CANFAR Annual Report 2009

Annual Report 2008/2009

national charitable foundation that raises awareness to generate funds for research into all aspects of HIV infection and AIDS.

CANFAR Annual Report 2008/2009

Who we are

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The Canadian Foundation for AIDS Research (CANFAR) is the only

Now, more than ever 1

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Now, More Than Ever Recent progress in the treatment and prevention of HIV/AIDS has offered much encouragement. Notably, intensive efforts to prevent mother-to-child transmission of the disease have seen measurable results in only a few short years. However, the progress achieved serves also to highlight the burden of the disease that remains.

Sadly, while HIV/AIDS claimed an estimated 23,000 lives in North America in 2007, it is the world’s poorest and most vulnerable who continue to suffer disproportionately. In sub-Saharan Africa, an estimated 22 million people are infected. Women in this region account for over 60% of adults living with HIV, and they continue to face greater infection risks than men. Among 15 to 24 year-olds in South Africa, women account for 90% of new HIV infections.

Worldwide, an estimated 2.5 million children are HIV-positive.

Annually, over 300,000 children die from the disease.

As a person living with HIV, there are so many reasons to me why research is so “

important. We need to understand the psychological issues, the side-effects of drugs,

the progression of the virus in our bodies and sexual behaviours to prevent further infections. If I were to win the Lotto 6/49, I’d honestly turn in my winnings if it meant finding a cure. – Greg Downer, HIV-Positive

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• In Canada, the proportion of women infected has risen by 6% since 2002.

• 50% of Canadian Grade 9 students wrongly believe there is a vaccine to prevent HIV/AIDS. • Almost 73,000 Canadians are HIV positive, and 27% don’t know it yet.

Prevention and treatment are important. Meanwhile, the need for a vaccine is critical. Help us end AIDS through research.

Now, more than ever.

• The number of new HIV infections continues to outstrip the advances made in treatment numbers—for every two people put on antiretroviral drugs, another five become newly infected.

• An estimated 33 million people were living with HIV in 2007.

There were 2.7 million new HIV infections and 2 million AIDS-related deaths last year.

• Globally, women account for half of all HIV infections.

• HIV prevalence among pregnant women attending antenatal clinics in Sub-Saharan Africa is as high as 40%.

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The percentage of pregnant women living with HIV who received antiretroviral treatment to prevent mother-to-child transmission increased from 9% in 2004 to 33% in 2007, but the majority remained untreated.

CANFAR Annual Report 2008/2009

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CANFAR grants support leading-edge research and breakthroughs in the study of HIV/AIDS. Canadian research is at the forefront of new discoveries in combatting the disease.

Dr. Sadhna Joshi at the University of Toronto is working to discover ways to combat HIV through gene therapy. In her research, Dr. Joshi targets both the cells that are infected by HIV, and the virus itself. Dr. Joshi is experimenting with ways to prevent infection by removing receptors that HIV uses to enter immune cells. She is also targeting genes in HIV to prevent replication after infection.

Dr. Clifford Lingwood from The Hospital for Sick Children and Dr. Donald Branch from Canadian Blood Services have identified a new resistance factor in the battle against HIV. They discovered that immune cells from individuals who have a certain rare blood type called blood group antigen Pk, also have a drastically reduced sensitivity to HIV infection. This factor protects cells from infection, indicating that it may have therapeutic potential.

this country. You’re not an insular place, you’ve always looked outside yourself, beyond the line of the horizon.

- Bono

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Dr. Frank Plummer from the University of Manitoba is studying a small group of Nairobi prostitutes to discover the source of their natural resistance to HIV infection. He has discovered that HIV resistant women have higher levels of a protein called elafin/trappin-2 that helps to confer immunity. Dr. Plummer was named Canada’s Health Researcher of the Year in 2007 for his work on HIV/AIDS. Dr. Mark Wainberg, CANFAR funded researcher and Director of the McGill University AIDS Centre, discovered a critical component in the highly effective “AIDS cocktail”. This major breakthrough led to a dramatic fall in AIDS deaths and has improved the lives of people living with HIV/AIDS since the mid-1990s. Dr. Wainberg continues to make discoveries at the forefront of HIV/AIDS research with a focus on anti-viral drugs, understanding drug resistance, and gene therapy. For his seminal contributions in the field, Dr. Wainberg has been made an Officer of the Order of Canada and a Chevalier de Legion d’Honneur - the highest honours of Canada and France.

Dr. Deborah Money’s research at the Children’s and Women’s Health Centre of British Columbia has provided new insights to guide the safe use of antiretroviral therapy during pregnancy. Dr. Money studies the risks of toxicity and health outcomes in both mothers and uninfected children following antiretroviral therapy.

