CCMX Annual Activity Report 2010 by CCMX

ANNUAL ACTIVITY REPORT 2010

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Annual Activity Report 2010

Contents How to be Involved With CCMX ?

Learning With CCMX

Outreach and Networking Activities

The Research We Focus On

Valuable Insight into Internal Structure and Properties

Tracking Down Metallurgical Phenomena

Defect Formation in the Spotlight

Nanoparticles — Put to the Acid Test

3D Tissue Imaging for ‘Nanomedicine’

New Ground for Materials Science and Medical Technology

2010 Peer Reviewed Publications

2010 Data

Projects funded in 2010

CCMX Team

Annual Activity Report 2010

Message from the Chair

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Annual Activity Report 2010

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T"5'&8&(7/

Professor Karen Scrivener Chair CCMX

Photos by Tony Kunz

How to be Involved With CCMX

Knowledge transfer and networking opportunities are an important aspect of CCMX events.

Research

Education and Training

Outreach Activities

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Annual Activity Report 2010

Learning With CCMX 2010 was an active year for education and training, with more than 160 participants in five courses and workshops, bringing together PhD students, engineers, and scientists from industry and academic institutions in a variety of settings.

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Annual Activity Report 2010

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Photos by Stefanie Lischer, Empa

«I really took advantage of the course, not only for the technical knowledge but also to make new contacts for possible future collaborations». EPFL participant in the CCMX Summer School “The workshop gave a good overview of experimental techniques available to characterise materials at the nanoscale”. Participant in a CCMX Workshop

2010 Programme of CCMX Courses Date

Course

Title

3 June

CCMX Workshop

Nanoscale analytics of materials for industrial application

6–8 July

CCMX Continuing Education Course

Powder Characterisation: From nanometers to millimeters and from theory to practice

25–27 August

CCMX Summer School

Advanced Characterisation Techniques in Materials

29 September – 1 October

CCMX Continuing Education Course

Advanced X-ray diffraction methods for coatings: Strain, defects and deformation analysis of thin films

5–12 November

CCMX Continuing Education Workshop

Travelling Lab Workshop: Materials for Life Sciences

“After several years working in the industry it was good having a refresh. When you are studying it is not always easy to understand exactly what use you will be able to make of the theory you are learning. This course will allow me to better understand the results of the materials characterisation that we subcontract to outside companies”. Industry participant in the CCMX Summer School Annual Activity Report 2010

Outreach and Networking Activities The ‘Technology Aperitifs’ are a series of events held throughout the year at which CCMX provides information on hot topics related to materials science, encourages creativity for future applications, and allows contacts for partnerships in a pleasant networking environment. !$&5%g68*%g;5<F;"*#/%65%&P>&8#%)5%&54"8)5C 3&5#6(%*;*#6"56B"("#7%6#%Z&*#(h/%')33&5#*% )5%$)E%#$&%')3>657%;*&*%g"+&%07'(&%D**&**C 3&5#%bg0Dc%6*%6%*#86#&="'%#))(%#)%3&&#%"#*% &54"8)53&5#6(%*;*#6"56B"("#7%')33"#3&5#/% $&%'65%B&%*;8&%)+%+"5<"5=%65%6##&5#"4&% 6;<"&5'&i%D#%Z&*#(h/%*;*#6"56B"("#7%3&65*% 6<)>#"5=%>86'#"'&*%#$6#%$&(>%#$&%')3>657% #)%3&&#%#$&%5&&<*%)+%#$&%>8&*&5#%E"#$);#% ')3>8)3"*"5=%#$&%E)8(<j*%6B"("#7%#)%*6#"*+7% #$&%<&365<*%)+%#$&%+;#;8&?%g0D%"*%6%*#86#&="'% #))(/%65<%"*%"5#&=86#&<%6*%6%*7*#&36#"'%<&'"*")5% *;>>)8#%#))(%"5%#$&%"55)46#")5%65<%8&5)46#")5% >8)'&**%"5%#$&%+6*#C3)4"5=%')5*;3&8%=))<*% *&'#)8/%6*%E&((%6*%+))<%>6'I6="5=%&')C<&*"=5% ;*"5=%AQkJK%bA6'I6="5=%Q3>6'#%k;"'I%J46C (;6#")5%K))(c?%K$&%<&*"=56#&<%)BG&'#"4&%)+%g0D% "*%#)%+6'"("#6#&%')33;5"'6#")5%#$8);=$);#% #$&%*;>>(7%'$6"5%65<%8&<;'&%')3>(&P"#7/% ')*#/%65<%')5+;*")5?

