Bioengineering and Biotechnology Courses

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Contents Biosignals and Systems ................................................3 Biomechanics ..............................................................7 Bio MEMS, NEMS, & Materials..................................10 Biomedical Imaging ..................................................14 Page 3

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Biophysics ..................................................................16 Biotechnology............................................................18 General Textbooks ....................................................22

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Biosignals and Systems From Esteemed CRC Press Author Robert B. Northrop University of Connecticut, Storrs, USA

Updated Edition of a Bestseller

Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation Second Edition Series: Biomedical Engineering

Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation, Second Edition helps biomedical engineers understand the basic analog electronic circuits used for signal conditioning in biomedical instruments. It explains the function and design of signal conditioning systems using analog ICs—the circuits that enable ECG, EEG, EMG, ERG, tomographic images, biochemical spectrograms, and other crucial medical applications.

Pedagogical Features

This book demonstrates how op amps are the keystone of modern analog signal conditioning system design and illustrates how they can be used to build instrumentation amplifiers, active filters, and many other biomedical instrumentation systems and subsystems. It introduces the mathematical tools used to describe noise and its propagation through linear systems, and it looks at how signal-to-noise ratios can be improved by signal averaging and linear filtering.

Sources and Properties of Biomedical Signals Properties and Models of Semiconductor Devices Used in Analog Electronic Systems The Differential Amplifier General Properties of Electronic, Single-Loop Feedback Systems Feedback, Frequency Response, and Amplifier Stability Operational Amplifiers and Comparators Introduction to Analog Active Filters Instrumentation and Medical Isolation Amplifiers Noise and the Design of Low-Noise Signal Conditioning Systems for Biomedical Applications Digital Interfaces Modulation and Demodulation of Biomedical Signals Power Amplifiers and Their Applications in Biomedicine Wireless Patient Monitoring RFID Tags, GPS Tags, and Ultrasonic Tags Used in Ecological Research Examples of Special Analog Circuits and Systems Used in Biomedical Instrumentation Appendix Glossary Bibliography and Recommended Reading

• Analyzes the properties of photonic sensors and emitters and the circuits that power them • Details the design of instrumentation amplifiers and medical isolation amplifiers • Considers the modulation and demodulation of biomedical signals • Examines analog power amplifiers, including power op amps and class D (switched) PAs • Describes wireless patient monitoring, including Wi-Fi and Bluetooth communication protocols • Explores RFID, GPS, and ultrasonic tags and the design of fractal antennas • Addresses special analog electronic circuits and systems such as phase-sensitive rectifiers, phase detectors, and IC thermometers By explaining the "building blocks" of biomedical systems, the author illustrates the importance of signal conditioning systems in the devices that gather and monitor patients’ critical medical information. Fully revised and updated, this second edition includes new chapters, a glossary, and new end-of-chapter problems.

• An extensive glossary • End-of-chapter problems and examples that emphasize biomedical electronic applications A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents

Catalog no. K12982, March 2012, 578 pp.

ISBN: 978-1-4398-6669-6, $119.95 / £76.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

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Biosignals and Systems From Esteemed CRC Press Author Robert B. Northrop University of Connecticut, Storrs, USA

Signals and Systems Analysis in Biomedical Engineering Second Edition Series: Biomedical Engineering

The interdisciplinary field of biomedical engineering requires its practitioners to know and master not only engineering skills, but also a diversity of material in the biological sciences.

This text helps biomedical engineering students and professionals strengthen their skills in the network of applied mathematics that ties together these diverse disciplines. Based on the author's 30 years of experience in teaching as well as his personal research on neurosensory systems, this book, now in its second edition, provides a ready source of information on the specialized mathematical techniques most useful in describing and analyzing biomedical signals.

Introduction to Complexity and Complex Systems Written for students and professionals in the fields of biomedical engineering, systems biology, biophysics, and physiology, this unique reference covers complexity issues within living systems. Topics include human responses to coping with complex systems, the Law of Unintended Consequences, the relation of complexity to evolution, the complexity inherent in invertebrate immune systems, and the complexity inherent in economic systems. A comprehensive glossary provides acronyms and terms relating to complex, nonlinear biological systems. Dynamic models and homework questions are also included to further aid in understanding.

Features

Pedagogical Features

• Focuses on the mathematical tools required to analyze and describe the signals and systems found in biomedical engineering • Includes a comprehensive chapter on joint time-frequency analysis of nonstationary biomedical signals, and the use of wavelets in JTFA • Explores the mathematics of tomographic imaging • Describes the analytical signal and the Hilbert transform • Discusses the analysis of nonlinear systems, nonlinear oscillators, and biological clocks • Introduces the analysis of and modeling strategies for complex systems

• Dynamic models for various complex systems • Present-day examples for dealing with complex systems • Homework problems • A glossary

A solutions manual is available upon qualifying course adoption.

Selected Contents Introduction to Biomedical Signals and Systems.

Review of Linear Systems Theory. The Laplace Transform and Its Applications. Fourier Series Analysis of Periodic Signals. The Continuous Fourier Transform. The Discrete Fourier Transform.

Introduction to Joint Time Frequency Analysis of Biomedical Signals. Introduction to the Analysis of Stationary Noise, and Signals Contaminated with Noise. ... Glossary. Appendices. Index.

Catalog no. K10633, March 2010, 654 pp.

ISBN: 978-1-4398-1251-8, $109.95 / £69.99

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A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction to Complexity and Complex Systems. Introduction to Large Linear Systems.

Introduction to Nonlinear Biochemical Systems and Biochemical Oscillators. Modularity, Redundancy, Degeneracy, Pleiotropy and Robustness in Complex Biological Systems. The Evolution of Biological Complexity; Invertebrate Immune Systems. The Complex Adaptive and Innate Human Immune Systems. Complexity in Quasispecies: MicroRNAs. Introduction to Physiological Complexity: Examples of Models of Some Complex Physiological Systems. The Quest for Quantitative Measures of Complexity.

"Irreducible and Specified Complexity" in Living Systems. Introduction to Complexity in Economic Systems. Dealing with Complexity. Appendix.

Bibliography and References. Glossary. Index.

Catalog no. K11775, December 2010, 551 pp.

ISBN: 978-1-4398-3901-0, $87.95 / £56.99 Also available as an eBook

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Biosignals and Systems Biomedical Engineering Principles Second Edition Arthur B. Ritter, Vikki Hazelwood, Antonio Valdevit, and Alfred N. Ascione Praise for the Previous Edition “... not only an in-breadth overview on current BME fields, but also an in-depth analysis of specific selected topics that are supported by appropriate mathematical models, equations, quantitative data charts and tables."

—Biomedical Engineering Online, 2005

“... an excellent textbook for a class. Each chapter contains numerous examples and contains many figures to enhance learning. References and suggestions for further reading are included at the end of each chapter. Problems are included at the end of chapters, where they will best test the student's knowledge.”

—Richard C. Fries, PE, CRE, Baxter Healthcare, Inc., in IEEE Engineering in Medicine and Biology Magazine, December 2006

Integrating engineering, medicine, biology, and physics, this book clearly defines basic principles in image processing and biomechanics, modeling physiological processes, and bioelectric signal analysis to build a solid understanding of devices and designs for improved functioning of the human body.

Pedagogical Features • Extensive examples • In-chapter problems A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction: Modeling of Physiological Processes.

Cell Physiology and Transport. Principles and Biomedical Applications of Hemodynamics. A Systems Approach to Physiology. The Cardiovascular System. Biomedical Signal Processing. Signal Acquisition and Processing.

Techniques for Physiological Signal Processing.

Examples of Physiological Signal Processing.

Principles of Biomechanics. Practical Applications of Biomechanics. Biomaterials. Principles of Biomedical Capstone Design. Unmet Clinical Needs. Entrepreneurship: Reasons why Most Good Designs Never Get to Market. ...

