FJ Portfolio

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Massachusetts Institute of Technology

2019 Lab of the Year Award

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MIT.nano

WEAVING INTO CAMPUS

MIT’s campus in Cambridge, MA sits along the north edge of the Charles River. It forms a triangle with the academic core at the center. MIT.nano is located here.

MIT.nano consolidates complex research and learning activities from across the institution, organizes them to maximize collaboration, creates new indoor and outdoor social space, weaves into the fabric of MIT physically and academically.

TRANSFORMING THE PRECINCT

MIT.nano transforms this important precinct from a service yard to a series of connected outdoor campus yards.

view from the Main Group of the Building 12 (left) the site of MIT. nano and Improbability Walk.

2 CAMBRIDGE
BOSTON MIT.nano Legend 1. MIT Campus 2. Kendall Square 3. Charles River 4. Harvard University LOCUS PLAN Legend 1. Infinite Corridor 2. Improbability Walk 3. Northwest Passage (Breezeway) 4. North Corridor
4 2 1 3 1 2 3 4
The

MIT.nano creates a new entrance and connection at what was a service yard behind the historic Main Group. A pedestrian friendly series of lush outdoor spaces link ‘Improbability Walk’ on the south via a breezeway featuring a site specific art installation ‘Northwest Passage’ by a renowned artist.

PLAN

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Legend 1. MIT.nano 2. Great Dome 3. Killian Court 4. Main Group Buildings 5. Improbability Walk 6. North Corridor
SITE
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ENTRANCE AND BREEZEWAY
2 3 4 4 6 5

51% Source Energy Savings

GLASS VEIL

The glassy veil selectively cloaks and reveals what is behind. Those walking outside have clear views into the machine. Cuts within the veil mark the central spine of the stacked cleanrooms and provide a view corridor from the North Corridor to Improbability Walk beyond. Spaces that push beyond this veil set up views of the gowning process within, and the Dome and campus beyond.

STONE BOX

The volume and materiality of the core facility recall the weight and gravity of the dome. The top of MIT.nano was carved to preserve critical views of the Dome from around Campus. Cuts in the stone invite students and visitors to observe the research directly, through large windows into the cleanroom and the mechanical systems that serve it.

4 PENTHOUSE LEVEL 1 CLEANROOM & FAN DECK LEVEL 2 CLEANROOM & FAN DECK CHEMISTRY TEACHING & NANO MAKER SPACE IMAGING / SUBFAB Building Envelope Green Space Energy Recovery Lab Ventilation

MATERIALS SCIENCE

Façade materiality was inspired by the building program. Manipulation of atomic structures relies on layering, etching, deposition and interaction with light. MIT.nano’s facade materials conceptually reference these processes. Sedimentary limestone cladding evokes the layering of atoms. Etched and fritted glass mimics the deposition and coating of microelectronic wafers.

5'-3" UNIT SIZE 6'-3" UNIT SIZE OFF ON/OFF ON ON/OFF ON ON/OFF OFF ON/OFF ON ON/OFF 5'-3" UNIT SIZE 6'-3" UNIT SIZE OFF ON/OFF ON ON/OFF ON ON/OFF OFF ON/OFF ON ON/OFF 1'-6" 4'-0" 4'-0" 4'-0" 4'-0" 1'-6" 2'-0" 3 3 4 3 3 4 3 3 4 4" 4" 4" 3 5 STONE COURSING
FIBER CEMENT STONE DOME VEIL
GLASS VEIL LAYERS AND ETCH PATTERN FIBER CEMENT BOARD COURSING WAFER
6 11th Floor Conversion to Lab Broad Institute of MIT and Harvard

OPEN LAB OPTIONS

NEEDFINDING & DESIGN THINKING

• Conversion of 30,000 SF floorplate from office to lab

• Engaged “surrogate” lab users to guide the design

• 8,000 SF open lab with natural daylighting

• 6,000 SF of lab support: tissue culture rooms, cold rooms, microscopy, procedure room, and freezer farm

