GHS Proceedings Fall 2018 vol. 3.1

December 2018 | Volume 3 | Issue 1 | ISSN 2475-837X (print) | ISSN 2475-8434 (online)

Clemson University Nursing building, Greenville, SC

Greenville Health System and Palmetto Health are becoming

Why Prisma Health?

Since we launched our new health organization last November, we have made great progress by building on the strength and legacies of Greenville Health System and Palmetto Health. Together, we are looking at health in a completely new way.

In early 2019, we will unite under one name, one logo and one way of delivering health care.

Because the name Prisma Health is unique, we can make it our own. Our bold, fresh visual identity includes sharp angles and bright, vibrant colors that distinguish us from traditional health care providers in our region. The design of the letters is intentional and engaging, evoking the facets of a prism. The name and logo reflect the multifaceted, dynamic organization we are today, and light the way for all we are becoming.

What stays the same?

We will continue to honor the sacred relationships our patients and their families have with their physicians and advanced practice providers. Your doctor won’t change. Your hospital won’t change. Your physician practice will stay the same, too. Only our company names and logos will change to reflect our new unified organization.

We continue to be dedicated to transforming health care through education and clinical research. Collaborating with our academic partners, we are teaching the next generation of physicians, nurses, dentists and other medical professionals, and investing in research to improve the lives of those we serve.

And we continue our commitment to keep health care local. By coming together as one, we’re shaping our own future so we may continue to improve the health of all South Carolinians.

What’s our promise?

Inspire health. Serve with compassion. Be the difference.

Our 30,000 team members are dedicated to supporting the health and well-being of you and your family. To learn more about how we will serve you, visit PrismaHealth.org.

PrismaHealth.org

December 2018 Volume 3 | Issue 1

The peer-reviewed journal of Greenville Health System

Vision: To transform health care through the publication of relevant, innovative, and multidisciplinary scholarship concerning advancements in clinical, academic, and translational research

Editor-in-Chief: William D. Bolton, MD (wbolton@ghs.org) Managing Editor: Jerry Salley, BA (gsalley@ghs.org) Associate Editors: A. Michael Devane, MD; David P. Schammel, MD; Jeffrey W. Elder, MD; Timothy P. McHenry, MD; Naveen N. Parti, MD; Jeremy A. Warren, MD

Editorial Board: Irfan M. Asif, MD; Jagannadha R. Avasarla, MD, PhD; Molly Benedum, MD; Susan

Bethel, MSN, RN, NE-BC; Parampal Bhullar, MD; Matthew D. Bitner, MD, MEd, FACEP; Eric S. Bour, MD, MBA, FACS, FASMBS; John S. Bruch, MD, FACE; Nichole Bryant, MD; Christopher Campen, PharmD, BCOP; Joni Canter, MBA, ATC; Christopher G. Carsten III, MD; Anna L. Cass, PhD, MPH; India Chandler, MD; Catherine M. Chang, MD; F. Tich Changamire, MD, ScD, MBA; Patricia L. Cheek, MD; John D. Cull, MD; Patrick J. Culumovic, MD; James R. Davis, MD; Lauren D. Demosthenes, MD; Kacey Y. Eichelberger, MD; M. Carmela Epright, PhD; J. Alex Ewing, MS; Sarah R. Farris, MD; Lawrence D. Fredendall, PhD; Sagar S. Gandhi, MD; Bruce H. Gray, DO; Steven B. Holsten Jr, MD, FACS; William W. Hope, MD, FACS; Matthew F. Hudson, PhD; J. Terrill Huggins, MD; Sandip Jain, MD; Lindsay H. Jones, CRNA; J. William Kelly, MD; Laura H. Leduc, MD; Bruce A. Lessey, MD, PhD; Ervin L. Lowther, MD; Charles G. Marguet, MD; Nancy Markle, RN ; Brian P. McKinley, MD, FACS; Paul B. Miller, MD; Ryan Miller, Sr Embryologist; Benjie B. Mills, MD; S. John Millon, MD; Ivaylo I. Mitsiev, MD; Bryan S. Moon, MD; John S. Morris, MD; Phillip Moschella, MD, PhD ; Bryce A. Nelson, MD, PhD; M. Jason Palmer, MD; Puraj Patel, DO; Nirav T. Patil, MBBS, MPH; Sarah B. Payne-Poff, MD; Larry E. Puls, MD; Krista Ramirez, PharmD, BCPS; Vinayak S. Rohan, MD; Robert A. Saul, MD; Kerry K. Sease, MD, MPH; Rhett M. Shirley, MD; Dane E. Smith, MD; John A. Spratt, MD; Antine E. Stenbit, MD, PhD; Michael Stewart, MD; Jeremy Stuart, PhD, MPH; Laurie M. Theriot Roley, MD; Steven D. Trocha, MD; Adam B. Tyson, MD; John Van Deman III, MD; Diana Vargas Vives, MD; David J. Walsh, MD; Thomas L. Wheeler, MD; Michael W. Wiederman, PhD; Christopher C. Wright, MD; Steven L. Young, MD; Yuliya Yurko, MD

Editorial Services: Jeanine Halva-Neubauer, MA; Jerry Salley, BA Produced By: GHS Creative Services Greenville Health System Proceedings (GHS Proceedings) is a peer-reviewed medical journal that represents the top academic and clinical research activities happening at GHS and throughout the world. GHS Proceedings is published twice a year (spring and fall) and is a primarily online journal consisting of original research, review articles, case reports, editorials, book reviews, and more. GHS Proceedings’ mission is to provide high-quality publications on health care innovation and delivery (university.GHS.org/Proceedings).

All statements and opinions expressed in GHS Proceedings are those of the authors and not necessarily those of Greenville Health System, its board of trustees, or any of its affiliates.

To receive upcoming issues by email, contact GHS Proceedings at Proceedings@ghs.org.

Copyright © 2018 Greenville Health System. All rights reserved.

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Table of Contents Special Articles 5

A Selection of Abstracts Presented at the 2018 GHS Health Sciences Center Research Showcase

23 Full List of Abstracts Presented at the 2018 GHS Health Sciences Center Research Showcase

Miscellany 29 2018 Greenville Health System Residents and Fellows 30 2018 Graduates of Greenville Health System and University of South Carolina School of Medicine Greenville 31 Publications and Abstracts of Greenville Health System Medical and Scientific Staff, July 2017June 2018

About the 2018 Research Showcase The 2nd Annual Research Showcase, presented by GHS Health Sciences Division of Research and Scholarship, took place April 13 at GHS Greenville Memorial Hospital. This event promotes translational research activities and collaborative work with the system and its three primary academic partners: Clemson University, Furman University, and the University of South Carolina. More than 75 posters were accepted for display. Awards were presented in several categories, which can be found on Page 23.

On the Cover Clemson University Nursing building opened August 2018 on Greenville Memorial Medical Campus. In the foreground is the building’s connector to University of South Carolina School of Medicine Greenville.

Photo by Kris Decker/Firewater Photography

Guidelines for authors are available at university.ghs.org/proceedings/authors. Completed manuscripts may be submitted online (university.ghs.org/proceedings/submit) or emailed to Proceedings@ghs.org.

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Special Article

A Selection of Abstracts Presented at the 2018 GHS Health Sciences Center Research Showcase Factors Affecting Salvage Rate of Infected Prosthetic Mesh Hamza Abbad, Benjamin Hancock, William Cobb, Alfredo Carbonell, and Jeremy Warren Prosthetic mesh infection (PMI) is a challenging complication after ventral hernia repair (VHR).

No clear optimal treatment strategy exists, leaving only experience and judgment to guide surgical decision making.

Retrospective review of patients with PMI was performed. Subsequent abdominal operation (SAO) constitutes any intra-abdominal operation occurring after the index hernia repair prior to PMI presentation. Any mesh removal was considered salvage failure. Analysis was performed using Chisquare test, Fisher’s exact test, or Mann-Whitney U test.

We identified 165 instances of PMI. Most cases (60%) involved intraperitoneal mesh. Thirty-eight percent of patients had an SAO, 64.1% of which were CDC wound class 2, 3, or 4; 67.2% involved intraperitoneal mesh. Enteroprosthetic fistula was found in 15.2% of cases. Mean time to presentation was 17 months after index hernia repair or SAO for infection alone and 54 months when a fistula was present (P = .015).

Macroporous polypropylene mesh was salvaged in 66.7% of cases overall and 72.7% when positioned in an extraperitoneal space. Mesh salvage was not possible in any case involving composite or PTFE mesh and rarely for microporous polypropylene (7.7%), multifilament polyester (5.9%), or intraperitoneal mesh (6.1%). Closure of the defect after mesh removal, with or without component separation or mesh reinforcement, significantly lowers recurrence rate (P < .001).

PMI involving composite, PTFE, multifilament polyester, or microporous polypropylene mesh requires explantation. Infected macroporous polypropylene mesh in an extraperitoneal position is salvageable in most cases. Risk of secondary mesh infection after SAO, particularly with intraperitoneal mesh, should be considered during index VHR.

Volumetric Analysis of Patients Undergoing Abdominal Wall Reconstruction After Preoperative Progressive Pneumoperitoneum John Allen, Jeremy Warren, and Joseph Bittle Introduction: Preoperative progressive pneumoperitoneum (PPP) is a method of increasing abdominal cavity volume prior to repair of massive incisional hernias with loss of abdominal domain (LOD).

We hypothesize that the increase in abdominal cavity volume after PPP is adequate to accommodate the initial hernia contents.

Methods: Retrospective review of all PPP patients over a 10-year period was performed. Volumetric analysis was conducted before and after PPP as described previously. The accommodating volume (AV) was defined as the abdominal cavity volume (ACV) – (pre-PPP ACV + pre-PPP hernia sac volume). Primary outcomes were AV, change in length, and abdominal wall musculature. Secondary outcomes were length of stay, surgical site occurrence, surgical site infection, recurrence, and readmission.

Results: Twenty-nine patients underwent PPP. Mean hernia width was 18.6 cm, with an ACV:HSV ratio of 40%. Mean time of PPP was 7.7 days. Mean increase of ACV after PPP was 3.3 L with GHS Proc. December 2018; 3 (1): 5-22

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mean AV of 0.37 L. All repairs were open with the majority having mesh in retromuscular position (75.9%). Average increase in oblique muscle complex length and rectus muscle width was 2.57 cm and 1.04 cm, respectively.

Fascial closure was achieved in 65.5% of cases. The AV significantly impacted fascial closure, with a mean AV of 1.1 L when fascial closure was achieved and -1.6 L when closure was not achieved. Similarly, increasing hernia width impacted closure, with a mean width of 24.2 cm in those unable to be closed and 15.6 cm when closure was possible. Complications included SSO in 48% of patients, SSI in 27.6%, and SSO requiring intervention in 71.4%. Recurrence was 24.1% with mean 26.7-month follow-up.

Conclusion: Patients with loss of domain benefit from PPP by increasing ACV and lengthening abdominal wall musculature to accommodate initial herniated contents. Greater hernia width, ACV:HSV, and AV predict ability to close fascia.

Assessing Barriers to Implementing Shared Decision Making Alexa Bianchi, Brittany Crum, and Meenu Jindal Shared decision making (SDM) is a highly valued method of patient-centered care, but extensive studies show a surprisingly lower rate of implementation than expected with such an effective model. We are curious about what is preventing physicians from interacting with their patients using a SDM approach specifically at our internal medicine clinic at Greenville Memorial Hospital (GMH).

Internal medicine residents at GMH were invited to fill out a presurvey that subtly assessed their knowledge of SDM. Residents then listened to a lecture on SDM and took a posttest to reassess their actual implementation of SDM and perceived barriers to implementing this type of patient-physician interaction.

Residents were found to highly value SDM but did not implement it as much as expected. They reported time, patient education, and lack of efficient decision-making aids as the biggest barriers to implementing SDM. With these barriers defined, our next step is to create a shared decision-making aid for one of the more difficult and time-consuming physician-patient discussions we see in our clinic: colonoscopies. The interactive in-office decision aid will easily outline the disease, risks, benefits, procedure, and other pertinent aspects of colonoscopies so that the patient can read and formulate questions before seeing the physician. Our intention is to save time and increase patientsâ&#x20AC;&#x2122; understanding and investment in their health.

The global impact on health will benefit patients in low health literacy populations who can begin to understand more about their health, leading to increased patient adherence, enhanced patient-physician rapport, and decreased medical costs.

Early Warning Response System in GHS School-Based Health Centers: Connecting Students to Mental Health Care and Social Supports Holly Bryan, Laura Rolke, Sarah Griffin, Jacqueline Forrester, Laura Johnson, and Kerry Sease Greenville Health System (GHS) has partnered with the United Way to establish 4 School-Based Health Centers (SBHCs) in high-poverty neighborhoods. SBHCs provide a unique opportunity to reach adolescents in an accessible setting.

High-risk students are identified through the Early Warning Response System (EWRS). EWRS is a real-time data dashboard that monitors attendance, behavior, and grades. Each EWRS student is recommended to be referred for a SBHC appointment. A comprehensive assessment (eg, HEADSS, PHQ2) is completed to determine well-being and screen for risks associated with social determinants of health. While the SBHCs do treat acute illness and manage chronic conditions, the service 6

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS targets students at highest risk for dropping out to better understand what is happening in their lives socially and emotionally.

The purpose of this study was to identify how many SBHC visits were completed by EWRS students, the number of screenings, and the result of these screenings. Chart abstraction and analysis revealed 784 SBHC visits during the 2016-2017 school year, 20% of which were EWRS referrals. A total of 94% were provided a screening, and 88% revealed complicated physical, emotional, behavioral, or social health concerns. Students were connected to services (eg, insurance) and outside care (eg, medical homes and specialists). Of all students seen by the SBHC, 94% were able to return to class.

SBHCs are able to help those students most at risk of dropping out and intervene to more effectively address the underlying issues contributing to presenting physical ailments, poor school performance, and behavior.

Beyond Bates: Advanced Physical Exam Series for Medical Students Ryan Dean and Steven Connelly Purpose: To develop a curriculum for medical students that teaches proper technique and choice of both routine and advanced physical exam maneuvers as they relate to medical decision making in clinical practice.

Methods: A 2-week pilot course was created in partnership with the University of South Carolina School of Medicine Greenville. JAMA Rational Clinical Examination and the Evidence-Based Physical Diagnoses were used to develop the curriculum focusing on various topics relevant to internal medicine. Both faculty and residents assisted in leading the course.

Results: Five fourth-year medical students enrolled in the pilot course. A 21-question precourse assessment and a 20-question postcourse assessment were administered.

Precourse average: 12.4/21 points (59.1 ± 12.9%). Postcourse average: 16.8/20 points (84.0 ± 11.4%).

All students demonstrated an improvement in their percent score by 25 ± 10.6%. An oral final assessment was developed with 4 clinical scenarios using the Greenville HealthCare Simulation Center. Grading was based on five clinical categories.

Average oral score: 34.8 out of 40 points (87 ± 8.9%).

Students provided feedback explaining that the afternoon physical exam rounds were most helpful for learning. Students requested more structured teaching on maneuver technique.

Conclusion: After participating in the pilot course, students demonstrated improved knowledge and implementation of the physical exam for clinical decision making and cost-effective care. Results from the pilot will be used to improve a follow-up course that has already been expanded to include 8 students.

Antibiotic Irrigation of the Surgical Site Decreases Incidence of Surgical Site Infection After Open Ventral Hernia Repair Lily Fatula, Allison Foster, Hamza Abbad, Joseph Ewing, Ben Hancock, William Cobb, Alfredo Carbonell, and Jeremy Warren Purpose: Antibiotic lavage of the surgical field before abdominal wall closure has been shown to lower the incidence of both intra-abdominal and soft-tissue SSI. We hypothesize this combination decreases incidence of surgical site infection (SSI) after open ventral hernia repair (OVHR).

Methods: Retrospective review of OVHR with mesh at a single high-volume center (Greenville Health System Hernia Center) from 2008-2017 was performed. All patients were repaired in an open fashion with mesh, primarily in the retromuscular space. Three groups were identified: (1) patients receiving no antibiotic irrigation (Group 1); (2) gentamicin (G) alone (Group 2); or (3) G + clindamycin (C) irrigation (Group 3). Analysis was completed using Chi-square or Fisher’s exact test GHS Proc. December 2018; 3 (1): 5-22

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(for n <5), ANOVA, or Kruskal-Wallis test, and, finally, logistic regression to determine the effects of irrigation on SSI. Results: We identified 852 patients undergoing OVHR. No irrigation was used in 260 patients, G alone was used in 266 patients, and G + C was used in 299 patients; 27 patients were excluded because of different antibiotic regimens. Incidence of SSI was also significantly lower after G + C irrigation, but not G alone (Group 1, 16.5%; Group 2, 15.4%; Group 3, 5.0%; P < .001).

Multivariate logistic regression demonstrated significantly increased SSI with contaminated wounds (OR 4; 95% CI 2.0-8.2), dirty wounds (OR 6.3; 95% CI 2.9-13.4), and COPD (OR 4.1; 95% CI 2.46.9), as expected. Use of G + C was an independent predictor of decreased SSI (OR 0.29; 95% CI 0.14-0.58).

Conclusion: Irrigation with a combined G + C antibiotic irrigation significantly reduces the incidence of SSI following OVHR with mesh.

Geographic Variation in the Treatment of Proximal Humerus Fracture in the Medicare Population Sarah Floyd, Joel Campbell, Charles Thigpen, Mike Kissenberth, and John Brooks Purpose: Conservative management has become the preferred initial course of treatment for patients with proximal humerus fracture (PHF); however, surgical management rates vary widely across the country. The objective of our study was to evaluate local area treatment variation in managing acute PHF. Methods: This was a retrospective cohort study of Medicare patients diagnosed with PHF in 2011.

Patients receiving reverse shoulder arthroplasty, hemiarthroplasty, or open reduction internal fixation within 60 days of their PHF diagnosis were classified as surgical management patients. Area treatment ratios at the hospital referral region (HRR) level were calculated as the ratio of the number of patients in the HRR who received surgical treatment over the sum across these patients of their predicted probabilities of receiving surgical treatment.

Results and Summary: Among patients with PHF (Nâ&#x20AC;Ż= 77 053), 15.0% received surgery and 85.0% received conservative management. Patients who were older, had more medical comorbidities, were male, nonwhite, or dual-eligible for Medicaid were less likely to receive surgery (P < .0001).

Surgery rates varied from 6.3% to 25.6% across all HRRs, with variation in South Carolina ranging from 11.5% to 21.2%.

Applicability to Health Care: Given the heterogeneity of treatment effects, it is possible that variation in surgery rates may represent appropriate care in local areas. Alternatively, higher surgery rates may reflect an overuse of surgical treatment that does not result in improved outcomes for patients.

Future analysis will assess the association between higher surgical rates and patient outcomes such as mortality and Medicare spending.

Persistent Functional Neurological Symptom Disorder Spontaneously Remits With ECT Treatment Raphaela Fontana, Frank Clark, and Benjamin Griffeth Background: A 49-year-old Caucasian female has had 3 psychiatric hospitalizations over a 2-year time period since a complicated cardiac ablation that resulted in the patient needing defibrillation for nonsustained ventricular tachycardia. Family and patient both endorse alterations in her mood and emergence of a new debilitating tremor after being told about the cardiac arrest requiring lifesaving measures.

Initially, this patient was treated with psychotropic medications during her first hospitalization, which improved her depression, but not her functional tremor. Approximately 1 year later, she had 8

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS 2 recurrent hospitalizations for acute decompensation with catatonia and significant tremor within a 2-month span. At that time, the patient’s medical workup and imaging were largely within normal limits or found to be unremarkable.

The patient’s catatonic presentation and functional motor tremor resolved with concurrent psychotropic medications (Remeron 30 mg QD, Propanolol 10 mg TID, Zoloft 200 mg QD, Risperdal 1 mg QHS, Ativan 0.5 mg TID), and electroconvulsive therapy (ECT) during both hospitalizations.

