone Progesterone is often the ‘missing’ hormone in the treatment of female menopause. What we mean by this is that whilst estrogen treatments, (see Esnatri™ for details) are often considered as a primary replacement hormone for women of that certain age, progesterone is often forgotten about. The best known action of progesterone is its ability to help build bone mass and since progesterone levels fall rapidly in menopause it contributes to osteoporosis in elderly women. Progesterone is strongly advocated to be taken in combination with any estrogen replacement program.

UPDATE: Our progesterone strength is PPharma grade and twice the dose that is found in US health food stores. Progesterone levels decline in women with age; in some cases progesterone levels can be undetectable! We recommended; one of Dr. Hertoghe’s hormone handbooks for further information about progesterone.

PQQ (pyroloquinoline quinone) PQQ is in reality the most newly discovered vitamin. In more than 200 studies it has been shown to improve overall energy levels, cognitive function and memory, reduce mitochondrial degradation and increase skin elasticity. Furthermore, it acts as a neuro and cardio protectant and helps to enhance nerve growth.

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Retin-A®

(Retirides®)

Retin-A contains retinolic acid, a pure form of vitamin A that enhances blood supply to the skin’s surface and transforms the appearance of thicker, tougher skin into more youthful looking, elastic and fresher skin but speeding up the process of the delivery of nutrition to the skin and the removal of waste materials from it. Retin-A is the cream of choice for cosmetic surgeons to speed up the wound healing of cosmetic surgery and scarring etc.

UPDATE: We now also supply the new Retin-A® micro-gel

which is designed to sit on the skin surface and release slowly.

Sermorelin

(Serm-Pro™)

Sermorelin is a breakthrough development in the field of growth hormone (GH) replacement, for sermorelin is the bioidentical molecule used by the pituitary gland to help stimulate production and release of GH into the bloodstream. Sermorelin is not GH; GH is a complicated molecule consisting of 191 amino acids, but rather sermorelin is a 29 chain of aminoacids, but importantly it is the first 29 aminoacids of GH, the part responsible for activation. This is what makes sermorelin stand head and shoulders over all previous agonists of GH, because sermorelin is GH site specific and therefore effective. What is more, sermorelin has a negative feedback loop (unlike GH itself), so the issues of overdosing and safety associated with injections of GH are minimized/ completely avoided with sermorelin. And now for the first time it has been shown that sermorelin is stable at room temperature and efficacious when used sublingually. These are additional factors that favor sermorelin as the next generation of GH activators. We are excited to introduce this sublingual liquid version of sermorelin which has been created with the close cooperation of Dr. Richard Walker of SARA (Scientific Applied Research into Aging), a world renowned antiaging expert.

the cell divides and the theory is that this is a significant part of the destructive process of aging. Animals with longer telomeres enjoy a more productive and healthier older age and also appear to live longer. The benefits for humans may not be clear yet, but TA65 production is carefully controlled by TA Sciences, who purchased the technology from the Geron Corporation. It remains a fact that whilst other substances have claimed to delay the shortening of telomeres, only TA65 has been clinically proven (and published) to actually lengthen short telomeres in humans. If you want the cutting-edge of antiaging supplementation and the best possible chances for longer telomeres, then TA65 is currently your best and indeed only clinically proven choice.

Thyroid (Armour®; Synthroid®) A decline in the secretion of hormones from the thyroid gland (hypothyroidism) can result in poor concentration, confusion, memory problems, cold hands and feet, weight gain, menstrual problems, sleep disorders, dry skin, thinning hair and low energy levels. An underactive thyroid is also a major cause of a common painful musculoskeletal condition known as fibromyalgia. Aging often leads to hypothyroidism, one of the most famous thyroid experts, Dr. Broda Barnes states that as many as 40% of the adult population could be hypothyroid. Thyroid supplements come in two forms; these are whole or natural supplements and synthetic supplements. It is almost always better to use a whole-natural thyroid extract because the synthetic versions usually only comprise of one of the thyroid hormones, (such as, T3 or T4), whereas, whole-natural thyroids cover a fuller spectrum of thyroid hormones (including T1, T2, T3 and T4). By measuring a particular hormone known as Thyroid Stimulating Hormone (TSH) it can be determined whether supplementation is necessary. However there are simple measures such as noticing if one regularly has cold hands and feet, problems adapting to temperature changes, or checking

UPDATE: ERFA now available in value 500 tablet packs

UPDATE: Now also available in intranasal form.

TRH (Abaris™)

TA65® TA65 contains a highly purified specialized extract of the Chinese herb astragalus. What makes this supplement totally unique is that it is the first natural substance that has been proven to act as a telomerase activator and to extend telomeres in humans (in-vivo). Telomeres are the strands on the ends of chromosomes that shorter each time

TRH is a hypothalamic hormone whose real uses and benefits are just coming to the fore, primarily after research conducted by Dr. Walter Pierpaoli, the physician and scientist who exposed the benefits of melatonin to the world. Dr. Pierpaoli’s research suggests that TRH is a ‘master’ hormone responsible not just for helping to adjust thyroid hormones (its principle recognised role), but in helping to recorrect many imbalances throughout the body.

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

29


For example in his animal experiments TRH supplements have encouraged old animals to:

prostate conditions can benefit by less trips in the night to urinate.

• Re-establish spermegenesis, (reversing the age-related

But vasopressin is also responsible for the laying down of memories in the hippocampus and it has been used to treat amnesia. In particular, it is cited by many for memory imprinting, this is the learning of new material before it is experienced. Therefore taking 1 or 2 sprays into each nostril 15-minutes before an exam, meeting or lecture etc., can induce a better detailed recall of events later.

dysfunction of their testes).

• Correct kidney dysfunction, (a significant finding for renal issues).

• Correct pancreatic dysfunction, (a significant finding for diabetic issues).

• Improves many lipid profiles and aids weight loss when used over a few months.

IAS is delighted to be the first organisation in the world to offer a sublingual TRH tablet.

Vasopressin Vasopressin is a porcine extracted source for this pituitary hormone which has a number of interesting roles. Its approved medical use is to prevent frequent urination in conditions such as diabetes insipidus. For example, men with

Zeolite Zeolite is a volcanic rock that is widely used for its remarkable chelation properties, that is its ability to trap heavy metals inside its electron cage. It should be noted that it comes in many different qualities however, from cat-litter (to trap the smell) up to the ZeoGold® brand, so effective it is the quality chosen by NASA to purify the water supply for astronauts on route to Mars! IAS supplies the ZeoGold capsules which must be broken and allowed to dissolve into water and drunk, or the ACZ nano-spray. These are both highly effective agents designed to remove many unwanted toxic metals from the tissues.

Centrophenoxine The Smarter Way to Combat Mental Decline

Centrophenoxine is a Nootropic or smart drug proven to increase brain power, improve longevity and create an overall sense of mental alertness. Centrophenoxine ‘cleans out’ Lipofuscin the build-up of potassium in the brain, heart, lung and skin cells that accumulates over a lifetime, improving their function and their longevity.

Pioneering Centrophenoxine researcher Imre Zs Nagy uses our Cent Pro, so if you want the experts choice you need our Centrophenoxine.

Cent-Pro™ 60x 250mg tablets $29.99 30

Restrictions may apply please see IAS terms and conditions for full details


Product A-Z listing Here is an alphabetical listing of IAS stocked products. See our cross-reference list of disorders that relate to these individual products. Much more information is available from our website including full ingredient/ excipient listings, doses and side effects etc. If you need any further information or can’t find what you require, please don’t hesitate to contact us. The inside back cover has all our details.

Testimonials “IAS has shown great vision and leadership, as an organisation focused mainly on the provision of contemporary medical interventions against aging, and in also supporting the SENS Foundation’s efforts to hasten the development of much more powerful future interventions.” Dr. Aubrey De Grey “IAS is an outstanding resource for the finest, most-up-to-date news and information on healthy aging. They also offer products of the highest integrity and efficacy. In fact, IAS is the world’s greatest source (often the only source) for the most cutting-edge and advanced nutrients to ensure optimum health span and maximum life span.” Dr. Nicholas Perricone

The following index underneath certain products means that it can’t be shipped there or known restrictions apply. For example: Can’t be shipped to Australia (or New Zealand) Can’t be shipped to Canada Can’t be shipped to EU Can’t be shipped to Japan Can’t be shipped to UK

“IAS has a history of making crucial but difficult to access medications available to patients throughout the world. IAS is one of the pioneering societies in anti-aging medicine that has helped this new medical specialty move forward.” Dr. Thierry Hertoghe “I am a 77 year old physician who has practiced medicine for nearly half a century. My anti-aging research has permitted me to overcome serious health problems. Everyone can do this, but it requires specialized knowledge and the highest quality products. IAS is a vital link in my anti-aging program because they continually provide both accurate information AND the high quality products we all require, if we are to achieve our maximum intended useful lifespan.” Dr. Garry Gordon “Every adult has the right to take care of his or her own personal health as he or she chooses. In the 20th and 21st centuries, this universal human right has been nearly obliterated by an ocean of nanny-state regulation and deliberate suppression of information by bureaucracies, with hidden and not-so-hidden agendas. International Anti-aging Systems is a beacon of useful health care information and a literal island of freedom of health care product choice in our otherwise un-free health care world.” Dr. Jonathan Wright See them all at: antiaging-systems.com/testimonials/index.htm

