EVALUATION OF THE IMMUNE RESPONSE
3.6 Checklist for post-vaccination monitoring of immunity – Obtain evidence of vaccine efficacy and, if possible, post-vaccination sera from vaccine manufacturers’ potency and batch release tests.
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– Carry out a pre-purchase study of elicited immunity in a small group of local animals and afterwards in a cohort of animals in the field when vaccination has been implemented. – Monitor levels of regional and overall population immunity to determine if vaccination has been implemented properly and if protection can be expected.
– Establish serology thresholds taking account of the impact of variability in the immune responses of animals, in the reproducibility of tests and in the antigenic properties of vaccine, field and test viruses.
Foot and mouth disease vaccination and post-vaccination monitoring. Guidelines