Bone Marrow and Stem Cell Transplantation | Dr. David Greene Arizona

BONE MARROW AND STEM CELL TRANSPLANTATION DR. DAVID GREENE ARIZONA

WHAT ARE BLOOD-FORMING STEM CELLS? Blood cells are made in your bone marrow, a spongy tissue located inside the bones. This tissue contains parent cells called stem cells.

These blood-forming stem cells make copies of themselves and produce all three types of blood cells – red blood cells, white blood cells and platelets

WHAT IS A BONE MARROW TRANSPLANT? A one marrow transplant (BMT), also called a stem cell transplant, is a standard treatment option for many patients with certain life-threatening blood, immune system or genetic disorders. This treatment replaces your unhealthy blood-forming stem cells with healthy ones b

WHAT IS A REDUCED-INTENSITY TRANSPLANT? Reduced-intensity transplants use less intense treatment to prepare for transplantation than that used with higher dose "standard" regimens. They are sometimes also called non-myeloablative transplants or "mini"-transplants

What are the different types of transplants?

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• Autologous transplants use a patient's own blood-forming stem cells. These are collected from the patient's marrow or blood and frozen for later use. Autologous transplants are often not an option for patients with bone marrow failure diseases

Allogeneic transplants use cells from a healthy donor. The donor's tissue type must suitably match the patient's type. A donor can be either related or unrelated. Related donors are usually a brother or sister

STEM CELL TRANSPLANTATION FOR MYELODYSPLASTIC SYNDROMES Whether patients with MDS should undergo Hematopoietic stem cell transplant (HSCT) as soon as their MDS is diagnosed or wait for months or even years depends on their IPSS score

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