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1st Line™ (OSCN, thiocyanate)

1 complete kit retail $89 IAS price $79.99 Item Code: 675

5HTP (5-hydroxy-tryptophan)

5HTP-Pro™ 60x 50mg capsules retail $20 IAS price $17.49 - Item Code: 327

Acarbose (Glucobay®)

Glucobay® 30x 100mg tablets retail $24 IAS price $19.99 - Item Code: 373

Acetyl-L-Carnitine (see ATP-Boost™)

ACF228™

ACF228™ 45 capsules retail $59 IAS price $49.99 - Item Code: 621 NEW: ACF228™ Breathe-Easy 1 inhaler retail $140 IAS price $129.99 - Item Code: 810

Adenosine Triphosphate (see ATP-Boost™)

Active H-Minus®

(hydrogen)

Active H-Minus® 90 effervescent tablets retail $44 IAS price $39.99 - Item Code: 783

Anacervix®

Anacervix® 30x 420mg capsules retail $30 IAS price $21.99 - Item Code: 163

Andro-Pro™

NEW: Andro-Pro™ 60 capsules retail $55 IAS price $49.99 - Item Code: 758

Aniracetam (Ampamet®)

Ampamet® 20x 750mg tablets retail $55 IAS price $47.49 - Item Code: 6 NEW: Ani-Pro™ 20x 750mg capsules retail $35 IAS price $29.99 - Item Code: 777

Arginine (see Beyond GHS®; Nitric-Pro™; VigorPro™), Argireline (see Crème-Pro™ Smoother), Arterial wave velocity (see Bio-Clip & Bio-Cuff)

Arimidex® (anastrozole)

NEW: Anastrozole 28x 1mg tablets retail $149 IAS price $129.99 - Item Code: 111

Adrafinil (Olmifon®)

NEW: Anastro-Pro™ 28x 100mcg capsules retail $35 IAS price $29.99 - Item Code: 779

Olmifon is no longer manufactured.

Artemisinin

NEW: Adra-Pro™ 40x 300mg capsules retail $60 IAS price $49.99 - Item Code: 775

Agomelatine (see Valdoxan), Agrimony (see Nexiclear®)

Aldosterone

Aldosterone 15x 125mcg capsules retail $120 IAS price $94.99 - Item Code: 687

Alfalfa (see Dr Gordon’s Organic Greens®), Allicin (see garlic), Alpha lipoic acid (see lipoic acid)

Aminoguanidine (pimagedine) Amino-Pro 100 x 75mg tablets retail $35 IAS price $29.99 - Item Code: 303

32

Aminohydroxybutyric acid (see GABOB), Aminophylline (see Crème-Pro™ Cellulite), Aminosyn (see Hair-Pro™), Amphoteric surfactants (see Nanogen® shampoo, Nanogen® conditioner)

Artem-Pro™ 90x 100mg capsules retail $25 IAS price $22.49 - Item Code: 642

Ascorbyl palmitate (see Crème-Pro™ Protector, Crème-Pro™ Smoother), Astaxanthin (see Crème-Pro™ Protector), Astragalus extract (see TA65®), ATP (adenosine triphosphate, see ATPBoost™)

ATP-Boost® (Adenosine Triphosphate) NEW: ATP-Pro™ 60x 20mg tablets retail $35 IAS price $29.99 - Item Code: 821

Azilect® (rasagiline)

NEW: Rasagiline-Pro™ 30x 1mg capsules retail $99 IAS price $89.99 - Item Code: 827

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com


Banaba Extracts (see Diet-Pro™), Barley grass (see Dr Gordon’s Organic Greens®), BCI (see Beyond Chelation Improved®)

bFGF (see Hair-Pro™), BHT (butylhydroxytoluene, see ACF228™)

BEC5 Curaderm® cream

complete kit retail $850 IAS price $799.99 - Item Code: 653

BEC5 Curaderm® 20ml tube cream retail $140 IAS price $129.99 - Item Code: 403

Beetroot (see Neo40®)

Benfotiamine (Milgamma Mono®) Milgamma Mono® 30x 50mg tablets retail $21 IAS price $18.99 - Item Code: 273

Benzoic acid (see Gerovital®), Beta alistine (see L-carnosine), Beta glucan (see Beyond Chelation Improved®, Nanogen® hydrator, Nanogen® serum), Betaine (see TMG), Beta sitosterol (see Beyond Chelation Improved®), Beyond Any Multiple® (see Beyond Chelation Improved®)

Beyond B12®

Beyond B12® 40x 2mg sublingual tablets retail $30 IAS price $29.99 - Item Code: 477

Beyond Bone Defense® (see Bone-Pro™)

Beyond Chelation Improved® (BCI)

Bio-CUFF™

Bio-CUFF® one complete kit retail $150 IAS price $124.99 - Item Code: 715

Bio-En’R-Gy C®

Bio En’R-Gy C® 200 grams powder retail $60 IAS price $59.99 - Item Code: 591

Bioflavonoids (see Wobenzym®), Biological age measurement (see Bio-CLIP™, PulmoLife®), Bioperine (see Bio-En’R-Gy®), Biotin (see Beyond B12®; Beyond Chelation Improved®, HRT Plus®; BCI; Nitric-Pro™), Blood oxygenation measurement (see Bio-CLIP™), Blood pressure measurement (see Bio-CUFF™), Blueberry extracts (see Andro-Pro™)

Boluoke® (Lumbrokinase)

NEW: Boluoke® 60 capsules retail price $108 IAS price $92.99 - Item Code: 839

Bone-Pro™

Beyond Chelation Improved® 30 sachets retail $80 IAS price $79.99 - Item Code: 351

Beyond Clean II® (Calcium EDTA & Zeolite)

NEW: Beyond Clean II® 32 oz. bath salts retail $70 IAS price $69.99 - Item Code: ???

Beyond Fiber®

Beyond Fiber® 504 grams powder retail $50 IAS price $49.99 - Item Code: 436

Beyond GHS®

Bio-CLIP™

Beyond GHS® 75 tablets retail $90 IAS price $89.99 - Item Code: 353

Bone-Pro™ 180 capsules retail $40 IAS price $29.99 - Item Code: 0721

Borate (see Andro-Pro™, Can-C™), Boron (see Andro-Pro™, Beyond Chelation Improved®, BCI, Bone-Pro™, Cardio-Pro™, Prostate-Pro™), Boswellin (see Joint-Pro™)

Bromocriptine (Parlodel®)

Parlodel® 30x 2.5mg tablets retail $25 IAS price $21.49 - Item Code: 58

Bromelain (see Digestif®, Wobenzym®), Buxamin (see GABOB), Calcium (see Bone-Pro™, BCI, NitricPro™)

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

33


Cabergoline (Dostinex®)

Dostinex® 8x 0.5mg tablets retail $99 IAS price $89.99 - Item Code: 612

Caffeine (see Crème-Pro™ Cellulite), Calcium (see Bone-Pro™, Beyond Chelation Improved®, NitricPro™)

Can-C™ eye-drops

Can-C™ 2x 5ml vials retail $45 IAS price $39.49 - Item Code: 456

Can-C™ Plus

Can-C Plus™ 90 capsules retail $40 IAS price $34.99 - Item Code: 629

Carboxymethylcellulose (see Can-C™)

Cardio-Pro™

Cardio-Pro™ 90x 215mg capsules retail $34 IAS price $27.49 - Item Code: 500

Carnosine (L-carnosine, see ACF228™, Can-C™; Cardio-Pro™, Can-C Plus™, L-carnosine), Catalase (see ACF228™)

Centrophenoxine (meclofenoxane) Cent-Pro™ 60x 250mg tablets retail $35 IAS price $29.99 - Item Code: 243

Cerebrolysin®

Cerebrolysin® 5x 5ml i.m. ampoules retail $99 IAS price $89.99 - Item Code: 595

Chasteberry (see DIM-Pro™), Chlorella (see Dr Gordon’s Organic Greens®), Choline (see Beyond Chelation Improved®, centrophenoxine, krill, Vigor-Pro™), Chondroitin (see JointPro™; Hy-Col™), Chromium (see Beyond Chelation Improved®; Diet-Pro™), Chromium polynicotinate (see ACF228™, Diet-Pro™)

Cialis® (tadalafil)

Cialis® 4x 20mg tablets retail $85 IAS price $79.99 - Item Code: 296

34

Cinnamon extracts (see Diet-Pro™)

Ciproxin® (ciprofloxacin)

Ciproxin® 10x 500mg tablets retail $35 IAS price $29.99 - Item Code: 640

Citrus bioflavonoids (see Beyond Chelation Improved®), Cocos nucifera oil (see Nanogen® conditioner)

Cobalt chloride

Cobalt 100x 200mcg tablets retail $50 IAS price $44.99 - Item Code: 646

Coccinia indica extracts (see Diet-Pro™), Coenzyme Q10 (see CoQ10), Collagen (see Hy-Col™)