Catalog no. K10621, May 2011, 540 pp.

ISBN: 978-1-4398-1232-7, $104.95 / £66.99 Also available as an eBook

Bestseller

Basic Transport Phenomena in Biomedical Engineering Third Edition Ronald L. Fournier University of Toledo, Ohio, USA

Exploring fundamental engineering and life science principles to uncover key concepts in biomedical engineering transport phenomena, this volume begins with a review of the basics of thermodynamics. It then examines the physical properties of body fluids and the cell membrane before moving on to topics such as properties of blood, solute transport, pharmacokinetic analysis, extracorporeal devices, tissue engineering, and bioartificial organs.

Homework problems provide students the opportunity to explore in greater detail the material covered in each chapter.

Features • Provides an introductory-level text for students in bioengineering, chemical engineering, mechanical engineering, and the life sciences • Presents a basic understanding and the theories of transport in biological systems and then builds on this knowledge base to show real-world applications in the development and design of artificial organs, drug delivery systems, and tissue engineering • Contains an extensive bibliography of the research literature that supports the material in the text Pedagogical Features • Numerous examples with a discussion of the numerical methods used to solve the problems • Many illustrations • End-of-chapter homework problems A solutions manual is available upon qualifying course adoption.

Selected Contents Introduction. A Review of Thermodynamic Concepts. Physical Properties of the Body Fluids and the Cell Membrane. The Physical and Flow Properties of Blood. Solute Transport in Biological Systems. Pharmacokinetic Analysis. Extracorporeal Devices. Tissue Engineering. Bioartificial Organs.

Index.

Catalog no. K11304, August 2011, 483 pp.

ISBN: 978-1-4398-2670-6, $93.95 / £46.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

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Biosignals and Systems

Introduction to Biomedical Engineering Technology Second Edition Laurence Street Rosedale, British Colombia, Canada

Thoroughly revised and updated, this second edition describes current technological devices, the physiological and anatomical basis of their function, their practical applications, and their common locations in hospitals.

• Covers a wider range of devices and includes an expanded section on equipment management • Describes the day-to-day work of biomedical engineering technologists using extensive examples • Provides appendices listing normal medical values, biomedical associations, test equipment manufacturers, helpful Internet resources, and more Pedagogical Features • • • •

Chapter summaries Questions to aid in reader comprehension More than 360 illustrations A 16-page grayscale insert with photographs of real-life equipment problems A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents

Biology for Engineers Arthur T. Johnson University of Maryland, College Park, USA

Introducing the field of biology to today’s engineering students, this entry-level text minimizes unnecessary memorization of connections and classifications and emphasizes concepts, technology, and the utilization of living things. Filled with practical examples, the book discusses biological responses from the perspectives of psychology, human factors, genetics, plant and animal physiology, imaging, control systems, actuary, and medicine. Offering numerous tables of useful information, it covers the scaling of biological responses and attributes as well as different types of applications related to biological systems. Classroom-tested at the University of Maryland, this comprehensive text introduces the concepts and terminology needed to understand more advanced biology literature.

Features • Explores areas in physics, chemistry, mathematics, and engineering relating to biology • Examines the differences between biological engineering and biological science • Includes a chapter on scaling relations showing how size effects other physical characteristics • Surveys a broad range of application areas Pedagogical Features • Questions at the end of each chapter to test comprehension • Practical examples

Introduction. Diagnostic Devices: Part One. Diagnostic Devices: Part Two. Diagnostic Devices: Part Three. Diagnostic Imaging. Treatment Devices: Part One. Treatment Devices: Part Two. Treatment Devices: Part Three. Biomedical Engineering Technologist (BMET) Work. Testers and Tools. Batteries, Radiation, and Computers.

Technology Management. Appendix A: Normal Values. Appendix B: Regulations and Standards.

Appendix C: Biomedical Engineering Technology Programs in the United States and Canada.

Appendix D: Biomedical Associations. Appendix E: Devices and Manufacturers. Appendix F: Test Equipment Manufacturers. Appendix G: Bibliography and Internet Resources. Index.

Introduction: Introduction. Principles from the Sciences: Principles of Physics. Principles of Chemistry. Principles of Mathematics and Engineering Sciences. Principles of Biology.

Responses of Living Systems: Biological Responses in Context. Scaling Factors: Allometric Relationships from Evolutionary Pressure. Utilizing Living Systems: Systems Approach. Appendices.

References. Index.

Catalog no. K12781, October 2011, 391 pp.

ISBN: 978-1-4398-6058-8, $93.95 / £59.99 Also available as an eBook

Catalog no. 77635, September 2010, 775 pp.

ISBN: 978-1-4200-7763-6, $109.95 / £69.99 Also available as an eBook

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A solutions manual is available upon qualifying course adoption.

Selected Contents

Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

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Biomechanics

Forthcoming

Fundamentals of Biomechanics Ronald L. Huston University of Cincinnati, Ohio, USA

Biomechanics is a fundamental topic of study that employs the principles of mechanics applied to human systems and organs. This textbook provides a comprehensive survey of this increasingly important subject. After a review of terminology, a summary of human anatomy, and a presentation of anthropoTissue Biomechanics metric data, the text discusses methods for biomeHard and Soft Tissue chanical analyses including essential mathematics, Bones mechanics, and modeling techniques. It then covBone Cells and Microstructure... ers tissue biomechanics, kinematics and dynamics Kinematical Preliminaries: Fundamental of human body models, and applications such as Equations lifting, walking, swimming, and accident victim Points, Particles, and Bodies simulation. Each chapter contains reference lists for Particle, Position, and Reference Frames more in-depth study and problems sets with soluParticle Velocity... tions.

Kinematic Preliminaries: Inertia Force Pedagogical Features Considerations Applied Forces and Inertia Forces • An extensive glossary Mass Center • Numerous examples, illustrations, and tables Equivalent Inertia Force Systems...

• End-of-chapter problems to test assimilation Human Body Inertia Properties Second Moment Vectors, Moments, and Products A solutions manual and figure slides are available of Inertia upon qualifying course adoption.

Inertia Dyadics Selected Contents Sets of Particles...

Kinematics of Human Body Models Introduction Notation, Degrees of Freedom, and Coordinates Principal Areas of Biomechanics Angular Velocities Approach in This Book Generalized Coordinates Review of Human Anatomy and Some Basic Partial Angular Velocities...

Terminology Kinetics of Human Body Models Gross (Whole-Body) Modeling Applied (Active) and Inertia (Passive) Forces Position and Direction Terminology...

Generalized Forces Methods of Analysis I: Review of Vectors, Generalized Applied (Active) Forces on a Human Dyadics, Matrices, and Determinants Body Model...

Vectors Dynamics of Human Body Models Vector Algebra: Addition and Multiplication by Kane's Equations Scalars...

Generalized Forces for a Human Body Model Methods of Analysis II: Forces and Force Dynamical Equations...

Systems Numerical Methods Forces: Vector Representations Governing Equations Moments of Forces Numerical Development of the Governing Moments of Forces about Lines...

Equations...

Methods of Analysis III: Mechanics of Materials Simulations and Applications Concepts of Stress Review of Human Modeling for Dynamic Concepts of Strain Simulation Principal Values of Stress and Strains...

A Human Body in Free-Space: A "Spacewalk" Methods of Analysis IV: Modeling of Biosystems A Simple Weight Lift...

Multibody (Lumped Mass) Systems Appendix: Anthropometric Data Tables Lower Body Arrays Whole Body, Head/Neck, and Hand Models Catalog no. K14776, May 2013, c. 512 pp.

Gross-Motion Modeling of Flexible Systems...

