FLT3 antibody Antibodies for hematologic malignancies

Antibodies for Hematologic Malignancies Research Increase Your Efficiency and Value with Consistent Performance Antibodies: detection, imaging, diagnostic, etc. info@creative-biolabs.com www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research High-quality, validated antibodies for all your needs Creative Biolabs offers high quality ready-to-use catalogue antibodies, as well as flexible and comprehensive customized services for the antibody production to facilitate the basic discovery of hematologic malignancies. Empowered by extensive experience and senior teams, we are

committed to offering cutting-edge antibodies with superior performance for a wide range of applications to best maximize the success of your projects at the forefront of technological innovation.

Trusted Antibody Quality

01

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research Hematologic Malignancies Hematologic malignancies, also known as cancer of the blood or lymph system, are classified as three main types including leukemia, lymphoma and myeloma. To facilitate hematologic malignancies research, Creative Biolabs offers a wide array of antibodies to help meet your needs and budget requirements, increasing efficiency and offering the best value for a wide range of applications and specific assays.

A Quick Glance at Key Targets in Hematologic Malignancies Kind reminder: If you are interested in any other targets, please visit our website or contact us.

Type

Sub-type Acute Myeloid Leukemia

Antibody targets

Key signaling pathway Transcription factors

• • •

Splicing factor

•

FLT3, NRAS, C-KIT, PTEN NPM1, CEBPA, RUNX1, WT1, TP53 DNMT3A, IDH1/IDH2, TET2, ASXL1, EZH2, MLLPTD EVI-1, MN1, BAALC, ERG, miR-181 CD5, CD19, CD20, CD23, CD79b, TP53 CXCR4, CXCL12, CD40, CD40L, IL4R, IL4, VLA4, VCAM1 SF3B1

DNA damage response genes

•

TP53, ATM

Other frequent mutations Altered histone/chromatinmodifications Immune escape Deregulated BCL6 activity Other Proliferation/Apoptosis Signaling Other

•

BTK, PLCG2, CDKN2A/B, NOTCH1, MYC

•

CREBBP, EP300, MLL2, MLL3

• • • • • •

B2M, CD58 BCL6, MEF2B FOXO1, TP53 BCL2, MYC, miR-17~92 TNFRSF14, GNA13, SGK1, PTEN EZH2, BCL6 BSE1, 2p16.1

Constitutive NF-κB/BCR activity

•

TNFAIP3, MYD88, CD79A/B, CARD11

Terminal differentiation block

•

PRDM1, BLIMP1

Apoptosis Cell cycle checkpoint Other JAK/STAT activation Constitutive NF-κB activity Immune escape Deregulated BCL6 activity

• • • • • • • •

BCL2 CDKN2A/B SPIB JAK2, JMJD2C, SOCS1, STAT6 TNFAIP3 PDL1, PDL2, CIITA BCL6 KRAS, NRAS, DIS3, BRAF, FAM46C, TRAF3, TP53, ACTG1, HIST1H1E, EGR1, ATM, MAX, FGR3, CCND1, IRF4 CRBN, IKZF1/3, CUL4, MAPK,NF-kB, MYC, WHSC1/FGFR3, MAF, CCND3, MAFB

Epigenetic modifiers Overexpressed Clinical markers

Leukemia Chronic Lymphocyti c Leukemia

GCB-&ABCDLBCL

GCB-DLBCL Lymphoma ABC-DLBCL

PMBCL

Myeloma

Function

Multiple Myeloma

Microenvironment

Recurrently mutated targets Other mutated targets

02

• • •

info@creative-biolabs.com

•

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research Popular antibodies for Acute Myeloid Leukemia Acute myeloid leukemia (AML) is a heterogeneous malignant disorder of hematopoietic stem/progenitor cells, characterized by the rapid clonal expansion of abnormal blasts of myeloid lineage (white blood cells). The root cause can be classified by chromosomal abnormalities, recurrently mutated genes, and epigenetic modifications. Creative Biolabs offers a variety of antibodies on a full spectrum of AML for your research.

Antibodies for AML key signaling targets Targets FLT3

NRAS

KIT

PTEN

Clone

Applications

Species reactivity

Cat.No.