Colchicine

NEW: 40x 1mg tablets retail $19 IAS price $14.99 - Item Code: 835

CoQ10SRTM (Coenzyme Q10, ubiquinol, biquinone)

NEW: CoQ10SRTM 30 x 100mg slow release capsules retail $39 IAS price $24.99 - Item Code: 824 Copper (see Beyond Chelation Improved®), Cortisol (cortisone, see Fludrocortisone, hydrocortisone), Curcumin (see Joint-Pro™), Cranberry extracts (see Andro-Pro™)

Crème-Pro™ Cellulite

NEW: Crème-Pro™ Cellulite 30ml pump cream retail $30 IAS price $27.99 - Item Code: 828

Crème-Pro™ Moisturizer

NEW: Crème-Pro™ Moisturizer 30ml pump cream retail $40 IAS price $37.99 - Item Code: 829

Crème-Pro™ Protector

NEW: Crème-Pro™ Protector 30ml pump cream retail $55 IAS price $49.99 - Item Code: 830

Crème-Pro™ Smoother

NEW: Crème-Pro™ Smoother 30ml pump cream retail $65 IAS price $59.99 - Item Code: 831

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com


Digestif™

Cresote bush (see Digestif®)

CurcuminSR™ (slow release) NEW: 30x 125mg capsules retail $25 IAS price $21.49 - Item Code: 841

Cycloastragenol (see TA65®), Cresote bush (see Digestif®), Cyclodextrin (see CoQ10SR™), Cyprenil® (see deprenyl)

D3 (vitamin D)

NEW: D3-5000™ 100x 5000 IU capsules retail $20 IAS price $12.49 - Item Code: 843

Digestif® 60 capsules retail $20 IAS price $15.99 Item Code: 626

Di-IndolylMethane (DIM, see ACF228™, DIM-Pro™), DIM (see ACF228™, DIM-Pro™), Dimethicone (see Nanogen®)

DIM-Pro™

DIM-Pro ™ 90 capsules retail $40 IAS price $32.49 - Item Code: 428

Daidzen (see Bone-Pro™; Prostate-Pro™)

DMAE (dimethylaminoethanol, see centrophenoxine, Crème-Pro™ Smoother), DMSA (dimercaptosuccinic acid, see ACF228™, Detox-Pro™), Docosahexaenoic acid (see DHA), Dostinex® (see cabergoline)

Deprenyl (selegiline)

Doxycycline

NEW: D3-Pro™ 12x 50,000 IU capsules retail $30 IAS price $22.49 - Item Code: 689

Jumex® 50x 5mg tablets retail $69 IAS price $59.99 - Item Code: 35 Dep-Pro™ 20ml/ 300mg liquid (HCL) bottle retail $90 IAS price $84.99 - Item Code: 746

Dercos® (aminexil)

Dercos® 200ml bottle shampoo retail $25 IAS price $21.99 - Item Code: 17

Desmopressin (Minurin®, also see vasopressin)

Minurin® 2.5ml nasal spray retail $35 IAS price $32.49 - Item Code: 229

Detox-Pro™ (DSMA)

Detox-Pro™ 45 capsules retail $30 IAS price $24.99 - Item Code: 0716

DHA (docosahexaenoic acid, see krill), Diapid® (see vasopressin)

Diet-Pro™

Diet-Pro™ 90 capsules retail $45 IAS price $35.99 - Item Code: 430

Doxycycline 8x 100mg capsules retail $25 IAS price $21.99 - Item Code: 164

D-pantethine (see Can-C Plus™), D-panthenol (see Nanogen® conditioner)

Dr. Gordon’s Organic Greens

Organic best of greens® 10 oz. bottle powder retail $35 IAS price $34.99 - Item Code: 688

Dutasteride (Avodart®; Avodart®) Avodart® 30x 0.5mg tablets retail $89 IAS price $79.99 - Item Code: 276

EDTA (ethylene diamine tetraacetic acid, see Beyond Chelation Improved®, Beyond Clean®, Beyond Fiber®), Eldepryl® (see deprenyl), EPA (eicosapentaenoic acid, see krill), Ergoloid mesylate (see hydergine, nicergoline)

Esnatri™ cream (bio-identical triple estrogen cream)

Esnatri™ 50ml 100mg cream retail $55 IAS price $49.99 - Item Code: 25

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

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Essential Daily Defence® (see Beyond Chelation Improved®), Estradiol (see Esnatri™), Estriol (see Esnatri™), Estrone (see Esnatri™), Eurycoma Longifolia (see Vigor-Pro™)

Finesteride (Proscar®; Propecia®,

Gamalate B6® 60x 250mg tablets retail $20 IAS price $17.99 - Item Code: 27

Garlic (see see Beyond Chelation Improved®)

also see Hair-Pro™)

Gengigel® mouthwash

Proscar® 15x 5mg tablets retail $40 IAS price $37.49 - Item Code: 67

Genotropin® (see HGH)

Florinef® (see Fludrocortisone)

Gerovital-H3®

Finesteride generic 28x 5mg tablets retail $40 IAS price $34.99 - Item Code: 749

Fluconazole (Diflucan®; Loitin®) Loitin® 7x 50mg capsules retail $39 IAS price $29.99 - Item Code: 307

Folic acid (folate, see ACF228™, Beyond Chelation Improved®, Beyond B12®; HRT Plus®, Joint-Pro™, Lithium-Pro™, Nitric-Pro™, Vigor-Pro™), Forced Expiry Volume- Lungs (see PulmoLife®)

Fludrocortisone

Fludro-Pro™ 100x 20mcg tablets retail $20 IAS price $14.99 - Item Code: 759

Fructoborate (see Andro-Pro™), GABA (gammaaminohydroxybutyric acid, see Gamalate B6®, picamilone)

Gengigel® 150ml bottle liquid retail $19 IAS price $14.99 - Item Code: 550

Gerovital-H3® 5x 5ml ampoules retail $59 IAS price $49.99 - Item Code: 258 Gerovital-H3® 25x 100mg tablets retail $35 IAS price $29.99 - Item Code: 29 GH3-Pro™ 60x 100mg tablets retail $20 IAS price $17.99 - Item Code: 360

GH (growth hormone, see HGH), Ginkgo biloba (see Beyond Chelation Improved®, Vigor-Pro™), Glucophage (see metformin), Glucosamine (see Joint-Pro™), Glucuronolactone (see Detox-Pro™)

GHRP2

NEW: GHRP2-Pro™ 120ml 600mg liquid bottle retail $180 IAS price $159.99 - Item Code: 765

Glutathione (also see ACF228™

Gabapentin (Neurontin®)

Breathe Easy)

GABOB (also see Gamalate®)

Glycerine (glycerin, see Can-C™, Nanogen® hydrator, Nexiclear®), Glycosides (see BEC5 Curaderm®), Grape fruit extract (naringenin, see Prostate-Pro™), Grape seed extracts (see Beyond Chelation Improved®, Prostate-Pro™, Resveratrol-Pro™), Green tea extracts (see DietPro™, Nexiclear®, Resveratrol-Pro™, ProstatePro™), Growth hormone (see HGH), Gymnena sylvestre extracts (see Diet-Pro™)

NEW: Neurontin® 100x 300mg capsules retail $140 IAS price $129.99 - Item Code: 875

Gamibetal® 20x 500mg tablets retail $39 IAS price $32.49 - Item Code: 402

Galantamine (Reminyl®)

Reminyl® 28x 8mg tablets retail $99 IAS price $89.99 - Item Code: 611

36

Gamalate B6®

NEW: Advanced Cellular Glutathione® 2 oz. spray retail $40 IAS price $39.99 - Item Code: 832

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com


Hair-Pro™

NEW: Hair-Pro™ 2 oz. spray bottle retail $180 IAS price $169.99 - Item Code: 765

Hawthorne Berry (crataegus, see Beyond Chelation Improved®, Neo40®), Heart rate measurement (see Bio-CLIP™, Bio-CUFF™)

HemaGel®

NEW: HemaGel® 5 gram tube cream retail $19 IAS price $17.49 - Item Code: 820

HGH (human growth hormone, somatropin, see IGF-1, Sermorelin, Beyond GHS®, GABOB, GHRP2, GHRP6), Humatrope® (see HGH), Hyaluronic acid (see Crème-Pro™ Protector, Gengigel®, Hair-Pro™, Hy-Col™)

HRT Plus®(pueraria mirifica) HRT Plus® 60 tablets retail $50 IAS price $49.99 - Item Code: 496

Hy-Col® (collagen)

Hy-Col™ 120x 250mg capsules retail $35 IAS price $29.99 - Item Code: 553

Hydergine (ergoloid mesylate) Hydergine® 30x 4.5mg tablets retail $34 IAS price $27.49 - Item Code: 32

Hydergine® 40mg 40ml liquid bottle retail $24 IAS price $19.99 - Item Code: 31

Hydrocortisone

Hydro-Pro® 100x 5mg capsules retail $29 IAS price $24.99 - Item Code: 760

Hydrogen (see Active H-Minus®), Hydrogen peroxide (see Nexiclear®)

