Pharmaceutical company AstraZeneca focuses its global community investment on the pressing challenge of preventing non-communicable diseases. They do this by targeting adolescents health and major risk behaviours such as tobacco and alcohol use and unhealthy eating through the AstraZeneca Youth Health Programme. A unique feature of the programme is that combines measures for behavioural change with research and advocacy. In this Deep Dive, we delve deeper into the Youth Health Programme in order to understand its background story and key features.