• Sustainable products

• Introduction of new design approaches: Power BI & Miro Board

Add accent color Replace  this carpet  as it's too  gray www.bentleymills.com Design Detail - Bentley Mills K64  or K021 1  1  2  3  1  2  3  2  3  1  2  3  First Option: Wilsonart North Sea 090-60 photographs darker in the  above image when it's directly on  the carpet, but here you hold above the ground as would be  installed doesn't read as dark. It's bit  too cool  of  gray This is  second  option that  could work. | 26 HGA 04.01.21
Option 1 7
Option 2 (Mondo Kayar K064) Option 2 (Mondo Kayar K021)
NSF Ratio per Depar tment Type 59% 14% 22% 3% 1% Program Platform Core Member Comp/Admin Admin w/ Lab GSF & Pr og r ammed NSF 0 5,000 10,000 15,000 20,000 25,000 30,000 75A-PH 75A-12 75A-M1 75A-11 75A-10 75A-09 75A-08 75A-07 75A-06 75A-05 75A-04 75A-03 75A-02 75A-01 75A-B 21,510 10,000 158 3,741 16,940 17,405 17,084 17,030 18,698 12,057 8,835 8,472 8,835 8,835 322 24,696 28,659 27,667 28,659 28,659 28,659 28,659 30,287 30,287 15,736 15,736 15,736 15,736 9,955 13,304 Other NSF (Comp/Adm n/Vivar) Programmed NSF GSF Total NSF per Depar tment Type 0K 10K 20K 30K 40K 50K 60K 70K Program Platform Core Member Comp/Admin Admin w/ Lab 67.67K 16.20K 25.05K 3.74K 1.39K March 3, 2022 Ratio of NSF to GSF 0% 100% 50% GSF 342K NSF 170K NSF includes Programmed NSF & Other NSF 8 BENCHMARKING METRICS
RATIO OF L AB TO L AB SUPPORT 0% 100% 63% OPEN L AB NSF / BP 71 83 75 Ames Avg Open Lab NSF / BP 11th Floor Open Lab NSF / BP 83 DESKS / BP 2.0 1.1 75 Ames Avg Desks / BP 11th Floor Desks / BP 1.1 OFFICE & WORKSTATION NSF / DESK 41 39 75 Ames Avg NSF / Desk 11th Floor NSF / Desk ASSIGNED NSF / PERSON 76 112 75 Ames Avg Assigned NSF / Person 11th Floor Assigned NSF / Person 82 BENCH POSITIONS ASSIGNED IN OPEN L AB 93 DESKS OPEN, SHARED, PRIVATE, FLEX 17,097 NSF 184 NSF
PERSON 39 112 COMBINED L AB & NON-L AB PERSONNEL TOTALS 6,807 Open Lab NSF Lab Support NSF 4,053 Office Support NSF 2,649 Office NSF 3,588 RATIO OF OFFICE TO OFFICE SUPPORT 0% 100% 58% Office NSF Laboratory NSF 6,237 10,860 RATIO OF L ABORATORY TO OFFICE 0% 100% 64% Dashboard 11 August 2021 9 PROJECT DASHBOARD
/
Combined Plans O O O O RATIO OF LAB TO LAB SUPPORT 0% 100% 56% RATIO OF OFFICE TO OFFICE SUPPORT 0% 100% 63% RATIO OF LABORATORY TO OFFICE 0% 100% 61% OPEN LAB NSF BP 71 75 75 Am s Avg Ope L b NS P 1 h Floor Ope L b N F P 75 DESKS BP 2.0 1.5 5 Ame A g De s / BP 11 Floor D s B 1.5 OFFICE & WORKSTATION NSF / DESK 41 37 5 Ame A g NS De 1 h Floor NSF/ D k ASSIGNED NSF / PERSON 76 87 5 Ame A g A g ed N F e on 1 h Floor As ne NS P son L yotarob Office OpenLab oppuSbaL O f f c OfficeSuppo t 61% Pct of Laboratory 84 BENCH POSITIONS ASSIGNED IN OPEN L AB 126 DESKS OPEN, SHARED PRIVATE, FLEX 18,741 NSF 148 NSF / PERSON 37 87 COMBINED AB & NON-LAB PERSONNEL TOTALS 6,318 Open Lab NSF 5,044 Lab Suppor NSF Office NSF 4,617 Office Suppor NSF 2,762 Laborator y NSF 11,362 Office NSF 7,379 Option A Dashboard RATIO OF LAB TO LAB SUPPORT 0% 100% 56% RATIO OF OFFICE TO OFFICE SUPPORT 0% 100% 57% RATIO OF LABORATORY TO OFFICE 0% 100% 56% OPEN LAB NSF / BP 71 75 7 Ame A g Op n a N F / BP 11 Floor Op n a NS BP 75 DESKS / BP 2.0 1.5 75 Am s Avg D k B 1 h Floor De k P 1.5 OFFICE & WORKSTATION NSF / DESK 41 40 75 Am s Avg N F D k 1 Floor NSF/ De ASSIGNED NSF / PERSON 76 90 75 Am s Avg As ne NS P son 1 h Floor A gn d NS e on L a b r a yrot O f f ice OpenLab oppuSbaL ffO i ec OfficeSuppor 56% Pct of Laboratory 77 BENCH POSITIONS ASSIGNED IN OPEN L AB 116 DESKS OPEN, SHARED PRIVATE, FLEX 18,351 NSF 159 NSF / PERSON 40 90 COMBINED LAB & NON-LAB PERSONNEL O ALS 5,788 Open Lab NSF 4,462 Lab Suppor NSF Office NSF 4,648 Office Suppor NSF 3,453 Laborator NSF 10,250 Office NSF 8,101 Option B Dashboard RATIO OF LAB TO LAB SUPPORT 0% 100% 57% RATIO OF OFFICE TO OFFICE SUPPORT 0% 100% 59% RATIO OF LABORATORY TO OFFICE 0% 100% 59% OPEN LAB NSF BP 71 75 75 Am s Avg Ope L b NS P 1 h Floor Ope L b N F P 75 DESKS BP 2.0 1.5 5 Ame A g De s / BP 11 Floor D s B 1.5 OFFICE & WORKSTATION NSF / DESK 41 36 5 Ame A g NS De 1 h Floor NSF/ D k ASSIGNED NSF / PERSON 76 86 5 Ame A g A g ed N F e on 1 h Floor As ne NS P son aL otarob y O f fice OpenLab oppuSbaL fO f i ec OfficeSuppo 59% Pct of Laboratory 80 BENCH POSITIONS ASSIGNED IN OPEN L AB 120 DESKS OPEN, SHARED PRIVATE, FLEX 17,811 NSF 149 NSF / PERSON 36 86 COMBINED AB & NON-LAB PERSONNEL TOTALS 5,990 Open Lab NSF 4,442 Lab Suppor NSF Office NSF 4,364 Office Suppor NSF 3,015 Laborator y NSF 10,432 Office NSF 7,379 Option C Dashboard RATIO OF LAB TO LAB SUPPORT 0% 100% 67% RATIO OF OFFICE TO OFFICE SUPPORT 0% 100% 63% RATIO OF LABORATORY TO OFFICE 0% 100% 61% OPEN LAB NSF / BP 71 75 7 Ame A g Op n a N F / BP 11 Floor Op n a NS BP 75 DESKS / BP 2.0 1.2 75 Am s Avg D k B 1 h Floor De k P 1.2 OFFICE & WORKSTATION NSF / DESK 41 37 75 Am s Avg N F D k 1 Floor NSF/ De ASSIGNED NSF / PERSON 76 97 75 Am s Avg As ne NS P son 1 h Floor A gn d NS e on yrotarobaL Office O pen L b ba oppuS O f f c e OfficeSupport 61% Pct of Laboratory 101 BENCH POSITIONS ASSIGNED IN OPEN L AB 126 DESKS OPEN, SHARED PRIVATE, FLEX 18,807 NSF 149 NSF / PERSON 37 97 COMBINED LAB & NON-LAB PERSONNEL O ALS 7,600 Open Lab NSF 3,828 Lab Suppor NSF Office NSF 4,617 Office Suppor NSF 2,762 Laborator NSF 11,428 Office NSF 7,379 Option D Dashboard BROAD INSTITUTE 75 Ames St / December 10 OPTIONS COMPARISON
11 300 Binney Street Renovation & Fitout Broad Institute of MIT and Harvard