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Annual Activity Report 2010

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Technology Aperitifs — Time to Meet the Experts

Photos by Nathalie Jongen, CCMX

2010 CCMX Outreach and Networking Actvities

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Date

Title

23 March 2010

Technology Aperitif “ Life Cycle Assessment of Materials”

28 April 2010

CCMX Annual Meeting

8 June 2010

Technology Aperitif “Materials for Energy Applications”

20 October 2010

Technology Aperitif “Mechanical Properties of Materials”

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Photo by Nathalie Jongen, CCMX

The Research We Focus On

Research expenditures by research area (%) Neo-metallurgy

17 %

Modelling of Metallic Systems Engineered Biomaterials

23 % 12 %

Anti-microbials + Anti-inflammatory Materials and Surfaces Nanomaterials and Safety Aspects Analytical Platform

Fostering Public-Private Partnerships

What is pre-competitive research?

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Annual Activity Report 2010

Members from the industry identify priority research topics with CCMX K$&%_&*&68'$%K"'I&#%A8)=8633&%6(()E*% +(&P"B"("#7%+)8%')3>65"&*%)+%<"++&8&5#%*"l&*% #)%>68#"'">6#&%"5%#$&%8&*&68'$%6'#"4"#"&*%)+%#$&% 0&5#8&?%0)3>65"&*%#6I&%6%(&6<%"5%"<&5#"+7"5=% #$&%>8")8"#7%8&*&68'$%#)>"'*%65<%367%"5+(;&5'&% #$&%'$)"'&%)+%8&*&68'$%>8)G&'#*%#)%B&%'688"&<% );#%E"#$"5%6%#$&36#"'%8&*&68'$%68&6?%Z)#%

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Photo by Antonia Neels, CSEM Photo by Nathalie Jongen, CCMX

Companies involved in 2010 in projects (22) Alphabetical order

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')5'&85%#$&%&P>()"#6#")5%)+%&P"*#"5=% 656(7#"'6(%#&'$5"F;&*%+)8%565)*'6(&% 656(7*"*%"5%5&E%+"&(<*%)+%6>>("'6#")5?% 0)C+;5<"5=%+8)3%"5<;*#8"6(%>68#5&8*% 65<H)8%)#$&8%"5*#"#;#")5*%"*%6%I&7%6*>&'#% )+%#$&*&%>8)G&'#*?

• ABB Turbo Systems • Alstom • Alcan • AO Foundation • Asulab • Attolight • BASF • IG DHS • ION-TOF Technologies • Kugler Bimetal • Lovalite • Lyncee Tec • Novelis • OPEA • RMS Foundation • Rolex • Sika • Straumann • Swissnuclear • VV SA Varinor • Wessling • YXLON International X-Ray GmbH.

Other entities involved in 2010 (2) • Federal Office for Public Health • Federal Office for the Environment

Annual Activity Report 2010

Valuable Insight into Internal Struct What are the crucial features of composition and structure of a material allowing a particular preparation, a study of properties, an exciting new development and directed reproduction? Characterisation is the key to seeing into materials. That is why CCMX created MaCH2, an analytical equipment database, tailored to the requirements of Swiss industry. g&+#r%K)3)=86>$"'%8&')5*#8;'#")5%)+%65%"8)5C)P"<&%565)*#68s%6>>8)P"36#&%+863&% *"l&%)+%.U-%53?%T63>(&%');8#&*7%)+%M8?%D?%]86;5%65<%M?V?%])86/%J3>6? ])##)3r%D#)3"'%8&*)(;#")5%*'655"5=%#865*3"**")5%&(&'#8)5%3"'8)=86>$*%)+%65% &<=&%)+%6%g"C')5<;'#"5=%Z<g"K"@n DSZTUBM XIJMF UIF EBSL Ă FME NJDSPHSBQI MFGU >8)4"<&*%65%"36=&%)+%#$&%$&647%'6#")5*%')5#6"5"5=%"5+)836#")5%6B);#%#$&%8&)8C HBOJTBUJPO PG UIF /E BU UIF WFSZ TVSGBDF UIF CSJHIU Ă FME NJDSPHSBQI SJHIU SFWFBMT #$&%()'6#")5%)+%)P7=&5%46'65'"&*%6*%+6"5#%B;#%<"*#"5'#%B8"=$#%*>&'I(&*?%T'6(&%B68%"*% ,%53?%0);8#&*7%)+%J3>6?

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Annual Activity Report 2010

Z&;'$a#&(/%65<%#$&%J(&'#8)5%1"'8)*')>7% JKL%"5%[;8"'$?%160L,%36I&*%"#%&6*7%#)%+"5<% #$&*&%'&5#&8*%65<%#)%')3>68&%#$&"8%+"&(<*% )+%&P>&8#"*&?