7D6 1A11 BV10A4 RBT-NRAS 2G9 CBWJN-0812 5C8D4 3A8 104D2 10BA33

WB E F, IP C, P WB, F, E, IF WB, F, IP WB, E, IH, P E, WB F IF, WB

CBMAB-C8639-LY CBMAB-C3514-LY CBMAB-F0575-CQ CBMAB-N0518-WJ CBMAB-N0517-WJ CBMAB-N3523-WJ CBMAB-C7434-LY CBMAB-K0974-LY CBMAB-K0116-LY CBMAB-1516CQ

D4.3

WB, IP

1B8

E, F, IC, IF, WB

Human Human Human Human Human Mouse, Rat, Human Human Human Cattle, Human, Monkey Human Human, Mouse, Rat, Hamster, Monkey, Dog, Chicken Human, Mouse

CBMAB-P3310-YC CBMAB-P3306-YC

Antibodies for AML key transcription factors Targets

Clone

Applications

Species reactivity

Cat.No.

AT23F1 7H10B9

E, WB, IC, IF, F WB, IH, IF, E

CBMAB-N3150-WJ CBMAB-N3149-WJ

FC82291

WB, IP, E, P, IC, IC

5B7 4E10 16C12B70 A-2 2C10 3H2L6 WT1/857 + 6F-H2 6F-H2 WT1/1434R DO-1 SP5

E, F, IC/IF, IH, P, WB WB, E, F WB, IF WB, IP, IF, P, E WB, E, IF, P WB F, IF, IH, P WB, P, C, IP F, IF, IH F, GS, IF, P, IP, WB P, WB WB, F, E, IC, IF, IP, P, C

Human Human, Monkey Human, Mouse, Rat, Bovine, Canine, Donkey, Hamster, Monkey Human Human Human, Mouse Mouse, Rat, Human Human Human, Mouse Human, Mouse, Rat Human, Mouse, Rat Human Human Human Human, Mouse, Dog, Chicken, Hamster, Monkey

NPM1

CEBPA

RUNX1

WT1

TP53

BP53-12

CBMAB-N3156-WJ CBMAB-C7347-LY CBMAB-C6829-LY CBMAB-C3346-LY CBMAB-R3853-CN CBMAB-1789-CN CBMAB-R3846-CN CBMAB-W0385-WJ CBMAB-W0142-WJ CBMAB-W0383-WJ CBMAB-T3717-YJ CBMAB-T3721-YJ CBMAB-P3724-YC To be continued.

03

Antibodies for Hematologic Malignancies Research Antibodies for AML epigenetic modifiers Targets DNMT3A

IDH1

IDH2

TET2 ASXL1 EZH2

Clone

Applications

Species reactivity

Cat.No.

64B814.1 64B1446 4G5F11 1D1 CBYY-I1657 IDH1/1152 CBYY-I1122 5F11 CBFYM-1136 CBYJT-2576 CBYJT-2578 CBFYM-3155 CBYC-A829 6E2 6G4F4 CBFYE-0268 CBFYE-0131

IC, IH, WB WB, IC, IF, CI, IH E, WB, P, F P, WB WB, IP, IF, F C, WB, F, P, IF, MC WB, IH, IF, P E, P, WB WB, IH, E WB, IP, IF, E WB, IP IP, WB DB E, WB WB, F, E, IH, IC, MC WB, IP, P, IF, F, CI IC, IF, IH, IP, WB

Mouse Human, Mouse Human Human Human, Mouse, Rat, Monkey Human Human, Mouse, Rat Human Human Human Human, Mouse Human, Mouse Human Human Human Human, Mouse, Rat, Monkey Human, Mouse, Rat

CBMAB-D1426-YC CBMAB-D1417-YC CBMAB-D1416-YC CBMAB-I0237-YY CBMAB-I2827-YY CBMAB-I0238-YY CBMAB-I2290-YY CBMAB-I1443-YY CBMAB-M1293-FY CBMAB-T1746-YJ CBMAB-T1748-YJ CBMAB-M3352-FY CBMAB-A3825-YC CBMAB-A3824-YC CBMAB-E0234-FY CBMAB-E0547-FY CBMAB-E0257-FY

Antibodies for AML overexpressed factors Targets MN1

BAALC

ERG

Clone

Applications

Species reactivity

Cat.No.

CBFYM-2434 BM-3 5H13 CBYY-0104 CBYY-0103 CBYY-0102 2C6

WB, IP, IF, E C, E, IP, WB IH, F WB, IP, IF, E WB, IP, IC E, WB IP, WB, M

CBMAB-M2621-FY CBMAB-P0507-YC CBMAB-P0506-YC CBMAB-0104-YY CBMAB-0103-YY CBMAB-0102-YY CBMAB-0353-YC

CBFYE-0255

WB, IP, P, IF, F

CBFYE-1189

WB, IP, IF, P, E

Mouse, Rat, Human Human Human, Mouse Human Human Human Human Human, Mouse, Rat, Hamster, Pig, Guinea pig, Horse Mouse, Rat, Human

CBMAB-E0527-FY CBMAB-E1759-FY

Popular antibodies for Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia (CLL) is a B cell malignancy characterized by the clonal expansion of CD5+ B cells in the peripheral blood, bone marrow, and secondary lymphoid organs. Creative Biolabs offers a variety of antibodies on a full spectrum of CLL for your research.

