The Community Health Needs Assessment (CHNA) is a systematic, data-driven approach to determine the health needs in the service area of the University of Chicago Medical Center (UCMC). This report provides the process involved in conducting the CHNA, summarizes data for community health needs, and provides a profile for the communities within the UCMC service area (UCMCSA). A subsequent strategic implementation plan will detail the strategies that will be employed to address the health needs in the community.