Alerta de revistas, libros y material electrónico en salud (agosto-octubre2022). Acércate al personal bibliotecario Centro de Documentación en SaludBiblioteca, HGZ 1A.
Michael W. Holliday Jr., Qingtian Li, Edlyn G. Bustamante, Jingbo Niu, Luping Huang, Ilse M. Espina, Jose R. Dominguez, Luan Truong, Kristy O. Murray, Lei Fan, Samaya J. Anumudu, Maulin Shah, Rebecca S.B. Fischer, Chandan Vangala, Sreedhar Mandayam, Jose Perez, Jenny S. Pan, Sehrish Ali, Ahmed A. Awan, and David Sheikh-Hamad
Editorials
See related article and Perspectives on pages 1372, 1403, and 1407, respectively.
1269 Unraveling the Mysteries of CKD of Uncertain Etiology
See related article on page 1337.
See related article on page 1363.
Sumit Mohan and S. Ali Husain
See related editorial on page 1281.
Clinical Nephrology
Dinushika Mohottige and Delphine S. Tuot
Michael “Jack” Lennon
See related article on page 1293.
See related article on page 1305.
1281 Advancing Kidney Health Equity: Influences of Gender-Affirming Hormone Therapy on Kidney Function
Pablo Garcia and Shuchi Anand
Hannah Melchinger, Frida Calderon-Gutierrez, Wassim Obeid, Leyuan Xu, Melissa M. Shaw, Randy L. Luciano, Michael Kuperman, Gilbert W. Moeckel, Michael Kashgarian, F. Perry Wilson, Chirag R. Parikh, and Dennis G. Moledina
1272 Transplant Nephrology
September 2022 ● Vol. 17 ● No 9
See related editorial on page 1269.
1305 The Effect of Gender-Affirming Hormone Therapy on Measures of Kidney Function: A Systematic Review and Meta-Analysis Emily Krupka, Sarah Curtis, Thomas Ferguson, Reid Whitlock, Nicole Askin, Adam C. Millar, Marshall Dahl, Raymond Fung, Sofia B. Ahmed, Navdeep Tangri, Michael Walsh, and David Collister
1284 Urine Uromodulin as a Biomarker of Kidney Tubulointerstitial Fibrosis
Michel Chonchol, Orlando M. Gutierrez, Mahboob Rahman, David M. Charytan, and Mitchell Rosner
1278 Improving the Utilization of Deceased Donor Kidneys by Prioritizing Patient Preferences
Chronic Kidney Disease
See related article on page 1363.
Original Articles
1275 Mitigating Pain in People Undergoing Hemodialysis
1293 Potential Mechanisms Involved in Chronic Kidney Disease of Unclear Etiology
Sara N. Davison
Patient Voice
1267 Getting a Kidney: Where Is Patient Choice?
Transplantation
1316 Automated Prediction of Kidney Failure in IgA Nephropathy with Deep Learning from Biopsy Images Francesca Testa, Francesco Fontana, Federico Pollastri, Johanna Chester, Marco Leonelli, Francesco Giaroni, Fabio Gualtieri, Federico Bolelli, Elena Mancini, Maurizio Nordio, Paolo Sacco, Giulia Ligabue, Silvia Giovanella, Maria Ferri, Gaetano Alfano, Loreto Gesualdo, Simonetta Cimino, Gabriele Donati, Costantino Grana, and Riccardo Magistroni
Glomerular and Tubulointerstitial Diseases
Critical Care Nephrology and Acute Kidney Injury
1399 Choosing the Right Treatment in Patients with Lupus Nephritis
Perspectives
See related Patient Voice and editorial on pages 1267 and 1278, respectively.
1403 The Importance of Transplant Nephrology to a Successful Kidney Transplant Program Sharon M. Moe, Daniel C. Brennan, Mona D. Doshi, Robert S. Gaston, Susan B. Gurley, Muhammad A. Mujtaba, Rebecca J. Schmidt, Mark S. Segal, J. Kevin Tucker, Alexander C. Wiseman, and Michelle A. Josephson
1337 Effect of Music in Reducing Pain during Hemodialysis Access Cannulation: A Crossover Randomized Controlled Trial Emi Inayama, Yosuke Yamada, Masatsugu Kishida, Mineaki Kitamura, Tomoya Nishino, Keiko Ota, Kanae Takahashi, Ayumi Shintani, and Tatsuyoshi Ikenoue
Kidney Case Conference: How I Treat
1372 Survey of Salary and Job Satisfaction of Transplant Nephrologists in the United States Neeraj Singh, Mona D. Doshi, Jesse D. Schold, Luke Preczewski, Christina Klein, Enver Akalin, Nicolae Leca, Kimberly Nicoll, Todd Pesavento, Darshana M. Dadhania, John Friedewald, Milagros Samaniego-Picota, Roy D. Bloom, and Alexander C. Wiseman
Maintenance Dialysis
See related articles on pages 1272, 1372, and 1407, respectively.
See related articles on pages 1272, 1372, and 1403, respectively.
1407 Existing Transplant Nephrology Compensation Models and Opportunities for Equitable Pay Michelle A. Josephson, Alexander C. Wiseman, J. Kevin Tucker, Mark S. Segal, Rebecca J. Schmidt, Muhammad A. Mujtaba, Susan B. Gurley, Robert S. Gaston, Mona D. Doshi, Daniel C. Brennan, and Sharon M. Moe
1346 Incidence and Risk Factors for Dialysis Reinitiation among Patients with a History of Dialysis Dependency Elaine Ku, Raymond K. Hsu, Charles E. McCulloch, Lowell Lo, Timothy Copeland, Salpi Siyahian, Barbara Grimes, and Kirsten L. Johansen
1325 Three Times Weekly Dosing of Daprodustat versus Conventional Epoetin for Treatment of Anemia in Hemodialysis Patients: ASCEND-TD: A Phase 3 Randomized, Double-Blind, Noninferiority Trial
1363 Patient Preferences for Waiting Time and Kidney Quality
Sanjay Mehrotra, Juan Marcos Gonzalez, Karolina Schantz, Jui-Chen Yang, John J. Friedewald, and Richard Knight
1382 Central Venous Catheter Malfunction in Children: A Bioengineering Approach Claudia Bruno, Rayan Moumneh, Emilie Sauvage, Lynsey Stronach, Kathryn Waters, Ian Simcock, Owen Arthurs, Silvia Schievano, Claudio Capelli, and Rukshana Shroff
Research Letter
Daniel W. Coyne, Ajay K. Singh, Renato D. Lopes, Christine K. Bailey, Tara L. DiMino, Chun Huang, Jeffrey Connaire, Anjay Rastogi, Sung-Gyun Kim, Marcelo Orias, Sapna Shah, Vickas Patel, Alexander R. Cobitz, and Christoph Wanner
Juan Manuel Mejia Vilet, Zhi-Hong Liu, and Tak Mao Chan
1353 Implications of Accumulated Cold Time for US Kidney Transplantation Offer Acceptance Masoud Barah, Vikram Kilambi, John J. Friedewald, and Sanjay Mehrotra
1385 Acute Kidney Injury in Critically Ill Patients with Cancer Shruti Gupta, Prakash Gudsoorkar, and Kenar D. Jhaveri
See related editorial and Perspectives on pages 1272, 1403, and 1407, respectively.
See related editorial on page 1275.
Niloofar Nobakht, Mohammad Kamgar, Robert M. Bilder, and Ehsan Nobakht
1410 Music for Health: From Ear to Kidney
Clodagh Cogley, Claire Carswell, Kate Bramham, and Joseph Chilcot
14 18 Extracellular Vesicles as Theranostic Tools in Kidney Disease
A 50-year-old male presented with loss of appetite, dyspnea, and AKI following coronavirus 2019 (COVID-19) infection 3 months ago. The AKI required hemodialysis support. Other medications at the time of presentation included erythromycin 500 mg/day, an oral corticosteroid, and telmisartan 20 mg daily for hypertension. Fundus examination was unremarkable. Routine urine analysis showed 1+ protein and no cellular elements. Urine protein-creatinine ratio and serum creatinine were 0.6 g/g and 7.8 mg/dL, respectively. Earlier records documented normal kidney function 1 year ago. Of note, it was discovered that the patient was taking a vitamin C supplement 1 g/day that was initiated during COVID-19 illness and continued for 3 months. Biopsy was performed in view of nonrecovery of kidney function at 3 KidneyImagemonths.Description:biopsyrevealed
What is the diagnosis?
On the Cover
Teaching Points: AKI in patients infected with COVID-19 may be associated with multifactorial etiologies such as sepsis, hypoperfusion, cytokine storm, possible direct cytopathic effect of the virus, thrombotic microangiopathy, pigment nephropathy, and therapeutic complications. Kidney complications may also be secondary to antibiotics and vitamin C supplements. The unproven rationale for supplementing vitamin C in COVID-19 is to prevent sepsis-induced cytokine production and reduce proin flammatory biomarkers and disease-related mortality. However, endogenous conversion of ascorbic acid to oxalate causes hyperoxaluria. Fontana et al. have reported two cases of intravenous vitamin C supplementation induced oxalate nephropathy with dosage of 50 mg/kg four times per day in patients with COVID-19 infection (1). We believe that continued overdosage of vitamin C led to formation of oxalate crystals. Less than half of patients with oxalate nephropathy require KRT and remain dialysis dependent. Our patient remained dialysis dependent at the end of 4 weeks despite withdrawal of vitamin C following biopsy findings. We attribute nonrecovery to the interstitial fibrosis noted on the histology and hence progressing to CKD. Clinicians should keep occurrence of oxalate nephropathy with vitamin C supplementation among the differentials of AKI in COVID-19
1.Reference:patients.Fontana F, Cazzato S, Giovanella S, Ballestri M, Leonelli M, Mori G, Alfano G, Ligabue G, Magistroni R, Cenacchi G, Antoniotti R, Bonucchi D, Cappelli G: Oxalate nephropathy caused by excessive vitamin C administration in 2 patients with COVID-19. Kidney Int Rep 5: 1815 1822, 2020.
diffuse acute tubular injury with attenuated epithelium lining. Most of the tubules showed fan-shaped transparent crystals arranged radially within tubular lumens distorting luminal contours. Crystals are birefringent under polarizer. Mild degree of interstitial fibrosis is noted. Glomerular and vascular compartments showed nonspecific findings. Immunofluorescence was negative with entire panel (IgG/A/M, C3/C1q, Kappa/Lambda) of antisera.
(Image and text provided by Mahesha Vankalakunti, Manipal Hospital, Bengaluru, India; Kiran K. Gowda, Manipal Hospital, Bengaluru, India; and Madhusudan H. Channegowda, Mangala Hospital, Hassan, India)
14 13 Chronic Kidney Disease and Severe Mental Illness: Addressing Disparities in Access to Health Care and Health Outcomes
Weijun Huang, Xiang-Yang Zhu, Amir Lerman, and Lilach O. Lerman
Reviews
413 Pharmacokinetics of Intravenously (DIZ101), Subcutaneously (DIZ102), and Intestinally (LCIG) Infused Levodopa in Advanced Parkinson Disease
A. Lleo and I. Ill an-Gala
OPEN ACCESS CME Course Class of Evidence
Full articles at Neurology.org/N
T.R. Meinel, C. Lerch, U. Fischer, M. Beyeler, A. Mujanovic, C. Kurmann, B. Siepen, A. Scutelnic, M. Mu ller, M. Goeldlin, N.F. Belachew, T. Dobrocky, J. Gralla, D. Seiffge, S. Jung, M. Arnold, R. Wiest, R. Meier, and J. Kaesmacher OPEN ACCESS
Chord diagrams representing connections between neuropathologic lesions and final cognitive diagnosis of patients enrolled in The 90+ Study. Stylized by Kaitlyn Aman Ramm, Digital Multimedia/Graphics Coordinator.