Antibodies for CLL clinical markers Targets CD5

CD19

Clone

Applications

Species reactivity

Cat.No.

2B8 CRIS1

F, IC/IF, P, WB F, IF, IP, C

CBMAB-C4727-LY CBMAB-C0605-CQ

CD5/54/F6

WB, F, IF, IP, P, C

6D5 1G3 LE-CD19

F, IP, WB E, IP, WB F, E, IH, P

Human Human, Primate Human, Rat, Pig, Cattle, Chicken, Horse, Guinea Pig, Monkey, Rabbit Mouse Human Human

CBMAB-C0538-CQ CBMAB-C8216-LY CBMAB-C4157-LY CBMAB-C4482-CQ To be continued.

04

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research Antibodies for CLL clinical markers Targets

Clone

Applications

Species reactivity

Cat.No.

CD20

2H7

D, CI, IP

Human, Monkey

CBMAB-0947-LY

CD79b

3A2-2E7 4E10-2A10 CB3-1

F, IH, WB E, IP, WB CB3-1 WB, F, E, IC, IF, IP, P, C P, WB F, GS, IF, P, IP, WB

Human Human Human Human, Mouse, Dog, Chicken, Hamster, Monkey Human Human

CBMAB-C0185-YY CBMAB-C6834-LY CBMAB-C0526-CQ

BP53-12

TP53

SP5 DO-1

CBMAB-P3724-YC CBMAB-T3721-YJ CBMAB-T3717-YJ

Antibodies for CLL targets in microenvironment Targets CXCR4

CXCL12

CD40

IL4R

IL4

VCAM1

Clone

Applications

Species reactivity

Cat.No.

30L4 2B11

F, IH, P, B/N, MC F, C, WB

CBMAB-C0941-LY CBMAB-C0822-LY

12G5

P, C, F, IF

14L308 9N26 1H15L3 1C10 2H8 C40/1605 25465.45 7E10C7 16F23 4D9

F, IH C, F E F, C, IP E WB, F, IF, P E, FN, WB, F, P E WB IF, N, WB

8D4-8

E, F, IH, IP, FN, IS, N

11B11 M/K-2 6G9 1.4C3

F, E FN, IF, C, IP E, P, WB F, P, IF

Mouse Mouse Human, Chimpanzee (P), Monkey (P), Baboon (P) Human Human Human Mouse Human Human Human Human Mouse Human Human, Chimpanzee, Cynomolgus monkey, Rhesus monkey, Baboon Mouse Mouse Rabbit, Human Human

CBMAB-1504-CN CBMAB-C3163-LY CBMAB-C9332-LY CBMAB-C4227-LY CBMAB-C0485-LY CBMAB-C5302-LY CBMAB-C0483-CQ CBMAB-C1377-LY CBMAB-C8655-LY CBMAB-C3371-LY CBMAB-I1327-YY CBMAB-I1755-YY CBMAB-P0397-YC CBMAB-0946CQ CBMAB-0950CQ CBMAB-0953CQ

Antibodies for CLL splicing factor Targets SF3B1

Clone

Applications

Species reactivity

Cat.No.

CBXS-2265 CBXS-1299

WB, IP, IF, E WB, P, IF

CBMAB-S5027-CQ CBMAB-S4158-CQ

CBXS-5436

WB

Mouse, Rat, Human Mouse, Rat, Human Human, Mouse, Rat, Monkey, Hamster, Cattle

CBMAB-S2647-CQ To be continued.

05

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research

Antibodies for CLL DNA damage response genes Targets TP53

ATM

Clone

Applications

BP53-12

WB, F, E, IC, IF, IP, P, C

SP5 DO-1

P, WB F, GS, IF, P, IP, WB

5C2

IC, IF, IH, WB

2C1 1B10

WB, F, E, IH, IC, IF, P E, IP, WB

Species reactivity Human, Mouse, Dog, Chicken, Hamster, Monkey Human Human Human, Mouse, Non-Human primate, Rat Human, Mouse, Rat, Monkey Human, Mouse, Rat

Cat.No. CBMAB-P3724-YC CBMAB-T3721-YJ CBMAB-T3717-YJ CBMAB-A3974-YC CBMAB-A3970-YC CBMAB-A3969-YC

Antibodies for CLL frequently mutated targets Targets BTK PLCG2 CDKN2A CDKN2B

NOTCH1

MYC

Clone

Applications

Species reactivity

Cat.No.