ISBN: 978-1-4665-1037-1, $99.95 / £63.99 For more information and complete contents, visit www.crctextbooks.com

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Biomechanics Biofluid Mechanics The Human Circulation, Second Edition Krishnan B. Chandran, Ajit P. Yoganathan, and Stanley E. Rittgers “... the book provides a good platform in fluid mechanics prior to progressing to the physiological applications which make it an appropriate textbook for BME students."

—Professor Tim McGloughlin, Centre for Applied Biomedical Engineering Research and Department of Mechanical Aeronautical and Biomedical Engineering, University of Limerick

This classroom-tested text teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition includes improved figures, additional examples, and more problems at the end of each chapter.

It also presents a new chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas.

• Provides a classroom-tested textbook for a first course on fluid mechanics in human circulation, focusing on the heart and major arteries • Reviews fluid and solid mechanics and normal cardiovascular physiology • Explains how to model steady and unsteady flows • Evaluates the design and development of artificial heart valves, stent implants, and vascular grafts • Describes various considerations and approaches involved in the computational modeling of cardiovascular diseases and therapies Pedagogical Features • End-of-chapter problems • Examples • Numerous figures throughout, selected from the publications of many eminent researchers A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents FLUID AND SOLID MECHANICS AND CARDIOVASCULAR PHYSIOLOGY Fundamentals of Fluid Mechanics Introduction Intrinsic Fluid Properties Hydrostatics...

Introduction to Solid Mechanics Introduction to Mechanics of Materials Analysis of Thin-Walled Cylindrical Tubes...

Cardiovascular Physiology Introduction Heart

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Cardiac Valves...

BIOMECHANICS OF THE HUMAN CIRCULATION Rheology of Blood and Vascular Mechanics Rheology of Blood Summary...

Static and Steady Flow Models Introduction Hydrostatics in the Circulation Applications of the Bernoulli Equation Rigid Tube Flow Models...

Unsteady Flow and Nonuniform Geometric Models Introduction Windkessel Models for the Human Circulation Continuum Models for Pulsatile Flow Dynamics...

Native Heart Valves Introduction Aortic and Pulmonary Valves Mitral and Tricuspid Valves CARDIOVASCULAR IMPLANTS, BIOMECHANICAL MEASUREMENTS, AND COMPUTATIONAL SIMULATIONS Prosthetic Heart Valve Dynamics Introduction Brief History of Heart Valve Prostheses Hemodynamic Assessment of Prosthetic Heart Valves...

Vascular Therapeutic Techniques Vascular Graft Implants Arteriovenous Fistulas Types of Vascular Graft Materials Used...

Fluid Dynamic Measurement Techniques Introduction Blood Pressure Measurement Blood Flow Measurement Impedance Measurement...

Computational Fluid Dynamic Analysis of the Human Circulation Introduction Computational Fluid Dynamic (CFD) Analysis Techniques ...

Index Catalog no. K12006, February 2012, 451 pp.

ISBN: 978-1-4398-4516-5, $104.95 / £66.99 Also available as an eBook

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Biomechanics Biomechanics of the Upper Limbs Mechanics, Modeling and Musculoskeletal Injuries, Second Edition

Biomechanics and Exercise Physiology Quantitative Modeling

Andris Freivalds

Arthur T. Johnson

The Pennsylvania State University, University Park, USA

University of Maryland, College Park, USA

Over the past two decades, the growth in computer-related jobs has led to considerable increase in the number of work-related musculoskeletal disorders in the upper limbs. Biomechanics of the Upper Limbs: Mechanics, Modeling and Musculoskeletal Injuries, Second Edition offers vital information and tools to improve analysis of external forces and their effects on the human body. This can help ergonomists better understand job stressors and the role they play in the development of disorders, enabling them to modify the work environment and educate practitioners to better control harmful situations. Now in its second edition, this comprehensive text is expanded to include recent findings regarding job stressors and a variety of ergonomic solutions. It provides research on the biomechanics of the upper limbs and the mechanics of neuromuscular systems. The book also covers risk factors for various disorders and tools used to identify their causes.

Using numerous worked examples to demonstrate what and when to calculate, this text covers more than just the fundamentals of exercise physiology, it demonstrates the vast amount of physiological material that can be quantitatively predicted and describes how to translate this information into applications. The book examines the energetics of exercise, biomechanics, circulation, respiration, and thermoregulation, and includes numerical examples and homework problems. With an emphasis on quantitative description, it includes tables and illustrations that make this book helpful for estimating magnitudes, determining trends, and illustrating concepts.

Pedagogical Features • Numerous examples in each chapter • Downloadable PowerPoint® slides, sample exams, and other background material on a supporting website • End-of-chapter references to enhance further study A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction to Biomechanics. Structure of the Musculoskeletal System. Neuromuscular Physiology and Motor Control. Modeling of Muscle Mechanics. Models of the Upper Limbs.

Musculoskeletal Disorders and Risk Factors.

Instrumentation. Job and Worksite Analysis.

Hand Tools. The Office Environment.

Catalog no. 91190, February 2011, 564 pp.

ISBN: 978-1-4200-9119-9, $125.95 / £79.99 Also available as an eBook

Catalog no. DK5813, March 2007, 688 pp.

ISBN: 978-1-57444-906-8, $145.95 / £93.00

Biofluid Dynamics Principles and Selected Applications Clement Kleinstreuer North Carolina State University, Raleigh, USA

Biofluid Dynamics builds a solid understanding of medical implants and devices from a bioengineering standpoint. The text features worked examples and mathematical appendices; exercises and project assignments to stimulate critical thinking and build problem-solving skills; numerous illustrations, including a 16-page color insert; computer simulations of biofluid dynamics processes and medical device operations; tools for solving basic biofluid problems; and a glossary. The text can be used as a primary selection for a comprehensive course or for a two-course sequence or as a reference for professionals.

A solutions manual is available upon qualifying course adoption.

Catalog no. 2221, April 2006, 528 pp.

ISBN: 978-0-8493-2221-1, $119.95 / £77.99

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Bio MEMS, NEMS & Materials Textbooks for Your Biomaterials Lectures and Lab Courses An Introduction to Biomaterials Second Edition Edited by

Jeffrey O. Hollinger Carnegie Mellon University, Pittsburgh, Pennsylvania, USA Series: Biomedical Engineering

The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date educational framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living system into which it is implanted.

Features • Covers wound healing biology and host response to implanted biomaterials • Examines the regulatory process, including standardized product testing • Reviews the innovativeness of biomaterials, with inventorship and patents in mind • Considers experimental design, basic scientific methods, and statistics Pedagogical Features • Numerous examples • End-of-chapter questions and answers • Extensive references for further study An instructor's manual and figure slides are available upon qualifying course adoption.

Selected Contents Consensus Definitions, Fundamental Concepts, and a Standardized Approach to Applied Biomaterials Sciences. Biology, Biomechanics, Biomaterial Interactions: Wound Healing Biology.

Biology, Biomechanics, Biomaterial Interactions: Cellular Mechanics. Biology, Biomechanics, Biomaterial Interactions: Materials–Host Interactions. Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Standardized Materials Testing. Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Statistics. Biomaterials Compositions. Biomaterials Applications. Index Catalog no. K10637, November 2011, 644 pp.

ISBN: 978-1-4398-1256-3, $119.95 / £49.99 Also available as an eBook

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A Laboratory Course in Biomaterials Wujing Xian University of Illinois at Urbana-Champaign, USA

A teaching tool for instructors in biomaterials and bioengineering, this volume is a comprehensive laboratory textbook. It trains readers in laboratory skills, data analysis, problem solving, and scientific writing. It integrates a variety of principles that include materials science, chemistry, biochemistry, molecular and cell biology, and engineering.

