05/05/2011
Contents • Aims and objectives • Glycolysis • TCA cycle • Insulin and glucagon
Metabolism
• Fed state
Created by Sophia Oxenburgh ©
• Fasting state • Summary
Aims and Objectives • For each metabolic pathway have an awareness of: – Substrate and product – Important enzymes – Main regulatory mechanisms
• An understanding of how pathways fit together • An understanding of the differences between fed and fasting states
Quick Reminder
Glycolysis • First step of cellular
Brain
Muscle
Glucose
Glucose
Ketone bodies
Ketone Bodies Fatty acids
respiration • There are LOTS of steps • Regulated by – hexokinase – PFK-1 – pyruvate kinase
• Aerobic v anaerobic
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