RECENTLY FEATURED PUBLICATIONS IN NEURO ONCOLOGY

Kortz MW, Lillehei KO. Insular Cortex. 2022 May 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 34033368.

Stortz E, Turin C, Lillehei K, Catel C, Damek D, Wierman, M. ODP333 Mucosal-Associated Lymphoid Tissue Lymphoma: a Rare Condition in the Differential Diagnosis of a Parasellar Mass, Journal of the Endocrine Society, Volume 6, Issue Supplement_1, November-December 2022, Page A501, https://doi.org/10.1210/jendso/bvac150.1042

Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D’Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW; GLASS Consortium. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. 2022 Jun 9;185(12):2184-2199.e16. doi: 10.1016/j.cell.2022.04.038. Epub 2022 May 31. PMID: 35649412; PMCID: PMC9189056.

Au TH, Willis C, Reblin M, Peters KB, Nghiemphu PL, Taylor JW, Colman H, Cohen AL, Ormond DR, Neil EC, Chakravarti A, Willmarth N, Balajonda BC, Menon J, Ma J, Bauer H, Iacob E, Nelson RS, Tan MS, Singh P, Marshall A, Korytowsky B, Stenehjem D, Brixner D. Caregiver survey in GBM focused on cognitive dysfunction: Development and results from a multicenter stud. Future Oncology. In press.

Kleinschmidt-DeMasters BK, Ormond DR. Leptomeningeal and Extraneural Metastases in Adult High-Grade Gliomas. J Neuropathol Exp Neurol. 2023 Jan 13;. doi: 10.1093/jnen/nlac126. [Epub ahead of print] PubMed PMID: 36637258.

Ung T, Ormond DR. Endoscopic approaches for biopsy of a pineal region tumor. CNS Nexus. https://www.cns. org/nexus-author-detail?formId=726f54c9-ad21-4ba6-a4c3-54c991382190&uvId=9e1bc9ca-2e24-433c-90b91f69a404ddcf&userId=d4f8588b-8180-4e83-a2b4-28b9c906d5c3.

Travers S, Ormond DR. Telovelar approach for resection of a fourth ventricular ependymoma. CNS Nexus, August 2022. https://www.cns.org/nexus/case/detail/23738905-6c07-4a94-a496-bd25fde0e37d

Travers, S, Lillehei KO, Ormond DR. Endoscopic transnasal resection of large clival chordoma. CNS Nexus, August 2022. https://www.cns.org/nexus/case/detail/19bb37f1-dcb8-4920-b9ed-9175b7c45326

Zhou W, Lovasz D, Zizzo Z, He Q, Coughlan C, Kowalski RG, Kennedy PGE, Graner A, Lillehei KO, Ormond DR, Youssef AS, Graner MW, Yu X. Phenotype and neuronal cytotoxic function of glioblastoma extracellular vesicles. Biomedicines. 2022;10(11):2718; https://doi.org/10.3390/biomedicines10112718.

Tatman PD, Wroblewski TH, Fringuello AR, Scherer SS, Foreman WB, Damek DM, Youssef AS, Lillehei KO, Jenson R, Graner MW, Ormond DR. High-throughput screening of epigenetic inhibitors in meningiomas identifies HDAC, G9a, and Jumonji-domain inhibition as potential therapies. J Neurol Surg B Skull Base. DOI: 10.1055/a-1885-1257.

Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW; GLASS Consortium. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. 2022 Jun 9;185(12):2184-2199.e16. doi: 10.1016/j.cell.2022.04.038. Epub 2022 May 31.PMID: 35649412

Germano IM, Johnson DR, Patrick HH, Goodman AL, Ziu M, Ormond DR, Olson JJ. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Management of Progressive Glioblastoma in Adults: Update of the 2014 Guidelines. Neurosurgery. 2022 May 1;90(5):e112-e115. doi: 10.1227/ neu.0000000000001903.

Belanger K, Ung TH, Damek D, Lillehei KO, Ormond DR. Concomitant Temozolomide Plus Radiotherapy for HighGrade and Recurrent Meningioma: A Retrospective Chart Review. BMC Cancer. 2022 Apr 7;22(1):367. doi: 10.1186/ s12885-022-09340-7. PubMed PMID: 35392834; PubMed Central PMCID: PMC8988385.

Tatman PD, Wroblewski TH, Fringuello AR, Scherer SR, Foreman WB, Damek DM, Lillehei KO, Jensen RL, Youssef AS, Ormond DR, Graner MW. Targeting DNA Methyl Transferases with Decitabine in Cultured Meningiomas. World Neurosurg. 2022 Mar 3:S1878-8750(22)00255-8. doi: 10.1016/j.wneu.2022.02.108. Online ahead of print.