EP420Y 9F2 CBYC-A921 3A8B6 2D9E8 1E10C11 1D7D2 1E12E10 4C6/4 DCS-114 8H4 2D11 8G10 3E12 4G1 PL14 4H3 33A12E10

WB, IP E, M WB, IC, P, C, E E, WB, P, IF, IC, F E, WB, IF, IC, F WB, F, E, IH E, WB, P, IF/C, F WB, P WB, E, IC, IF IC, IF, IP IF, P, WB F, P, WB E, IC, F, WB IF, IH, WB E, WB WB, IF, IP IC, IP, WB WB, P, F, E, IC/IF

Human, Mouse (P), Rat (P) Human Rat Human Human Human Human Human, Mouse, Rat Human Human Human Human Mouse, Rat Human Human, Mouse Human, Monkey Human, Zebrafish Human

CBMAB-1230-CN CBMAB-0420-CN CBMAB-A4264-YC CBMAB-P2066-YC CBMAB-P2064-YC CBMAB-P2063-YC CBMAB-C3868-LY CBMAB-C3919-LY CBMAB-P0203-YC CBMAB-P0207-YC CBMAB-C9231-LY CBMAB-C4859-LY CBMAB-1430-YC CBMAB-N3011-WJ CBMAB-N3013-WJ CBMAB-C3833-CQ CBMAB-C7044-LY CBMAB-C5534-LY

Popular Antibodies for Diffuse Large B Cell Lymphoma Diffuse large B cell lymphoma (DLBCL) is the most prevalent non-Hodgkin lymphomas (NHLs) in adulthood, comprising 30%–40% of all new diagnoses. Creative Biolabs offers a variety of antibodies on a full spectrum of DLBCL for your research.

Antibodies for GCB- & ABC-DLBCL Targets CREBBP

EP300

Clone

Applications

Species reactivity

Cat.No.

2H5 2B6

IF,WB WB,E

CBMAB-C3128-CQ CBMAB-C4711-LY

RW105

WB,CI,IC/IF,IP,EM,F

F-4

WB,IP,IF,P,E

NM11

WB, IP, P, F, IC/IF

RW109

WB, CI, IP, IC/IF, IP

Mouse,Human Human Human,Mouse,Rat,Mustelid,Prim ate Mouse,Rat,Human Mouse, Rat, Human, Pig, Mink, Monkey Human, Mouse, Rat, Mustelid, Primate

CBMAB-K0005-LY CBMAB-P0308-YC CBMAB-K0423-LY CBMAB-K0424-LY To be continued.

06

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for GCB- & ABC-DLBCL Targets MLL2 MLL3 B2M

CD58

Clone

Applications

Species reactivity

Cat.No.

2E 1 9H13L17 4C10 CBFYM-1193 CBYY-0044 CBYY-2058 CBYY-0045 2D11-B10 TS2/9

E, P, WB F, IC, IF WB, F WB, E E, WB, IH, IP, F, R E, IF, P, RNAi, WB E, WB, IH, F E, IF, P, WB F WB, IP, E, C, N, F, B, IC, IF

Human Human Human Human Human Human Human, Pig Human Human

CBMAB-K1432-LY CBMAB-K1433-LY CBMAB-K1429-LY CBMAB-M1350-FY CBMAB-0044-YY CBMAB-2407-YY CBMAB-0045-YY CBMAB-C4867-LY CBMAB-C2080-CQ

Mouse, Human

CBMAB-L0217-YJ

CBYJL-146

BCL6

MEF2B FOXO1

TP53

Antibodies for Hematologic Malignancies Research

CBYY-0435

F, P, WB

CBYY-0446 1D3 2F9 2A11 CBFYM-2028 7H3 C29H4 CBXF-3732 DO-7

WB, IP, IF, E IP, WB, M IP, WB, M IP, WB, M WB, IP, IF, E IC, IF, P, WB WB, IP, P, IF, F E, IF, IH, P, WB WB, F, E, IC, IF, P, C

BP53-12

WB, F, E, IC, IF, IP, P, C

CBYJT-4251

C, F, IC, IF, IP, P, WB

Bovine, Human, Mouse, Ovine, Pig, Rabbit, Rat Human, Mouse Human Human Human Mouse Human Human, Mouse, Rat, Monkey Human, Mouse Human, Cattle, Primate Human, Mouse, Dog, Chicken, Hamster, Monkey Human, Cattle, Monkey

CBMAB-0437-YY CBMAB-0449-YY CBMAB-0161-YC CBMAB-0660-YC CBMAB-0659-YC CBMAB-M2207-FY CBMAB-F1952-CQ CBMAB-F0572-CQ CBMAB-F1764-CQ CBMAB-P3726-YC CBMAB-P3724-YC

CBMAB-T3726-YJ

Antibodies for GCB-DLBCL Targets BCL2

MYC

Clone

Applications

Species reactivity

Cat.No.