< Dr. Sadhna Joshi and Research Group

CANFAR Annual Report 2008/2009

Research highlights

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Research Highlights – “A Canadian Success Story”

Canadian voice is hard wired in my heart. I’m a fan “ The because a certain kind of idealism still seems to be alive in

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Grants Awarded, Cycle 21 (2008-2009)

Grants 2008-09

Research Grants ($80,000): First Year of Two Year Grants 2008/2009

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1 Researcher: Dr. Alan Cochrane Institution: University of Toronto Project: Understanding the Control of HIV-1 Gene Expression 2 Researcher: Dr. Mario Ostrowski Institution: University of Toronto Project: T cell Immunity in HIV/HCV co-infection 3 Researcher: Dr. Naglaa H. Shoukry Co-investigator: Dr. Marina Klein Institution: Centre de Recherche du CHUM Project: Immune Restoration in HIV/HCV co-infected Patients during Interferon Therapy

Research Grants ($80,000): Second Year of Two Year Grants 2008/2009 4 Researcher: Dr. Chen Liang Institution: Lady Davis Institute, Jewish General Hospital Project: Understanding the Anti-HIV-1 Activity of the Insulin-like Growth Factor II mRNA Binding Protein 1 5 Researcher: Dr. Reina Bendayan Institution: University of Toronto Project: Drug-Drug Interactions between Antiretroviral Drugs in intestinal Tissue: Interplay of Transporters and Metabolic Enzymes

11 Researcher: Dr. Sharon Walmsley Co-investigators: Dr. Jeya Nadarajah, Dr. Mona Loutfy Institution: University Health Network Toronto General Hospital Project: Infectious Complications of Bio-Alcamid™ Soft Tissue Endoprosthesis Treatment for HIV-associated Facial Lipoatrophy

6 Researcher: Dr. Helene Cote Institution: University of British Columbia Project: Placental mitochondrial toxicity of HIV therapy during pregnancy 7 Researcher: Dr. Clifford A. Lingwood Co-investigator: Dr. Donald R. Branch Institution: The Hospital for Sick Children Project: Globotriaosyl ceramide as a resistance factor in HIV infection

12 Researcher: Dr. Trent S. Newmeyer Co-investigators: Dr. Mona Loutfy, Dr. Saara Greene Institution: Department of Recreation and Leisure Studies, Faculty of Applied Health Studies, Brock University Project: Role of Socio-Cultural Factors in Pregnancy Planning of Women Living with HIV

8 Researcher: Dr. Johane P. Allard Co-investigators: Dr. Irving E. Salit, Dr. Marek Smieja, Dr. David Ma, Dr. Eva Lonn, Dr. Lehana Thabane Institution: The University Health Network, The Toronto General Hospital Project: Oxidative Stress, Omega-3 fatty Acids and Cardiovascular Disease Risk in HIV-Positive Subjects

Research Grants ($25,000): One Year Grants 2008/2009 9 Researcher: Dr. Jaqueline Sas Institution: Canadian HIV Trials Network Project: CANFAR/CTN Post-Doctoral Fellowship 10 Researcher: Dr. Ariane Alimenti Co-investigators: Dr. John Forbes, Diana Johansen, Dr. Heather McKay, Dr. Melonie Burrows Institution: University of British Columbia, Children’s and Women’s Health Centre of BC Project: Is the Bone Health of HIV Infected Children and Adolescents Compromised?

13 Researcher: Clemon George, Ph.D Co-investigators: Jacqueline Gahagan, Ph.D., Carolyn Byrne, Ph.D., Saara Greene, Ph.D., Robert Weaver, Ph.D., Orville Browne, Ph.D. Josephine Etowa Institution: University of Ontario Institute of Technology Project: Parent Child Communication on Sex and HIV Amongst African-Canadians For complete information regarding grants, visit www.CANFAR.com

CANFAR Annual Report 2008/2009

Dr. Reina Bendayan is a Professor of Pharmaceutical Sciences at the University of Toronto, and a CANFAR grant recipient. She leads a team of researchers focused on the pharmacological treatment of HIV infection of the brain. Untreated HIV viral replication in the brain can cause HIV-encephalitis.

The central nervous system is poorly accessible to many drugs, making treatment a challenge. To overcome this, Dr. Bendayan is encapsulating anti-HIV drugs in nanoparticles that are better absorbed into the brain, resulting in a better HIV fighting effect.

Another challenge in the treatment of HIV is that chronic administration of antiretroviral drugs can increase levels of drug efflux transporters â&#x20AC;&#x201C; proteins that pump anti-HIV drugs back out of infected cells, resulting in drug resistance.

Dr. Bendayanâ&#x20AC;&#x2122;s group has characterized a number of the transporters responsible for this effect, providing important new targets for the successful long-term pharmacological treatment of HIV/AIDS.

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A Tribute to Compassion and Commitment: Dr. Edward S. Kamski

In June 2006, one of Toronto’s pioneers in the treatment of HIV/AIDS patients suddenly passed away. Dr. Edward S. Kamski was a humble hero in his compassion and commitment to the gay community. The medical practice he acquired in 1985 opened its doors to the treatment of HIV/AIDS patients at a time when much fear around the disease prevailed.

Chester Kamski, Edward’s twin brother, recalled that Edward “was quite fearless of HIV/AIDS – fearless of it and fearless in dealing with it.” Edward chose to ignore the warnings in the early days of the AIDS crisis from those who believed infection could occur through casual physical contact like a handshake, or by sharing kitchen utensils.

His longtime secretary and office manager, Ella DiLiberti, recalls that “Dr. Kamski never wore a mask in his life and he refused to wear a cap and gown.” He was sensitive to the feelings of his HIV/AIDS patients who were alienated by the fear and loathing the disease generated. Misunderstood at the time, people with AIDS were often treated as lepers. Edward never saw them that way. “Instead, he treated every patient with compassion, respect, and affection, visiting them in hospital, at home and at Casey House,” said Jim McKinnon, a friend for more than 40 years.

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< Chester Kamski - Brother, Stan Kamski - Brother, and Michelle Schafer - Niece

As a gay man, Edward resolved to make a meaningful difference in the gay community. Every patient mattered deeply to Edward.

“If people needed an hour to talk to him, he gave them an hour.

