IBD Phenotypes and Outcomes In Black and Hispanic Patients: A Multicenter Longitudinal Study
Prepared for The Color of Crohn’s and Chronic Illness, Inc.
August 2023
PHILANTHROPIC IMPACT REPORT
Damie Odufalu, MD, Research Study
Thank you for being a thought leader at the forefront of equity and IBD care and a resource for patients with IBD to learn more about the disease and find a community they feel safe with. Your support of Dr. Damie Odufalu will ultimately improve the care given to hundreds of thousands of people across the nation. On behalf of Dr. Odufalu, the Division of GI and Liver Disease at Keck Medicine of USC, and all those who will benefit from their work, we thank you for your vision, investment, and partnership.
Preliminary Data
Have a high school education or more
Dr. Odufalu’s Mission
To research IBD in Black and Hispanic patients, and by understanding the social determinants of health, gain insight into where we are not meeting patients of color.
Los Angeles General Medical Center
Black or Hispanic
Make less than $25,000 annually
IBD Phenotypes and Outcomes In Black and Hispanic Patients: A Multicenter Longitudinal Study: Philanthropic Impact Report Keck School of Medicine of USC 2
25% 80% 68% 57% 84% 55% Unusually high cohort for this disease
public transport to get to their medical appointments English as the preferred language
or state-sponsored health insurance
Use
MediCal
Strong trust in health care and their physicians
5% Reported little to no trust
Clinical Treatment History of Cohort
While the majority of patients in our first sample have received steroid treatments after a diagnosis of IBD, a significant percentage of patients have not been exposed to the most advanced treatments for IBD: biologics and immunomodulators.
Have 86% 35% 43%
Never
Outcomes
Never
We are in the preliminary stages of reviewing patient data and learning about patient outcomes. In the next year, we aim to have data to evaluate the following for Black and Hispanic patients:
Dr. Odufalu will use both colonoscopy results and patient response to measure outcomes of treatment. She also plans to examine remission rates and duration of hospital stay to indicate treatment effectiveness.
Next Steps
IBD Phenotypes and Outcomes In Black and Hispanic Patients: A Multicenter Longitudinal Study: Philanthropic Impact Report Keck School of Medicine of USC 3
used steroids
used biologics
Dr. Odufalu plans to expand the study to include another site and a more robust sample. The goal is to make this a longitudinal study, so she would like as many enrollees as possible to broaden the study’s impact. “As scientists, we want to generate results that apply beyond a specific region and expanding to a second medical center allows us to broaden our understanding of and treatment for IBD and Crohn’s.” used immunomodulators Pill: dosage and duration Infusion: dosage and duration Surgical intervention
New, Related Research
Dr. Odufalu recently completed another study on the differences in vaccination beliefs among patients with IBD. Her results show participants from underrepresented racial and ethnic minority groups were more likely to be hesitant to receive vaccinations compared to white participants, which may contribute to health care disparities in IBD patients. These findings will be presented at the ACG 2023 Annual Scientific Meeting in Vancouver, Canada in October 2023.
Thank you!
All of this is made possible through your support and investment, and we look forward to keeping you updated on what we discover as the research continues.
Damie Odufalu, MD Assistant Professor of Clinical Medicine
IBD Phenotypes and Outcomes In Black and Hispanic Patients: A Multicenter Longitudinal Study: Philanthropic Impact Report Keck School of Medicine of USC 4