A paucity of evidence exists demonstrating the remission of conversion disorder with a multimodal therapeutic approach of ECT and psychotropic medications. This case presentation will investigate the potential use of ECT in treating functional tremor/conversion disorder in a patient with underlying refractory depression.

Objectives: Present a case in which a proposed relationship can be shown between a traumatic event and new-onset conversion disorder. Propose and explore a new treatment modality with ECT for a patient with refractory or treatment-resistant depression and concurrent conversion disorder.

Optimization of Automated Guided Vehicle System in Health Care Facility Kade Gilstrap, Amogh Bhosekar, Tugce Isik, Sandra D. Eksioglu, and Robert Allen Background: Automation in material handling systems has been a key to promoting cost-effective material flow within health care facilities. This research analyzes Automated Guided Vehicles (AGV) use in a hospital. AGVs perform tasks such as moving surgical instruments, drugs, linen, food, and trash.

Use of AGVs has improved staff utilization; however, it has also increased traffic and congestion.

Purpose: The goal of this study is to evaluate the impact of AGV use in the hospital.

Methods: Historical data about travel time for all AGV trips at different times of the day and days of the week have been analyzed.

Results: A Pareto analysis indicated that the majority of AGV travel time is spent in 3 trips. A statistical analysis of these trips demonstrates that the distribution of travel time during peak and off-peak hours is statistically different. The same holds true for travel times during different days of the week.

Difference in travel time is the result of congestion.

Conclusion: Based on these results, we believe that reducing the number of AGVs used and implementing a Kanban system, which maintains only a fixed number of AGVs active and moving during peak hours, will reduce congestion. This numerical analysis provides the data necessary for developing a simulation model that will identify the right number of AGVs to use in this system at different hours of the day and different days of the week.

Improving Quality to Facilitate Research Amanda Goode, Katie Daniels, and Matthew Hudson Purpose: Federal regulations require that an Institutional Review Board (IRB) review and approve all human subjects research before research initiation. To optimize review efficiency, Greenville Health System’s Office of Human Research Protection (OHRP) revised its policy on adverse event reporting in June 2017. Investigators may now report in aggregate at continuing review all nonserious adverse events that are not unanticipated problems. OHRP examined whether this change reduced the duration from submission to IRB approval.

Methods: There were 1318 IRB submissions from January 2017-March 2017 (before policy revision), with 582 submissions from October 2017-December 2017 (after policy revision). OHRP compared summary statistics and performed analyses by review type (full board or expedited) and time period.

Results: Mean and median full-board review durations decreased from 41.08 and 30 days, respectively, to 24.43 and 22 days, respectively, subsequent to policy change (U = 6067.5; P < .0001). The mean expedited review duration decreased from 20.75 to 13.37 days, while the median was 12 days for both time periods (U = 234 106.5; P < .0002).

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Discussion: Results suggest that OHRP improved IRB efficiency by changing the adverse event reporting process. This change could afford our patients more immediate access to clinical trials and provide system leadership with quicker access to care improvement data. Finally, this improvement may also relieve administrative burden for investigators, study coordinators, IRB chairs, and IRB coordinators. Collectively, these benefits may facilitate sustained research engagement and enhance IRB resource use.

The Correlation Between Residency Applications and Standardized Behavioral Assessments for Gaining Entry Into a Graduate Medical Education Program Vincent Green and Ardalan Ahmadi Purpose: This study’s purpose is to develop a standardized assessment tool for selecting residents into a graduate medical education (GME) program.

Methods: A standardized assessment tool for selecting residents into a GME program was developed by faculty within the Greenville Health System (GHS) Family Medicine Residency. The assessment tool consisted of two parts: (1) a preinterview instrument (maximum total score = 28) assessing board scores, grades during undergraduate medical education, extracurricular activities, letters of recommendation, interest in family medicine, and scholarly activity; and (2) a rubric of behavioral questions (maximum total score = 16) with standardized anchors for objective assessment within the domains of problem solving, resilience, interpersonal communication and professionalism, and emotional intelligence. The tool was used to assess all applicants who interviewed with the GHS Family Medicine Residency during recruitment for the class beginning July 2018.

Results: Overall, 71 applicants (mean age = 27.1 years; 49.3% male, 50.7% female; 80% Caucasian, 7% African American, 3% Hispanic, 10% other) were selected to interview from October 2017-January 2018. The mean preinterview assessment score = 22.73 (range 17-27), behavioral rubric score = 11.46 (range 8-16), and total composite score = 35.4 (range 27-42).

Correlation between the application preinterview assessment and the behavioral rubric measuring interview performance was 37.3%. Low correlations were also found within each individual domain of the preinterview assessment and the behavioral health questions.

Conclusions: Objective tools for selection into GME programs are lacking. Ideal selection criteria include a combination of the candidate’s application and performance during an interview. Data from this investigation suggest little correlation exists between strength of application and interview performance, which highlights the need for measuring both components during the selection of candidates into GME programs.

JUMPing Into Diabetes Control Lauren Hassan, Sheena Henry, Gail Chastain, and Meenu Jindal Background: A study analyzing the results of the Boston Area Community Health Survey confirmed that socioeconomic status has a stronger association with diabetes prevalence than does race. If systems were in place to address socioeconomic barriers, the inequality in diabetes prevalence and complication rates may improve.

Purpose: The construct of this study (named JUMP as an uplifting, motivating title) is to provide patients who have diabetes with a group setting focusing on self-empowerment.

Methods: Groups included 1 or 2 resident facilitators, a diabetes educator, and 5-10 internal medicine clinic patients. The program included 3 weekly sessions consisting mostly of patient-led discussion.

JUMP has graduated 24 participants. As a comparison group, 24 patients were pooled from the list of clinic patients who expressed interest in the program but did not enroll. Patients’ pretest and posttest JUMP HgbA1c levels were measured.

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS Results: JUMP participants showed a statistically significant decrease in HgbA1c. The average preJUMP HgbA1c was 9.3 ± 2.5; post-JUMP level was 8.0 ± 1.9. The difference yielded a mean drop in HgbA1c of 1.3 (P < .001). The control group yielded pre-JUMP HgbA1c of 9.0 ± 2.2 and post-JUMP level of 9.2 ± 2.3, a variation with no significant change (P = .418).

Discussion: The United Kingdom Prospective Diabetes Study found that the rate of microvascular complications from diabetes fell by 25% when comparing patients with a mean HgbA1c of 7.9% to those at 7.0%. Incidence of diabetes-related deaths, myocardial infarctions, and all-cause mortality was significantly lower for each 1% improvement in HgbA1c. This result is promising given that the mean decline in A1c for JUMP participants was 1.3%.

Identifying the Profile of Youth Who Present to the Emergency Department for Psychiatric Reasons Sharon Holder, Dawn Blackhurst, and Eunice Peterson Objectives: This study examines use of Greenville Memorial Hospital’s (GMH) Emergency Department (ED) for mental health visits by the pediatric population over a 5-year period.

Methods: A retrospective study of all psychiatric visits of children age 5-18 visiting the GMH ED from Jan. 1, 2010-Dec. 31, 2014, was conducted. Psychiatric visits were identified using the primary ICD-9 diagnosis codes of 290.0-319.0. The population was categorized into 3 age groups based on schoolage grades: 5-10, elementary; 11-13, middle school; and 14-18, high school.

Demographic characteristics and ED use were compared among the age groups; P values < .05 were considered statistically significant. Hospital Institutional Review Board approval was obtained before the study.

Results: There were 2,700 visits of the study population. This number made up ~11% of the total psychiatric ED visits in the study timeframe (N = 25 411). Total number of visits increased from 380 in 2010 to 698 in 2014 (84% increase). The greatest increase was in the 11-13 age group (137%).

The majority of visits occurred on weekdays (79%); however, the older age groups had a higher percentage of weekend visits (21% vs. 15%). The elementary and middle school groups were predominantly male (60% vs. 40%), while the high school group was predominantly female (52% vs.

48%).

Conclusion: Statistically significant differences were found in ED use characteristics among the 3 age groups. Females were more likely to visit the ED than males. Among the older age groups, those diagnosed with anxiety were more likely to visit the ED. Understanding the profile of youth who use the ED has clinical implications for developing treatment protocols in the ED, community partnerships, and mental illness preventive practices.

Are We Asking the Right Questions? Screening and Counseling for Environmental Tobacco Smoke Exposure at a Federally Qualified Health Center Elizabeth Holt, Jackson Pearce, McKenna Luzynski, Matthew Delfino, and Lochrane Grant Background: Interventions that combine provider training with “practice transformation” techniques can greatly increase screening and counseling for environmental tobacco smoke (ETS) exposure during pediatric visits. A clinic-based family smoking cessation intervention is planned at a multisite federally qualified health center (FQHC) serving rural/suburban patients in the Upstate of South Carolina. Rates of smoking at the FQHC are >2 times the national average.

Purpose: To inform intervention design, we assessed the following: (1) provider practices around screening and education for ETS exposure at the pediatric encounter, and (2) provider-stated barriers to counseling and referral to cessation resources.

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Methods: Medical record data for all 2017 pediatric visits (N = 7997) were analyzed to determine rates of screening and education around ETS. Provider surveys were administered (n = 11) to identify specific education techniques used and key barriers to counseling and referral.

Results: Preliminary analyses revealed that provider-documented screening and/or education for pediatric ETS exposure occurred in 55% of pediatric encounters. Rates varied by provider/clinic site and visit type. Analyses are underway to assess variation by documented respiratory disease.

Initial results from provider surveys revealed that (1) specific education/counseling techniques used vary widely, (2) smoking cessation resources (such as quitline referrals and nicotine replacement therapy) are underused, and (3) practice-wide changes in electronic medical record prompts could increase counseling and referral to cessation resources.

Conclusion: Implementating clinic-based family smoking intervention could increase the quality of patient counseling and frequency of referral to smoking cessation services, reducing morbidity and mortality among a patient population where smoking rates are high. Data from this pilot study will inform future intervention dissemination across the region.

The Effect of Fad Diets on Patients’ Perceptions of Health and Disease Cassidy Hood, Robert Masocol, Alex Ewing, Vicki Nelson, and Irfan Asif Purpose: This study’s purpose was to identify common nutritional perceptions among adult patients in a high-risk family medicine clinic.

Methods and Study Design: The method used was a cross-sectional survey. A paper survey was distributed to adult patients within a high-risk family medicine residency clinic from September 2017-October 2017.

Results: A total of 220 adult patients were surveyed (69% female; 50% African American, 38% Caucasian) with the majority of patients between 25-65 years old (75%) with a BMI >25 (80%).

A total of 45% of patients identified as being overweight/obese, 55% identified as having diabetes, 42% identified as having hypertension, and 29.5% identified as having hyperlipidemia.

Approximately 63% of participants described a healthy diet to include fruits and vegetables, with only 23.6% of those patients eating 5 or more servings of fruits or vegetables per day; 28.6% of participants could not describe what constituted a healthy diet. Also, 31.3% of patients have used fad diets in the past, with only 15.4% of patients considering fad diets healthy.

A total of 30.4% of patients identify the media as a major influence on their dietary choices (18.2% TV and social media).

Conclusions: Participants identified a healthy diet as plant-based, though few follow this recommendation. Nearly 33% of patients report trying a fad diet.

Significance: This study identifies the significant overall lack of knowledge and understanding of appropriate nutrition, including the common belief in and use of fad diets, and the poor insight of chronic disease and its link to nutrition among adult patients in a high-risk family medicine clinic. It is imperative that sufficient patient counseling and education on healthy diets be conducted on a regular basis.

Leader Mindfulness, Unit Well-Being, and Patient Care Chelsea LeNoble, Michelle Flynn, Marissa Shuffler, Nastassia Savage, Sharon Wilson, and Tod Tappert Health care leaders must provide positive environments for their employees and their patients despite staffing shortages, policy changes, and shifting economic demands. Ensuring leaders possess the right skills is critical for everyone—from nurses, doctors, and staff, to patients and their families.

This study considers the impact of leader attributes of mindfulness and emotion regulation on their staff and patients.

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS To examine the impact of leader mindfulness and emotion regulation on unit and patient outcomes, multisource longitudinal data from 698 health care leaders and 123 000 health care employees were analyzed. Mediated regression analyses indicate that (1) leader mindfulness improves emotion regulation strategies and leader-unit relationship quality, and (2) a high-quality leader-unit relationship improves the unitâ&#x20AC;&#x2122;s ability to recover from work stress and provide high-quality patient care.

These results suggest that mindful leaders are more likely to use appropriate emotion regulation strategies at work, foster quality relationships and well-being norms with their staff, and facilitate top-notch patient care.

The ability of leaders to manage themselves and their employees is crucial for health care. When leaders are ineffective, their employees are more likely to burn out, and their patients are less likely to receive effective care. The result not only costs hospitals millions, but also reduces the overall health of patient populations served. These findings highlight the importance of leadership development programs that improve leadersâ&#x20AC;&#x2122; mindfulness and emotion regulation skills and that foster a healthier organizational culture.

Implementation of the Survey of Well-Being of Young Children (SWYC) Form in a Primary Care Office to Improve Screening of Children 2 Months to 5 Years of Age Eric Lessard and Sara Ryder Emerson Introduction: The American Academy of Pediatrics and Bright Futures recommend monitoring all children for developmental progression and social determinants of health at well-child check evaluations. Because a variety of tools are available to meet screening requirements, patients often receive multiple screening forms per visit, which is laborious for families and clinical staff alike.

Tufts University developed a comprehensive screening tool, the Survey of Well-Being of Young Children (SWYC), which includes developmental, interpersonal/behavioral, and social determinants of health screening for children 2 months through 5 years old. Our aim was to use this tool to improve pediatric screening in our clinic by approximately 20%.

Material and Methods: Baseline data for correct distribution of screening tools were obtained from retrospective chart audits of children 0-5 years old seen at the Greenville Health System (GHS) Center for Family Medicine during a 2-month period. The SWYC form was then introduced via small group educational sessions involving physicians and clinic staff. One month after implementation, chart audits were repeated measuring percentage of forms completed by caregivers.

Results: Before SWYC implementation, patients received age-appropriate screening tool(s) 62% of the time. After SWYC introduction, age-appropriate screening tool completion improved to 94%.

Conclusion: This study demonstrates that implementing the SWYC form at the GHS Center for Family Medicine provided more consistent comprehensive developmental and social screening of children 0-5 years old.

Increasing Compliance With Consistent Sterile Procedure During Central Line Fluid Changes in the Small Baby Unit of the Neonatal ICU to Decrease the Central Line-Associated Bloodstream Infection (CLABSI) Rate Melissa Motes and Michael Stewart The purpose of this project was to increase compliance with consistent sterile procedure during central line fluid changes in the Small Baby Unit of the neonatal ICU to decrease the CLABSI rate and maintain the lower rate.

The framework for this quality improvement was the Iowa Model of Evidence-Based Practice. To increase compliance during central line fluid changes, a PICC nurse (nurse using a peripherally inGHS Proc. December 2018; 3 (1): 5-22

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serted central catheter) was present to assist during the line change. Re-education with a skills check-off on sterile technique and proper process for central line fluid changes was also performed on the unit before the intervention began.

Average compliance for this project was 42%. Overall percent change in the average CLABSI rate was 17%, but the overall percent change for CLABSIs related to maintenance was -50%. This quality improvement showed that the implementation of a PICC nurse to assist during central line changes, in addition to routine education, may not result in an overall decreased CLABSI rate, but may result in reduced CLABSIs that can occur during maintenance of central lines.

This project demonstrated that increasing compliance with proper procedure during central line changes, in addition to continued skills check-offs, can reduce CLABSIs caused by maintenance, resulting in decreased negative outcomes in infants with extremely low birth weight.

Can Commercially Available Voice Prompting Automated Electrical Defibrillators (AEDs) Be Utilized Effectively by Grade School Children?

Sally Peterson, Phillip Moschella, Amy Ramsay, and Dotan Shovrin Purpose: Out-of-hospital cardiac arrest survival rates involving AED use in the United States is poor despite known survival benefits. Lack of knowledge is cited as the main barrier to increased use. We sought to evaluate if grade school children can properly use an AED prompted only by the machine’s voice/self-contained written instructions.

Methods: An Institutional Review Board-approved pilot study was conducted using randomly selected grade school children attending a health fair at Clemson University. Participants were given a commercially available AED, surveyed if they had any experience with the device, and then asked to use the device on a simulation manikin. They received only the voice prompting/printed instructions from/on the device itself. The ability to correctly apply/discharge the device across several steps was charted by an observer on a yes/no basis along with the total time (in seconds) to correctly complete AED application.

Results: A total of 35 of 37 students (95%) elected to participate. Of those, 100% of the students had never used the device previously. Of the 35 students, 31 children (88.5%) were able to correctly turn on the device; 24 of 35 students (68.5%) correctly removed and attached the pads to the manikin chest/AED; and 28 of 35 children (80%) correctly discharged the AED shock. Average time to correctly complete AED placement and shock was 81 seconds.

Conclusions: This pilot study demonstrates that grade school children can correctly use an AED with instructions provided by the device itself. Further education and training in grade schools may prove beneficial and cost efficient to improve overall community use of AEDs involving out-of-hospital cardiac arrest.

Reducing Burnout and Improving Meaningful Work Through Medical Resident Poverty Simulation: A Pilot Study Camiron Pfennig and Chelsea LeNoble Health care professionals are at significant risk for burnout, characterized by emotional exhaustion, depersonalization, and reduced personal accomplishment. As the intensity of health care work continues to escalate, the need for interventions aimed at mitigating burnout and increasing providers’ sense of meaningful work is apparent.

Health care professionals may experience burnout symptoms when patients miss appointments or do not adhere to prescribed treatments, as this diminishes a sense of meaning in their work. Many times, these behaviors are not a result of the patients’ lack of effort, but stem from external factors related to socioeconomic status and health disparities. To obtain better insight into the lives of their patients, medical residents at a large hospital system participated in a poverty simulation—an im14

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS mersive experience in which participants take on the identity of a person in poverty and navigate their daily challenges.

To examine the impact of the simulation, 24 medical residents who completed a poverty simulation and 43 medical residents who did not participate reported their sense of meaningful work and emotional exhaustion both before the poverty simulation and again 1 month later. Results indicate that residents who took part in the poverty simulation reported an increase in meaningful work compared to the control group from Time 1 to Time 2. While emotional exhaustion slightly increased for the poverty simulation group, the average score was significantly lower than for the control group.

These findings provide initial support for the effectiveness of a poverty simulation in reducing burnout and improving meaningful work for medical residents.

Initiation of an Osteoporosis Treatment Program at Our Institution Drew Ratner, Billy Clark, Amy Trammell, Laura Boineau, and Kyle Jeray The purpose of this study is to examine the effectiveness of our osteoporosis program at preventing future fragility fractures in our population of patients with hip fragility fractures, including how many patients were started on an osteoporosis treatment.

Institutional Review Board approval was obtained for this retrospective review. We reviewed all patients treated at our institution for hip fragility fractures from January 2013-July 2013. The primary outcome measure was the number of patients who met with the osteoporosis nurse practitioner (ONP) and started an osteoporosis medication. Initiation of calcium and/or vitamin D and subsequent fragility fracture were also examined. In addition, we examined length of stay in hospital, time from admission to surgical intervention, time from surgery to discharge, ambulatory status on admission and discharge, location of discharge, and mortality.

There were 151 hip fractures deemed to be fragility hip fractures during that period. Average time to surgery was 37 hours (SDâ&#x20AC;Ż= 2.1). Forty-two patients (28%) previously had a fragility fracture.

Forty-seven (31%) followed up with the ONP. Of those, 34 were started on an osteoporosis medication, and all of them were started on calcium and vitamin D. Overall, 13 patients re-presented before 2017 with a subsequent fragility fracture (mean time 398 days to refracture), 5 of which were being treated by the ONP. This finding is an improvement compared to nationwide averages (~20%).