SCENARIO PLANNING & LEASING OPPORTUNITY COMPARISON

• What is the optimal amount of space for Broad expansion?

• How many program, core member, and platform groups would be supported?

• How much additional computational and administrative space is optimal?

OPPORTUNITY 1

2 - 250,000 RSF

SCENARIO 3 - 300,000 RSF

1 Rentab e Square Feet (RSF) = Tenant's Useable Square Feet plus the al ocated port on of Base Bui ding and Common Areas, such as lobby load ng and mechanica penthouse

2 Useable Square Feet (USF) = Floor areas outside of Base Building areas, such as building core

3 Load Factor=RSF/USF. For general planning purposes, a Load Factor of 1 30 s assumed

4 Net Square Feet = Program space required for a particu ar function exclusive of corr dors amenity conference and interior & exter or wal s

5 NSF / USF Efficiency is based on 75 Ames analys s

6 Coll ns Lab research group is included under Program as the closest category

7 Comp/Admin does not have assigned community or meeting space.

OPPORTUNITY 2

1 B1 PARK | LOAD 10 PARKING LOBBY | RETAIL 2 4 5 6 7 8 LAB | OFFICE 9 LAB OFFICE LAB | OFFICE LAB | OFFICE LAB | OFFICE COMMUNITY Terrace 3 LAB OFFICE LAB | OFFICE CHEMISTRY LAB ELEC | MDF OFFICE OFFICE OFFICE MECH M2 11 12 13 M1 MECH Consider Analytical Chemistry or similar for  2nd 3rd Floors: high MAQ solvent limits  Consider Comp uses for upper floors:  lower MAQ solvent Reduced floorplate size Consider H ooms: MAQ solvent limits 6th floor B2 PARKING B3 PARKING HGA DRAFT TENANT EQUIP TENANT  EQUIP HGA 1 PARK | LOAD LOBBY | COMMUNITY 2 4 5 6 LAB | OFFICE 3 LAB | OFFICE MECH | TENANT EQUIP M1 HGA DRAFT LAB | OFFICE LAB | OFFICE LAB | OFFICE EQUIP SCREEN Extents of PH and Scr are TBD R S F 200K SCENARIO 1 - 200,000 RSF U S F 154K N S F 96,823 19 365 116K U S F 192K N S F 121,029 24 206 145K R S F 250K U S F 231K N S F 145 235 29 047 174K R S F 300K SCENARIO
20,664 Core Member NSF Core Member Qty Program NSF Program Qty 49,626 P atform NSF Platform Qty 13,363 Sw ng Space NSF 8,872 3 6 3
Column1
March 3, 2022 20,664 Core Member NSF Core Member Qty Program NSF Program Qty 66,168 Platform NSF P atform Qty 13,363 Sw ng Space NSF 15,438 3 8 3 27,552 Core Member NSF Core Member Qty Program NSF Program Qty 82,710 Platform NSF P atform Qty 17,817 Sw ng Space NSF 10,663 4 10 4 34,440 Core Member Qty Program Qty 99,252 P atform Qty 22,271 Swing Space NSF 5,887 5 12 5 U S F 269K R S F 350K SCENARIO 4 - 350,000 RSF N S F 169,441 33 888 203K Load Factor  1.30 Growth  20% NSF / USF Efficiency 76% 6,888 NSF per Core Member 8,271 NSF per Program 4,454 NSF per Platform 91 NSF per Comp/Admin Seat Comp/Admin Seat 47 Comp/Admin NSF 4,298 Comp/Adm n NSF Comp/Admin Seat 5,395 59 Comp/Admin Seat 71 Comp/Adm n NSF 6,493 Comp/Adm n Seat 83 7,590 Decompression 10% 203 NSF/Program Seat 126 NSF/Core Seat 343 NSF/Platform Seat 170 788 65 83 Core Member NSF&Person Program NSF&Person Platform NSF&Person Comp/Admin NSF&Person 12