Idebenone (also see Crème-Pro™ Protector)

Idebenone 60x 30mg capsules retail $29 IAS price $24.99 - Item Code: 492

IGF-1 (insulin like growth factor, see Hair-Pro™), Indol-3-Carbinol (I3C, see DIM)

Injection packs

Intramuscular kit 20x pack retail $25 IAS price $21.99 - Item Code: 439 Subcutaneous kit 20x pack retail $25 IAS price $21.99 - Item Code: 438

Inosine (see Beyond GHS®), Inositol (see Beyond Chelation Improved®), Iodide (see ACF228™), Iodine (see ACF228™, Beyond Chelation Improved®), Isoflavonoids (see HRT Plus®), Ixel® (see milnacipran), Jerusalem artichoke (see Beyond Fiber®)

Joint-Pro™

Joint Pro™ 180 capsules retail $50 IAS price $44.99 - Item Code: 432

Jumex® (see deprenyl), Ketoconazole (see Nizoral®), Kohki leaf extract (see Prostate-Pro™)

Krill

Krill 60x 500mg gel capsules retail $45 IAS price $39.99 - Item Code: 584

Laetrile (amygdalin; VitaB17®) B17 cream 50ml 1% retail $89 IAS price $79.99 - Item Code: 763

L-arginine (see arginine)

L-carnosine (also see ACF228™; CanC™; Can-C Plus™; Cardio-Pro™)

Carnosine 60x 250mg capsules retail $29 IAS price $24.49 - Item Code: 784 L-citrulline (see Neo40®), L-cysteine (see Nanogen® conditioner), Lecithin (see Crème-Pro™ Cellulite), L-histidine (see Can-C Plus™), Lemon grass (see Dr Gordon’s Organic Greens®), Licorice (see Beyond GHS®, Digestif®), Lipoic acid (alpha version see Beyond Chelation Improved®; R-version see ATP-Boost™), Lithium orotate (see Cardio-Pro™, Lithium-Pro™)

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37


Lithium-Pro™

Lithium-Pro™ 60 capsules retail $25 IAS price $19.99 - Item Code: 717

L-methione (see ACF228™; Can-C Plus™), L-proline (see Nitric-Pro™), Lucidril® (see centrophenoxine), Lumbrokinase (see Boluoke®), Lupine extract (see Nanogen® serum)

L-tryptophan

L-tryptophan 50x 500mg capsules retail $20 IAS price $14.99 - Item Code: 666

Lycopene (see DIM-Pro™; Prostate-Pro™), Lysine (see Nitric-Pro™)

Maca® (Longevity Maca®; lepidium meyenii walp)

Metforal®)

Dianben® 50x 850mg tablets retail $25 IAS price $22.99 - Item Code: 382 Metforal® 50x 500mg tablets retail $24 IAS price $19.99 - Item Code: 42

Methione (see Beyond Chelation Improved®)

Milnacipran (Ixel®; Savella®) Ixel® 56x 50mg tablets retail $75 IAS price $69.99 - Item Code: 400

Minerals (general, see Quinton®), Minoxidil (see MinSaw™)

MinSaw™

NEW: Longevity Maca® 175 grams powder retail $45 IAS price $39.99 - Item Code: 359

MinSaw™ 30ml bottle topical liquid retail $45 IAS price $39.99 - Item Code: 728

Magnesium (see Andro-Pro™, Beyond Chelation Improved®, Bone-Pro™, Digestif®, Gamalate B6®, Nitric-Pro™), Malic acid (see Beyond Chelation Improved®), Manganese (see Beyond Chelation Improved®, Bone-Pro™), Marigold (see Nexiclear®), Mastic (see Digestif®), Meclofenoxane (see centrophenoxine)

Miroestrol (see HRT Plus®), Mito-Pro™ (see ATP-Boost™)

Melatonin (MZS™; Melatonin Zn Se®)

Modafinil (also see adrafinil)

MZS™ 60x 3mg tablets retail $30 IAS price $19.99 - Item Code: 701

Moclobemide (Manerix®/ Moclamine®)

Moclamine® 30x 150mg tablets retail $34 IAS price $24.99 - Item Code: 39

Alertec® 30x 100mg tablets retail $180 IAS price $159.99

UK can order in Pounds Sterling at: www.melatoninznse.com

Modiodal® 30x 100mg tablets retail $150 IAS price $129.99

Melon extracts (see Diet-Pro™)

Provigil® 30x 100mg tablets retail $190 IAS price $174.99

Memantine (Namenda®; Ebixa®)

Note: This product is only available via www.modafinil-store.com and payable via eChecks or bank wire only.

Melanocyte stimulating hormone (see Melanotan II)

Molybdenum (see Beyond Chelation Improved®, Joint-Pro™), MSM (methylsulfonomethane, see Beyond Chelation Improved®, Bio-En’R-Gy®, Nitric-Pro™), N-acetylcarnosine (see Can-C™), N-acetylcysteine (see ACF228™, Can-C™ Plus),

NEW: Memantine-Pro™ 42x 10mg capsules retail $115 IAS price $99.49 - Item Code: 727

38

Metformin (Glucophage®;

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NADH (Nicotinamide adenine dinucleotide, see Crème-Pro™ Moisturizer, PQQ)

Naltrexone (Navcol®)

Naltrex-Pro™ 30x 4.5mg capsules retail $60 IAS price $54.99 - Item Code: 637

Nanogen® conditioner

Nanogen® 240ml bottle conditioner retail $25 IAS price $21.49 - Item Code: 752

Nanogen® hydrator

NEW: Nanogen® 100ml spray hydrator retail $24 IAS price $19.99 - Item Code: 809

Nanogen® serum

NEW: Nanogen® 30ml serum dropper retail $49 IAS price $47.49 - Item Code: 822

Nanogen® shampoo

Nitric-Pro™

Nitric-Pro™ 225 grams powder retail $40 IAS price $35.99 - Item Code: 792

Nizoral® shampoo (2% ketoconazole) Nizoral® 60ml bottle shampoo retail $15 IAS price $12.49 - Item Code: 437

Nordihydroguaiaretic acid (NDGA, see ACF228™, Digestif®), Norditropin® (see HGH), Oat grass (see Dr Gordon’s Organic Greens®), Omega 3 (see Beyond Chelation Improved®, krill), Omega 6 (linoleic acid, GLA, see Beyond Chelation Improved®, krill), Omega 9 (oleic acid, see Beyond Chelation Improved®, krill), Oxythiocynate (OCSN, thiocynates, see 1st Line™)

Oxytocin (Oxy-Pro™)

Oxytocin 24x 20 IU sublingual troches retail $85 IAS price $79.99 - Item Code: 660

Nanogen® 240ml bottle shampoo retail $22 IAS price $19.49 - Item Code: 751

NEW: Oxy-Pro® 5ml 500 IU nasal spray retail $60 IAS price $54.99 - Item Code: 823

Needles (see injection packs), Neurontin® (see Gabapentin), Nettle root extract (see ProstatePro™)

Neo40 Daily® 30x lozenges retail $60 IAS price $59.99 - Item Code: 790

PABA (para-aminobenzoic acid, see Beyond Chelation Improved®, Gerovital®), Palladium (see Cardio-Pro™), Palmitate (see Beyond Chelation Improved®), Pancreatin (see Wobenzym®), Panthenol (pantothenic acid, see vitamin B5), Papain (see Beyond Chelation Improved®, Wobenzym®)

Nettle root extract (see Prostate-Pro™)

Penicillin (Penilevel®)

Neo40®

Penilevel® 30x 250mg sachets powder retail $35 IAS price $29.99 - Item Code: 206

Nexiclear®

NEW: Mask, pads & spray kit retail $60 IAS price $59.99 - Item Code: 834

Pentavita (see Nanogen®)

Niacin (nicotinate, niacinamide, see vitamin B3)

Peptide Bioregulators

Nicergoline (Sermion®)

Sermion® 50x 10mg tablets retail $49 IAS price $44.99 - Item Code: 489

Nitric Oxide Saliva Test Strips Neo40® 25 saliva strips $25 IAS price $24.99 Item Code: 791

NEW: Adrenals (Glandokort®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 853 NEW: Blood vessels (Ventfort®) 20x 200mg capsules retail $90 IAS price $79.99 Item Code: 868 NEW: Brain (Cerluten®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 867

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39


Peptide Bioregulators NEW: Eyesight (Visoluten®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 856

PulmoLife®1 Spirometer + 4 tubes retail $155 IAS price $139.99 - Item Code: 781

NEW: Kidneys (Pielotaks®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 869

PulmoLife®25 additional tubes retail $25 IAS price $19.99 - Item Code: 782

NEW: Prostate (Libidon®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 854

Pramiracetam

NEW: Testes (Testoluten®) 20 x 200mg capsules retail $90 IAS price $79.99 - Item Code: 855

Phenytoin (Dilantin®, Epanutin®)

Pramiracetam 40x 300mg tablets retail $60 IAS price $49.99 - Item Code: 451

Prasterone (see DHEA)

