(EN) Brochure Brain Potential - Montreux

EDITION AUGUST 2026

MONTREUX

BR AIN POTENTIAL PRO GR A M

T H E W O R L D ’ S F I R S T L O N G E V I T Y P R O G R A M B U I LT O N A P U B L I S H E D S C I E N T I F I C M O D E L O F B R A I N H E A LT H

Brain Potential Program

Edition August 2026

THE WORD WAS THERE. AND THEN IT WASN’T. You are mid-sentence and the name goes. A colleague of fifteen years. A word you have used a thousand times. It returns three minutes later, and you carry on.

It happens to everyone. That is what you tell yourself, and it is true.

But something has changed in how you receive it. You used to laugh. Now you make a note of it. You remember that it happened last month as well. Somewhere along the way you began keeping a private count — one you have mentioned to no one.

You are not ill. You are not declining. You are simply no longer certain, and there is nowhere to take the uncertainty. Your doctor will tell you it is normal. Your family will tell you not to worry. Neither of them is measuring anything.

WHAT UNSETTLES YOU IS NOT THE FORGETTING. IT IS NOT KNOWING WHETHER IT MEANS ANYTHING.

Brain Potential Program

Edition August 2026

IF YOU RECOGNIZE YOURSELF, THIS PROGR AM WAS DESIGNED FOR YOU. Brain Potential is built for people whose

WH AT YO U A R E FEELI N G

thinking still carries their life — and who

― Names and words arrive more slowly than they used to.

have begun to sense that it no longer does so effortlessly. Executives and founders in their most cognitively demanding decade.

People who watched a parent or grandparent decline and have never quite stopped reading themselves against it. People who would rather have a measurement than a

― You reread the same paragraph to make it hold. ― Focus fragments earlier in the day than it once did. ― You rely on notes for what you used to simply carry.

reassurance.

― Cognitive work that was once effortless now leaves you tired.

It is equally relevant to those with no

― A diagnosis in your family has changed how you read your own lapses.

symptoms at all — who understand that the decades in which the brain is most responsive are the decades in which nothing appears to be wrong.

― You want to know where you actually stand — not to be told not to worry.

Brain Potential Program

Edition August 2026

MOST PEOPLE BELIEVE THIS IS SIMPLY WHAT AGEING DOES. THE EVIDENCE SAYS OTHERWISE. In a national survey of more than three thousand adults over forty, 58% said they believed cognitive decline is inevitable, and two-thirds expected to experience it themselves 1 . Almost half thought it likely they would develop dementia. Fewer than a third believed that how they live could meaningfully change that 2.

The published evidence points the other way. The 2024 Lancet Commission on dementia prevention concluded that around 45% of dementia cases worldwide are potentially preventable by addressing fourteen modifiable risk factors across the life course 3 — among them blood pressure, LDL cholesterol, physical inactivity, sleep, hearing, and social isolation. And the biology moves long before the symptoms do. The structural and molecular changes associated with cognitive decline begin to accumulate fifteen to twenty years before anything becomes apparent4 — which means the window in which the trajectory is most responsive is precisely the window most people spend waiting for a reason to act.

THE

ASSUMPTION

W H AT T H E E V I D E N C E S H O W S

>

A substantial share of risk is modifiable — and modifiable earlier than most people assume.

Nothing can be done until symptoms appear. >

Structural change is measurable long before symptoms, and most responsive at that stage.

Decline is inevitable.

Memory is the thing to watch.

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Memory is a late signal. Vascular, metabolic, inflammatory and sleep processes move first.

Brain health is a question for later life.

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The midlife decades are when the trajectory is most open to change.

A cognitive test tells you where you stand.

>

A cognitive test measures output. Imaging and biology measure the substrate producing it.

1 A ARP nationally representative sur vey of adult s aged 40+, N=3,022, 2021; repor ted in Mehegan L. & Rainville C., Innovation in Aging, 2023.

2 A ARP, Views About Brain Health and Dementia: Adult s 50 -Plus, March 2025 (30% significantly / 40% slightly).

3 Livingston G. et al., Dementia prevention, inter vention, and care: 2024 repor t of the Lancet standing Commission. The Lancet, 2024.

4 Established preclinical-phase literature; consistent with Mayo Clinic lifespan biomarker timeline published in Alzheimer’s & Dementia, 2026.

Brain Potential Program

A PU BL ISHED MODEL OF BR A IN HE A LT H. T WO Y E A R S IN T HE M A K ING .

Brain Potential did not begin as a program. It began as a research question.

Over two years, Clinique La Prairie’s Longevity Innovation department worked with the Laboratory for Research in Neuroimaging (LREN) at Lausanne University Hospital — CHUV — to establish what brain health actually is, how it can be measured, and which of its determinants can be changed. The collaboration was led on the CHUV side by Associate Professor Bogdan Draganski, Director of LREN and a member of Clinique La Prairie’s Independent Scientific Committee.