OFFICE-TO-LAB CONVERSION AND EXPANSION

The Broad Institute is converting an existing 6-story office building into mix use of lab, office and community space.

The building was structurally designed to accommodate lab space, with a floor-to-floor height of 14’-10” and a load capacity of floors of 100 – 125 psf. However, existing Base Building mechanical, electrical, and plumbing systems were designed to accommodate office only, which need to be replaced to support lab space for 60/40 lab/office on all floors. New systems will include new equipment on the roof and within a new Base Building mechanical penthouse. The existing service elevator will be extended to serve the mechanical penthouse.

A monumental stair in the new lobby will visually and programmatically connect to community space on Level 2. Community space will include a multi-purpose Meeting Hall for symposia, dinners, and training sessions. Pre-function, collaborative spaces, and café adjacent to the Meeting Hall will provide reconfigurable area for informal collaboration, cocktail receptions, and meeting breakout space.

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TENANT EXTERIOR IMPROVEMENTS

• New 2-story entry vestibule

• New terrace on Level 3 on top of entry vestibule

• New stair connector in projecting bay on Level 4 and 5

• New terrace on Level 6 on top of projecting bay

• Pergola above Level 6 terrace, anchored to Base Building penthouse

• Terracotta screen on east façade

EXISTING VS PROPOSED MASSING OF PENTHOUSE LOWER SCREEN HEIGHTS

PROPOSED ROOF SCREEN & PENTHOUSE EXISTING ROOF SCREEN

PROPOSED 15’ ROOF SCREEN

TERRACOTTA BAGUETTE
TERRACOTTA COLOR
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TERRACOTTA BAGUETTE SCREEN TERRACOTTA RAINSCREEN CLADDING
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Confidential Fitout SmartLabs

STACKING OPTIONS AND CODE RATIONALE

The program has the following major areas with use of hazardous materials:

• cGMP

• Vivarium/ Innovation Suites

• Scaling Suites

Several options were considered for “stacking” the program floor-by-floor. Primary drivers in the development of these options included maximum allowable quantities of chemicals and solvents (MAQ’s) by floor and cGMP proximity to penthouse and roof areas. Option 8 was chosen with the vivarium on Level 5 and cGMP on Level 6.

AREA SUMMARY

CONFIDENTIAL AND PROPRIETARY revised for 9/28/21 cGMP session OCCUPANCY  GROUP 3 MECHANICAL RODI / VAC / CDA SCALING SUITES OFFICE INNOVATION LABS OFFICE VIVARIUM cGMP STORAGE /  WASTE / GAS 2 1 -1 4 6 7 8 Autoclave and  Glasswash Roof Deck  and Cafe Current CONF. / CAFE /  SL OFFICE DATA ST. SCALING SUITES OFFICE B  B + A B B B B B B+ H STORAGE SCALING SUITES OFFICE 5 cGMP  SUP OFF 0K 5K 10K 15K Basement L1 L2 L3 L4 L5 L6 L7 6.5K 6.5K 6.8K 5.5K 3.7K 1.4K 16.5K 1.8K 1.8K 1.8K 1.8K 2.8K 1.2K 1.2K 1.2K 1.2K 5.0K 5.0K 5.0K 2.6K 1.2K Lab Lab Support V var um cGMP Cafeter a Conference Off ce Off ce Support IT 23 Decembe 2021 UPDATED 12 23 21 PLANS Lab 25K (29%) 3K (3%) 4K (5%) cGMP 18K (21%) Cafeteria 10K (11%) 5K (6%) Office 19K (22%) Office Support 1K (1%) 2K (2%) Lab Support Vivarium Conference IT 58.0% Pct Laboratory of Total Laboratory Office DESCRIPTION  NSF (program areas) are updated based on Design Development as revised on 12/23/21. Updates include: revision of basement & L1, Glasswash & Biowaste in core area, relocation of Surgery & Imaging. Total NSF Total USF Efficiency Conference NSF cGMP NSF Vivarium NSF Lab NSF 25,236 3,928 18,344 5,030 86,869 113,267 77% NOTE: 1 USF: USF = RSF - BASE BUILD NG AREAS PER PREM SE SPACE ON 2021-06-23 AREAPLANS PER LEASE 2 NSF: THE PROGRAM SPACE REQU RED FOR A PARTICULAR FUNCTION EXCLUSIVE OF NTERIOR AND EXTERIOR WALLS AND NON-cGMP C RCULAT ON SPACE 3 LOAD FACTOR = RSF DIV DED BY USF 4 OFFICE SUPPORT NCLUDES WELLNESS PHONE ROOM RECEPTION OFFICE STORAGE RECYCL NG/TRASH ROOM 5 LAB SUPPORT DOES NOT INCLUDE TC INS DE SCAL NG OR NNO SU TE
Laboratory | Off ce rat o exc cGMP 0.0% 100.0% 46.7% Lab Support NSF 2,845 1,120 Office Support NSF 18,962 Office NSF IT NSF 1,522 Con erence | O f ce a o 0% 100% 21% Total RSF 145,192 1.28 Load Factor 9,882 Cafeteria NSF 16