This study shows promise for the initial stages of our osteoporosis program in providing osteoporosis treatment following fragility fractures.

Employing the Patient-Centered Collaborative Care Approach: A Case Study of a Complex Geriatric Patient With Psychopathology of TreatmentResistant Depression and Primary Hyperparathyroidism Joel Saul, Sharon Holder, and Jonathan Lokey Primary hyperparathyroidism is a relatively common endocrine disease with many nonspecific physical symptoms as well as potentially serious psychiatric effects. Incidence of the illness, severity of symptoms, and poorer outcomes are all positively correlated with increasing patient age. The Patient-Centered Collaborative Care Approach is a demonstrable method of coordinating patient care, reducing the burden on patient advocates, and improving patient outcomes. Use of the Patient-Centered Collaborative Care Approach has not previously been well described in treating psychiatric manifestations of primary hyperparathyroidism.

Using the example of an elderly woman admitted with complex psychopathology and a diagnosis of primary hyperparathyroidism, this case illustrates the value of the Patient-Centered Collaborative Care Approach in (1) establishing accurate diagnoses, (2) reducing harm from comorbidities, (3) improving patient outcomes, and (4) potentially reducing hospital costs.

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The case exemplifies the potential benefits of implementing the Patient-Centered Collaborative Care Approach in treating a medically complex patient hospitalized for psychiatric complaints.

A diagnosis of primary hyperparathyroidism was made, and a multidisciplinary team treated this patient using the Patient-Centered Collaborative Care Approach. This team involved psychiatry, internal medicine, and endocrine surgery, as well as family members.

Parathyroid adenoma was confirmed and mass was removed surgically. The patient made a rapid and dramatic improvement, and her depressive symptoms remitted. The critical importance of applying clinical flexibility, questioning available data, and employing a collaborative team approach to the evolution of a diagnosis is addressed.

Caring for Caregivers: Identifying Personality Risk Factors in Burnout Development Nastassia Savage, Zachary Klinefelter, Marissa L. Shuffler, Camiron Pfennig, and Ronald Pirrallo Burnout is a well-recognized issue in health care, where it negatively impacts patient care (eg, Atkinson et al, 2017) and physician suicide risk (Shanafelt et al, 2011). Although the estimates of burnout prevalence vary, a study found 50% of medical residents and fellows were burned out and exhibited symptoms of depression (Dyrbye et al, 2014). One predictor has been that personality (eg, extroversion, agreeableness, conscientiousness, intellect, neuroticism) as certain traits were more prone to burnout (eg, McManus et al, 2004; Ripp et al, 2011; Swider and Zimmerman, 2010; Zellars et al, 2000). This study assesses the role of personality in burnout development longitudinally.

We used the mini-IPIP to evaluate personality in 10 first-year ED residents prior to residency (June 2017) and the MBI-HSS to assess burnout before residency and every 4 weeks starting in September 2017. Using general linear model repeated measures analyses, results indicate that extroversion and intellect significantly predict burnout development for emotional exhaustion and depersonalization, and that agreeableness, conscientiousness, and neuroticism did not.

The above results should be used cautiously, as they are limited by the small sample and reliance on self-report survey data. However, they provide some support for the role of personality in burnout development in residents and should be reassessed in other, larger, more diverse samples (eg, departments). Doing so could help target interventions to offer assistance to those residents more at risk for developing burnout than others. Additionally, at-risk residents could be offered extra support and guidance (eg, mentors, relaxation activities) to limit the development of burnout.

Return to Sport as Outcome Measure for Shoulder Instability: Surprising Findings in Nonoperative Management in a High School Athlete Population Ellen Shanley, Charles A. Thigpen, Lauren Ruffrage, Douglas J. Wyland, Michael J. KIssenberth, and John M. Tokish Objectives: Recurrence rates have traditionally been used as a proxy for “failure” when comparing conservatively vs. operatively managed patients with anterior shoulder instability. Return to sport has been evaluated as an outcome proxy after surgical intervention, but no study has compared conservative vs. operative management using sustained return to sport as the main outcome measure. The purpose of this study was to compare results between conservatively and operatively treated patients as to their ability to return to uninterrupted sport in a subsequent season after an anterior instability event.

Methods: We identified and followed 179 scholastic athletes treated for a confirmed diagnosis of anterior shoulder instability. Ninety-seven were treated initially with conservative management; 32 were managed surgically. Patients were excluded if they did not have remaining eligibility to play (were high school seniors) or were treated with benign neglect (neither conservative nor operative treatment). Ultimate success was defined as “return and completion of the subsequent season without time loss due to any shoulder-related diagnosis.” We substratified by age, 16

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS sport, and type of instability event (subluxation vs. dislocation) using ANOVA and binary logistic regression.

Results: In the conservatively managed group, 85% achieved ultimate success by returning to play a complete subsequent season of scholastic athletics in the same sport without time loss due to a shoulder condition. In the surgical group, 72% achieved this status (P < .05). Age did not differ between the 2 groups. Patients were 5 times less likely to return to sport if they had sustained a dislocation requiring reduction compared to a subluxation confirmed as an anterior instability event (OR: 4.96, 95% CI = 1.2-9.6).

Conclusion: Patients treated conservatively for an anterior shoulder instability event were far more likely to have a “successful” outcome than published results if the definition of outcome is changed from “no recurrence” to “completion of a subsequent season in their same sport.” Patients sustaining a subluxation were nearly uniformly successful in doing so. While surgical success using this definition was quite lower, there was likely a selection bias in the decision-making process due to bone loss, surgeon preference, or other factor. Nevertheless, the data would suggest that if a patient’s goal is to return to the same level of sport and complete the next season, conservative management is highly effective. Further study to determine whether these results hold with longer term follow-up is warranted, but the routine fixation of the first-time dislocator based on better outcomes is called into question depending on one’s definition of success.

Using Epic to Measure Referral Rates by Greenville Health System Pediatricians to Developmental and Behavioral Support Services Megan Schmalz, Julia Moss, Jacqueline Forrester, Sarah Griffin, Christopher Wilson, and Kerry Sease The purpose of this study was to examine the rate at which Greenville Health System (GHS) pediatric primary care providers refer patients with developmental and behavioral concerns to Help Me Grow South Carolina (HMG SC) and to understand the most common concerns among children being referred.

The study examined a cohort of patients from May 2016-April 2017 who may have benefited from HMG services based on age (<4 years) and identification of a possible developmental delay (through commonly used diagnosis codes). Referrals to HMG, as well as to early intervention services, were analyzed. In this population (N = 1654), the most frequent diagnoses were general speech and developmental delays. Average age at diagnosis was 20.3 months, with the majority of patients being male (63.3%). A total of 7.8% of patients were referred to HMG; however, 74.2% of patients referred to HMG were connected to early intervention services.

GHS physicians who use HMG are making age- and diagnosis-appropriate recommendations to HMG, resulting in a clinically significant rate of connection to services; however, a missed opportunity exists currently because of low referral rates. The sample also displayed a gender disparity in diagnosing developmental delays and behavioral concerns, similar to results found in existing literature.

The study highlighted the need for a more streamlined approach to physician referral to HMG and other support services. It also informed a pilot project (GHS Pediatric Support Services), whereby physicians can easily refer to HMG and other community services through 1 simple referral within the medical record.

Impact of an Alert Reduction Strategy on Pharmacist Alert Override Rates Within a Clinical Decision Support System John Schoonover, Becky Sawyer, Lucy Crosby, Alyson Ghizzoni-Burns, and Jun Wu Clinical decision support (CDS) provides information electronically to help the clinician make informed treatment decisions. Benefits of CDS include reduced medication errors, improved quality of care, and enhanced efficiency.

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A major consideration of CDS implementation is the large number of clinical checking alerts generated during order entry and verification. If alerts are frequent but not consistently meaningful and actionable, clinicians become desensitized over time. Desensitization, also known as alert fatigue, can lead to clinician frustration and patient harm as important alerts are overlooked. Opportunities exist within CDS systems to customize alerts by various methods, including filtering visibility by certain disciplines only (eg, pharmacists only), filtering by severity level, changing the severity level, and turning off/on completely.

The study objective is to determine if reducing pharmacist-specific alerts reduces alert fatigue (override rates per 100 orders) and improves pharmacist perceptions of utility.

This prospective, systemwide, pre/postintervention, quality improvement study will be conducted over a 6-month period. The preintervention phase will include pharmacist education and a brief satisfaction survey. Following the education and a committee-based review and approval process, CDS alerts will be modified to target a 10% reduction. Pharmacist satisfaction and override rates will be measured and compared to preintervention values during the postintervention phase.

The primary endpoint is pharmacist override rate per 100 orders. Secondary endpoints include change in total number of alerts, pharmacist override reasons, satisfaction survey results, pharmacist intervention data, and number of reported medication events.

Study outcomes and data collection are currently underway.

Comparing Telephone-Based Diabetes Education to Resident Clinic Standard of Care in Uncontrolled Type 2 Patients With Diabetes Henry Schwartz, Caroline Clary, Gail Chastain, and Meenu Jindal Introduction: The morbidity and mortality of type 2 diabetes, as well as the diseaseâ&#x20AC;&#x2122;s contribution to our national health care cost burden, cannot be overstated. The resident clinic with its primarily underserved population of patients offers a unique opportunity for residents to care for notoriously difficult-to-manage patients who have diabetes.

Methods: Fifty-two patients using our internal medicine residency clinic for primary care were enrolled August 2016. Primary enrollment criteria were a diagnosis of diabetes mellitus type 2 and a most recent hemoglobin A1c >9.0 at time of enrollment. Twenty-six patients were randomized into the intervention arm of the study. These patients received 6 months of diabetes education over the telephone via a certified diabetes educator employed by the clinic. The primary outcome measure was hemoglobin A1c as collected by the PCP as part of standard of care.

Results: Following a rolling schedule of enrollment starting August 2016, the intervention arm of the study was completed August 2017. Hemoglobin A1c data were gathered and analyzed comparing trends between the control and intervention arms.

Conclusion: Developing new and innovative ways to improve blood glucose control in historically difficult-to-control patients with diabetes represents an exciting area of ongoing research in primary care medicine. A cost-effective telephone intervention program used to both educate patients and identify barriers to care would be a perfect example of such an intervention. As any intervention needs to be evidence based, this study represents the first stages of development of such a program.

Comparison of High- vs. Low-Fidelity Simulation Models for AHA CPR Training in Middle School Students Bijal Shah, David Wong, Sally Peterson, Phillip Moschella, Amy Ramsay, and Dotan Shvorin Purpose: To test the ability of middle school students to learn American Heart Association (AHA) â&#x20AC;&#x153;CPR Anytimeâ&#x20AC;&#x153; training using both high- and low-fidelity simulation models.

Background: Current rates of bystander CPR in South Carolina remain dismal despite known survival 18

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS benefits. Programs have been targeted at high schools and adult community events with mixed results. Multiple countries have trialed CPR training in elementary and middle schools, but costs of the simulation models necessary for training are expensive and bulky.

Methods: Commercially available high-fidelity simulation manikin models will be assessed against simple air bellows foot pumps to test their noninferiority during AHA CPR Anytime training of 450 students at a local charter middle school. These results will also be compared to a historical cohort of high school students using similar manikin-only based training. We will test for retention and ability using established methods from the AHA included with the training program.

Outcomes: We anticipate that the simple air bellows will provide a noninferior training model as compared to the expensive and bulky manikins. These widely available air bellows are inexpensive and may entice more districts/schools to implement training that would otherwise have been deemed too costly.

Conclusion: This program is designed to expand the scope and dissemination of CPR Anytime training by providing a lower cost/fidelity option comparable to the AHA CPR training, which we hope will improve bystander CPR rates through education of local youth.

Critical Social Thinking and Mindfulness Skills as Levers for Facilitating Health Care Unit Engagement and Unit Climate for Patient Safety: A Longitudinal Examination of the Impact of Conscious Leadership and Professionalism Marissa Shuffler, Chelsea LeNoble, Michelle Flynn, Dana Verhoeven, Nastassia Savage, Pamela Farago, Tiffany Cooper, Sharon Wilson, and Terrie Long In health care, emotional demands and stress can negatively impact relationships among employees, reducing engagement and increasing turnover (Ahearn, 2006). Leaders can play a key role in addressing these challenges. In particular, leaders who are provided with developmental activities to refine the skill of navigating relationships with and among their employees are more likely to set team climates that foster employee engagement and reinforce patient safety.

Empirical evidence has suggested that focusing on self-awareness, social dynamics, and mindfulness may be particularly beneficial for health care leadership. Accordingly, this research provides a multimethod, multisource, long-term examination of the impact of a leadership and professional skill development program focused on such competencies: the Conscious Leadership & Professionalism program. This program is derived from evidence-based practices and principles of leadership development and training design.

Data from 1189 health care units and their leaders were collected over the course of 4 years to evaluate longitudinal effects on unit outcomes of engagement and climate for patient safety. Multilevel structural equation modeling analyses were then conducted.

Program participation and learning are significantly and positively predictive of leader-employee relationships, greater workplace engagement, and positive perceptions of patient safety climate. This type of training program is a promising avenue for continued exploration and application in health care, as it may help to improve both employee engagement and the patient experience.

Strategic Development of a Research Experience Enrichment Program (REEP) in the Emergency Medicine Department Dotan Shvorin, Ronald Pirrallo, Kevin Taaffe, and Phillip Moschella Objective: To establish a Greenville Health System (GHS)-Clemson University (CU) collaboration that seeks to improve patient care processes and outcomes by applying engineering methods within the GHS Department of Emergency Medicine.

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Background: The Creative Inquiry (CI) program matches motivated undergraduate and graduate students with CU faculty to facilitate imaginative engaged learning and cross-disciplinary interactions to produce the next generation of scholars.

Hypothesis: Can the CU CI program be adapted to the GHS health care environment to advance GHS scholarship and workforce development?

Methods: Under the leadership of an embedded CU scholar, 6 teams of CI students were matched with GHS EM clinical faculty and EM residents to investigate these topics: CPR training effectiveness, quantifying physician distractions, clinician decision making under fatigue, describing clinician physiologic biomarker variability during a shift, understanding the effect of consultant use on ED operations, and TB screening modeling.

Outcomes: Six teams incorporating 12 EM GHS faculty, 6 EM residents, 18 undergraduates, and 5 graduate students formed REEP to answer these 6 research questions over the course of a year. The teams generated 6 confirmed abstract conference presentations that secured a CU internal award of $6000 for dissemination.

Conclusion: REEP appears to have adapted the CU CI framework to produce promising scholarly work and expose nearly 2 dozen CU students to the health care environment this year. Future work will evaluate if these teams generate peer-reviewed manuscripts and track how many CU REEP participants pursue careers in health care.

Statin Shared Decision Making and Patient Education Study Brittany Kizer Stovall, Alexa Bianchi, and Meenu Jindal The 2013 American College of Cardiology/American Heart Association task force on practice guidelines demonstrated a new perspective focusing on atherosclerotic cardiovascular disease risk reduction from statins. With a paradigm move to patient-centered medicine, shared decision making (SDM) tools have created a collaborative way for medical decision making. One key question remains: Does SDM and use of an aid increase patientsâ&#x20AC;&#x2122; knowledge and continuation of taking statins?

The study population consisted of lower socioeconomic status, current statin use, and no known history of cardiovascular disease or coronary artery disease. The sample size was 27 individuals.

During their clinic visit, patients were asked to answer a survey regarding their knowledge of the mechanism of action, risks, and benefits of statins. Upon finishing the initial survey, patients then underwent an SDM session using the Mayo Clinic SDM Statin Aid. After the session, patients were asked to complete a postintervention survey. Scores of the initial and postintervention surveys were compared by paired t-test.

Two main areas were assessed: (1) the association between statin SDM aid and education, and (2) the impact on their decision to continue to take a statin. There was a 33% increase in patient education with a P value of < .001, along with a 94% willingness to continue to take their statin after the SDM. Therefore, SDM was shown to be effective for patient education; SDM should be encouraged and emphasized in academic training regardless of educational level or socioeconomic status.

Early Treatment Innovation for Opioid-Dependent Newborns: A Retrospective Comparison of Outcomes, Utilization, Quality, and Safety, 2006-2014 Julie Summey, Liwei Chen, Rachel Mayo, Elizabeth Charron, Jennifer Hudson, Windsor Westbrook Sherrill, and Lori Dickes Background: Few coordinated treatment programs address the needs of infants and families struggling with the effects of substance use. In 2003, Greenville Memorial Hospital launched the Managing Abstinence in Newborns (MAiN) program, providing multidisciplinary, coordinated, community-based care for neonatal abstinence syndrome (NAS). The aim of this study was to compare the 20

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SELECTED 2018 GHS RESEARCH SHOWCASE ABSTRACTS outcomes of MAiN infants to comparable NAS infants receiving traditional care between 20062014 in South Carolina.

Methods: De-identified sociodemographic and clinical data on MAiN infants, as well as NAS infants not treated with MAiN, were obtained from statewide databases in South Carolina. Study measures included medical and safety outcomes, health services use, child protective services involvement, emergency services utilization, and inpatient readmissions.

Results: We identified 110 infants who received the MAiN intervention and 356 SC NAS infants who were potentially MAiN-eligible. Overall, no significant differences existed in the two groups regarding medical or safety outcomes or child protective services involvement.

Traditional care NAS infants were more likely to be treated in a higher level nursery (69% vs. 0%).

MAiN infants had approximately $20 000 less per birth in average charges (P < .001) and an almost 5 days shorter length of stay (P < .001) than did the traditional care NAS infants. MAiN infants also had a lower percentage of ED visits (P = .01) assessed as possibly or likely NAS-related, as compared to traditional care NAS infants.

Conclusion: This study demonstrates the potential value of implementing the MAiN model in eligible NAS infants. Benefits of implementation may include significant cost reduction without sacrificing quality and safety.

New Public Health Partnership: GHS Emergency Department and SC DHEC HIV Surveillance Program Ben Theobald, Jackie Barnabe, and Phillip Moschella Purpose: To describe the implementation, relevance, and results of an emergency department (ED)based HIV surveillance system.

Methods and Results: South Carolina’s Department of Health and Environmental Control (DHEC) and Greenville Health System (GHS) have partnered to establish a program in which DHEC subsidizes “opt-out” HIV screening as performed on existing blood samples from individuals between the ages of 18-64 presenting to the ED with unknown HIV status. Newly diagnosed HIV-positive patients are then linked to initial treatment and follow up.

From Dec. 1, 2017-March 1, 2018, this program has tested 1123 individuals with 7 initial positives and 3 confirmed HIV diagnoses (0.26%). Of the remaining initial positive results, 2 were negative on confirmatory testing, and 2 others were previously diagnosed but were unknown in our medical record system.

Summary: HIV screening in the ED setting results in identification of undiagnosed individuals and successfully links them to treatment and follow up.

Clinical Relevance: Our program demonstrates how a government-supported, ED-based population health surveillance program can provide a positive impact on public health. With 30.2% of all HIV transmissions in the United States coming from undiagnosed individuals, the Office of National AIDS Policy set a goal that no more than 10% of HIV-positive patients in the this country remain undiagnosed. At present, that rate is 14% nationally and 16.6% in South Carolina, indicating a need for increased HIV surveillance. This program serves this purpose by identifying undiagnosed cases of HIV, subsequently decreasing HIV transmission rates and prevalence in South Carolina.

Cardiorespiratory Health, Muscular Strength/Endurance, and Fat-Free Mass Are Improved After 12 Weeks of Exercise Therapy in Cancer Survivors Jennifer Trilk, Ryan Porter, Noreen Denham, and W. Larry Gluck No studies to our knowledge have examined the effects of a nurse-supervised exercise program using certified cancer exercise trainers on anthropometric and physiologic variables in cancer survivors across multiple diagnoses.

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Purpose: To evaluate effects of Moving On, the Greenville Health System (GHS) Cancer Institute’s Oncology Rehabilitation program.

