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Referencias 1. Adzick NS. Flake AW, et al. Management of congenital lung lesions. Semin Pediatr Surg 2003;12:10-6 2. Adzick, M.D., Elizabeth A. Thom, Ph.D., et al. A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele N Engl J Med 2011;364:993-1004. 3. American Academy of Pediatrics. Committee on genetics. Folic acid for the prevention of neural tube defects. Pediatrics 1999; 104: 325-327. 4. Aubard Y, Derouineau I, Aubard V et al. Primary fetal hydrothorax: a literature review and proposed antenatal clinical strategy. Fetal Diagn Ther 1998; 13: 325–333. 5. CDC. Use of folic acid for prevention of spina bifida and other tube defects, 1983-1991. MMWR 1991; 40: 513-515. 6. Deprest J, Nicolaides K, Gratacos E. Fetal surgery for congenital diaphragmatic hernia is back for never gone. Fetal Diagn Ther 2011:29:6-17. 7. Deprest J, Gratacos E, Nicolaides KH, et al. Fetoscopic tracheal occlusion (FETO) for severe congenital diaphragmatic hernia: evolution of a technique. Ultrasound Obstet Gynaecol 2004; 24:121–126. 8. Donoso S, E. ¿Está aumentando la mortalidad perinatal en Chile? Rev Chil Obstet Ginecol 2011; 76(6): 377 – 379 9. Freedman AL, Johnson MP, Smith CA, et al. Long-term outcome in children after antenatal intervention for obstructive uropathies. Lancet 1999; 354: 374–377. 10. Jani J.C, Peralta C.F.A and Nicolaides K. Lung-to-head ratio: a need to unify the technique. Ultrasound Obstet Gynecol 2012; 39: 2–6 11. Jani JC, Nicolaides KH, Grataco's E, et al., Deprest JA. Severe diaphragmatic hernia treated by fetal endoscopic tracheal occlusion.Ultrasound Obstet Gynecol 2009; 34: 304–310. 12. Knox EM, Kilby MD, Martin WL, et al. In-utero pulmonary drainage in the management of primary hydrothorax and congenital cystic lung lesion: a systematic review. Ultrasound Obstet Gynecol 2006;28:726-34 13. Nazer, Julio. Cifuentes, Lucía. Malformaciones congénitas en Chile y Latino América: Una visión epidemiológica del ECLAMCdel período 1995-2008.Rev Med Chile 2011; 139: 7278 14. Ruano, R; C. T. Yoshisaki, M. M. Da Silva, M. E. et al. A randomized controlled trial of fetal endoscopic tracheal occlusion versus postnatal management of severe isolated congenital diaphragmatic hernia. Ultrasound Obstet Gynecol 2012; 39: 20–27. 15. Ruano R (MD, PhD); Peiro (MD) JL; Da Silva MM (MD, PhD); et al. Early fetoscopic tracheal occlusion for extremely severe pulmonaryhypoplasia in human isolated congenital diaphragmatic hernia:preliminary results. Ultrasound Obstet Gynecol. 2013 Jan 24. Doi: 10.1002/uog.12414. [Epub ahead of print] 16. J Verbeek, Heep, Maurits, Cremee,W Hoving, et al. Fetal endoscopic myelomeningocele closure preserves segmental neurological function.Developmental Medicine & Neurology 2012, 54: 15-22.

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