SCALING SUITE: 1 - 5 BAY MODULES

MODULAR PLANNING AND FUTURE FLEXIBILITY

Typical module bays are 10’-6” wide x 36’-0” deep, which work efficiently with 21’-0” structural bays. Partitions for lab, offices, and vivarium will be largely constructed of demountable partition systems except where fire ratings or other considerations make this impractical. Glass panels will be integrated into these systems and will be located along corridors facing into laboratories and offices; this level of transparency is intended to promote collaboration and to bring natural light and views deep into the floorplates.

Lab services will be modular where feasible, and generally provided from overhead service panels in lieu of wall services. Office modules are reduced in size to add common conference spaces into the module.

SCALING SUITE: BALL ROOM STYLE

UNISTRUT DIAGRAM

W G W SH J S - ---0 5005502G U T O R M SF C R 500 50 H S 1 G N- -N O B A T O N S O 80-0008 S S - --------- - - - -- -W O C O O G R M E Q E E O M 9 3 E Q R R O W C R U B N S P C O C W 48 0-0 1- 0 CA NG & NNO SU TE COMPAR SON 750G F T OUTS n u M u en u M d e3 n s g am M N WOM N E EN ppo n O O S H A L W A Y W N OOM E U N S OW R O E R T R 3 L E E E E R E E T R O Y T N T E U A W O O R O M P O P O L W Y O N L B NO E B m W W W C W g W CONF DENT AL AND PROPR ETARY JANUARY 3 2022 As d ca e 4 10-001-00 MARKET NG PLAN - BALL ROOM STYLE 750G F T OUTMARKE NG PL N - SCA NG BA L ROOM S YLE B Y O EN A C UP OR NT ROOM AN EROOM C U POR T S P ORT B Y O EN A T S PPORT T S PP RT TC / SU POR A TE OOM BA O EN AB 5 5 AY O E L B ANT ROOM T SU PO T TC U POR TC SU POR C UP ORT C UP OR 1 B Y O I E P VA E O F E 2 AY OF CE CON PR AT OF C 3 AY OF C CON R V T OF CE 4 AY O CE CON P VA E O F C PR AT OF C CONF DENTIAL AND PROPRIETARY 4810-001-00 750G FIT OUT 11 2 BAY SCAL NG SU TE 1 83 BAY SCAL NG SU TE 13 4 BAY SCAL NG SU TE 1 85 5 BAY SCAL NG SU TE 15 1 BAY SCAL NG OFF CE 1 82 BAY SCAL NG OFF CE = 17 3 BAY SCAL NG OFF CE 1 84 BAY SCAL NG OFF CE m W W W C W g W M N WOM N n O O S H A L W A Y W N OOM E U N S OW R O E R T R 3 E E R E E T R O Y T N T E U A F C O R O M P O P O B O A F C Y O E A F C F A F A W L W N O E L N O E N O N O E L Y O N B A P L 4 B P N B O N B CONF DENT AL AND PROPR ETARY JANUARY 3 2022 As d ca eMARKE NG PL N - SCA NG MODULE 17
e Wa W has az ng Wa LEGEND 1 -6 0 -6 187 SF INNO LAB TC 188 SF INNO LAB 188 SF INNO LAB 187 SF INNO LAB TC S1 10 -6 0 -6 101 81 0 I N N O T C 1 88 N N O L A B 1 53 37 44 1 02 44 2 32 S C A L I N G L A B 1 44 S C A L N G T C CS -A C P- C P-B SP-A SPCS -B CS -A C P- C P-A SP-A SP- CS -A SP- SP-C CS -C DATA OUTLET REFER TO TEL DATA DWG S SERV CE QU CK CONNECTS TYP TW STLOCK ELECTR CAL OUTLETS REFER TO ELEC DWG S CL CL N O M I N A L 20 NOM NA 2 -0 C P-C DATA OUTLET REFER TO TEL DATA DWG S AT SPARE DATA 3 N O M 9 N O M 9 3 E Q 4 3 4 E Q CAP CAP CAP CAP CAP CAP CAP CAP SPARE ELEC 1 V TW T OCK 1 V TW T OC BLANK BLANK 0 W S L K TW ST OCK ELECTR CAL OU LETS REFER TO ELEC DWG S P o N N As nd cated FEBRUARY 11, 2022 1 4 13 Un s u D ag am a on 1 1 2 = 1 -0 6 CSP-C CE L NG SERV CE PANEL e Wa W has az ng Wa LEGEND 1 -6 0 -6 3 -6 187 SF INNO LAB TC 188 SF INNO LAB 188 SF INNO LAB 187 SF INNO LAB TC S1 10 -6 0 -6 101 81 0 N N O T C 1 88 N N O L A B 1 53 37 44 1 