He never shoved anyone in or out,” said DiLiberti. “That’s one of the things I loved about him.” His sister Joanne remembers how depressed he became toward the end of a shared vacation in Hawaii knowing that when he returned, several of his patients would have passed away.

Edward desperately wanted to find a solution to end AIDS. His quest for more information on the disease led him to attend three or more conferences a year. He was also part of the Primary Care Physicians Group of AIDS doctors who met to collaborate and trade information and support from each other. Edward’s practice was able to treat HIV/AIDS patients, and over the years provided them with the latest AIDS drugs that prolonged and improved their quality of life.

However, what he truly longed for was a vaccine or a cure.

Dr. Kamski realized that the only sustainable answer to the AIDS crisis would be found in research. He honoured that in his will by leaving a very significant bequest to CANFAR. Compassion was trademark to Edward’s name. His patients, his friends, his family and his causes all resonated deeply within him. His generosity saw no end, even in his passing – his legacy gift carries on in the important work of CANFAR. His family was immensely proud to learn of how he wished his assets to be disbursed.

Edward’s devotion to such an important health cause was greatly inspiring - his niece, daughter to his brother Stan, not only became a volunteer for the AIDS Walk Committee and a dedicated fundraiser, but honoured her uncle by choosing Edward as the middle name for her first-born son.

While the circle of life would close one door, it would also open a new one – and with it, a new generation of support and awareness for HIV/AIDS. Edward would be happy in this knowledge.

Although Dr. Edward Kamski was unable to witness a solution to AIDS in his lifetime, CANFAR remains passionately committed on his behalf.

CANFAR Annual Report 2008/2009

Leave a legacy

Edward’s quiet and dedicated treatment of HIV/AIDS patients was colourfully contrasted by his larger-than-life personality and physical presence. His love of parties, song, ornate items, art and opera would seem unlikely of the unassuming demeanour he kept at his medical practice. He even built and lived in a unique, pie-shaped home with 2cm of frontage on Shuter Street that would serve to host many entertaining dinners, and further reinforce his unique sense of humour. His laughter would light up the room, and his smiling, gregarious nature would almost belie the earnest, committed approach he took towards his patients.

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Events 2008-09

CANFAR Events 2008-2009

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Bloor Street Entertains

AIDS Beat

2008 was another great year for our flagship event Bloor Street Entertains.

Eight hundred and fifty guests were dazzled by Toronto’s top chefs, while dining in the exquisite storefronts of the Bloor-Yorkville area. Hosted by Mr. Howard Sokolowski and Linda Frum, the event was a roaring success, drawing praise from publications like Woman.ca who proclaimed the event “the hottest mingling of haute cuisine and haute couture of the season.”

The black-tie event raised approximately $366,000 in support of HIV/AIDS research.

AIDSbeat was a rocking success at the Koolhaus this past year, seeing an intense battle of the bands where competitors battled it out with electric guitars for top honours.

DisOrderly Conduct took home the People’s Choice Award, and The Insecurities won the Lexpert Cup for their performance.

As always, we were honoured to have many distinguished supporters as our dinner guests. In addition to an already spectacular line up, dinner guests included Jason Priestley and Naomi Lowde, Robert Gage, Galen Weston Jr. and Alexandra Schmidt-Weston, Belinda Stronach, Paul Venoit, Shinan Govani, Andy and Valerie Pringle, Rex Harrington, Fefe Dobson, Stefan Brogan, Anwar Mukhayesh, and Ray Perkins. After dinner, The Party at the Royal Ontario Museum had a great draw, with a fabulous crowd of over 1,500 people illuminating the atrium.

For its success and popularity, CANFAR has been honoured with the coveted Canadian Event Industry’s award for Best Fundraising Event, and nominated for the same award twice more. For our efforts this past year, BizBash, Toronto’s Event Planning Magazine, listed us as Toronto’s top benefit event in 2008, for the second year in a row.

Since its inception, Bloor Street Entertains has blossomed into one of the most unique and exciting events in Canada, and has raised an impressive $3.4 million for leading-edge Canadian HIV/AIDS research.

The judging panel included Damon Allen, former Argonaut quarterback; Samantha Tajik, Miss Universe® Canada; and Jim Middlemiss, legal columnist for the National Post.

All in all, over 1,200 professionals were decked out in Rocky Horror Picture Show attire for the bash, which raised an approximate $236,000. With this amount CANFAR brings the overall amount raised in AIDSbeat’s 13 year history over 1.6 million. Those in attendance witnessed a great show – AIDSbeat is a definite highlight on the autumn party circuit.

Spring for Life During the first week of spring, CANFAR raises awareness and support for HIV/AIDS. We do this through our annual flower-selling campaign, Spring for Life. On March 18th and 19th, office towers, shopping malls and subway stations in downtown Toronto hosted the sale of bouquets of gerbera daisies. An impressive $44,000 was raised by the campaign in support of our cause.

The daisy is a universal symbol of faith; faith in the hope that a cure will be found.

As our Executive Director Kerry Whiteside notes, “the flowering of springtime is a symbol of renewal and hope, so flower sales are a perfect way to fundraise for HIV/AIDS research.”

CANFAR Annual Report 2008/2009

Bloor Street Entertains 2008 Have a Heart CANFAR’s 16th annual Have a Heart youth education program pushed the number of students who participated to over 2 million!

From September until the beginning of January, schools registered to take part in the Have a Heart program. The goal of Have a Heart is to change the startling number of Canadian youth who are misinformed about HIV/AIDS. The program also empowers students with reliable information and tools to make safer decisions.