Providing detailed descriptions, explanations, and illustrations of experiments, the text also includes a series of questions and answers at the end of each chapter to clarify concepts. Many of the experiments presented are adapted from research papers to reflect the recent progress in biomaterials and bioengineering.

Pedagogical Features • Detailed, step-by-step descriptions of lab procedures and explanations for the underlying principles • User-friendly graphic illustrations for the experiments • End-of-chapter questions and answers to clarify concepts and induce critical thinking • Text boxes with in-depth information, case studies, and lab tips • Information on equipment, reagents, and supplies for instructors Selected Contents Basic Laboratory Skills Module I: Drug Delivery: Controlled Release of Encapsulated Protein from PLGA Microspheres Module II: Natural Biomaterials: Collagen and Chitosan Basic Laboratory Skills II: Cell Culture and Microscopy Module III: Biocompatibility Testing: Cytotoxicity and Adhesion Module IV: Tissue Engineering: Organotypic Cultures of Skin Equivalents Module V: Bioceramics: Porous Hydroxyapatite Composite Appendix: Answers Index Catalog no. 75829, June 2009, 216 pp., Soft Cover ISBN: 978-1-4200-7582-3, $67.95 / £43.99

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Bio MEMS, NEMS & Materials Introduction to BioMEMS A Laboratory Course in Tissue Engineering Melissa Kurtis Micou and Dawn M. Kilkenny “The book is well organized to teach cell culture and tissue engineering experiments to novice and experienced students. There is a quantitative emphasis in the book that strengthens the ‘engineering’ part of tissue engineering.”

—Ann Saterbak, Rice University, Houston, Texas, USA

“This book has a protocol-like style and can actually be used directly by teachers to prepare lab courses as well as by people with lab experience that enter the field of tissue engineering. … provides students with good insight in methods, techniques and approaches in the field of tissue engineering."

—Gerjo J.V.M. van Osch, Erasmus MC, University Medical Center Rotterdam, The Netherlands

“… a much-needed book for undergraduate bioengineering curricula. Tissue engineering is a topic best learned through practice, and this book just might take the fear out of offering a laboratory course on the subject."

—Michael J. Moore, Ph.D., Tulane University, New Orleans, USA

“… provides comprehensive coverage of laboratory techniques in tissue engineering, including detailed experimental protocols."

—Adam Higgins, Oregon State University, Corvallis, USA

A hands-on lab manual for tissue engineering instruction, this book contains 15 standalone experiments based on both classic and modern approaches. Experiments encompass a set of widely applicable techniques: cell culture, microscopy, histology, immunohistochemistry, mechanical testing, soft lithography, and common biochemical assays.

Albert Folch University of Washington, Seattle, USA

“The field has been waiting for a true textbook that provides a practical, historical, authoritative and comprehensive introduction to bioMEMS. It has finally arrived, courtesy of Albert Folch, complete with PowerPoint lectures and thoughtful homework questions.”

—David J. Beebe, University of Wisconsin–Madison

“... successfully integrates microfabrication and the physics of microfluidics with numerous biological applications. It provides a visual feast of images that lead to a comprehensive understanding of many complex concepts. Applications presented range from biomolecules to cells, tissues, and organisms, and are presented in clear, logical steps. It serves as an outstanding text for advanced undergraduates and graduate students ...”

—Dr. Fawwaz Habbal, Harvard University

“With extensive citations of the current literature, explanations that really put the technology in context, clear enunciation of the motivations for miniaturization, and historical perspective, the author has made the material very accessible and clear … . I definitely recommend this textbook for bioengineering students.”

—Professor Karen C. Cheung, University of British Columbia

“... a monumental achievement which brings an authoritative and comprehensive account to the rapidly growing, multidisciplinary field of bioMEMS.” —Mehmet Toner, Helen Andrus Benedict Professor of Bioengineering, Harvard Medical School, USA

This classroom-tested book—in color throughout— covers the whole breadth of this dynamic field, including classical microfabrication, microfluidics, tissue engineering, cell-based and noncell-based devices, and implantable systems.

Pedagogical Features

Pedagogical Features

• Fifteen standalone experiments, allowing you to customize your courses • Prelab and postlab questions for each experiment • More than 70 illustrations

• Fundamental concepts highlighted and defined in an extensive glossary • More than 400 color figures, problem sets, design challenges, and key references • Downloadable PowerPoint® slides for instructors

A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. K13694, August 2012, 304 pp.

Soft Cover, ISBN: 978-1-4398-7893-4 $59.95 / £38.99 Also available as an eBook

An instructor's manual is available upon qualifying course adoption.

Catalog no. K10966, August 2012, 528 pp.

ISBN: 978-1-4398-1839-8, $89.95 / £57.99 Also available as an eBook

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Bio MEMS, NEMS & Materials From MEMS to Bio-MEMS and Bio-NEMS Manufacturing Techniques and Applications Marc J. Madou University of California, Irvine, USA

This textbook details manufacturing techniques applicable to bio-nanotechnology. After reviewing MEMS techniques, materials, and modeling, the author covers nanofabrication, genetically engineered proteins, artificial cells, nanochemistry, and self-assembly.

BioMEMS Science and Engineering Perspectives Simona Badilescu and Muthukumaran Packirisamy Concordia University, Montreal, Quebec, Canada

Features

BioMEMS: Science and Engineering Perspectives supports and expedites the multidisciplinary learning involved in the development of biomicrosystems. Divided into nine chapters, it starts with a balanced introduction of biological, engineering, application, and commercialization aspects of the field.

• Focuses on applications of NEMS and MEMS

The book also discusses:

• Covers scaling laws, actuators, and fluidics

• Different materials and platforms used to develop biomicrosystems

• Discusses top-down and bottom-up manufacturing methods • Explains how to use nature as a guide

• Various biological entities and pathogens (in ascending order of complexity)

Pedagogical Features

• The multidisciplinary aspects of engineering bioactive surfaces

• End-of-chapter problems • Color illustrations throughout

• Engineering perspectives, including methods of manufacturing bioactive surfaces and devices

• Extensive references for further reading

• Microfluidics modeling and experimentation

• A comprehensive glossary of terms

• Device level implementation of BioMEMS concepts for different applications

• Worked-out problems within the text

A solutions manual, PowerPoint® lecture slides, and electronic figures are available upon qualifying course adoption.

Pedagogical Features

Selected Contents

• Examples and problems

From Traditional Manufacturing To Nanotechnology: Nonlithography-Based (Traditional) and Lithography-Based (Nontraditional) Manufacturing Compared.

Nature as an Engineering Guide: Biomimetics.

Nanotechnology: Top-Down and Bottom-Up Manufacturing Approaches Compared.

Packaging, Assembly, and Self-Assembly. Selected Materials and Processes for MEMS and NEMS. Metrology and MEMS/NEMS Modeling.

Scaling Laws, Actuators, and Power and Brains In Miniature Devices: Scaling Laws. Actuators.

Power and Brains in Miniature Devices.

Miniaturization Application: MEMS and NEMS Applications.

• Review questions

Catalog no. 5516X, June 2011, 650 pp.

ISBN: 978-1-4200-5516-0, $104.95 / £66.99 Also available as an eBook

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• Case studies A solutions manual is available upon qualifying course adoption.

Selected Contents Introduction. Substrate Materials Used in BioMEMS Devices. Biomolecules and Complex Biological Entities: Structure and Properties.

Engineering of Bioactive Surfaces. Methods of Study and Characterization of Surface-Modified Substrates. Biosensing Fundamentals. Fabrication of BioMEMS Devices. Introduction to Microfluidics. BioMEMS: Life Science Applications.

Catalog no. K10877, April 2011, 368 pp.