Methods: GHS oncologists referred eligible cancer survivors to Moving On (12 weeks, 1 hour, 3 days/ week of exercise therapy) after having completed initial chemotherapy or on maintenance chemotherapy and/or current radiation therapy. Baseline and follow-up evaluations included body mass index (BMI), body composition (body fat mass [FM], fat-free mass [FFM]), peak oxygen uptake (VO2 peak), muscle strength (1-repetition maximum [1-RM]), and muscle endurance (repetitions at 40% 1-RM).

Results: Survivors (N = 11, 54.5 ± 14.8 years of age; 82% women) who completed the program with ≥80% attendance were evaluated. No change in BMI or FM occurred; however, body FFM and truncal FFM increased 3.5% (3.3 lb, P = .02) and 3.8% (1.7 lb, P = .01), respectively. VO2 peak increased 20.2% (3.5 ± 0.9 ml/kg/min; P < .01), upper and lower body 1-RM increased 27.4% (24.8 ± 8.6 lb, P < .05) and 19.1% (35.8 ± 11.3 lb, P < .05), respectively. Upper- and lower-body muscular endurance increased 76.8% (+18.1 ± 1.9 repetitions, P < .001) and 76.3% (+13.7±2.8 repetitions, P = .001), respectively (absolute data reported as mean ± SE).

Conclusion: Cancer survivors across diagnosis groups and age ranges experienced anthropometric and physiologic benefits after taking part in Moving On. Applicability to Health Care: Standard-of-care for cancer survivors should include exercise therapy to help ameliorate the deleterious effects of cancer therapy and maximize return to function and quality of life.

Randomized Controlled Trial of a 4-week Mindfulness Intervention Among Cancer Survivors Michael Wirth, Regina Franco, Sara Wagner Robb, Katie Daniels, Kerri Susko, Matthew Hudson, and Mark O’Rourke Mindfulness-based practices encourage palliation through meditation, thus reducing stress and distress. This study examined a 4-week Mindfulness-Based Cancer Survivorship (MBCS) program among cancer survivors at Greenville Health System. Cancer survivor participants applied mindfulness practices to managing pain, fatigue, sleepiness, depression, and inflammatory and metabolic biomarkers. Investigators enrolled and randomized 40 cancer survivors to an intervention or control arm. The intervention group received a 4-week MBCS program with a 3-month follow-up postintervention. The control group received standard breathing exercises. Outcome measures assessed at baseline and 1-week postintervention included Pittsburg Sleep Quality Index (PSQI), Perceived Stress Scale (PSS), actigraphy data, and inflammation and metabolic biomarkers.

Analyses did not reveal any differences between intervention and control participants for the 4-week or 3-month time points. The intervention arm evidenced a reduction in sedentary hours at 4 weeks compared to baseline (-0.3 hours, P = .04). At the 3-month follow-up, the intervention participants significantly reduced their PSS (13.2 vs. 11.0, P = .06), PSQI score (8.1 vs. 6.3, P = .01), and sedentary hours (-1 hour, P = .03) compared to baseline. Their steps also increased by 1128 steps per day (P = .04). No changes were observed for biomarkers.

This study suggests that cancer survivors exposed to a mindfulness intervention report favorable changes to self-perceived stress, sleep quality, and physical activity. However, future research may identify potentially mediating factors such as dose of session, feasibility, and effectiveness among cancer patients. Additionally, future studies should consider enrolling more symptomatic patients to better evaluate effectiveness of such programs.

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GHS Proc. December 2018; 3 (1): 5-22

Special Article

Full List of Abstracts Presented at the 2018 GHS Health Sciences Center Research Showcase Best Overall Research Individual Human Galectin-9 Domains Display Distinct Antimicrobial Properties Anna Blenda, Nourine Kamili, Christian Gerner-Smidt, Anita Venkatesh, Connie Arthur, and Sean Stowell

Best Investigation of High-Value Care Project REVISE—The Impact at GHS Elizabeth Tyson, Karen Eastburn, Jeremiah Smith, and Kevin Polley

Best Investigation of Patient Engagement Integrating Personalized Patient Goals and Priorities Into Clinical Care Melanie Cozad, Gulzar Merchant, Rasmine Baker, and Kait Crosby

Best Investigation of Diabetes JUMPing Into Diabetes Control Lauren Hassan, Sheena Henry, Gail Chastain, and Meenu Jindal

Best Investigation of Population Health Improving Population Health Through Hypertension Control Susan Sutherland, Brent Egan, Robert Davis, David Ramsey, and Robert Hanlin

Early Investigator’s Award Antibiotic Irrigation of the Surgical Site Decreases Incidence of Surgical Site Infection After Open Ventral Hernia Repair Lily Fatula, Allison Foster, Hamza Abbad, Joseph Ewing, Ben Hancock, William Cobb, Alfredo Carbonell, and Jeremy Warren

Best Medical Student Research Pneumatic Dilation Improves Esophageal Emptying on Timed Barium Esophagram in Patients With Esophago-Gastric Junction Outflow Obstruction Claire Shin, Wojciech Blonski, Joseph Ewing, Joel Richter, and Steven Clayton

Best Nursing Student Research Bioelectrical Impedance Analysis Accuracy: Factors That Affect Test Results Maeve Murphy, Brandi Ingram, Sarah Feus, and Jillian Robert Factors Affecting Salvage Rate of Infected Prosthetic Mesh Hamza Abbad, Benjamin Hancock, William Cobb, Alfredo Carbonell, and Jeremy Warren Fine Needle Aspiration vs. Gencut Core: Is One Biopsy Method Superior in Terms of Tissue Volume?

Tiffanie Aiken, Allyson Hale, Joseph Ewing, William Bolton, James Stephenson, and Sharon Ben-Or

GHS Proc. December 2018; 3 (1): 23-28

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Volumetric Analysis of Patients Undergoing Abdominal Wall Reconstruction After Preoperative Progressive Pneumoperitoneum John Allen, Jeremy Warren, and Joseph Bittle The Clinical and Economic Impact of a Physical Activity-Based Treatment Program for Severe Obesity Irfan Asif, Joseph Ewing, Samantha Reid, Nathan Schewecke, Allyson Hale, Vicki Nelson, and Michael Wiederman Comparison of Electrocardiographic Interpretation Criteria for Use in Athlete Screening Elizabeth Barton, Vicki Nelson, Joseph Ewing, Brett Toresdahl, Jonathan Drezner, and Irfan Asif Understanding Pedal Usage and Foot Movement Characteristics of Older Drivers Leah Belle, Yubin Xi, Johnell Brooks, Paul Venhovens, Shayne McConomy, John DesJardins, Patrick Rosopa, Kevin Kopera, Constance Truesdail, Nathalie Drouin, Sarah Hennessy, Stephanie Tanner, Jeremy McKee, and Kathy Lococo Assessing Barriers to Implementing Shared Decision Making Alexa Bianchi, Brittany Crum, and Meenu Jindal Early Warning Response System in GHS School-Based Health Centers Holly Bryan, Laura Rolke, Sarah Griffin, Jacqueline Forrester, Laura Johnson, and Kerry Sease An Integrated Passive Strain Sensor for Dynamic Hip Screws to Monitor Intertrochanteric Fracture Stability with Radiography Nathan Carrington, Bryce Kunkle, Caleb Behrend, Tom Pace, Paul Millhouse, Jeffrey Anker, and John DesJardins Construction of Chimeric Histone Methyltransferase Complexes in Saccharomyces cerevisiae Generates Unique Phenotypes and Clarifies the Roles of MLL1 and Set1 Complex Accessory Proteins Renee Chosed, Arnav Lal, David Klein, Emery Longan, Marian Baker, Sasha Gogoli, Jingtian Wang, and Sami Alkoutami Exercise Programming Correlates With Patient Success in a Comprehensive Pediatric Weight Loss Program Jenna Crowder, Irfan Asif, Cara Reeves, Kerstin Blomquist, Erin Brackbill, Sarah Griffin, Dorothy Schmalz, Kerry Sease, Laure Utecht, and Vicki Nelson Supportive Care Metrics for a Community Oncology AYA Program Elizabeth Cull, John McAlhany, Sarah Taylor, Heather Bowers, Kerri Susko, and Aniket Saha Beyond Bates: Advanced Physical Exam Series for Medical Students Ryan Dean and Steven Connelly Analysis of Positive Responses to 2 Different Heart Health Questionnaires in NCAA Division 1 Athletes Joseph DeStefano, Hampton Williams, Douglas Reeves, Joseph A. Ewing, and Irfan M. Asif Evaluation of CarFit Criteria Compliance and Knowledge of Seat Adjustment Nathalie Drouin, Shayne McConomy, Johnell Brooks, Paul Venhovens, Yubin Xi, Patrick Rosopa, John DesJardins, Kevin Kopera, Leah Belle, Connie Truesdail, Stephanie Tanner, Kathy Lococo, Loren Staplin, and Elin Schold Davis

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GHS Proc. December 2018; 3 (1): 23-28

FULL LIST OF 2018 GHS RESEARCH SHOWCASE ABSTRACTS Model for Management of Medicare Patients With Congestive Heart Failure and Multiple Chronic Conditions Brent Egan, Joel Amidon, Bruce Hanlin, and Irfan Asif Geographic Variation in the Treatment of Proximal Humerus Fracture in the Medicare Population Sarah Floyd, Joel Campell, Charles Thigpen, Mike Kissenberth, and John Brooks Persistent Functional Neurological Symptom Disorder Spontaneously Remits With ECT Treatment Raphaela Fontana, Frank Clark, and Benjamin Griffeth Optimization of Automated Guided Vehicle System in Health Care Facility Kade Gilstrap, Amogh Bhosekar, Tugce Isik, Sandra Eksioglu, and Robert Allen Improving Quality to Facilitate Research Amanda Goode, Katie Daniels, and Matthew Hudson The Correlation Between Residency Applications and Standardized Behavioral Assessments for Gaining Entry Into a Graduate Medical Education Program Vincent Green and Ardalan Ahmadi Self-Perceptions on Fitness to Drive in Collegiate Athletes Following a Sport-Related Concussion Steven Greene, Yathavan Rajakulasingam, Vicki Nelson, Alex Ewing, and Andrew Albano Wearable Motion Quantification and Electronic Diaries for Long-Term Monitoring of Parkinson’s Disease Aaron Hadley, Enrique Urrea Mendoza, Nicola Mennucci, Carol Zimmerman, Joseph Giuffrida, Zoltan Mari, Michelle Burack, Ilia Itin, Fredy Revilla, and Dustin Heldman Micromotion and Strength of the Glenoid Component in Reverse Total Shoulder Arthroplasty Shannon Hall, David Baxley, Michael Kissenberth, Josh Karnes, Nick Metcalfe, and John DesJardins Identifying the Profile of Youth Who Present to the Emergency Department for Psychiatric Reasons Sharon Holder, Dawn Blackhurst, and Eunice Peterson Biomechanical Effects of Therapeutic Horseback Riding on Balance and Gait Confidence in the Elderly Anne Marie Holter, Julia Gates, John DesJardins, Kristine Vernon, and Marieke Van Puymbroeck Are We Asking the Right Questions? Screening and Counseling for Environmental Tobacco Smoke Exposure at a Federally Qualified Health Center Elizabeth Holt, Jackson Pearce, McKenna Luzynski, Matthew Delfino, and Lochrane Grant The Effect of Fad Diets on Patients’ Perceptions of Health and Disease Cassidy Hood, Robert Masocol, Alex Ewing, Vicki Nelson, and Irfan Asif Potential Benefits of a Separate Instrument Setup Room or Induction Room Adjacent to the Operating Room Brandon Lee, Dee San, Kevin Taaffe, Lawrence Fredendall, Yann Ferrand, Amin Khoshkenar, Alexis Fiore, Anjali Joseph, and Scott Reeves

GHS Proc. December 2018; 3 (1): 23-28

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Leader Mindfulness, Unit Well-Being, and Patient Care Chelsea LeNoble, Michelle Flynn, Marissa Shuffler, Nastassia Savage, Sharon Wilson, and Tod Tappert Implementation of the Survey of Well-Being of Young Children (SWYC) Form in a Primary Care Office to Improve Screening of Children 2 Months to 5 Years of Age Eric Lessard and Sara Ryder Emerson Influence of Opioid Referrals on Physical Therapy Outcomes for Patients with Neck and Back Pain K. Markut, D. Dunn, A. Lutz, T. Denninger, E. Shanley, M. Kissenberth, and C. Thigpen Understanding How Clinicians Use Epic in Clinical Practice: A Time and Motion Study Benjamin Martin, Mark Wess, Nicholas Perkins, Renee Tollison, and Ronald Gimbel Evaluation of Chronic Lung Disease and Surgical Retinopathy of Prematurity Outcomes After a Change to Bubble Continuous Airway Pressure Ara Messamer, Reese Clark, and Felecia Wood Cervical Interbody Spacer with Passive Radiographic Fusion Status Indicator Paul Millhouse, Md Arifuzzaman, Apeksha Rajamanthrilage, Nathan Carrington, Caleb Behrend, John DesJardins, and Jeffrey Anker Interdisciplinary Care Huddles and Rounding Christy Morris, Terri LaRusso, Annette Dunphy, and Paari Gopalakrishnan Increasing Compliance With Consistent Sterile Procedure During Central Line Fluid Changes in the Small Baby Unit of the Neonatal ICU to Decrease the Central Line-Associated Bloodstream Infection (CLABSI) Rate Melissa Motes and Michael Stewart Two-Year Retest Variability of ImPACT Baseline Concussion Testing in High School Athletes Vicki Nelson, Irfan Asif, Kyle Cassas, J. Brandon Harris, J. Aldrin Enabore, and W. Franklin Sease Jr. On the Path to Total Knee Arthroplasty Alicia Oostdyk, Noor Alshareef, Rasmine Baker, Melanie Cozad, Sarah Floyd, and Paul Siffri Can Commercially Available Voice Prompting Automated External Defibrillators (AEDs) Be Utilized Effectively by Grade School Children?

Sally Peterson, Phillip Moschella, Amy Ramsay, and Dotan Shovrin Reducing Burnout and Improving Meaningful Work Through Medical Resident Poverty Simulation: A Pilot Study Camiron Pfennig and Chelsea LeNoble Initiation of an Osteoporosis Treatment Program at Our Institution Drew Ratner, Billy Clark, Amy Trammell, Laura Boineau, and Kyle Jeray To Develop an Inexpensive, but Versatile Device to Elevate the Field of Point-of-Care Clinical Analysis Paige Reed, Jeff Edenfield, and Carlos D. Garcia Leveraging Electronic Health Record Data to Improve Diabetes Control and Prevention: The DART Quality Improvement Program Sara Sarasua, Kim Roberts, Susan Sutherland, Robert Davis, David Ramsey, C. Shaun Wagner, and Brent Egan 26

GHS Proc. December 2018; 3 (1): 23-28

FULL LIST OF 2018 GHS RESEARCH SHOWCASE ABSTRACTS Employing the Patient-Centered Collaborative Care Approach Joel Saul, Sharon Holder, and Jonathan Lokey Caring for Caregivers: Identifying Personality Risk Factors in Burnout Development Nastassia Savage, Zachary Klinefelter, Marissa Shuffler, Camiron Pfennig, and Ronald Pirrallo Impact of an Alert Reduction Strategy on Pharmacist Alert Override Rates Within a Clinical Decision Support System John Schoonover, Becky Sawyer, Lucy Crosby, Alyson Ghizzoni-Burns, and Jun Wu Using Epic to Measure Referral Rates by Greenville Health System Pediatricians to Developmental and Behavioral Support Services Megan Schmalz, Julia Moss, Jacqueline Forrester, Sarah Griffin, Christopher Wilson, and Kerry Sease Stability of Parkinsonâ&#x20AC;&#x2122;s Disease Subtypes Based on a Cluster Analysis in a Large Cohort Artur Schumacher-Schuh, Oswaldo Lorenzo-Betancor, James Leverenz, Liana Rosenthal, Ted Dawson, Marilyn Albert, Zbigniew Wszolek, Owen Ross, Dennis Dickson, Joseph Quinn, Kathryn Chung, Amie Peterson-Hiller, Alberto Espay, Johnna Devoto, Fredy Revilla, Jennifer Goldman, Glenn Stebbins, Bryan Bernard, Tom Montine, Cyrus Zabetian, and Ignacio Mata Comparing Telephone-Based Diabetes Education to Resident Clinic Standard of Care in Uncontrolled Type 2 Patients With Diabetes Henry Schwartz, Caroline Clary, Gail Chastain, and Meenu Jindal Comparison of High- vs. Low-Fidelity Simulation Models for AHA CPR Training in Middle School Students Bijal Shah, David Wong, Sally Peterson, Phillip Moschella, Amy Ramsay, and Dotan Shvorin Return to Sport as Outcome Measure for Shoulder Instability Ellen Shanley, Charles Thigpen, Lauren Ruffrage, Douglas Wyland, Michael Kissenberth, and John Tokish Assessing an Exercise Vital Signs in Pediatric Patients Emily Sherrard, Robert Masocol, Irfan Asif, J. Alex Ewing, and Vicki Nelson Critical Social Thinking and Mindfulness Skills as Levers for Facilitating Health Care Unit Engagement and Unit Climate for Patient Safety Marissa Shuffler, Chelsea LeNoble, Michelle Flynn, Dana Verhoeven, Nastassia Savage, Pamela Farago, Tiffany Cooper, Sharon Wilson, and Terrie Long Strategic Development of a Research Experience Enrichment Program (REEP) in the Emergency Medicine Department Dotan Shvorin, Ronald Pirrallo, Kevin Taaffe, and Phillip Moschella Statin Shared Decision Making and Patient Education Study Brittany Kizer Stovall, Alexa Bianchi, and Meenu Jindal Early Treatment Innovation for Opioid-Dependent Newborns: A Retrospective Comparison of Outcomes, Utilization, Quality, and Safety, 2006-2014 Julie Summey, Liwei Chen, Rachel Mayo, Elizabeth Charron, Jennifer Hudson, Windsor Westbrook Sherrill, and Lori Dickes Reduction in Type 2 Diabetes Markers With Longer Duration of Breastfeeding in the Peri/ postnatal Epigenetic Twins Study (PETS): Theoretical Epigenetic Mechanisms Heide Temples, Yuk Jing Loke, William Bridges, Richard Saffery, and Jeffrey Craig GHS Proc. December 2018; 3 (1): 23-28

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New Public Health Partnership: GHS Emergency Department and SC DHEC HIV Surveillance Program Ben Theobald, Jackie Barnabe, and Phillip Moschella Cardiorespiratory Health, Muscular Strength/Endurance and Fat Free Mass Are Improved After 12 Weeks of Exercise Therapy in Cancer Survivors Jennifer Trilk, Ryan Porter, Noreen Denham, and W. Larry Gluck Using X-ray Excited Luminescent Chemical Imaging (XELCI) to Image Changes in pH on the Surface of Implanted Medical Devices in Order to Detect and Monitor ImplantAssociated Infection Unaiza Uzair, Donald Benza, Fenglin Wang, Yash Raval, Tzuen-Rong Tzeng, Caleb Behrend, and Jeffrey Anker White Coat Syndrome in the Obese Pediatric Population: The Case for Ambulatory Blood Pressure Monitoring Scott Walters, Ransome Eke, Hannah Kline, Shane Sundlie, Kerry Sease, and Jonathan Markowitz Prophylactic Placement of Permanent Synthetic Mesh at the Time of Ostomy Closure Prevents Incisional Hernia Formation Jeremy Warren, Lucas Beffa, Alfredo Carbonell, Jennifer Cull, Brent Sinopoli, Joseph Ewing, Cedrek McFadden, Jay Crockett, and William Cobb Randomized Controlled Trial of a 4-week Mindfulness Intervention Among Cancer Survivors Michael Wirth, Regina Franco, Sara Wagner Robb, Katie Daniels, Kerri Susko, Matthew Hudson, and Mark O’Rourke Immediate and Delayed Retention of Stroke and Healthy Lifestyle Education Among Middle School Students Leah Wormack, Jordan Gainey, Amber Frazier, Chibueze Ubah, Chloe Gonzalez Jackson, Anita Venkatesh, Natalia Rincon, Leanne Brechtel, Brantley Dick, Megan Fredwall, Jennifer Cook, Sarah Konklin, Vivek Venkatesh, and Thomas Nathaniel

