Penn Medicine and Covid-19

Global Interdependence Center: Artificial Intelligence/Machine Learning Penn Medicine and Covid-19

John P. Donohue Vice President, Information Services October 6, 2020

Penn Medicine Regional Market Penn Medicine Market Inpatient, OutpatientRegional and Home Care Settings Princeton Health

LGH CCH

UPHS Hospital

UPHS Satellites

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Informaton

Om n n Pe

Data

VALUE

Knowledge

Leveraging Technology Platforms to Drive Value

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2006

Implement the PennChart Platform Facilitated Data Analytcs First Generaton Research Computng Support

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2010

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2014

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m or & tf e a Pl rm or t n h o S I rc atfo ili ata – A a v a D ng se t Pl P e n nt en ut e al R en e P p n n m t Pa cs – Com dici ato age w t e e sl an Ne naly itv n M ran l M • A gn io T ita • Co ecis al & ap • Pr nic n C • Cli ma e • Hu rvic • Se •

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2020

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COVID-19 IT Activities • Transitioned 20,000+ Employees to Remote Work Environment • Deployed Enterprise Administrative Video Conferencing • Introduced Over 1,000 Surge Beds and 250+ ICU Beds • Opened Several Community Drive-up COVID-19 Testing Sites • Adapted PennChart to support COVID-19 Alerts and Protocols • Provisioned Rapid Result COVID-19 Laboratory Tests • Supported Accelerated Clinical Trials • Developed MeNTS Scoring, Penn OpenPass, Thermal Scanning, Contact Tracing Tools • Rolled Out Enterprise Telemedicine Solution • Enhanced Information Security Controls • Developed Capacity and Resurgence Analytics

Penn Medicine’s CHIME Program The CHIME (Covid-19 Hospital Impact Model for Epidemics) program was created to enable Penn Medicine and other healthcare systems to explore possible COVID-19 patient surge scenarios to generate a pandemic strategy and response.

Approach: 

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Penn Data Science partnered to create the Penn-CHIME application (Deployed March 14) • UPenn Department of Epidemiology and Biostats •

CodeForPhilly: Program Management, Data Scientists, and Software Developers (45 Contributors)

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Linode.com: Hosted CHIME application

Organized People and Process to ensure the best knowledge to drive analysis and reports • Penn Medicine Analyst team comprised of representatives from each entity (LGH, CCH, PMC, HUP, PAH, MCP) •

Wharton LDI, Epi and Biostat department to research publications and regional reports

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Penn, Jefferson and Philadelphia Health Commissioner weekly collaborations to share regional information

Outcomes: 

Provided to Entity and Department decision makers to adapt process and analysis Impact

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Penn Medicine used CHIME to inform decisions on PPE, equipment purchases, facility planning, and staff scheduling

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Penn Data Science team worked directly with state government officials in CA, SC, NC, numerous counties and health systems, as well as FEMA.

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>55K users worldwide – Over 100 articles citing CHIME – Publications in JAMA and Annuals of Internal Medicine

Penn-CHIME Application S.I.R. CHIME App

Penn Analysis and Reporting

Enabling health system planners to create plausible scenarios based on regional data

Use CHIME app and best estimates of current conditions to explore scenarios from best to worst case to guide planning efforts

Evolution of Penn-CHIME Application

Penn Medicine needed to understand the likelihood of trajectories, resulting in the development of BayesCHIME. The team used Machine Learning and statistical models to enhance the tool.

SIR CHIME Model Limitations

April 7 - Bayesian CHIME Model

Manual selection of pandemic parameters Created Scenario Boundaries Only one modeled pandemic peak

Enabling health system planners the ability to create likely pandemic trajectory and future what-if scenarios

CHIME Modeling Examples Assessment Against Analyst Intuition and Regional Reports Rt < 1, new cases decreasing Rt > 1, new cases increasing

Non-Pharmaceutical Intervention Reduction

Other Cognitive Computing Initiatives • Covid Watch • Text Messaging Tool • Designed to allow Penn Med providers to “watch over” Covid-19 patients not requiring hospitalization • Used by over 1,000 patients • Twice a day check-ins for each patient • Learning engine for follow up questions based on patient responses • Telemedicine referrals based on patient’s healthcare needs

• Covid-19 Chatbot • • • •

AI Powered Chatbot Initiated from Penn Medicine’s Covid-19 web page Powered by Google’s Chat Bot Engine Designed to expedite Covid-19 communication with community • Symptom checker capability or Covid-19 questions • Great feedback from patients and employees • Still in use today

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