ISBN: 978-1-4398-1699-8, $104.95 / £66.99 Also available as an eBook

Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

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Bio MEMS, NEMS & Materials

Biomedical Microsystems Ellis Meng University of Southern California, Los Angeles, USA

Written by an active researcher named one of Technology Review’s Young Innovators Under 35, this book begins with an introduction to the benefits of miniaturization. It introduces materials, fabrication technology, and the necessary components of all BioMEMS. The author covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of BioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering.

Detailed examples, exercises, and illustrations help clarify the concepts.

A solutions manual is available upon qualifying course adoption.

Catalog no. 51229, September 2010, 408 pp.

ISBN: 978-1-4200-5122-3, $99.95 / £62.99 Also available as an eBook

Understanding Nanomedicine An Introductory Textbook Rob Burgess Medical Nanotechnologies Incorporated, Richardson, Texas, USA

"Dr. Burgess has done an excellent job in providing the much-needed background in the numerous physical, chemical, and biological methods that are used to enable nanomedicine. This book will be a useful reference for any student in the field of nanomedicine and describes many examples where nanotechnology promises to improve the diagnosis, monitoring, and treatment of disease” —Dr. Gareth Hughes, Medical Nanotechnologies, Inc., USA

This book comprehensively covers a broad range of therapeutic and diagnostic applications of nanotechnology, providing descriptions of cuttingedge discoveries along with historical perspectives.

Catalog no. N10477, June 2012, 524 pp.

ISBN: 978-981-4316-38-5, $149.95 / £95.00 Also available as an eBook

Bestseller

Biomaterials A Nano Approach Seeram Ramakrishna, Murugan Ramalingam, T.S. Sampath Kumar, and Winston O. Soboyejo From a multidisciplinary point of view, this book examines basic concepts, processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications. It spans their historical development and reviews recent advances in the field. It describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. Presenting illustrative examples and applications, this text offers a solid framework for understanding present and future trends of biomaterials in human health care systems.

Figure slides are available upon qualifying course adoption.

Catalog no. 47817, June 2010, 372 pp.

ISBN: 978-1-4200-4781-3, $104.95 / £73.99

Design of Biomedical Devices and Systems Second Edition Paul H. King and Richard C. Fries The second edition of a bestseller, this book provides a comprehensive overview of biomedical device and system design—including topics related to databases, process analysis, and device improvement—from a strong design perspective. It covers all aspects of design that must be considered for complex biomedical projects. This second edition features information on device definition and reliability, as well as testing and hardware verification, and each chapter has been updated to reflect advances in the field.

A solutions manual is available upon qualifying course adoption.

Catalog no. 61798, August 2008, 424 pp.

ISBN: 978-1-4200-6179-6, $129.95 / £82.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

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Biomedical Imaging Webb's Physics of Medical Imaging

Biomedical Signal and Image Processing

Second Edition Edited by

M.A. Flower

Second Edition

Institute of Cancer Research/Royal Marsden NHS Foundation Trust, UK

Kayvan Najarian and Robert Splinter

Series in Medical Physics and Biomedical Engineering

“Possibly the most comprehensive book on the subject currently on the market.”

—Dr. Sandro Olivo, University College London

Praise for the First Edition “Steve Webb has produced a first-class book.

Because The Physics of Medical Imaging is up to date in a rapidly changing field, it is the text of choice for teaching graduate research students in this new and exciting subspeciality of physics.”

—Physics Today

“… a worthwhile addition to the personal library of anyone connected with this field.”

—Journal of Clinical Physics and Physiological Measurement

“For all those requiring a comprehensive review of medical imaging techniques, at a fairly basic level, this text is highly recommended.”

—Australian Physicist

“This is a book well worth the money and I can strongly recommend it both as desk and bedside reading.”

—HPA Bulletin

“Developments in digital radiography, together with an analysis of the computing requirements of the various techniques, complete this excellent text. The authors have done a remarkable job in covering such a wide subject so well in such a short book.”

“... a great collection of topics ... highly recommended ..."

—Purang Abolmaesumi, University of British Columbia, Vancouver, Canada

“... balances the coverage of physics of biomedical imaging with biomedical image processing. … I was impressed by how clearly the concepts are explained."

—Shahram Shirani, McMaster University, Hamilton, Ontario, Canada

“… an excellent bridge between the physiological significance of the methods, and the underlying mathematics. … covers a broad range of biomedical problems. … clear, well written, and easy to follow. … this is an excellent course textbook, and also an excellent reference book for professionals."

—Dr. Kristian Sandberg, Computational Solutions, Inc., Boulder, Colorado, USA

Pedagogical Features • Numerous examples, many of which are MATLAB® based • End-of-chapter problems • Downloadable figures for presentations A solutions manual is available upon qualifying course adoption.

Selected Contents

In the Beginning: The Origins of Medical Imaging. Diagnostic Radiology with X-Rays. X-Ray Transmission Computed Tomography. Clinical Applications of X-Ray Computed Tomography in Radiotherapy Planning. Radioisotope Imaging.

Diagnostic Ultrasound. Spatially Localised Magnetic Resonance. Physical Aspects of Infrared Imaging. Imaging of Tissue Electrical Impedance.

Optical Imaging. Mathematics of Image Formation and Image Processing. Medical Image Processing. Perception and Interpretation of Images. Computer Requirements of Imaging Systems. Multimodality Imaging. Epilogue. Index.

Introduction To Digital Signal And Image Processing: Signals and Biomedical Signal Processing. Fourier Transform. Image Filtering, Enhancement, and Restoration. Edge Detection and Segmentation of Images. Wavelet Transform.

Other Signal and Image Processing Methods.

Clustering and Classification. Processing Of Biomedical Signals: Electrical Activities of Cell.

Electrocardiogram. Electroencephalogram.

Electromyogram. Other Biomedical Signals.

Processing Of Biomedical Images: Principles of Computed Tomography. X-Ray Imaging and Computed Tomography. Magnetic Resonance Imaging. Ultrasound Imaging. Positron Emission Tomography. Other Biomedical Imaging Techniques. Related Titles.

Catalog no. IP743, June 2012, 864 pp.

ISBN: 978-0-7503-0573-0, $89.95 / £49.99 Also available as an eBook

Catalog no. K13235, May 2012, 411 pp.

ISBN: 978-1-4398-7033-4, $99.95 / £63.99 Also available as an eBook

—Image Processing Magazine

Selected Contents

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Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

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Biomedical Imaging

Applied Medical Image Processing A Basic Course Wolfgang Birkfellner Medical University of Vienna, Austria

“The topics covered are clearly explained, including explanations of the mathematical operations that are required, therefore making it an ideal text for anyone who is new to medical image processing.”

—Sarah Cade, Scope, December 2011

“The CD adds substantial value … Several books on image processing have been published recently, and this book takes a backseat to none of them. …

Students who take a course where this book is used as the course text will be fortunate indeed.”

—William Hendee, Medical Physics, Vol. 37, December 2010

“... an outstanding work that will be of interest to virtually all biomedical engineers. ... important concepts and definitions are described concisely and well. ... a well-written, coherent, and comprehensive work covering the major topics in the field ...”

—Edward J. Ciaccio, Columbia University, BioMedical Engineering OnLine, 2011

“... a lucid, well-written, and hands-on textbook that explains in simple terms and with examples the basic issues of medical image processing.”

—Prof. Leo Joskowicz, The Hebrew University of Jerusalem

“The plethora of examples in each chapter … allows the reader to apply the theory and visually assess the outcomes. ... a perfect blend of theory and practice. I highly recommend it.”

—Dr. Pascal Fallavollita, Technische Universität München

Pedagogical Features • Numerous diagrams and figures • Many practical examples for MATLAB® and Octave with a CD featuring image material and program files Selected Contents A Few Basics of Medical Image Sources. Image Representation. Operations in Intensity Space.

Segmentation. Filtering and Transformations.

