1-(Benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one, CAS 52190–28–0, is a brominated derivative of benzaldehyde and a key intermediate in organic synthesis. It is a colorless to yellow liquid with a molecular formula of C10H9BrO3 and a molecular weight of 245.082. 1-(Benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one is soluble in organic solvents and has good stability under ambient conditions.
1-(Benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one is mainly used for the preparation of various derivatives and analogs, such as 1-(benzo[d][1,3]dioxol-5-yl)-2-amino propane, 1-(benzo[d][1,3]dioxol-5-yl)-2-(N-morpholino) propane and 1-(benzo[d][1,3]dioxol-5-yl)-2-(N-piperidino) propane. These derivatives have extensive applications in the fields of medicine, pesticides, and materials science. For example, some derivatives can be used as inhibitors of histone deacetylase (HDAC), which can be used for the treatment of various cancers.