The work culminated in a peer-reviewed publication in Neuroscience & Biobehavioral Reviews — an open-access synthesis of the evidence linking lifetime exposures to brain trajectories in ageing. From it emerged the scientific model on which this program is built.

Its central proposition is this: brain health is not a single faculty to be tested. It is the outcome of five determinants — each measurable, and each modifiable.

R E A D T H E P U B L I C AT I O N García-García I., Donica O., Cohen A. A., Gonseth Nusslé S., Heini A., Nusslé S., Pichard C., Rietschel E., Tanackovic G., Folli S., Draganski B. Maintaining brain health across the lifespan. Neuroscience & Biobehavioral Reviews, 2023;153:105365. Open access. doi.org/10.1016/j.neubiorev.2023.105365

Edition August 2026

T H E F I V E M O D I F I A B L E D E T E R M I N A N T S O F B R A I N H E A LT H

I — NUTRITION W H AT R E A C H E S T H E B R A I N

Diet composition, micronutrient status and the gut–brain axis shape neuronal function and the inflammatory environment the brain operates in.

II — PHYSICAL ACTIVITY W H AT S U S TA I N S I T S S T R U C T U R E

Movement drives cerebral perfusion and neurotrophic signalling, and is associated with the maintenance of grey matter volume.

III — SLEEP W H E N T H E B R A I N C L E A R S A N D C O N S O L I D AT E S

Sleep architecture governs memory consolidation and the overnight clearance of metabolic by-products.

IV — CARDIOVASCULAR HEALTH W H AT T H E B R A I N R E C E I V E S

The brain is a vascular organ. Blood pressure, lipids and vessel integrity determine its supply — and appear in imaging as white matter change.

V — IMMUNE HEALTH W H A T Q U I E T LY E R O D E S I T

Chronic low-grade inflammation is among the most consistent correlates of accelerated brain ageing.

M E A S U R ED TO G E TH ER Not one at a time. The determinants interact. Poor sleep raises inflammation; inflammation impairs vascular function; vascular change alters cognition. Brain Potential assesses and addresses all five in a single week.

Brain Potential Program

BR AIN POTENTIAL IS NOT A MEMORY TEST. IT IS A CLINICAL READING OF YOUR BR AIN’S TR AJECTORY. Cognitive questionnaires tell you how you performed on a Tuesday morning. They cannot tell you what your brain looks like, what is driving the result, or where the curve is heading.

Brain Potential measures the substrate — brain volume, white matter integrity, vascular status, inflammatory and metabolic biology, genomic ageing markers — and then intervenes across all five determinants under continuous medical supervision. Seven days in Montreux, followed by a protocol designed to continue for years.

MEASURED

MEDICAL

LASTING

I M A G E D, N OT E S T I M AT E D

N E U R O LO GYL E D, P H Y S I C I A N SUPERVISED

A P R OTO CO L T H AT CO N T I N U E S

Brain volumetry and white matter analysis from MRI. Genomic ageing markers, glycans, ceramides, inflammatory and metabolic panels.

You leave with your brain quantified, not your symptoms discussed.

A brain specialist, a cardiologist, a psychologist, a neuro-nutritionist — coordinated by your referring physician.

Cognitive training calibrated to your profile and continued at home through the Clinique La Prairie app, proprietary brain formulas, and structured follow-up.

Swiss clinical standards, applied to cognition.

A trajectory changes over years, not days.

Edition August 2026

THE CLP LONGEVIT Y METHOD. A CONTINUOUS CYCLE, REFINED SINCE 1931.

Every Clinique La Prairie program — Brain Potential included — is built on the exclusive CLP Longevity Method. A continuous five-step cycle designed to make longevity personal, measurable and actionable.

I — IN-DEPTH ASSESSMENT & DIAGNOSTICS Every journey begins with the Longevity Master Assessment™ (LMA) — a comprehensive screening of more than 300 biomarkers, assessing the most fundamental longevity drivers for a complete understanding of one’s own biology.

II — CLP PREDICTIVE APPROACH Your data is integrated with predictive algorithms to forecast the pace at which you are ageing and the health risks most relevant to your trajectory.

III — ULTR A-CUSTOMIZED SOLUTIONS Predictive insights form the foundation of your stay. A bespoke set of longevity interventions is selected to match your needs, your aspirations and your priorities.

IV — INTERVENTION ACROSS FOUR PILLARS Your program is delivered through the four pillars of longevity — Medical, Nutrition, Movement and Wellbeing — drawing on proprietary protocols developed over decades to anticipate and address age-related risks before they manifest.