Phen-Pro™ 28x 25mg capsules retail $20 IAS price $17.99 - Item Code: 786

Pregnenolone

Phosphatidylcholine (see Beyond Chelation Improved®, Crème-Pro™ Cellulite), Phosphatidylserine (see Beyond Chelation Improved®), Phospholipids (see krill), Phosphorous (see Bone-Pro™, Nitric-Pro™)

Procaine (Novocain®, see Gerovital®, Crème-Pro™ Moisturizer)

Picamilone

Progesterone 50ml 2.5 grams cream retail $35 IAS price $29.99 - Item Code: 789

Picamilone 60x 50mg tablets retail $25 IAS price $17.49 - Item Code: 184

Pimagidine (see aminoguanidine)

Piracetam (Nootropil®; also see Anacervix®)

Nootropil® 20 grams 100ml liquid retail $24 IAS price $19.99 - Item Code: 50 Nootropil® 60x 800mg tablets retail $29 IAS price $27.49 - Item Code: 205 Polyphenols (see grape seed extract), Pomegranate extracts (see Andro-Pro™), Potassium (see Beyond Chelation Improved®, Gerovital®), Potassium iodide (see ACF228™)

PQQ (pyroloquinoline quinone)

NEW: PQQ-Pro™ 30x 20mg capsules retail $40 IAS price $35.99 - Item Code: 837

Pueraria mirifica (see HRT Plus®)

40

PulmoLife®

Pregnenolone 50x 100mg capsules retail $25 IAS price $19.99 - Item Code: 335

Progesterone

Propranolol (Inderal®)

Inderal® 30x 40mg tablets retail $19 IAS price $14.99 - Item Code: 34

Prostate-Pro™

Prostate-Pro™ 90x 500mg tablets retail $55 IAS price $49.49 - Item Code: 433

Pueraria mirifica (see HRT Plus®), Pygeum africanum (see Nanogen®, Prostate-Pro™)

Pyridoxamine

Pyri Pro 60x 50mg tablets retail $35 IAS price $29.99 - Item Code: 449

Pyritinol

Cerbon 6® 60x 100mg tablets retail $25 IAS price $19.99 - Item Code: 167

Pyroloquinoline quinone (see PQQ), Quercetin (see Digestif®, Resveratrol-Pro™)

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Quinton®

Isotonic® 24 oral ampoules retail $45 IAS price $39.99 - Item Code: 681 Hypertonic® 24 oral ampoules retail $45 IAS price $39.99 - Item Code: 682

Rasagiline (see Azilect®)

Reboxetine (Edronax®; Davedax®) Edronax® 60x 4mg tablets retail $60 IAS price $59.99 - Item Code: 22

Red algae (carrageenan, see Beyond Chelation Improved®), Red yeast (see Beyond Chelation Improved®), Reminyl® (see Galantamine), Resveratrol (see ACF228™, Beyond Chelation Improved®, Cardio-Pro™, Crème-Pro™ Protector, MinSaw™, Resveratrol-Pro™)

Resveratrol-Pro™

Resveratrol-Pro™ 60 capsules retail $30 IAS price $24.99 - Item Code: 647

Retin-A®

Retirides® 30ml 0.025% cream retail $40 IAS price $32.49 - Item Code: 254 Retirides® 30ml 0.050% cream retail $45 IAS price $39.99 - Item Code: 764 Retirides® 30ml 0.100% cream retail $60 IAS price $44.99 - Item Code: 74 Retin-A® 20ml 0.100% micro-gel retail $75 IAS price $69.99 - Item Code: 744

Retinolic acid (tretinoin, see MinSaw™, Retin-A®), Ribonucleic acids (RNA, see Cerebrolysin®, NeyDent®, NeyGeront®), Ribose (see Bio-En’R-Gy®), Rice bran husks (see Beyond Fiber®), R-lipoic acid (see ATP-Boost™)

Salicylic acid (see BEC5 Curaderm®, Nanogen® shampoo, Nexiclear®)

SAMe (S-Adenosyl-L-Methionine; SAMYR®)

SAMYR® 20x 400mg enteric-coated tablets retail $69 IAS price $59.99 - Item Code: 231 Saw palmetto (Serena repens, see MinSaw™; Nanogen®)

Scalproller®

Scalproller® 0.3mm roller kit retail $79 IAS price $69.99 - Item Code: 762

Selepryl® (see deprenyl), Selegiline (see deprenyl), Selenium (see ACF228™, Beyond Chelation Improved®, Detox-Pro™, MZS™, Prostate-Pro™, Thym-Uvocal®)

Sermorelin

Sermo-Pro® 30ml/ 30mg liquid bottle retail $225 IAS price $199.99 Item Code: 714

Shave grass (see Dr Gordon’s Organic Greens®), Silicon/ Silica (see Beyond Chelation Improved®; Bone-Pro™, Nanogen™, Wobenzym®)

Silver protein (ACS®)

Advanced Cellular Silver 200® 2 oz. spray retail $35 IAS price $34.99 - Item Code: 574

Soapwort (see Nexiclear®), Solasodine glycosides (see BEC5 Curaderm®), Somatomedin C (see IGF-1), Somatropin (see HGH), Spirulina (see Dr Gordon’s Organic Greens®)

Stablon® (tianeptine)

Stablon@ 60x 12.5mg tablets retail $69 IAS price $59.99 - Item Code: 748

Roxithromycin (Rulid®)

Rulid® 10x 150mg tablets retail $25 IAS price $22.49 - Item Code: 635

Rutin (see Wobenzym®), Saizen® (see HGH), Salacia reticulata extracts (see Diet-Pro™),

Stevia (see Dr Gordon’s Organic Greens®), Strontium (see Bone-Pro™), Succinic acid (DMSA, see Heavy Detox®), Superoxide dismutase (SOD, see Nanogen® serum), Syringes (see injection packs)

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41


TA65®

TA65® 30 capsules IAS price $218.99 - Item Code: 755 TA65® 90 capsules IAS price $599.99 - Item Code: 754

Tamanu

Tamanu 50ml bottle oil retail $25 IAS price $21.99 - Item Code: 724

Telomeres/ telomerase (see TA65®), Temple viper venom (synthetic, see Crème-Pro™ Smoother)

Tetracycline (Ambramicina®)

Ambramicina® 16x 250mg tablets retail $29 IAS price $19.99 - Item Code: 143

Thymus (Thym-Uvocal®)

Thym-Uvocal® 90x 200mg capsules retail $115 IAS price $99.99 - Item Code: 691

Thyroid (Armour®; Synthroid®) Armour® 100x 15mg tablets retail $49 IAS price $47.99 - Item Code: 411 Armour® 100x 30mg tablets retail $59 IAS price $54.99 - Item Code: 468

Westhroid® 100x 15mg tablets retail $39 IAS price $34.99 - Item Code: 613 Westhroid ® 100x 30mg tablets retail $49 IAS price $37.99 - Item Code: 324 Westhroid ® 100x 45mg tablets retail $54 IAS price $44.99 - Item Code: 324 Westhroid ® 100x 60mg tablets retail $59 IAS price $49.99 - Item Code: 323 Westhroid ® 100x 120mg tablets retail $89 IAS price $79.99 - Item Code: 460 Our synthetic thyroids include:

NEW: IBSA® 25 tablets (21.4mcg T3 and 74mcg T4) retail $35 IAS price $29.99 - Item Code: 778 Titre® (T3) 50x 20mcg tablets retail $35 IAS price $29.99 - Item Code: 314 Tiromel® (T3) 100x 25 mcg tablets retail $45 IAS price $39.99 - Item Code: 811 Eutirox® (T4) 84x 100mcg tablets retail $25 IAS price $21.99 - Item Code: 662

Armour® 100x 90mg tablets retail $89 IAS price $84.99 - Item Code: 594

Thyrotropin releasing hormone (see TRH), TMG (trimethylglycine, betaine, see Beyond Chelation Improved®, Bio-En’R-Gy®, Joint-Pro™), Tocotrienols (see Beyond Chelation Improved®), Tribulus terrestris (see Andro-Pro™, Beyond GHS®, Vigor-Pro™)

Armour® 100x 120mg tablets retail $109 IAS price $99.99 - Item Code: 410

TRH (Abaris™)

Armour® 100x 60mg tablets retail $69 IAS price $64.99 - Item Code: 7

ERFA 100x 30mg tablets retail $45 IAS price $39.99 - Item Code: 0736 NEW: ERFA 500x 30mg tablets retail $150 IAS price $129.99 - Item Code: 876

NEW: Abaris™ 20 x 5mg sublingual tablets retail $250 IAS price $199.99 - Item Code: 793

ERFA 100x 60mg tablets retail $60 IAS price $54.99 - Item Code: 737

Trypsin (see Wobenzym®), TRX (see Hair-Pro™), Ubiquinol (see CoQ10), Ubiquinone (see CoQ10), Urea (see BEC5 Curaderm®), Urtica dioica (see Nanogen®)

NEW: ERFA 500x 60mg tablets retail $195 IAS price $179.99 - Item Code: 877

Valdoxan® (agomelatine)