CBYY-1676 CBYY-1824 CBYY-1837 9E 10

E, F, IF, P, IP, WB, C E, F, IF, IH, IP, WB WB. IP, F, C, P, IC E, IF, IH, IP, WB WB, CI, E, F, IH, C, P, IP WB, CI, F, E, IH, IP, P, C, MC F, IC, IF, IP F, IC, IF, IP F WB E, WB E, WB E, IF, WB IF, SE, E, WB, P F, IH, IP, WB

Human Mouse, Human Mouse, Rat Fish, Zebrafish

CBMAB-2025-YY CBMAB-2173-YY CBMAB-2186-YY CBMAB-0325-CN

Human, Mouse, Chicken, Yeast

CBMAB-M3082-FY

Human, Mouse, Chicken, Yeast

CBMAB-C9324-LY

Human Human Mouse Mouse, Rat, Human Human Human Human Human Human, Mouse, Rat

CBMAB-T3128-YJ CBMAB-T3117-YJ CBMAB-H0183-FY CBMAB-G4057-LY CBMAB-G4055-LY CBMAB-G4053-LY CBMAB-S2857-CQ CBMAB-S3302-CQ CBMAB-S6248-CQ

CBFYM-2888 9E 11

TNFRSF14 GNA13 SGK1

Laury-1 CBYJT-3737 CBFYH-3312 6F6-B5 5E 90 10C404 4D7-G3 CBXS-0331 CBXS-3519

To be continued.

07

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for GCB-DLBCL Targets PTEN EZH2 BCL6

Antibodies for Hematologic Malignancies Research

Clone

Applications

Species reactivity

Cat.No.

A2B1 1B8 13B653 CBFYE-0268 CBFYE-0131 6G4F4 CBYY-0446 CBYY-0443 CBYY-0442

IS E, F, IC, IF, WB E, F, IC, IF, WB WB, IP, P, IF, F, CI IC, IF, IH, IP, WB WB, F, E, IH, IC, MC WB, IP, IF, E IP, WB, IC, P WB, IP, IF, P

Human, Dog, Mouse, Rat Human, Mouse Human, Mouse Human, Mouse, Rat, Monkey Human, Mouse, Rat Human Human, Mouse Human Human, Mouse

CBMAB-P3309-YC CBMAB-P3306-YC CBMAB-P3304-YC CBMAB-E0547-FY CBMAB-E0257-FY CBMAB-E0234-FY CBMAB-0449-YY CBMAB-0446-YY CBMAB-0445-YY

Clone

Applications

Species reactivity

Cat.No.

8E8.38 59A426 4H16 CBFYM-2905 CBFYM-2902 CBFYM-0164 SP18

WB, IP WB, F, IC, IF, P F, IF, IH, IP, WB WB, IC, P, C, E F, IH, P, C F, IC, IF, WB P WB, F, E, IF, IP, P, C, MC

Human Human, Mouse, Rat Human, Mouse, Rat Rat Human, Dog Human, Mouse Human Human, Mouse, Rat, Pig, Cattle, Monkey Human, Mouse, Rat, Pig, Cattle, Primate Human Human Human, Mouse Mouse, Rat, Human Human Human Human, Mouse, Rat Human, Mouse, Rat, Monkey Human, Mouse Mouse Human, Mouse Human, Mouse Mouse Human, Mouse Human Human Human, Mouse, Rat Human, Mouse, Rat Human Human, Mouse, Rat Human Human Human

CBMAB-A4865-YC CBMAB-A4863-YC CBMAB-A4862-YC CBMAB-M3100-FY CBMAB-M3096-FY CBMAB-M0187-FY CBMAB-C4347-CQ

Antibodies for ABC-DLBCL Targets TNFAIP3 MYD88

CD79A

CD79B GNA13 CARD11 PRDM1 BLIMP1 BCL2 CDKN2A CDKN2B

HM47/A9 SPM550

WB, F, IF, IP, P, C

B29/123 3A2-2E7 CBYY-C0140 6F6-B5 10C404 5E 90 CBFYC-0811 1D12 3H2-E8 6D3 5E 7 3H2-E8 6D3 5E 7 Bcl-2-100 CBYY-1897 CBYY-0357 1E12E10 4C6/4 CBXC-2505 2D11 3B6 8C4