Have a Heart is a peer-to-peer based education program wherein students sell “Heart-o-grams” to one another while increasing awareness of the need for research to fight the HIV/AIDS epidemic.

The program promotes youth volunteerism, leadership and open dialogue around the disease with the goal of decreasing the incidence of new HIV infections among an at-risk demographic.

CANFAR promises participating schools that 100% of the funds they raise through the Have a Heart program will go directly toward funding youth specific HIV/AIDS research. 1500 schools across every province and territory participated in directly spreading awareness to their peers - the most schools ever registered!

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CANFAR Board of Directors Officers Andrew M. Pringle Chair Salah J. Bachir Vice-Chair James K. Stewart President K. Kellie Leitch, M.D., M.B.A., F.R.C.S.(C.) Vice-President Patti A. MacNicol, C.A. Vice-President and Treasurer Patricia Olasker Vice-President and Secretary Board of Directors Casey Antolak Charles A. Armstrong Gordon Capern Shaun Francis Christopher J. Garland The Honourable William Graham Robert Hoppenheim The Honourable Henry N. R. Jackman Stephen Lewis Tristan Michela Glen Murray Ted Nation Stanley Read, M.D., Ph.D., F.R.C.P.(C.) Susan Rimmer

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Gareth Seltzer Penny Shore Leeanne Weld Kostopoulos Ray Williams Advisory Council Richard P. Ellis Co-Chair K. Kellie Leitch Co-Chair H. Michael Burns Past Chair Clive V. Anderson, LL.B. Lauren Andre David Basset David Bensadoun Christopher H. Bunting Barry R. Campbell Jean Coutu Michael B. C. Davies Duncan Dee L. Yves Fortier, C.C., Q.C. Norbert Gilmore, Ph.D., M.D. Paul V. Godfrey Emily Hamilton Stanley H. Hartt Carol Hill Jamey Hubbs David LeGresley

Michael A. Levine, J.D. Leila MacKenzie Maj.-Gen. (Retd.) Lewis W. MacKenzie, CM, OOnt, MSC, CD Dr. Mark MacLoed Teresa Marques Brad Meredith Janice O’Born David Peterson, Q.C. Sonya Savage Donna Scott Schuyler M. Sigel, Q.C. Paul Smetanin Allan R. Taylor James D. Watson, Ph.D. Peter G. White Andrew Williams Nina Kaiden Wright Adam H. Zimmerman, O.C. Scientific Advisory Committee Stanley Read, M.D., Ph.D., F.R.C.P.(C.) Chair Mark Wainberg, Ph.D. Co-Chair

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I may not look like Elizabeth Taylor but I got Bank Presidents and CEOs to make major contributions that put this charity on the map.

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– The Late Bluma Appel, Founding Member of CANFAR

Alan Cochrane, Ph.D. Karen Copeland, Ph.D. Norbert Gilmore, M.D., Ph.D. Eudice Goldberg, M.D., F.R.C.P.(C) Michael Grant, Ph.D. Sean Hosein Chen Liang, Ph.D. Mona Loutfy, M.D., F.R.C.P.(C), M.P.H. Paul Sandstrom, Ph.D. Cecile Tremblay, M.D., F.R.C.P.(C.) Sharon Walmsley, M.D., M.Sc., F.R.C.P.(C) National Spokesperson Valerie Pringle Executive Director Kerry Whiteside

CANFAR Donors

CANFAR is extremely grateful to the many individuals, corporations, foundations and groups who are committed to the helping us end AIDS through research, through their philanthropic support and sponsorships. The following list reflects total individual and organizational cash gifts in the 2008/2009 fiscal year. Thank you!

If your name has been omitted, please accept our sincerest apologies and contact Sherrie James at sjames@canfar.com or 1-800-563-CURE (2873) ext. 28

Research Partners An annual gift of $1,000 or more qualifies an individual as a Research Partner. We acknowledge the following individuals for their leadership and generosity in the fight against HIV/AIDS. $25,000 and above Andrew and Valerie Pringle James and Barbara Stewart $10,000 – $24,999 Mark Bridges Edward and Barbara Smith $5,000 – $9,999 Deborah D’Arcy Dr. J. Lawrence Gitterman Bill C. Graham James & Lynn Hubbs David LeGresley Tristan Michela Patricia Olasker Moris Pilla Grace M. Vidal-Ribas $1,000 – $4,999 Catherine Albertson Ron Atkinson

Paul and Kaye Beeston Frederick A. Blain Paul Blundy Beverley Browne Betty Butler James Byrd Gordon Capern Guy and Margaret Carr-Harris Barry M. Cooper Brian Cornelson Stephen R. Coxford Mark Daitchman Peter J. Devine Robert D. Dingwall Richard P. Ellis Amirah El-Safty Michel Fortier Howard Franklin Janet and Bob Gouinlock Stephanie A. Grubesic Nancy and Richard Hamm Suzanne Johnson Alexei Kamychev Michael Lee K. Kellie Leitch Jerry and Joan Lozinski David Lukin Patti A. MacNicol Thomas McGillis Jim and Elaine McGivern