02 44 1 -6 2 32 S C A L I N G L A B 1 44 S C A L N G T C CS -A C P- C P-B SP-A SPCS -B CS -A C P- C P-A SP-A SP- CS -A SP- SP-C CS -C DATA OUTLET REFER TO TEL DATA DWG S SERV CE QU CK CONNECTS TYP TW STLOCK ELECTR CAL OUTLETS REFER TO ELEC DWG S CL CL N O M N A L 20 NOM NA 2 -0 C P-C DATA OUTLET REFER TO TEL DATA DWG S AT SPARE DATA 3 N O M 9 N O M 9 3 E Q 4 3 4 E Q CAP CAP CAP CAP CAP CAP CAP CAP SPARE ELEC 1 V TW T OCK 1 V TW T OC BLANK BLANK 0 W S L K TW ST OCK ELECTR CAL OU LETS REFER TO ELEC DWG S P N N As nd cated FEBRUARY 11, 2022 1 4 = 13 Un s u D ag am a on 1 1 2 = 1 -0 6 CSP-C CE L NG SERV CE PANEL Demoun a e Wa W GWB Wa has az ng Wa E s ng Wa LEGEND C u a on Lab - ab Suppo 1 -6 0 -6 3 -6 187 SF INNO LAB TC 188 SF INNO LAB 188 SF INNO LAB 187 SF INNO LAB TC S1 10 -6 0 -6 101 81 0 I N N O T C 1 88 I N O L 13 37 44 12 44 1 -6 22 S C A N G L B 1 44 S L I N T CS -A C P- C P-B SP-A SPCS -B CS -A C P- C P-A SP-A SP- CS -A SP- SP-C CS -C DATA OUTLET REFER TO TEL DATA DWG S SERV CE QU CK CONNECTS TYP TW STLOCK ELECTR CAL OUTLETS REFER TO ELEC DWG S CL CL N O M I N A L 20 NOM NA 2 -0 C P-C DATA OUTLET REFER TO TEL DATA DWG S AT SPARE DATA 3 N O M 9 N O M 9 3 E Q 4 3 / 4 E Q CAP CAP CAP CAP CAP CAP CAP CAP SPARE ELEC 1 V TW T OCK 1 V TW T OC BLANK BLANK 0 W S L K TW ST OCK ELECTR CAL OU LETS REFER TO ELEC DWG S P o N N As nd cated FEBRUARY 11, 2022 1 4 = 13 Un s u D ag am a on 1 1 2 = 1 -0 6 CSP-C CE L NG SERV CE PANEL Demoun a e Wa F G a ng W GWB Wa has C s o G az ng Wa E s ng Wa LEGEND C u a on Lab - ab Suppo 187 SF INNO LAB TC 188 SF INNO LAB 188 SF INNO LAB 187 SF INNO LAB TC S1 11 0 I N N O T C 1 8I N N O L A B 1 53 37 44 1 02 442 S C A N G L A B 1 44 S L I N G T C CS -A C P- C P-B SP-A SPCS -B CS -A C P- C P-A SP-A SP- CS -A SP- SP-C CS -C DATA OUTLET REFER TO TEL DATA DWG S SERV CE QU CK CONNECTS TYP TW STLOCK ELECTR CAL OUTLETS REFER TO ELEC DWG S CL CL O M I N A L 20 NOM NA 2 -0 C P-C DATA OUTLET REFER TO TEL DATA DWG S AT SPARE DATA 3 N O M 9 N O M 9 3 E Q 4 3 / 4 E Q CAP CAP CAP CAP CAP CAP CAP CAP SPARE ELEC 1 V TW T OCK 1 V TW T OC BLANK BLANK 0 W S L K TW ST OCK ELECTR CAL OU LETS REFER TO ELEC DWG S P o N N As nd cated FEBRUARY 11, 2022 1 4 = 13 Un s u D ag am a on 1 1 2 = 1 -0 6 CSP-C CE L NG SERV CE PANEL Demoun a e Wa F G a ng W GWB Wa P mb g Chas C s o G az ng Wa E s ng Wa LEGEND C u a on Lab - ab Suppo 187 SF INNO LAB TC 188 SF INNO LAB 188 SF INNO LAB 187 SF INNO LAB TC S1 1 81 I N N O T C8 N N O L A B 1 57 41 02 44 2 32 S C L I N G L A B 1S C A L N T C CS -A C P- C P-B SP-A SPCS -B CS -A C P- C P-A SP-A SP- CS -A SP- SP-C CS -C DATA OUTLET REFER TO TEL DATA DWG S SERV CE QU CK CONNECTS TYP TW STLOCK ELECTR CAL OUTLETS REFER TO ELEC DWG S CL CL N M N A 2NOM NA 2 -0 C P-C DATA OUTLET REFER TO TEL DATA DWG S AT SPARE DATA N M 9 N O M 9 3 E Q 4 3 4 E Q CAP CAP CAP CAP CAP CAP CAP CAP SPARE ELEC 1 V TW T OCK 1 V TW T OC BLANK BLANK 0 W S L K TW ST OCK ELECTR CAL OU LETS REFER TO ELEC DWG S N N As nd cated FEBRUARY 11, 2022 1 4 13 Un u D Un u oca on 1 1 2 1 -0 6 CSP-C CE L NG SERV CE PANEL Legend Lab Lab Support Existing Wall GWB Wall Demountable Wall Plumb Chase Unistrut
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Simcere Innovation, Inc.
Cell & Gene Therapy Innovation Center