V — CONTINUOUS MEASUREMENT Longevity is a long-term commitment. Before, during and after your stay, we measure how your biomarkers evolve — shaping your trajectory and empowering you to manage your longevity capital over time.

Brain Potential Program

EVERY TR ANSFORM ATION BEGINS WITH DATA. THIS ONE BEGINS WITH AN IM AGE. At the heart of every Clinique La Prairie program lies the Longevity Master Assessment™ (LMA) — a proprietary set of advanced screenings measuring more than 300 biomarkers, available exclusively at Clinique La Prairie.

Brain Potential adds a layer no other longevity program carries: direct structural imaging of the brain, read with software that quantifies what a radiologist’s report describes.

BR AIN VOLUMETRY DOES NOT TELL YOU HOW YOU FEEL TODAY. IT TELLS YOU WHERE YOU SIT ON A CURVE.

Edition August 2026

B E YO N D T H E L M A — T H E B R A I N L AY E R

BRAIN V O LU M E T R Y MRI, QUANTIFIED

W H I T E M AT T E R HYPERINTENSITIES T H E VA S C U L A R S I G N AT U R E

C A R D I O VA S C U L A R ASSESSMENT S U P P LY, M E A S U R E D

B R A I N H E A LT H SCREENING T H E B I O LO G Y B E N E AT H

GENOMIC & E X C LU S I V E M A R K E R S PREDISPOSITION AND I N F L A M M AT I O N

COGN ITIVE PROFILING FUNCTION, MAPPED

Changes in brain volume are valuable biomarkers of clinical state.

Data from magnetic resonance imaging is processed by our exclusive neuroimaging software. Quantib volumetric method for guests over 40; classic brain MRI under 40.

White matter lesions which, in larger volumes, have been associated with brain atrophy and cognitive decline — and which reflect the cardiovascular determinant made visible.

Cardiologist consultation, stress test, electrocardiogram and risk score. Chest CT with calcium scoring where clinically indicated.

Blood analysis of inflammation markers, fatty acids and heavy metals — providing key insights into the environment in which your neurons are working.

Precision Longevity Gene Aging DNA test. Glycans screening — the Chronic Inflammation Score available worldwide only at Clinique La Prairie. Ceramides screening using CERT2 patented technology.

Memory recall, executive function, processing speed, visuospatial function and attention — assessed to establish your cognitive profile and identify where training will do most.

Brain Potential Program

EXCLUSIVE SOLUTIONS, PROPRIETARY TO CLINIQUE LA PR AIRIE. Four proprietary formulations, developed through nutrigenomic science and available nowhere else in the world.

U LT I M A T E N O O T R O P I C B L E N D

The first comprehensive, science-based nootropic formula with ingredients selected exclusively to support brain health. It supports and modulates cognitive performance and neuronal protection, and builds resilience to physical and mental stress — and, consequently, aids physical performance and recovery.

C L P C E L L U L A R G E N O M I C B R A I N H E A LT H

A health complex unique to Clinique La Prairie, developed to achieve the optimum daily dose for cognitive support and the restoration of circadian rhythms and homeostasis. Three specifically focused nutrigenomic dietary supplements that work in synergy.

C L P D A I LY P R O T E C T C O M P L E X T R E A T M E N T

An advanced nutraceutical formulation providing cellular protection and functional support, with a focus on cognition, antioxidant defence, anti-inflammatory potential, metabolic support and stress release. A blend of plant extracts and bioactive compounds supporting the body’s dynamics across the day.

Edition August 2026

C L P D A I LY S L E E P & R E L A X A T I O N C O M P L E X

A broad-spectrum formulation of sleep-modulating and calming plant extracts, adaptogenic and relaxation-inducing, designed to restore sleep homoeostasis and biological rhythms — because sleep is where the brain consolidates and clears.

LO N G E V IT Y H ER BA L I N FU S I O N

A science-based herbal tea blend selected to support the body and help counter inflammation — a daily ritual that transitions seamlessly into the evening nutraceutical regimen.

Brain Potential Program

MONTREUX, SWITZERL AND WHERE THE SCIENCE WAS MADE.

Brain Potential is delivered at Montreux alone. This is not a limitation — it is a condition of the program.

The neuroimaging capability, the volumetric analysis software and the neurological expertise the model requires exist here, and the laboratory where that model was developed is thirty minutes along the lake. Clinique La Prairie’s historical home, on the shore of Lake Léman with the Alps behind. The flagship — where nearly a century of Swiss longevity science was developed, and where the Brain Potential program was conceived.

Here the setting is alpine: still water, mountain air, the discipline of Swiss landscape. The atmosphere is one of quiet precision — and the environment itself contributes, through sleep, movement and stillness, to the determinants the program is built on.