Charles and Lore Ormrod Mark J. Redmond Susan Rimmer William Scott Robinson Michael E. Royce Randy Savela Gary Shieck Robert A. Stewart Mary M. Thomson Quig Tingley David L. Torrey John Tory Leeanne Weld Kostopoulos and Chris Kostopoulos Julia West and Richard Wernham Ray Williams Rick and Cheryl Wright Mark Young 6 anonymous donors Leading Institutional Supporters of Research CANFAR Leading Institutional Supporters of Research are corporations, foundations and groups who have donated $1,000 or more to CANFAR’s Research Grant Program during our 2008/2009 fiscal year. $25,000 and above Great-West Life, London Life & Canada Life RBC Foundation $10,000 – $24,999 National Bank Financial Group & National Bank of Canada S. A. Armstrong Limited The Peter and Shelagh Godsoe Family Foundation 1 anonymous donor

$5,000 – $9,999 Kathnan Investments Limited Rothmans, Benson & Hedges Inc. The Sixty Three Foundation T101 Ltd. The Calgary Foundation Trinity Development Group Inc. $1,000 – $4,999 Aboriginal Peoples Television Network Abraham and Malka Green Foundation Bell Employee Giving Program BMO Employee Charitable Foundation CANDEAL CAW Local 2002 Janssen-Ortho Inc. Nixon Charitable Foundation Ruby and Edwardh Barristers TD Bank Financial Group Telus Corporation The Charitable Gift Funds Canada Foundation The D. H. Gales Family Charitable Foundation of Toronto The Law Society of Upper Canada The Norman and Margaret Jewison Charitable Foundation Wawanesa Insurance Company Make a Lasting Gift Many concerned individuals choose to support HIV/AIDS research with a planned gift of life insurance, a gift of annuity or through a bequest to CANFAR. Planned gifts are vital to helping fund Canadian researchers until an end to AIDS is found. It is with sincere thanks that we recognize the following estates for the 2008/2009 fiscal year: Estate of Dr. Edward S. Kamski Estate of Leo Paul Ramsperger

CANFAR Annual Report 2008/2009

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CANFAR Donors Supporters CANFAR Supporters are comprised of individuals, corporations, foundations and groups who have donated $500 $999 throughout the 2008/2009 fiscal year. $500 – $999 Andrew Abbott David Asher Ralph Barcan Earl Bederman and Anne McPherson Walter M. and Lisa Balfour Bowen Derek Cook Michael B. C. Davies Marcus Doyle Mike Dupee EnCana Cares Foundation Michael and Brenda Evans Karamjeet Gill Christian Hensen Barry Holmes Robert Hoppenheim E. L. Hubert IBM Employees’ Charitable Fund Stephen E. Langlois Robert and Patricia Lord Adrian Luces David Lyall Manulife Financial Brad Meredith Murray Neal Michael Norman Michael O’Keeffe OPG Employee’s & Pensioner’s Charity Trust Shelley Porter Neville Poy Inez Rodrigues Morgan Russell Mr. and Mrs. Robert Rutherford Edward Saunders Mr. and Mrs. Gard Shelley

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C. Alexander Squires Shelly Steeves Suzanne Stovel Barbara Stymiest The Jewish Foundation of Manitoba Warner Bros. Entertainment Canada Inc. Diana Woodhead 2 anonymous donors Operational Supporters Susan Anderson Ansell Canada Inc. Cadbury Adams Canada Inc. Gordon Capern Michael Cress Patricia Olasker National Bank Financial Group The Dominion of Canada General Insurance Company K. Kellie Leitch MuchMusic Ontario College of Art & Design Perform Marketing Valerie Pringle Sapient Gareth Seltzer Seneca College Weber Shandwick Worldwide If you are a United Way donor, please note that we often receive an aggregated list from the United Way which does not contain any donor information. To ensure we have your current information and are able to recognize our valuable donors, please contact Sherrie James at sjames@ CANFAR.com or 1-800-563-2873.

Thank you.

AIDSbeat 2008 Presenting Sponsor Laurel Hill Advisory Group

Gold Sponsors Agnico-Eagle Mines Limited Platinum Legal Group Inc The Robert J. Gemmell Family Foundation ZSA Legal Recruitment Limited Silver Sponsors Browne & Co. Inc. Carswell/Lexpert CNW Daniel et Daniel Event Creation & Catering Ernst & Young Precedent Magazine RR Donnelley James and Barbara Stewart The Schad Family The National Post Bronze Sponsors Computershare Trust Company of Canada Cole & Partners Crawford Class Action Services Fuller Landau LLP Georgeson Manulife Financial Navigant Consulting Network Reporting and Mediation RBC Law Group Law Firm Leaders Bennett Jones LLP (Toronto) Blake, Cassels & Graydon LLP Borden Ladner Gervais LLP Cassels Brock & Blackwell LLP Davies Ward Phillips & Vineberg LLP Fraser Milner Casgrain LLP Goodmans LLP Gowling Lafleur Henderson LLP Heenan Blaikie LLP Lax O’Sullivan Scott LLP

Lenczner Slaght McMillan LLP Ogilvy Renault LLP (Toronto) Osler, Hoskin & Harcourt LLP Paliare Roland Rosenberg Rothstein LLP Skadden, Arps, Slate, Meagher & Flom LLP Torys LLP Tough & Podrebarac LLP Law Firm Supporters Basman Smith LLP Davis Moldaver Epstein Cole LLP Fenton Smith Barristers Filion Wakely Thorup Angeletti LLP Greenspan Humphrey Lavine Gilbert’s LLP Henein & Associates Miller Thomson LLP Teplitsky, Colson LLP In Kind Sponsors Almost Naked Astral Media Outdoor, L.P. Beauties of Canada Belvedere Vodka Designing Trendz Elizabeth A. Huggesen Kool Haus Law Times Light Language Media National Speakers Bureau Nine One One Maxim Technologies Ottawa Senators Hockey Club Paliare Roland Rosenberg Rothstein LLP Porter Airlines RAINA+WILSON Skin FX Toronto The Lawyers Weekly The Mod Club

CANFAR Donors Bloor Street Entertains 2008 CANFAR thanks the exceptional individuals and organizations whose efforts surrounding the events of Bloor Street Entertains 2008 were nothing short of extraordinary.