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GHS Proc. December 2018; 3 (1): 23-28

Miscellany

2018 GHS Residents and Fellows Family Medicine Joel Rhein Amidon, MD Mohamed Balout, MD Courtney Lynn Duffy, MD Sheelah Orinion Gervacio, MD Eric Lessard, MD Laura Mary Morrison, MD Primary Care Sports Medicine Elizabeth Eleanor Barton, MD Jenna Lynn Crowder, MD General Surgery MacKenzie Johanna Bartz, MD William John Berglind, MD Kyle Vernon Conway, MD Ashley Jana Marie Jones, MD Sean Patrick McGrath, MD Katherine Ferstadt Pellizzeri, MD Minimally Invasive Surgery John Michael Allen, MD David Gregory Pearson, MD Vascular Surgery Brian Michael Freeman, MD Jonathan Jay Sexton, MD Internal Medicine Mary Crouse Blumer, MD Caroline Rebecca Clary, MD Bonnie Elizabeth DeBusk, DO Michael Joseph Haden, MD Sheena Marie Henry, MD John John, MD

GHS Proc. December 2018; 3 (1)

Catherine Lea Morris, MD Rachel Anne Quaney, MD Kerolos George Rizk, DO Laura Emily Roache, DO Henry Vernon Schwartz III, MD Ashton Scott Townsend, DO

Internal Medicine/Pediatrics Craig Michael Anderson, MD Marla Turner Chapman, MD Clay Martin Crosby, MD Katie Lauren Mclemore McQueen, MD Dennis Ryan Paulk, MD Obstetrics & Gynecology Laura Dopson Almquist, MD Charis Nailah Chambers, MD Kelly Whittaker Kline, MD Lauren Jamison Pinckney, MD Katie Mellington Vemireddy, MD Andrew James White, MD Orthopaedic Surgery Aneel Kumar Jiwanlal, MD Michael Robert Koerner, MD Mark Christian Daniel Moody, MD Drew Alan Ratner, MD Orthopaedic Sports Medicine Joel Robert Campbell, MD John Larson Glomset, MD Ryan Stephenson Rowland, MD Lane Nicholas Rush, MD

Adult Reconstruction Surgery Nicholas Miladore, MD Pediatrics Eric Michael Bankert, DO Meghan Skinner Jordan, MD Lindsey Brianne McAmis Gouge, MD Matthew Christopher McGee, MD Ashtin Danielle Nix, MD Colton Lee Ragsdale, MD Christine Nabil Riyad, MD Andreea Iulia Stoichita, MD Grace Ann Twitty, MD John Robert Winningham, MD Victoria Lynnette Winningham, MD Developmental-Behavioral Pediatrics Steven Hsiang-Yu Ma, MD Pharmacy Alyssa Marie Gaietto, PharmD Christopher Michael Nappi, PharmD Amy S. Robinson, PharmD John Hunter Schoonover, PharmD Allyson Sleeman, PharmD Patrick D. Walker, PharmD Brittany M. Wills, PharmD Psychiatry Lisa Bush Bostic, MD Ryan Ashley Greene, MD Nahid Nadiri, MD Andrew J. Ruege, MD Joel Robert Saul, DO

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Miscellany

USC School of Medicine Greenville Class of 2018 Alyssa Adkins Kenzie Alexander Carly Atwood Bobby Baranello Janet Basinger Leighann Black Joey Blackwell Ethan Brown Andrew Buhr Stefano Cardin Pozo Krupesh Dave Raquel Denis Phillips DeRidder Catherine Entriken Hannah England David Erazo Brian Fazzone Alicia Firestone Tim Fletcher Megan Fredwall Jordan Gainey Anne Marie Gerstner Taylor Girolamo Kalie Goodman Mike Granade

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Scott Griffin Tee Griscom Wes Hardgrove Harry Hicklin Cody Hill Michael Hood Meghan Hudak Stephen Hudson Eleasa Hulon Calley Huntsinger Sven Ivankovic Brian Jones Matt Kerr Hannah Kline Brittany Lamont Alex Lea Andrew Lee William Lightle Jordan Malray Whitney Mayberry Katrina Morgan Gabrielle Morris Wes Parker Shuler Polk Ben Ramsey

Natalia Rincon Julia Robison Greg Roop Taylor Rozier Ella Shreder Hannah Shull Jasmine Smith Noah Smith Crystal Sosa Grace Spencer Mark Spencer Hope Sprunger Clay Stafford Bianca Stewart Shane Sundlie Andrew Swartz Nate Teague Lauren Ashley Tipton Mary Van Wert Casey Wang Shannon Wentworth Jeremiah White Jessica-Ashley Williams Bailey Wooten Sara Yi

GHS Proc. December 2018; 3 (1)

Miscellany

2018 Publications of Greenville Health System Medical and Scientific Staff Emergency Medicine 1.

Baird M, Asif I. Medications helpful for changing sleep schedules in athletes. Sports Health. 2018;10(1):31-5.

2.

Bitner ME, Benjamin L, Farris SR. Clinical learning in an urban emergency department: an examination of residentsâ&#x20AC;&#x2122; abilities for reflective practice. GHS Proc. 2017;2(2):115-24.

3.

Brown PA, Shah B. Emerging treatment options for acute lymphoblastic leukemia: focus on CAR T-cell therapy. J Natl Compr Canc Netw. 2018;16(5S):651-5.

4.

Burton E, Stanley M. SIRS criteria: a nidus for bias and how to minimize it. EM Resident Magazine. 2018;45(1):22-3.

5.

Callaway DW, Puciaty A, Robertson J, Hannon T, Fabiano SE. Case report: life saving application of commercial tourniquet in pediatric extremity hemorrhage. Prehosp Emerg Care.

2017;21(6):786-8.

6.

Chan T, McColl T, Luckett-Gatopoulos S, Purdy E, Eicken JJ. Medical education in cases.

In: Thoma B, ed. Academic Life in Emergency Medicine. 1st ed. San Francisco, CA. 2017;3(1).

7.

Chou A, Brevil A, Eicken JJ. Use of point-ofcare ultrasound to measure hematoma volume.

Vis J Emerg Med. 2017;8:44-5.

8.

Del Vecchio A, Pfennig CL, Moschella PC. 84 medical student response to improvisation and acting training: novel curriculum pilot study.

Ann Emerg Med. 2017;70(4):S34-5.

9.

Faul M, Lurie P, Kinsman JM, Dailey MW, Crabaugh C, Sasser S. Multiple naloxone administrations among emergency medical service providers is increasing. Prehosp Emerg Care. 2017;21(4):411-9.

10. French DM, Bridges EP, Hoskins MC, Andrews CM, Nelson CH. Myasthenic crisis in pregnancy. Clin Pract Cases Emerg Med. 2017;1(4):291-4.

11. Gimbel RW, Pirrallo RG, Lowe SC, Wright DW, Zhang L, Woo MJ, Fontelo P, Liu F, Con-

GHS Proc. December 2018; 3 (1): 31-46

nor Z. Effect of clinical decision rules, patient cost and malpractice information on clinician brain CT image ordering: a randomized controlled trial. BMC Med Inform Decis Mak. 2018;18(1):20.

12. Hanlin RB, Asif I, Wozniak G, Sutherland SE, Shah B, Yang J, Davis RA, Bryan ST, Rakotz M, Egan BM. Measure Accurately, Act Rapidly, and Partner With Patients (MAP) improves hypertension control in medically underserved patients: Care Coordination Institute and American Medical Association Hypertension Control Project Pilot Study results. J Clin Hypertens. 2018;20(1):79-87.

13. Ko C, Baird M, Close M, Cassas KJ. The diagnostic accuracy of ultrasound in detecting distal radius fractures in a pediatric population.

Clin J Sport Med. 2017;1. PMID: 29189342.

14. Loberger J, Sharp J, Polley KA. Implementation of a clinical management pathway to shorten time to antibiotic delivery in febrile patients with sickle cell disease in a pediatric emergency department. GHS Proc.

2017;2(2):137-43.

15. Pfennig CL, Slovis C. Electrolytes. In: Walls R, Hockberger R, Gausche-Hill M, eds.

Rosenâ&#x20AC;&#x2122;s Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier, 2017;1516-32.

16. Pinto L, Lein A, Mahoque R, Wright DW, Sasser S, Staton CA. A cross-sectional exploratory study of knowledge, attitudes, and practices of emergency health care providers in the assessment of child maltreatment in Maputo, Mozambique. BMC Emerg Med. 2018;18(1):11.

17. Polk R, Blackhurst DW, Moschella PC. 392 disposition destination does not affect patient experience ratings in real-time in an urban academic emergency department. Ann Emerg Med. 2017;70(4):S153-4.

18. Taylor R, Blackhurst DW, Moschella PC. 361 patient experience scores are affected by timing of survey administration in an urban

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academic emergency department. Ann Emerg Med. 2017;70(4):S142-3.

19. Vandervall K, Yehl MA, Tjiattas-Saleski L. Paronychia. Osetopath Fam Physician.

2018;10(1):23.

20. Warren J, Stoddard C, Hunter AL, Horton AJ, Atwood C, Ewing JA, Pusker S, Cancellaro VA, Walker KB, Cobb W, Carbonell A, Morgan RR. Effect of multimodal analgesia on opioid use after open ventral hernia repair. J Gastrointest Surg. 2017;21(10):1692-9.

21. Weinmeister KL, Lerner EB, Guse CE, Ateyyah KA, Pirrallo RG. Dispatcher CPR instructions across the age continuum. Prehosp Disaster Med. 2018;33(3):342-5.

22. Williams S, Nelson R, Kashif R, Goff T, Simon L, Janse MC. Demographic variation in the injury patterns of adult cyclists admitted to a large US healthcare network: a five-year review. Trauma. 2017; DOI: 10.1177/1460408617740903.

Family Medicine 23. Asif I, Ewing JA, Reid S, Schewecke N, Hale A, Nelson V, Wiederman M. Clinical and economic impact of a physical activity-based wellness program to treat severe obesity: 2-year follow-up. Clin J Sport Med. 2018;28(2):239-48.

24. Barton E, Nelson V, Asif I. Chest pain and palpitations â&#x20AC;&#x201C; lacrosse. Med Sci Sports Exerc.

2018;50(5):124.

25. Barton E, Nelson V, Ewing JA, Asif I. Comparison of electrocardiographic interpretation criteria for use in athlete screening. Clin J Sport Med. 2018;28(2):239-48.

26. Crowder J, Sease WF, Asif I, Nelson V. Painful arm mass â&#x20AC;&#x201C; weight lifting. Med Sci Sports Exerc. 2018;50(5):124.

27. Egan BM, Sutherland SE, Rakotz M, Yang J, Hanlin RB, Davis RA, Wozniak G. Improving hypertension control in primary care with the Measure Accurately, Act Rapidly, and Partner with Patients protocol results at 5 and 12 months. Hypertension. 2018;72:1320-7.

28. Goode AP, Taylor S, Hastings SN, Stanwyck C, Coffman CJ, Allen KD. Effects of a home-based telephone-supported physical activity program for older adult veterans with chronic low back pain. Phys Ther. 2018;98(5):369-80.

29. Gunn AH, Schwartz TA, Arbeeva LS, Callahan LF, Golightly Y, Goode A, Hall CH, Huffman K, Iversen MD, Pathak A, Taylor S, Allen KD. The frequency of and patient characteristics associated with fear of movement in adults with

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symptomatic knee osteoarthritis. Arthritis Care Res. 2017;69(12):1826-33.

30. Mitchell-Bennett L, Zolezzi M, LuBeth P, Saldana M, Vatcheava K, Meyer L, Patterson SF, Reininger B. Coordinated care beyond clinical settings for patients with uncontrolled diabetes. Published online Nov 2017 as part of the American Public Health Association Annual Meeting, Atlanta, GA. 31. Nelson V, Masocol RV, Ewing JA, Wiederman M, Asif I. Associations between the physical activity vital sign and cardiometabolic disease in high-risk pediatric patients. Med Sci Sports Exerc. 2018;50(5):202.

32. Nelson V, Rao A, Sease WF, Shanley E, Asif I. Hazing prevalence and perceptions among collegiate athletes. Clin J Sport Med. 2018;28(2):184-230.

33. Nelson V, Sease WF, Cassas KJ, Harris B, Enabore JA, Asif I. Two-year retest variability of ImPACT baseline concussion testing in high school athletes. Clin J Sport Med. 2018;28(2):239-48.

34. Nelson V, Masocol RV, Ewing JA, Johnston S, Hale A, Wiederman M, Asif I. Association between a physical activity vital sign and cardiometabolic disease in high-risk patients. Clin J Sport Med. 2018;PMID: 29601348.

35. Taylor S, Oddone EZ, Coffman CJ, Jeffreys AS, Bosworth HB, Allen KK. Cognitive mediators of change in physical functioning in response to a multifaceted intervention for managing osteoarthritis. Int J Behav Med. 2018;25(2):162-70.

36. Taylor S, Hughes JM, Coffman CJ, Jeffreys AS, Ulmer CS, Oddone EZ, Bowsorth HB, Yancy WS, Allen KD. Prevalence of and characteristics associated with insomnia and obstructive sleep apnea among veterans with knee and hip osteoarthritis. BMC Musculoskelet Disord.

2018;19(1):79.

Medicine 37. Akiyama MJ, Feffer R, von Oehsen WH, Litwin AH. Drug purchasing strategies to treat people with hepatitis C in the criminal justice system.

Am J Public Health. 2018;108(5):607-8.

38. Akiyama M, Macdonald R, Jordan A, Columbus D, Schwartz J, Litwin AH, Eckhardt B, Carmody E. Linkage to HCV care and reincarceration following release from New York City jails. J Hepatol. 2018;68(suppl 1):S175-6.

39. Akiyama MJ, Agyemang L, Arnsten JH, Heo M, Norton BL, Schackman BR, Linas BP, Litwin AH. Rationale, design, and methodology of a

GHS Proc. December 2018; 3 (1): 31-46

2018 PUBLICATIONS trial evaluating three models of care for HCV treatment among injection drug users on opioid agonist therapy. BMC Infect Dis. 2018;18(1):74.

40. Andorsky D, Coleman M, Yacoub A, Melear JM, Brooks HD, Fanning SR, Kolibaba KS, Lansigan F, Reynolds C, Li J, Liu D, Llorente M, Ricker JL, Sharman JP. Response rate to lenalidomide plus rituximab (R2) as independent of number of prior lines of therapy: interim analysis of initial phase of MAGNIFY phase IIIb study of R2 followed by maintenance in relapsed/refractory indolent NHL. J Clin Oncol. 2018;36(suppl 15):7516.

41. Batchelder AW, Cockerham-Colas L, Peyser D, Reynoso SP, Soloway I, Litwin AH. Perceived benefits of the hepatitis C peer educators: a qualitative investigation. Harm Reduction J. 2017;14(1):67.

42. Bhullar P. Tracking patients in community-based palliative care through the Centers for Medicare and Medicaid Services Healthcare Innovation Project. J Palliat Med. 2017;20(11):1231-6.

43. Callahan SP, Tanner NT, Chen A, Macro T, Silvestri GA, Pastis NJ. Comparison of the thin convex endobronchial ultrasound bronchoscope to standard endobronchial ultrasound and flexible bronchoscope. US Resp Pulm Dis. 2017;2(1):33-6.

48. Edenfield WJ, Martin JC, O’Rourke MA, Cull E, Chung K. Improving care delivery for patients with rare cancers: a phase II trial of durvalumab in combination with tremilumimab in subjects with advanced rare tumors in a large community health care system. J Clin Oncol. 2018;36(suppl 15):e18535.

49. Egan BM, Li J, Sarasua SM, Davis RA, Fiscella KA, Tobin JN, Jones D, Sinopoli A. Cholesterol control among uninsured adults did not improve from 2001-2004 to 2009-2012 as disparities with both publicly and privately insured adults doubled. J Am Heart Assoc.

2017;6(11):e006105.

50. Escalona Villasmil, P, Siegel, RD. Diet and nutrition in the treatment of prediabetes and diabetes. Scientific American Medicine. In: Robinson MK, ed. Hamilton (ON): Decker Intellectual Properties, Apr 2018. DOI: 10.2310/7900.9033.

51. Forero-Torres A, Ramchandren R, Yacoub A, Edenfield WJ. Results from a phase ½ study of INCB050465, a highly selective and highly potent PI3Kδ inhibitor in patients with relapsed or refractory B-cell malignancies (CITADEL-101). Blood. 2017;130.

44. Cheung EM, Edenfield WJ, Mattar B, Anthony SP, Mutch PJ, Chanas B, Smith MJ, Hepner A. Safety and pharmacokinetics of bendamustine rapid-infusion formulation. J Clin Pharmacol.

2017;57(11):1400-8.

52. Fullard ME, Thibault DP, Hill A, Fox J, Bhatti DE, Burack MA, Dahodwala N, Haberfeld E, Kern DS, Klepitskava OS, Urrea-Mendoza E, Myers P, Nutt J, Rafferty MR, Schwalb JM, Shulman LM, Willis AW. Utilization of rehabilitation therapy services in Parkinson disease in the United States. Neurology.

2017;89(11):1162-9.

45. Conway B, Dore G, Altice F, Litwin AH, Grebely J, Dalgard O, Gane E, Shibolet O, Luetkemeyer A, Nahass R, et al. A172 C-edge co-star: risk of reinfection following successful therapy with elbasvir (EBR) and grazoprevir (GZR) in persons who inject drugs (PWID) receiving opiod agonist therapy (OAT). J Can Assoc Gastroenterol. 2018;1(suppl 1):299-300.

53. Gambacorti-Passerini C, Orlov S, Zhang L, Braiteh F, Huang H, Esaki T, Horibe K, Ahn JS, Beck JT, Edenfield WJ, Shi Y, Taylor M, Tamura K, Van Tine BA, Wu SJ, Paolini J, Selaru P, Kim TM. Long-term effects of crizotinib in ALK-positive tumors (excluding NSCLC): a phase 1b open-label study. Am J Hematol.

2018;93(5):607-14.

46. Deming R, Ford MM, Moore MS, Lim S, Perumalswami P, Weiss J, Wyatt B, Shukla S, Litwin AH, Reynoso S, et al. Evaluation of a hepatitis C clinical care coordination program’s effect on treatment initiation and cure: a surveillance-based propensity score matching approach. J Viral Hepat. 2018;25(11):1236-43.

54. Gambacorti-Passerini C, Orlov S, Zhang L, Edenfield WJ. Safety and efficacy of crizotinib in ALK-positive lymphomas: a phase 1b open-label study. Blood. 2017;130:4128.

47. Dirix LY, Takacs I, Edenfield WJ, et al. Avelumab, an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: a phase 1b JAVELIN Solid Tumor study.

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55. Gluck WL, Martin JC, Edenfield WJ, Chung K, Arguello D. Prolonged response of widely metastatic HER2-positive colon cancer to trastuzumab therapy. Colorectal Cancer.

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57. Grebely J, Dalgard O, Conway B, Cunningham EB, Bruggmann P, Hajarizadeh B, Amin J, Bruneau J, Hellard M, Litwin AH, Marks P, Quiene S, Siriragavan S, Applegate TL, Swan,T, Byrne J, Lacalamita M, Dunlop A, Matthews GV, Powis J, Shaw D, Thurnheer MC, Weltman M, Kronborg I, Cooper C, Feld JJ, Fraser C, Dillon JF, Read P, Gane E, Dore GJ. Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial. Lancet Gastroenterol Hepatol. 2018;3(3):153-61.