415 Long-term Efficacy and Safety From an Open-Label Extension of Adjunctive Cenobamate in Patients With Uncontrolled Focal Seizures
P. Klein, S. Aboumatar, C. Brandt, F. Dong, G.L. Krauss, S. Mizne, J.C S anchez-A´lvarez, B.J. Steinhoff, and V. Villanueva
L. Wang, P. Wu, P. Brown, W. Zhang, F. Liu, Y. Han, C.-T. Zuo, W. Cheng, and J. Feng
Editorials
419 Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia
OPEN ACCESS Editorial, p. 361
Cover Image
409 Early Motor Changes in Genetic Frontotemporal Dementia
NPub.org/aheadofprint Continued
OPEN ACCESS Class of Evidence Podcast
H. Li, S. Li, H. Yang, Y. Zhang, S. Zhang, Y. Ma, Y. Hou, X. Zhang, K. Niu, Y. Born e, and Y. Wang Editorial, p. 411
417 Multivariable Prediction Model for Futile Recanalization Therapies in Patients With Acute Ischemic Stroke
F. Bergquist, M. Ehrnebo, D. Nyholm, A. Johansson, F. Lundin, P. Odin, P. Svenningsson, F. Hansson, L. Bring, E. Eriksson, and N. OPENDizdarACCESS
Neurology.org/N
P van der Meer, L Dirven, M Fiocco, M J Vos, M C M Kouwenhoven, M J van den Bent, M J B Taphoorn, and J.A.F Koekkoek
406 This Week’ s Neurology® Podcast
Volume 99, Number 10, September 6, 2022
416 Effectiveness of Antiseizure Medication Duotherapies in Patients With Glioma: A Multicenter Observational Cohort Study
See page 422
S. Scho necker, F.J. Martinez Murcia, B. S. Rauchmann, N. Franzmeier, C. Prix, E Wlasich, S V Loosli, K. Bochmann, J M Gorriz Saez, R. Laforce, Jr., S. Ducharme, M.C. Tartaglia, E. Finger, A. de Mendonça, I. Santana, R. Sanchez-Valle, F. Moreno, S. Sorbi, F. Tagliavini, B. Borroni, M. Otto, M. Synofzik, D. Galimberti, R. Vandenberghe, J. van Swieten, C. Butler, A. Gerhard, C. Graff, A. Danek, J.D. Rohrer, M. Masellis, J. Rowe, and J. Levin, on behalf of The Genetic Frontotemporal Dementia Intiative (GENFI)
420 Longitudinal Effects of Combination Antiretroviral Therapy on Cognition and Neuroimaging Biomarkers in Treatment-Naive People With HIV
A.B. Giritharan and T.L. Davis
418 Trajectory Pattern of Cognitive Decline in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
S. Brice, S. Reyes, A. Jabouley, C. Machado, C. Rogan, N. Gastellier, N. Alili, S. Guey, E. Jouvent, D. Herv´e, S. Tezenas du Montcel, and H. OPENChabriatACCESS
TABLE OF CONTENTS
407 Will Subcutaneous Levodopa Stick? Old Dog, New Trick
421 Association of Ultraprocessed Food Consumption With Risk of Dementia: A Prospective Cohort Study
405 Spotlight on the September 6 Issue
411 Identifying Ultraprocessed Foods in Nutrition Research: What a Process! M.E. Walker and N.L. Spartano
Editorial, p. 407
M.T. Weber, A. Finkelstein, M.N. Uddin, E.A. Reddy, R.C. Arduino, L. Wang, M.E. Tivarus, J. Zhong, X. Qiu, and G. Schifitto
In Focus
Ahead of Print Articles and Editorials
414 Association of Structural Measurements of Brain Reserve With Motor Progression in Patients With Parkinson Disease
Research Articles: Short Format
Copyright
© 2022 American Academy of Neurology. Unauthorized reproduction of this article is prohibited.
424 Views on Memory and Treatment of Cognitive Impairment in 17th Century Spain: Juan Gutie´rrez de Godoy’ s Work
K.K.F. Loo Yong Kee, W. Jan, and C.J. Carswell
447 Reader Response: Teaching NeuroImage: Leber Hereditary Optic Neuropathy With Longitudinal Spinal Cord Lesion Mimicking Spinal Cord Infarction
430 Journal Club: Criteria for Defining Interictal Epileptiform Discharges in EEG
433 Pearls & Oy sters: Reversible Postpartum Pseudocoma State Associated With Magnesium Therapy: A Report of 2 Cases
Historical Neurology
448 Author Response: Teaching NeuroImage: Leber Hereditary Optic Neuropathy With Longitudinal Spinal Cord Lesion Mimicking Spinal Cord Infarction
In the Next Issue of Neurology®
Department
446 Author Response: Lack of Association of Group A Streptococcal Infections and Onset of Tics: European Multicenter Tics in Children Study
B. Zhao, Y. Sun, Y. Zhang, and C. Yan
442 Teaching NeuroImage: Crowned Dens Syndrome: An Acute Attack of Calcium Pyrophosphate Deposition Disease Mimicking Acute Meningitis
J.-A. Palma and F. Palma
A. Francia, G. Conte, G. Platania, A. Arighi, A.M. Pietroboni, G.G. Fumagalli, S. Floro, E. Scarpini, D. Galimberti, M.C. Saetti, and T. Carandini
428 Giant Tumefactive Perivascular Spaces in a Patient Presenting With a First Seizure
T. Friedman-Korn, Y. Lerner, S. Haggiag, A. Nama, D. Ekstein, Z. Argov, A. Vaknin-Dembinsky, and M. Gotkine
445 Reader Response: Lack of Association of Group A Streptococcal Infections and Onset of Tics: European Multicenter Tics in Children Study
R. Gupta, D. Agalliu, A. Spalice, H.M. Lachman, T. Ubhi, K. Chang, J. Frankovich, A. Fasth, M. Johnson, E. Fernell, I. Walles, S. Bejerot, P.J. van der Spek, and J.L. Cunningham
M. Regensburger, I.T. Spatz, M. Ollenschl ager, C.F. Martindale, P. Lindeburg, Z. Kohl, B. Eskofier, J. Klucken, R. Schu le, S. Klebe, J. Winkler, and H. Gaßner
J.R. McLaren, J. Jing, M.B. Westover, and F.A. Nascimento
Disputes & Debates: Editors’ Choice
J.E. Siegler and S. Galetta
J.E. Siegler and S. Galetta
TABLE OF CONTENTS
A. Schrag
Resident & Fellow Section
445 Editors’ Note: Lack of Association of Group A Streptococcal Infections and Onset of Tics: European Multicenter Tics in Children Study
N.K. Irani, K.D. O’Connor, and J.H. Lock
Volume 99, Number 10, September 6, 2022 Neurology.org/N
447 Editors’ Note: Teaching NeuroImage: Leber Hereditary Optic Neuropathy With Longitudinal Spinal Cord Lesion Mimicking Spinal Cord Infarction
422 Association of Cognition and Dementia With Neuropathologic Changes of Alzheimer Disease and Other Conditions in the Oldest Old T.J. Montine, M.M. Corrada, C. Kawas, S.A. Bukhari, L.R. White, L. Tian, and B. Cholerton CME Course
NeuroImages
423 Inertial Gait Sensors to Measure Mobility and Functioning in Hereditary Spastic Paraplegia: A Cross-sectional Multicenter Clinical Study
437 Pearls & Oy-sters: Two Cases of Stereotactic EEG-Proven Insular Epilepsy With Nonlocalizing Scalp EEG and Interesting Semiologies
D. Li, I. Podkorytova, M. Dieppa, and G. Perven
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Life Expectancy for White, Black, and Hispanic Race/Ethnicity in U.S. States: Trends and 1057
One of the ways Medicare has supported U.S. primary care practice is by introducing new codes for prevention and coordination services into the Medicare Physician Fee Schedule.
Benign neutropenia related to an ACKR1 variant (rs2814778-CC) is common among persons of African ancestries. In this study, the authors assessed whether 1092
S.D. Agarwal, S. Basu, and B.E. Landon
August 2022 ● Volume 175 ● Number 8 ● Pages 1057-1200
Quantifying Individual-Level Inaccuracy in Glomerular Filtration Rate Estimation
Effect of Social Needs Case Management on Hospital Use Among Adult Medicaid Beneficiaries
Annals of Internal Medicine
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A.L. Dickson, L.L. Daniel, E. Jackson, J. Zanussi, W. Yang, W.D. Plummer, W.D. Dupont, W.Q. Wei, P. Nepal, A.M. N.J.Hung,Cox, S.L. Van Driest, Q. Feng, J.J. Yang, C.M. Stein, J.D. Mosley, and C.P. Chung
who inject drugs (PWID) threatens HCV elimination and
Contents
da,CepeJ.A.
1109
exacerbates social and racial health disparities. This community-based, longitudinal cohort study assessed whether all-oral HCV treatments were accessed by PWID and reduced liver disease burden and mortality.
Original Research
Population-level differences between estimated and measured glomerular filtration rates (eGFRs and mGFRs) are
addition, anticoagulation was prescribed to only 19.6% of patients that developed postoperative AF. These findings have important clinical, safety, and policy implications for the care and management of AF in the perioperative period.
W
Brown and colleagues evaluated a large-scale, randomized case management program aimed at addressing medical and social needs among Medicaid recipients in Contra Costa County, California. Individuals randomly assigned to case
In this retrospective cohort study, the risk for stroke or tran- sient ischemic attack at 5 years was similar among patients with incident postoperative atrial fibrillation (AF) as com- pared with patients with AF in a nonoperative setting. In
D.L. Thomas, J. Astemborski, J.E. Rudolph, R. Gicquelais, G.D. Kirk, and S.H. Mehta
rs2814778-CC was associated with azathioprine discontinuation attributed to hematopoietic toxicity and lower thiopurine dosing, independent of race and across indications.
Comparing Racial Differences in Emphysema 1118
After decades of gradual improvements, life expectancy is no longer increasing in the United States. This national
Race, Genotype, and Azathioprine Discontinuation
K.C. Siontis, B.J. Gersh, S.A. Weston, R. Jiang, V.L. P.A.Roger,Noseworthy, and A.M. Chamberlain 1065
T. Shafi, X. Zhu, S.T. Lirette, A.D. Rule, T. Mosley, K.R. Butler,
D.M. Brown, E.A. Hernandez, S. Levin, M. De Vaan, M.O. C.Kim,Lynch, A. Roth, and A.L. Brewster
M.E. Hall, P. Vaitla, J.J. Wynn, M.C. Tio, N.R. Dossabhoy, E. Guallar, and J. Butler
Disparities, 1990 to 2019
management had 11% fewer total hospitalizations and 4% fewer emergency department visits. The program shows the promise of this type of approach, although uptake and costs of the program may remain barriers to diffusion. well recognized. This study quantifies the magnitude of less well-known individual-level differences between mGFRs and eGFRs and examines the clinical implications.
Prevalence Among Adults With Normal Spirometry:
Impact of Hepatitis C Treatment Uptake on Cirrhosis and Mortality in Persons Who Inject Drugs
across states from 1990 to 2019 to examine trends for each group over time and how they differ.
trend masks disparities among states and between racial and ethnic groups. Authors estimated life expectancy sepa- rately by sex for each of the 3 largest race/ethnicity groups
C.O. Johnson, A.S. Boon-Dooley, N.K. DeCleene, K.F. Henny, B.F. Blacker, J.A. Anderson, A. Afshin, A. Aravkin, M.W. Cunningham, J.L. Dieleman, R.G. Feldman, E. Gakidou, A.H. Mokdad, M. Naghavi, C.N. Spencer, J.L. Whisnant, H.W. R.R.York,Zende, P. Zheng, C.J.L. Murray, and G.A. Roth
The study reported in this article measured how often physicians use the new codes and estimated how much revenue they forgo when they do not use the codes. The authors con- clude that adding more codes may not be an effective policy.