ERFA 100x 125mg tablets retail $95 IAS price $89.99 - Item Code: 738 42

NEW: ERFA 500x 125mg tablets retail $260 IAS price $239.99 - Item Code: 878

Valdoxan® 28x 25mg tablets retail $149 IAS price $132.49 - Item Code: 690

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Vasopressin (also see desmopressin)

NEW: Vaso-Pro® 5 ml 500 IU nasal-spray retail $69 IAS price $64.49 - Item Code: 838

Vigor-Pro™), Vitamin D3 (cholecalciferol, see Beyond Chelation Improved®, Bone-Pro™, D3Pro™), Vitamin C (ascorbic acid, see Beyond Chelation Improved®, Bio-En’R-Gy C®, Bone-Pro™, Digestif®; MinSaw™, Neo40®, Nitric-Pro™)

Vanadium (see Beyond Chelation Improved, Diet Pro), VEGF (see Hair-Pro™, Nanogen® conditioner, Nanogen™ hydrator, Nanogen® serum, Nanogen® shampoo)

Vitamin C test strips (Vitacheck-C®)

Venlafaxine (Efexor®)

Vitamin E (tocopherols, see Beyond Chelation Improved®, Can-C Plus™, Nitric-Pro™, ProstatePro™, Resveratrol-Pro™, Vigor-Pro™), Vitamin K1 (phylloquinone, see Bone-Pro™), Vitamin K2 (menatretrenone, see Beyond Chelation Improved®, Bone-Pro™), Wheat grass (see Dr Gordon’s Organic Greens®)

Venlafaxine 60x 37.5mg tablets retail $45 IAS price $37.49 - Item Code: 488

Viagra® (sildenafil)

Viagra® 4x 100mg tablets retail $88 IAS price $79.99 - Item Code: 90

NEW: Vitacheck-C® 50 strips retail $15 IAS price $12.99 - Item Code: 774

Wobenzym-N®

Vigor-Pro™

Vigor-Pro™ 90 capsules retail $25 IAS price $21.49 - Item Code: 761

Wobenzym® 200 tablets retail $70 IAS price $69.99 - Item Code: 381

Wormwood (see artemisinin)

Vincamine (see Anacervix®)

Vinpocetine (Intelectol®)

Intelectol® 50x 5mg tablets retail $19 IAS price $15.99 - Item Code: 91

Vitamin A (beta carotene, palmitate, see Beyond Chelation Improved®), Vitamin B1 (thiamine, see Beyond Chelation Improved®, Nitric-Pro™), Vitamin B1 (see benfotiamine), Vitamin B2 (riboflavin, see Beyond Chelation Improved®, Nitric-Pro™, Vigor-Pro™), Vitamin B3 (niacin, niacinamide, see Beyond Chelation Improved®, Crème-Pro™ Cellulite, Nanogen® hydrator, Nanogen® serum, Nitric-Pro™, picamilone; Vigor-Pro™, Xan-Pro™), Vitamin B5 (panthenol, pantothenic acid, see Beyond Chelation Improved®, Nitric-Pro™, Vigor-Pro™), Vitamin B6 (pyridoxine, see ACF228™, Andro-Pro™, Beyond B12®, Beyond Chelation Improved®, Gamalate B6®; Joint-Pro™, HRT Plus®, Nanogen®; Nitric-Pro™, Vigor-Pro™), Vitamin B6 (see pyridoxamine), Vitamin B12 (cobalamin, see Beyond B12®, Beyond Chelation Improved®, Crème-Pro™ Moisturizer, Joint-Pro™, Lithium-Pro™, Neo40®,

Xan-Pro® (xanthinol nicotinate) Xan-Pro® 50x 150mg tablets retail $20 IAS price $17.49 - Item Code: 552

Yohimbe (see Vigor-Pro™)

Yohimbine (also see Crème-Pro™ Cellulite, Vigor-Pro™)

Plain Prowess® 100x 5mg tablets retail $59 IAS price $49.99 - Item Code: 94

Zeolite (also see Nexiclear®) ZeoGold® 30 capsules retail $60 IAS price $59.99 - Item Code: 684

NEW: Advanced Cellular Zeolite®2 oz. spray retail $40 IAS price $39.99 - Item Code: 833 Zinc (see Andro-Pro™, Beyond Chelation Improved®, Can-C Plus™, MZS™, Nanogen® shampoo, Thym-Uvocal®)

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43


Help IAS Attract A Wider Audience We’re proud of Antiaging Systems and the hundreds of thousands of people we have helped take responsibility for the destiny of their own health over the last 20 years, we believe that’s something to shout about. If you agree and would like to help us spread the word we run a number of business associate programs for helping to develop business contacts and markets, whether as an aďŹƒliate referral, wholesale or drop ship distributor there is a program to suit you.

If you want to work with us in taking these products to a wider audience email us today at associates@antiaging-systems.com 44

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com


Condition cross-reference list

Adaptogens

This cross-reference list highlights individual products that have been used to treat & prevent various aging disorders. Note: It does not mean that all these products are synergistic together.

ADHD (ADD, attention deficit disorder, see mental

HRT Plus®, maca, Quinton®

Addison’s disease

Aldosterone, Peptide Bioregulator- Glandokort®

stimulants)

Adrenal fatigue

Adrenal-Pro™, aldosterone, hydrocortisone, Peptide Bioregulator - Glandokort®

AGE (Advanced Glycated End Products, cross linking of proteins)

ACF228™, aminoguanidine, Can-C Plus™, Cardio-Pro™, L-carnosine, metformin, pyridoxamine

Age Related Macular Degeneration (see eyesight)

Age Related Mental Decline (see cognitive) Aids (see HIV) Alcoholism (also see compulsive disorders) 5HTP, L-tryptophan, memantine

Allergies

Bio-En’R-Gy C®, Joint-Pro™, pregnenolone, ThymUvocal®, Wobenzym®

ALS (amyotrophic lateral sclerosis, see Lou Gehrig’s disease)

Alzheimer’s (see senile dementia) Aminoacids (including di-peptides)

5HTP, ACF228™, ATP-Boost™, Beyond GHS®, CardioPro™, L-carnosine, L-tryptophan, Nitric-Pro

Anabolic (see growth hormone & testosterone) Anginas (see heart, arterial & blood) Animal use

Can-C™ eye-drops, deprenyl, L-tryptophan

Antiaging (as impacting on a particular theory of aging)

Aminoguanidine (glycosylation), centrophenoxine (membrane), hydergine (mitochondrial), L-carnosine (Hayflick), melatonin (rotational), metformin (neuroendocrine), resveratrol (calorie restriction), ACF228™ (free radical), TA65 (telomeres)

Anti-biotics (also see influenzas & infections) Ciproxin, doxycycline, penicillin, roxithromycin, tetracycline

45


Anti-depressants (also see depression & well being)

Lithium-Pro™, milnacipran (Ixel®), moclobemide (Manerix®), Paxil®, reboxetine (Edronax®), Stablon®, Valdoxan® (agomelatine), venlafaxine (Efexor®)

Anti-inflammatory (see inflammation) Anti-oxidants (free radical scavengers)

ACF228™, Active H-minus®, ATP-Boost™, Bio-En’RGy®, glutathione, idebenone, melatonin, pyritinol

Anxiety (see stress)

Cataplexy (sudden fatigue) Adrafinil, modafinil, picamilone

Cataract (also see eyesight) Can-C™, Can-C Plus™

Chelation agents (removing heavy metals, also see detox)

Beyond Chelation Improved®, Beyond Fiber®, Bio-En’RGy C®, centrophenoxine, Detox-Pro™, Dr. Gordon’s organic greens®, L-carnosine, zeolite

ARMD (see eyesight)

Cholesterol (see blood disorders)

Aromatase inhibitors

Crohn’s disease

Arterial (See heart, arterial & blood)

Chronic fatigue syndrome (see mental

Arimidex®, Beyond HRT®, DIM-Pro™, progesterone

Arthritis (rheumatoid & osteo)

Gerovital-H3®, Hy-Col™, Joint-Pro™, krill, pregnenolone, pyritinol, SAMe, Thym-Uvocal®, Wobenzym®

Asthma (see Allergies) Autism (also see chelation agents) Oxytocin, piracetam

At-home test kits (also see health diagnostics) Bio-CUFF™, Bio-CLIP™, Nitric Oxide saliva strips, PulmoLife®, vitamin C urine strips

Bell’s palsy

Beyond B12®

Beta blockers Propranolol

Blood disorders (see heart, arterial & blood) Blood pressure

Neo40®, Nitric-Pro™, oxytocin, propranolol, vinpocetine

Bone problems (also see joints & arthritis) Andro-Pro™, Bone-Pro™, Esnatri™, Hy-Col™, progesterone, SAMe, thyroid

Breathing (see Lungs) Cancer (also see anti-oxidants & radiation)