Spatial Transforms. Rendering, Visualization, and Surface Models. Registration. Volume Reconstruction. Appendix. Glossary. Index.

Catalog no. K11176, September 2010, 403 pp.

ISBN: 978-1-4398-2444-3, $76.95 / £48.99 Also available as an eBook

Forthcoming

Practical Ultrasound An Illustrated Guide, Second Edition Jane Alty, Edward Hoey, Michael Weston, and Stephen Wolstenhulme Practical Ultrasound contains everything you need to know to become competent in learning the skills of ultrasound scanning. This essential illustrated guide will enable you to use the equipment and interpret the images on screen accurately. It uses illustrations, accurate images, and uncomplicated language throughout to ensure that this guide is practical and easy to use. In addition, it includes step-by-step sections on how to perform ultrasound scans, which are supplemented by high-quality images and handy hints.

Catalog no. K17225, March 2013, c. 282 pp.

Soft Cover, ISBN: 978-1-4441-6829-7 $79.95 / £49.99

Forthcoming

Introduction to Nuclear Science Second Edition Jeff C. Bryan University of Wisconsin, La Crosse, USA

This introductory text covers general aspects of nuclear chemistry and physics. It discusses how nuclear science impacts our daily lives through medicine, electrical power generation, food safety, waste, and weapons. This edition features new chapters that address nuclear reactors, dosimetry, radiochemistry, and nuclear forensics. It also expands coverage of nuclear medicine and radiation therapy. With additional end-of-chapter problems, the text supplies critical information for students earning nuclear-related degrees, as well as providing an accessible reference for anyone with an interest in nuclear issues.

A solutions manual is available upon qualifying course adoption.

Catalog no. K14329, March 2013, c. 416 pp.

ISBN: 978-1-4398-9892-5, $89.95 / £57.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

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Biophysics Ultrasonic and Electromagnetic NDE for Structure and Material Characterization Engineering and Biomedical Applications Edited by

Tribikram Kundu

The University of Arizona, Tucson, USA

“... an essential reference for researchers and graduate students working in ultrasonic or electromagnetic NDE. The different chapters contributed by recognized experts in the field cover both fundamental theory as well as current research areas.”

—Dr. Paul Fromme, University College London, UK

“... provides a comprehensive and rigorous approach of the fundamentals of linear and nonlinear ultrasonics and electromagnetic methods ... also provides enough advanced engineering and biological applications to make the reader familiar with these technologies ... an excellent text for a senior/first-year graduate course in nondestructive testing and evaluation, or as a text in a course in engineering and biological materials characterization. It is also an excellent reference book for practicing engineers and scientists, and I highly recommend it.”

—Henrique Reis, University of Illinois at Urbana-Champaign, USA

Pedagogical Features • Questions, problems, and worked-out examples • More than 640 illustrations A solutions manual is available upon qualifying course adoption.

Selected Contents Mechanics of Elastic Waves and Ultrasonic Nondestructive Evaluation. Modeling of Ultrasonic Fields by Distributed Point Source Method.

Electromagnetic Nondestructive Evaluation.

Distributed Point Source Method for Imaging in Electrostatic and Electromagnetic Problems. Guided Waves for Plate and Pipe Inspection. Fundamentals and Applications of Nonlinear Ultrasonic Nondestructive Evaluation. Theory and Applications of Laser Ultrasonic Techniques. Material Characterization by Nonlinear Ultrasonic Technique.

Toward Structural Health Monitoring Solutions for Bolted Joints. Measurement of the Elastic Properties of Solids by Brillouin Spectroscopy. ...

Catalog no. K11655, June 2012, 890 pp.

ISBN: 978-1-4398-3663-7, $149.95 / £95.00 Also available as an eBook

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Quantitative Understanding of Biosystems An Introduction to Biophysics Thomas M. Nordlund University of Alabama at Birmingham, USA

“… highly recommended for introducing biophysics to the motivated and curious undergraduate students.”

—Nikolaos Kourkoumelis, Contemporary Physics, June 2012

“This terrific text offers a broad range of learning opportunities for many undergraduate majors. … It will enable students to understand the significance of biological parameters through quantitative examples—a modern way of learning biophysics.”

—American Journal of Physics, February 2012

“... a beautiful review of essential physics for understanding biological systems ... emphasizing that which is rarely taught in standard physics classes: how to think like a physicist.”

—Ernest Barreto, George Mason University A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. 89772, March 2011, 583 pp.

ISBN: 978-1-4200-8972-1, $93.95 / £59.99 Also available as an eBook

New

Physical Chemistry for Engineering and Applied Sciences Frank R. Foulkes This book is the result of more than 30 years of teaching by the author of a onesemester course in physical chemistry to first-year students at the University of Toronto. The enrollment varied from 300 to 800 students per year over the years.

The book is unique in that it provides the detailed development of the equations, which can be followed relatively easily even with only moderate mathematical skills and backgrounds. The book provides interesting and inspiring examples, as well as many problems and solutions.

A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. K15157, September 2012, 703 pp.

ISBN: 978-1-4665-1846-9, $89.95 / £57.99 Also available as an eBook

Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

AJM01 5.5x8.5 TMC_AJM01_TMC 1/3/13 2:08 PM Page 17

Biophysics New

Molecular Motors in Bionanotechnology Keith Firman and James Youell University of Portsmouth, UK

Many techniques have evolved to study and characterize molecular motors at the single-molecule level, such as the use of molecular tweezer devices for single-molecule studies. This book describes a wide range of molecular motors, from chemical to biological. It introduces readers to the concepts and benefits of each technique and looks at structural information and how this helps to understand function. The book also examines how some of these motors are being used or may be used in the future as part of a synthetic biology approach to building devices and sensors.

Catalog no. N10568, November 2012, 300 pp.

ISBN: 978-981-4267-02-1, $149.95 / £95.00 Also available as an eBook

Dynamics of Biological Systems Michael Small Hong Kong Polytechnic University Series: Chapman & Hall/CRC Mathematical & Computational Biology

With exercises and projects in each chapter, this classroom-tested text shows how to apply a variety of mathematical and computational techniques to model and analyze the temporal and spatial phenomena of biological systems. The mathematical models and computer simulations offer insight into cardiac pacemakers, artificial electrical defibrillation, pandemics, pattern formation, flocking behavior, the interaction of autonomous agents, and hierarchical and structured network topologies. MATLAB® implementations of algorithms and case studies are available on the author’s website.

A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. K12463, August 2011, 284 pp.

ISBN: 978-1-4398-5336-8, $79.95 / £49.99 Also available as an eBook

Physics for Diagnostic Radiology Third Edition Philip Palin Dendy Addenbrookes NHS Trust, Cambridge, UK

Brian Heaton Aberdeen Radiation Protection Services, UK

“This is the third edition of a well-established and popular textbook on physics of diagnostic radiology. It is a textbook written in a clear and concise style, supported by excellent illustrations. The textbook describes recent state-of-the-art advances in medical imaging in a way radiologists, radiographers and medical physicists will find easy to understand. It is internationally recognised as one of the key textbooks in its field.”

—Dr. Keith Faulkner, North East Strategic Health Authority, UK

Fully revised and updated, this bestselling text helps readers understand how various imaging techniques work.

Catalog no. 83155, August 2011, 720 pp.

ISBN: 978-1-4200-8315-6, $79.95 / £49.99 Also available as an eBook

Physiology, Biophysics, and Biomedical Engineering Edited by

Andrew W. Wood Swinburne University of Technology, Hawthorn, Victoria, Australia

Showing how biophysics and biomedical engineering have advanced modern medicine, this text provides a multidisciplinary understanding of biological phenomena and the instrumentation for monitoring these phenomena. It also explores the application of physics and engineering methods to medicine and biology. The book includes a range of numerical problems with worked solutions and offers MATLAB® code for advanced mathematical analysis of physiological and clinical monitoring systems.