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Empa: Correlation of structure and function

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ure and Properties

Acc. V

Spot Magn

Det WD

Exp

10.0 kV

4.0 15000 x

TLD 4.8

MaCH 2

2 µm

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Annual Activity Report 2010

Valuable Insight into Internal Structure and Properties ^"=%,%t%_&*;(#%)+%JM2%&(&3&5#% 36>>"5=s%#$&%')5'&5#86#")5% PG UISFF EJÆ&#x2030; FSFOU FMFNFOUT

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Annual Activity Report 2010

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MaCH 2

54.00 µm = 90 steps IPF [001] 56.00 µm = 80 steps Unique Grain Color

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52.00 µm = 80 steps IPF [001]

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Annual Activity Report 2010

Tracking Down Metallurgical Phenom CCMX supports research in metallurgy in order to improve the modelling of metallic systems and to develop new alloys and processes. This applicationdriven research is conducted via collaborations between universities and research institutes in the ETH Domain. Industry reaps a two-fold benefit from this cooperation: companies not only acquire new knowledge in the form of novel products, but they also have access to materials science engineers who have followed a state-of-the-art educational programme.

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Annual Activity Report 2010

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Defect Formation in the Spotlight Scientists from EPFL and the Paul Scherrer Institute (PSI) are combining modelling techniques and X-ray tomographic microscopy to penetrate the secrets of defect formation in solidification processes. Their innovative approach is the key to a deeper understanding of materials structure and properties.

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1"'8)>)8)*"#7%65<%$)#%#&68"5=%68&%#E)% 36G)8%<&+&'#*%"5%*)("<"+"'6#")5%>8)'&**&*?% K$"*%"*%E$7%#$&%#&63%6#%JA^gj*%0)3>;#6C #")56(%16#&8"6(*%g6B)86#)87%bgT12c/%$&6<&<% B7%A8)+?%1"'$&(%_6>>6l/%68&%*&&I"5=%6%B&##&8% ;5<&8*#65<"5=%)+%*;'$%<&+&'#%+)836#")5% #$8);=$%6%')3B"5&<%3)<&(("5=C&P>&8"C 3&5#6(%6>>8)6'$?% Q5%#$&%+"8*#%>68#%)+%#$"*%>8)G&'#/%#$&%8&*&68'$&8*% 68&%<&4&()>"5=%6%3;(#">$6*&C+"&(<%3)<&(% "5')8>)86#"5=%#$8&&%>$6*&*%p%*)("</%("F;"</% 65<%=6*%p%"5%)8<&8%#)%<"8&'#(7%<&*'8"B&%#$&% 3)8>$)()=7%)+%3"'8)>)8&*%')5*#86"5&<%#)% =8)E%"5%6%*)("<%5&#E)8I?%^"8*#%<&4&()>&<% 65<%#&*#&<%"5%,M%+)8%*"3>(&%*)("<%=&)3&#87/% #$"*%3)<&(%6'');5#*%+)8%#$&%';846#;8&%)+% #$&%>)8&*%6*%E&((%6*%+)8%=6*%<"++;*")5?%K$&% 6"3%E6*%#)%36I&%6%<"8&'#%')3>68"*)5%E"#$%

Annual Activity Report 2010

656(7#"'6(%>)8&%>"5'$"5=%3)<&(*%646"(6B(&% "5%#$&%("#&86#;8&?%K$&%3)<&(%E6*%#$&5% &P#&5<&<%#)%nM?%K)%)4&8')3&%#$&%$"=$% ')3>;#6#")56(%')*#/%6%5&E%>686((&("l&<% ')3>;#&8%')<&%E6*%<&4&()>&<%#)%<"*#8"B;#&% #$&%'6(';(6#")5*%)4&8%6%;*&8C*>&'"+"&<% 5;3B&8%)+%>8)'&**)8*?%K$&%8&*;(#*/%)B#6"5&<% "5%#$&%')5#&P#%)+%6%A$M%#$&*"*/%*$)E%#$6#% #$&%>$6*&%+"&(<%3)<&(%"*%'6>6B(&%)+% <&*'8"B"5=%#$&%>)8&%3)8>$)()=7%"5%B)#$% ,M%65<%nM?%!"#$%#$&%$&(>%)+%#$&%nM%3)<&(/% W>"5'$"5=%&++&'#*X%p%"5'8&6*&%"5%>)8&% ';846#;8&%<;&%#)%("3"#&<%4)(;3&%(&+#%B7% 6%*)("<%p%'65%B&%"54&*#"=6#&<%"5%6%3)8&% 8&6("*#"'%E67?%1)8&)4&8/%#$&%nM%')<&%E"((% =&5&86#&%8&*;(#*%&56B("5=%<"8&'#%')3>68"*)5*% #)%B&%36<&%E"#$%2C867%#)3)=86>$"'%3"'8)C *')>7%<6#6%)B#6"5&<%6#%ATQ/%E"#$"5%#$&%=8);>% )+%A8)+?%168')%T#63>65)5"/%$&6<%)+%#$&%