58. Grebely J, Bruneau J, Lazarus JV, Dalgard O, Bruggmann P, Treloar C, Hickman M, Hellard M, Roberts T, Crooks L, Midgard H, Larney S, Degenhardt L, Alho H, Byrne J, Dillon JF, Feld JJ, Foster G, Goldberg D, Lloyd AR, Reimer J, Robaeys G, Torrens M, Wright N, Maremmani I, Norton BL, Litwin AH, Dore GJ. Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs. Int J Drug Policy. 2017;47:51-60.

59. Guo Q, Shuford S, McKinley B, Rippon M, Cornett W, O’Rourke MA, Schammel DP, Edenfield J, Kaplan DL, Crosswell HE, DesRochers T. 3D modeling of immune cell interactions in breast cancer and prediction of immunotherapy response. Cancer Res. 2017;77(suppl 13):4834.

60. Hakimi R, Hierholzer S. Aorto-tracheo/pulmonic fistula from squamous cell carcinoma leading to cerebral air embolism. Published online March 2018 as part of the American Society of Neuroimaging Annual Meeting, Austin, TX. DOI: org/10.1111/jon.12507.

61. Hanlin RB, Asif I, Wozniak G, Sutherland SE, Shah B, Yang J, Davis RA, Bryan ST, Rakotz M, Egan BM. Measure Accurately, Act Rapidly, and Partner With Patients (MAP) improves hypertension control in medically underserved patients: Care Coordination Institute and American Medical Association Hypertension Control Project Pilot Study results. J Clin Hypertension. 2018;20(1):79-87.

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65. Heo M, Meissner P, Litwin AH, McKee MD, Karasz A, Chambers EC, Yeh MC, Wylie-Rosett J. Reply to Walter et al.’s letter to the editor. Stat Methods Med Res. 2018:962280218767707. PMID: 29633630.

66. Hinen HB, Gathings RM, Shuler MJ, Wine Lee L. Successful treatment of facial milia in an infant with orofaciodigital syndrome type 1.

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67. Litwin AH, Drolet M, Nwankwo C, Torrens M, Kastelic A. Perceived barriers related to the management of HCV infection among physicians prescribing opioid agonist therapy: the C-SCOPE study. Small. 2017;27:13.

68. Lodise TP, Schrank JH. The emperor’s new clothes: prospective observational evaluation of the association between the day 2 vancomycin exposure and failure rates among hospitalized patients with MRSA bloodstream infections (PROVIDE). Open Forum Infect Dis. 2017;4(suppl 1):S30-1.

69. McDermott DF, Joseph RW, Ho T, Vaishampayan U, Ali S, Matrana M, Alter R, Edenfield J, Blanchette S, Gan L, Atkins MB. 896PA Phase (Ph) 1 dose finding study of X4P-001 (an oral CXCR4 inhibitor) and axitinib in patients with advanced renal cell carcinoma (RCC).

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70. Millard M, Lotstein A, Holmes L, Schammel DP, Chung K, Edenfield J, Crosswell HE, DesRochers T. Abstract 1923: Paired isolation and expansion of CSC and CTC from primary small cell lung cancer patient tissue and blood using the 3DKUBE bioreactor platform. Cancer Res. 2017;77(suppl 13):1923.

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72. Naughton MJ, Case LD, Peiffer A, Chan M, Stieber V, Moore D, Falchuk S, Piephoff J, Edenfield WJ, Giguere J, Loghin M, Shaw EG, Rapp SR. Quality of life of irradiated brain tumor survivors treated with donepezil or placebo: results of the WFU CCOP research base protocol 91105. Neuro-Oncol Pract.

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73. Norton BL, Akiyama MJ, Zamor PJ, Litwin AH. Treatment of chronic hepatitis C in patients receiving opioid agonist therapy: a review of best practice. Infect Dis Clin North Am. 2018;32(2):347-70.

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76. Rajan A, Gulley JL, Spigel DR, Iannotti N, Chandler JC, Wong DJL, Leach JW, Edenfield WJ, Wang D, Redfern CH, Grote HJ, von Heydebreck A, Ruisi MM, Munshi N, Kelly K. Avelumab (anti–PD-L1) in patients with platinum-treated advanced NSCLC: 2.5-year follow-up from the JAVELIN Solid Tumor trial. J Clin Oncol. 2018;36(suppl 15):9090.

77. Revilla F, Urrea-Mendoza E. Perceived activities and participation outcomes of a Yoga Intervention for individuals with Parkinson’s disease: a mixed methods study. Int J Yoga Ther. 2018;28(1):51-61.

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80. Sarasua SM, Li J, Hernandez GT, Ferdinand KC, Tobin JN, Fiscella KA, Jones D, Sinopoli A, Egan BM. Opportunities for improving cardiovascular health outcomes in adults younger than 65 years with guideline-recom-

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81. Shuter J, Litwin AH, Sulkowski MS, Feinstein A, Bursky-Tammam A, Maslak S, Weinberger AH, Esan H, Segal KS, Norton B. Cigarette smoking behaviors and beliefs in persons living with hepatitis C. Nicotine Tobacco Res. 2017;19(7):836-44.

82. Sivakumar S. Cerebral pathophysiology in extracorporeal membrane oxygenation: pitfalls in daily clinical management. Crit Care Res Pract. 2018; PMID: 29744226.

83. Sivakumar S. Mystery case: central nervous system post transplant lymphoproliferative disorder. Neurology. 2017;89(4):e32-7.

84. Teixeira PA, Bresnahan MP, Laraque F, Litwin AH, Shukla SJ, Schwartz JM, Reynoso S, Perumalswami PV, Weiss JM, Wyatt B, et al.

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85. Von Hoff DD, Rasco DW, Heath EI, Munster PN, Schellens JHM, Isambert N, Le Tourneau C, O’Neil BH, Mathijssen RH, Lopez-Martin JA, Edenfield WJ, Martín M, LoRusso PM, Bray GL, DiMartino J, Nguyen A, Liu K, Laille E, Bendell JC. Phase I study of CC-486 alone and in combination with carboplatin or nab‑paclitaxel in patients with relapsed or refractory solid tumors. Clin Cancer Res. 2018;24(17):4072-80.

86. Zafar K, Patil N. Inpatient-onset versus outpatient-onset acute coronary syndrome: comparison of clinical features and outcomes.

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OB/GYN 88. Almquist LD, Likes CE, Stone B, Brown KR, Savaris R, Forstein DA, Miller PB, Lessey B. Endometrial BCL6 testing for the prediction of in vitro fertilization outcomes: a cohort study. Fertil Steril. 2017;108(6):1063-9. PMID: 29126613.

89. Bonds CL, Roudebush WE, Lessey B. Sperm motility index and intrauterine insemination pregnancy outcomes. GHS Proc.

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91. Colón-Caraballo M, Torres-Reverón A, Soto-Vargas JL, Young S, Lessey B, Mendoza A, Urrutia R, Flores I. Effects of histone methyltransferase inhibition in endometriosis. Biol Reprod. 2018;99(2):293-307. PMID: 29408993.

92. Eichelberger K. The association between assisted reproduction technology (ART) and abnormal placentation. BJOG. 2018 Jun 13.

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93. Eichelberger K, Alson JG, Doll KM. Should race be used as a variable in research on preterm birth? AMA J Ethics. 2018;20(1):296302. PMID: 29542440.

94. Eichelberger K. Equal pay for equal work in academic obstetrics and gynecology. Obstet Gynecol. 2018;131(2):224-6.

95. Hill A, Lessey B, Flores VA, Taylor HS. Bazedoxifene/conjugated estrogens in combination with leuprolide for the treatment of endometriosis. Clin Case Rep. 2018;6(6):990-4.

96. Keenan-Devlin LS, Ernst LM, Ross KM, Qadir S, Grobman WA, Holl JL, Crockett A, Miller GE, Borders AEB. Maternal income during pregnancy is associated with chronic placental inflammation at birth. Am J Perinatol.

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97. Matson BC, Quinn KE, Lessey B, Young SL, Caron KM. Elevated levels of adrenomedullin in eutopic endometrium and plasma from women with endometriosis. Fertil Steril.

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98. Miller GE, Borders AE, Crockett A, Ross KM, Qadir S, Keenan-Devlin L, Leigh AK, Ham P, Ma J, Arevalo JMG, Ernst LM, Cole SW. Maternal socioeconomic disadvantage is associated with transcriptional indications of greater immune activation and slower tissue maturation in placental biopsies and newborn cord blood. Brain Behav Immun. 2017;64:276-84.

99. Miller J, Ahn S, Monsanto S, Khalaj K, Fazleabas A, Young S, Lessey B, Koti M, Tayade C. Interleukin-33 modulates inflammation in endometriosis. Sci Rep. 2017;7(1):17903. PMID: 28434870.

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101. Strug M, Su R, Kim T, Mauriello A, Young S, Lessey B, Ticconi C, Lim J, Jeong J, Fazleabas A. RBPJ mediates uterine repair in the mouse and is reduced in women with recurrent pregnancy loss. FASEB J. 2018;32(5):2452-66.

102. Surrey E, Taylor HS, Giudice L, Lessey B, Abrao MS, Archer DF, Diamond MP, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Singh SS, Rechberger T, Agarwal SK, Duan WR, Schwefel B, Thomas JW, Peloso PM, Ng J, Soliman AM, Chwalisz K. Long-term outcomes of elagolix in women with endometriosis: results from two extension studies. Obstet Gynecol.

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103. Taylor HS, Giudice LC, Lessey B, Abrao MS, Kotarski J, Archer DF, Diamond MP, Surrey E, Johnson NP, Watts NB, Gallagher C, Simon JA, Carr B, Dmowksi WP, Leyland N, Rowan JP, Duan WR, Ng J, Schwefel B, Thomas JW, Jain RI, Chwalisz K. Treatment of endometriosis-associated pain with elagolix, an oral GnRH antagonist. N Engl J Med. 2017;377:2840. PMID: 28525302.

104. Young SL, Savaris RF, Lessey B, Sharkey AM, Balthazar U, Zaino RJ, Sherwin RA, Fritz MA. Effect of randomized serum progesterone concentration on secretory endometrial histologic development and gene expression.

Hum Reprod. 2017;32(9):1903-14. PMID: 28854727.

105. Zhang T, Zhou J, Man G, Liang B, Leung K, Xiao B, Ma X, Huang H, Huang S, Hegde V, Zhong Y, Li Y, Yiu A, Kong G, Kwong J, Ng P, Lessey B, Nagarkatti M, Nagarkatti P, Wang C. MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target. Eur J Immunol.

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Orthopaedics 106. Abildgaard JT, Lonergan KT, Tolan SJ, Kissenberth MJ, Hawkins RJ, Washburn R, Adams KJ, Long C, Shealy EC, Motley JR, Tokish J. Liposomal bupivacaine versus indwelling interscalene nerve block for postoperative pain control in shoulder arthroplasty: a prospective randomized controlled trial. J Shoulder Elbow Surg. 2017;26(7):1175-81.

107. Asif I, Annett S, Ewing J, Abdelfattah R. Psychological impact of electrocardiogram screening in NCAA athletes. Brit J Sports Med. 2017;51(20):1489-92.

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2018 PUBLICATIONS 108. Burnikel BG. Amniotic messenchymal stem cells mitigate osteoarthritis progression in a synovial macrophage-medicated in vitro explant coculture model. J Tissue Eng Regenerative Med. 2018;12(4):1097-110.

109. Carpenter JE, Bagian JP, Snider RG, Jeray K. Medical team training improves team performance: AOA critical issues. J Bone Joint Surg.

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110. Denninger TR, Cook CE, Chapman CG, McHenry TP, Thigpen CA. The influence of patient choice of first provider on costs and outcomes: analysis from a physical therapy patient registry. J Orthop Sports Phys Ther.

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111. Finkemeier C, Adams J, Bernstein M, Lee MA, Harvey E, Crist BD. Biomechanics – hot topics part II. J Orthop Trauma. 2018;32(suppl)(1):S29-32.

112. Gruber HE, Ashraf N, Cox MD, Ingram JA, Templin M, Wattenbarger JM. Experimental induction of physeal injuries by fracture, drill, and ablation techniques: analyses of immunohistochemical findings. J Pediatr Orthop. 2017 Nov 16. PMID: 29189533.

113. Hedrick B, Gettys FK, Richards S, Muchow RD, Jo CH, Abbott MD. Percutaneous heel cord release for clubfoot: a retrospective, multicentre cost analysis. J Child Orthop. 2018;12(3):273-8.

114. Hendrix ST, Kwapisz A, Wyland DJ. All-inside arthroscopic meniscal repair technique using a midbody accessory portal. Arthrosc Tech.

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115. Jackson LT, Crisler MC, Tanner S, Brooks JO, Jeray K. Effects of upper extremity immobilization and use of a spinner knob on vehicle steering. Hand. 2017;12(6):597-605.

116. Lazarus D, Farnsworth CL, Jeffords ME, Marino N, Hallare J, Edmonds EW. Torsional growth modulation of long bones by oblique plating in a rabbit model. J Ped Orthop. 20181;38(2):e97-103.

117. Luedke C, Kissenberth MJ, Tolan SJ, Hawkins RJ, Tokish J. Outcomes of anatomic total shoulder arthroplasty with B2 glenoids. JBJS Reviews.

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118. Madden K, Scott T, McKay P, Petrisor BA, Jeray K, Tanner S, Bhandari M, Sprague S. Predicting and preventing loss to follow-up of adult trauma patients in randomized controlled trials: an example from the FLOW trial. J Bone Joint Surg.

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119. McConomy S, Brooks J, Venhovens P, Xi Y, Rosopa P, DesJardins J, Kopera K, Drouin N, Belle L, Truesdail C, Tanner S, Hennessy S, Lococo K,

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Staplin L, Schold Davis E. Evaluation of CarFit criteria compliance and knowledge of seat adjustment. SAE Technical Paper. 2018 Apr 3.

120. Momaya AM, Beicker C, Siffri PC, Kissenberth MJ, Backes J, Bailey L, Rulewicz GJ, Mercuri JM, Shealy EC, Tokish J, Thigpen CA. Preoperative ultrasonography is unreliable in predicting hamstring tendon graft diameter for ACL reconstruction. Orthop J Sports Med. 2018;6(1):2325967117746146.

121. Momaya AM, Kwapisz A, Choate WS, Kissenberth MJ, Tolan SJ, Lonergan KT, Hawkins RJ, Tokish J. Clinical outcomes of suprascapular nerve decompression: a systematic review. J Shoulder Elbow Surg. 2018;27(1):172-80.

122. Porter SE, Razi AE, Ramsey TB. Novel strategies to improve resident selection by improving cultural fit: AOA critical issues. J Bone Joint Surg.

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123. Roberson TA, Bentley JC, Griscom JT, Kissenberth MJ, Tolan SJ, Hawkins RJ, Tokish J. Outcomes of total shoulder arthroplasty in patients younger than 65 years: a systematic review. J Shoulder Elbow Surg. 2017;26(7):1298-1306.

124. Roberson TA, Abildgaard JT, Wyland DJ, Siffri PC, Geary SP, Hawkins RJ, Tokish JT. “Proprietary processed” allografts: clinical outcomes and biomechanical properties in anterior cruciate ligament reconstruction. Am J Sports Med. 2017;45(13):3158-67.

125. Seiler JG, Daruwalla JH, Payne SH, Faucher G. Normal palmar anatomy and variations that impact median nerve decompression. J Am Acad Orthop Surg. 2017;25(9):e194-203.

126. Sprague S, Petrisor BA, Jeray K, McKay P, Scott T, Heels-Ansdell D, Schemitsch EH, Liew S, Guyatt GH, Walter SD, Bhandari M. Factors associated with health-related quality of life in patients with open fractures. J Orthop Trauma.

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127. Sprague S, Petrisor B, Jeray K, McKay P, Heels-Ansdell D, Schemitsch E, Liew S, Guyatt G, Walter SD, Bhandari M. Wound irrigation does not affect health-related quality of life after open fractures: results of a randomized controlled trial. Bone Joint J. 2018;100-B(1):88-94.

128. Stasikelis PJ, Carpenter AM. Results of casting in severe curves in infantile scoliosis. J Pediatr Orthoped. 2018;38(4):e186-9.

129. Torres EG, Anderson AB, Broome B, Geary SP, Burnikel BG. Liposomal membrane bound bupivacaine versus femoral nerve catheter in TKA. Am J Orthoped. 2017;46(6):e414-8.

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130. Watson ST, Allen B, Robbins C, Bedi A, Gagnier JJ, Miller B. Does the rotator cuff tear pattern influence clinical outcomes after surgical repair? Orthop J Sports Med. 2018;6(3):2325967118763107.

131. Watson ST, Gudger GK, Long C, Tokish J, Tolan SJ. Outcomes of trabecular metal-backed glenoid components in anatomic total shoulder arthroplasty. J Shoulder Elbow Surg.

2018;27(3):493-8.

142. Slizewski DH, Heberlein E, Meredith J, Jobe LB, Eichelberger K. Impact of home versus hospital dressing on bacterial contamination of surgical scrubs in the obstetric setting: a randomized controlled trial. Am J Infect Control.

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132. Watson ST, Robbins CB, Bedi A, Carpenter JE, Gagnier JJ, Miller BS. Comparison of outcomes 1Â year after rotator cuff repair with and without concomitant biceps surgery. Arthroscopy. 2017;33(11):1928-36.

143. Snyder B, Beets JW, Lessey B, Horton SRW, Abrams G. Postmenopausal deep infiltrating endometriosis of the colon: rare location and novel medical therapy. Case Rep Gastrointest Med. 2018;2018:9587536.

133. Westberry DE, Wack LI, Davis RB, Hardin JW. Femoral anteversion assessment: comparison of physical examination, gait analysis, and EOS biplanar radiography. Gait Posture.

2018;62:285-90.

144. Wapshott T, Schammel C, Schammel DP, Rezeanu L, Lynn M. Primary undifferentiated sarcoma of the meninges: a case report and comprehensive review of the literature. J Clin Neurosci. 2018;54:128-35.

134. Westberry DE, Carpenter AM, Barrera J, Westberry A. Management of tibial bow in fibular deficiency. J Pediatr Orthop. 2018 Apr 20. PMID: 29683857.

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135. Westberry, DE. State of the art: amputation and prosthetics. J Pediatr Orthop. 2017;37(suppl)(2):S22-5.

136. Westberry DE, Carpenter AM. 3D modeling of lower extremities with biplanar radiographs: reliability of measures on subsequent examinations. J Pediatr Orthop. 2017 Aug 2. PMID: 28777285.

137. Xi Y, Brooks J, Venhovens P, Rosopa P, DesJardins J, McConomy S, Belle L, Drouin N, Hennessy S, Kopera K, McKee J, Tanner S, Truesdail C, Lococo K, Staplin L. Understanding the automotive pedal usage and foot movement characteristics of older drivers. SAE Technical Paper. 2018 Apr 3.

Pathology 138. Abrams G, Chapman R, Horton SRW. Refractory hepatic hydrothorax: a rare complication of systemic sclerosis and presinusoidal portal hypertension. Case Rep Hepatol.

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139. Gudakova I, Kim JP, Meredith J, Webb G. Microbial contamination on touch surfaces in sick- and well-child waiting rooms in pediatric outpatient facilities. Pediatr Infect Dis J. 2017;36(12):e303-6.

140. Hutchinson JC, Fulcher JW, Hanna J, Ward M. Pulmonary tumor thrombotic microangiopathy: case report and review of literature. Am J Forensic Med Pathol. 2018;39(1):56-60.

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141. Monico J, Miller B, Rezeanu L, May W, Sullivan DC. Fibroblast growth factor receptor 1 amplification in laryngeal squamous cell carcinoma. PloS One. 2018;13(1):e0186185.