WB, IH F, IH, WB E, F, IP, WB WB E, WB E, WB WB WB WB, P, IC, IC, IF IH, WB E, WB, P, IF, IC, F WB, P, IC, IC, IF IH, WB E, WB, P, IF, IC, F P, C, IC, WB E, P, WB, IF, IF E, WB, IH, IF WB, P WB, E, IC, IF E, WB, IH F, P, WB F, P, WB E, WB

CBMAB-C0713-CQ CBMAB-C1109-CQ CBMAB-C0416-CQ CBMAB-C0185-YY CBMAB-C0483-YY CBMAB-G4057-LY CBMAB-G4053-LY CBMAB-G4055-LY CBMAB-C0866-FY CBMAB-C3809-LY CBMAB-P2691-YC CBMAB-P2693-YC CBMAB-P2692-YC CBMAB-P2691-YC CBMAB-P2693-YC CBMAB-P2692-YC CBMAB-A4256-YC CBMAB-2246-YY CBMAB-0358-YY CBMAB-C3919-LY CBMAB-P0203-YC CBMAB-C5043-CQ CBMAB-C4859-LY CBMAB-C5738-LY CBMAB-C9079-LY To be continued.

08

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research

Antibodies for ABC-DLBCL Targets

Clone

Applications

Species reactivity

Cat.No.

SPIB

CBXS-2464 CBXS-5088 CBXS-5699

E, F, IC, IH, WB F, IC, IF, IH, WB WB, IP, IF, F, E

Human, Mouse Human, Mouse Mouse, Human

CBMAB-S5221-CQ CBMAB-S2308-CQ CBMAB-S0567-CQ

Clone

Applications

Species reactivity

Cat.No.

8E10.2 18H11L8 3F10 4B1 D-4 8A1 CBXS-3257 CBXS-2408 CBXS-5556 CBXS-4271 CBXS-2122 CBXS-2164 59A426 8E8.38 4H16 RBT-PDL1 3F4 CBXC-2555 7-1H CBYY-0446 CBYY-0443

IH, WB IC, IF, WB P F, IF, P WB, IP, IF, E P, WB E, IP, WB IP, WB IP, WB CI, F, IC, IF, P, WB WB, IP, IF, P, E WB, IP, IF, E WB, F, IC, IF, P WB, IP F, IF, IH, IP, WB C, P E, WB IR, E, F, IF, IH, WB WB, IC WB, IP, IF, E IP, WB, IC, P

CBMAB-0278-WJ CBMAB-0071-WJ CBMAB-0183-WJ CBMAB-K0692-LY CBMAB-0318-WJ CBMAB-K0694-LY CBMAB-S5998-CQ CBMAB-S5165-CQ CBMAB-S2763-CQ CBMAB-S1520-CQ CBMAB-S4886-CQ CBMAB-S4927-CQ CBMAB-A4863-YC CBMAB-A4865-YC CBMAB-A4862-YC CBMAB-C5820-CQ CBMAB-C6040-LY CBMAB-C5829-CQ CBMAB-C8422-LY CBMAB-0449-YY CBMAB-0446-YY

CBYY-0435

F, P, WB

Human, Mouse, Rat Human Human, Mouse, Rat Human Mouse, Rat, Human Human Mouse Mouse Mouse Human, Mouse Mouse, Rat, Human Mouse, Rat, Human Human, Mouse, Rat Human Human, Mouse, Rat Human Human Human, Mouse, Pig Mouse, Human Human, Mouse Human Bovine, Human, Mouse, Ovine, Pig, Rabbit, Rat

Antibodies for PMBCL Targets JAK2 JMJD2C SOCS1 STAT6

TNFAIP3 PDL1 CIITA BCL6

CBMAB-0437-YY

Popular Antibodies for Multiple Myeloma Multiple myeloma (MM) is a hematological malignancy characterized by abnormal accumulation of clonal plasma cells (PCs) in the bone marrow (BM). MM accounts for 10% of hematological malignancies and 1.6% of all U.S. cancer deaths. Creative Biolabs offers a variety of antibodies on a full spectrum of MM for your research.

Antibodies for MM recurrently mutated targets Targets KRAS NRAS DIS3

Clone

Applications

Species reactivity

Cat.No.