LABORATORY AS A SHOWCASE

The Simcere Innovation Center for Cell & Gene Therapies includes laboratories, office areas, and meeting spaces for 150 scientists, administrators, and executives collaborating to advance novel therapies for treating human disease. Laboratory areas are designed to showcase biotech innovation and include glass walls for views into the highly flexible open lab and instrument rooms. Laboratory areas also follow modular planning principles – from the standardization of lab services to the selection of mobile benches – to allow rapid change in layouts and instruments.

Legend

Building Core Office

Write-up Office

Research Lab

Research Lab Support

SIMCERE OF AMERICA

WOVEN CONNECTIONS OF BRAND AND CULTURE

Office areas, café, and meeting spaces are an extension of the lab environment, all of which reflect the Simcere brand in finishes and color palette. Natural light and access to views are available throughout, adding to the visual appeal of the laboratories and workplace.

3.5 Previous Plan Option 2 CAMBRIDGE DISCOVERY PARK Level 2 May 2019 SIMCERE INNOVATION 16' 32' LEGEND BUILDING CORE OFFICE RESEARCH LAB RESEARCH LAB SUPPORT WRITE-UP OFFICE
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University Hall

University of Massachusetts, Boston

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ACADEMIC ARK

University Hall’s rare combination of arts and sciences programs, along with 26 state-of-the-art, general-purpose classrooms, will redefine the academic experience at UMass Boston. Blurring the boundaries between disciplines, the new program is ideally suited for STEAM learning.

Performing Arts

Art

Classrooms

Chemistry

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Level 1 Level 2 Level 3 Level 4

predicted energy use reduction

per year, predicted energy use intensity water use reduction

54% 105 kBTU/sf
22 4 3 1 2
LEED Gold 40% Legend 1. Atrium 2. Studio Theatre 3. Recital Hall 4. Penthouse

OWNERSHIP OF SPACE

The copper wall wrapping the auditorium and forming the edge of the monumental stair, became a student signature wall, allowing users to ‘leave their mark’ and have a sense of ownership of the space and belonging to the community.

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Brooks Building

IYRS School of Technology & Trades

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LEARNING AT THE WORKING WATERFRONT

The campus of the international Yacht Restoration School (IYRS) is sited within a working waterfront business district in downtown Newport, fronting historic Thames Street. This setting is ideal for hands-on education in boat restoration and related technologies.

Elevated Massing

RESILIENCE

Traffic and Parking

Resilient Parking Design to Accommodate Flooding

Newport, located in the FEMA VE flood zone, has seen severe flooding, most recently with Superstorm Sandy in 2012. The existing IYRS campus buildings—durable masonry structures dating from the 18th and 19th centuries—withstood the storm, though interiors and equipment areas flooded knee-deep throughout. The Brooks Building sits adjacent to these historic buildings, its design embracing the substantial challenges of resiliency required of this setting.

Resilient Parking Design to Accommodate Flooding NEW BUILDING

RESILIENCE

Resilient Parking Design to Accommodate Flooding Traffic and Parking
Newport, located in the FEMA VE flood zone, has seen severe flooding, most recently with Superstorm Sandy in 2012. The existing IYRS campus buildings—durable masonry structures dating from the 18th and 19th centuries—withstood the storm, though interiors and equipment areas flooded knee-deep throughout. The Brooks Building sits adjacent to these historic 25
Resilient Parking Design to Accommodate Flooding

ADVANCED COMPOSITES

The program for the building includes two floors—20,000 SF—of classroom and trade teaching areas for Composites Technology, Marine Systems, and Digital Modeling & Fabrication programs. Much of the program in this new space will be technology-based and related to the use of modern materials and components such as carbon fiber, composites, and CAD fabricated assemblies.