2C867%K)3)=86>$7%d8);>%6#%#$&%TE"**% g"=$#%T);8'&%bTgTc?%T;'$%<6#6%>8)4"<&*%B)#$% #$&%"5>;#*%+)8%#$&%6'#;6(%*)("<%=&)3&#87%+)8% >)8&%'6(';(6#")5*%65<%';846#;8&%&*#"36#")5*% +)8%46("<6#"5=%#$&%'6(';(6#")5*?%W]6*&<%)5% #$"*%&P>&8"3&5#C3)<&(("5=%6>>8)6'$/%E&% 68&%#87"5=%#)%<&8"4&%*"3>("+"&<%656(7#"'6(% *)(;#")5*%+)8%>)8&%>"5'$"5=%&++&'#*%#$6#% '65%B&%;*&<%"5%6%36'8)*'6(&%3)<&(%)+%>)8&% +)836#")5X/%')5'(;<&*%A8)+?%_6>>6l? Q5%#$&%*&')5<%>68#%)+%#$&%>8)G&'#/%#$&%*'"&5#"*#*% $64&%'$)*&5%6%=865;(68%<7563"'%6>>8)6'$% #)%3)<&(%$)#%#&68"5=%+)836#")5%"5%*)("<"+7"5=% 6(()7*/%6%<&+&'#%#$6#%*$68&*%*"3"(68"#"&*%E"#$% *$8"5I6=&C"5<;'&<%3"'8)>)8)*"#7%p%*;'$% 6*%6%(6'I%)+%("F;"<%+&&<"5=%p%B;#%"5%#$"*%'6*&% "5<;'&<%B7%#&5*"(&%*#8&**&*%"5%#$&%')$&8&5#% *)("<%5&#E)8I?%Q5%)8<&8%#)%6'');5#%+)8%#$&%

MERU

Liquid

Water cooling

mush

Solid

]&()Er%D%>)8&%=8)E5%B&#E&&5%*>$&8"'6(%*)("<% =86"5*%68865=&<%"5%6%';B"'%5&#E)8I?%!$"(&%#E)%)+% #$&%&"=$#%*)("<%=86"5*%b8&<c%68&%6#%=*%x%-?Y/%#$&%>)8&% $6*%>&5&#86#&<%"5%68&6*%B&#E&&5%#$&%*)("<%=86"5*?

Casting speed

4 mm

_"=$#r%,M%L)#%K&68%T"3;(6#")5*

Q36=&*%');8#&*7%)+%JA^g?

Bottom block

Pressure (pa) 0.00 -1.0e + 005 -2.0e + 005 -3.0e + 005 -4.0e + 005 -5.0e + 005

()'6("*6#")5%)+%*#8&**&*%65<%("F;"<%+&&<"5=% 6#%$"=$%*)("<%+86'#")5/%6%_&>8&*&5#6#"4&% e)(;3&%J(&3&5#%b_eJc%)+%#$&%*)("<"+7"5=% 6(()7/%#7>"'6((7%"5'(;<"5=%)4&8%6%#$);*65<% =86"5*/%"*%')5*"<&8&<?%K$&%nM%3)<&(%#$&5% ')5*"*#*%)+%6%*)("<"+"'6#")5%3)<;(&/%6% 3&'$65"'6(%3)<;(&%p%6%nM%*&3"C*)("<% <&+)836#")5%3)<&(%B6*&<%)5%6%')3B"5&<% M"*'8&#&H^"5"#&%J(&3&5#%6>>8)6'$%p%65<% 6%+(;"<%+()E%3)<;(&?%\*"5=%6%e)8)"5)w%#&**&(C (6#")5%)+%865<)3(7%<"*#8"B;#&<%5;'(&6#")5% '&5#8&*/%#$&%*)("<"+"'6#")5%3)<&(%=&5&86#&*% 6%*&#%)+%"5#&8')55&'#&<%#8"65=;(68%&(&3&5#*/% 8&>8&*&5#"5=%#$&%"5#&8=865;(68%("F;"<%'$65C 5&(%&(&3&5#*%()'6#&<%B&#E&&5%>68#"6((7% ')$&8&5#%=86"5*%6>>8)P"36#&<%B7%6%*&#%)+% >)(7$&<8)5*?%K$&%<&+)836#")5%)+%#$&%*)("<% "*%#$&5%'6(';(6#&<%;*"5=%#$&%DB6F;*b_c% *)+#E68&/%#$;*%="4"5=%6''&**%#)%#$&%)>&5"5=*%