Media Sponsor Zoom Media Magazine and Online Sponsor Toronto Life Magazine

Event Planning Sponsor David Vallee Entertains

Table Sponsors Jim Beattie and friends BMO Financial Group Cineplex Media CresaPartners LLC Davies Ward Phillips & Vineberg LLP Dersean Investments Limited Export Packers Co. Ltd. Gluskin Sheff and Associates Inc. Goodmans LLP GovanBrown Construction Managers Haywood Securities Inc. HSBC Securities (Canada) Inc. Knightsbridge Human Capital Management Inc. Manulife Centre McDonald’s Restaurants of Canada Limited Medcan Health Management Tristan Michela and friends Miller Bernstein National Bank Financial Group Owens Wright LLP Paliare Roland Rosenberg Rothstein LLP Pinedale Properties Andrew and Valerie Pringle RBC Foundation Richter & Associates Riocan Real Estate Investment Trust Roy Foss Motors Sterling Silver Developments TD Canada Trust Central Ontario Region The Sorbara Group The Zukerman Family Foundation

Design Sponsor Dinnick & Howells

In Kind Sponsor ONESTOP Toronto Inc.

Presenting Sponsor BMO Financial Group Platinum Sponsor Sun Life Financial Entertainment and Image Sponsor Rémy Martin Transportation Sponsor Magna International Inc. Gold Sponsors ALDO Groupe Inc. Chair-man Mills Limited Holt Renfrew Labatt Breweries of Canada Manulife Centre Sentry Select Howard Sokolowski and Linda Frum Print Sponsor The Printing House Ltd. Corporate Champions The Hon. Margaret McCain 1 anonymous donor PR Sponsor Weber Shandwick Worldwide

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We are proud to give our support to a Canadian organization that has already made significant

contributions towards finding a cure for AIDS and we hope that you will join us.

– Howard Sokolowski and Linda Frum, longtime supporters and Co-Chairs of Bloor Street Entertains 2008

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Chefs Richard Andino, Flow Restaurant & Lounge Ted Corado, c5 Greg Couillard & David Nganga, Spice Room & Chutney Bar Jayne Dunsmore, Jayne’s Gourmet Catering Roberto Fracchioni, Millcroft Inn & Spa Keith Froggett, Scaramouche David Hill, 10tation Event Catering Jason Inniss & Bertrand Alépée, Amuse-Bouche Derek Kennedy, Eight Wine Bar Jamie Kennedy, Jamie Kennedy at the Gardiner Brian J. King & Simon Kattar, à la Carte Kitchen Inc. Martin Kouprie, Pangaea Bradley MacDonald, Sassafraz G.Q. Pan, Blowfish Restaurant & Sake Bar Marisa Rocca, Sotto Sotto Chris Scott, One Eleven Yorkville Tawfik Shehata, Vertical Restaurant & Bar Marc Thuet, Bite Me! Corbin Tomaszeski, holt’s café Trevor Wilkinson, Trevor Kitchen and Bar Michael Wilson, Crush Wine Bar Bruce Woods, Catering By Centro Chris Zielinski, Ultra Supper Club Venues Bang & Olufsen BOSS Hugo Boss The Carlu Cartier Daniel Espinosa Studio Escada Ferrari Maserati of Toronto The Gardiner Museum of Ceramic Art george C. Toronto Harry Rosen Inc. Holt Renfrew HUGO Hugo Boss Impressions Art Gallery

Liss Gallery McKinsey & Company Mindham Fine Jewellery Minto St. Thomas Showroom Montblanc Boutique Toronto NOIR Ridpath’s Fine Furniture Roots Canada Royal Ontario Museum ROM Dinosaur Gallery Swarovski Canada Tiffany & Co. Florists Astra Florists Bayview Blossoms Inc Bloom: The Flower Company Church Street Flowers David Vallee Entertains David W. White Flowers Demarco-Perpich Fiori Floral Designs Florigens Design Forget-me-not Flower Shoppe Fresh Floral Creations Hatcher Florist Ltd. Ladybug Florist In the Village Peter Paul’s Flowers Quince Flowers Limited San Remo Florist Inc Teatro Verde Thriving Metropolis Urban Eden Flower Shoppe Beverage Sponsors Dan Aykroyd Wines Diamond Estates Giovello Stella Artois Dessert Lounge Sponsors Dufflet Pastries Incorporated Krups Canada

CANFAR Annual Report 2008/2009

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CANFAR Donors Party Design & Decor Seneca College Event Management - Exhibit & Design Program Additional Event Services Meeting Hosts Holt Renfrew Models generously donated by Elite Model Management Rental Companies Chair-man Mills Limited Exclusive Affair Rentals Performers John Alcorn Jenny Burke Daniel Panetta Richard Whiteman DJ We Do DJ Welcoming Video Production Buck Productions Auction Donors Baronesse Cosmetiques Anthony J. Batten Bryan Joseph Belanger Bell Canada Birks Bite Catering Andy Body Body Clinic Bousada Joseph Boyden Brassaii Restaurant Olga Bressan Jonathan Brett Burberry Canadian Traffic Network Cartier Catherine Curtis Designs Anne-Marie Ceballo-Jones Charles MacPherson & Associates