The Underuse of Medicare’s Prevention and Coordination Codes in Primary Care 1100 Associations of Atrial Fibrillation After Noncardiac Surgery With Stroke, Subsequent Arrhythmia, and Death
Continued on page I-12
G.Y. Liu, S.S. Khan, L.A. Colangelo, D. Meza, G.R. Washko, P.H.S. D.R.Sporn,Jacobs, M.T. Dransfield, M.R. Carnethon, and R. Kalhan
sis of the CARDIA Lung Study
Postmaster: Send changes of address to Customer Service, Annals of Internal Medicine, 190 N. Independence Mall West, Philadelphia, PA 19106-1572. ● Annals of Internal Medicine is published monthly and copyrighted © 2022 by the American College of Physicians, 190 N. Independence Mall West, Philadelphia, PA 19106-1572. Basic member subscription price is $42.00 per year. Periodicals postage paid at Philadelphia, Pennsylvania, and at additional mailing offices. Canadian Publications Mail Agreement #40030513. (ACP/Brokers, 1031 Helena Street, Fort Erie, Ontario L2A 5N8, Canada.) GST ID#128512159. ● AIMEAS 175(8)1057-1200(2022) ● Print ISSN 0003-4819 ● Online ISSN 1539-3704
In this secondary data analysis of 2674 participants from the CARDIA study, 6.5% of patients with 80% to 99% of The World Health Organization has called for the elimination of hepatitis C virus (HCV) infection by 2030. However, historically low uptake of HCV treatment among people
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AnalyDatandarySecoA
predicted race-specific FEV1 had radiographic evidence of emphysema. Black men and women had almost 4-fold 2-foldand greater prevalence of emphysema than White men
Position Papers
CME/MOC activity available at Annals.org
Long-Term Services and Supports for Older Adults
Patients and physicians are interested in alternative treatments for chronic pain. Cannabis derivatives, or cannabinoids, including tetrahydrocannabinol (THC) and cannabidiol (CBD), may have analgesic properties. The authors examined the effectiveness and harms of different cannabis products according to the ratio of THC to CBD.
M.G. Johnson, A. Puenpatom, P.A. Moncada, L. Burgess, E.R. Duke, N. Ohmagari, T. Wolf, M. Bassetti, S. Bhagani, J. Ghosn, Y. Zhang, H. Wan, A. Williams-Diaz, M.L. Brown, A. Paschke, and C. De Anda In the MOVe-OUT trial, molnupiravir showed a clinically meaningful reduction in the risk for hospitalization or indeathadults with mild to moderate COVID-19 and risk factors for progression to severe disease. This secondary analysis of the trial sought to identify other potential clinical bene- fits of molnupiravir versus placebo.
Cannabis-Based Products for Chronic Pain 1143
Summary for Patients I-28
How Would You Treat This Patient With Pulmonary Embolism? Grand Rounds Discussion From Beth 1161
A Novel International Monkeypox Outbreak
Female primary care physicians (PCPs) conduct fewer but longer patient visits and provide more counseling and shared decision making than male PCPs. This type of care is valued by patients and may be linked to better out-
Research and Reporting Methods
D. Daskalakis, R.P. McClung, L. Mena, and J. Mermin S. Lewin, H. Macdonald, E. McFarlane, J. Meerpohl, Z. Munn, M.H. Murad, R.A. Mustafa, I. Neumann, R. Nieuwlaat, A. Nowak, J. Pardo Pardo, A. Qaseem, G. Rada, M. Righini, B. Rochwerg, M.X. Rojas-Reyes, D. Siegal, R. Siemieniuk, J.A. Singh, N. Skoetz, S. Sultan, A. Synnot, P. Tugwell, A. Turner, T. Turner, S. Venkatachalam, V. Welch, and W. Wiercioch Living practice guidelines are increasingly being used to
M.S. McDonagh, B.J. Morasco, J. Wagner, A.Y. Ahmed, R. Fu, D. Kansagara, and R. Chou
A. Adalja and T. Inglesby 1175
Strengthening Food and Nutrition Security to Promote Public Health in the United States
R. Crowley, O. Atiq, and D. Hilden 1172
R. El-Khoury, H.J. Schünemann, E.A. Akl, P. Alonso-Coello, B.S. Alper, Y.S. Amer, T. Arayssi, J.M. Barker, I. Bouakl, I. R.Boutron,Brignardello-Petersen, K. Carandang, S. Chang, Y. Chen, A. Cuker, F. El-Jardali, I. Florez, N. Ford, J. Grove, G.H. Guyatt, G.S. Hazlewood, T. Kredo, F. Lamontagne, M.W. Langendam,
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and women, respectively. Findings suggest that reliance on spirometry alone may result in underrecognition of emphysema in Black men and women.
ensure recommendations are responsive to rapidly emerging evidence. This article presents a framework to help guideline developers plan, produce, report, and disseminate living guideline projects.
Food insecurity is well known to adversely affect health. The American College of Physicians offers several policy recommendations to strengthen the federal response to food insecurity and empower physicians and other medical professionals to better address this growing problem.
Review
How the Gender Wage Gap for Primary Care Physicians Differs by Compensation Approach
1154
Few clinicians practicing in the United States have ever
J. Serchen, O. Atiq, and D. Hilden 1170 comes. But compensation plans that emphasize productivity pay female physicians less than comparable male physicians. This article estimates how the difference might change under different types of compensation plans.
The number of Americans aged 65 years or older is expected to increase in the coming decades, and more people will need long-term services and supports (LTSS). The American College of Physicians offers policy recommendations on LTSS for the growing number of Americans who will need high- quality, accessible, equitable, and affordable services.
I. Ganguli, K.L. Mulligan, R.L. Phillips, and S. Basu 1135
Ideas and Opinions
Israel Deaconess Medical Center
Beyond the Guidelines
A Framework for the Development of Living Practice Guidelines in Health Care
Effect of Molnupiravir on Biomarkers, Respiratory Interventions, and Medical Services in COVID-19
1126
seen a case of monkeypox infection. However, a new, unusual, multinational outbreak of monkeypox that is unfold- ing rapidly makes it important to know what a case might look like to enable rapid, appropriate medical and public health interventions.
Monkeypox: Avoiding the Mistakes of Past Infectious Disease Epidemics
I.K. El Mikati, J. Khabsa, T. Harb, M. Khamis, A. H.Agarwal,Pardo-Hernandez, S. Farran, A.M. Khamis, O. El Zein,
Updated guidelines on treatment for venous thromboembolism offer many conditional recommendations, particularly in cases of patients with transient risk factors. In this article, a hematologist and a cardiology and vascular medicine specialist discuss the care of a patient with pulmonary embolism with reference to these guidelines.
Z. Kanjee, J.A. Freed, B.A. Carroll, and E.E. Reynolds
In this article, experts from the Centers for Disease Control and Prevention discuss what is currently known about the ep- idemiology and clinical manifestations of recent monkeypox cases and outline how best to work with patients and com- munities to recognize the illness and limit its further transmis- sion while avoiding stigma and bias.
Continued on page I13
an infectious disease risk that may herald yet another unprecedented epidemic.
V. Chopra Embarking on residency training in the wake of the 1195
In their article, Agarwal and colleagues provided important evidence that physicians are not routinely using available codes to bill services for which their patients are eligible, with some services coded for less than 1% of the eligible patient population. The editorialist discusses why many physicians are underusing these codes.
CME/MOC activity available at Annals.org
Beyond Race: A Wake-up Call for Drug Therapy 1187 Informed by Genotyping
important window into our understanding of how health
Editorials
Small Solutions for Primary Care Are Part of a Larger Problem
A Rich Vein
In the Clinic
J. Pinkney 1199
Update Alert (available at Annals.org)
As the monkeypox outbreak grows, health care workers must understand the threat and be prepared to address
D. Chick 1189
Major Update 2: Remdesivir for Adults With COVID-19
Eating Disorders ITC113
Many efforts that support U.S. primary care focus on additional payments to clinicians for specific primary care serv- ices. But these efforts may not recognize the extra effort needed to provide the services. This essay proposes an alternative approach.
J. Coulehan
Cannabinoids for Chronic Pain: Translating Systematic Review Findings Into Clinical Action
On Being a Doctor 1196
COVID-19 pandemic presents new challenges. This editorial offers guidance as new interns navigate the coming year and beyond.
Upon the Welcoming of the New Interns to the Profession: May the Force Be With You
ACP Journal Club JC85 The Best New Evidence for Patient Care
M. Izmaylov
1181 Living Practice Guidelines Require Robust and Continuous Iteration and Uptake
Adding New Fuel to the Fire: Monkeypox in the Time 1183
1191
T. Li and M. Michaels 1193
K.F. Boehnke and D.J. Clauw
Who Was She?
Mapping the Color Line: Racial/Ethnic and Gender 1185
Correspondence (available at Annals.org)
H. Lee and K.M. Harris
In their article, Johnson and colleagues estimated life expectancy at birth in the United States by race/ethnicity, sex, and state from 1990 to 2019. The editorialists discuss how the findings of state-level differences provide an
D.M. Tarn, N.S. Wenger, and K.C. Stange
Medicare Codes for Primary Care: Expansions With Limitations
Bedside Manner 1197 and well-being can vary drastically within our country.
1179
G. Sirugo and A. Wonkam
Evidence indicates that clinicians are not engaging in routine social needs screening. This commentary describes benefits of social-screening initiatives and recommends ways to increase the likelihood that social screening contributes to improvements in patient, provider, and population health.
Letters
equity and unique factors for public health guidelines, and harmonization to prevent duplication of efforts. of COVID 19 Implications for Health Care Personnel
Ad Libitum
McDonagh and colleagues’ systematic review investigatedthe benefits and harms of cannabinoids for treating chronic pain. The editorialists discuss the limitations and strength of the available evidence and share their own advice for engaging with patients interested in using cannabis to treat chronic pain.
Disparities in Life Expectancy Across the United States
When There Is Value in Asking: An Argument for Social Risk Screening in Clinical Practice
E. Byhoff and L.M. Gottlieb
T.N. Palmore and D.K. Henderson
In their article, Dickson and colleagues reported a retrospective cohort study of the association between azathio- prine discontinuation due to toxicity and selfidentified race and genetic variation. The editorialists discuss the critical questions that the research findings elicit.
In their article, El Mikati and colleagues presented a frame- work for developing living guidelines. The editorialists dis- cuss how future iterations of the framework could include considerations such as codevelopment of computable liv- ing guidelines, coordinated dissemination of written and computable formats, perspectives that account for health
Continued on page I-14 I-13
Video Summary
Web Exclusives Only in Annals, Only Online Annals.org
Opioid Use Disorder Surgery for Mild PTH
I-14
Video summaries of selected Annals articles. Annals.org/videosummary learning. Annals.org/consultguys
Expert-curated content relevant to hospital medicine. Annals.org/hospitalists
Masthead and Journal Information I-3
Videos with a unique perspective on real-world cases. If you’re not watching, you’re not
Cover photograph by Jill Jackson
Inpatient Notes: Improving Medication Reconciliation in Hospitals
Selected Annals content and structured activities
Cannabis-Based Products for Chronic Pain
Dr. Mom: Rounding in Late June 2022
Endocarditis Prophylaxis for Patients With TAVR CME/MOC activity available at Annals.org
G.E. Farris
J.L. Schnipper Dive J. Wineke
On Call Dr. Bob Centor’s podcast discusses timely and influential Annals articles with a guest expert. Annals.org/oncall
Annals
Continuing Medical Education I-5 Classified Services Begin on I-25
Original graphic narratives and animations: care beyond words. Annals.org/graphicmedicine for teaching. Annals.org/educators
CME/MOC activities available at Annals.org
IMAGE OF THE MONTH
Illustration of the confluence of varied considerations influencing personcentered revascularization decisions for older adults. For full details, see "An ageold dilemma: Defining the optimal revascularization approach in older adults” on page 2205.
