LabMedica International September 2016

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W O R L D ’ S C L I N I C A L L A B O R AT O R Y N E W S L E A D E R ISSN 1068-1760

Vol. 33 No. 5 • 8-9/ 2016

DAILY CLINICAL LAB NEWS

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Urine Dipstick Test For Malaria Diagnosis

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Molecular Diagnostics Identifies Resistance Biomarkers of Bloodstream Infection

alaria is the world’s most important tropical parasitic disease and a leading cause of death worldwide and the disease is caused by the parasite, Plasmodium species and transmitted to humans by infected mosquitoes. Symptoms include fever and usually appear 10 to 15 days after someone is bitten by an infected mosquito.

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olecular diagnostics allow for rapid identification and detection of resistance markers of bloodstream infection, with a potential for accelerated antimicrobial optimization and improved patient outcomes. Bloodstream infections (BSIs) are associated with significant health care cost and prolonged hospital stays.

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Rapid initiation of effective antimicrobial treatment is a mainstay of therapy because delay is associated with increased morbidity and mortality. Novel methods that allow for rapid identification of pathogens, with the ability to detect resistance markers, are, therefore, promising tools to significantly affect overall patient care.

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IVD Industry Mobilizes to Provide Zika Diagnostics

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Blood Clots Detected By Simple POC Test atients with cardiovascular disease, hypertension, atrial fibrillation, congestive heart failure, kidney disease and others who are at risk for blood clotting are especially vulnerable when blood-thinning medication levels get too weak or too strong. A test has been designed to give each patient the ability to keep a careful check on their levels by monitoring the changes that occur relative to previous tests. The technology can also be

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Novel Blood Biomarker Identified for Autism

Special Section: Zika Update (Pages 8-11)

arly intervention is the key to the best treatment for autism spectrum disorder (ASD), which affects about 1 in 70 children. Unfortunately, most children are not diagnosed until about age four, when communication and social disabilities become apparent. Blood biomarkers have been identified that could distinguish the majority of ASD study participants versus a control group of similar age range. In

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New Optimized Tests for Reliable Zika Diagnosis High-Resolution Zika Detection With CRISPR Technology Image: Courtesy of EUROIMMUN

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Urine Trumps Blood For Zika Testing Zika Test Cleared for Emergency Use Multiplex Molecular Test For Three Arboviruses

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System Improves Accuracy of Low Cell Counts in Cerebrospinal Fluid Samples new technology offers quantitative determinations of red blood cells (RBCs) and total nucleated cells (TNCs) in Cerebrospinal Fluid (CSF), thereby greatly improving on the challenges of diagnosing low cell counts.

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Blood Marker Determines Response To Colorectal Cancer Drug

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marker has been identified that shows up in a blood test that determines which patients with colorectal cancer that has metastasized would benefit from receiving the drug cetuximab. Only a proportion of patients with colorectal cancer receiving cetuximab derive benefit from the drug; however,

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other than the Rat sarcoma gene(RAS) and B-RAF oncogene (BRAF) mutations, no biomarkers have been identified as clinically useful predictors of response to cetuximab. Scientists at the Princess Margaret Cancer Centre (Toronto, ON, Canada; www.uhn.ca) and their international Cont’d on page 7

INSIDE Clinical News . . . . . . . . . 4-26 IFCC News . . . . . . . . . . . . . 27 EFLM Corner . . . . . . . . . . . 30 Product News . . . . . . . . 6-26 Industry News . . . . . . . . . .33 International Calendar . . . 34 PUBLISHED IN COOPERATION WITH

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