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Claus Feser Haute Coiffure CN Tower Patti Cooke Alison Dalglish-Pottow Davids Diamond Estates Wine Becky Di Leo Indrani de Silva Ed Hardy Canada Eleven Boutique Elizabeth Grant International Envers Chapin Gallery Extreme Fitness Fairmont Royal York Hotel Roger Fish Farley Flex Four Seasons Hotel, Toronto Fran Hill Gallery Grano Group SEB Guerlain Hammam Spa Hazel, Luxury for Women Alan Hanlon Holt Renfrew Howard Sokolowski & Linda Frum Hugo Nicholson Il Fornello Restaurants Impressions Art Gallery Jasmine’s Fine Jewellery James and Barbara Stewart Joshua Jensen Nagel, JJN Studios Inc. Jessica Jensen Incorporated Joan Eiley & Associates John de Jong Jewellery Josephson Opticans Ana Jurpik Michele Kambolis Beret Kitkeby Krups Canada Kumari’s Terrye Kupev Peter Laventhall

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CIBC is proud to partner with Have a Heart in its efforts to educate young people about how HIV/AIDS can affect them personally and about the impact this pandemic having globally.

- CIBC, Sponsor of CANFAR’s Have a Heart Campaign

Paul Lewis Liss Gallery Living Arts Design Lululemon Athletica William MacDonald Manor Landscaping and Property Maintenance Inc. Mark Lash Jewellery Marlowe Medcan Clinic Morton’s The Steak House New Era Fitted Hats New Vision Home Improvements Old Spaghetti Factory Amanda M. O’Reilly Park Hyatt Hotel Pier 4 Storehouse Restaurant Plain & Simple Andrew and Valerie Pringle Progressive Fine Art Pusateri’s Fine Foods Quasar Mode Rapp Optical Rémy Martin Renaissance Toronto Hotel Downtown Research In Motion Ltd. Richtree Inc. Ridpath’s Fine Furniture Rob MacDougall Art Robin Barker Hair’Sociates Rosemarie Louie Royal de Versailles Royal Porcupine Productions Salon Daniel and Spa Salvatore Leonetti Salon Secrett Jewel Salon Silvershadow Photographic Images SKIN Medical Spa Sobeys Urban Fresh Format Sony Pictures Home Entertainment Stavros Master Tailor Tarragon Theatre The Factory Theatre

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The Shameless Dames The Spoke Club Tiffany & Co. Trudelle Laker David Vallee Entertains Vintage Hotels Vision Group Of Companies Warner Home Video Brian Wickens Yorkville Club Young Minds Marketing Have a Heart 2009 National Supporters Ansell Canada Inc. - Lifestyles Cadbury Adams Canada Inc. – Dentyne CIBC Charitable Foundation CIBC Corporate Communications Freedom International Brokerage Inc. Great-West Life, London Life & Canada Life Co-operators General Insurance Company M.A.C AIDS Fund Media or Broadcast Sponsors MuchMusic Zoom Media Ontario College of Art and Design In Kind Sponsor Tosuta International Spring For Life 2009 Corporate Sponsors Astral Media Outdoor, L.P. Black Eyed Susan’s Florist Medcan Health Management ONESTOP Toronto Inc. PROUD FM 103.9 Zoom Media

Auditor’s Report

Condensed Balance Sheet

CANFAR’S Fiscal year 2008 - 2009

ASSETS

We have audited the balance sheet of the Canadian Foundation for AIDS Research (“CANFAR” or the “Foundation”) as at June 30, 2009 and the statements of revenue, expenses and changes in fund balances and cash flows for the year then ended.

These financial statements are the responsibility of CANFAR’s management.

Our responsibility is to express an opinion on these financial statements based on our audit.

Except as explained in the following paragraph, we conducted our audit in accordance with Canadian generally accepted auditing standards. Those standards require that we plan and perform an audit to obtain reasonable assurance whether the financial statements are free of material misstatement.

An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation.

CAPITAL ASSETS INVESTMENTS

In common with many non-profit organizations, CANFAR derives revenue from fundraising and awareness events and donations and bequests, the completeness of which is not susceptible to satisfactory audit verification. Accordingly, our verification of this revenue was limited to the amounts recorded in the records of CANFAR, and we were unable to determine whether any adjustments for unrecorded revenue might be necessary to fundraising and awareness events, donations and bequests revenue, deficiency of revenue over expenses and fund balances.

In our opinion, except for the effect of adjustments, if any, which we might have determined to be necessary had we been able to satisfy ourselves concerning the completeness of the revenue referred to in the preceding paragraph, these financial statements present fairly, in all material respects, the financial position of the Foundation as at June 30, 2009 and the results of its operations and its cash flows for the year then ended in accordance with Canadian generally accepted accounting principles.

Collins Barrow Toronto LLP Licensed Public Accountants Chartered Accountants September 18, 2009 Toronto, Ontario

2009

2008

CURRENT

Cash

Short-term investments

Accounts receivable

Prepaid expenses

197,386 603,656 67,835 30,383

$469,107 650,192 21,043 47,289

899,260

1,187,631

9,823 736,914

2,424 736,914

1,645,997

1,926,969

CURRENT LIABILITIES

Accounts payable

Grants payable

40,451 762,457

52,540 1,037,562

802,908

1,090,102

DEFERRED CONTRIBUTIONS

123,500

115,000

926,408

1,205,102

GENERAL

Invested in capital assets

Other

9,823 (27,148)

2,424 (17,471)

(17,325)

(15,047)

ENDOWMENT

736,914

736,914

719,589

721,867

$1,645,997

$1,926,969

LIABILITIES

FUND BALANCES

To receive a copy of our full audited financial statements, please contact Lynne Butler at lbutler@CANFAR.com or 1-800-563-CURE (2873), ext. 22.