A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. C6513, February 2012, 782 pp.

ISBN: 978-1-4200-6513-8, $99.95 / £49.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

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Biotechnology New

Learning Bio-Micro-Nanotechnology Mel I. Mendelson Loyola Marymount University, Los Angeles, California, USA

"… a great combination of two key disciplines in the coming quarter of this century, biotechnology and nanotechnology. This will be a good guidebook for the academic adventure as well as a bible for the pioneer in the engineering and scientific field."

—Hideyuki Kanematsu, Suzuka National College of Technology

"… provides an excellent, multi-dimensional approach to learning that I have not seen in other nanotechnology text books. … I really like the multitude of ways the author has the students think about the material through problems, group activities, thinking exercises, etc."

—Kory Goldammer, Richland College

Learning Bio-Micro-Nanotechnology is a primer on micro/nanotechnology that teaches the vocabulary, fundamental concepts, and applications of micro/nanotechnology in biology, chemistry, physics, engineering, electronics, computers, biomedicine, microscopy, ethics, and risks to humankind. It provides an introduction into the small world with a low fog index, emphasizing the concepts using analogies and illustrations to simplify the non-observables.

Features • Introduces the micro/nanotechnology vocabulary, concepts, and applications from first principles • Breaks down the barriers between biology, chemistry, physics, engineering, and ethics with cross-disciplinary coverage • Includes biology, chemistry, physics, engineering, microscopy, electronics and computers, and micro-technology • Discusses nanotechnology and cancer, risks, ethics, and future predictions Pedagogical Features • Case studies, thinking exercises, and analogies • Study questions using Bloom’s taxonomy, team assignments, and assessment exercises • A math review and glossary of terms in the appendix A solutions manual is available upon qualifying course adoption.

Selected Contents Thinking Small and Big Introduction. Bit of Technology History. Tera-toPico Multipliers. Size of Things. What Is "Small Technology?". ...

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Biomolecules and Cells Introduction. Science of Evolution. Powers of "10" Revisited. Building a Human Cell. Biomolecules.

Protein Folding. Identifying Biomolecules. ...

Molecular Chemistry Introduction. Periodic Table. Some Chemical Definitions. Chemical Bonding. Macromolecules.

Polymer Examples. Colloids. Solid Nanomolecules.

Bit of Physics Introduction. Size Matters. Working toward the Bottom. Definitions at the Bottom. ...

Engineering Bits and Bytes Introduction. Electronics-on-a-Chip. Computer Applications. Control Systems.

Seeing Small Things Introduction. Human Eye. Some Microscope Definitions. Light Microscopes. Electron Microscopes.

Nanoelectronics Introduction. Computer Applications.

Lithographic Tools. Recent Chip Developments.

Emerging Technology. Bottom-Up Technology.

Microelectromechanical Systems Introduction. Overview. Microsensors.

Microactuators. Biochips.

Nanotechnology and Cancer Introduction. What Is Cancer? Discovery: L. Detection: I. Delivery: T. Destruction: R. Risks: Nano or Mega?

Introduction. Bit of Anatomy. Definitions Relating to Risk. Chemical and Physical Factors. Benefits versus Risks. Risk Assessment. Risk Management.

Ethics and Social Relevance Introduction. Some Ethics Definitions. ...

Self-Assembled Future Introduction. Definition: Self-Assembled Future.

Geometric Proportions. Chemical Assembly. Snow Flake Assembly. Self-Assembled Colloids. ...

Appendices Math Review: Multiplying and Dividing Exponents. Math Review: Dimensional Analysis.

Math Review: No. of Ways and Probability. ...

Chapters include key concepts, questions and problems, and references.

Catalog no. 82035, January 2013, 611 pp.

ISBN: 978-1-4200-8203-6, $89.95 / £57.99 Also available as an eBook

Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

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Biotechnology

New

Introduction to Instrumentation in Life Sciences Prakash Singh Bisen Defense Research & Development Establishment, Gwalior, India

Anjana Sharma Rani Durgavati University, Jabalpur, India

Instrumentation is central to the study of physiology and genetics in living organisms, especially at the molecular level. Numerous techniques have been developed to address this in various biological disciplines, creating a need to understand the physical principles involved in the operation of research instruments and the parameters required in using them. Introduction to Instrumentation in Life Sciences fills this need by addressing different aspects of tools that hold the keys to cutting-edge research and innovative applications, from basic techniques to advanced instrumentation. The text describes all topics so even beginners can easily understand the theoretical and practical aspects.

"A comprehensive text book on instrumentation methods which covers all major topics including practical exercises representing the syllabi of various postgraduate and undergraduate programmes in life sciences."

Comprehensive chapters encompass well-defined methodology that describes the instruments and their corresponding applications in different scientific fields. The book covers optical and electron microscopy; micrometry, especially in microbial taxonomy; pH meters and oxygen electrodes; chromatography for separation and purification of products from complex mixtures; spectroscopic and spectrophotometric techniques to determine structure and function of biomolecules; preparative and analytical centrifugation; electrophoretic techniques; and much more.

Features

The book is designed to serve a wide range of students and researchers in diversified fields of life sciences: pharmacy, biotechnology, microbiology, biochemistry, and environmental sciences. It introduces different aspects of basic experimental methods and instrumentation. The book is unique in its broad subject coverage, incorporating fundamental techniques as well as applications of modern molecular and proteomic tools that are the basis for stateof-the-art research.

"The proposed book is an excellent one for use of students, research scholars and teachers of life sciences, biotechnology, biochemistry, biophysics and other related disciplines where such books exclusively dedicated for life sciences are not available."

—Prof. Sukh Mahendra Singh, Coordinator, School of Biotechnology, Banaras Hindu University, India

—Prof. Vinay Sharma, Professor and Head, Department of Bioscience and Biotechnology, Banasthali University, India

"I find that the book should be much useful for undergraduate (bachelor’s degree) and graduate (master’s degree) students. Very good book, properly arranged topics, will certainly be useful for the audience."

—Anil Kumar, Ph.D., Professor and Head (Chair), School of Biotechnology, Devi Ahilya University, India

• Provides a comprehensive, detailed overview of techniques and usage of key instrumentation needed in biotechnology and life sciences • Includes basic theoretical and practical details for numerous types of chromatography, such as column, thin-layer, and high-performance liquid chromatography • Describes a broad range of spectroscopic techniques, including UV/visible, fluorescence, NMR, and circular dichroism spectroscopy • Covers electrophoretic techniques and their applications for deciphering the molecular nature of cell components as well as in gene technology • Contains unique in-depth coverage of fermentation processes • Offers an excellent bench manual for researchers Figure slides are available upon qualifying course adoption.

Selected Contents Microscopy. Micrometry. Electrochemical Techniques. Chromatography. Spectroscopy.

Centrifugation. Electrophoresis. X-Ray Microanalysis. Techniques with Radioisotopes.

Fermentation. Conductivity Meters. Glossary.

Index.

Catalog no. K14893, September 2012, 383 pp.

Soft Cover, ISBN: 978-1-4665-1240-5 $79.95 / £49.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

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Biotechnology Biotechnology Fundamentals Firdos Alam Khan Manipal University, Dubai, UAE

This textbook discusses the fundamentals of biotechnology as well as the latest developments such as stem cell research, cloning, biofuel, transgenic plants, genetically modified food or crops, pharmacogenomics, and nano-biotechnology. Incorporating extensive pedagogy into the content, the authors provide examples, end-of-chapter problems, case studies, and laboratory tutorials.

