This study aims to combine passive design approach and energy conservation into a hybrid set of strategies for designing low energy climate responsive urban in-fill homes in three major Vietnamese cities: Ha Noi, Da Nang and Ho Chi Minh City. As part of the study, a series of literature reviews on both previous research and construction projects done in similar climates as those of Vietnam are conducted. They serve as the basis for the establishment of this illustrated set of design strategies. One potential strategy, selected by the author, is modeled to simulate its overall energy effectiveness. The result of this simulation not only and to reaffirm the validity of the entire solution set but also indicate the applicability and the effectiveness of certain strategies in achieving thermal comfort, and energy efficiency in tropical climates such as Vietnam. This study stresses the importance of integrating design concepts with climate analysis early in the design process.