1st Line™, Arimidex®, artemisinin, BEC5® Curaderm, Beyond HRT®, Bio-En’R-Gy®, bromocriptine, CurcuminSR™, D3-Pro™, DIM-Pro™, HRT Plus®, laetrile, melatonin, metformin, naltrexone, progesterone, Resveratrol-Pro™, Thym-Uvocal®, TRH, Wobenzym®

46

Cardiovascular (see heart & arterial disorders)

Naltrexone

stimulants & physical energy improvement)

Cognitive (also see memory & senile dementias) Alertness: Adrafinil, modafinil Creativity: Aniracetam, piracetam, pramiracetam Concentration: Phosphatidylserine Focus: Deprenyl, desmopressin, vasopressin Energy: ATP-Boost™, centrophenoxine, picamilone General support: Gerovital-H3®, vinpocetine Intelligence: Hydergine Work load: Hydergine, thyroid

Compulsive disorder treatment (also see alcoholism)

5HTP, Gamalate-B6®, L-tryptophan, picamilone

Cortisol alteration (also see stress)

Aldosterone, fludrocortisone, Gamibetal®, Gamalate B6®, hydrocortisone, Peptide Bioregulator - Glandokort®, Gerovital-H3®, phenytoin

Cross linking (see advanced glycated end products)

Deep vein thrombosis (see frequent fliers) Dental (see teeth & gums) Depression (also see well-being & antidepressants)

5HTP, aniracetam, ATP Boost™, ATP-Boost™, D3Pro™, deprenyl, Gerovital-H3®, Lithium-Pro™, L-tryptophan, milnacipran, Geront®, picamilone, piracetam, pramiracetam, pregnenolone, SAMe, Thym-Uvocal®, thyroid, Vigor-Pro™

Detox (also see chelation agents)

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com


Artemisinin, Bio-En-R-Gy®, Beyond Clean®, Beyond Fiber®, DIM-Pro™, Detox-Pro™, Dr. Gordon’s organic greens®, zeolite

DHT alteration (dihydrotestosterone)

Dutasteride, finasteride, Hair-Pro™, MinSaw™, Nanogen’s®, Peptide Bioregulator - Libidon®, progesterone

Diabetes

Acarbose, aminoguanidine, ATP-Boost™, benfotiamine, Diet-Pro™, krill, L-carnosine, metformin, Nitric-Pro™, pyridoxamine, TRH, thyroid

ARMD: MZS™ Cataracts: Can-C™, Can-C™ Plus Contact lenses: Can-C™ Dry eyes: Can-C™ General support: Aminoguanidine, Peptide Bioregulator Visoluten®, vinpocetine Glaucoma: Can-C™ Retinal: MZS™, nicergoline, picamilone

Excitotoxins (reduction)

Carnosine, deprenyl, idebenone, L-carnosine, LithiumPro™, memantine

Fertility

Dieting (See weight loss)

Melatonin, metformin, TRH

Digestive issues

Beyond Fiber®, Digestif®, Dr. Gordon’s organic greens®

DNA support (also see telomeres)

CoQ10, D3-Pro™, krill, L-carnosine, NeyGeront®, Peptide Bioregulators, PQQ, Resveratrol-Pro, TA65®

Down’s syndrome

Fibromyalgia (also see physical energy & mental stimulants & pain relief )

1st Line, milnacipran, naltrexone, oxytocin

First Aid cabinet

1st Line™, HemaGel®, silver protein

Free radical scavengers (see anti-oxidants)

Melatonin, piracetam

Dr. Gordon’s recommend products

Frequent fliers

Dr. Pierpaoli’s recommend products

Gastrointestinal (see digestive)

Beyond B12®, Beyond Chelation Improved®, Beyond Clean®, Beyond Fiber®, Beyond GHS®, Bio En’R-Gy C®, Dr Gordon’s Organic Greens®, HRT Plus®, maca, silver protein, zeolite Melatonin, TRH

Dr. Wright’s recommend products Esnatri, cobalt chloride, progesterone

Energy improvement (see physical energy & mental stimulants)

1st Line, artemisinin, Cardio-Pro™, Gamalate-B6®, Gamibetal®, L-tryptophan, melatonin, Neo40®, NitricPro™, picamilone, piracetam, pregnenolone, ResveratrolPro™, silver protein

Glaucoma (see eyesight) Glucose control (see diabetes) Glycation prevention (see AGE) Gout

Colchicine

Enzymes

Growth hormone (improvement)

Boluoke®, Wobenzym®

Epilepsy

Gamalate®, Gamibetal®, phenytoin

Erectile dysfunction (also see sex-libido & premature ejaculation)

Andro-Pro™, cabergoline, Cialis®, Neo40®, Nitric-Pro™, oxytocin, Viagra®, Vigor-Pro™, yohimbine

Estrogen alteration (both increases & decreases)

Arimidex®, cobalt chloride, DIM-Pro™, Esnatri™, HRT Plus®, progesterone

Eyesight (also see cataract, ARMD & glaucoma)

Beyond GHS®, bromocriptine, deprenyl, Gamalate®, Gamibetal®, hydergine, Neo40®, Nitric-Pro™, Sermorelin, Thym-Uvocal®, thyroid

Hemorrhoids Nitric-Pro™

Hair improvement

Dercos®, dutasteride, finasteride, Gerovital-H3®, HairPro™, krill, MinSaw™, Nanogen’s, Nitric-Pro™, Nizoral®

Headaches (see migraines) Heath diagnostics (see at home test kits) Hearing disorders

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

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Aldosterone, Anacervix®, fludrocortisone, nicergoline, picamilone, vinpocetine

Heart, arterial & blood (includes blood markers)

Arteries (hard): Aminoguanidine, Bio-CLIP™, BioCUFF™, Cardio-Pro™, L-Carnosine, Resveratrol-Pro™ Blood pressure (high): Neo40®, Nitric-Pro™, Propranolol, vinpocetine Cholesterol (high): Beyond B12®, Beyond Fiber™, CoQ10, TRH, Xan-Pro™ Dilation (nitric-oxide): Neo40®, Nitric-Pro™ Fibrinogen: CurcuminSR™, TRH, Wobenzym® General support: Cardio-Pro™, CoQ10, krill, PQQ, vinpocetine, Wobenzym® Glucose (high): Acarbose, metformin, TRH Glycated end-products: Aminoguanidine, metformin Heart pulse (irregular): ATP-Boost™, Bio En’R-Gy C®, thyroid Heavy metals (chelate): Beyond Chelation Improved®, Beyond Fiber®, Bio En’R-Gy C®, Heavy Detox™ Homocysteine: Beyond B12®, Beyond Chelation Improved®, Bio En’R-Gy C®, TRH Lipofuscin: Centrophenoxine Plaques (clots): Boluoke® Triglycerides: Bio En’R-Gy C®, CurcuminSR™, krill, TRH

Herpes (also see anti-biotics)

1st Line™, ACF228™, silver protein, Wobenzym®

HIV (also see immune system improvement) 1st Line™, melatonin, naltrexone, Thym-Uvocal®

HGH (see growth hormone) Homocysteine (see blood disorders) Hormones (includes hormonal support supplements)

Bio-identical: Aldosterone, Esnatri™, melatonin, oxytocin, pregnenolone, progesterone, TRH Natural (animal): Adrenal-Pro™, Armour® thyroid, ERFA® thyroid, Nature® thyroid, Thym-Uvocal®, vasopressin, West® thyroid Synthetic: Desmopressin, Eutirox® thyroid, fludrocortisone, hydrocortisone, IBSA® thyroid, Tiromel® thyroid, Titre® thyroid Supporting agents: Andro-Pro™, Peptide Bioregulator Glandokort®, Peptide Bioregulator - Libidon®, Peptide Bioregulator - Testoluten®, Cobalt chloride, DIM-Pro™, Vigor-Pro™

HRT (hormone replacement therapy for women) Cobalt chloride, Esnatri™, HRT Plus®, melatonin, progesterone

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Human growth hormone (see growth hormone)

Hydrogen

Active H-minus®

Hypertension (see blood pressure) Immune system improvement (also see infections)

1st Line™, ATP-Boost™, Beyond B12®, L-carnosine, maca, melatonin, NeyGeront®, pyritinol, Resveratrol-Pro™, Thym-Uvocal®, thyroid

Infections (also see immune system

improvement, anti-biotics & influenzas)

1st Line™, artemisinin, fluconazole, silver protein, Wobenzym®

Inflammation (reduction)

Beyond Chelation Improved®, Bio-En’R-Gy®, Boluoke®, CurcuminSR™, Digestif®, Dr. Gordon’s organic greens®, krill, maca, pregnenolone, Thym-Uvocal®, Wobenzym®

Influenzas (also see anti-biotics, infections & immune system improvement) 1st Line™, Relenza®

Insulin & glucose control (see diabetes) Intestinal flora (see probiotics) Joints (also see bones & arthritis)

Boluoke®, Hy-Col™, Joint-Pro™, krill, pregnenolone, SAMe, Thym-Uvocal®, Wobenzym®

Kidney disorders (also see infections) Aminoguanidine, SAMe, TRH

Learning (also see memory & mental stimulants) Aniracetam, desmopressin, hydergine, piracetam, pramiracetam, vasopressin

