Meet SKINVIVE™: The only hyaluronic acid injectable treatment that can deliver up to 9 months of deep† hydration‡ with just one treatment2,3,§,||
|| A touch up treatment may be required at the clinician’s discretion.1
SKINVIVE™ is a hyaluronic acid injectable treatment which deeply† hydrates‡ the skin to enhance texture,¶ tone (colour),** and radiance†† of the face, neck, hands, and décolletage.1,3-5
Please find the important safety information on page 8. This content is intended for UK and Irish (>18yrs) adult audiences only. Produced and funded by Allergan Aesthetics, an AbbVie company.
Adverse events should be reported. Reporting of side effects:
UK patients: If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can help by reporting side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/ or via the MHRA Yellow Card app, available in the Google Play or Apple App Stores. Adverse events should also be reported to AbbVie at ProductSurveillance_EAME@allergan.com. By reporting side effects, you can help provide more information on the safety of this product. Irish patients: If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via www.hpra.ie.
Uncover the secret to long-lasting ‡‡ hydration3,‡ and healthy-looking skin.1,*
SKINVIVETM keeps on working for up to 9 months so you can enjoy a lasting glow.1,††
Unlock the benefits of long-lasting,‡‡ deep† hydration,3,‡ for radiant†† skin that’s smooth to the touch.1,¶
One treatment.3, Up to 9 months of deeply † hydrated‡ skin.3
Over 90% of SKINVIVE™ patients were satisfied with their results1,§§
For our skin to look its best, hydration is essential.6-8 Its surface, texture, elasticity, tone and glow (ability to reflect light) are all largely determined by its hydration.7,9-11
SKINVIVE™ is a hyaluronic acid treatment that can be injected into the dermis of the face, neck, décolletage, and hands.4,5 It can offer long-lasting‡‡ hydration,‡ improves skin smoothness,¶ and visibly reduces the appearance of fine lines.1,3,5,‡
Unlike topical creams that only work on the surface,12 SKINVIVETM goes deeper,† targeting the deep layers of your skin to deliver hydration3,‡ from the inside out.6 So, how does it work?
SKINVIVE™ attracts and retains water, using hyaluronic acid to increase your skin’s hydration.13-15
SKINVIVE™ increases hydration‡ where it’s needed, improving skin smoothness,¶ skin tone (colour)** and the appearance of fine lines‡ after just one treatment.1,3,5,||
SKINVIVE™ increases expression of a naturally occurring hydration marker deep in your skin over time,6,16,|||| to offer long-lasting‡‡ hydration‡ for up to 9 months.3
Looking for hydration that lasts? Ask your practitioner about SKINVIVE™ today.
Your SKINVIVE™ treatment
Ready for smoother-looking skin?,1,¶ Here are some things you’ll need to know about what happens before and during your SKINVIVE™ treatment.
Before treatment
We take your beauty seriously. During your consultation, your practitioner will work with you to craft a treatment plan that meets your individual beauty goals.3,17,18 As well as the areas you’d like to focus on, they’ll consider the levels of hydration across your face, neck, décolletage and hands.4,5
On the day
To make your experience as comfortable as possible, SKINVIVE™ contains Lidocaine, a mild local anaesthetic.5
After your treatment, your practitioner will provide an Aftercare Leaflet with helpful tips on what to expect and how to care for your skin.
SKINVIVE™: for patient satisfaction 1,§§
It’s quite amazing how something that’s been an area of insecurity for me … could be fixed just with this one treatment.
I feel like my skin looks plumper and I actually can’t stop touching it, …it feels so smooth.
Kate, Before
Kate, After
Anna, Before
Anna, After
Anna,¥
Kate,¥
It’s time to restore your skin’s naturallooking glow.††
Ask your practitioner about SKINVIVE™ today.
Models treated with SKINVIVE™ by JUVÉDERM®. Actual treatment results may vary. Images are for illustrative purposes only. You should always consult a healthcare professional to help you decide if SKINVIVE™ is right for you, taking into account your individual assessment and medical history. They will also provide you with a full list of side effects. Like all medical procedures, treatments with SKINVIVE™ may cause side effects.5 To minimise the risks of potential side effects, SKINVIVE™ should only be administered by medical practitioners who have appropriate training and experience in injection techniques and are knowledgeable about the anatomy in and around the site of injection.
