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Antidiabetic" refers to substances or medications that are used to manage and treat diabetes mellitus, a chronic condition characterized by elevated blood sugar levels. These antidiabetic agents work through various mechanisms to regulate blood glucose levels and improve insulin sensitivity. Here's a comprehensive overview of antidiabetic medications and their role in diabetes management:
Types of Antidiabetic Medications:
Insulin: Function: Insulin is a hormone produced by the pancreas, and it plays a crucial role in regulating blood sugar. In people with diabetes, either the body doesn't produce enough insulin (Type 1 diabetes) or the cells don't respond properly to insulin (Type 2 diabetes). Insulin injections or pumps are used to replace or supplement natural insulin. Types: Rapid-acting, short-acting, intermediate-acting, and long-acting insulin. Oral Antidiabetic Drugs: Biguanides (e.g., Metformin): Function: Reduces glucose production in the liver and improves insulin sensitivity. Sulfonylureas (e.g., Glipizide, Glyburide): Function: Stimulates the pancreas to release more insulin. Dipeptidyl Peptidase-4 (DPP-4) Inhibitors (e.g., Sitagliptin, Saxagliptin): Function: Increases insulin release and reduces glucagon production. Thiazolidinediones (e.g., Pioglitazone, Rosiglitazone): Function: Improves insulin sensitivity in the muscles and fat cells. SGLT-2 Inhibitors (e.g., Canagliflozin, Empagliflozin): Function: Blocks reabsorption of glucose in the kidneys, leading to increased glucose excretion in urine. Alpha-glucosidase Inhibitors (e.g., Acarbose, Miglitol): Function: Slows down the digestion and absorption of carbohydrates, reducing post-meal blood sugar spikes. Injectable Antidiabetic Drugs:
Glucagon-like Peptide-1 (GLP-1) Receptor Agonists (e.g., Exenatide, Liraglutide): Function: Stimulates insulin release, slows gastric emptying, and reduces appetite. Amylin Analogs (e.g., Pramlintide): Function: Slows down gastric emptying and reduces post-meal blood sugar levels.
HOW EUGENIA JAMBOLANA (JAMUN) EXTRACTS OVERCOME ANTIDIABETIC