b'()*;8&*c%)+%=86"5%B);5<68"&*?%0)3B"5&<% E"#$%*)("<"+"'6#")5%*$8"5I6=&/%#$"*%#$&5% &56B(&*%#$&%"5<;'&<%"5#&8=865;(68%+(;"<% +()E%#)%B&%'6(';(6#&<%;*"5=%*>&'"+"'6((7% <&4&()>&<%*)+#E68&?%W!&%68&%6#%#$&%+"56(% *#&>%)+%"#&86#"4&(7%');>("5=%#$&%+(;"<%+()E% 3)<&(%65<%#$&%*&3"C*)("<%<&+)836#")5% 3)<&(X/%*67*%_6>>6l?%WL&5'&/%E&%E"((% #$&5%;*&%#$&%=865;(68%$7<8)C3&'$65"'6(% ');>("5=%#)%>8&<"'#%65<%B&##&8%;5<&8*#65<% #$&%+)836#")5%)+%()'6("l&<%$)#%#&68*?X% K$&%$)#%#&68"5=%3)<&(%$6*%B&&5%6>>("&<% #)%#$&%M0%'6*#"5=%)+%8);5<%B"((&#*%"5%)8<&8% #)%*&&%E$&#$&8%&P>&8"3&5#6((7%)B*&84&<% <&+&'#*%'65%B&%8&>8)<;'&<%p%3&65"5=/% #$&%+)836#")5%)+%#$8&&%';84&<%B865'$&*% E"#$%6**)'"6#&<%3"'8)'86'I*%6#%#$&%'&5#8&% )+%#$&%B"((&#%E$&5%#$&%'6*#"5=%*>&&<%"*% "5'8&6*&<?%

Q5%6<<"#")5%#)%&P%*"#;%2C867%#)3)=86>$7% '$686'#&8"*6#")5%>&8+)83&<%6#%ATQ/%6%5&E% *&#C;>%+)8%#$&%"5%*"#;%)B*&846#")5%)+%3"'8)C *#8;'#;8&%65<%<&+&'#%+)836#")5%"*%B&"5=%B;"(#% )5%#$&%TgT%K@10DK%B&63("5&?%T;'$%<"8&'#% )B*&846#")5*%68&%'8"#"'6(%+)8%6%B&##&8%;5<&8C *#65<"5=%)+%*)("<"+"'6#")5%>$&5)3&56?%K$&% *'"&5#"*#*%"54)(4&<%"5%#$"*%>8)G&'#%$64&%<&4"*&<% 6%3)<&86#&C%#)%$"=$C#&3>&86#;8&%+;856'&% 36<&%)+%#E)%<")<&%(6*&8*%bN9-%53%E64&C (&5=#$c/%&6'$%E"#$%.U-%!%)+%>)E&8/%*733&#8"C '6((7%"5*#6((&<%)5%&6'$%*"<&%)+%#$&%2C867%B&63?% _&'&5#(7%8&'&"4&<%6#%ATQ/%#$"*%#E)C(6*&8%*7*#&3% +;856'&%E"((%6(()E%#$&%*'"&5#"*#*%E)8I"5=%"5%#$"*% 0012%>8)G&'#%#)%)B*&84&%"5%nM%5)#%)5(7%#$&% +)836#")5%)+%<&+&'#*/%B;#%6(*)%#$&%+)836#")5% )+%<&5<8"#&*%65<%)#$&8%3"'8)*#8;'#;8&*/%I&7% +6'#)8*%"5%;5<&8*#65<"5=%65<%"3>8)4"5=% *)("<"+"'6#")5%>8)'&**&*?

Annual Activity Report 2010

Nanoparticles – Put to the Acid Test In the CCMX project VIGO, the group headed by Professor Harald Krug at Empa, is developing a platform for evaluating the possible biological effects of nanoparticles. EPFL synthesises and characterises various types of nanoparticles, and this work shows that comprehensive particle characterisation is a prerequisite for understanding the behaviour of particles in

Photos by Elsbeth Heinzelmann

physiological media and their influence on test methods.

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Knowledge about nanoparticles a ‘must’ D(#$);=$%"5%565)#&'$5)()=7%p%367B&%3;'$% 3)8&%*)%#$65%"5%657%>6*#%#&'$5)()=7%p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d6((&5/%"5#&5<%#)%B8"<=&%

