Opioids are medications that work on opioid receptors in order to generate morphine-like effects. These are mainly used therapeutically to relieve pain and are often abused by individuals addicted to them. Opioids comprises opiates, a conventional name that points to drugs that are derivatives of opium, including morphine. Constipation means bowel actions that are sporadic or hard to go by. The fecal matter is often dry and hard. Some of the other symptoms include bloating, abdominal pain, and feeling the same as if the person has not passed bowels completely. Difficulties from constipation include anal fissure, fecal impaction, or hemorrhoids. Opioid-induced constipation is one of the most prevalent adverse effects connected with long-time use of opioids, which have a detrimental impact on the quality of life of the individual.