145. Bixler GM, Powers GC, Clark RH, Walker MWW, Tolia VN. Changes in the diagnosis and management of patent ductus arteriosus from 2006 to 2015 in United States neonatal intensive care units. J Pediatr. 2017;189:10512. PMID: 28600155.

146. Blomquist KK, Griffin SF, Schmalz DL, Sease KK, Reeves CB. Behavioral and psychological predictors of BMI reduction in children seeking treatment at a hospital clinicâ&#x20AC;&#x2122;s family-based pediatric weight management program. J Child Obes. 2018;3(2):10-7.

147. Bruch JS, Stancil MD, Odom JM, Nelson BA. Employee health: diabetes self-management with wireless meter. Diabetes. 2018;67(suppl 1):651P. 148. Buchanan AO. Pediatric nutrition and nutritional disorders (5 chapters). In: Marcdante K, Kliegman R, eds. Nelson Essentials of Pediatrics. 8th ed. Philadelphia, PA: Elsevier; 2018.

149. Buchanan AO. Gastrointestinal bleeding. In: Zaoutis L, Chiang V, eds. Comprehensive Pediatric Hospital Medicine. 2nd ed. New York, NY: McGraw-Hill Education; 2018.

150. Casanova M. Effects of 12 and 18 sessions of rTMS on autonomic activity in autism spectrum disorder. Appl Psychophysiol Biofeedback. 2017;42(2):155.

151. Chung E, Gable K, Golden C, Hudson JA, Hackman N, Andrews J, Jackson DA, Beavers J, Mirchandani D, Kellams A, Krevitsky M, Monroe K, Madlon-Kaye D, Stratbucker W, Campbell D, Collins J, Rauch D. Current scope GHS Proc. December 2018; 3 (1): 31-46

2018 PUBLICATIONS of practice for newborn care in non-intensive hospital settings. Hosp Pediatr. 2017;7(8):47182. PMID: 28694290.

152. Crowder J, Asif I, Reeves CB, Blomquist K, Brackbill E, Utecht L, Griffin S, Schmalz D, Sease KK, Nelson V. Exercise programming correlates with patient success in a comprehensive pediatric weight loss program. Clin J Sport Med. 2018;28(2):239-48.

153. Gade AR, Patel M, West DR, Abrams G. Prevalence of HCV infection in adults with congenital heart disease and treatment with direct antiviral agents. South Med J. 2018;111(3):13741. PMID: 29505646.

154. Grisham M. Iron deficiency anemia. Focus Pediatr. 2018;30(1):18-9.

155. Hasan SU, Potenziano J, Konduri GG, Perez JA, Van Meurs KP, Walker MWW, Yoder BA. Effect of inhaled nitric oxide on survival without bronchopulmonary dysplasia in preterm infants: a randomized clinical trial. JAMA Pediatr. 2017;171(11):1081-9. PMID: 28973344.

156. Helsel BC, Williams JE, Lawson K, Liang J, Markowitz JE. Telemedicine and mobile health technology are effective in the management of digestive diseases: a systematic review. Dig Dis Sci. 2018;63(6):1392-408.

157. Hintze JP, Edinger JD. Hypnotic discontinuation in chronic insomnia. Sleep Med Clin.

2018;13(2):263-70.

158. Huang KZ, Jensen ET, Chen HX, Landes LE, McConnell KA, Almond MA, Johnston DT, Durban R, Jobe L, Frost C, Donnelly S, Antonio B, Safta AM, Quiros JA, Markowitz JE, Dellon ES. Practice pattern variation in pediatric eosinophilic esophagitis in the Carolinas EoE Collaborative: a research model in community and academic practices. South Med J. 2018;111(6):328-32. PMID: 29863219.

159. Jasser S, Foster N, Nelson BA, Kittelsrud J, DiMeglio L, Quinn M, Willi S, Simmons J. Sleep in children with type 1 diabetes and their parents in T1D exchange. Sleep Med. 2017;39:108-15.

160. Johnson S, Trejo G, Beck KL, Worsley C, Tranberg H, Plax KL, Linton JM. Building community support using a modified World Café method for pregnant and parenting teenagers in Forsyth County, North Carolina.

J Pediatr Adolesc Gynecol. 2018;31(6):614-9.

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161. Jordan M, Stoichita A, Hudson JA. Choosing high-value care in the evaluation and treatment of newborns at risk for early-onset sepsis. GHS Proc. 2017;2(2):94-5.

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162. Kelly DP. Sensory impairments: hearing and vision. In: Macias M, ed. Developmental and Behavioral Pediatrics. 2nd ed. American Academy of Pediatrics; 2018.

163. Kelly DP, Sokhadze EM, Casanova E, Khachidz I, Wang Y, Li X. Application of ERPs in autism research and as functional outcomes of neuromodulation treatment. Int J Med Bio Frontiers. 2017;23(2):168-211.

164. Khosla S, Deak MC, Gault D, Goldstein CA, Hwang D, Kwon Y, O’Hearn D, Schutte-Rodin S, Yurcheshen M, Rosen IM, Kirsch DB, Chervin RD, Carden KA, Ramar K, Aurora RN, Kristo DA, Malhotra RK, Martin JL, Olson EJ, Rosen CL, Rowley JA. Consumer sleep technology: an American Academy of Sleep Medicine position statement. J Clin Sleep Med. 2018;14(5):877-80. PMID: 29734997.

165. Linton JM, Stockton MP, Andrade B, Daniel S. Integrating parenting support within and beyond the pediatric medical home. Global Pediatr Health. 2018;5:2333794X18769819.

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166. Linton JM, Reichard E, Peters A, Albertini LW, Miller-Fitzwater A, Poehling K. Enhancing resident education and optimizing care for children with special health care needs in resident continuity clinics. Academic Pediatr.

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167. Linton JM. The child witness in the courtroom. Pediatrics. 2017;139(3).

168. Linton JM. The Community Pediatrics Training Initiative project planning tool: a practical approach to community-based advocacy.

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169. Makhija P, Wilson C, Garimella S. Utility of Doppler sonography for renal artery stenosis screening in obese children with hypertension.

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170. Mann-Jackson L, Song EY, Tanner AE, Alonzo J, Linton JM, Rhodes SD. The health impact of experiences of discrimination, violence, and immigration enforcement among Latino men in a new settlement state. Am J Men’s Health. 2018 Jun 1:1557988318785091. PMID: 29962271.

171. Markowitz JE. Attitudes and beliefs about the use of mobile technology to improve the self-management and patient-provider communication among a sample of pediatric patients with eosinophilic esophagitis. J SC Med Assoc.

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172. Markowitz JE. Safety and efficacy of reslizumab for children and adolescents with eosino39

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173. Markowitz JE. Pediatric Inflammatory Bowel Disease. 3rd ed. New York, NY: Springer; 2017.

174. Markowitz JE, Clayton SB. Eosinophilic esophagitis in children and adults. Gastrointest Endosc Clin North Am. 2018;28(1):59-75.

175. Merritt M, Kline H, Seigler RS, Garimella S. Pseudohyperkalemia in a patient with T-cell acute lymphoblastic leukemia and hyperleukocytosis. J Pediatr Intensive Care. 2018;DOI 10.1055/s-0038-1624569.

176. Michael L, Brady AK, Russell G, Rhodes SD, Namak S, Cody L, Vasquez A, Caldwell A, Foy J, Linton JM. Connecting refugees to medical homes through multi-sector collaboration.

J Immigrant Minority Health. 2018 May 16.

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177. Nelson BA, Williams J, Helsel B, Eke R. Exercise considerations for type 1 and type 2 diabetes. ACSMâ&#x20AC;&#x2122;s Health and Fitness J. 2018;22(1):10-6.

178. Nunley SR, Glynn P, Rust S, Vidaurre J, Albert DVF, Patel AD. Healthcare utilization characteristics for intranasal midazolam versus rectal diazepam. J Child Neurol.

2018;33(2):158-63. PMID: 29233042.

179. Saul RA, Garner AS. Thinking Developmentally: Nurturing Wellness in Childhood to Promote Lifelong Health. Itasca, IL: American Academy of Pediatrics; 2018.

180. Singh A, Klick JC, McCracken CE, Hebbar KB. Evaluating hospice and palliative medicine education in pediatric training programs.

Am J Hospice Palliative Care. 2017;34(7):60310. PMID: 27122617.

181. Sokhadze G, Casanova MF, Kelly DP, Sokhadze EM. Effects of 12 and 18 sessions of rTMS on autonomic activity in autism spectrum disorder. Appl Psychophysiol Biofeedback.

2017;42(2):155.

182. Summey J, Chen L, Mayo R, Charron E, Hudson JA, Sherrill W, Dickes L. Early treatment for opioid-dependent newborns in South Carolina improves health outcomes: a retrospective comparison with traditional care, 2006-2014.

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183. Tamborlane WV, Cheng P, Gal RL, Kollman C, Van Name MA, Lynch JL, Nelson BA. T1D and T2D youth in the Pediatric Diabetes Consortium (PDC) Registries: comparing clinical characteristics and glycemic control. Diabetes.

2018;67(suppl 1):1340-P. 40

184. Uwemedimo OT, Monterrey AC, Linton JM. A dream deferred: ending DACA threatens children, families, and communities. Pediatr.

2017;140(6). PMID: 28993446.

185. Wood J, Boyle C, Quinn M, Wong JC, Haller MJ, Nelson BA, Schatz D. Impact of target HbA1c change in pediatric participants in the T1D exchange clinic registry. Diabetes.

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Psychiatry 186. Griffeth B. The successful integration of psychiatry and neurology in a combined clerkship.

Acad Psychiatry. 2017;41(4):547-50.

187. Holder S, Warren C., Rogers K, Griffeth B, Peterson E, Blackhurst DW, Ochonma C. Involuntary processes: knowledge base of health care professionals in a tertiary medical center in upstate South Carolina. Community Ment Health J. 2018;54(2):149-57.

188. Holder S, Rogers K, Peterson E, Ochonma C. Mental health visits: examining socio-demographic and diagnosis trends in the emergency department by the pediatric population. Child Psychiatry Hum Dev. 2017;48(6):993-1000.

189. Saul JR, Holder S, Lokey JS. Employing the patient-centered collaborative care approach: a case study of a complex geriatric patient with psychopathology of treatment resistant depression and primary hyperparathyroidism. J Ment Health Aging. 2018;2(1):18-23.

Radiology 190. Brechtel L, Womack L, Ubah C, Gainey J, Jain S, Gainey J, Pendergrass J, Faulkner R, Ingiaimo M, Black A, Madeline LA, Troup C, Nathaniel T. Early clinical experience in a year one medical neuroscience course enhances studentsâ&#x20AC;&#x2122; performance. Med Sci Educator.

2018;28(2):315-26.

191. Colello MJ, Ivey LE, Gainey J, Faulkner RV, Johnson A, Brechtel L, Madeline LA, Nathaniel T. Pharmacological thrombolysis for acute ischemic stroke treatment: gender differences in clinical risk factors. Adv Med Sci. 2018;63(1):100-6.

192. Devane AM, Freeman B, Powell B, Hale A, Gandhi S. Traumatic aorto-cisterna chyli fistula with treatment of aortic pseudoaneurysm with CT-guided thrombin injection.

Ann Vascular Surg. 2018; DOI: 10.1016/j. avsg.2018.02.053.

193. Devane A, Absher J, Madeline L, Rayes S, Webb S. Cerebrovascular disease. In reference module in Neuroscience and Biobehavioral Psychology: Elsevier; 2018.

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2018 PUBLICATIONS 194. Gainey J, Brechtel L, Konklin S, Madeline LA, Lowther E, Blum B, Nathaniel T. In a stroke cohort with incident hypertension; are more women than men likely to be excluded from recombinant tissue-type Plasminogen Activator (rtPA)? J Neurol Sci. 2018;387:139-46.

195. Gimbel RW, Pirrallo RG, Lowe SC, Wright DW, Zhang L, Woo MJ, Fontelo P, Liu F, Connor Z. Effect of clinical decision rules, patient cost and malpractice information on clinician brain CT image ordering: a randomized controlled trial. BMC Med Inform Decis Mak. 2018;18(1):20.

196. Nathaniel T, Gainey J, Blum B, Montgomery C, Ervin L, Madeline LA. Clinical risk factors in thrombolysis therapy: telestroke versus nontelestroke. J Stroke Cerebrovascular Dis. 2018;27(9):2524-33.

Surgery 197. Beathard GA, Lok CE, Glickman MH, Al-Jaishi AA, Bednarski D, Cull D, Lawson JH, Lee TC, Niyyar VD, Syracuse D, Trerotola SO, Roy-Chaudhury P, Shenoy S, Underwood M, Wasse H, Woo K, Yuo TH, Huber TS. Definitions and end points for interventional studies for arteriovenous dialysis access. Clin J Am Soc Nephrol. 2018;13(3):501-12. PMID: 28729383.

198. Beffa LR, Carbonell A. Component separation: robotic approach. In: LeBlanc KA, Kingsnorth A, Sanders DL, eds. Management of Abdominal Hernias. 5th ed. New York, NY: Springer; 2018:423-30.

199. Beffa LR, Margiotta AL, Carbonell A. Flank and lumbar hernia repair. Surg Clinics North Am. 2018;98(3):593-605. PMID: 29754624.

200. Beffa LR, Warren J, Cobb W, Knoedler B, Ewing JA, Carbonell A. Open retromuscular repair of parastomal hernias with synthetic mesh. Am Surg. 2017;83(8):906-10. PMID: 28822400.

201. Begley HR, Gray B. Images in vascular medicine: the case of the blue-gray fingernails. Vasc Med. 2018;23(3):291-2. PMID: 28697693.

202. Bismuth J, Gray B, Holden A, Metzger C, Panneton J. Pivotal study of a next-generation balloon-expandable stent-graft for treatment of iliac occlusive disease. J Endovascular Ther.

2017;24(5):629-37. PMID: 28697693.

203. Bolton W, Cochran T, Ben-Or S, Stephenson J, Ellis W, Hale A, Binks A. Electromagnetic navigational bronchoscopy reduces the time required for localization and resection of lung nodules.

Innovations. 2017;12(5):333-7. PMID: 28777130.

204. Bonett A, Shirley SH, Culpepper W. Lower GHS Proc. December 2018; 3 (1): 31-46

extremity reconstruction: revisiting the crossleg flap. GHS Proc. 2017;2(2):148-51.

205. Bunte MC, Cohen DJ, Jaff MR, Gray WA, Magnuson EA, Li H, Feiring A, Cioppi M, Hibbard R, Gray B, Khatib Y, Jessup D, Patarca R, Du J, Stoll HP, Massaro J, Safley DM. Long-term clinical and quality of life outcomes after stenting of femoropopliteal artery stenosis: 3-year results from the STROLL study.

Cathet Cardiovasc Interventions. 2018; DOI: 10.1002/ccd.27569. PMID: 29521013.

206. Carbonell A, Warren J, Prabhu AS, Ballecer CD, Janczyk RJ, Herrera J, Huang LC, Phillips S, Rosen MJ, Poulose BK. Reducing length of stay using a robotic-assisted approach for retromuscular ventral hernia repair: a comparative analysis from the Americas Hernia Society Quality Collaborative. Ann Surg.

2018;267(2):210-7. PMID: 28350568.

207. Carbonell A. Endorsement of the HerniaSurge guidelines by the Americas Hernia Society.

Hernia. 2018;22(1):171. PMID: 29330829.

208. Cull JD, Fleetwood VA, Manning B, Chan EY. Healthcare workersâ&#x20AC;&#x2122; attitude toward organ donation at two level 1 urban trauma. Am Surg.

2017;83(9):389-91. PMID: 28958262.

209. Davis JR, Hale A, Ewing JA, Lokey J. Instituting ultrasound-guided FNA for thyroid nodules into a general surgery residency program: what we learned. J Surg Education. 2018;75(3):594600. PMID: 29175058.

210. Erwin PA, Beffa LR, Jones W, Hale A, Scott J. Metallic surgical clip causing cholangitis after cholecystectomy. Am Surg. 2017;83(9):403-5.

PMID: 28958267.

211. Fanous M, Warren J, Cobb W. Superiority of Roederâ&#x20AC;&#x2122;s knot for fascial mesh fixation in a cadaveric model. Surg Innovation.

2017;24(4):365-8. PMID: 28689486.

212. Fatula LK, Bolton W, Hale A, Davis B, Stephenson J, Ben-Or S. Atrial esophageal fistula secondary to ablation for atrial fibrillation: a case series and review of the literature. Innovations. 2017;12(4):e3-5. PMID: 28753141.

213. Fox SS, Janczyk R, Warren J, Carbonell A, Poulose BK, Rosen MJ, Hope WW. An evaluation of parastomal hernia repair using the Americas Hernia Society Quality Collaborative. Am Surgeon. 2017;83(8):881-6. PMID: 28822396.

214. Freeman BM, Powell BC, Devane AM, Hale A, Gandhi S. Traumatic aorto-cisterna chlyi fistula with treatment of aortic pseudoaneurysm with CT-guided thrombin injection. Annals Vasc Surg. 2018; May 18. PMID: 29778611.

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215. Frykberg RG, Gordon IL, Reyzelman AM, Cazzell SM, Fitzgerald R, Rothenberg GM, Bloom JD, Petersen BJ, Linders DR, Nouvong A, Najafi B. Feasibility and efficacy of a smart mat technology to predict development of diabetic plantar ulcers. Diabetes Care.

2017;40(7):973-80. PMID: 28465454.

216. Gandhi S, Carsten C. Complex hemodialysis access. In: Rutherford’s Vascular Surgery. 9th ed. London: Elsevier; June 15, 2018.

217. Gandhi S, Cull D. Upper extremity revascularization procedures. Online under Vascular Territories in Vasc & Endovasc Surg. 2018.

218. Gandhi S, Ewing JA, Cooper E, Chaves JM, Gray B. Comparison of low-dose catheter-directed thrombolysis with and without pharmacomechanical thrombectomy for acute lower extremity ischemia. Annals Vasc Surgery.

2018;46:178-86. PMID: 28739471.

219. Gil D, Rex J, Cobb W, Reukov V, Vertegel A. Anti-inflammatory coatings of hernia repair meshes: a pilot study. J Biomed Materials Res. 2018;106(2):589-97. PMID: 28263435.

220. Goff T, Cull JD. Improved intraoperative communication after utilization of navigational grids during laparoscopic cholecystectomies.

Am Surg. 2018;84(5):727-31. PMID: 29966575.

221. Gray B. Updates from the ABVM and SVM. Vascular Med. 2018;23(1):91-2.

222. Hancock BH, Warren J, Marguet C, Carbonell A, Cobb W. Concurrent laparoscopic hernia repair and cystoscopic laser cystolitholaxapy for urinary bladder calculus contained within a direct inguinal hernia. Am Surgeon.

2017;83(9):406-8. PMID: 28958268.

223. Hawkins AT, Ford MM, Benjamin Hopkins M, Muldoon RL, Wanderer JP, Parikh AA, Geiger, TM. Barriers to laparoscopic colon resection for cancer: a national analysis. Surg Endosc.

2018;32(2):1035-42. PMID: 28840352.

224. Hernandez MC, Haddad NN, Cullinane DC, Yeh DD, Wydo S, Inaba K, Duane TM, Pakula A, Skinner R, Rodriguez CJ, Dunn J, Sams VG, Zielinski MD, Choudhry A, Turay D, Yune JM, Watras J, Widom KA, Cull JD, Toschlog EA, Graybill JC. The American Association for the Surgery of Trauma severity grade is valid and generalizable in adhesive small bowel obstruction. J Trauma Acute Care Surg. 2018;84(2):372-8. PMID: 29117026.

225. Hu Q, Shi L, Chen L, Zhang L, Truong K, Ewing A, Wu J, Scott J. Seasonality in the adverse outcomes in weight loss surgeries. Surg Obes Related Dis. 2018;14(3):291-6.