Annual Activity Report 2010

#$"*%=6>?%Q5%#$&%eQd@%>8)G&'#%#$&7%68&%<&4&()C >"5=%65%"5%4"#8)%&46(;6#")5%*7*#&3%#$6#%E"((% &P>()8&%#$&%+);8%I&7%6*>&'#*%)+%'7#)#)P"'"#7r% ""6B"("#7/%#5+(6336#")5/%$&5)#)P"'"#7%65<% %P"<6#"4&%*#8&**?%K$&%6"3%"*%#)%<&#&83"5&/% <&*'8"B&/%65<%')3>68&%#$&%>)#&5#"6(%B")C ()="'6(%&++&'#*%)+%565)>68#"'(&*%E"#$%6#%(&6*#% #E)%$"=$(7%*#65<68<"*&</%46("<6#&</%8&>8)C <;'"B(&/%65<%8&("6B(&%#&*#%3&#$)<*%+)8%&6'$% )+%#$&%+);8%&5<>)"5#*?%K$&%>(6#+)83%*$);(<% 6(()E%3&6*;8&3&5#*%E"#$%6%$"=$%<&=8&&%)+% 6'';86'7/%*&5*"#"4"#7/%65<%*>&'"+"'"#7/%65<%#)% '$686'#&8"*&%<"++&8&5#%565)36#&8"6(*%"5% #&83*%)+%#$&"8%*;8+6'&%'$&3"*#87/%>68#"'(&% *"l&%<"*#8"B;#")5/%*$6>&/%65<%'87*#6(("5"#7?%

Measuring viability Q5%6%+"8*#%*#&>/%#$&%*'"&5#"*#*%#;85&<%#$&"8%6##&5C #")5%#)%*;"#6B(&%4"6B"("#7%6**67*?%K)%#$"*%&5</% #$&7%"3>(&3&5#&<%')3>8&$&5*"4&%')5#8)(*% '6>6B(&%)+%6**&**"5=%565)36#&8"6(%"5#&8+&C 8&5'&%E"#$%>8)'&**&<%65<%;5>8)'&**&<% 1KT%6**67%8&6=&5#*?%WK$"*%6(()E&<%;*%#)% >8&C#&*#%&4&87%565)36#&8"6(%)+%"5#&8&*#%"5% #&83*%)+%;5<&*"86B(&%&++&'#*%"5<&>&5<&5#% )+%'&((;(68%8&6'#")5*X/%&P>(6"5*%M8%0)8<;(6%

L"8*'$/%6%>)*#<)'%B")()="*#%6#%J3>6?% WK)=&#$&8%E"#$%#$&%)>#"3"*&<%>(6#&%(67);#% 65<%>">&##"5=%*'$&3&/%#$"*%4"6B"("#7%6**67% 5)E%*&84&*%6*%65%6<&F;6#&%65<%+6*#% *'8&&5"5=%#))(%+)8%3&6*;8"5=%<)*&C 8&*>)5*&C';84&*%+)8%657%5)5C"5#&8+&8"5=% 565)36#&8"6(?X

Inflammation — natural reaction to infection _&=68<"5=%#$&%#)>"'%"5+(6336#")5/%#$&%J3>6% 8&*&68'$&8*%68&%'))>&86#"5=%E"#$%')((&6=;&*% +8)3%6((%)4&8%J;8)>&%"5%#$&%ZDZ@11\ZJ% >8)G&'#?%^;5<&<%B7%#$&%J;8)>&65%0)33"**")5/% #$"*%>68#5&8*$">%"*%')33"##&<%#)%6%')3>8&C $&5*"4&%6**&**3&5#%)+%&5="5&&8&<%565)C >68#"'(&*/%E"#$%6%>68#"';(68%+)';*%)5%&++&'#*% )5%#$&%"33;5&%*7*#&3?%D%>(6#&%(67);#%65<% 65%&P>&8"3&5#6(%*&#C;>%$64&%B&&5%'8&6#&<% #)%6<<8&**%565)36#&8"6(%"5#&8+&8&5'&%6#% *&4&86(%(&4&(*%)+%65%&5l73&C("5I&<%"33;5)C *)8B&5#%6**67%bJgQTDc?%D*%"5<"'6#&<%B7% >8&("3"5687%<6#6/%#$"*%6>>8)6'$%36I&*%"#% >)**"B(&%#)%<&#&'#%>)#&5#"6(%F;&5'$"5=% &++&'#*%)+%')();8&<%>68#"'(&*/%*"=56(%8&<;'#")5% <;&%#)%6==()3&86#")5%)8%6==8&=6#")5%

MatLife A

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Annual Activity Report 2010

3D Tissue Imaging for ‘Nanomedicine’ The German company ION-TOF GmbH and Basel University Hospital are working with Empa researchers in Dübendorf to develop a label-free sectioning apparatus for 3D tissue imaging. Based on a time-of-flight secondary ion mass spectrometer (TOF-SIMS), the Microtome4SIMS realized within a CCMX project is particularly suitable for analyzing biological samples

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Annual Activity Report 2010

Photo by Elsbeth Heinzelmann

with a view to creating nanoscale objects for medical use?

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Annual Activity Report 2010

Photo by Elsbeth Heinzelmann

New Ground for Materials Science

Experts in optoelectronic systems at CSEM are extending the capacity of x-rays by developing a system capable of reducing the exposure to radiation and producing much better contrast with enhanced image quality. Their innovation opens up new possibilities in materials science and medical technology.