AUGUsT 2022 VOLUME 70 ■ ISSUE 8
EDITOR’S CHOICE ARTICLE
Victoria D. Powell, Navasuja Kumar, Andrzej T. Galecki et al.
Bad company: Loneliness longitudinally predicts the symptom cluster of pain, fatigue, and depression in older adults
AGSF, Editor-in-Chief I ALEXANDER
G. OUSLANDER,
Editor Editorials ■ Clin-Star corner: A new series featuring practice-changing articles in medical, surgical, and related specialties Lona Mody, Thomas M. Gill and Susan J. Zieman ■ A paradigm shift Loneliness as a root cause of symptom distress among older adults Ashwin A. Kotwal Special Article ■ Survive and thrive: Personal stories of persistence and resilience in aging research Melisa L. Wong, Cynthia J. Brown, Dalane W. Kitzman et al. Clinical Investigation ■ Elderspeak communication and pain severity as modifiable factors to rejection of care in hospital dementia care Clarissa A. Shaw, Caitlin Ward, Jean Gordon et al. Commentary ■ Dear geriatrician From surgeon Samuel M. Miller, Muhammad Abbas, Frances Y. Hu et al. FULL TABLE OF CONTENTS INSIDE
JOSEPH MD, K. SMITH, MD, MS, MPH, Executive Editor I DEBRA SALIBA, MD, MPH, AGSF, Executive
Treatment of hypertension should be based on research-grade office determinations supplemented by out-of-office measurements, including both home and 24-hour ambulatory, if available.
COMMENTARIES
Progression of chronic kidney disease is the primary driver of adverse chronic kidney disease- related outcomes. Racial and ethnic minorities suffer greater risk for chronic kidney disease progression.
1035 The CMS Vaccine Mandate at the Supreme Court: A Hippocratic Imperative Eli Y. Adashi and I. Glenn Cohen
1040 Diversity is the Answer Martin A. Samuels
REVIEWS
The Green Journal September 2022 Volume 135/Number 9 MEDICINE ® CONTENTS
THE AMERICAN JOURNAL of
1033 New Clinical Guidelines for the Diagnosis and Treatment of Heart Failure: Snatching Life from the Jaws of Death William H. Frishman and Joseph S. Alpert
Microvascular dysfunction results in tissue damage and progressive organ Diagnosisfailure. of microvascular dysfunction affecting the heart, brain, kidney, lung, or retina should prompt evaluation of other possible affected organs.
1043 Controversies in Hypertension I: The Optimal Assessment of Blood Pressure Load and Implications for Treatment Edward J. Filippone, Andrew J. Foy, and Gerald V. Naccarelli
1051 Primary Medical Care Integrated with Healthy Eating and Healthy Moving is Essential to Reduce Chronic Kidney Disease Progression Donald E. Wesson, Vandana NavdeepMathur, Tangri, Sarah Hamlett, David A. Bushinsky, and L. Ebony Boulware
1037 Extending Coronary Artery Calcium Scanning with CT Coronary Angiography in the Primary Care JenniferSettingFebbo, R. Philip Eaton, Samuel Wann, and David S. Schade
1059 Microvascular Dysfunction as a Systemic Disease: A Review of the Evidence Daniel S. Feuer, Eileen M. Handberg, Borna Mehrad, Janet Wei, C. Noel Bairey Merz, Carl J. Pepine, and Ellen C. Keeley
1041 Diagnostic Accuracy in the 21st Century - No Time for Conceit Ami Schattner
A7
IMAGES IN RADIOLOGY
Joshua I. Barzilay, Petra Buzkova, Lewis H. Kuller, Jane A. Cauley, Howard A. Fink, Kerry Sheets, John A. Robbins, Laura D. Carbone, Rachel E. Elam, and Kenneth J. Mukamal
1101 The Association of Lipids and Lipoproteins with Hip Fracture Risk: The Cardiovascular Health Study
CLINICAL RESEARCH STUDIES
1109 Face Off: 3D-Printed Masks as a CostEffective and Reusable Alternative to N95 Respirators: A Feasibility Study
3D-printed respirators may provide a useful alternative to N95 masks in protecting against respiratory pathogens such as the SARS-CoV-2 virus. Fit testing results demonstrate that certain 3D-printed mask designs may exceed the fit of N95 masks.
Mario Schootman, Brian C. Steinmeyer, Ling Chen, Robert M. Carney, Michael W. Rich, and Kenneth E. Freedland
Adults with type 2 diabetes with microvascular disease had a higher risk of incident atrial fibrillation compared with those without microvascular disease. Microvascular disease may be involved in the pathogenesis of atrial fibrillation in type 2 diabetes
1093 Burden of Microvascular Disease and Risk of Atrial Fibrillation in Adults with Type 2 ArnaudDiabetesD. Kaze, Matthew F. Yuyun, Gregg C. Fonarow, and Justin B. Echouffo-Tcheugui
DIAGNOSTIC DILEMMA
1075 An Unusual Case of Sarcoidosis: Hypercalcemia and Normal Sized Lymph MelissaNodes Wang, Lakshmi Puttagunta, and Pen Li
IMAGES IN DERMATOLOGY
Elevated lipid and lipoprotein levels were associated with hip fracture risk, suggesting an unanticipated protective benefit of lipidlowering medications in people with elevated LDL-C levels.
1080 Never Feed Birds in the Hot Tub! A Case of Bird-Fancier’s Lung Maria Rechtin and Matthew Koroscil
1078 The Great Imitator: Primary Syphilis Clinically Mimicking Oral Squamous Cell Carcinoma Elisabetta Magnaterra, Vieri Grandi, and Luigi Pisano
Multimorbidity prevalence is increasing across racial and ethnic groups in the United States, with blacks and individuals of lower income exhibiting persistently higher prevalence. No significant change was seen in black-white multimorbidity prevalence disparity.
Marc Levine, Lance Levine, Helen Xun, Adam Gerber, Michael Antonietti, Prakash J. Mathew, and Devinder Singh
1116 Influence of Neighborhood Conditions on Recurrent Hospital Readmissions in Patients with Heart Failure: A Cohort Study
1069 Update in Outpatient General Internal Medicine: Practice-Changing Evidence Published in 2021 Majken T. Wingo, Jill M. Huber, Shari L. Bornstein, Karna K. Sundsted, Karen F. Mauck, Jason H. Szostek, Jason A. Post, and Mark L. Wieland
High area-poverty rate, rather than built environment or perceived neighborhood conditions, was associated with increased risk for readmission in patients with heart failure. Improving diabetes and blood pressure control or structural aspects of impoverished areas may help reduce hospital readmissions.
This summary of recently published evidence may help internists efficiently identify and apply the latest information to patient care in the outpatient setting. Basing their selection on relevance to outpatient internal medicine, impact on practice, and strength of evidence, the authors present seven topics briefly detailing significant new research.
1083 Temporal Trends in Racial and Ethnic Disparities in Multimorbidity Prevalence in the United States, 1999-2018 C´ esar Caraballo, Jeph Herrin, Shiwani Mahajan, Daisy Massey, Yuan Lu, Chima D. Ndumele, Elizabeth E. Drye, and Harlan M. Krumholz
A8
REVIEW
e318 Reversed Halo Sign on Chest Computed Tomography in a 33-Year-Old Man Without Immunosuppression
Sarah Dr€ager, Kathleen Jahn, Moritz Vogt, Helmut Hopfer, Diego Kyburz, and Michael Osthoff
The use of long-term continuous monitoring can significantly increase the possibility of detecting atrial fibrillation; this may prove to be a cost- effective tool in secondary stroke Someprevention.patients with embolic stroke of undetermined source may benefit from anticoagulation.
In people who inject drugs and have infective endocarditis, misuse of the peripherally inserted central catheter line predicted higher risk of recurrent infective endocarditis and Avoidancedeath. of peripherally inserted central catheters and use of intravenous peripheral therapy did not reduce mortality.
e321 Diffuse Planar Xanthoma Involving the Face in a Mask-Like Distribution Shi Yu Derek Lim, Michelle Weiting Liang, and Wei Na Suzanne Cheng
AJM ONLINE
CLINICAL RESEARCH STUDIES
e324 Peripherally Inserted Central Catheter Line Misuse Among People Who Inject Drugs
e305 Management of Antiplatelet Therapy in Patients with Coronary Stents Undergoing Noncardiac NidhiSurgeryRohatgi, James L. Zehnder, and Nathaniel R. Smilowitz
1124 Artificial Intelligence-Based Stethoscope for the Diagnosis of Aortic Stenosis Tamer Ghanayim, Lior Lupu, Sivan Naveh, Noa Bachner-Hinenzon, Doron Adler, Salim Adawi, Shmuel Banai, and Avinoam Shiran
e308 It Is Time to Abandon the Use of Body Surface Area Derived From a 100-Year-Old Formula Haoyi Zheng
While on Therapy for Infective Endocarditis Janica Adams, Tara Elton-Marshall, Esfandiar Shojaei, and Michael Silverman
e337 Rates of In-Hospital Decongestion and Association with Mortality and Cardiovascular Outcomes Among Patients Admitted for Acute Heart Failure
Please note that articles with an “e” page designation are available only in the online version of the Journal at www.amjmed.com.
COMMENTARIES
IMAGES IN DERMATOLOGY
e311 Long-Term Cardiac Monitoring After Embolic Stroke of Undetermined Source: Search Longer, Look DimitriosHarderSagris, Stephanie L. Harrison, Benjamin J.R. Buckley, George Ntaios, and Gregory Y.H. Lip
Wendy McCallum, Hocine Tighiouart, Jeffrey M. Testani, Matthew Griffin, Marvin A. Konstam, James E. Udelson, and Mark J. Sarnak
e353 Correlation of Pyuria and Bacteriuria in Acute BoCareCheng, Mufrad Zaman, and William Cox
The presence of white blood cells in urine has poor sensitivity and specificity to predict a positive urine culture. Pyuria alone is an inadequate test to diagnose a urinary tract infection and should not be used as a standalone test to guide antibiotic therapy.
DIAGNOSTIC DILEMMA
An electronic stethoscope with infrasound capabilities, which can accurately diagnose aortic stenosis using artificial intelligence, has been developed. This AI-based stethoscope can be used for wide screening of patients for the presence of significant aortic stenosis.
In patients with heart failure with reduced ejection fraction admitted for acute heart failure, more rapid decongestion was associated with reduced risk of mortality and subsequent acute heart failure hospitalizations. Faster rates of decongestion were not associated with cardiovascular harm.