2F8 AT2F8 F132-62 AT2G9 2G9 CBWJN-0812 2C7 6C7B2 14i132

WB E, F, IC/IF, WB IC, IF, C, P, IP E, WB, IH WB, F, E, IF WB, F, IP E, IF, WB WB, P, F E, F, IH, WB

Human Human Human, Mouse, Rat Human Human Mouse, Rat, Human Human Human Human

CBMAB-K1498-LY CBMAB-K1516-LY CBMAB-K1518-LY CBMAB-N3522-WJ CBMAB-N0517-WJ CBMAB-N3523-WJ CBMAB-D0939-YC CBMAB-D0940-YC CBMAB-D0941-YC To be continued.

09

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research Antibodies for MM recurrently mutated targets Targets BRAF

TRAF3

TP53

ACTG1

HIST1H1E

EGR1

ATM

MAX

CCND1

IRF4

Clone

Applications

Species reactivity

Cat.No.

CBYY-2108 CBYY-2024 EP152Y CBYJT-4509

IHC, P, WB IC, IHC, P, WB WB, P, FC, IP PL, CE, E, WB

CBMAB-2457-YY CBMAB-2373-YY CBMAB-1219-CN CBMAB-T4014-YJ

53/c-Raf-1

WB, IF, IP

4A3 1285C CBWJW-083 1F7

E, IC, IF, P, WB WB, IHC, IF, IPS, FC WB, IPS, PE IP, M, WB

2G2

IF, C, P, WB

2A3

WB

5C5

IH, C, P

CBFYH-1156

WB, CI

CBFYH-1155 CBFYH-1157 T.160.5 44D5 CBFYE-0605 9A2 1B10

E, WB E, IC, WB CI, IC, IF, P, IP, WB WB, IP, IF, F, CI F, IC, IF, IP, WB E, IP, WB E, IP, WB

5C2

IC, IF, IH, WB

CBFYM-1775 1E 7 CBFYM-1774 CCND1/809 DCS-6 17H3L3 2F2 SP114 CBYY-I1715

E, F, IC, IF, IP IP, M WB, E WB, F, P, IF P, C, IC, WB F, IC, IF, WB WB, E, IH P, WB WB, IP, IF, E

Human, Monkey Human, Dog, Monkey, Rat Mouse, Rat, Human Human Human, Chicken, Dog, Mouse, Rat Human Human, Mouse Human, Mouse, Rat Human Chicken, Cattle, Human, Rabbit, Xenopus laevis Mouse, Rat, Rabbit, Chicken, Human, Pig, Zebrafish Human, Pig, Rat, Carp, Guinea pig, Rabbit, Sheep, Snake, Xenopus, Cattle Human, Monkey, Hamster, Cattle, Dog Human Cattle, Human Cattle, Human, Mouse, Rat Human, Mouse, Rat, Cattle Human, Mouse, Rat Human Human, Mouse, Rat Human, Mouse, Non-Human primate, Rat Human Human Human Human Human, Mouse, Rat Human Human Human mouse, rat, Human

CBMAB-C3198-LY CBMAB-A4894-YC CBMAB-1838CQ CBMAB-T0002-WJ CBMAB-0266-LY CBMAB-A0915-YC

CBMAB-G0002-LY CBMAB-A0918-YC CBMAB-H2110-FY CBMAB-H2109-FY CBMAB-H2111-FY CBMAB-E0996-FY CBMAB-E1004-FY CBMAB-E0997-FY CBMAB-A3976-YC CBMAB-A3969-YC CBMAB-A3974-YC CBMAB-M1943-FY CBMAB-0636-YC CBMAB-M1942-FY CBMAB-C0529-CQ CBMAB-G1315-LY CBMAB-C3434-LY CBMAB-I0694-YY CBMAB-I1084-YY CBMAB-I2885-YY To be continued.

10

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research Antibodies for MM other mutated targets Targets CRBN

IKZF1

IKZF3

CUL4

MAPK

MYC

WHSC1

FGFR3

MAF

CCND3

MAFB

11

Clone

Applications

Species reactivity

Cat.No.