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Annual Activity Report 2010

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Annual Activity Report 2010

2010 Peer Reviewed Publications SPERU

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2010 Peer Reviewed Publications

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2010 Data Use of funding in 2010 (KCHF) Funding of projects Education activities, conferences

149

Industrial liaison

141

Management & administration Total

4’307

Annual Activity Report 2010

403 5’000

Metrics for 2010 .Y%% .O%% .n% .v%% -?n%%

_;55"5=%>8)G&'#* A8)+&**)8*%"54)(4&<%"5%>8)G&'#* T&5")8%*'"&5#"*#*%b^KJc A)*#%<)'*%>6"<%B7%0012%b^KJc A)*#%<)'*%5)#%>6"<%B7%0012%b^KJc

.N% ..%% nv%% .4

A$M%*#;<&5#*%>6"<%B7%0012%b^KJc A$M%*#;<&5#*%5)#%>6"<%B7%0012%b^KJc A;B("'6#")5*%b>&&8%8&4"&E&<c Patents

Projects Funded in 2010

Principal Investigator (PI)

PI’s Institution

Other Institutions

ERU/ Platform

Viola Vogel

ETH Zurich

ETH Zurich, Empa

MatLife

Ralph Spolenak

ETH Zurich

EPFL, Empa, UNIZ

MatLife

Harald Krug

Empa

EPFL

MatLife

Marcus Textor

ETH Zurich

EPFL, Unispital Basel

MatLife

Stuart Holdsworth

Empa

ETH Zurich, PSI

MERU

Q5C*"#;%3&'$65"'6(%#&*#"5=

Helena Van Swygenhoven

PSI

Empa(2)

MERU

1)<&(("5=%)+%<&+&'#%+)836#")5%"5%*)("<"+"'6#")5%>8)'&**&*% ;*"5=%=865;(68%<7563"'*%65<%>$6*&%+"&(<%6>>8)6'$&*

Michel Rappaz / Alain Jacot

EPFL

Empa, PSI

MERU

Ralph Spolenak

ETH Zurich

PSI

MERU

g6B&(%+8&&%"36="5=%)+%3)(&';(68%6<*)8>#")5%)5%"5C*"#;% *;8+6'&C+;5'#")56(%>6##&85*

Nicholas Spencer

ETH Zurich

Empa

NMMC

Z65)*'6(&%8&*)(;#")5%)>#"'6(%3"'8)*')>7%+)8%36#&8"6(% "36="5=%65<%*>&'#8)*')>7

Christian Depeursinge

EPFL

EPFL, CSEM

NMMC

Davide Ferri

Empa

ETH Zurich, Empa

NMMC

Jean-Daniel Ganière

EPFL

ETH Zurich

NMMC

1"'8)#)3&vTQ1Tr%0$&3"'6(%#)3)=86>$7%)+%B")()="'6(% 36#&8"6(%E"#$%.--%53%8&*)(;#")5

Beat Keller

Empa

Unispital Basel

NMMC

D<6>#6#")5%)+%#$&%Z65)2DT%"5*#8;3&5#%#)%6%<&<"'6#&< B&63("5&%6#%#$&%TgT

Chistoph Quitmann

PSI

Empa

NMMC

M&4&()>3&5#%)+%6%2C867%>$6*&%')5#86*#%"5*#8;3&5#%+)8% #$&%'$686'#&8"*6#")5%)+%36#&8"6(*%E"#$%()E%6#)3"'%36**

Claus Urban

CSEM

Empa

NMMC

T75'$8)#8)5%>$6*&C')5#86*#%565)#)3)=86>$7%)+%+8&*$% 65<%$68<&5&<%'&3&5#"#");*%36#&8"6(*

Pietro Lura

Empa

EPFL, PSI

NMMC

Title of project T#;<7"5=%*"5=(&%'&((*%"5%&5="5&&8&<%nM%3"'8)&54"8)53&5#* 0)()8&<%'&863"'%*;8+6'&*%+)8%3&#6(("'%<&5#6(%"3>(65#*% 65<%>8)*#$&#"'%6>>("65'&* e?Q?d?@?%p%D%5&E%&46(;6#")5%#))(%+)8%<&#&83"56#")5/% <&*'8">#")5/%65<%')3>68"*)5%)+%#$&%B")()="'6(%&++&'#*%)+% 565)>68#"'(&*%H%565)36#&8"6(* T&88;(6#65&CB6*&<%65#"3"'8)B"6(%*;8+6'&%>(6#+)83* J4)(;#")5%)+%3"'8)*#8;'#;8&%65<%3&'$65"'6(%8&*>)5*&%<;&% #)%'7'("'%<&+)836#")5%6#%&(&46#&<%#&3>&86#;8&*