Features • Includes information on current research trends • Covers novel medical genetics topics such as intra-uterine insemination • Discusses the process of biotech product development, with suitable examples • Examines ethical issues within biotechnology research and product development (e.g. embryonic stem cells, cloning, gene therapy, and GM crops) Pedagogical Features • • • •

Learning objectives for each chapter End-of-chapter problems Lab assignments Suggestions for field trips A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction to Biotechnology Genes and Genomics Proteins and Proteomics Recombinant DNA Technology Microbial Biotechnology Agricultural Biotechnology Animal Biotechnology Environmental Biotechnology Medical Biotechnology Nanobiotechnology Product Development in Biotechnology Industrial Biotechnology Ethics in Biotechnology Careers in Biotechnology Laboratory Tutorials Glossary Catalog no. K11059, September 2011, 608 pp.,ISBN: 978-1-4398-2009-4, $93.95 / £49.99 Also available as an eBook

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Biotechnology Operations Principles and Practices Michael J. Roy University of Wisconsin-Madison, USA

Applying the author's experience teaching the subject and working in both industry and government, Biotechnology Operations: Principles and Practices introduces key biotechnology developments and covers critical elements, such as project management, regulatory affairs, quality assurance, biomanufacturing, quality control, nonclinical safety testing, and clinical evaluation.

Features • Provides an introduction to each key biotechnology development subject, all compiled in one volume • Incorporates an integrated approach, tying together the seven key functional areas • Emphasizes the need to both plan and integrate an operations program, offering the information required to successfully lead such efforts • Uses relatively simple language, clarifies jargon, and uses diagrams to describe processes, making concepts easy to understand Pedagogical Features • Practical problems and questions • A glossary A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction to Biotechnology Operations: Planning for Success Project Management Regulatory Affairs Regulatory Compliance Quality Systems Biomanufacture Quality Control Nonclinical Studies Clinical Trials Glossary Additional Reading Practical Problems and Questions Catalog no. K11486, March 2011, 416 pp.

ISBN: 978-1-4398-3027-7, $104.95 / £66.99 Also available as an eBook

Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

AJM01 5.5x8.5 TMC_AJM01_TMC 1/3/13 2:08 PM Page 21

Biotechnology Healthcare Biotechnology A Practical Guide Dimitris Dogramatzis Dogramatzis Pharmacy, Athens, Greece

"The section on marketing is also particularly strong and well thought through. ... provides insight into the biotechnology business sector."

—British Journal of Biomedical Science

Focusing on the management of healthcare related biotechnology, this is a practical guide assisting professionals in their day-to-day activities. It contains chapters on bioeconomy, biolicensing, biofinance, biopartnering, biodrug research, biomarket planning, biopromotion, product life-cycle management, and biobusiness models. Written by a wellestablished professional and registered pharmacist, this reference is appropriate for graduate students and industry professionals.

A solutions manual, instructor’s manual, and figure slides are available upon qualifying course adoption.

Catalog no. K12108, December 2010, 689 pp.

ISBN: 978-1-4398-4746-6, $109.95 / £69.99 Also available as an eBook

Environmental Microbiology for Engineers Volodymyr Ivanov Nanyang Technological University, Singapore

Designed specifically for engineers with little or no biology training, this book covers diversity and function of microorganisms in environmental engineering systems, environmental bioengineering processes, applied microbial genetics and molecular biology, microbiology of water and wastewater treatment, biotreatment and bioremediation, and microbial monitoring. It also explores biocorrosion of the constructions, biodeterioration of the materials, biocementation and bioclogging of soil, biopollution of indoor environment, and biofouling of the facilities.

Each chapter includes quizzes and tutorials.

A solutions manual is available upon qualifying course adoption.

Catalog no. 92340, November 2010, 438 pp.

ISBN: 978-1-4200-9234-9, $109.95 / £69.99 Also available as an eBook

Systems Biology and Bioinformatics A Computational Approach Kayvan Najarian, Christopher N. Eichelberger, Siamak Najarian, and Shahriar Gharibzadeh Emphasizing computational methods, Systems Biology and Bioinformatics provides an introduction to systems biology and its impact on biology and medicine. It reviews basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the highthroughput biological experiments that produce databases. The methods presented include techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. It also explains applications for system-oriented models to predict the behavior of biological systems.

A solutions manual is available upon qualifying course adoption.

Catalog no. 46500, April 2009, 190 pp.

ISBN: 978-1-4200-4650-2, $79.95 / £49.99 Also available as an eBook

Colloids and Interfaces in Life Sciences and Bionanotechnology Second Edition Willem Norde This classroom-tested reference presents a concise introductory treatment of the physicochemical principles that determine interrelated colloidal and interfacial phenomena and their relevance to various life sciences. The book focuses on concepts that form the basis for understanding this behavior. It deciphers the spontaneous assembly of amphiphilic molecules and discusses the intentional fouling of surfaces for the immobilization of cells in bioreactors. It also devotes special attention to reversible and soft colloids and examines the colloidal domain in a historical perspective, the size and distribution of particles, electrokinetic phenomena, and more.

Catalog no. K10890, June 2011, 495 pp.

ISBN: 978-1-4398-1718-6, $134.95 / £39.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

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General Textbooks Forthcoming

Numerical Methods for Chemical Engineers Using Excel, VBA, and MATLAB® Victor J. Law Since most practical engineering problems must be solved numerically, this text provides instruction on using numerical methods and Excel®/VBA for chemical and biomolecular engineering problems. It also includes an introduction to MATLAB®. The book is the first to apply numerical methods specifically for chemical engineers in the Excel/VBA computing environment. All examples and exercises emphasize chemical and biomolecular engineering applications. The book also contains homework problems in each chapter.

A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. K16702, March 2013, c. 252 pp.

ISBN: $59.95 / £38.99 Also available as an eBook

A First Course in Differential Equations, Modeling, and Simulation Carlos A. Smith and Scott W. Campbell Emphasizing a practical approach for engineers and scientists, this text avoids overly theoretical explanations and shows readers how differential equations are derived by applying basic physical principles and experimental observations to engineering systems. This resource also covers classical methods for obtaining the analytical solution of differential equations and Laplace transforms. In addition, the authors discuss how these equations describe mathematical systems and how to use software to solve sets of equations in which analytical solutions cannot be determined. Numerical values are provided in all examples and problems.

A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. K12318, May 2011, 345 pp.

ISBN: 978-1-4398-5087-9, $93.95 / £59.99 Also available as an eBook

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Technical Writing A Practical Guide for Engineers and Scientists Phillip A. Laplante Written by a renowned engineer and widely published technical author, this guide enables readers to write, edit, and publish materials of a technical nature, including books, articles, reports, and electronic media. Complementing the traditional writer’s reference manuals and other books on technical writing, it helps readers understand the practical considerations in writing technical content. Drawing on his own work, the author presents many first-hand examples of writing, editing, and publishing technical materials. These examples illustrate how a publication originated as well as various challenges and solutions.

Catalog no. K11106, July 2011, 250 pp.

Soft Cover, ISBN: 978-1-4398-2085-8 $41.95 / £26.99 Also available as an eBook

Random Phenomena Fundamentals of Probability and Statistics for Engineers Babatunde A. Ogunnaike “... distinguished from the crowded field by the well-explained theory of statistics and how it provides interesting applications.”

—Walid K. Sharabati, The American Statistician, August 2011

“... many unique features ... Instructors who are looking for an alternative textbook should give a serious consideration to adopting this book.”

—Ali Cinar, Technometrics, August 2011

“I would have loved to be taught from a book like this and I heartily recommend this book as a classroom textbook for both the clarity of the explanations and the amount of material covered.”

—Pieter Bastiaan Ober, Journal of Applied Statistics, 2011 A solutions manual is available upon qualifying course adoption.

Catalog no. 44974, September 2009, 1056 pp.

ISBN: 978-1-4200-4497-3, $146.95 / £94.00 Also available as an eBook

Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

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