2A9D11 3B12F7 CBYY-C2841 CBYY-I1646 SP108 CBYY-I0118 3H5-G7 8B2 CBYY-I0592

E, C, WB C, WB IH, WB WB, IF, F, CI WB, IH, P, F WB, IF, IP, IS WB, IP, IF, E WB, F, IP WB, IH, E

CBMAB-C4642-LY CBMAB-C5699-LY CBMAB-C4282-YY CBMAB-I2816-YY CBMAB-I1083-YY CBMAB-I0343-YY CBMAB-A4476-YC CBMAB-A4477-YC CBMAB-I1295-YY

1A7F12

E, IF, IH, IP, WB

CBFYC-2475 CBXC-1934

E, IF, IH, IP, WB WB, IH, P

Human, Mouse, Pig Human Human Human Human Mouse Human Mouse Human Human, Monkey, Mouse, Pig, Rat Human, Mouse, Pig, Rat Human, Mouse, Dog

4C11

E, IC, IF, IH, C, P, WB

Human, Mouse, Monkey

CBMAB-1201-YC

ERK-7D8

E, EMSA, IC, IF, P, IP, WB

MAPK-YT

E, IC, IF, P, IP, WB

9E10 MYC275 4H3 2A11 CBWJW-219 CL1063 6G11 2H10B4 CBXF-1158 CBFYM-1284 CBFYM-1282 CBFYM-1276 CBFYC-1042 CBXC-0145 CBXC-0146 CBFYM-1282 CBFYM-1280 CBFYM-1281

E, IF, IH, IP, WB F, IH, IF, P IC, IP, WB IP, M WB, IH, P IH, P, WB N, WB E, WB, P, F WB, IP, IF WB, IP, IF, E WB, IP, IF, E WB, IP, IF, P, E F, IF, IH, IP, N, WB F, IF, IH, IP, N, WB F, IF, IH, IP, N, WB WB, IP, IF, E WB, IH, F WB, IC

Mouse, Rat, Dog, Human, Zebrafish Mouse, Rat, Cow, Human, S. cerevisiae, Common fruit fly Fish, Zebrafish Human Human, Zebrafish Human Human Human, Mouse Human Human Human, Mouse Mouse, Rat, Human Mouse, Rat, Human Mouse, Rat, Human Human, Mouse, Rat Human Human Mouse, Rat, Human Human Human, Rat

info@creative-biolabs.com

CBMAB-C3585-LY CBMAB-C2548-FY CBMAB-C5361-CQ

CBMAB-1736-YC CBMAB-1735-YC CBMAB-0325-CN CBMAB-C0947-CQ CBMAB-C7044-LY CBMAB-0304-LY CBMAB-N0003-WJ CBMAB-1717-YC CBMAB-F1776-CQ CBMAB-F1323-CQ CBMAB-F0875-CQ CBMAB-M1443-FY CBMAB-M1441-FY CBMAB-M1435-FY CBMAB-C1099-FY CBMAB-C4838-CQ CBMAB-C4839-CQ CBMAB-M1441-FY CBMAB-M1439-FY CBMAB-M1440-FY

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research “ Creative Biolabs owns comprehensive antibody products and related services. Please contact us for more detailed information and our team will get back to you as soon as possible. We are always here to serve you to help promote your projects. The list above only exhibits a small part of our products. Please visit our website for more information. https://www.antibody-creativebiolabs.com

�

Antibody Services Guidance What's my target?

Popular

Specific

Catalogue Ab Available or not in Creative Biolabs?

Custom Ab

No

Specific epitope

Yes

Order the Catalogue Ab Online

Mouse or rabbit?

Batch to batch reproducibility Monoclonal Ab

Test the Ab

Polyclonal Ab

Epitope synthesises or not?

Suit my project

12

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research Highlight Features: Innovative technologies and ideas Numerous worldwide customers High-level Ph.D. scientists and experienced technicians High efficiency and short turnaround time Close collaboration Extensive forefront knowledge sharing Advanced and one-stop platforms

“

With extensive experience and over a decade superior antibody services for numerous worldwide customers, Creative Biolabs has blossomed into a service leader in the field of antibody products and services. We offer a comprehensive set of package services and also individual modules, and aim to maximize the success of your breast cancer research discovery and development.

�

Custom Antibody Service Process

Submit protein sequence

Antigen design

Antigen synthesis

Antibody production and purification

Quality control

Delivery

A wide range of applications WB

IHC

ELISA

IP/ChIP

IF/FC

Functional assay

13

info@creative-biolabs.com

www.antibody-creativebiolabs.com

Antibodies for Hematologic Malignancies Research Leverage the expertise of our senior scientists to obtain a wide array of antibodies or custom products to fit your project.

Tel: 1-631-381-2994

Fax: 1-631-207-8356 Email: info@creative-biolabs.com www.antibody-creativebiolabs.com 45-1 Ramsey Road, Shirley, NY 11967, USA

The trusted antibody and custom service & solution provider.

Our promise: Guaranteed product quality, expert customer support.

10