0)3B"56#)8"6(%*#;<7%65<%3)<&("5=%)+%)>#"'6(%>8)>&8#"&*% )+%=)(<%6(()7*

e"B86#")56(%*>&'#8)*')>7%)+%565)*#8;'#;8&<%*;8+6'&%*7*#&3* K"3&C8&*)(4&<%'6#$)<)(;3"5&*'&5'&%bK_0gc

160L,%:%K$&%D56(7#"'6(%JF;">3&5#%M6#6B6*&

Susan Meuwly

Empa

NMMC

Annual Activity Report 2010

CCMX Team

Management %&'()$*+&,-$./&01,-,& 0$6"8 I68&5?*'8"4&5&8 &>+(?'$ 2&)$3+45+60,$7'-8,-$ 1656="5=%M"8&'#)8 56#$6("&?G)5=&5 &>+(?'$ *+456,,-$"'660-9 D<3"5"*#86#)8 I6#$(&&5?')(("5* &>+(?'$ !+&0+$2,6+6':, D<3"5"*#86#)8 368"6?<&(6()7& &>+(?'$ .;,$30,<0+&'<9=0 D<3"5"*#86#)8 *;&?5"&E"68)E*I" &>+(?'$

SPERU Surface, Coatings and Particles Engineering %&'()$#,0-&0/5$#'(>+--$ JA^g%:%M"8&'#)8 $&"58"'$?$)+3655 &>+(?'$ 2&)$3+45+60,$7'-8,-$ T'"&5#"+"'%65<%Q5<;*#8"6(%g"6"*)5%@++"'&8 56#$6("&?G)5=&5 &>+(?'$ 2&)$30=6+;9$?@56,&$ T'"&5#"+"'%65<%Q5<;*#8"6(%g"6"*)5%@++"'&8 5"I(6;*?B;&$(&8 &>+(?'$

MatLife Materials for the Life Sciences 2&)$*+45+&0-+$!+-0;&+ J3>6%:%M"8&'#)8 I6#$68"56?365";86 &3>6?'$ A--,B*+45&0-$?'&T'"&5#"+"'%65<%Q5<;*#8"6(%g"6"*)5%@++"'&8 655&CI6#$8"5?B)85 &3>6?'$ 2&)$C+64,&$./50660-8$ T'"&5#"+"'%65<%Q5<;*#8"6(%g"6"*)5%@++"'&8 E6(#&8?*'$"(("5= B(;&E"5?'$

Annual Activity Report 2010

MERU Metallurgy %&'()$!0/5,6$D+EE+F JA^g%:%M"8&'#)8 3"'$&(?86>>6l &>+(?'$ .;9+-$!,;<6: T'"&5#"+"'%65<%Q5<;*#8"6(%g"6"*)5%@++"'&8 *;*65?3&;E(7 &>+(?'$

NMMC Nano- and Microscale Materials Characterisation for Industry and Academia %&'()$#+-9$7'9,($#;8$ J3>6%:%M"8&'#)8 $65*CG)*&+?$;= &3>6?'$ "50+&+$"'&40/,660$ T'"&5#"+"'%65<%Q5<;*#8"6(%g"6"*)5%@++"'&8 '$"686?')8#"'&((" &3>6?'$ .;9+-$!,;<6: T'"&5#"+"'%0))8<"56#)8 *;*65?3&;E(7 &>+(?'$

CCMX Steering Committee A8)+?%V68&5%T'8"4&5&8%bJA^gc%C%0$6"8 M8?%m6'F;&*%]6;8%b_)(&Pc M8?%D(&P%M)33655%b0TJ1c A8)+?%A$"(">>&%d"((&#%bJA^gc% M8?%A"&865=&()%d8{5"5=%bJ3>6c M8?%L65*C!6(#&8%T'$(`>+&8%bT;(l&8c A8)+?%_)(65<%T"&=E68#%bJKL%[;8"'$c A8)+?%_6(>$%T>)(&56I%bJKL%[;8"'$c A8)+?%m?%^8"*)%465%<&8%e&&5%bATQc

CCMX International Advisory Board A8)+?%J<;68<%D8l#%bT668(65<%\5"4&8*"#7c A8)+?%M64"<%d86"5=&8%b\5"4&8*"#7%)+%\#6$c A8)+?%A$"(">>&%168';*%bJ')(&%Z6#")56(&%T;>h8"&;8&%<&%0$"3"&c

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www.ccmx.ch Texts :

Elsbeth Heinzelmann, Bern and CCMX

Photos :

CCMX, EPFL, ETH Zurich, Empa, PSI, CSEM Layout & Design :

www.antidote-design.ch Printing :

i comme imprimeurs sa (www.icomme.ch) © CCMX – April 2011 Cover Image: Hossein Meidani, Computational Materials Laboratory (LSMX), EPFL. A pore grown between spherical solid grains arranged in a cubic network.

-0.1

0.05

Mean Curvature

0.2