A9
1134 Risk Factors for Climate-Related Health Effects in an Ambulatory Population
Xiaopeng Guo, Honglin Hao, Hao Xing, and Yi Guo
LETTERS
e374 The Life-Changing Implications of Evaluation of Jugular Venous Pressure Oscar M.P. Jolobe
A10
e376 Revealing the Truth of Severe Right Axis Deviation Due to Large Hiatal YiHerniaLi,Tong Liu, and Zhibing Lu
e372 Regarding the Surgical Management of Vertebral Compression Fractures Andr´ es Rocha-Romero
Joanne Bernstein, Caitlin Rublee, Cynthia Kay, and Jeffrey L. Jackson
e361 Making the Heart Grow Stronger: Reversal of Dilated Cardiomyopathy in an Elderly Patient Andrew Jamieson
1142 Ghost of Summer, 1988 Richard Scott Morehead
e359 Superior Vena Cava Thrombosis Etienne Rivi` ere and Claire Bazin
e368 Idiopathic Basal Ganglia Calcifications and Parkinson’s Disease
Joshua Lee, Jonathan Cheah, and Prakash Paudel
e375 The DavidReplyL.Jardine
1137 The Importance of Adding Discernment to the Acting Internship A Necessary Shift in Culture Toward Competency-Based Metrics Adam M. Garber, Allison H. Ferris, and T. Robert Vu
BRIEF OBSERVATIONS
PERSONOMICS
e366 Crowned Dens Syndrome Presenting as Altered Mental Status
e370 Wilson Disease: Never Too Late Anand K. Annamalai, Venkatesh N. Prajna, Gunja Chowdhury, Radhakrishnan Santhi, Mariappan Kannan, Srinivasan Vedantham, and Mark Gurnell
e373 The DanielReplyAlsoof and Alan H. Daniels
e377 The PhilipReplyL.Mar and Christina Tsai
MEDICAL HUMANITIES
AAIM PERSPECTIVES
1144 The Two Pandemics Michelle M. Kittleson
e364 Intolerable Unilateral Hip Pain: Clues from the JeniceHistoryX. Cheah, Naziheh Assarzadegan, Jyotsna Ghosh, Caoilfhionn M. Connolly, and Allan C. Gelber
CLINICAL COMMUNICATIONS TO THE EDITOR
For Author Guidelines please visit www.pediatrics.org
S E P T E M B E R 2022 • V O L U M E 150 • NUM B E R 3
· The US routine childhood immunization program continues to yield considerable reductions in incidence across all 14 diseases targeted by the program.
Justin Carrico, Elizabeth M. La, Sandra E. Talbird, Ya-Ting Chen, Mawuli K. Nyaku, Cristina Carias, Claire E. Mellott, Gary S. Marshall, Craig S. Roberts
SL, Garber MD, Rice-Conboy E, et al. 2016;137(1):e20150851.
Neonatal Outcomes of Mothers With a Disability 41
Samplepublications.aap.org/journalscitationformat:Ralston
· The US routine childhood immunization program saves $55.1 billion in soci- etal costs while preventing substantial unnecessary morbidity and mortality.
Racism and Quality of Neonatal Intensive Care: Voices of 44 Black Mothers
Brittany L. Willer, Joseph D. Tobias, Markita L. Suttle, Olubukola O. Nafiu, Christian Mpody
ARTICLES
Hilary K. Brown, Simon Chen, Astrid Guttmann, Susan M. Havercamp, Susan L. Parish, Joel G. Ray, Simone N. Vigod, Lesley A. Tarasoff, Yona Lunsky
· Through interviews with Black mothers of preterm infants hospital- ized in the NICU, this study examines their perspectives of quality of care and effects of racism.
· We used the Delphi method to generate expert consensus about how parents and caregivers can support mental health and beingwell-oftransgender and gender diverse children.
· Newborns of women with disabilities have elevated risk for neonatal complications, demonstrating the need for customized tionpreconcep-andprenatal care, and tailored, family-centered newborn care.
contents
Rachel E. Witt, Mia Malcolm, Bryanne N. Colvin, Monique R. Gill, Joel Ofori, Shireen Roy, Shannon N. Lenze, Cynthia E. Rogers, Eve R. Colson
· Authors of this study evaluated racial and ethnic disparities in cen- tral line associated bloodstream infections using a generalizable cohort of children who received a central venous catheter.
instagram.com/aap_pediatricsfacebook.com/aappeds twitter.com/aap_peds
Developing Parenting Guidelines to Support Transgender and 48 Gender Diverse Children’s Well-being
Sabra L. Katz-Wise, Allegra R. Gordon, Kendall J. Sharp, Natalie Penhale Johnson, Laura M. Hart
Trends of Racial/Ethnic Disparities in Pediatric Central Line 47 Associated Bloodstream Infections
Impact of Routine Childhood Immunization in Reducing 36 Vaccine-Preventable Diseases in the United States
®
P E D I A T R I C S
Value of the Immunization Program for Children in the 2017 37 US Birth Cohort
Sandra E. Talbird, Justin Carrico, Elizabeth M. La, Cristina Carias, Gary S. Marshall, Craig S. Roberts, Ya-Ting Chen, Mawuli K. Nyaku
A3
Changes in BMI During the COVID-19 Pandemic 53
Sex Assigned at Birth Ratio Among Transgender and Gender 49 Diverse Adolescents in the United States
· Utilizing data from a national transgender youth sample, this study reveals the sex assigned at birth ratio favors transgender adolescents assigned male sex at birth.
E
Julianne E. Burns, Cary Thurm, James W. Antoon, Carlos G. Grijalva, Matt Hall, Adam L. Hersh, Gabrielle Z. Hester, Emilie Korn, Mario A. Reyes, Samir S. Shah, Balagangadhar R. Totapally, Ronald J. Teufel, II
P D I A T R I C S
Lily Payvandi, Emily Trudell Correa, Jonathan Hatoun, Heather O’Donnell, Louis Vernacchio
· We evaluated medication utilization and adherence to treatment guidelines in children hospitalized for coronavirus disease 2019 across the United States.
· Child problematic media use was elevated when parents experienced structural stressors and psycho- logical distress.
Emily Kroshus, Pooja S. Tandon, Chuan Zhou, Ashleigh M. Johnson, Mary Kathleen Steiner, Dimitri A. Christakis
Robert Whittaker, Margrethe Greve-Isdahl, Håkon Bøås, Pål Suren, Eirik Alnes Buanes, Lamprini Veneti
A4 ®
Trends in Telehealth Antibiotic Prescribing for Children Through the COVID-19 Pandemic 51
· We describe telehealth antibiotic prescribing patterns within our statewide pediatric primary care network during the coronavirus disease 2019 pandemic.
ARTICLES (continued)
· This study evaluates whether the annual rate of change in child body mass index was higher during the pandemic than in previous years.
· We compare the risk of hospitalization in unvaccinated persons between waves of the SARS-CoV-2 Alpha, Delta and Omicron variants in Norway.
Jack L. Turban, Brett Dolotina, Dana King, Alex S. Keuroghlian
Problematic Child Media Use During the COVID-19 Pandemic 52
Emily A. Knapp, Yanan Dong, Anne L. Dunlop, Judy L. Aschner, Joseph B. Stanford, Tina Hartert, Susan L. Teitelbaum, Mark L. Hudak, Kecia Carroll, Thomas G. O’Connor, Cindy T. McEvoy, T. Michael O’Shea, Susan Carnell, Margaret R. Karagas, Julie B. Herbstman, Dana Dabelea, Jody M. Ganiban, Assiamira Ferrara, Monique Hedderson, Traci A. Bekelman, Andrew G. Rundle, Akram Alshawabkeh, Diane Gilbert-Diamond, Rebecca C. Fry, Zhanghua Chen, Frank D. Gilliland, Rosalind J Wright, Carlos A. Camargo, Jr, Lisa Jacobson, Barry M. Lester, Christine W Hockett, Marie L. Hodges, Aruna Chandran, on behalf of program collaborators for Environmental Influences on Child Health Outcomes
COVID-19 Hospitalization Among Children <18 Years by Variant Wave in Norway 54
Health Impairments in Children and Adolescents After Hospitalization for Acute COVID-19 or MIS-C 55
· This multicenter prospective study evaluates risk factors for postdischarge sequelae in children and adolescents after hospital admission for acute coronavirus disease 2019 or multisystem inflammatory syndrome in children.
contents
S E P T E M B E R 2022 • V O L U M E 150 • NU M B E R 3
Medications and Adherence to Treatment Guidelines Among Children Hospitalized With 50 Acute COVID-19
Aline B. Maddux, Laura Berbert, Cameron C. Young, Leora R. Feldstein, Laura D. Zambrano, Suden Kucukak, Margaret M. Newhams, Kristen Miller, Madyson M. FitzGerald, Jie He, Natasha B. Halasa, Natalie Z. Cvijanovich, Laura L. Loftis, Tracie C. Walker, Stephanie P. Schwartz, Shira J. Gertz, Keiko M. Tarquinio, Julie C. Fitzgerald, Michele Kong, Jennifer E. Schuster, Elizabeth H. Mack, Charlotte V. Hobbs, Courtney M. Rowan, Mary A. Staat, Matt S. Zinter, Katherine Irby, Hillary Crandall, Heidi Flori, Melissa L. Cullimore, Ryan A. Nofziger, Steven L. Shein, Mary Glas Gaspers, Janet R. Hume, Emily R. Levy, Sabrina R. Chen, Manish M. Patel, Mark W. Tenforde, Edie Weller, Angela P. Campbell, Adrienne G. Randolph, for the Overcoming COVID-19 Investigators
· Among adolescents in Southern California, use of flavored tobacco-free oral nicotine products was more common than all other nicotine and tobacco products except for e-cigarettes.
· This randomized controlled trial compares intermittent tiotropium bromide treatment with intermittent fluticasone propionate treatment and with as-needed albuterol sulfate treatment in early childhood epi- sodic wheezing.
ARTICLES (continued)
Julia Rosenberg, Veronika Shabanova, Sarah McCollum, Mona Sharifi
Battery-Related Emergency Department Visits in the United States: 2010 2019 76
P E D I A T R I C S
Amanda S. Nitschke, Jalisa L. Karim, Bruce A. Vallance, Celeste Bickford, Angie Ip, Nancy Lanphear, Bruce Lanphear, Whitney Weikum, Tim F. Oberlander, Gillian E. Hanley
· Compared with citizen children with US-born parents, uninsurance rates among children from mixed- status families increased between 2017 and 2019, and the disparity widened over time.
· From a microbiome gut brain axis perspective, this population-based cohort study explores an associ- ation between antibiotic use during labor and delivery with autism spectrum disorder.
· This study captures the epidemiology of battery-related emergency department visits among children aged 18 years from 2010 to 2019 and compares to previous findings.
S E P T E M B E R 2022 • V O L U M E 150 • NU M B E R 3
A5 ®
Insurance and Health Care Outcomes in Regions Where Undocumented Children Are 61 Medicaid-Eligible
Kevin H. Nguyen, Ira B. Wilson, Anya R. Wallack, Amal N. Trivedi
Outcomes After Positive Syphilis Screening 65
Children’s Health Insurance Coverage and Parental Immigration Status: 2015 2019 64
· Analyzing the National Survey of Children’s Health 2019, we found lower uninsured rates and less forgone care where children are Medicaid-eligible, regardless of documentation status.
contents
Text Message Reminders for the Second Dose of Influenza Vaccine for Children: An RCT 71
· For 75,056 pregnancies, we explored the influence of false positive and true positive maternal syphilis screens on maternal and infant syphilis evaluations and treatment.
Child Health Status and Health Care Use in Grandparent- Versus Parent-Led Households 70
Classification of Children and Adolescents With Avoidant/Restrictive Food Intake Disorder 75
Autism Risk and Perinatal Antibiotic Use 74
Adolescent Use of Flavored Non-Tobacco Oral Nicotine Products 56
Melissa S. Stockwelll, Laura P. Shone, Ekaterina Nekrasova, Chelsea Wynn, Alessandra Torres, Miranda Griffith, Justine Shults, Rebecca Unger, Leigh Ann Ware, Chelsea Kolff, Donna Harris, Lindsay Berrigan, Heather Montague, A. Russell Localio, Alexander G. Fiks
Nicola P. O’Connor, Patrick C. Burke, Sarah Worley, Kamran Kadkhoda, Oluwatosin Goje, Charles B. Foster
Mark D. Chandler, Khudeja Ilyas, Kris R. Jatana, Gary A. Smith, Lara B. McKenzie, J. Morag MacKay
· In this randomized controlled trial, we assessed the effectiveness of personalized text message reminders in increasing overall and timely second dose of influenza vaccine receipt.
