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to generate simulation data. Time and frequency domain issues will be addressed. Students will use MATLAB computer methods to solve problems in human physiology, data analysis, system identification, and model validation. Basic control principles will be introduced. Prerequisites: ECE 231 (or ECE 228) (may be taken concurrently), BME 355 3 credits, Spring BME 440: Bioengineering Lab Laboratory experiences with measurements of human physiological variables for medical devices including the application of statistical techniques. Prerequisites: BIOL 124 (or BIOL 117), ME 205-206 (or ECE 105-106) 1 credit, Fall BME 454: Tribology This course addresses the design of tribological systems: the interfaces between two or more bodies in relative motion. Fundamental topics include geometric, chemical, and physical characterization of surfaces; friction and wear mechanisms for metal, polymers, and ceramics, including abrasive wear, delamination theory, tool wear, erosive wear, wear of polymers and composites; and boundary lubrication and solid-film lubrication. The course also considers the relationship between nano-tribology and macro-tribology, rolling contracts, tribological problems in magnetic recording and electrical contracts, and monitoring and diagnosis of friction and wear. Case studies are used to illustrate key points. Prerequisites: ME 315, BME 310 3 credits, Fall BME 460: Biosignal Processing In this course, students will learn how to design and choose a filter for processing signals commonly collected in Biomedical Engineering (e.g. electromyography, electrocardiogram, forceplate data). Topics to be covered include FIR filters, IIR filters, Butterworth filters, and residual analysis. Signal processing will be performed using user-generated code to understand how these filters are practically implemented. Prerequisites: PHYS 214 (or ECE 228), BME 355 3 credits, Fall BME 462: Surface Science and Engineering This course provides an introduction to surface properties of materials and an overview of electron microscopy, surface analysis techniques, adhesion and adhesive bonding technology. The course emphasizes conceptual understanding as well as practical industrial-related applications of the material. Topics covered include surface properties of materials, surface wettability and surface tension, surface modification treatments, microscopy and surface analysis techniques, adhesion, adhesive bonding and related industrial applications, bond failure investigations and failure analysis. Prerequisites: ME 315, BME 310 3 credits, Spring BME 465: Biomedical Heat and Mass Transfer This course is an introduction to biomedical heat and mass transfer. The relevant principles of heat transfer will be reviewed. Macroscopic and microscopic approaches to biomedical heat transfer will be covered. An introduction to mass transfer and its applications in biomedical and biological systems will be presented. Prerequisites: PHYS 212, BME 310 3 credits BME 466: Energy Storage Systems In this course energy storage techniques such as thermal, electrochemical, mechanical, and electromagnetic as well as energy storage in organic biofuels will be covered. Different energy storage methods will be compared in terms of cost, size, weight, reliability and lifetime. The differences, advantages, disadvantages and variety of applications of these techniques will be presented. Specific emphasis will be placed on biomedical systems such rehabilitation systems, implantable and wearable devices. Prerequisites: PHYS 214, BME 310 3 credits BME 467: Biofluid Mechanics This course introduces fundamental physical concepts and mathematical equations describing the dynamics of fluid flows and their application to biomedical problems. At the completion