CANFAR Annual Report 2008/2009

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CANFAR volunteers

C

CANFAR Volunteers

Thank you to each and every CANFAR volunteer. Together, we’ll end AIDS through research.

Volunteer of the Year: Gord Capern

Awards were presented to the following individuals and organizations to honour their outstanding dedication to CANFAR and to HIV/AIDS research and awareness:

The Heart Award: Earl Haig Secondary School The Award for Innovation: Medcan Health Management The CANFAR Event Award: Kim Roberts The Executive Director’s Award: Dr. Stanley Read

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CANFAR Clubs

The CANFAR Volunteer Awards: June 8, 2009

The Chairman’s Award: Patti MacNicol

Canadian HIV/AIDS research scientists. We believe that research is the only path to finding a cure and we remain committed to CANFAR in their contribution to this end. - Duncan Jackman, Jackman Foundation

Jason Stewart also highlighted individuals who continue to show exceptional commitment to CANFAR: Susan Anderson, June Brookes, Anne-Marie Ceballo-Jones, Andrew Grimes and Barb Newby.

The incredibly generous support of CANFAR volunteers is what allows us to fulfill our mission. As Bill Clinton famously said, “Volunteering is an act of heroism on a grand scale…

It does more than help people beat the odds; it changes the odds.”

The Volunteer of the Year Award: Gord Capern

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Our family has been supporting CANFAR for over ten years and proudly “ donate office space to them to allow them to do the important work of funding

At universities and colleges across Canada, CANFAR Clubs are establishing creative ways to raise money and engage their fellow students! The CANFAR Clubs are a crucial aspect of the overall CANFAR mission; they help to spread awareness in the most vulnerable age bracket and increase recognition for the importance of AIDS Research in Canada.

Students work together to raise funds and awareness in whatever way they choose: parties, bake sales, guest speakers, video screenings, karaoke, and trivia are just a few examples of how students make CANFAR events their own. Through planning and organizing events, students gain valuable experience and knowledge about collaborating with other volunteers, approaching sponsors and vendors, and marketing to their peers and the general public.

Our CANFAR Clubs continue to grow on college and university campuses as each contingent gains momentum!

CANFAR Club at > Dalhousie University

CANFAR Annual Report 2008/2009

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Message from CANFAR’S President and Chair James K. (Jason) Stewart & Andrew M. Pringle James K. (Jason) Stewart President, CANFAR

Andrew M. Pringle Chair, Board of Directors, CANFAR

Now, more than ever, is the time for action.

The opportunities to create significant, lasting change by funding research and greater awareness are at hand.

Our news has been filled with promising gains in HIV/ AIDS research, both in Canada and abroad. Lives are being saved, quality of life is improving for people living with HIV/AIDS, and prevention messages are getting through.

In Canadian laboratories and in field research, efforts to find new treatments and vaccines are at an exciting juncture. Notable research advances have occurred, and additional breakthroughs can happen at any time – if we continue to fund these initiatives.

Meanwhile, new concerns are surfacing. While young people, Canadian aboriginal communities, and men who have sex with men remain at serious risk, selected other populations are now showing increased HIV/ AIDS incidence and prevalence.

CANFAR’s funding of psycho-social research helps to ensure that we know how to best address these issues. Our financing of critical research initiatives helps those already infected with HIV to improve their quality of life by addressing co-infections, symptoms, and side-effects. Our support for methods to prevent HIV/AIDS transmission is literally having a worldwide impact.

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Our flagship events also reached new heights, despite the difficult economic and financial environment. Our award-winning event Bloor Street Entertains came in with exceptional results, raising $366,000 in a year where others either postponed their major events or experienced significant declines. AIDSbeat 2008 rocked Toronto’s legal community, raising an impressive $236,000. And a rejuvenated Spring for Life campaign sold gerbera daisies and received sponsorships to the tune of $44,000.

In closing, thank you for your generous and ongoing support of CANFAR. The Canadian research we have funded makes a monumental difference in the lives of those living with HIV/AIDS, and for those who are at risk.

CANFAR will continue its efforts until solutions are found.

With a strong investment in research, you can be a valuable part of this solution.

Together, we can end AIDS.

Meanwhile, the success of Have-a-Heart merits highlighting as our national youth awareness program flourished again. We reached our goal of 1,500 schools and hundreds of thousands of students involved in each province and territory across the country. At the post-secondary level, CANFAR clubs grew to 24 clubs at colleges and universities nation-wide.

The new fiscal year offers much promise. We continue to benefit from the dedicated efforts of our Executive Committee, Board, Advisory Council and other volunteers. We have also carefully and selectively added to CANFAR’s professional staff to enable more national fundraising, increased donor marketing and other outreach initiatives.

These initiatives were constrained last year by our expense reductions given the challenging economic situation.

CANFAR Annual Report 2008/2009

Together we can

CANFAR is committed and working hard to provide funding for Canadian HIV/AIDS research. Despite the major impacts of Canada’s recession and extraordinary financial markets during much of our fiscal year, your generosity enabled us to fund 13 grants for Canadian HIV/AIDS research teams.

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The sustainable answer to the AIDS crisis will be found in research.

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