Alyssa F. Harlow, Erin A. Vogel, Alayna P. Tackett, Junhan Cho, Dae-Hee Han, Melissa Wong, Myles G. Cockburn, Steve Y. Sussman, Jennifer B. Unger, Adam M. Leventhal, Jessica L. Barrington-Trimis
Anne Kotaniemi-Syrja€nen, Timo Klemola, Petri Koponen, Outi Jauhola, Henrikka Aito, Kristiina Malmstr€om, L. Pekka Malmberg, Eero Rahiala, Seppo Sarna, Anna S. Pelkonen, Mika J Ma€kela€
Intermittent Tiotropium Bromide for Episodic Wheezing: A Randomized Trial 57
· This study compares diagnosed child health conditions, health care utilization, and caregiver burden for a nationally representative sample of children in grandparent-led versus parent-led households.
Deepa S. Joshi, Lydie A. Lebrun-Harris
· This study confirms that avoidant restrictive food intake disorder is a heterogeneous diagnosis with 3 distinct classes corresponding to subtypes described in the literature.
Debra K. Katzman, Tim Guimond, Wendy Spettigue, Holly Agostino, Jennifer Couturier, Mark L. Norris
FROM THE AMERICAN ACADEMY OF PEDIATRICS
Lois K. Lee, Michael R. Flaherty, Ashley M. Blanchard, Maneesha Agarwal, THE COUNCIL ON INJURY, VIOLENCE, AND POISON PREVENTION
Children in Immigrant Families Deserve Health Care 62 Fernando S. Mendoza, Lee Sanders, David D. Laitin
Maternal and Congenital Syphilis: A Call for Improved Diagnostics and Education 66 Jessica E.P. Williams, Rachel J. Graf, Charles A. Miller, Ian C. Michelow, Pablo J. Sa´nchez
Trends in the Diversity of Pediatric Faculty: 2000 to 2020 77
Emma A. Omoruyi, Colin J. Orr, Greg Russell, Kimberly Montez
S E P T E M B E R 2022 • V O L U M E 150 • NU M B E R 3
“Is This Mic On?” Improving NICU Quality of Care by Amplifying Black Mothers’ Voices 45 Kasee L. Houston, Valencia P. Walker
ARTICLES (continued)
Personalized Texts Can Boost Receipt of Second Influenza Shot for Young Children 72 Rebecca R. Ortiz, Tamera Coyne-Beasley
Policy HelmetStatementsUseinPreventing Head Injuries in Bicycling, Snow Sports, and Other Recreational Activities and Sports
COMMENTARIES
Creating Work and Learning Environments Free of Gender-Based Harassment in Pediatric Health Care
Birth Outcomes of Infants Born to Mothers With Disability: A Population at Risk 42 Kathleen E. Hannan, Sunah S. Hwang, Stephanie L. Bourque
Angelo P. Giardino, Mark L. Hudak, Beena G. Sood, Stephen A. Pearlman, THE COMMITTEE ON CHILD HEALTH FINANCING 124116109103
A6 ®
contents
· This repeat cross-sectional study evaluates trends in pediatric faculty diversity from 2000 to 2020 and compares racial/ethnic representation between pediatric faculty and the United States population.
Antoinette Laskey, Suzanne Haney, Sarah Northrop, THE COUNCIL ON CHILD ABUSE AND NEGLECT Considerations in the Determination of Medical Necessity in Children: Application to Contractual Language
Julie Story Byerley, Nancy A. Dodson, Tiffany St. Clair, Valencia P. Walker, THE COMMITTEE ON PEDIATRIC WORKFORCE
Protecting Children From Sexual Abuse by Health Care Professionals and in the Health Care Setting
Vaccines Are Profoundly Effective, and We Can’t Stop There 38 Michael D. Warren, Monique Fountain Hanna
See It to Be It: Diversity and Inclusion in Academic Pediatrics Starts at the Top 78 Joseph L. Wright, W. Christopher Golden Supraglottic Airways, Tennis, and Neonatal Resuscitation 82 Stephen G. Flynn, Mary Lyn Stein, John E. Fiadjoe
P D I A T R I C S
E
Intermittent Tiotropium for Episodic Wheezing 58 Daniel J. Shapiro, Ann Chen Wu
Applying an Equity Lens to Clinical Practice Guidelines: Getting Out of the Gate 22 Joseph L. Wright, Maria E. Trent
Helmet Use in Preventing Head Injuries in Bicycling, Snow Sports, and Other Recreational Activities and Sports
Jonathan L. Slaughter, Alex R. Kemper, Thomas B. Newman
A7 ®
Alex R. Kemper, Thomas B. Newman, Jonathan L. Slaughter, M. Jeffrey Maisels, Jon F. Watchko, Stephen M. Downs, Randall W. Grout, David G. Bundy, Ann R. Stark, Debra L. Bogen, Alison Volpe Holmes, Lori B. Feldman-Winter, Vinod K. Bhutani, Steven R. Brown, Gabriela M. Maradiaga Panayotti, Kymika Okechukwu, Peter D. Rappo, Terri L. Russell
ADVOCACY CASE STUDY
Scope of Health Care Benefits for Neonates, Infants, Children, Adolescents, and Young Adults Through Age 26
e-Policy Pages www.pediatrics.org
P E D I A T R I C S
RESEARCH BRIEFS
Race and Ethnicity of Pediatric Trainees and the Board-Certified Pediatric Workforce 1 Adam L. Turner, Crista J. Gregg, Laurel K. Leslie
contents
Lois K. Lee, Michael R. Flaherty, Ashley M. Blanchard, Maneesha Agarwal, and THE COUNCIL ON INJURY, VIOLENCE, AND POISON PREVENTION
The Parent’s Dilemma: Pediatric Assent in Research 5 Gianna McMillan
COVID-19 Vaccines in Infants, Children, and Adolescents
AMERICAN ACADEMY OF PEDIATRICS, COMMITTEE ON ADOLESCENCE
Mark L. Hudak, and THE COMMITTEE ON CHILD HEALTH FINANCING
AMERICAN ACADEMY OF PEDIATRICS, COMMITTEE ON ADOLESCENCE
COMMITTEE ON INFECTIOUS DISEASES
The Adolescent’s Right to Confidential Care When Considering Abortion
Clinical Practice Guideline Revision: Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation
FEATURE
Alexandre Lion: The Forgotten Inventor of Incubator Shows 12 Thijs Gras
Predicting the Need for Phototherapy After Discharge: Update for 2022 Phototherapy Guidelines 19 Michael W. Kuzniewicz, Sherian Xu Li, Charles E. McCulloch, Thomas B. Newman
PEDIATRICS PERSPECTIVES
S E P T E M B E R 2022 • V O L U M E 150 • NU M B E R 3
· Through a partnership between a pediatric hospital and faith-based and community organizations, we were able to increase pediatric influenza vaccinations over a 4-year period. Alexandra M.S. Corley, Stacey M. Gomes, Lori E. Crosby, Michelle Hopkins, Dena Cranley, Barbara Lynch, Monica Mitchell
Asset-Based Health Care for Children With Severe Neurologic Impairment 8 Elizabeth (Liz) Morris, Julie Hauer, Jori F. Bogetz
Technical Report: Diagnosis and Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation
Options Counseling for the Pregnant Adolescent Patient
FAMILY PARTNERSHIPS
Partnering With Faith-Based Organizations to Offer Flu Vaccination and Other Preventive Services 15
· A hybrid physical activity and nutrition-based intervention comprising of face-to-face and online components is highly recommended for children and adolescents with type 1 diabetes mellitus
Guidance for Cardiopulmonary Resuscitation of Children With Suspected or Confirmed COVID-19 87
· This study describes reductions in croup admission rates following education around evidence-based practice and implementation of a clinical guideline and orderset.
Ryan W. Morgan, Dianne L. Atkins, Antony Hsu, Beena D. Kamath-Rayne, Khalid Aziz, Robert A. Berg, Farhan Bhanji, Melissa Chan, Adam Cheng, Kathleen Chiotos, Allan de Caen, Jonathan P. Duff, Susan Fuchs, Benny L. Joyner, Jr., Monica Kleinman, Javier J. Lasa, Henry C. Lee, Rebecca E. Lehotzky, Arielle Levy, Mary E. McBride, Garth Meckler, Vinay Nadkarni, Tia Raymond, Kathryn Roberts, Stephen M. Schexnayder, Robert M. Sutton, Mark Terry, Brian Walsh, Carolyn M. Zelop, Comilla Sasson, Alexis Topjian, on behalf of the American Heart Association Emergency Cardiovascular Committee and Get with the Guidelines- Resuscitation Pediatric Task Force in Collaboration with the American Academy of AmericanPediatrics,Association for Respiratory Care, and American Society of Anesthesiologists
S E P T E M B E R 2022 • V O L U M E 150 • NU M B E R 3
Shefaly Shorey, Esperanza D. Ng, Evelyn C. Law, John C.M. Wong, Kah Yin Loke, Wilson W.S. Tam
· This review paper highlights recent developments worldwide in the epidemiology, screening, telemedicine, and treatment of retinopathy of prematurity.
STATE-OF-THE-ART REVIEW
Kourosh Sabri, Anna L Ells, Elizabeth Y. Lee, Sourabh Dutta, Anand Vineker
Vascular Complications in Children Following Button Battery Ingestions: A Systematic Review 84
Trends in Parents’ Confidence in Childhood Vaccines During the COVID-19 Pandemic 28 Megha D. Shah, Peter G. Szilagyi, Rashmi Shetgiri, Jeanne R. Delgado, Sitaram Vangala, Kyla Thomas, Rebecca N. Dudovitz, Nathalie Vizueta, Jill Darling, Arie Kapteyn
· This systematic review and meta-analysis compares the use of supraglottic airway devices with face masks for administering positive pressure ventilation at birth.
Olugbenga Akinkugbe, Adrian L. James, Olivia Ostrow, Tobias Everett, Nikolaus E. Wolter, Nicole K. McKinnon
· Through systematic review of published cases of pediatric button battery ingestions, we highlight risk factors for death among cases with vascular injury.
SPECIAL ARTICLE
· This article provides guidance to health care personnel regarding the provision of safe and effective resuscitation care to children and neonates with suspected or confirmed coronavirus disease 2019.
Use of a Clinical Guideline and Orderset to Reduce Hospital Admissions for Croup 88
Supraglottic Airways Compared With Face Masks for Neonatal Resuscitation: A Systematic Review 81
QUALITY REPORTS
contents
Race and Ethnicity in Neonatal Group B Streptococcal Disease in England: 2016 2020 33 Simon M. Collin, Alicia Demirjian, Catherine Swann, Theresa Lamagni
Physical Activity and Nutrition Interventions for Type 1 Diabetes: A Meta-analysis 85
REVIEW ARTICLES
®
Nicole K. Yamada, Christopher JD McKinlay, Bin Huey Quek, Georg M. Schm€olzer, Myra H. Wyckoff, Helen G. Liley, Yacov Rabi, Gary M. Weiner, on behalf of the INTERNATIONAL LIAISON COMMITTEE ON RESUSCITATION NEONATAL LIFE SUPPORT TASK FORCE
Vaccine Effectiveness of BNT162b2 Against Delta and Omicron Variants in Adolescents 25 Sarah A. Buchan, Lena Nguyen, Sarah E. Wilson, Sophie A. Kitchen, Jeffrey C. Kwong
RESEARCH BRIEFS (continued)
P E D I A T R I C S
Gabrielle Hester, Amanda J. Nickel, David Watson, Walid Maalouli, Kelly R. Bergmann
Retinopathy of Prematurity: A Global Perspective and Recent Developments 86
A8
Interdisciplinary Quality Improvement Project Increases Vitamin D Supplementation in Infants 89
P E D I A T R I C S
Ethan S. Vorel, Michael E. Russo, Jay J. Mehta, Ryan C. Borek, Melissa P. Muego, Janice A. Kelly, Morgan E. Greenfield
QUALITY REPORTS (continued)
· A novel approach allows kidney replacement therapy in newborns too small for traditional dialysis techniques.