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IYRS School of TechnologY & TRadeS / 7500-00 hoist Study / 22 december 2016

FLEXIBLE FURNITURE CONFIGURATIONS

27 Merck Research Laboratories Renovation Merck & Co., Inc.
Merck MrL c aMbridge Level 4 renovations august 2016 OPeN cOLLabOraT Ve SPace Lounge Table: Martin bratrud Table Lounge chair: Steelcase Side Walk chair existing Lounge Seating NeW LOUNge cHairS eX ST Ng LOUNge SeaT Ng accent Paint: beNJaM N MOOre NeW LOUNge TabLe glass Markerboard: cLarUS Fabrics (Placeholder): deSigNTeX Lounge chair alternate: global, ballara eX ST Ng WOrkSTaT ON recONFigUred W TH TraNSacT ON TOP DRAFT FURNITURE AND FINISHES CONCEPT Merck MrL c aMbridge Level 4 renovations September 2016 cHeM STrY Lab glass Markerboard accent Paint: SHerW N W LLiaMS color: SW6802 Jacaranda Wall Paint: SHerW N W LLiaMS color: SW6251 Outerspace TYP. Wall Paint: SHerW N W LLiaMS color: SW7006 extra White Flooring: arMSTrONg STriaT ONS bbT 12”x24” color: T3602 Steel DRAFT DRAFT FURNITURE AND FINISHES CONCEPT 28 FURNITURE AND FINISHES

CATWALK STRATEGY

The cGMP Upgrade program has been established to bring the existing facilities around the globe up to the current GSOP 268-4 GMP facility standard, which includes upgrade of the existing production facility main circulation corridor to a GMP Class F1 Clean Corridor.

To achieve this, new mezzanine level access catwalks are created, to provide maintenance access to equipment rooms, which are unclassified, from unclassified spaces – thus avoiding the requirement for airlocks and gowning facilities.

Legend

1. New Epoxy Floor w/ Wall Cove

2. New Stainless Steel Floor Mounted Bumper Rail

3. Existing CMU Wall

4. Existing Bar Joist Support for Platform

5. Existing Steel Column

6. Existing Guardrail

7. New Ship’s Ladder

8. Existing Bar Joist

9. New Roof Hatch

10. New Continuous Trapeze for Piping

Confidential cGMP Upgrade

Multiple Sites

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1 2 3 4 5 6 7 8 9 10
EXISTING EQUIPMENT PLATFORM EXISTING EQUIPMENT PLATFORM NEW CATWALK CONNECTING PLATFORMS Legend Exist Equip Platform New Access Catwalk New Access Stair New Roof Hatch

TYPICAL PAL/ MAL (PERSONNEL AIRLOCK/MATERIAL AIRLOCK)

Personnel airlocks are specialized airlocks for the entry and exit of personnel to and from clean rooms. Personnel airlocks provide physical separation (step over bench, clearly indicated demarcation line) between the different zones in order to maintain the integrity of the cleanroom into which it leads, particularly with regard to the control of microbial and particulate contamination shed from personnel and protective clothing.

Material airlocks are specialized airlocks required for the transfer of materials such as starting and raw materials, components, reagents, solvents, intermediates, packaging and labelling materials, containers, drums, etc. into any cleanliness class beginning with F1.

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D - C PERSONNEL & MATERIAL AIRLOCKS
Owner Wilson HGA 374 Congress Street 617.338.5990 617.338.5991 Architect Broad Institute MIT Harvard 75 Ames Street Cambridge, MA 02142 617.714.7000 MEP Engineer BR+A 10 Guest Street 617.254.7423 617.924.9339 Consultants Broad Project FY2020 Wilson HGA Project #: 4474-002-00 JENSEN HUGHES 1661 Worcester Road, Suite 501 Framingham, MA 01701 508.620.8900 75 Ames Street -8th Floor Reorganization 20 April 2020 (REVISED -22 July 2020) Construction Documents H1.08 H2.08 E2.08A E2.08B 6-Technology T2.08 T5.01 1-Architectural A1.08 LEVEL DEMOLITION PLAN A9.11 FINISH SCHEDULE A10.01 CASEWORK MENU 3-Plumbing P0.01 PLUMBING DETAILS PD1.08 PLUMBING LEVEL DEMOLITION SUPPLY PLAN Concept BUILDING ON THE CHARACTER OF SOMERVILLE VIEW FROM NORTH EAST 31 Other Projects 4-309 Renovation Merck & Co., Inc. Optical Platform Broad Institute of MIT and Harvard Project Beacon Broad Institute of MIT and Harvard 3rd Floor Renovation Merck & Co., Inc. Longwood Refresh Merck & Co., Inc. LAR Surgery Suite Merck & Co., Inc. Building X University of Delaware Reagent CFDA Compliance BD Biosciences 8th & 9th Floor Reorganization Broad Institute of MIT and Harvard Level M1 Fitout Broad Institute of MIT and Harvard Regev Laboratory Space Evaluation Study Broad Institute of MIT and Harvard Interdisciplinary Science and Engineering Building Case Western Reserve University Biocytogen Fitout Biocytogen Boston Corporation Kaiser Permanente Regional Genetics Laboratory Kaiser Foundation Health Plan, Inc. Kaiser Richmond Regional Lab Decompression Project Kaiser Foundation Health Plan, Inc. Center for Engineering and Computer Science Dartmouth College Huntington Avenue Study M.H. Massey & Co. Avison Young Kresge Building Project (Competition) Harvard T. H. Chan School of Public Health Biotech 1 - Liberty/ Welgen Renovations Umass Medical School Boynton Yards (Competition) DLJ Leggat McCall

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