* Lasting up to 9 months as reported by 76.2% of patients (from a subset of 127 patients at 9 months; 1 subject did not respond; n=131 initially enrolled) in a composite satisfaction score, which includes how healthy their facial skin looked.1
† Skin hydration was measured using the MoistureMeterD instrument with the XS 5 and S 15 probes (depth of effective measurement: 0.5 and 1.5 mm, respectively).3
‡ Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and top-up treatment administered at Day 30 (n=31) to correct asymmetry.3
§ Based on a search of published clinical studies of injectable HA treatments in March 2023. A duration of 9 months of skin hydration was established with SKINVIVE™.2
|| A touch up treatment may be required at the clinician’s discretion.1-3,5
¶ Lasting up to 9 months, as reported by 55.1% of patients (from a subset of 127 patients at 9 months; n=131 initially enrolled) in a composite satisfaction score, including how smooth their facial skin looked.1
** Lasting up to 9 months, as reported by 67.7% of patients (from a subset of 127 patients at 9 months; 3 subjects did not respond; n=131 initially
Potential side effects associated with SKINVIVE™ by JUVÉDERM® include temporary injection-site reactions such as redness, swelling, itching, pain, firmness, bumps, bruising, and discolouration. These reactions may occur immediately or may be delayed. As with any injection, there is a risk of infection. This is not a complete list of side effects. If inflammatory reactions persist for more than one week, or if any other side effects develop, seek medical attention as soon as possible.5 Please refer to SKINVIVE™ by JUVÉDERM® Directions for use (DFU) for a full list of indications, contraindications, precautions for use, and adverse events.
For further important safety information and other useful information ahead of your SKINVIVE™ consultation please visit www.skinvive.co.uk.
enrolled) in a composite satisfaction score, including satisfaction with their skin’s tone (colour).1
†† Lasting up to 9 months as reported by 63% of patients (from a subset of 127 patients at 9 months; n=131 initially enrolled) in a composite satisfaction score, including how radiant their facial skin looked.1
‡‡ Long lasting is up to 9 months following a single treatment.3
§§ Subjects completed the FACE-Q Satisfaction With Skin scale at baseline (Day 0, before treatment), Months 1, 4, 6, and 9 (before repeat treatment, if received), and Month 1 after the repeat treatment (n=131; n=62 received repeat treatment). The Satisfaction With Skin scale is a validated patient-reported outcome instrument designed to assess the impact of treatment from the subject’s perspective. The scale comprises 12 questions about satisfaction with different facial skin attributes (e.g. smoothness, clearness, radiance). Responses are rated on a 4-point scale (1: very dissatisfied, 4: very satisfied). Scores for each item were summed and converted to a scale score (range: 0–100; higher scores indicate greater satisfaction) using the algorithm developed by the FACE-Q developers.1
|| || Data derived from a prospective, non-randomised, interventional, open-label study where 11 healthy patients (men [n=2] and women [n=9]) received intradermal VYC-12L treatment on the volar forearm. Clinical probes assessed skin quality at baseline and Months 1 and 3 post-treatment. Punch biopsies were collected at Months 1 and 3 posttreatment to evaluate histologic and genomic changes.6
References: 1. Ogilvie P et al. J Cosmet Dermatol. 2020;19(5):1065–1070. 2. Allergan Aesthetics. Data on file. SKINVIVE™ by JUVÉDERM® – 9-month duration of skin hydration in clinical trials. REF-108945. March 2023. 3. Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798. 4. Allergan Aesthetics. Data on File. Juvéderm® VOLITE Treatment Area. REF-80815. March 2019. 5. SKINVIVE™ by JUVÉDERM® DFU. 20081699. Revision 2023-10-04. 6. Safa M et al. Clin Cosmet Investig Dermatol. 2022;15:411–426. 7. Humphrey S et al. Dermatol Surg. 2021;47(7):974–981. 8. Michalak M et al. Nutrients. 2021;13(1):203. 9. Fisher G et al. Arch Dermatol. 2008;144(5):666-672. 10. Walker M. Int J Pharm. 2022;622:121850. 11. Dabrowska AK et al. Skin Res Technol. 2018;24(2):165-174. 12. Goldie K et al. Clin Cosmet Investig Dermatol. 2021;14(14):643-654. 13. Allemann IB and Baumann L. Clin Interv Aging. 2008;3(4):629–34. 14. De Boulle K et al. Dermatol Surg. 2013;39(12):1758-1766. 15. Salwowska NM et al. J Cosmet Dermatol. 2016;15(4):520-526. 16. Alexiades M et al. Dermatol Surg. 2023;49(7):682–8. 17. Zarbafian M et al. Dermatol Surg. 2022;48(3):369–72.