Germano IM, Ziu M, Wen P, Ormond DR, Olson JJ. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines Update on the Role of Cytotoxic Chemotherapy and Other Cytotoxic Therapies in the Management of Progressive Glioblastoma in Adults. Journal of Neuro-Oncology. J Neurooncol. 2022 Feb 23;. doi: 10.1007/s11060-021-03900-w. [Epub ahead of print] Review. PubMed PMID: 35195819.

Au TH, Willis C, Reblin M, Peters KB, Nghiemphu PL, Taylor JW, Colman H, Cohen AL, Ormond DR, Chakravarti A, Willmarth N, Menon J, Ma J, Bauer H, Watanabe AH, Ulrich CM, Singh P, Marshall A, Korytowsky B, Stenehjem D, Brixner D. Correction to: Caregiver burden by treatment and clinical characteristics of patients with glioblastoma. Support Care Cancer. 2022 Feb;30(2):1377-1378. doi: 10.1007/s00520-021-06691-y. PubMed PMID: 34792647.

One of the many conditions with which neurosurgical spine providers are often called to treat involve Cerebral Spinal Fluid leaks. One such patient is Elaine Restauri, recently featured in the monthly published CU newsletter. As the CU story states, Elaine is a mother of three who lost her husband when her youngest daughter was only six months old, she raised her family in the Pittsburgh area, making a life for herself as a graphic artist. In 2009, Elaine relocated to Colorado to be with her three daughters. She is an independent and happy woman who loved gardening and painting with watercolors and acrylics.

Her problems began in 2012. After returning to Denver from an international flight, her head began to hurt in a way she could never have ever imagined. She initially assumed she was dehydrated, jet lagged or had a sinus infection. After six weeks of horrific head pain, she sought medical help and was given an initial diagnosis of meningitis before physicians suspected a rare CSF spinal canal leak and used a procedure using her own blood to patch it. This worked temporarily, but she had to seek treatment again in 2019.

By the summer of 2021, her symptoms were so awful that she spent many of her days in bed. She experienced nausea, vomiting and vertigo in addition to head pain. At that point she was referred to our “CSF Dynamics Clinic,” undergoing definitive spinal surgery by Neurosurgeon, Dr. Peter Lennarson. This resulted in a dramatic cure. To hear more about this story click here:

LINK to STORY: https://www.uchealth.org/today/new-anschutz-medical-campus-clinic-treatment-spontaneous-csf-leaks/

Dr. Peter Lennarson Receives Special Recognition

Physicians often receive awards, accolades and kind notes of gratitude from their patients, but recently, Dr. Peter Lennarson received a very special patient letter. “What does one say or do for the man that saved your life? I don’t think there are powerful enough words in the English language to express the amount of gratitude and appreciation we have for you…”

“You saved my life on the 9 year anniversary of my injury!... Please let the people in your life know that you saved mine!...”

…”We are sure you probably don’t take enough credit for the absolutely amazing surgeon you are. Even though you might say you were just doing your job, you made a difference to us!”

“We can only imagine that, because you are such an awesome neurosurgeon, you get many “thank you’s,” but THANK YOU for not just taking the time to make me well … but to make me WHOLE.” Michelle & Jim R.

Chatain GP, Kortz MW, Serva S, Shrestha K, Hosokawa P, Ung TH, Finn M. Long-term Neurologic Outcome After Spinal Ependymoma Resection With Multimodal Intraoperative Electrophysiological Recording: Cohort Study and Review of the Literature. Neurospine. 2022 Mar;19(1):118-132. doi: 10.14245/ns.2143200.600. Epub 2022 Mar 31. PMID: 35378586; PMCID: PMC8987544.

Chatain GP, Shrestha K, Kortz MW, Serva S, Hosokawa P, Ward RC, Sethi A, Finn M. Impact of Surgical Timing on Neurological Outcomes for Spinal Arachnoid Cyst: A Single Institution Series. Neurospine. 2022 Jun;19(2):453-462. doi: 10.14245/ns.2244130.065. Epub 2022 Jun 23. PMID: 35793936; PMCID: PMC9260545.

Chatain GP, Chee Keanu, Finn M. Review of transoral odontoidectomy. Where do we stand? Technical note and a singlecenter experience. Interdisciplinary Neurosurgery 2022 Sep; 29(101549

Yang JH, Tuano KR, Finn M, Weyant M, Chong TW, Mathes DW. Successful repair of chronic esophageal perforation