Jennifer D. Chapman, Andrew S. Geneslaw, John Babineau, Anita I. Sen
A 7-Year-Old With Persistent Fever and Cough 91
· Severe acute respiratory syndrome coronavirus 2 illness occurs less frequently in children than in adults. We present a case of severe acute psychosis induced by severe acute respiratory syndrome 2coronavirusinfection.
Improving Ventilation Rates During Pediatric Cardiopulmonary Resuscitation 90
S E P T E M B E R 2022 • V O L U M E 150 • NU M B E R 3
Diagnostic Dilemmas
Scott M. Sutherland, Alexis S. Davis, Diana Powell, Jennifer Tanaka, Mayna Woo, Shellie Josephs, Cynthia J. Wong
· Dapsone may be a treatment option for gastrointestinal symptoms refractory to corticosteroids in children with IgA vasculitis.
Dapsone for Refractory Gastrointestinal Symptoms in Children With Immunoglobulin A Vasculitis
Zainab Bashir, Isabel M. Butt, Murali K. Vemuri, Tarekegn Geberhiwot
Masashi Yoshida, Ryusuke Nambu, Ryosuke Yasuda, Hirotaka Sakaguchi, Tomoko Hara, Itaru Iwama, Tatsuki Mizuochi
ERRATA Online only at www.pediatrics.org
· Interdisciplinary quality improvement effort to improve infant vitamin D supplementation rate in our pri- mary care resident clinic.
contents
Kidney Replacement Therapy in Low Birth Weight Preterm Newborns
CASE REPORTS Online only at www.pediatrics.org
Noah P. Diminick, Jamie M. Fey, Jonathan Bourque, Patricia Crosby, Leah Fox, Diana Tsai-Leonard, Heidi Morin, Kathleen Cyr, William Hewitt, Lorraine L. McElwain
Statement of Correction
A9 ®
· Implementation of a multifaceted educational initiative on ventilation during pediatric CPR is feasible and decreases the incidence of clinically significant hyperventilation.
· A previously healthy, fully immunized 7-year-old girl presented with a 7-week history of daily fevers and worsening cough with persistently elevated inflammatory markers.
Acute SARS-CoV-2 induced Psychosis in an Adolescent
http://doi.org/10.22201/fm.24484865e.2022.65.4 Vol. 65 No. 4. Julio-Agosto 2022 ISSN 0026 -1742 La salud mental, otro blanco de la pandemia Reacciones al estrés y aspectos psicoterapéuticos Nudo verdadero de cordón umbilical, hallazgo incidental al nacimiento. Reporte de 4 casos en un hospital de tercer nivel Aspectos relevantes de las epidemias y pandemias en México: desde la perspectiva del derecho sanitario Breve historia del Posgrado en Ciencias Médicas, Odontológicas y de la Salud El costo de seguir una vocación: la pintura. Johannes Vermeer illVo.65No.4Juo-Agosto2022
Director Dr.GermánE.FajardoDolci Editora
Traducciones: Lic.Alejandra NúñezFortoul. Fotografíadeportada: Imagentomadayeditadapor los biólogosArmandoZepeda-RodríguezyFrancisco
Dra. Teresa I. Fortoul van der Goes revfacmed@unam.mx
Dr. Carlos Fernández del Castillo Sánchez, Dr. Guillermo Fajardo Ortíz, Dr. Daniel Rembao Bojórquez, Dra. María Elisa Alonso Vilatela, Mtra. Gabriela Castañeda López, Dra. Ma. Elena Medina MoraIcaza,Dr.GuillermoJ.RuizArgüe- lles,Dr.José Ignacio Santos Preciado, Dr. Alberto Lifshitz Guinzberg, Dra.Yolanda LópezVidal,Dr. José Emilio Exaire Murad, Dra. Teresa Corona Vázquez, Dr. Felipe Vadillo Or- tega, Dr. Jaime Iván Velasco SalvadorRuizVelázquez,Dr.HoracioVidrioLópez,Dr.JoséOctavioSpeare,Dr.LeonardoViniegraVelázquez,Dr.UribeCarbajal.
UNAM,REVISTADELAFACULTADDEMEDICINADELA
Produccióneditorial: Imagia Comunicación Diseño, maquetación: Nayeli Zaragoza Corrección de estilo: Ulises Corona y Nayeli Zaragoza. Portal Web: Margarita Her- nández, Fidel Romero. Cuidado de edición: PedroMaríaLeón.
Asistente del editor
o 3669, licitud de contenido n.o 3101, ambos otorgados por la Comisión Calificadora de Publicaciones y Revistas Ilus- tradas de la Secretaría de Gobernación. Permiso SEPOMEX, registro para correspondencia de Publicaciones Periódicas No. delcontenidosreproducciónponsabilidadAutor.otorgadas203,versiónde03020,EnriquePP09-1026.ImpresaporG.P.GrupoStellar,S.A.deC.V.,Rebsamen314,Col.NarvartePoniente,C.P.DelegaciónBenitoJuárez,CDMX.ReservaDerechosalusoexclusivodeltítulodelavíacómputoNo.04-210-112612350300-ISSNversiónvíacómputo:2448-4865,ambosporelInstitutoNacionaldelDerechodeLostrabajosfirmadossonexclusivares-delosautores.Prohibidalatotaloparcialdelosartículosenestenúmerosinconsentimientoeditor.
Contenido Contents
Vol. 65, n.o 4, julio-agosto 2022 por la Facultad de Medici- na de la UNAM, Dirección: Ciudad Universitaria, circuito interior, edificio B, tercer piso, CP 04510, CDMX. Teléfonos: 56232154, de2004-TeresaWeb:56232508y56232300,ext.:43028y43029.Portalwww.facmed.unam.mx.Editorresponsable:I.FortoulvanderGoes.ReservadederechosalusoexclusivoNo.04-031713505800-102,ISSN:0026-1742.Licitudtítulon.
L.A. María del Rocío Sibaja Pastrana revfacmed@unam.mx
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Consejo editorial
Julio-Agosto 2022 1
Vol. 65, n.o 4, Julio-Agosto 2022
PasosNájera.DepartamentodeBiologíaCelular,Facultadde Medicina,UNAM. Versión electrónica en: www.revistafacmed.com Indizada en: Scielo, Periodica, Latindex, Imbiomed, Medigraphic, Sociedad Iberoamericana de Informa- ción Científica (SIIC Data Bases).
ISSN 0026-1742
AnayaDíaz,AlbertoArriagaLópez,AlfredoÁlvarezTorres,AndreaLeyvaGladysGeorginaCuevasArellano,CynthiaFabiolaChavira
Nudo verdadero de cordón umbilical, hallazgo incidental al nacimiento. Reporte de 4 casos en un hospital de tercer nivel..................................................... True Umbilical
Finding at Birth. Report of 4 Cases in a Third Level Hospital
Clinical Cases
EDITORIAL
Gastric and Gastroduode nal
ARTÍCULO DE REVISIÓN Review Article
Sergio Blanco Tapia, Lorena Jauregui Paravicini, Aarón Eduardo Carvajal Tapia
Mario Souza y Machorro
Cord Knot, Incidental
Editorial
Mental Health, Another Target of the Pandemic
La salud mental, otro blanco de la pandemia........................................................................
CASOS CLÍNICOS
Tricobezoar gástrico y gastroduodenal en Reportepediatría.de2 casos e implicaciones quirúrgicas....................................................................
Teresa I. Fortoul Van der Goes Reacciones al estrés y aspectos psicoterapéuticos.............................................................. Reactions to Stress and Psychotherapeutic Aspects
Trichobezoar in Pediatrics. Report of 2 Cases and surgical implications
2 RRevistaevista dede lala FFacultadacultad dede MMedicinaedicina dede lala UNAUNAMM | CASO CLÍNICO RADIOLÓGICO Radiological Clinical Case Haga su diagnóstico.....................................................38 Make your Diagnosis Marie del Trujeque Matos, Sergio Zurita Rojas Aspectos relevantes de las epidemias y pandemias en México: desde la perspectiva del derecho sanitario..............................40 Relevant Aspects of Epidemics and Pandemics in Mexico: From the Perspective of Health Law CastellanosGuadalupeNalleliWeber-Chuliá,GermánBazán-Miranda,LucíaCruz-Maldonado,AlbertoManuelÁngelesBreve historia del Posgrado en Ciencias Médicas, Odontológicas y de la Salud...........................................47 Brief history of the Postgraduate Program in Medical, Odontological and Health Sciences Alba Ochoa Cabrera, Teresa I. Fortoul van der Goes El costo de seguir una vocación: la pintura. Johannes Vermeer.....56 The Cost of Pursuing a Vocation: Painting Johannes Vermeer Teresa I. Fortoul van ARTE Y MEDICINA Art and Medicine CORRELACIONES HISTÓRICAS Historical Correlations ETICA Y PROFESIONALISMO MÉDICO Ethics and Medical Professionalism
Incluida en:
Aportacionesoriginales
Anestesia multimodal en paciente con enfermedad de Graves y tirotoxicosis: reporte de caso
El tiempo de atención y su impacto en la evolución del cáncer laríngeo
volumen 60 número 5 septiembre-octubre 2022
Supervivencia en pacientes pediátricos con neumonía en enfermedad por coronavirus 2019
Aportacionesoriginales
ISSN 0443-5117
Aportacionesoriginales
Depresión, ansiedad y calidad de vida en pacientes pediátricos con leucemia
ISSN electrónico 2448-5667
Artículosrevisiónde Citocinas proinflamatorias en el síndrome de ovario poliquístico
Irma Yolanda Castillo-López et al.
Elba Nelly Cano-Vázquez et al.
Efrén Murillo-Zamora et al.
María José Pagán-Rappo et al.
Manuel Ramón García-Sáenz et al.