Rue du Lac 142 — 1815 Clarens-Montreux, Switzerland

W H AT M O N T R E U X M A K E S POSSIBLE

― Brain MRI with volumetric and white matter analysis, read by our exclusive neuroimaging software. ― Direct proximity to the Laboratory for Research in Neuroimaging at CHUV, Lausanne. ― A brain specialist, cardiologist, psychologist and neuronutritionist under one roof. ― Chest CT with calcium scoring and full cardiovascular assessment on site. ― Alpine forest and lakeside paths for the movement and nature components of the protocol.

Edition August 2026

Brain Potential Program

W H AT I S I N C LU D E D

THE BR AIN POTENTIAL PROGR AM. IN FULL. Across the four interconnected CLP pillars — Medical, Nutrition, Wellbeing and Movement — every element is delivered under continuous physician supervision.

LO N G E V I T Y B R A I N M ED I C A L T E C H N O L O G I E S & C O N S U LTAT I O N S › LMA: Advanced laboratory tests › LMA: Precision Longevity – Clinique La Prairie exclusive Gene Aging DNA Test › LMA: Glycans screening, exclusively available at Clinique La Prairie › LMA: Ceramides screening, exclusively available at Clinique La Prairie › Longevity consultations and week-long follow-up by your leading physician › Chest CT scan with calcium scoring** › Brain MRI – analysis of brain volumetry and morphology (For patients after 40 years – brain MRI with Quantib method, for patients younger than 40 years – classic brain MRI)**

› One brain specialist consultation › A cardiovascular assessment, including: ― Consultation with the cardiologist ― Stress test ― Electrocardiogram › Cognitive assessment and stimulation: test, expert-led training sessions during stay and continued in a follow-up plan › One psychology session – stress management with cardiac coherence therapy

Edition August 2026

CUTTING-EDGE SCIENCE

WELLBEING

› CLP Cellular Genomic Brain Health*

› LMA: One Wellbeing Index Assessment, aimed at evaluating both physical and mental wellbeing

› HP Cellular Active

NEURO-NUTRITION › LMA: One Nutrition Index Assessment, a CLP proprietary tool that provides a unique insight into your nutritional strengths as well as your potential areas of improvement › LMA: DNA microbiota test and probiotic cure based on the results, discussed with the nutritionist during a remote follow-up consultation after the stay › One “Unlocking Longevity” consultation to develop a personalized nutritional plan based on medical results and nutrition index assessment › Exclusive CLP Daily Protect Complex Treatment* › Exclusive CLP Daily Sleep & Relaxation Complex Treatment* › Exclusive CLP Daily Ultimate Nootropic Blend Treatment* › Daily Longevity Herbal Infusions › Clinique La Prairie anti-inflammatory menus

› Four sessions of low-frequency vibration therapy – the most innovative technology in sound therapy › One Facial treatment by La Prairie › One head, neck, and shoulders massage › One Chi Nei Tsang massage

MOVEMENT › LMA: One Movement Index Assessment, to comprehensively evaluate physical functionality, neuro-muscular health and mobility, to ultimately optimize longevity through targeted exercise › One Personalized Moving & Brain session › One breathing session with moonbird device for breathing protocol › One outdoor hiking activity

FO L LOW - U P › Brain stimulation sessions follow-up

*CLP proprietary scientific solutions **These examinations will be carried out only after initial evaluation with your referring doctor and based on your age, medical history and overall health status.

Brain Potential Program

ONE PROGR AM. SEVEN DAYS THAT ESTABLISH A BASELINE.

D E S T I N AT I O N S

Montreux, Switzerland

D U R AT I O N

7 days, 6 nights — arrival Sunday, departure Saturday.

D E S I G N E D FO R

Individuals experiencing memory lapses, reduced focus, mental fatigue or slower recall — those with a family history of cognitive decline, and those in high cognitive demand who want their brain health measured while it is most responsive to change.

I N CLU D ES

Full access to the fitness and wellness centres, including swimming pool, sauna, steam room, zero-gravity floating bed and vitality pool. Ongoing medical supervision. Personalized program and continuity protocol.

PRICE

From 28,400 CHF (superior room) Service charge and VAT included. Prices indicative; final quotation provided upon booking based on accommodation category and season.

Edition August 2026

Brain Potential Program

Edition August 2026

READY TO BEGIN? SPEAK WITH YOUR CLP ADVISOR Every Brain Potential journey begins with a private consultation.

Your dedicated advisor will confirm dates and accommodation, and review with our medical team which imaging and cardiovascular examinations are appropriate to your age, medical history and health status before your arrival. reservation@cliniquelaprairie.com +41 21 989 34 07 cliniquelaprairie.com

M EM ORY I S N OT TH E M E A S U R E. T R A J EC TO RY I S .