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226. Hutcheon DA, Hale A, Ewing JA, Miller M, Couto F, Bour E, Cobb WS, Scott J. Short-term preoperative weight loss and postoperative outcomes in bariatric surgery. J Am Coll Surg.

2018;226(4):514-24. PMID: 29402531.

227. Klein AJ, Jaff MR, Gray B, Aronow HD, Bersin RM, Diaz-Sandoval LJ, Dieter RS, Drachman DE, Feldman DN, Gigliotti OS, Gupta K, Parikh SA, Pinto DS, Shishehbor MH, White CJ. SCAI appropriate use criteria for peripheral arterial interventions: an update. Cathet Cardiovasc Interventions. 2017;90(4):e90-110.

PMID: 28489285.

228. Krpata DM, Prabhu AS, Carbonell A, Haskins IN, Phillips S, Poulose BK, Rosen MJ. Drain placement does not increase infectious complications after retromuscular ventral hernia repair with synthetic mesh: an AHSQC analysis.

J Gastrointest Surg. 2017;21(12):2083-9. PMID: 28983795.

229. Lather HD, Gornik HL, Olin JW, Gu X, Heidt ST, Kim ESH, Kadian-Dodov D, Sharma A, Gray B, Jaff MR, Chi YW, Mace P, Kline-Rogers E, Froehlich JB. Prevalence of intracranial aneurysm in women with fibromuscular dysplasia: a report from the US Registry for Fibromuscular Dysplasia. JAMA Neurol.

2017;74(9):1081-7. PMID: 28715558.

230. Leahey A, Bethel S, Summey J, Heavner S. Patient’s perceptions of clinical scribe use in outpatient physician practices. GHS Proc.

2(2):131-6.

231. Lillemoe KD, Klingensmith ME, Darzi A, Taylor S. American Surgical Association presidential forum: a lifetime of surgical education: can we do better? Ann Surg. 2017;266(4):555-63.

PMID: 28902003.

232. Logghe HJ, McFadden C, Tully NJ, Jones C. History of social media in surgery. Clin Colon Rectal Surg. 30(4):233-9.

233. Low M, Ben-Or S. Thoracic surgery in early-stage small cell lung cancer. Thorac Surg Clin. 2018;28(1):9-14. PMID: 29150041.

234. Macks C, Gwak SJ, Lynn M, Lee JS. Rolipram-loaded polymeric micelle nanoparticle reduces secondary injury after rat compression spinal cord injury. J Neurotrauma.

2018;35(3):582-92. PMID: 29065765.

235. Morgan KM, Erwin PA, Rochester SN, Williams CF, Gates RL. Pediatric gastric ganglioneuroma presenting as anemia. J Pediatric Surg Case Rep. 2018;31:7-9.

236. Namouz T, Carsten C, Hale AL, Walker EJ, Springhart P. A renal arteriovenous malforGHS Proc. December 2018; 3 (1): 31-46

2018 PUBLICATIONS mation case study: the importance of utilizing color Doppler during point-of-care sonography.

J Diagn Med Sonography. 34(2):128-31.

237. Nealon SW, Hale A, Haynes E, Hagood-Thompson C, Marguet C, Ewing JA, Springhart P. Improving patient outcomes and healthcare provider communication with a small, yellow plastic band: the Patient URinary Catheter Extraction (PURCE) protocol. Urology Pract.

2018;5(1):1-6.

238. Nickloes T, Long C, Mack L, Kallab A, Dunlap A, Gandhi S. Superior vena cava syndrome.

Medscape. 2018; Mar 26.

239. Patel PN, Jayawardena ADL, Walden RL, Penn EB, Francis DO. Evidence-based use of perioperative antibiotics in otolaryngology. Otolaryngol Head Neck Surg. 2018;18(5):783-800. PMID: 29405833.

240. Patel PN, Arambula AM, Wheeler AP, Penn EB. Post-tonsillectomy hemorrhagic outcomes in children with bleeding disorders at a single institution. Int J Pediatr Otorhinolaryngol. 2017 Sep;100:216-22. PMID: 28802375.

241. Pingree CS, Majors JS, Howard NS, Eller RL. Laryngocardiac reflex: a case report and review of the literature. J Voice. 2018;32(5):633-5.

PMID: 29079124.

242. Postlewait LM, Ethun CG, McInnis MR, Merchant N, Parikh AA, Idrees K, Isom CA, Hawkins W, Fields RC, Strand M, Weber SM, Cho CS, Salem A, Martin RCG, Scoggins C, Bentrem D, Kim HJ, Carr J, Ahmad S, Abbott D, Wilson GC, Kooby DA, Maithel SK. The hand-assisted laparoscopic approach to resection of pancreatic mucinous cystic neoplasms: an underused technique? Am Surg. 2018;84(1):56-62. PMID: 29428029.

243. Poulose BK, Harris DA, Phillips S, Janczyk RJ, Yunis J, Voeller GR, Carbonell A, Warren J, Stoikes N, Webb D, Hope WW, Rosen MJ. Reducing early readmissions after ventral hernia repair with the Americas Hernia Society Quality Collaborative. J Am Coll Surg.

2018;226(5):814-24. PMID: 29428233.

244. Powell B, Bolton W. Management of lung cancer with concomitant cardiac disease. Thorac Surg Clin. 2018;28(1):69-79. PMID: 29150039.

245. Schneider AM, Manning B, Bolton W. Rare cause of pneumopericardium in a patient following a motor vehicle collision. Am Surg.

2017;83(8):305-7. PMID: 28822369.

246. Schneider AM, Disbrow DE, Ewing JA, Rex J. Laparoscopic management of appendiceal mucoceles. GHS Proc. 2017;2(2):144-7.

GHS Proc. December 2018; 3 (1): 31-46

247. Schneider A, Hutcheon DA, Hale A, Ewing JA, Miller M, Scott J. Postoperative outcomes in bariatric surgical patients participating in an insurance-mandated preoperative weight management program. Surg Obes Related Dis. 2018;14(5):623-30. PMID: 29525261.

248. Scott J, Morton JM. Advocacy for bariatric and metabolic surgery. Curr Surg Rep. 2018;6:17.

249. Shi L, Scott J, Truong K, Qingwei H, Ewing A, Chen L, Zhang L. Changes in utilization and peri-operative outcomes of bariatric surgery in a large US hospital database, 2011-2014. PLoS One. 2017;12(10):e0186306. PMID: 29053709.

250. Slovut DP, Gray B, Saiar A, Bates MC. Evidence-based medicine and contemporary certification: analysis of the American Board of Vascular Medicine endovascular board examination. Vasc Med. 2017;22(4):337-42. PMID: 28594284.

251. Snyder RA, Hu CY, Cuddy A, Francescatti AB, Schumacher JR, Van Loon K, You YN, Kozower BD, Greenberg CC, Schrag D, Venook A, McKellar D, Winchester DP, Chang GJ. Association between intensity of posttreatment surveillance testing and detection of recurrence in patients with colorectal cancer. JAMA. 2018;319(20): 2104-15. PMID: 29800181.

252. Snyder RA, Prakash LR, Nogueras-Gonzalez GM, Kim MP, Aloia TA, Vauthey JN, Lee JE, Fleming JB, Katz MHG, Tzeng CD. Vein resection during pancreaticoduodenectomy for pancreatic adenocarcinoma: Patency rates and outcomes associated with thrombosis. J Surg Oncol. 2018;117(8):1648-54. PMID: 29723419.

253. Snyder RA, Vauthey JN. Hepatobiliary Cancers. In: Feig BW, Ching CD, Roland C. eds.: Wolters Kluwer; June 23, 2018. The MD Anderson Surgical Oncology Handbook. Wolters Kluwer; June 23, 2018. Chapter 13.

254. Sprunger H, Carbonell A, Marguet C, Cobb W, Warren J, Flanagan W. Staged management of giant inguinoscrotal hernia. Am Surg.

2018;84(3):e114-6. PMID: 29559042.

255. Warren J, Stoddard C, Hunter AL, Horton AJ, Atwood C, Ewing JA, Pusker SH, Cancellaro VA, Walker KB, Cobb W, Carbonell A, Morgan RR. Effect of multimodal analgesia on opioid use after open ventral hernia repair. J Gastrointest Surg. 2017;21(10):1692-9. PMID: 28808868.

256. Warren J, Love M. Incisional hernia repair: minimally invasive approaches. Surg Clin North Am. 2018;98(3):537-59. PMID: 29754621.

257. Warren J, Beffa LR, Carbonell A, Cull JD, Sinopoli B, Ewing JA, McFadden C, Crockett J, 43

Cobb W. Prophylactic placement of permanent synthetic mesh at the time of ostomy closure prevents formation of incisional hernias. Surgery. 2018;163(4):839-46. PMID: 29224706.

258. Warren J, McGrath SP, Hale A, Ewing JA, Carbonell A, Cobb W. Patterns of recurrence and mechanisms of failure after open ventral hernia repair with mesh. Am Surg.

2017;83(11):1275-82. PMID: 29183531.

259. Warren J, Carbonell A. Robotic repair of upper abdominal hernias. In: Abdallah ed. Robotic Surgery for Abdominal Wall Hernia Repair: A Manual of Best Practices. New York, NY: Springer Publishing; 2017;21-34.

260. Zielinski MD, Haddad NN, Cullinane DC, Inaba K, Yeh DD, Wydo S, Turay D, Pakula A, Duane TM, Watras J, Widom KA, Cull JD, Rodriguez CJ, Toschlog EA, Sams VG, Hazelton JP, Graybill JC, Skinner R, Yune JM. Multi-institutional, prospective, observational study comparing the Gastrografin challenge versus standard treatment in adhesive small bowel obstruction. J Trauma Acute Care Surg.

2017;83(1):47-54. PMID: 28422909.

Academy for Leadership & Professional Development

267. Bonds CL, Roudebush W, Lessey B. Sperm motility index and intrauterine insemination pregnancy outcomes. GHS Proc.

2017;2(2):125-30.

268. Emoto C, Johnson T, McPhail B, Vinks AA, Fukuda T. Using a vancomycin PBPK model in special populations to elucidate case-based clinical PK observations. CPT Pharmacometrics Sys Pharmacol. 2018;7(4):237-50. PMID: 29446256.

269. Gainey J, Wormack L, Brechtel L, Nathaniel T. Abstract WP89: A functional outcome model for a telestroke-guided tissue plasminogen activator treatment of stroke patients. Stroke.

2018;49(suppl 1):AWP89-AWP89.

270. Harmon KA, Lane BA, Boone RE, Afshari A, Berdel HO, Yost MJ, Goodwin R, Friedman HI, Eberth JF. Therapeutic engineered hydrogel coatings attenuate the foreign body response in submuscular implants. Ann Plastic Surg. 2018;80(suppl 6):S410-S417. PMID: 29746273.

261. Salas E, Vessey B, Landon L. Temporal Dynamics in Multiteam Systems: An Integrative Perspective for Future Research and Practice. Bingley, UK: Emerald Publishing; 2017:288-322.

271. Johnson AB, Montgomery CM, Dillard WA, Morrill K, Hoesli C, Gillette WM, Johnson BK, Nathaniel T. Effect of visual art schoolbased stroke intervention for middle school students. J Neurosci Nurs. 2017;49(4):214-20.

262. Shuffler Porter ML, DiazGranados D, Maynard T, Salas E. Developing, sustaining, and maximizing team effectiveness: an integrative, dynamic perspective of team development interventions. Acad Manage Ann. 2018;12(2):688-724.

272. Jones RS, Chang PH, Perahia T, Harmon KA, Junor L, Yost MJ, Fan D, Eberth JF, Goodwin R. Design and fabrication of a three-dimensional in vitro system for modeling vascular stenosis. Microsc Microanalysis.

2017;23(4):859-71. PMID: 28712382

263. Shuffler ML, Kramer WS, Carter D, Thayer A, Rosen M. Leveraging a team-centric approach to diagnosing multiteam system functioning: the role of intrateam state profiles. Hum Resource Manage Rev. 2017 Aug. http://dx.doi. org/10.1016/j.hrmr.2017.08.003.

273. Kay D, Teal C, Crites G, Berry A, Hurtubise L, Hall E, Khalil M. “Being there”: building productive scholarly teams across distance and over time. J Reg Med Campuses. 2018;1(2).

USC School of Medicine Greenville: Biomedical Sciences Faculty, Staff & Students 264. Abdel Meguid EM, Khalil M. Measuring medical students’ motivation to learning anatomy by cadaveric dissection. Anat Sci Educ.

2017;10(4):363-71. PMID: 27925681.

265. Angermayer ME, Chosed RJ, Roudebush WE. Platelet-Activating Factor protects early embryos from apoptosis. Reprod Sci. 2018;25(suppl 1):245A.

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266. Basinger J, Fiester SE, Fulcher JW. Methicillin-resistant Staphylococcus aureus parotitis leading to mortality in an adolescent male. Am J Forensic Pathol. 2018;39(3):257-60.

274. Kennedy AB, Hales S. Tools clinicians can use to help patients get active. Curr Sport Med Rep. 2018;17(8):271-6. PMID: 30095547.

275. Kennedy AB, Cambron J, Dexheimer J, Trilk J, Saunders RP. Advancing health promotion through massage therapy practice: a cross-sectional survey study. Prev Med Rep. 2018 Sep;11:49-55. PMID: 29984138.

276. Kennedy AB, Patil N, Trilk J. “Recover quicker, train harder, and increase flexibility”: Massage therapy for elite paracyclists, a mixed methods study. Br Med J Open Sports Exerc Med. 2018;4(1):e000319. PMID: 29387449.

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2018 PUBLICATIONS 277. Kennedy AB, Lavie CJ, Blair SN. Fitness or fatness: which is more important? JAMA. 2018;319(3):231-2. PMID: 29340689.

278. Khalil M, Abdel Meguid EM, Elkhider IA. Teaching of anatomical sciences: a blended learning approach. Clin Anat. 2018;31(3):323-9.

279. Khalil M, Hawkins HG, Crespo L, Buggy J. The design and development of prediction models for maximizing students’ academic achievement. Med Sci Educator.

2018;28(1):111-7. PMID: 29352730.

280. Khalil M, Williams S, Gregory Hawkins H. Learning and study strategies correlate with medical students’ performance in anatomical sciences. Anat Sci Education. 2018;11(3):236-42.

281. Lane BA, Harmon KA, Goodwin R, Yost MJ, Shazly T, Eberth JF. Constitutive modeling of compressible type-I collagen hydrogels. Med Eng Phys. 2018;53:39-48. PMID: 29396019.

282. Longan E, Knutsen M, Shinkle J, Chosed R. Adapting a photochemical reactor to the study of UV ecology in vineyard yeast. Am J Enol Vitic. 2017;68(4):499-503.

processes and virulence factors in Acinetobacter baumannii. PLoS ONE. 2018;13(1): e0190599.

288. Olaleye T, Muse W, Adekanbi S, Isang D, Alabi I, Imeh-Nathaniel A, Nathaniel T. Biological effects of petiveria alliacea and flueggae virosa on the life cycle of a disease vector. Asian Pacific J Tropical Dis. 2017;5(1):45-51.

289. O’Rourke MA, O’Rourke MC, Hudson MF. Reasons to reject physician assisted suicide/physician aid in dying. J Oncol Pract.

2017;13(10):683-6.

290. Pendergrass J, Stewart B, Williams K, Buggy J, Black A, Jain S, Hughes M, Troup C, Nathaniel T. Integration of patients into first-year neuroscience medical curriculum. Health Professions Education. 2018;4(1):59-66.

291. Polk SR, Stafford C, Adkins A, Effird J, Colello M, Nathaniel T. Contraindications with recombinant tissue plasminogen activator (rt-PA) in acute ischemic stroke population.

Neurol Psychiatry Brain Res. 2018;27:6-11.

283. Morgan KM, Northey EE, Khalil M. The effect of near-peer tutoring on medical students’ performance in anatomical and physiological sciences. Clin Anat. 2017;30(7):922-8. PMID:

292. Rotimi OR, Kuku O, Kalu N, Oni O, Nwabueze C, Nathaniel T, Zheng S, et al.

Association between smoking and functional outcome in acute ischemic stroke population treated with tissue plasminogen activator. Clin Epidemiol Commons. 2018 Apr.

284. Nathaniel T, Gainey J, Wormack L, Ubah C, Brechtel L, Frazier A. Abstract P532: Hypertension and gender differences in acute ischemic stroke patients treated with rtPA. Hypertens. 2018;70(suppl 1):AP532.

293. Rule KN, Chosed RJ, Chang TA, Robinson RD, Wininger JD, Roudebush WE. Blastocoel cell-free DNA, a marker of embryonic quality.

Fertil Sterility. 2017;103(3)(suppl):e106.

28726243.

285. Nathaniel T, Gainey JC, Williams JA, Stewart BL, Hood MC, Brechtel LE, Faulkner RV, Pendergrass JS, Black LA, Griffin SK, et al.

Impact and educational outcomes of a small group self-directed teaching strategy in a clinical neuroscience curriculum. Anat Sci Education. 2017;11(5):478-87.

286. Nathaniel T, Stewart B, Williams J, Hood M, Imeh-Nathaniel A. A new insight into the ability to resist ischemic brain injury: does hibernation matter? An editorial comment for “Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernation season even when not hibernating and after ATP depletion, acidosis and glutamate efflux.”

J Neurochem. 2017;142(1):10-3.

287. Ohneck EJ, Arivett BA, Fiester SE, Wood CR, Metz ML, Simeone GM, Actis LA. Mucin acts as a nutrient source and a signal for the differential expression of genes coding for cellular

GHS Proc. December 2018; 3 (1): 31-46

294. Rule KN, Chosed RJ, Chang AT, Wininger JD, Roudebush W. Relationship between blastocoel cell-free DNA and day-5 blastocyst morphology. J Assist Reprod Genet. 2018;35(8):1497-501.

295. Rule KN, Chosed RJ, Chang AT, Wininger JD, Roudebush W. Blastocoel cell-free DNA, a marker of embryonic quality. Fertil Sterility.

2017;108(3):245A. 296. Rumbo-Feal S, Pérez A, Ramelot TA, Arivett BA, Beceiro A, Vallejo JA, Álvarez-Fraga L, Merino M, Ohneck EJ, Fiester SE, Kennedy MA, Actis LA, Bou G, Poza M. Contribution of A. baumannii A1S_0114 gene to the interaction with eukaryotic cells and virulence. Pseudomonas and Acinetobacter: From Drug Resistance to Pathogenesis. Frontiers. 2018 Apr;103-116.

297. Russ-Sellers R, Blackwell T. Emergency medical technician training during medical school: benefits for the hidden curriculum. Academic Med. 2017;92(7):958-60. PMID: 28145946.

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298. Shipley AT, Imeh-Nathaniel A, Orfanakos VB, Wormack LN, Huber R, Nathaniel T. The sensitivity of the crayfish reward system to mammalian drugs of abuse. Frontiers Physiol. 2017;8:1007.

299. Wapshott T, Blum B, Kelsey W, Nathaniel T. Investigation of gender differences and exclusive criteria in a diabetic acute ischemic

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stroke population treated with recombinant tissue-type plasminogen activator (rtPA). J Vascular Intervent Neurol. 2017;9(6):26.

300. Wright W, Baston K. Use of the NBME basic science subject exams in US medical schools: results of a national survey. Adv Med Educ Pract. 2018 Aug;9:599-604.

GHS Proc. December 2018; 3 (1): 31-46

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December 2018 | Volume 3 | Issue 1

Special Articles 5

A Selection of Abstracts Presented at the 2018 GHS Health Sciences Center Research Showcase

23 Full List of Abstracts Presented at the 2018 GHS Health Sciences Center Research Showcase

Miscellany 29 2018 Greenville Health System Residents and Fellows 30 2018 Graduates of Greenville Health System and University of South Carolina School of Medicine Greenville 31 Publications and Abstracts of Greenville Health System Medical and Scientific Staff, July 2017-June 2018

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