Casos clínicos
Rev Med Inst Mex Seguro Soc. 2022;60(5):480-598. Los conceptos publicados son responsabilidad exclusiva de sus autores Teléfono (55) 5627 6900, extensión 21206
Correo electrónico: revista.medica@imss.gob.mx
CONSEJO EDITORIAL
Omar Chávez Martínez
EDITORES ASOCIADOS
COMITÉ EDITORIAL NACIONAL
Laura Cecilia Bonifaz Alfonzo
Lilia Patricia Bustamante Montes Universidad Autónoma del Estado de México Alfonso Martín Cueto Manzano Instituto Mexicano del Seguro Social Adolfo Chávez Negrete Academia Nacional de Medicina de México Juan Carlos de la Fuente Zuno Instituto Mexicano del Seguro Social María del Carmen García Peña Instituto Nacional de Geriatría Gerardo Guinto Balanzar Instituto Mexicano del Seguro Social Oscar Arturo Martínez Rodríguez Instituto Mexicano del Seguro Social Haiko Nellen Hummel
DISEÑO GRÁFICO
CONSEJEROS EMÉRITOS
José Halabe Cherem Academia Nacional de Medicina de México Marco Antonio Martínez Ríos Instituto Nacional de Cardiología Guillermo J. Ruiz Argüelles Academia Nacional de Medicina de México
BIBLIOMETRÍA E INDIZACIÓN
ASISTENCIA EDITORIAL
Célida Duque Molina
César Raúl González Bonilla
Héctor G. Aguirre Gas Petróleos Mexicanos César Athié Gutiérrez Secretaría de Salud
ISSN-e 2448-5667
EDITORES EMÉRITOS
Mauro Eduardo Berta Ramasko
Alberto Lifshitz Guinzberg
Octavio Amancio Chassin Secretaría de Salud
Roberto Arenas Guzmán Secretaría de Salud
Eduardo Ferat Osorio María del Rosario Niebla Fuentes Carlos Francisco Vázquez Rodríguez Niels Agustín Hansen Wacher Rodarte Alejandro Moctezuma Paz
DIVISIÓN DE INVESTIGACIÓN CLÍNICA
Colegio de Medicina Interna de México Javier Santacruz Varela Facultad de Medicina UNAM Carlos Viesca Treviño
REVISTA MÉDICA DEL INSTITUTO MEXICANO DEL SEGURO SOCIAL es una publicación oficial de la Dirección de Prestaciones Médicas. Publicación bimestral editada por la Coordinación de Investigación en Salud. Oficinas Administrativas: Centro Médico Nacional Siglo XXI, Av. Cuauhtémoc 330, Col. Doctores, Deleg. Cuauhtémoc, 06725 Ciudad de México, México. La Revista Médica del Instituto Mexicano del Seguro Social está incluida en los índices MEDLINE, PubMed, Scopus, PERIÓDICA, Imbiomed, MEDIGRAPHIC, MedicLatina, EMBASE, Redalyc. Número de Certificado de Reserva de Derechos al Uso Exclusivo de Título: 042017-053013465500-203, otorga- do por el Instituto Nacional del Derecho de Autor. Número de Certificado de Licitud de Título: 2000. Número de Certificado de Licitud de Contenido: 1244. D.R.
Francisco Espinosa Larrañaga Juan Manuel Sauceda García
TITULAR DE LA COORDINACIÓN DE INVESTIGACIÓN EN SALUD
España Carlos Campillo Artero Finlandia Jaakko Tuomilehto Inglaterra Graham R. V. Hughes Uruguay Blanca Stéffano de Perdomo
Zoé Alejandro Robledo Aburto
Australia Paul Z. Zimmet Colombia Hugo Castaño Ahumada Estados Unidos Jaime HoracioErloHoracioDavisonJinichBrookRothToledoPereyra
vol. 60 núm 5 septiembre-octubre 2022
COMITÉ EDITORIAL INTERNACIONAL
Academia Mexicana de Historia de la Medicina Miguel Ángel Villasis Keever Instituto Mexicano del Seguro Social
Mylene Araiza Márquez
DIRECTOR GENERAL
EDITOR
DIRECTORA DE PRESTACIONES MÉDICAS
Adrián Muñoz Rosales
CUIDADO DE LA EDICIÓN Iván Álvarez Hernández Omar G. Vivas Medrano
La yerba mate como fuente segura de polifenoles durante la lactancia humana Yerba mate as a safe polyphenolic source during human lactation
485
Original contributions
Respuesta a la Revisión metodológica del artículo “Características clínicas asociadas a mortalidad por COVID-19 en cuidados intensivos”
Reinserción laboral posterior a diagnóstico y tratamiento del cáncer de mama
Martha Patricia MorenoHernández, David Alejandro Cabrera-Gaytán, Porfirio Felipe Hernández-Bautista
Methodological review of the article “Clinical characteristics related to mortality by COVID-19 in intensive care”
Aportaciones originales
503
Time of care and its impact in the evolution of laryngeal cancer Irma Yolanda Castillo-López, Luis JulioYasmínHumberto-Govea-Camacho,GracielaGutiérrez-Gallo,CésarPalacios-López
Supervivencia en pacientes pediátricos con neumonía en enfermedad por coronavirus 2019
Letters to the editor
480
In this issue
Patrón de sensibilidad de E. coli en el Centro Médico Nacional del Bajío
Sensitivity pattern of E. coli at the Bajío National Medical Center Jonathan Esaú Hernández-Herrera, Guillermo Sánchez-Pichardo, Derión Sorokto Tsaraí CastruitaTorres, Adriana Iriancid GonzálezJuanMayraTeresaEliaPeredo,Acevedo-García,AndreaDíaz-Murillo,GuadalupeBarrientos-Rodríguez,ManuelCisneros-Carrasco
483
517
Editorial Editorial
Por: David Alfaro Siqueiros
En este número
Josué Israel López-Valdés
Returning to work after diagnosis and treatment of breast cancer Natalia CamejoGabrielDahianaNoraAnaCeciliaMartínez,Castillo-Leska,LauraHernández-Ibero,AmeliaArtagaveytia-Cóppola,LourdesAmarillo-Hernández,DavidKrygier-Waltier
Depression, anxiety and quality of life in pediatric patients with leukemia Elba Nelly Cano-Vázquez, Ángeles Abigail Galmich-Gómez, Polette Alejandra SotoFlores, Luis Eduardo Gutiérrez-Chablé, Daniel Alejandro Ochoa-Fuentes, Irma Beatriz Gónzalez-Merino, Máximo Alejandro García-Flores, Socorro Méndez-Martínez
Survival in pediatric patients with pneumonia in coronavirus disease 2019
Serenity and objectivity in the face of severe childhood hepatitis: the diagnostic challenge
El tiempo de atención y su impacto en la evolución del cáncer laríngeo
Revisión metodológica del artículo “Características clínicas asociadas a mortalidad por COVID-19 en cuidados intensivos”
Cartas al editor
487
495
524
Aportaciones tiempo atención su impacto originales laríngeo Nelly Cano-Vázquez et al. Anestesia multimodal en paciente con reporte
Depresión, ansiedad y calidad de vida en pacientes pediátricos con leucemia
Enportada: Apología de la futura victoria de la ciencia médica contra el cáncer
La imagen
511
Efrén Murillo-Zamora, Alicia Jiménez-Álvarez
Johan Alexander Azañero-Haro
Ana Verónica Scotta, Mariela Valentina Cortez, Luciana Orosz, Agustín Ramiro Miranda, Elio Andrés Soria
Serenidad y objetividad ante la hepatitis grave infantil: el reto diagnóstico
Answer to the Methodological review of the article “Clinical characteristics related to mortality by COVID-19 in intensive care”
563
540
Obesidad, ERC y género en el riesgo de mortalidad hospitalaria a 30 días en adultos con COVID-19 Obesity, CKD and gender on the 30-day in-hospital mortality risk in adults with COVID-19 Efrén Murillo-Zamora, Carlos M. HernándezSuárez, José Guzmán-Esquivel, Iván HossanaMaríaJoséDelgado-Enciso,AlejandroGuzmán-Solórzano,R.Ochoa-Castro,García-García
Disnatremias y su asociación con morbimortalidad en pacientes con COVID-19 Dysnatremias and their association with morbidity and mortality in patients with COVIDFrancisco19Javier Núñez-Martínez, Karla Orozco-Juárez, Alejandro de Jesús Chávez-Lárraga, Jorge Isaac VelascoSantos
Artículos de revisión Review articles
556
Estrés, ansiedad y depresión en trabajadores de salud durante la pandemia por COVID-19 Stress, anxiety, and depression in health workers during the COVID-19 pandemic Abihai Lucas-Hernández, Viviana del Rosario González-Rodríguez, Alejandra LópezFlores, Ashuin Kammar-García, Javier Mancilla-Galindo, Olga VeraLastra, José Luis Jiménez-López, Ana Lilia Peralta Amaro
569
Casos clínicos Clinical cases
577
Combinación de terapias modifica doras en atrofia muscular espinal tipo 2 Combination of modifying therapies in type 2 spinal muscular atrophy María Elena Meza-Cano, Verónica MartínezDávila584
Anestesia multimodal en paciente con enfermedad de Graves y tirotoxicosis: reporte de caso Multimodal anesthesia in a patient with Graves’ disease and thyrotoxicosis: a case report María José Pagán-Rappo, Claudia Estephania Jurado-Fernández de Lara, Olga Castro-Sánchez, Karen Yarivani Carpio-Vargas, Karla Itzel Gutiérrez-Riveroll
Vólvulo cecal: un caso y revisión de la literatura Cecal volvulus: one case and literature review
José Francisco Camacho-Aguilera, Antonio Calderón-Vieyra
Competencia comunicativa de médicos familiares en una unidad de medicina familiar Communicative competence in family physicians in a family medicine unit Vanessa Isela Bermúdez-Villalpando, Hilda Jacqueline González-Limón, Linda Crystal Vidal-Solórzano
Citocinas proinflamatorias en el síndrome de ovario poliquístico Proinflammatory cytokines in polycystic ovarian syndrome Manuel Ramón García-Sáenz, Aldo Ferreira-Hermosillo, Miry Lobaton-Ginsberg
Compromiso laboral y síndrome de burnout en un segundo nivel duran- te pandemia por COVID en México, 2021 Work engagement and burnout syn- drome in a secondary care level dur- ing the COVID pandemic in Mexico, 2021 Jaqueline Rosas-Paez, Juan CasillasEspriella, Juan Carlos TinajeroSánchez, Víctor Daniel Martínez-Enciso
548
591
533
M CARMEN RODRÍGUEZ OTERO
GUÍA DE USO MENDELEYDE
Contenido 1. ¿QUÉ ES MENDELEY?................................................................4 2. ACCESO A MENDELEY Y CREACIÓN DE UNA CUENTA.....................4 3. VERSIÓN LOCAL (MENDELEY DESKTOP)......................................8 4. AÑADIR REFERENCIAS..............................................................9 4.1. Manualmente 9 4.2. Añadiendo directamente documentos desde archivos PDF...................................10 4.3. Importando desde otros gestores bibliográficos....................................................14 4.4. Importando resultados desde Bases de datos........................................................15 4.5. Importando desde otros sitios Web.......................................................................17 4.6. SINCRONIZAR. (Synchronize Library)......................................................................20 4.7. Sincronizando desde cuentas de CiteUlike y Zotero 21 4.8. Añadiendo referencias desde cuentas de otros usuarios de Mendeley.................25 5. EXPORTAR REFERENCIAS.........................................................26 6. TRABAJAR CON DOCUMENTOS Y REFERENCIAS..........................27 6.1. Leídos/no Leídos y favoritos 27 6.2. Ordenar las referencias..........................................................................................28 6.3. Depurar nombres de autor, etiquetas o publicaciones duplicadas. 28 6.4. Etiquetar y editar varios documentos a la vez. 29 6.5. Buscar.....................................................................................................................29 6.6. Realizar anotaciones en los PDFs 30 7. ELIMINAR DUPLICADOS...........................................................32 7.1. Unir duplicados.......................................................................................................34 7.2. Duplicados incorrectos 35 7.3. Unión manual de duplicados..................................................................................36 7.4. ¿Qué pasa si nos equivocamos?.............................................................................36 8. ORGANIZAR FICHEROS............................................................37 9. CITAR REFERENCIAS Y FORMATEAR EL MANUSCRITO 38 9.1. Estilos de cita bibliográfica.....................................................................................38 9.2. Generar Bibliografías, insertar citas y formatear un manuscrito...........................39 10. COMPARTIR DOCUMENTOS Y REFERENCIAS...............................42 9.3. GRUPOS 42 11. VERSIÓN WEB........................................................................47 12. BIBLIOGRAFÍA........................................................................51 Página 2 de 52
13. ANEXOS: VIDEOS Y PRESENTACIONES 51