Libido (see sex) Lipids (see blood disorders) Liver disorders (also see infections)

Idebenone, pregnenolone, SAMe, silver protein

Longevity enhancement (significant increases seen in animal studies)

Centrophenoxine, deprenyl, Desmopressin, melatonin

Lou Gehrig (ALS) Naltrexone, TRH

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com


Lungs

ACF228™ Breathe-Easy, Centrophenoxine, Nitric-Pro™, PulmoLife®

Oral health care (see teeth & gums) Osteoporosis (see bone problems) Pain relief

Lupus

ATP-Boost™, Gerovital-H3®, memantine, milnacipran, nicergoline, oxytocin, Wobenzym®

Milnacipran, naltrexone

Lyme’s

Parasites (see infections)

1st Line™, silver protein

Macular degeneration (see ARMD & eyesight)

Parkinson (see senile dementia)

Malaria (also see anti-biotics)

Peptides

Peptide Bioregulator - Glandokort®, Peptide Bioregulator - Libidon®, Peptide Bioregulator - Testoluten®, Peptide Bioregulator - Visoluten®

Artemisinin

Menopause (see HRT)

Pets (see Animal use)

Mental stimulants

Adrafinil, aniracetam, centrophenoxine, deprenyl, desmopressin, modafinil, nicergoline, picamilone, piracetam, pramiracetam, vasopressin, Xan-Pro™

Memory (also see cognitive & senile dementia) General support: Krill, vinpocetine Imprinting (for later recall): Desmopressin, vasopressin Medium-long term: Hydergine, phosphatidylserine Short term: Aniracetam, piracetam, pramiracetam Speed of recall: Centrophenoxine, pyritinol

Methylation (conversion of one chemical into another inside the body)

ATP-Boost™, Beyond B12® Bio-En’R-Gy®, Boluoke®, SAMe, Wobenzym®, Xan-Pro™

Migraines (also see pain relief )

Beyond B12®, nicergoline, memantine, picamilone, Quinton®

Minerals (including trace- also see vitamins)

Beyond Chelation Improved®, Cardio-Pro™, Quinton®

Mitochondrial support

ATP-Boost™, CoQ10, deprenyl, glutathione, hydergine, idebenone, PQQ, pregnenolone, SAMe

Multiple Sclerosis (also see mitochondrial

Photoaging (see radiation & skin problems) Ph balance (rebalancing)

Active H-minus®, Dr. Gordon’s organic greens®, Quinton®

Physical energy improvement

Active H-minus®, ATP-Boost™, Beyond B12®, CoQ10, idebenone, L-carnosine, maca, PQQ, pregnenolone, SAMe, yohimbine

PMS (pre-menstrual syndrome)

Beyond B12®, krill, HRT Plus®, maca, vinpocetine

Premature ejaculation/ ejaculate (also see erectile dysfunction & sex-libido) Oxytocin

Probiotics

Beyond Fiber®, Digestif®, Dr. Gordon’s organic greens®, Quinton®

Prostate (also see cancer)

Beyond B12™, Bone-Pro™, D3-Pro™, DIM-Pro™, dutasteride, finasteride, HRT Plus®, melatonin, Peptide Bioregulator - Libidon®, Prostate-Pro™

Prolactin alteration

Bromocriptine, cabergoline, Gamalate-B6® ®, Gamibetal®

support)

PSA (prostate specific antigen- see prostate)

Nail condition

Radiation (see skin problems)

Melatonin, naltrexone, TRH Gerovital-H3®, krill

RNA support (see DNA support)

Narcolepsy (sleeping in the daytime) Adrafinil, melatonin, modafinil, picamilone

Nitric Oxide release

Nitric-Pro™, Neo40®, Nitric Oxide saliva test strips

Senile dementia (also see cognitive & memory) Alzheimer’s: Centrophenoxine, CurcuminSR™, galantamine, hydergine, memantine General support: Anacervix®, aniracetam, piracetam, pramiracetam, vinpocetine, Wobenzym®

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

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Parkinson’s: Azilect®, bromocriptine, cabergoline, deprenyl

Senility

Gerovital-H3®, NeyGeront®

Sex (libido, also see erectile dysfunction & premature ejaculation)

Andro-Pro™, deprenyl, maca, oxytocin, Vigor-Pro™, yohimbine

Skin problems

Acne: Nexiclear® Anti-glycation: Aminoguanidine, L-carnosine Anti-oxidant: Crème-Pro™ Protector Cancer (non-melanoma): BEC5® Curaderm Cellulite: Crème-Pro™ Celluless Collagen: Hy-Col™ Environmental: Crème-Pro™ Protector Fine lines: Crème-Pro™ Smoother General support: Gerovital-H3®, Quinton®, thyroid Hyaluronic acid: Hy-Col™ Infections: Silver protein, Thym-Uvocal® Moisturizer: Crème-Pro™ Moisturizer Psoriasis: Nexiclear® Radiation: Crème-Pro™ Protector, melatonin Scars/ stretch marks: Tamanu oil Sun spots: BEC5® Curaderm Wounds: HemaGel® Wrinkles: Retin-A®

Sleep disorders (both a lack of & too much)

5HTP, adrafinil, ATP-Boost™, L-tryptophan, melatonin, modafinil

Smoking cessation 5HTP

Sports (see growth hormone, estrogen alteration, physical energy & testosterone)

Stress (also see cortisol)

5HTP, Gamalate-B6®, Gamibetal®, Gerovital-H3®, maca, L-tryptophan, melatonin, NeyGeront®, oxytocin, picamilone, phenytoin, propranolol, pregnenolone

Teeth & gum disorders

Doxycycline, Gengigel®, NeyDent®, silver protein, Quinton®, zeolite

Telomeres (also see DNA support) Krill, L-carnosine, TA65®

Testosterone & testes (also see fertility and prostate)

Andro-Pro™, Arimidex®, Beyond B12®, Beyond GHS®, DIM-Pro™, melatonin, oxytocin, Peptide Bioregulator Testoluten®, TRH, Vigor-Pro™

Travel (see frequent fliers) Triglycerides (see blood disorders) Veterinarian (see animal use) Vigor

Vigor-Pro™

Vitamins (also see minerals)

Benfotiamine, Beyond Chelation Improved®, Bio- En’RGy®, Cardio-Pro™, CoQ10, Gamibetal®, Gamalate®, Nitric Pro™, PQQ, pyridoxamine, Xan-Pro™

Water

Active H-minus®, Quinton®

Weight gain

Andro-Pro™, Beyond GHS®, Gamalate®, Gamibetal®, sermorelin

Weight loss

5HTP, acarbose, aminoguanidine, ATP-Boost™, benfotiamine, Beyond Fiber®, Diet-Pro™, DIM-Pro™, Dr. Gordon’s organic greens®, galantamine, L-tryptophan, metformin, thyroid, TRH, Xan-Pro™

Well-being (also see depression)

Active H-minus®, Aniracetam, ATP-Boost™, Beyond B12®, deprenyl, Gamalate-B6®, Gerovital-H3®, krill, melatonin, picamilone, piracetam, pramiracetam, SAMe, Thym-Uvocal®, thyroid, Wobenzym®

Stroke

Anacervix®, aniracetam, Boluoke®, hydergine, idebenone, nicergoline, Nitric-Pro™, picamilone, piracetam, PQQ, pramiracetam, pregnenolone, vinpocetine

Stomach (see digestive) Sunburn (see radiation) Syndrome X (metabolic syndrome)

Aminoguanidine, ATP-Boost™, krill, melatonin, metformin

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www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com


Introducing Check Process – A New Online Check Payment Option Check Process is a brand new e-Checking service that we’ve been trialling for a few months on the site. It works just like a normal check, if on your next order you want to use this method simply follow the steps below: 1. On check out select the Check process payment option. 2. Enter your normal delivery and billing information plus the following when prompted: a. Your bank account number b. Your bank routing number (the 9 digit US Bank routing number) c. Your phone number

How to order from IAS Internet USA & world www.antiaging-systems.com UK/ EU www.antiageing-nutrition.com Japan www.japanias.com

Email USA & world ias@antiaging-systems.com Japan iasjapan@antiaging-systems.com

Phone USA 1-866 800 4677 (orders only) 1-415 992 5563 (enquiries) Japan 050 55 329606 EU & world +44 208 123 2106 UK 0208 123 2106 Skype antiaging-systems.com

d. And then e-Sign your check. 3. Your order will then be processed within 2 to 10 working days depending on your bank. 4. Once the payment leaves your account notify us with some proof and we will dispatch the products you have ordered E-checking works by directly charging you via your checking account at your bank just like a regular check. Alternatively you can call us with your order and information and we can charge your account for you. This new option is currently only available to US customers and means that we will no longer be accepting personal checks or money orders. We are always interested in what you think so please send us your feedback via ias@antiaging-systems.com

Fax USA Japan EU & world UK

1-415 366 1503 0367 40 7800 +44 208 181 6106 0208 181 6106

Mail IAS Ltd, PO Box 19, Sark GY9 0SB, Great Britain www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

51


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Aging Matters Issue 3 2013